ubenimex and Disease Models, Animal

Topics: Animals; Antineoplastic Agents; Binding Sites; CD13 Antigens; Cell Line, Tumor; Cell Proliferation; Click Chemistry; Disease Models, Animal; Human Umbilical Vein Endothelial Cells; Humans; Leucine; Liver Neoplasms; Lung Neoplasms; Mice; Molecular Docking Simulation; Neovascularization, Physiologic; Protease Inhibitors; Protein Structure, Tertiary; Structure-Activity Relationship

Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, Spinal; Humans; Mice, Inbred C57BL; Mice, Knockout; Neurons; Pruritus; Receptors, Atrial Natriuretic Factor; Reproducibility of Results; Signal Transduction; Small Molecule Libraries

Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection

Topics: Animals; Disease Models, Animal; Female; Kinetics; Leucine; Leukocytes; Leukotriene B4; Lymph Nodes; Lymphatic Vessels; Lymphedema; Male; Mice; Mice, Inbred C57BL; Protease Inhibitors

Topics: Animals; Antineoplastic Agents; Apoptosis; Autophagosomes; Autophagy; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Dose-Response Relationship, Drug; Gene Knockdown Techniques; Glioma; Humans; Leucine; Mice; Models, Biological; Nuclear Proteins; Proto-Oncogene Proteins c-akt; RNA-Binding Proteins; Signal Transduction; Transcription Factors; Xenograft Model Antitumor Assays

Topics: Animals; Benzopyrans; Carboxylic Acids; Choroidal Neovascularization; Disease Models, Animal; Eye; Eye Injuries; Hydroxyurea; Indoles; Lasers; Leucine; Leukotriene B4; Macrophages; Macular Degeneration; Male; Mice; Mice, Knockout; Neovascularization, Pathologic; Receptors, Leukotriene B4; Signal Transduction

Topics: Adult; Aged; Animals; Antibiotics, Antineoplastic; Biomarkers; Cell Line, Tumor; Colorectal Neoplasms; Disease Models, Animal; Epoxide Hydrolases; Female; Gene Expression; Humans; Immunohistochemistry; Leucine; Male; Mice; Mice, Knockout; Middle Aged; Models, Biological; Neoplasm Staging; Prognosis; Receptors, Leukotriene B4; Signal Transduction; Xenograft Model Antitumor Assays

Topics: Adenocarcinoma; Animals; Antibiotics, Antineoplastic; Arachidonate 5-Lipoxygenase; Cell Transformation, Neoplastic; Cyclooxygenase Inhibitors; Disease Models, Animal; Epoxide Hydrolases; Esophageal Neoplasms; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Inflammation; Leucine; Leukotriene A4; Neoplasms; Signal Transduction; Up-Regulation

Topics: Adenocarcinoma; Anastomosis, Surgical; Animals; Antibiotics, Antineoplastic; Blotting, Western; Chemoprevention; Disease Models, Animal; Duodenum; Epoxide Hydrolases; Esophageal Neoplasms; Esophagus; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Incidence; Inflammation; Leucine; Leukotriene A4; Rats; Stomach; Treatment Outcome; Up-Regulation

Topics: Animals; Apoptosis; Birth Weight; Blood Pressure; Disease Models, Animal; Female; Gestational Age; In Situ Nick-End Labeling; Leucine; Organ Size; Placenta; Pre-Eclampsia; Pregnancy; Proteinuria; Rats; Rats, Wistar

Topics: Adjuvants, Immunologic; Animals; Antibody Formation; Bacterial Infections; Disease Models, Animal; Drug Evaluation, Preclinical; Escherichia coli Infections; Female; Leucine; Listeriosis; Macrophages; Mice; Salmonella Infections; Urinary Tract Infections

Topics: Abscess; Amino Acids; Aminopeptidases; Animals; Anti-Bacterial Agents; Bacteroidaceae Infections; Carbon Radioisotopes; Cell Line; Cell Movement; Cell Survival; Collagen; Colony Count, Microbial; Culture Media; Disease Models, Animal; Dose-Response Relationship, Drug; Epithelial Cells; Gelatinases; Guinea Pigs; Humans; Keratinocytes; Leucine; Peptides; Porphyromonas gingivalis; Protease Inhibitors; Radiopharmaceuticals

Topics: Aminopeptidases; Animals; Anti-Bacterial Agents; Cyclohexanes; Disease Models, Animal; Encephalitozoon cuniculi; Encephalitozoonosis; Enzyme Inhibitors; Fatty Acids, Unsaturated; Female; Leucine; Mice; Mice, Nude; O-(Chloroacetylcarbamoyl)fumagillol; Parasitic Sensitivity Tests; Peptides; Sesquiterpenes

Topics: Animals; Captopril; Disease Models, Animal; Ferrets; In Vitro Techniques; Influenza A virus; Leucine; Leupeptins; Metalloendopeptidases; Muscle Contraction; Muscle, Smooth; Neprilysin; Orthomyxoviridae Infections; Thiorphan; Tiopronin; Trachea

Topics: Adjuvants, Immunologic; Animals; Chronic Disease; Disease Models, Animal; Drug Evaluation, Preclinical; Humans; Immunotherapy; Infections; Leucine; Lymphocytes; Macrophage Activation; Neoplasms, Experimental