Page last updated: 2024-08-26

u 74006f and Reperfusion Injury

u 74006f has been researched along with Reperfusion Injury in 31 studies

Research

Studies (31)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	29 (93.55)	18.2507
2000's	1 (3.23)	29.6817
2010's	1 (3.23)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Flessas, II; Papalois, AE; Toutouzas, K; Zagouri, F; Zografos, GC	1
Ettinger, SL; Keown, PA; Scudamore, CH; Shackleton, CR; Toleikis, PF	1
Farhood, A; Fisher, MA; Jaeschke, H; Liu, P; McGuire, GM; Vonderfecht, SL	1
Gerdin, B; Haglund, U; Park, PO	1
D'Alecy, LG; Whitesall, SE; Zwemer, CF	1
Cosenza, CA; Cramer, DV; Cunneen, SA; Makowka, L; Tuso, PJ; Wang, HK	1
Oostveen, JA; Williams, LR	1
D'Alecy, LG; Frank, TS; Goldblum, JR; Stanley, JJ; Zelenock, GB	1
Blizzard, KK; Kirsch, JR; Koehler, RC; Maruki, Y; Traystman, RJ	1
Giacoia, GP	1
Gershuni, DH; Lopez, MA; Mohler, LR; Ohara, WM; Oyama, BK; Pedowitz, RA	1
Hao, E; Kneteman, NM; Rajotte, RV; Shapiro, AM	1
Boisvert, DP; Hall, ED	1
Jaeschke, H; Laskey, RE; Mathews, WR; McKenna, R; Wang, Y	1
Kanji, VK; Salahudeen, AK; Wang, C	1
Hamada, N; Kawashima, Y; Nemoto, A; Nomoto, M; Starzl, TE; Todo, S; Zhang, S; Zhu, Y	1
Ishizaki, N; Kobayashi, Y; Nemoto, A; Starzl, TE; Subbotin, V; Todo, S; Zhang, S; Zhu, Y	1
Spapen, H; Vincent, JL; Zhang, H	1
Chen, LE; Korompilias, AV; Seaber, AV; Urbaniak, JR	1
Burmester, GR; Buttgereit, F; Hiepe, F	1
Hillinger, S; Schmid, RA; Schöb, OM; Schoeberlein, A; Singer, T; Stammberger, U; Weder, W; Zollinger, A	1
Boehler, A; Hillinger, S; Schmid, RA; Schöb, OM; Stammberger, U; Weder, W; Zollinger, A	1
Krenn, CG; Pezawas, L; Pezawas, T; Plöchl, W; Pokorny, H; Steltzer, H	1
Alberto, P; Cerinic, MM; Falcini, F; Fernanda, F; Gabriele, S; Generini, S; Marco, MC; Pignone, A; Sergio, G; Simonini, G	1
Blizzard, KK; Helfaer, MA; Hurn, PD; Kirsch, JR; Koehler, RC; Traystman, RJ	1
Bjorling, DE; Galbreath, EJ; Lindsay, WA; Southard, JH; Stone, WC	1
Hall, ED; Sato, PH	1
Quirk, WS; Seidman, MD	1
Garnett, ME; Godin, DV; Ko, KM	1
Badylak, SF; Jeffries, M; Lantz, GC	1
Johnson, G; Lefer, AM	1

Reviews

5 review(s) available for u 74006f and Reperfusion Injury

Article	Year
Effects of lazaroids on intestinal ischemia and reperfusion injury in experimental models. The Journal of surgical research, 2011, Volume: 166, Issue:2 Topics: Animals; Antioxidants; Disease Models, Animal; Intestinal Mucosa; Intestines; Pregnatrienes; Reperfusion Injury	2011
Tirilazad mesylate attenuates the accumulation of neutrophils in ischemic gerbil brain. Annals of the New York Academy of Sciences, 1993, May-28, Volume: 679 Topics: Animals; Biomarkers; Brain; Cell Survival; Electron Transport Complex IV; Free Radical Scavengers; Gerbillinae; Ischemic Attack, Transient; Neurons; Neutrophils; Pregnatrienes; Reperfusion Injury	1993
Potential therapeutic value of lazaroids in endotoxemia and other forms of sepsis. Shock (Augusta, Ga.), 1997, Volume: 8, Issue:5 Topics: Animals; Antioxidants; Endothelium; Endotoxemia; Free Radical Scavengers; Glucocorticoids; Humans; Methylprednisolone; Pregnatrienes; Reperfusion Injury; Sepsis; Shock, Septic; Structure-Activity Relationship	1997
[The therapeutic potential of lazaroids (21-aminosteroids). A recent survey]. Deutsche medizinische Wochenschrift (1946), 1997, Oct-31, Volume: 122, Issue:44 Topics: Animals; Antioxidants; Brain Injuries; Brain Ischemia; Cell Membrane; Free Radical Scavengers; Free Radicals; Glucocorticoids; Humans; Ischemia; Lipid Peroxidation; Neuroprotective Agents; Pregnatrienes; Reperfusion Injury; Rheumatic Diseases; Spinal Cord; Spinal Cord Injuries; Steroids	1997
Emerging potentials for an antioxidant therapy as a new approach to the treatment of systemic sclerosis. Toxicology, 2000, Nov-30, Volume: 155, Issue:1-3 Topics: Antioxidants; Ascorbic Acid; beta Carotene; Endothelium, Vascular; Humans; In Vitro Techniques; Melatonin; Nitric Oxide; Oxidative Stress; Pregnatrienes; Probucol; Raynaud Disease; Reactive Oxygen Species; Reperfusion Injury; Resveratrol; Scleroderma, Systemic; Selenium; Stilbenes; Vitamin E	2000

Trials

1 trial(s) available for u 74006f and Reperfusion Injury

Article	Year
The use of the antioxidant tirilazad mesylate in human liver transplantation: is there a therapeutic benefit? Intensive care medicine, 1999, Volume: 25, Issue:6 Topics: Antioxidants; Female; Humans; Liver Transplantation; Male; Malondialdehyde; Pregnatrienes; Reperfusion Injury; Treatment Outcome	1999

Other Studies

25 other study(ies) available for u 74006f and Reperfusion Injury

Article	Year
Effect of a 21-aminosteroid, U74006F, on lipid peroxidation and glomerulotubular function following experimental renal ischemia. The Journal of surgical research, 1994, Volume: 57, Issue:4 Topics: Animals; Creatinine; Disease Models, Animal; Glomerular Filtration Rate; Kidney; Kidney Tubules; Lipid Peroxidation; Pregnatrienes; Random Allocation; Rats; Reperfusion Injury; Sodium; Superoxide Dismutase; Time Factors	1994
The 21-aminosteroid tirilazad mesylate protects against endotoxin shock and acute liver failure in rats. The Journal of pharmacology and experimental therapeutics, 1994, Volume: 271, Issue:1 Topics: Animals; Antioxidants; Lipid Peroxidation; Liver Failure, Acute; Male; Neutrophils; Pregnatrienes; Rats; Rats, Inbred F344; Reperfusion Injury; Shock, Septic; Tetradecanoylphorbol Acetate; Tumor Necrosis Factor-alpha	1994
Effects of a novel 21-aminosteroid or methylprednisolone in experimental total intestinal ischemia. Archives of surgery (Chicago, Ill. : 1960), 1994, Volume: 129, Issue:8 Topics: Animals; Evaluation Studies as Topic; Female; Free Radical Scavengers; Intestinal Mucosa; Intestines; Ischemia; Lipid Peroxides; Male; Pregnatrienes; Random Allocation; Rats; Rats, Wistar; Reperfusion Injury; Temperature	1994
Cardiopulmonary-cerebral resuscitation with 100% oxygen exacerbates neurological dysfunction following nine minutes of normothermic cardiac arrest in dogs. Resuscitation, 1994, Volume: 27, Issue:2 Topics: Animals; Central Nervous System Diseases; Dogs; Free Radical Scavengers; Heart Arrest; Lipid Peroxides; Male; Oxygen Inhalation Therapy; Pregnatrienes; Reactive Oxygen Species; Reperfusion Injury; Resuscitation; Time Factors	1994
Protective effect of the lazaroid U74006F in cold ischemia-reperfusion injury of the liver. Hepatology (Baltimore, Md.), 1994, Volume: 19, Issue:2 Topics: Animals; Cell Survival; Cells, Cultured; Cold Temperature; Disease Models, Animal; Endothelium, Vascular; Female; Free Radical Scavengers; Graft Survival; Lipid Peroxides; Liver; Liver Transplantation; Male; Organ Culture Techniques; Organ Preservation; Pregnatrienes; Random Allocation; Rats; Rats, Inbred Lew; Reperfusion Injury; Swine; Swine, Miniature	1994
Attenuation of renal reperfusion injury in rats by the 21-aminosteroid U74006F. Journal of vascular surgery, 1993, Volume: 17, Issue:4 Topics: Animals; Drug Evaluation, Preclinical; Ischemia; Kidney; Lipid Peroxides; Male; Nephrectomy; Pregnatrienes; Random Allocation; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Time Factors	1993
Effect of the 21-aminosteroid tirilazad on cerebral pH and somatosensory evoked potentials after incomplete ischemia. Stroke, 1993, Volume: 24, Issue:5 Topics: Acidosis; Adenosine Triphosphate; Animals; Bicarbonates; Brain; Brain Edema; Brain Ischemia; Cytoplasm; Dogs; Drug Evaluation, Preclinical; Evoked Potentials, Somatosensory; Hydrogen-Ion Concentration; Male; Phosphocreatine; Pregnatrienes; Reactive Oxygen Species; Reperfusion Injury	1993
Asphyxial brain damage in the newborn: new insights into pathophysiology and possible pharmacologic interventions. Southern medical journal, 1993, Volume: 86, Issue:6 Topics: Asphyxia Neonatorum; Brain Ischemia; Calcium Channel Blockers; Dizocilpine Maleate; Free Radical Scavengers; Humans; Hypoxia, Brain; Infant, Newborn; Lipid Peroxides; Pregnatrienes; Reperfusion Injury	1993
Effects of an antioxidant in a rabbit model of tourniquet-induced skeletal muscle ischemia-reperfusion injury. The Journal of surgical research, 1996, Volume: 60, Issue:1 Topics: Animals; Antioxidants; Electric Stimulation; Free Radical Scavengers; Ischemia; Isometric Contraction; Male; Muscle, Skeletal; Pregnatrienes; Rabbits; Reperfusion Injury; Tourniquets	1996
Impact of Lazaroid U74006F on ischemia and reperfusion injury of islets after transplantation in the rat. Transplantation proceedings, 1996, Volume: 28, Issue:1 Topics: Animals; Antioxidants; Blood Glucose; Diabetes Mellitus, Experimental; Ischemia; Islets of Langerhans; Islets of Langerhans Transplantation; Organ Preservation; Pregnatrienes; Rats; Reperfusion Injury; Temperature; Time Factors	1996
Tirilazad prevention of reperfusion edema after focal ischemia in cynomolgus monkeys. The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 1996, Volume: 23, Issue:1 Topics: Animals; Antioxidants; Brain Edema; Brain Ischemia; Female; Macaca fascicularis; Magnetic Resonance Imaging; Pregnatrienes; Reperfusion Injury	1996
Effect of endotoxin-enhanced hepatic reperfusion injury on endothelium-dependent relaxation in rat aorta. Shock (Augusta, Ga.), 1996, Volume: 6, Issue:2 Topics: Acetylcholine; Animals; Antioxidants; Aorta, Thoracic; Bacterial Toxins; Constriction; Disease Models, Animal; Endothelium, Vascular; Endotoxins; Ischemia; Lipid Peroxidation; Liver; Male; Multiple Organ Failure; Muscle, Smooth, Vascular; Nitroglycerin; Phenylephrine; Pregnatrienes; Rats; Rats, Inbred F344; Reperfusion Injury; Vasodilation	1996
Comparative study of the effect of 21-aminosteroid and alpha-tocopherol on models of acute oxidative renal injury. Free radical biology & medicine, 1996, Volume: 21, Issue:5 Topics: Animals; Antioxidants; Disease Models, Animal; Free Radical Scavengers; Hydrogen Peroxide; Kidney; Lipid Peroxidation; LLC-PK1 Cells; Male; Pregnatrienes; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Swine; Vitamin E	1996
Lazaroid U74006F for canine small bowel preservation. Transplantation proceedings, 1996, Volume: 28, Issue:5 Topics: alpha-Glucosidases; Animals; Antioxidants; Dogs; Intestine, Small; Malondialdehyde; Organ Preservation; Peroxidase; Pregnatrienes; Reperfusion; Reperfusion Injury; Transplantation, Homologous	1996
Comparison of various lazaroid compounds for protection against ischemic liver injury. Transplantation, 1997, Jan-27, Volume: 63, Issue:2 Topics: Animals; Antioxidants; Dogs; Female; Ischemia; L-Lactate Dehydrogenase; Lipid Peroxidation; Liver; Liver Function Tests; Malondialdehyde; Neovascularization, Pathologic; Pregnatrienes; Reperfusion Injury	1997
Studies of ischemia-reperfusion injury in skeletal muscle: efficacy of 21-aminosteroids on microcirculation and muscle contraction after an extended period of warm ischemia. Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 1997, Volume: 15, Issue:4 Topics: Animals; Antioxidants; Arteries; Arterioles; Contrast Media; Fluorescein; Hot Temperature; Isometric Contraction; Male; Microcirculation; Muscle, Skeletal; Pregnatrienes; Rats; Rats, Sprague-Dawley; Reperfusion Injury	1997
Lazaroid donor pretreatment does not improve lung allograft reperfusion injury in swine. Transplantation proceedings, 1998, Volume: 30, Issue:7 Topics: Animals; Antioxidants; Body Water; Lung Transplantation; Peroxidase; Pregnatrienes; Premedication; Reperfusion Injury; Swine; Thiobarbituric Acid Reactive Substances; Tissue Donors; Transplantation, Homologous	1998
Donor and recipient treatment with the Lazaroid U-74006F do not improve post-transplant lung function in swine. European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 1999, Volume: 15, Issue:4 Topics: Animals; Antioxidants; Disease Models, Animal; Extravascular Lung Water; Free Radical Scavengers; Lung; Lung Transplantation; Postoperative Complications; Pregnatrienes; Pulmonary Edema; Reperfusion Injury; Swine; Transplantation, Homologous	1999
Tirilazad mesylate does not improve early cerebral metabolic recovery following compression ischemia in dogs. Stroke, 1992, Volume: 23, Issue:10 Topics: Animals; Brain Ischemia; Cerebrovascular Circulation; Disease Models, Animal; Dogs; Evoked Potentials, Somatosensory; Injections, Intraventricular; Magnetic Resonance Spectroscopy; Oxygen Consumption; Phosphates; Phosphocreatine; Pregnatrienes; Regional Blood Flow; Reperfusion Injury	1992
Evaluation of intestinal villus height in rats after ischemia and reperfusion by administration of superoxide dismutase, polyethylene glycol-conjugated superoxide dismutase, and two 21-aminosteroids. American journal of veterinary research, 1992, Volume: 53, Issue:11 Topics: Animals; Evaluation Studies as Topic; Free Radical Scavengers; Intestinal Mucosa; Lipid Peroxides; Male; Polyethylene Glycols; Pregnatrienes; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Steroids; Superoxide Dismutase	1992
Tirilazad mesylate protects vitamins C and E in brain ischemia-reperfusion injury. Journal of neurochemistry, 1992, Volume: 58, Issue:6 Topics: Animals; Ascorbic Acid; Brain; Brain Chemistry; Brain Ischemia; Gerbillinae; Lipid Peroxides; Male; Pregnatrienes; Reperfusion Injury; Time Factors; Vitamin E	1992
The protective effects of tirilated mesylate (U74006F) on ischemic and reperfusion-induced cochlear damage. Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 1991, Volume: 105, Issue:4 Topics: Action Potentials; Animals; Cochlea; Cochlear Microphonic Potentials; Free Radicals; Ischemia; Lipid Peroxidation; Lipid Peroxides; Pregnatrienes; Rats; Rats, Inbred Strains; Reperfusion Injury	1991
Effects of a steroidal antioxidant (U74006F) in an acute model of myocardial ischemia/reperfusion injury. Proceedings of the Western Pharmacology Society, 1990, Volume: 33 Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Coronary Disease; Coronary Vessels; Glutathione; Lipid Peroxides; Male; Pregnatrienes; Rabbits; Reperfusion Injury; Thiobarbiturates	1990
Prevention of reperfusion injury in surgically induced gastric dilatation-volvulus in dogs. American journal of veterinary research, 1990, Volume: 51, Issue:2 Topics: Allopurinol; Animals; Dog Diseases; Dogs; Lipid Peroxides; Pregnatrienes; Reperfusion Injury; Stomach Volvulus	1990
Protective effects of a novel 21-aminosteroid during splanchnic artery occlusion shock. Circulatory shock, 1990, Volume: 30, Issue:2 Topics: Animals; Blood Pressure; Cathepsin D; Hematocrit; Male; Mesenteric Vascular Occlusion; Myocardial Depressant Factor; Pregnatrienes; Rats; Rats, Inbred Strains; Reperfusion Injury; Shock	1990