u 74006f has been researched along with Ischemic Attack, Transient in 31 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (16.13) | 18.7374 |
| 1990's | 24 (77.42) | 18.2507 |
| 2000's | 2 (6.45) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Plesnila, N; Schmid-Elsaesser, R; Steiger, HJ; Westermaier, T; Zausinger, S | 1 |
| Plesnila, N; Schmid-Elsaesser, R; Schöller, K; Zausinger, S | 1 |
| Auer, RN | 1 |
| Alves, WM; Haley, EC; Hansen, CA; Kassell, NF; Weir, BK | 1 |
| Asano, T; Matsui, T | 1 |
| Kirsch, JR; Koehler, RC; Takeshima, R; Traystman, RJ | 1 |
| Hall, ED | 1 |
| Oostveen, JA; Williams, LR | 1 |
| Brown, CM; Calder, C; Kenny, BA; Linton, C; Patmore, L; Small, C; Spedding, M | 1 |
| Melon, E; Rimaniol, JM | 1 |
| Hans, P | 1 |
| Alves, WM; Apperson-Hansen, C; Haley, EC; Kassell, NF; Maile, MH | 1 |
| Belmonte, A; del Pilar Fernandez Rodriguez, M; Garcia-Iglesias, E; Garcia-Novio, M; Meizoso, MJ | 1 |
| Baethmann, A; Hungerhuber, E; Reulen, HJ; Schmid-Elsaesser, R; Zausinger, S | 2 |
| Kanamaru, K; Kuroki, M; Miyazawa, T; Sun, H; Suzuki, H; Waga, S | 1 |
| Dorsch, NW | 1 |
| Alves, WM; Brandt, L; Dorsch, NW; Kassell, NF; Lanzino, G; Pasqualin, A; Schmiedek, P; Truskowski, LL | 1 |
| Kassell, NF; Lanzino, G | 1 |
| Bruederlin, B; Buchan, AM; Heinicke, E; Li, H | 1 |
| Buchan, AM; Slivka, A; Xue, D | 1 |
| Hall, ED; Linseman, KL; Pazara, KE | 1 |
| Braughler, JM; Hall, ED; Pazara, KE | 1 |
| Beck, T; Bielenberg, GW | 1 |
| Findlay, JM; Grace, M; Kanamaru, K; Macdonald, RL; Weir, BK | 1 |
| Anderson, DK; Marsch, JT; Schmitt, G; Woodward, J; Zuccarello, M | 1 |
| Braughler, JM; D'Alecy, LG; Hall, ED; Natale, JE; Schott, RJ | 2 |
| Findlay, JM; Grace, M; Krushelnycky, BW; Steinke, DE; Tanabe, T; Weir, BK | 1 |
| Hongo, K; Kassell, NF; Ogawa, H; Tsukahara, T; Vollmer, DG | 1 |
4 review(s) available for u 74006f and Ischemic Attack, Transient
| Article | Year |
|---|---|
Cerebral ischaemia, free radicals and antioxidant protection.
Topics: Animals; Antioxidants; Brain Ischemia; Disease Models, Animal; Free Radical Scavengers; Free Radicals; Ischemic Attack, Transient; Lipid Peroxides; Pregnatrienes; Rats | 1993 |
Tirilazad mesylate attenuates the accumulation of neutrophils in ischemic gerbil brain.
Topics: Animals; Biomarkers; Brain; Cell Survival; Electron Transport Complex IV; Free Radical Scavengers; Gerbillinae; Ischemic Attack, Transient; Neurons; Neutrophils; Pregnatrienes; Reperfusion Injury | 1993 |
[Pharmacological treatment of vasospasm in subarachnoid hemorrhage].
Topics: Antioxidants; Humans; Ischemic Attack, Transient; Lipid Peroxides; Male; Nicardipine; Nimodipine; Papaverine; Plasminogen Activators; Pregnatrienes; Subarachnoid Hemorrhage; Tissue Plasminogen Activator; Vasodilator Agents | 1996 |
The effect and management of delayed vasospasm after aneurysmal subarachnoid hemorrhage.
Topics: Aneurysm, Ruptured; Calcium Channel Blockers; Dose-Response Relationship, Drug; Female; Humans; Ischemic Attack, Transient; Male; Neuroprotective Agents; Nimodipine; Pregnatrienes; Sex Factors; Subarachnoid Hemorrhage; Time Factors | 1998 |
4 trial(s) available for u 74006f and Ischemic Attack, Transient
| Article | Year |
|---|---|
Phase II trial of tirilazad in aneurysmal subarachnoid hemorrhage. A report of the Cooperative Aneurysm Study.
Topics: Adult; Aged; Analysis of Variance; Chi-Square Distribution; Double-Blind Method; Female; Follow-Up Studies; Free Radical Scavengers; Humans; Intracranial Aneurysm; Ischemic Attack, Transient; Lipid Peroxides; Male; Middle Aged; Pregnatrienes; Subarachnoid Hemorrhage | 1995 |
A randomized, double-blind, vehicle-controlled trial of tirilazad mesylate in patients with aneurysmal subarachnoid hemorrhage: a cooperative study in North America.
Topics: Administration, Oral; Anticonvulsants; Calcium Channel Blockers; Cerebral Angiography; Clinical Protocols; Double-Blind Method; Employment; Female; Follow-Up Studies; Glasgow Coma Scale; Humans; Injections, Intravenous; Intracranial Aneurysm; Ischemic Attack, Transient; Male; Middle Aged; Neuroprotective Agents; Nimodipine; North America; Patient Admission; Pharmaceutical Vehicles; Placebos; Pregnatrienes; Prospective Studies; Safety; Sex Factors; Subarachnoid Hemorrhage; Survival Rate; Treatment Outcome | 1997 |
Double-blind, randomized, vehicle-controlled study of high-dose tirilazad mesylate in women with aneurysmal subarachnoid hemorrhage. Part I. A cooperative study in Europe, Australia, New Zealand, and South Africa.
Topics: Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Incidence; International Cooperation; Intracranial Aneurysm; Ischemic Attack, Transient; Middle Aged; Nervous System; Neuroprotective Agents; Pharmaceutical Vehicles; Pregnatrienes; Prospective Studies; Subarachnoid Hemorrhage; Time Factors; Treatment Outcome | 1999 |
Double-blind, randomized, vehicle-controlled study of high-dose tirilazad mesylate in women with aneurysmal subarachnoid hemorrhage. Part II. A cooperative study in North America.
Topics: Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Incidence; Intracranial Aneurysm; Ischemic Attack, Transient; Middle Aged; Nervous System; Neuroprotective Agents; Pharmaceutical Vehicles; Pregnatrienes; Prospective Studies; Subarachnoid Hemorrhage; Time Factors; Treatment Outcome | 1999 |
23 other study(ies) available for u 74006f and Ischemic Attack, Transient
| Article | Year |
|---|---|
Neuroprotection in transient focal cerebral ischemia by combination drug therapy and mild hypothermia: comparison with customary therapeutic regimen.
Topics: Adrenal Cortex Hormones; Animals; Antioxidants; Blood Flow Velocity; Calcium Channel Blockers; Cerebral Infarction; Cerebrovascular Circulation; Dexamethasone; Disease Models, Animal; Drug Therapy, Combination; Hypothermia, Induced; Ischemic Attack, Transient; Magnesium; Male; Mannitol; Methohexital; Neurologic Examination; Neuroprotective Agents; Nimodipine; Pregnatrienes; Rats; Rats, Sprague-Dawley; Recovery of Function; Treatment Outcome | 2003 |
Combination drug therapy and mild hypothermia after transient focal cerebral ischemia in rats.
Topics: Animals; Antioxidants; Blood Flow Velocity; Blood Glucose; Blood Pressure; Cerebral Infarction; Cerebrovascular Circulation; Disease Models, Animal; Drug Therapy, Combination; Hypothermia, Induced; Ischemic Attack, Transient; Laser-Doppler Flowmetry; Magnesium Chloride; Male; Neuroprotective Agents; Pregnatrienes; Rats; Rats, Sprague-Dawley; Survival Rate; Time Factors; Treatment Outcome | 2003 |
Combination therapy with U74006F (tirilazad mesylate), MK-801, insulin and diazepam in transient forebrain ischaemia.
Topics: Animals; Blood Gas Analysis; Blood Glucose; Body Temperature; Cerebral Cortex; Diazepam; Dizocilpine Maleate; Drug Therapy, Combination; Hydrogen-Ion Concentration; Insulin; Ischemic Attack, Transient; Male; Pregnatrienes; Prosencephalon; Rats; Rats, Wistar | 1995 |
Effects of new 21-aminosteroid tirilazad mesylate (U74006F) on chronic cerebral vasospasm in a "two-hemorrhage" model of beagle dogs.
Topics: Animals; Cerebral Angiography; Chronic Disease; Dogs; Dose-Response Relationship, Drug; Female; Free Radical Scavengers; Free Radicals; Infusions, Intravenous; Ischemic Attack, Transient; Lipid Peroxidation; Lipid Peroxides; Male; Pregnatrienes; Subarachnoid Hemorrhage | 1994 |
Tirilazad treatment does not decrease early brain injury after transient focal ischemia in cats.
Topics: Analysis of Variance; Animals; Carotid Arteries; Cats; Cerebrovascular Circulation; Female; Ischemic Attack, Transient; Ligation; Lipid Peroxidation; Pregnatrienes; Random Allocation; Time Factors | 1994 |
New developments in the treatment of SAH-induced cerebral vasospasm.
Topics: Humans; Ischemic Attack, Transient; Lipid Peroxides; Nimodipine; Pregnatrienes; Subarachnoid Hemorrhage | 1993 |
Neuroprotective properties of lifarizine compared with those of other agents in a mouse model of focal cerebral ischaemia.
Topics: Animals; Cerebral Cortex; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Imidazoles; Injections, Intraperitoneal; Ischemic Attack, Transient; Isoquinolines; Mice; Neuroprotective Agents; Nimodipine; Phenytoin; Piperazines; Pregnatrienes; Sodium Channels | 1995 |
[Pharmacological therapeutic prospects of cerebral vasospasm].
Topics: Antioxidants; Fibrinolysis; Humans; Injections, Intraventricular; Ischemic Attack, Transient; Lipid Peroxides; Oxyhemoglobins; Plasminogen Activators; Pregnatrienes; Subarachnoid Hemorrhage; Superoxide Dismutase | 1996 |
Effect of tirilazad on brain nitric oxide synthase activity during cerebral ischemia in rats.
Topics: Animals; Arginine; Brain; Citrulline; Enzyme Inhibitors; Ischemic Attack, Transient; Kinetics; Male; Neuroprotective Agents; Nitric Oxide Synthase; Pregnatrienes; Rats; Rats, Wistar | 1997 |
Monotherapy with dextromethorphan or tirilazad--but not a combination of both--improves outcome after transient focal cerebral ischemia in rats.
Topics: Animals; Calcium Channel Blockers; Cerebral Infarction; Dextromethorphan; Drug Evaluation, Preclinical; Drug Therapy, Combination; Excitatory Amino Acid Antagonists; Ischemic Attack, Transient; Laser-Doppler Flowmetry; Male; Neuroprotective Agents; Pregnatrienes; Rats; Rats, Sprague-Dawley; Treatment Outcome; Weight Gain | 1998 |
Neuroprotective effects of combination therapy with tirilazad and magnesium in rats subjected to reversible focal cerebral ischemia.
Topics: Animals; Cerebral Cortex; Cerebral Infarction; Drug Synergism; Drug Therapy, Combination; Excitatory Amino Acid Antagonists; Free Radical Scavengers; Ischemic Attack, Transient; Laser-Doppler Flowmetry; Magnesium Chloride; Male; Neurologic Examination; Neuroprotective Agents; Pregnatrienes; Rats; Rats, Sprague-Dawley | 1999 |
Effects of tirilazad mesylate on vasospasm and phospholipid hydroperoxides in a primate model of subarachnoid hemorrhage.
Topics: Animals; Cerebral Angiography; Cerebral Arteries; Cerebrovascular Circulation; Chromatography, High Pressure Liquid; Disease Models, Animal; Female; Injections, Intravenous; Ischemic Attack, Transient; Lipid Peroxidation; Luminescent Measurements; Macaca fascicularis; Male; Neuroprotective Agents; Phosphatidylcholines; Phosphatidylethanolamines; Pregnatrienes; Subarachnoid Hemorrhage; Vasoconstriction | 1999 |
Failure of the lipid peroxidation inhibitor, U74006F, to prevent postischemic selective neuronal injury.
Topics: Animals; Cell Death; Cerebral Cortex; Corpus Striatum; Hippocampus; Ischemic Attack, Transient; Lipid Peroxidation; Male; Neurons; Pregnatrienes; Rats; Rats, Inbred Strains | 1992 |
Tirilazad reduces cortical infarction after transient but not permanent focal cerebral ischemia in rats.
Topics: Animals; Brain Ischemia; Cerebral Cortex; Cerebral Infarction; Cerebrovascular Circulation; Ischemic Attack, Transient; Lipid Peroxides; Male; Pregnatrienes; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Reperfusion | 1992 |
Sex differences in postischemic neuronal necrosis in gerbils.
Topics: Animals; Antioxidants; Blood Flow Velocity; Brain; Calcium; Cerebrovascular Circulation; Estradiol; Female; Gerbillinae; Ischemic Attack, Transient; Kinetics; Lipid Peroxidation; Lipid Peroxides; Male; Necrosis; Neurons; Pregnatrienes; Sex Characteristics; Vitamin E | 1991 |
Effects of tirilazad mesylate on postischemic brain lipid peroxidation and recovery of extracellular calcium in gerbils.
Topics: Animals; Brain; Calcium; Gerbillinae; Ischemic Attack, Transient; Kinetics; Lipid Peroxidation; Lipid Peroxides; Male; Pregnatrienes; Reperfusion; Vitamin E | 1991 |
Failure of the lipid peroxidation inhibitor U74006F to improve neurological outcome after transient forebrain ischemia in the rat.
Topics: Animals; Cell Survival; Hippocampus; Ischemic Attack, Transient; Lipid Peroxides; Male; Necrosis; Neurons; Pregnatrienes; Prognosis; Rats; Rats, Inbred Strains | 1990 |
A dosage study of the effect of the 21-aminosteroid U74006F on chronic cerebral vasospasm in a primate model.
Topics: Animals; Chronic Disease; Dose-Response Relationship, Drug; Female; Ischemic Attack, Transient; Macaca fascicularis; Pregnatrienes; Radiography | 1990 |
Effect of the 21-aminosteroid U-74006F on cerebral vasospasm following subarachnoid hemorrhage.
Topics: Animals; Cerebral Angiography; Cerebrovascular Circulation; Ischemic Attack, Transient; Lipid Peroxides; Male; Pregnatrienes; Rabbits; Subarachnoid Hemorrhage; Subtraction Technique | 1989 |
The 21-aminosteroid U74006F reduces systemic lipid peroxidation, improves neurologic function, and reduces mortality after cardiopulmonary arrest in dogs.
Topics: Animals; Dogs; Fatty Acids; Heart Arrest; Ischemic Attack, Transient; Kinetics; Lipid Peroxidation; Lipid Peroxides; Male; Nervous System; Pregnatrienes; Vitamin E | 1989 |
A trial of the 21-aminosteroid U74006F in a primate model of chronic cerebral vasospasm.
Topics: Animals; Biopsy; Brain; Cerebral Angiography; Chromatography, High Pressure Liquid; Double-Blind Method; Female; Ischemic Attack, Transient; Lipid Peroxides; Macaca fascicularis; Pregnatrienes; Random Allocation | 1989 |
Effect of the nonglucocorticoid 21-aminosteroid U74006F experimental cerebral vasospasm.
Topics: Animals; Basilar Artery; Ischemic Attack, Transient; Lipid Peroxides; Male; Pregnatrienes; Rabbits; Subarachnoid Hemorrhage; Vasoconstriction | 1989 |
Effect of the aminosteroid U74006F after cardiopulmonary arrest in dogs.
Topics: Animals; Dogs; Heart Arrest; Ischemic Attack, Transient; Lipid Peroxides; Male; Nervous System Diseases; Osmolar Concentration; Pregnatrienes; Resuscitation; Time Factors; Vitamin E | 1988 |