u 74006f has been researched along with Disease Models, Animal in 34 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 22 (64.71) | 18.2507 |
| 2000's | 9 (26.47) | 29.6817 |
| 2010's | 3 (8.82) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Budohoski, KP; Bulters, DO; Helmy, A; Karri, SK; Kirkpatrick, PJ; Kirollos, RW; Ogilvy, CS; Trivedi, RA; Young, AM | 1 |
| Flessas, II; Papalois, AE; Toutouzas, K; Zagouri, F; Zografos, GC | 1 |
| Arba, F; Balami, JS; Buchan, AM; Kleinschnitz, C; Minnerup, J; Sutherland, BA | 1 |
| Plesnila, N; Schmid-Elsaesser, R; Steiger, HJ; Westermaier, T; Zausinger, S | 1 |
| Plesnila, N; Schmid-Elsaesser, R; Schöller, K; Zausinger, S | 1 |
| Chmiel, B; Cierpka, L; Grabowska-Bochenek, R; Pajak, J | 1 |
| Gahm, C; Holmin, S; Mathiesen, T; Rudehill, S | 1 |
| Cibula, C; Coleman, ML; Crisp, T; Finnerty, EP; Giles, JR; Minus, TO | 1 |
| Macleod, M; Sandercock, P; Sena, E; Wheble, P | 1 |
| Abad-Hernández, MM; Broseta-Rodrigo, J; García-March, G; Gonçalves-Estella, JM; Sánchez-Casado, M; Sánchez-Ledesma, MJ | 1 |
| Ettinger, SL; Keown, PA; Scudamore, CH; Shackleton, CR; Toleikis, PF | 1 |
| Clark, WM; Coull, BM; Hotan, T; Lauten, JD | 1 |
| Beattie, MS; Behrmann, DL; Bresnahan, JC | 1 |
| Cosenza, CA; Cramer, DV; Cunneen, SA; Makowka, L; Tuso, PJ; Wang, HK | 1 |
| Hall, ED | 2 |
| Brown, CM; Calder, C; Kenny, BA; Linton, C; Patmore, L; Small, C; Spedding, M | 1 |
| Bernstein, M; Cabantog, AM; Glen, J; Mikulis, D; Stiver, S | 1 |
| Jaeschke, H; Laskey, RE; Mathews, WR; McKenna, R; Wang, Y | 1 |
| Andiné, P; Bågenholm, R; Hagberg, H | 1 |
| Kanji, VK; Salahudeen, AK; Wang, C | 1 |
| Dijkstra, CD; Polman, CH; Sontrop, K; Uitdehaag, BM | 1 |
| Bednar, MM; Booth, C; Gross, CE; Kimelberg, HK; Raymond-Russell, S | 1 |
| Hall, ED; Jolly, RA; Oostveen, JA; Petry, TW; Satoh, PS; Williams, LR | 1 |
| Andrus, PK; Gleason, DD; Hall, ED; Smith, SL | 1 |
| Hall, ED; Smith, SL | 1 |
| Kanamaru, K; Kuroki, M; Miyazawa, T; Sun, H; Suzuki, H; Waga, S | 1 |
| Boehler, A; Hillinger, S; Schmid, RA; Schöb, OM; Stammberger, U; Weder, W; Zollinger, A | 1 |
| Amari, T; Fujimoto, K; Hanaoka, M; Hayano, T; Kaneki, T; Kobayashi, T; Koizumi, T; Koyama, S; Kubo, K; Miyahara, T | 1 |
| Akdemir, H; Koç, RK; Kontaş, O; Kurtsoy, A; Menkü, A; Oktem, IS | 1 |
| Earl, CD; Höglinger, GU; Oertel, WH; Sautter, J | 1 |
| Blizzard, KK; Helfaer, MA; Hurn, PD; Kirsch, JR; Koehler, RC; Traystman, RJ | 1 |
| Becker, DP; Black, KL; Conklin, S; Ikezaki, K; King, WA | 1 |
| Dikdan, GS; Machiedo, GW; Powell, RJ; Rush, BF | 1 |
4 review(s) available for u 74006f and Disease Models, Animal
| Article | Year |
|---|---|
Effects of lazaroids on intestinal ischemia and reperfusion injury in experimental models.
Topics: Animals; Antioxidants; Disease Models, Animal; Intestinal Mucosa; Intestines; Pregnatrienes; Reperfusion Injury | 2011 |
Neuroprotection for ischaemic stroke: translation from the bench to the bedside.
Topics: Acute Disease; Animals; Benzenesulfonates; Brain Ischemia; Chelating Agents; Clinical Trials as Topic; Combined Modality Therapy; Diffusion of Innovation; Disease Models, Animal; Drug Evaluation, Preclinical; Egtazic Acid; Hematopoietic Cell Growth Factors; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypothermia, Induced; Magnesium; Minocycline; NADPH Oxidases; Neuroprotective Agents; Pregnatrienes; Serum Albumin; Stroke; Thrombolytic Therapy; Translational Research, Biomedical | 2012 |
Systematic review and meta-analysis of the efficacy of tirilazad in experimental stroke.
Topics: Animals; Disease Models, Animal; Humans; Pregnatrienes; Stroke | 2007 |
Cerebral ischaemia, free radicals and antioxidant protection.
Topics: Animals; Antioxidants; Brain Ischemia; Disease Models, Animal; Free Radical Scavengers; Free Radicals; Ischemic Attack, Transient; Lipid Peroxides; Pregnatrienes; Rats | 1993 |
30 other study(ies) available for u 74006f and Disease Models, Animal
| Article | Year |
|---|---|
Pharmacologic Management of Subarachnoid Hemorrhage.
Topics: Adrenal Cortex Hormones; Animals; Anticoagulants; Apoptosis; Brain Ischemia; Calcium Channel Blockers; Clinical Trials as Topic; Dexamethasone; Dioxanes; Disease Models, Animal; Drugs, Chinese Herbal; Estrogens; Evidence-Based Medicine; Free Radical Scavengers; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Magnesium Sulfate; Neuroprotective Agents; Nimodipine; Platelet Aggregation Inhibitors; Pregnatrienes; Progesterone; Pyridines; Pyrimidines; Receptor, Endothelin A; Subarachnoid Hemorrhage; Sulfonamides; Tetrazoles | 2015 |
Neuroprotection in transient focal cerebral ischemia by combination drug therapy and mild hypothermia: comparison with customary therapeutic regimen.
Topics: Adrenal Cortex Hormones; Animals; Antioxidants; Blood Flow Velocity; Calcium Channel Blockers; Cerebral Infarction; Cerebrovascular Circulation; Dexamethasone; Disease Models, Animal; Drug Therapy, Combination; Hypothermia, Induced; Ischemic Attack, Transient; Magnesium; Male; Mannitol; Methohexital; Neurologic Examination; Neuroprotective Agents; Nimodipine; Pregnatrienes; Rats; Rats, Sprague-Dawley; Recovery of Function; Treatment Outcome | 2003 |
Combination drug therapy and mild hypothermia after transient focal cerebral ischemia in rats.
Topics: Animals; Antioxidants; Blood Flow Velocity; Blood Glucose; Blood Pressure; Cerebral Infarction; Cerebrovascular Circulation; Disease Models, Animal; Drug Therapy, Combination; Hypothermia, Induced; Ischemic Attack, Transient; Laser-Doppler Flowmetry; Magnesium Chloride; Male; Neuroprotective Agents; Pregnatrienes; Rats; Rats, Sprague-Dawley; Survival Rate; Time Factors; Treatment Outcome | 2003 |
Decreased red blood cells deformability in acute pancreatitis in the rat. Effect of tirilazad mesylate.
Topics: Acute Disease; Animals; Antioxidants; Disease Models, Animal; Erythrocyte Deformability; Free Radical Scavengers; Leukocyte Count; Lipid Peroxidation; Male; Pancreatitis; Pregnatrienes; Random Allocation; Rats; Rats, Sprague-Dawley; Regression Analysis; Time Factors | 2003 |
Neuronal degeneration and iNOS expression in experimental brain contusion following treatment with colchicine, dexamethasone, tirilazad mesylate and nimodipine.
Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Brain; Brain Injuries; Calcium Channel Blockers; Cell Survival; Colchicine; Dexamethasone; Disease Models, Animal; Encephalitis; Fluoresceins; Free Radical Scavengers; In Situ Nick-End Labeling; Male; Nerve Degeneration; Neuroprotective Agents; Nimodipine; Nitric Oxide; Nitric Oxide Synthase Type II; Organic Chemicals; Oxidative Stress; Pregnatrienes; Rats; Rats, Sprague-Dawley | 2005 |
Aging, peripheral nerve injury and nociception: effects of the antioxidant 16-desmethyltirilazad.
Topics: Aging; Analysis of Variance; Animals; Antioxidants; Disease Models, Animal; Pain; Pain Measurement; Peripheral Nervous System Diseases; Pregnatrienes; Rats; Rats, Inbred F344; Time Factors | 2006 |
[Effect of combination therapy with hypothermia, magnesium and tirilazad in an experimental model of diffuse cerebral ischemia].
Topics: Animals; Brain Ischemia; Combined Modality Therapy; Disease Models, Animal; Hypothermia, Induced; Magnesium; Male; Neuroprotective Agents; Pregnatrienes; Rats; Rats, Wistar | 2007 |
Effect of a 21-aminosteroid, U74006F, on lipid peroxidation and glomerulotubular function following experimental renal ischemia.
Topics: Animals; Creatinine; Disease Models, Animal; Glomerular Filtration Rate; Kidney; Kidney Tubules; Lipid Peroxidation; Pregnatrienes; Random Allocation; Rats; Reperfusion Injury; Sodium; Superoxide Dismutase; Time Factors | 1994 |
Therapeutic efficacy of tirilazad in experimental multiple cerebral emboli: a randomized, controlled trial.
Topics: Animals; Brain Ischemia; Cell Adhesion; Disease Models, Animal; Drug Evaluation, Preclinical; Free Radical Scavengers; Intracranial Embolism and Thrombosis; Lipid Peroxides; Male; Microspheres; Neutrophils; Pregnatrienes; Rabbits; Random Allocation | 1994 |
Modeling of acute spinal cord injury in the rat: neuroprotection and enhanced recovery with methylprednisolone, U-74006F and YM-14673.
Topics: Animals; Azetidines; Dipeptides; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Hindlimb; Lipid Peroxides; Locomotion; Methylprednisolone; Motor Activity; Pregnatrienes; Rats; Rats, Sprague-Dawley; Spinal Cord; Spinal Cord Injuries; Thyrotropin-Releasing Hormone | 1994 |
Protective effect of the lazaroid U74006F in cold ischemia-reperfusion injury of the liver.
Topics: Animals; Cell Survival; Cells, Cultured; Cold Temperature; Disease Models, Animal; Endothelium, Vascular; Female; Free Radical Scavengers; Graft Survival; Lipid Peroxides; Liver; Liver Transplantation; Male; Organ Culture Techniques; Organ Preservation; Pregnatrienes; Random Allocation; Rats; Rats, Inbred Lew; Reperfusion Injury; Swine; Swine, Miniature | 1994 |
The role of oxygen radicals in traumatic injury: clinical implications.
Topics: Animals; Antioxidants; Blood-Brain Barrier; Brain Edema; Brain Injuries; Brain Ischemia; Cell Death; Disease Models, Animal; Free Radicals; Humans; Lipid Peroxidation; Lipid Peroxides; Mice; Pregnatrienes; Reactive Oxygen Species; Spinal Cord Injuries | 1993 |
Neuroprotective properties of lifarizine compared with those of other agents in a mouse model of focal cerebral ischaemia.
Topics: Animals; Cerebral Cortex; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Imidazoles; Injections, Intraperitoneal; Ischemic Attack, Transient; Isoquinolines; Mice; Neuroprotective Agents; Nimodipine; Phenytoin; Piperazines; Pregnatrienes; Sodium Channels | 1995 |
Tirilazad does not protect rat brain from brachytherapy-induced injury.
Topics: Animals; Antioxidants; Brachytherapy; Brain; Brain Injuries; Disease Models, Animal; Magnetic Resonance Imaging; Male; Pregnatrienes; Rats; Rats, Inbred F344; Time Factors | 1996 |
Effect of endotoxin-enhanced hepatic reperfusion injury on endothelium-dependent relaxation in rat aorta.
Topics: Acetylcholine; Animals; Antioxidants; Aorta, Thoracic; Bacterial Toxins; Constriction; Disease Models, Animal; Endothelium, Vascular; Endotoxins; Ischemia; Lipid Peroxidation; Liver; Male; Multiple Organ Failure; Muscle, Smooth, Vascular; Nitroglycerin; Phenylephrine; Pregnatrienes; Rats; Rats, Inbred F344; Reperfusion Injury; Vasodilation | 1996 |
Effects of the 21-amino steroid tirilazad mesylate (U-74006F) on brain damage and edema after perinatal hypoxia-ischemia in the rat.
Topics: Animals; Antioxidants; Body Weight; Brain Damage, Chronic; Brain Edema; Brain Ischemia; Disease Models, Animal; Drug Evaluation, Preclinical; Free Radical Scavengers; Hypoxia, Brain; Neuroprotective Agents; Pregnatrienes; Rats; Rats, Inbred WF; Rats, Sprague-Dawley; Statistics as Topic | 1996 |
Comparative study of the effect of 21-aminosteroid and alpha-tocopherol on models of acute oxidative renal injury.
Topics: Animals; Antioxidants; Disease Models, Animal; Free Radical Scavengers; Hydrogen Peroxide; Kidney; Lipid Peroxidation; LLC-PK1 Cells; Male; Pregnatrienes; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Swine; Vitamin E | 1996 |
The effect of the 21-aminosteroid U74006F on the clinical course of acute experimental allergic encephalomyelitis.
Topics: Acute Disease; Animals; Anti-Inflammatory Agents; Antioxidants; Disease Models, Animal; Dose-Response Relationship, Drug; Encephalomyelitis, Autoimmune, Experimental; Male; Methylprednisolone; Pregnatrienes; Rats; Rats, Inbred Lew | 1996 |
Delayed adjuvant therapy with the 21-aminosteroid U74006F and the anion channel blocker L644-711 does not improve outcome following thrombolytic therapy in a rabbit model of thromboembolic stroke.
Topics: Animals; Anions; Biological Transport; Cerebrovascular Circulation; Cerebrovascular Disorders; Chemotherapy, Adjuvant; Disease Models, Animal; Female; Fluorenes; Male; Neuroprotective Agents; Pregnatrienes; Rabbits; Thromboembolism; Thrombolytic Therapy; Time Factors; Treatment Outcome | 1997 |
Cyclophosphamide is neuroprotective in a gerbil model of transient severe focal cerebral ischemia: correlation with effects of tirilazad mesylate (U-74006F).
Topics: Animals; Brain Ischemia; Cyclophosphamide; Disease Models, Animal; Gerbillinae; Male; Neuroprotective Agents; Pregnatrienes | 1996 |
Infant rat model of the shaken baby syndrome: preliminary characterization and evidence for the role of free radicals in cortical hemorrhaging and progressive neuronal degeneration.
Topics: Age Factors; Animals; Battered Child Syndrome; Brain Chemistry; Cerebral Hemorrhage; Disease Models, Animal; Free Radical Scavengers; Free Radicals; Head Injuries, Closed; Humans; Hydroxyl Radical; Hypoxia; Infant; Lipid Peroxidation; Male; Nerve Degeneration; Pregnatrienes; Rats; Rats, Sprague-Dawley; Vitamin E | 1998 |
Tirilazad widens the therapeutic window for riluzole-induced attenuation of progressive cortical degeneration in an infant rat model of the shaken baby syndrome.
Topics: Age Factors; Animals; Battered Child Syndrome; Body Temperature; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Free Radical Scavengers; Glutamic Acid; Head Injuries, Closed; Humans; Hypoxia; Infant; Lipid Peroxidation; Male; Nerve Degeneration; Neuroprotective Agents; Pregnatrienes; Pyrimidines; Pyrroles; Rats; Rats, Sprague-Dawley; Riluzole; Time Factors | 1998 |
Effects of tirilazad mesylate on vasospasm and phospholipid hydroperoxides in a primate model of subarachnoid hemorrhage.
Topics: Animals; Cerebral Angiography; Cerebral Arteries; Cerebrovascular Circulation; Chromatography, High Pressure Liquid; Disease Models, Animal; Female; Injections, Intravenous; Ischemic Attack, Transient; Lipid Peroxidation; Luminescent Measurements; Macaca fascicularis; Male; Neuroprotective Agents; Phosphatidylcholines; Phosphatidylethanolamines; Pregnatrienes; Subarachnoid Hemorrhage; Vasoconstriction | 1999 |
Donor and recipient treatment with the Lazaroid U-74006F do not improve post-transplant lung function in swine.
Topics: Animals; Antioxidants; Disease Models, Animal; Extravascular Lung Water; Free Radical Scavengers; Lung; Lung Transplantation; Postoperative Complications; Pregnatrienes; Pulmonary Edema; Reperfusion Injury; Swine; Transplantation, Homologous | 1999 |
A 21-aminosteroid, U-74006F, attenuates endotoxin-induced lung injury in awake sheep.
Topics: 6-Ketoprostaglandin F1 alpha; Animals; Antioxidants; Blood Gas Analysis; Disease Models, Animal; Drug Evaluation, Preclinical; Escherichia coli; Hemodynamics; Leukocyte Count; Lipopolysaccharides; Lymph; Pregnatrienes; Pulmonary Circulation; Respiratory Distress Syndrome; Sheep; Thromboxane B2; Wakefulness | 1999 |
Therapeutic effect of tirilazad mesylate (U-74006F), mannitol, and their combination on experimental ischemia.
Topics: Animals; Brain Ischemia; Disease Models, Animal; Diuretics, Osmotic; Drug Therapy, Combination; Mannitol; Neuroprotective Agents; Photomicrography; Pregnatrienes; Rabbits; Random Allocation; Statistics, Nonparametric | 2000 |
Systemic treatment with GM1 ganglioside improves survival and function of cryopreserved embryonic midbrain grafted to the 6-hydroxydopamine-lesioned rat striatum.
Topics: Animals; Brain Tissue Transplantation; Cell Count; Cell Survival; Corpus Striatum; Cryopreservation; Disease Models, Animal; Female; Fetal Tissue Transplantation; G(M1) Ganglioside; Graft Survival; Mesencephalon; Motor Activity; Neurons; Neuroprotective Agents; Oxidopamine; Parkinson Disease, Secondary; Pregnatrienes; Rats; Rats, Sprague-Dawley; Recovery of Function; Tyrosine 3-Monooxygenase | 2000 |
Tirilazad mesylate does not improve early cerebral metabolic recovery following compression ischemia in dogs.
Topics: Animals; Brain Ischemia; Cerebrovascular Circulation; Disease Models, Animal; Dogs; Evoked Potentials, Somatosensory; Injections, Intraventricular; Magnetic Resonance Spectroscopy; Oxygen Consumption; Phosphates; Phosphocreatine; Pregnatrienes; Regional Blood Flow; Reperfusion Injury | 1992 |
Tumor-associated neurological dysfunction prevented by lazaroids in rats.
Topics: Animals; Brain Neoplasms; Capillary Permeability; Carcinoma 256, Walker; Chromans; Disease Models, Animal; Lipid Peroxides; Nervous System Diseases; Piperazines; Pregnatrienes; Rats | 1991 |
Effect of oxygen-free radical scavengers on survival in sepsis.
Topics: Animals; Chromans; Disease Models, Animal; Free Radical Scavengers; Male; Peritonitis; Piperazines; Pregnatrienes; Premedication; Rats; Rats, Inbred Strains; Sepsis; Survival Rate; Vitamin E | 1991 |