Compounds > u 77779
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u 77779 and Cancer of Colon

u 77779 has been researched along with Cancer of Colon in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (50.00)18.2507
2000's2 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ebisu, H; Fukuda, Y; Furuta, H; Oomori, Y; Seto, S; Terashima, S1
Beerman, T; Cao, PR; McHugh, MM; Melendy, T1
Bai, S; Goodrich, DW1
Gibson, NW; Lee, CS1

Other Studies

4 other study(ies) available for u 77779 and Cancer of Colon

ArticleYear
The novel cyclopropapyrroloindole(CPI) bisalkylators bearing 3,3'-(1,4-phenylene)diacryloyl group as a linker.
    Bioorganic & medicinal chemistry letters, 1998, Aug-04, Volume: 8, Issue:15

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents, Alkylating; Benzylidene Compounds; Cell Division; Colonic Neoplasms; HeLa Cells; Humans; Mice; Pyrroles; Structure-Activity Relationship

1998
The DNA minor groove-alkylating cyclopropylpyrroloindole drugs adozelesin and bizelesin induce different DNA damage response pathways in human colon carcinoma HCT116 cells.
    Molecular cancer therapeutics, 2003, Volume: 2, Issue:7

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Benzofurans; Cell Cycle; Cellular Senescence; Colonic Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Cyclohexanecarboxylic Acids; Cyclohexenes; DNA Damage; DNA, Neoplasm; Dose-Response Relationship, Drug; Duocarmycins; Humans; Indoles; Signal Transduction; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Urea

2003
Different DNA lesions trigger distinct cell death responses in HCT116 colon carcinoma cells.
    Molecular cancer therapeutics, 2004, Volume: 3, Issue:5

    Topics: Aminoglycosides; Antibiotics, Antineoplastic; Antineoplastic Agents, Alkylating; Benzofurans; Cell Cycle; Cell Death; Cell Proliferation; Colonic Neoplasms; Cyclohexanecarboxylic Acids; Cyclohexenes; DNA Damage; Dose-Response Relationship, Drug; Duocarmycins; Enediynes; HCT116 Cells; Humans; Indoles; Inhibitory Concentration 50; Urea

2004
DNA damage and differential cytotoxicity produced in human carcinoma cells by CC-1065 analogues, U-73,975 and U-77,779.
    Cancer research, 1991, Dec-15, Volume: 51, Issue:24

    Topics: Antibiotics, Antineoplastic; Benzofurans; Carcinoma; Cell Death; Colonic Neoplasms; Cross-Linking Reagents; Cyclohexanecarboxylic Acids; Cyclohexenes; DNA Damage; Dose-Response Relationship, Drug; Duocarmycins; Humans; Indoles; Leucomycins; Lung Neoplasms; Plasmids; Tumor Cells, Cultured; Urea

1991