Page last updated: 2024-10-22

tyrphostin a23 and Sarcoma, Synovial

tyrphostin a23 has been researched along with Sarcoma, Synovial in 1 studies

tyrphostin A23: inhibits EGF-stimulated thymidine incorporation as well as EGF-stimulated receptor autophosphorylation & tyrosine phosphorylation & cell proliferation; structure given in first source

Sarcoma, Synovial: A malignant neoplasm arising from tenosynovial tissue of the joints and in synovial cells of tendons and bursae. The legs are the most common site, but the tumor can occur in the abdominal wall and other trunk muscles. There are two recognized types: the monophasic (characterized by sheaths of monotonous spindle cells) and the biphasic (characterized by slit-like spaces or clefts within the tumor, lined by cuboidal or tall columnar epithelial cells). These sarcomas occur most commonly in the second and fourth decades of life. (From Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1363)

Research Excerpts

ExcerptRelevanceReference
"Synovial sarcoma is a soft tissue cancer associated with a recurrent t(X:18) translocation that generates one of two fusion proteins, SYT-SSX1 or SYT-SSX2."1.34The synovial sarcoma SYT-SSX2 oncogene remodels the cytoskeleton through activation of the ephrin pathway. ( Barco, R; Benesh, A; Caldwell, RL; Eid, JE; Frump, AL; Garcia, CB; Hunt, LB, 2007)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Barco, R1
Hunt, LB1
Frump, AL1
Garcia, CB1
Benesh, A1
Caldwell, RL1
Eid, JE1

Other Studies

1 other study available for tyrphostin a23 and Sarcoma, Synovial

ArticleYear
The synovial sarcoma SYT-SSX2 oncogene remodels the cytoskeleton through activation of the ephrin pathway.
    Molecular biology of the cell, 2007, Volume: 18, Issue:10

    Topics: Animals; Cell Proliferation; Cell Shape; Cytoskeleton; Enzyme Activation; Ephrins; Gene Expression R

2007