Page last updated: 2024-08-25

ubenimex and Cancer of Liver

ubenimex has been researched along with Cancer of Liver in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (83.33)24.3611
2020's1 (16.67)2.80

Authors

AuthorsStudies
Cao, J; Huang, Y; Li, Y; Liang, X; Ma, C; Wu, P; Xu, W; Zhang, Y1
Cao, J; Ding, Q; Gao, Q; Gao, S; Kong, X; Liang, X; Ma, C; Wang, B; Xu, W; Yan, Y; Zang, J; Zhang, Y; Zhao, C1
Hou, X; Jia, G; Jiang, Y; Li, P; Li, X; Tan, L; Wang, X; Xu, W; Yue, K; Zhang, J; Zhang, L; Zhang, Z1
Dou, C; Fang, C; Fu, X; Li, D; Liu, H; Liu, Z; Wang, H; Wang, X; Wu, H; Xu, W; Zhang, J; Zhang, Y; Zhao, Y; Zhu, D1
Li, Y; Liu, XJ; Wu, SY; Zhen, YS; Zheng, YB1
Asaoka, T; Doki, Y; Eguchi, H; Gotoh, K; Kawamoto, K; Mori, M; Noda, T; Ogawa, H; Umeshita, K; Wada, H; Yamada, D; Yamashita, M1

Other Studies

6 other study(ies) available for ubenimex and Cancer of Liver

ArticleYear
Novel leucine ureido derivatives as aminopeptidase N inhibitors. Design, synthesis and activity evaluation.
    European journal of medicinal chemistry, 2016, Jan-27, Volume: 108

    Topics: Animals; Antineoplastic Agents; CD13 Antigens; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Humans; Inhibitory Concentration 50; Leucine; Liver Neoplasms; Lung Neoplasms; Mice; Molecular Structure; Neoplasms, Experimental; Structure-Activity Relationship

2016
Novel leucine ureido derivatives as aminopeptidase N inhibitors using click chemistry.
    Bioorganic & medicinal chemistry, 2018, 07-23, Volume: 26, Issue:12

    Topics: Animals; Antineoplastic Agents; Binding Sites; CD13 Antigens; Cell Line, Tumor; Cell Proliferation; Click Chemistry; Disease Models, Animal; Human Umbilical Vein Endothelial Cells; Humans; Leucine; Liver Neoplasms; Lung Neoplasms; Mice; Molecular Docking Simulation; Neovascularization, Physiologic; Protease Inhibitors; Protein Structure, Tertiary; Structure-Activity Relationship

2018
Design, synthesis and biological evaluation of hybrid of ubenimex-fluorouracil for hepatocellular carcinoma therapy.
    Bioorganic chemistry, 2021, Volume: 116

    Topics: Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Fluorouracil; Humans; Leucine; Liver Neoplasms; Molecular Structure; Structure-Activity Relationship

2021
BC-02 eradicates liver cancer stem cells by upregulating the ROS-dependent DNA damage.
    International journal of oncology, 2017, Volume: 51, Issue:6

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; DNA Damage; Female; Fluorouracil; Humans; Leucine; Liver Neoplasms; Mice; Mice, Nude; Neoplastic Stem Cells; Reactive Oxygen Species; Up-Regulation; Xenograft Model Antitumor Assays

2017
A multifunctional drug combination shows highly potent therapeutic efficacy against human cancer xenografts in athymic mice.
    PloS one, 2014, Volume: 9, Issue:12

    Topics: Adenocarcinoma; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blotting, Western; Carcinoma, Hepatocellular; Cell Proliferation; Dexamethasone; Dipyridamole; Electrophoresis, Gel, Two-Dimensional; Female; Humans; Leucine; Liver Neoplasms; Lung Neoplasms; Mice; Mice, Inbred BALB C; Mice, Nude; Proteomics; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tumor Cells, Cultured; Tumor Microenvironment; Vasodilator Agents; Xenograft Model Antitumor Assays

2014
A CD13 inhibitor, ubenimex, synergistically enhances the effects of anticancer drugs in hepatocellular carcinoma.
    International journal of oncology, 2016, Volume: 49, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Carcinoma, Hepatocellular; CD13 Antigens; Cell Cycle; Cell Line, Tumor; Cisplatin; Drug Synergism; Fluorouracil; Gene Expression Regulation, Neoplastic; Humans; Leucine; Liver Neoplasms; Neoplastic Stem Cells; Niacinamide; Phenylurea Compounds; Reactive Oxygen Species; Sorafenib

2016