tyrphostin 25 has been researched along with Brain Neoplasms in 3 studies
Brain Neoplasms: Neoplasms of the intracranial components of the central nervous system, including the cerebral hemispheres, basal ganglia, hypothalamus, thalamus, brain stem, and cerebellum. Brain neoplasms are subdivided into primary (originating from brain tissue) and secondary (i.e., metastatic) forms. Primary neoplasms are subdivided into benign and malignant forms. In general, brain tumors may also be classified by age of onset, histologic type, or presenting location in the brain.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cocultures of human glioblastoma spheroids (derived from three separate patients) and fetal rat brain aggregates were examined for infiltration using confocal microscopy, in the presence of 0 to 100 mumol/L genistein, a tyrosine kinase (TK) inhibitor, and 3 mumol/L tyrphostin A25, a specific EGFR-TK inhibitor." | 3.69 | Inhibition of epidermal growth factor receptor-associated tyrosine kinase blocks glioblastoma invasion of the brain. ( Bhushan, A; Khoshyomn, S; Penar, PL; Tritton, TR, 1997) |
| " However, dose-response curves revealed significant differences in the IC50 values obtained for some TYRs (T25 and T56), and significant differences in the IC50 potency rank order when comparing inhibition of LPS versus cytokine-dependent iNOS induction." | 1.29 | Differential suppression of glial nitric oxide synthase induction by structurally related tyrosine kinase inhibitors. ( Feinstein, DL; Galea, E; Reddi, J, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Penar, PL | 1 |
| Khoshyomn, S | 1 |
| Bhushan, A | 1 |
| Tritton, TR | 1 |
| Galea, E | 1 |
| Reddi, J | 1 |
| Feinstein, DL | 1 |
| Mullapudi, SR | 1 |
| Ali-Osman, F | 1 |
| Shou, J | 1 |
| Srivenugopal, KS | 1 |
3 other studies available for tyrphostin 25 and Brain Neoplasms
| Article | Year |
|---|---|
Inhibition of epidermal growth factor receptor-associated tyrosine kinase blocks glioblastoma invasion of the brain.
Topics: Animals; Brain; Brain Neoplasms; Cell Division; Cell Movement; Dose-Response Relationship, Drug; Enz | 1997 |
Differential suppression of glial nitric oxide synthase induction by structurally related tyrosine kinase inhibitors.
Topics: Animals; Brain Neoplasms; Cytokines; Enzyme Induction; Enzyme Inhibitors; Gene Expression; Glioma; I | 1995 |
DNA repair protein O6-alkylguanine-DNA alkyltransferase is phosphorylated by two distinct and novel protein kinases in human brain tumour cells.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Animals; Brain Neoplasms; Calcium-Calmodulin-Dependent | 2000 |