u-44069 has been researched along with Cocarcinogenesis* in 1 studies
1 other study(ies) available for u-44069 and Cocarcinogenesis
Article | Year |
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Tumorigenic potential of endoperoxide analogs.
The endoperoxide analogs known as U-46619 and U-44069 significantly enhanced the carcinoma formation and cellular atypicality initiated by a chemical carcinogen in mice. Studies of DNA radioactivity demonstrated that endoperoxides exerted their cocarcinogenic action by stimulating DNA synthesis. Thus, they play an important role in tumor cell proliferation. Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Cocarcinogenesis; DNA Replication; Male; Methylcholanthrene; Mice; Microscopy, Electron; Prostaglandin Endoperoxides, Synthetic | 1984 |