Page last updated: 2024-08-26

u 74389f and Disease Models, Animal

u 74389f has been researched along with Disease Models, Animal in 31 studies

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's15 (48.39)18.2507
2000's5 (16.13)29.6817
2010's10 (32.26)24.3611
2020's1 (3.23)2.80

Authors

AuthorsStudies
Kroupis, C; Lagiou, M; Papalois, A; Perlikos, F; Rizou, T; Toumpoulis, IK1
Karamatsoukis, SL; Karamperi, M; Nikiteas, N; Papadopoulos, O; Papalois, AE; Patsouris, E; Pittaras, T; Stasinopoulou, M; Stavridou, A; Trigka, EA; Tsarea, K; Zacharioudaki, A; Zografos, GC1
Agrogiannis, G; Alexakis, N; Bramis, I; Chrysikos, DT; Flessas, I; Katsarou, A; Korontzi, M; Papalois, AE; Patsouri, EE; Patsouris, ES; Psaltopoulou, T; Sergentanis, TN; Zagouri, F; Zografos, GC1
Panoulis, C; Papalois, A; Tauοutouzas, K; Zetaografos, G; Τsompos, C1
Agrogiannis, G; Antoniou, E; Arkadopoulos, N; Christoloukas, N; Margonis, GA; Papalois, AE; Patsouris, ES; Pikoulis, E; Theodoropoulos, G; Zografos, GC1
Agrogiannis, G; Bramis, I; Chrysikos, D; Flessas, I; Gioxari, A; Korontzi, M; Menenakos, E; Nonni, A; Papalois, A; Patsouris, E; Toutouzas, K; Zografos, G1
Panoulis, C; Papalois, A; Toutouzas, K; Tsompos, C; Zografos, G2
Panoulis, C; Papalois, A; Toutouzas, K; Triantafyllou, A; Tsompos, C; Zografos, G1
Chang, CH; Chang, HT; Chang, YT; Hsieh, KH; Huang, CI; Huang, MS; Liu, YC; Wann, SR1
Flessas, II; Papalois, AE; Toutouzas, K; Zagouri, F; Zografos, GC1
Boada, LD; Díaz, JM; Domínguez-Díez, A; García-Plaza, G; Hernández, JR; Navarro, D; Palomar, R; Zumbado, M1
Acka, G; Akin, A; Canakci, Z; Cermik, H; Kokpinar, S; Sen, A; Uzun, G; Yildirim, I; Yildiz, S1
Adamopoulos, S; Constadinidis, T; Kyriazi, A; Lambropoulou, M; Papadopoulos, K; Papadopoulos, N; Papalois, A; Simopoulos, C; Tsaroucha, AK; Vernadakis, S1
Altavilla, D; Ammendolia, L; Campo, GM; Canale, P; Caputi, AP; Ioculano, M; Saitta, A; Sperandeo, A; Squadrito, F; Squadrito, G1
Cross, RS; LeVine, SM; Lynch, SG; Milford, CM1
Haraldseth, O; Jones, RA; Lindboe, CF; Müller, TB; Oksendal, AN; Sebastiani, G; Unsgård, G1
Bernatowicz, A; Fontana, A; Frei, K; Koedel, U; Lorenzl, S; Pfister, HW1
Chan, P; Cook, D; Findlay, M; Vollrath, B1
De Nicola, AF; Gonzalez Deniselle, MC; Gonzalez, SL; Lima, AE; Piroli, GG1
Barry, SJ; Brown, SA; Drake, C; Enos, LR; Harmon, FA; Henry, P; Hildebrand, SV; Magliano, D; Nieto, J; Snyder, JR; Vatistas, NJ; Woliner, MJ1
Bahra, M; Hausen, B; Hewitt, CW; Morris, RE; Mueller, P; Ramsamooj, R1
Egusa, K; Haddad, J; Takoudes, TG1
De Nicola, AF; González Deniselle, MC; González, SL; Lima, AE; Wilkin, G1
Hurst, TS; Johnson, DH; Mayers, I; Miles, D; Saxena, A1
Harat, M; Kochanowski, J1
Barie, PS1
Ding, X; Nath, J; Shea-Donohue, T; Smallridge, R; Stojadinovic, A1
Abe, T; Komatsu, K; Kuwaki, K; Sohma, H2
De Nicola, AF; González Deniselle, MC; González, SL1

Reviews

3 review(s) available for u 74389f and Disease Models, Animal

ArticleYear
Effects of lazaroids on intestinal ischemia and reperfusion injury in experimental models.
    The Journal of surgical research, 2011, Volume: 166, Issue:2

    Topics: Animals; Antioxidants; Disease Models, Animal; Intestinal Mucosa; Intestines; Pregnatrienes; Reperfusion Injury

2011
Schemes against ischemia; solutions for reperfusion (injury)?
    Critical care medicine, 1999, Volume: 27, Issue:4

    Topics: Animals; Antioxidants; Disease Models, Animal; Drug Evaluation, Preclinical; Humans; Intestine, Small; Ischemia; Pregnatrienes; Rats; Reperfusion Injury; Risk Factors; Time Factors

1999
Cellular basis of steroid neuroprotection in the wobbler mouse, a genetic model of motoneuron disease.
    Cellular and molecular neurobiology, 2001, Volume: 21, Issue:3

    Topics: Animals; Disease Models, Animal; Mice; Mice, Neurologic Mutants; Motor Neuron Disease; Neuroprotective Agents; Pregnatrienes

2001

Trials

1 trial(s) available for u 74389f and Disease Models, Animal

ArticleYear
Effects of U-74389G, a novel 21-aminosteroid, on small intestinal ischemia and reperfusion injury in horses.
    American journal of veterinary research, 1996, Volume: 57, Issue:5

    Topics: Animals; Antioxidants; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Horse Diseases; Horses; Infusions, Intravenous; Intestinal Mucosa; Jejunum; Male; Malondialdehyde; Mesenteric Vascular Occlusion; Peroxidase; Pregnatrienes; Reperfusion Injury; Time Factors

1996

Other Studies

27 other study(ies) available for u 74389f and Disease Models, Animal

ArticleYear
Lazaroid (U-74389G) ameliorates lung injury due to lipid peroxidation and nitric oxide synthase-dependent reactive oxygen species generation caused by remote systematic ischemia-reperfusion following thoracoabdominal aortic occlusion.
    International journal of surgery (London, England), 2018, Volume: 55

    Topics: Animals; Antioxidants; Aorta, Thoracic; Arterial Occlusive Diseases; Disease Models, Animal; Lipid Peroxidation; Lung Injury; Male; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Pregnatrienes; Reactive Oxygen Species; Reperfusion Injury; Swine

2018
Beneficial Effect of U-74389 G and Sildenafil in An Experimental Model of Flap Ischemia/Reperfusion Injury in Swine. Histological and Biochemical Evaluation of the Model.
    Journal of investigative surgery : the official journal of the Academy of Surgical Research, 2020, Volume: 33, Issue:5

    Topics: Animals; Antioxidants; Disease Models, Animal; Drug Synergism; Humans; Male; Malondialdehyde; Oxidative Stress; Pregnatrienes; Reperfusion Injury; Sildenafil Citrate; Superficial Back Muscles; Surgical Flaps; Swine; Tumor Necrosis Factor-alpha

2020
The effect of U-74389G on pancreas ischemia-reperfusion injury in a swine model.
    The Journal of surgical research, 2014, Volume: 187, Issue:2

    Topics: Acute Disease; Animals; Antioxidants; Disease Models, Animal; Female; Male; Malondialdehyde; Oxidative Stress; Pancreatitis, Acute Necrotizing; Pregnatrienes; Random Allocation; Reperfusion Injury; Sus scrofa; Treatment Failure; Tumor Necrosis Factor-alpha

2014
The effect of the antioxidant drug "U-74389G" on oophoritis during ischemia reperfusion injury in rats.
    Anti-inflammatory & anti-allergy agents in medicinal chemistry, 2014, Volume: 13, Issue:2

    Topics: Animals; Antioxidants; Disease Models, Animal; Female; Oophoritis; Pregnatrienes; Rats; Rats, Wistar; Reperfusion Injury

2014
Effectiveness of sildenafil and U-74389G in a rat model of colitis.
    The Journal of surgical research, 2015, Volume: 193, Issue:2

    Topics: Animals; Antioxidants; Colitis; Colon; Disease Models, Animal; Drug Evaluation, Preclinical; Drug Therapy, Combination; Male; Malondialdehyde; Phosphodiesterase 5 Inhibitors; Piperazines; Pregnatrienes; Purines; Random Allocation; Rats, Wistar; Sildenafil Citrate; Sulfones; Trinitrobenzenesulfonic Acid; Tumor Necrosis Factor-alpha

2015
Effects of lazaroid U-74389G on intestinal ischemia and reperfusion injury in porcine experimental model.
    International journal of surgery (London, England), 2015, Volume: 13

    Topics: Animals; Antioxidants; Disease Models, Animal; Female; Male; Malondialdehyde; Models, Theoretical; Pregnatrienes; Reperfusion Injury; Swine; Tumor Necrosis Factor-alpha

2015
[The Effect of the Antioxidant Drug U-74389G on Magnesium Levels During Hypoxia-Reoxygenation Injury in Rats].
    Vestnik Rossiiskoi akademii meditsinskikh nauk, 2015, Issue:4

    Topics: Animals; Antioxidants; Disease Models, Animal; Female; Hypoxia; Magnesium; Pregnatrienes; Rats; Rats, Wistar; Reperfusion Injury

2015
Antioxidant 21-aminosteroid "U-74389G" ameliorates the short-time effect of hypoxia-reoxygenation on the platelet count in rats.
    Folia medica Cracoviensia, 2015, Volume: 55, Issue:1

    Topics: Animals; Antioxidants; Disease Models, Animal; Free Radical Scavengers; Hypoxia; Platelet Count; Pregnatrienes; Rats; Rats, Wistar; Reperfusion Injury

2015
Comparison of the Acute Hematopoietic Capacities of Erythropoietin and U-74389G Concerning Hematocrit Levels.
    Cardiovascular & hematological disorders drug targets, 2017, 07-04, Volume: 17, Issue:1

    Topics: Animals; Antioxidants; Disease Models, Animal; Erythropoietin; Female; Hematocrit; Hematopoiesis; Humans; Hypoxia; Male; Pregnatrienes; Rats, Wistar; Reperfusion Injury

2017
The effects of lazaroid U-74389G in a rat sepsis model.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2011, Volume: 60, Issue:1

    Topics: Animals; Disease Models, Animal; Escherichia coli; Hemodynamics; Humans; Immunosuppressive Agents; Male; Placebos; Pregnatrienes; Rats; Rats, Sprague-Dawley; Sepsis; X-Rays

2011
Evaluation of the potential protective effect of 21-aminosteroid U-74389G on liver injury induced by reduced and prolonged partial hepatic ischaemia reperfusion in rats.
    Pharmacology & toxicology, 2003, Volume: 93, Issue:5

    Topics: Animals; Antioxidants; Disease Models, Animal; Ischemia; Liver; Male; Pregnatrienes; Rats; Rats, Sprague-Dawley; Reperfusion Injury

2003
Effect of combined therapy with hyperbaric oxygen and antioxidant on infarct volume after permanent focal cerebral ischemia.
    Physiological research, 2007, Volume: 56, Issue:3

    Topics: Animals; Antioxidants; Brain Ischemia; Combined Modality Therapy; Disease Models, Animal; Hyperbaric Oxygenation; Infarction, Middle Cerebral Artery; Male; Pregnatrienes; Rats; Rats, Wistar

2007
The effect of U-74389G on liver recovery after acute liver ischemia-reperfusion injury in a swine model.
    The Journal of surgical research, 2009, Volume: 151, Issue:1

    Topics: Acute Disease; Animals; Antioxidants; Disease Models, Animal; Hepatic Artery; Liver; Male; Malondialdehyde; Portal Vein; Pregnatrienes; Recovery of Function; Reperfusion Injury; Swine; Time Factors; Tumor Necrosis Factor-alpha

2009
Improved survival and reversal of endothelial dysfunction by the 21-aminosteroid, U-74389G in splanchnic ischaemia-reperfusion injury in the rat.
    British journal of pharmacology, 1995, Volume: 115, Issue:3

    Topics: Acetylcholine; Analysis of Variance; Animals; Antioxidants; Blood Pressure; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Leukocyte Count; Leukopenia; Lipid Peroxidation; Male; Malondialdehyde; Mesenteric Arteries; Mesenteric Vascular Occlusion; Nitroprusside; Peroxidase; Pregnatrienes; Rats; Reperfusion Injury; Splanchnic Circulation; Steroids, Heterocyclic; Survival Rate; Tumor Necrosis Factor-alpha

1995
Testing lazaroids U-74389G and U-83836E for therapeutic value in experimental allergic encephalomyelitis in the Lewis rat.
    Research communications in molecular pathology and pharmacology, 1995, Volume: 87, Issue:3

    Topics: Animals; Antioxidants; Chromans; Disease Models, Animal; Drug Evaluation, Preclinical; Encephalomyelitis, Autoimmune, Experimental; Female; Free Radical Scavengers; Male; Multiple Sclerosis; Piperazines; Pregnatrienes; Rats; Rats, Inbred Lew

1995
Perfusion and diffusion-weighted MR imaging for in vivo evaluation of treatment with U74389G in a rat stroke model.
    Stroke, 1995, Volume: 26, Issue:8

    Topics: Animals; Antioxidants; Cerebrovascular Disorders; Disease Models, Animal; Magnetic Resonance Angiography; Male; Perfusion; Pregnatrienes; Rats; Rats, Wistar

1995
Protective effect of a 21-aminosteroid during experimental pneumococcal meningitis.
    The Journal of infectious diseases, 1995, Volume: 172, Issue:1

    Topics: Animals; Antioxidants; Astrocytes; Body Water; Brain; Cells, Cultured; Cerebrospinal Fluid; Cerebrovascular Circulation; Disease Models, Animal; Interferon-gamma; Interleukin-6; Intracranial Pressure; Iron; Leukocyte Count; Leukocytes; Lipid Peroxidation; Lipopolysaccharides; Macrophages, Peritoneal; Male; Meningitis, Pneumococcal; Nitric Oxide; Pregnatrienes; Rats; Rats, Wistar; Recombinant Proteins; Time Factors; Tumor Necrosis Factor-alpha

1995
Lazaroids and deferoxamine attenuate the intracellular effects of oxyhaemoglobin in vascular smooth muscle.
    Cardiovascular research, 1995, Volume: 30, Issue:4

    Topics: Animals; Antioxidants; Calcium; Cell Line; Cell Survival; Chelating Agents; Chromans; Deferoxamine; Disease Models, Animal; Dogs; Female; Free Radical Scavengers; Hydrogen Peroxide; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Iron; Ischemic Attack, Transient; Male; Muscle Contraction; Muscle, Smooth, Vascular; Oxyhemoglobins; Piperazines; Pregnatrienes; Subarachnoid Hemorrhage

1995
The 21-aminosteroid U-74389F increases the number of glial fibrillary acidic protein-expressing astrocytes in the spinal cord of control and Wobbler mice.
    Cellular and molecular neurobiology, 1996, Volume: 16, Issue:1

    Topics: Adrenalectomy; Amyotrophic Lateral Sclerosis; Animals; Astrocytes; Binding, Competitive; Cell Division; Corticosterone; Dexamethasone; Disease Models, Animal; Female; Genes, Recessive; Glial Fibrillary Acidic Protein; Homozygote; Male; Mice; Mice, Neurologic Mutants; Muscular Atrophy, Spinal; Pregnatrienes; Receptors, Glucocorticoid; Reference Values; Spinal Cord

1996
Donor treatment with the lazeroid U74389G reduces ischemia-reperfusion injury in a rat lung transplant model.
    The Annals of thoracic surgery, 1997, Volume: 64, Issue:3

    Topics: Airway Resistance; Animals; Antioxidants; Disease Models, Animal; Edema; Ischemia; Lung; Lung Compliance; Lung Transplantation; Male; Organ Preservation; Organ Size; Oxygen; Pregnatrienes; Pulmonary Alveoli; Pulmonary Gas Exchange; Rats; Rats, Inbred Lew; Reperfusion; Reperfusion Injury; Survival Rate; Tissue Donors; Vascular Resistance; Weight Gain

1997
Effects of 21-aminosteroid U-74389G on acute otitis media in a guinea pig model.
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 1998, Volume: 118, Issue:1

    Topics: Acute Disease; Animals; Antioxidants; Disease Models, Animal; Ear, Middle; Free Radicals; Guinea Pigs; Lipid Peroxidation; Lipid Peroxides; Male; Malondialdehyde; Mucous Membrane; Otitis Media; Pneumococcal Infections; Pregnatrienes

1998
The 21-aminosteroid U-74389F attenuates hyperexpression of GAP-43 and NADPH-diaphorase in the spinal cord of wobbler mouse, a model for amyotrophic lateral sclerosis.
    Neurochemical research, 1999, Volume: 24, Issue:1

    Topics: Amyotrophic Lateral Sclerosis; Animals; Antioxidants; Dihydrolipoamide Dehydrogenase; Disease Models, Animal; Female; GAP-43 Protein; Gene Expression Regulation; Humans; Male; Mice; Mice, Neurologic Mutants; Motor Neurons; Pregnatrienes; Spinal Cord

1999
Systemic thermal injury in anesthetized rabbits causes early pulmonary vascular injury that is not ablated by lazaroids.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1999, Volume: 46, Issue:2

    Topics: Analysis of Variance; Anesthesia, General; Animals; Antioxidants; Bronchoalveolar Lavage Fluid; Burns; Disease Models, Animal; Hemodynamics; Leukocytes; Lipid Peroxidation; Lung; Neutrophils; Pregnatrienes; Prospective Studies; Pulmonary Alveoli; Pulmonary Gas Exchange; Rabbits; Random Allocation; Respiratory Distress Syndrome; Single-Blind Method; Vascular Resistance

1999
Effect of treatment with 21-aminosteroid U-74389G and glucocorticoid steroid methylprednisolone on somatosensory evoked potentials in rat spinal cord during mild compression.
    Journal of neurotrauma, 1999, Volume: 16, Issue:2

    Topics: Afferent Pathways; Animals; Antioxidants; Disease Models, Animal; Evoked Potentials, Somatosensory; Male; Methylprednisolone; Neuroprotective Agents; Pregnatrienes; Rats; Rats, Wistar; Sciatic Nerve; Somatosensory Cortex; Spinal Cord; Spinal Cord Compression; Spinal Cord Injuries; Statistics, Nonparametric

1999
Anti-inflammatory effects of U74389F in a rat model of intestinal ischemia/reperfusion injury.
    Critical care medicine, 1999, Volume: 27, Issue:4

    Topics: Animals; Antioxidants; Dinoprostone; Disease Models, Animal; Drug Evaluation, Preclinical; Eicosanoids; Immunosuppressive Agents; Inflammation; Injections, Intravenous; Intestine, Small; Leukotriene B4; Male; Neutrophil Activation; Pregnatrienes; Prospective Studies; Random Allocation; Rats; Rats, Sprague-Dawley; Reperfusion Injury

1999
The effect of various doses of lazaroid U74389G on lung ischemia reperfusion injury.
    The Thoracic and cardiovascular surgeon, 1999, Volume: 47, Issue:2

    Topics: Animals; Antioxidants; Body Water; Disease Models, Animal; Dose-Response Relationship, Drug; Lipid Peroxidation; Lipid Peroxides; Lung; Lung Transplantation; Male; Organ Size; Pregnatrienes; Pulmonary Gas Exchange; Rats; Rats, Inbred Lew; Reperfusion Injury; Spectrometry, Fluorescence

1999
Improvement of ischaemia-reperfusion injury by lazaroid U74389G in rat lung transplantation model.
    Scandinavian cardiovascular journal : SCJ, 2000, Volume: 34, Issue:2

    Topics: Animals; Antioxidants; Disease Models, Animal; Lung Transplantation; Male; Pregnatrienes; Rats; Rats, Inbred Lew; Reperfusion Injury

2000