tyrosine and Pancreatic Neoplasms

tyrosine has been researched along with Pancreatic Neoplasms in 51 studies

Research

Studies (51)

TimeframeStudies, this research(%)All Research%
pre-19906 (11.76)18.7374
1990's13 (25.49)18.2507
2000's16 (31.37)29.6817
2010's12 (23.53)24.3611
2020's4 (7.84)2.80

Authors

AuthorsStudies
Ali, DW; Chen, XZ; Deng, X; Dong, X; Hu, M; Huang, H; Huang, Y; Li, S; Liu, N; Liu, S; Luo, S; Lyu, H; Michalak, M; Tang, J; Tang, Y; Wang, M; Wang, Z; Xiao, S; Zhang, R; Zhang, X; Zhou, C; Zhu, X1
Cai, X; Li, S; Singhi, AD; Tang, D; Wang, Z; Xie, W; Xu, M; Yang, D; Yates, NA; Zeng, X1
Pasca di Magliano, M; Zhang, Y1
Aoki, M; Hatazawa, J; Horitsugi, G; Ikeda, H; Kanai, Y; Kongpracha, P; Nagamori, S; Naka, S; Shimosegawa, E; Watabe, T1
Inohara, H; Jin, C; Kanai, Y; Liu, X; Miyabe, J; Nagamori, S; Ohgaki, R; Ohki, H; Okuda, S; Quan, L; Saito, K; Wei, L; Yoshino, K1
Han, J; Huang, Y; Jin, H; Liu, P; Liu, X; Meng, X; Tan, X; Wu, Y; Yu, B1
Reubi, JC; Waser, B1
Acoba, J; Furuya, H; Paladino, D; Rosser, CJ; Turkson, J; Yue, P1
Fujii, H; Kusama, T; Okamoto, H1
Abe, M; Akiba, J; Ikezono, Y; Iwamoto, H; Koga, H; Masuda, A; Nakamura, T; Sakaue, T; Torimura, T; Tsuruta, O; Wada, F; Yano, H; Yoshida, T1
Cao, L; Freeman, JW; Jin, C; Lazor, JW; Sperry, J; Venkatasubbarao, K; Zhao, S1
Buck, AK; Eckel, F; Friess, H; Herrmann, K; Kleeff, J; Krause, BJ; Scheidhauer, K; Schmid, RM; Schmidt, S; Schuster, T; Schwaiger, M; Wester, HJ1
Aulak, KS; Corbett, JA; Crabb, JW; Koeck, T; Stuehr, DJ1
Farago, M; Katzav, S; Lazer, G; Machida, K; Mayer, BJ; Pe'er, L1
Fujii, S; Hiraoka, N; Kanai, Y; Kosuge, T; Miyazawa, Y; Nojima, Y; Sakai, R; Uekita, T1
Bajaj, E; Besmer, D; Gendler, SJ; Hwang, SI; Lee, YY; Mukherjee, P; Nath, S; Roy, LD; Sahraei, M; Shanmugam, K; Subramani, DB; Tinder, TL1
Anders, RA; Edil, BH; Foley, K; Huang, L; Illei, PB; Jaffee, EM; Laheru, D; Le, DT; Leubner, A; Maitra, A; Mizuma, M; Mo, G; Olino, K; Sharma, R; Van Eyk, JE; Zheng, L1
Etoh, H; Hosokawa, M; Kato, H; Kato, K; Maejima, Y; Maoka, T; Matsumoto, G; Miyashita, K; Mori, H; Nakatugawa, H; Suzuki, N; Tokuda, H; Tsuboi, M1
Delle Fave, G; Di Florio, A; Jensen, RT; Moreno, P; Sancho, V1
Brattain, MG; DeArmond, D; Freeman, JW; Jessup, JM; Kreisberg, J; Malik, S; Zhao, S1
Ashley, SW; Duxbury, MS; Ito, H; Whang, EE; Zinner, MJ1
Fidler, IJ; Yokoi, K1
Bhagroo, NV; Brelje, TC; Sorenson, RL; Stout, LE1
Cao, P; Gronda, M; Hedley, DW; Jacobberger, JW; Pham, NA; Schimmer, AD1
Choudary, A; Freeman, JW; Venkatasubbarao, K1
Dufresne, M; Estève, JP; Ferrand, A; Fourmy, D; Kowalski-Chauvel, A; Lopez, F; Seva, C; Vatinel, S1
Cerny, RL; Gendler, SJ; Hollingsworth, MA; Kazlauskas, A; Shanmugam, K; Singh, PK; Swanson, BJ; Wen, Y1
Billadeau, DD; Bramati, P; Chatterjee, S; Hedin, K; Shah, V; Sreekumar, R; Urrutia, R1
Hill, MJ1
Bayna, EM; Cheresh, DA; Klemke, RL; Yebra, M1
Dye, JF; Gillespie, J; Guillou, PJ; Schachter, M1
Akedo, H; Imamura, F; Isoai, A; Kitagawa, I; Kobayashi, M; Mukai, M; Shinkai, K1
Büchler, MW; Cao, T; Fan, HU; Hope, C; Kobrin, MS; Korc, M; Lopez, ME; van Nostrand, K; Wagner, M1
Brooks, PC; Cheresh, DA; Klemke, RL; Leng, J; Molander, R; Vuori, K1
Ashford, ML; Harvey, J1
Adler, G; Flossmann-Kast, BB; Hoeflich, A; Jehle, PM; Lutz, MP1
Ellis, C; Green, M; MacMillan-Crow, LA; Thompson, JA; Vickers, SM1
Barazzoni, R; Tessari, P; Tiengo, A; Zanetti, M1
Greendorfer, JS; MacMillan-Crow, LA; Thompson, JA; Vickers, SM1
Benali, N; Buscail, L; Calise, D; Cordelier, P; Esteve, JP; Nagy, A; Pages, P; Pour, PM; Rochaix, P; Schally, AV; Susini, C; Vaysse, N1
Adrian, TE; Ding, XZ; Tong, WG1
El-Hariry, I; Lemoine, NR; Pignatelli, M1
Payne, RB; Salway, JG1
Arvanitakis, C; Greenberger, NJ1
Kamer, AR; Lee, MT; Liebow, C; Schally, AV1
Chandrasekar, B; Korc, M; Shah, GN1
Bakker, WH; Krenning, EP; Lamberts, SW; Reubi, JC1
Hirai, M; Kobayashi, M; Shimizu, N1
Ewen, SW; Pearse, AG; Polak, JM1
Godal, HC; Kierulf, P1
Arkhipenko, VI; Spitsa, AI1

Reviews

1 review(s) available for tyrosine and Pancreatic Neoplasms

ArticleYear
Bacterial metabolism and human carcinogenesis.
    British medical bulletin, 1980, Volume: 36, Issue:1

    Topics: Bacteria; Bile Acids and Salts; Biliary Tract Neoplasms; Cholesterol; Female; Gastrointestinal Neoplasms; Humans; Neoplasms; Nitrosamines; Nitroso Compounds; Pancreatic Neoplasms; Phenols; Schistosomiasis; Tryptophan; Tyrosine; Urinary Bladder Neoplasms; Uterine Cervical Neoplasms

1980

Other Studies

50 other study(ies) available for tyrosine and Pancreatic Neoplasms

ArticleYear
B-lymphoid tyrosine kinase-mediated FAM83A phosphorylation elevates pancreatic tumorigenesis through interacting with β-catenin.
    Signal transduction and targeted therapy, 2023, 02-17, Volume: 8, Issue:1

    Topics: beta Catenin; Carcinogenesis; Cell Transformation, Neoplastic; Humans; Neoplasm Proteins; Pancreatic Neoplasms; Phosphorylation; src-Family Kinases; Tyrosine; Wnt Signaling Pathway

2023
Inhibition of the SLC35B2-TPST2 Axis of Tyrosine Sulfation Attenuates the Growth and Metastasis of Pancreatic Ductal Adenocarcinom.
    Cellular and molecular gastroenterology and hepatology, 2023, Volume: 16, Issue:3

    Topics: Animals; Carcinoma, Pancreatic Ductal; Humans; Integrin beta4; Membrane Proteins; Mice; Pancreatic Neoplasms; Sulfate Transporters; Sulfotransferases; Tyrosine

2023
Tyrosine Sulfation: A New Player and Potential Target in Pancreatic Cancer.
    Cellular and molecular gastroenterology and hepatology, 2023, Volume: 16, Issue:3

    Topics: Amino Acid Sequence; Humans; Pancreatic Neoplasms; Tyrosine

2023
Distribution of LAT1-targeting PET tracer was independent of the tumor blood flow in rat xenograft models of C6 glioma and MIA PaCa-2.
    Annals of nuclear medicine, 2019, Volume: 33, Issue:6

    Topics: Animals; Blood Circulation; Boron Compounds; Cell Line, Tumor; Cell Transformation, Neoplastic; Glioma; Humans; Large Neutral Amino Acid-Transporter 1; Male; Pancreatic Neoplasms; Phenylalanine; Positron-Emission Tomography; Radioactive Tracers; Radiopharmaceuticals; Rats; Tissue Distribution; Tyrosine

2019
Boron delivery for boron neutron capture therapy targeting a cancer-upregulated oligopeptide transporter.
    Journal of pharmacological sciences, 2019, Volume: 139, Issue:3

    Topics: Animals; Biological Transport; Boron Compounds; Boron Neutron Capture Therapy; Cell Line, Tumor; Female; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Pancreatic Neoplasms; Peptide Transporter 1; Phenylalanine; Symporters; Tyrosine; Up-Regulation; Xenograft Model Antitumor Assays

2019
Integrin beta 4 (ITGB4) and its tyrosine-1510 phosphorylation promote pancreatic tumorigenesis and regulate the MEK1-ERK1/2 signaling pathway.
    Bosnian journal of basic medical sciences, 2020, Feb-05, Volume: 20, Issue:1

    Topics: Carcinogenesis; Cell Movement; Humans; Integrin beta4; MAP Kinase Signaling System; Neoplasm Invasiveness; Pancreatic Neoplasms; Phosphorylation; Tyrosine

2020
Triple-peptide receptor targeting in vitro allows detection of all tested gut and bronchial NETs.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2015, Volume: 56, Issue:4

    Topics: Autoradiography; Bronchial Neoplasms; Glucagon-Like Peptide-1 Receptor; Humans; Insulinoma; Iodine Radioisotopes; Ligands; Neoplasm Metastasis; Neuroendocrine Tumors; Octreotide; Pancreatic Neoplasms; Protein Binding; Receptors, Gastrointestinal Hormone; Receptors, Glucagon; Receptors, Peptide; Receptors, Somatostatin; Tyrosine

2015
A novel nuclear Src and p300 signaling axis controls migratory and invasive behavior in pancreatic cancer.
    Oncotarget, 2016, Feb-09, Volume: 7, Issue:6

    Topics: Animals; Apoptosis; Blotting, Western; Carcinoma, Pancreatic Ductal; Cell Movement; Cell Nucleus; Cell Proliferation; Cells, Cultured; Chromatin Immunoprecipitation; E1A-Associated p300 Protein; Embryo, Mammalian; Fibroblasts; Fluorescent Antibody Technique; Humans; Immunoenzyme Techniques; Immunoprecipitation; Mice; Neoplasm Invasiveness; Pancreatic Neoplasms; Phosphorylation; Proto-Oncogene Proteins pp60(c-src); Signal Transduction; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tyrosine; Wound Healing

2016
Tyrosine Phosphorylation of Focal Adhesion Anchoring Proteins Enhances Human Pancreatic Cancer Cell Invasion.
    Pancreas, 2016, Volume: 45, Issue:7

    Topics: Animals; Blotting, Western; Cattle; Cell Line; Cell Line, Tumor; Cell Movement; Crk-Associated Substrate Protein; Endothelial Cells; Enzyme Inhibitors; Focal Adhesion Protein-Tyrosine Kinases; Humans; Neoplasm Invasiveness; Pancreatic Neoplasms; Phosphorylation; Pulmonary Artery; Rifabutin; Tyrosine

2016
Pancreatic Neuroendocrine Tumors and EMT Behavior Are Driven by the CSC Marker DCLK1.
    Molecular cancer research : MCR, 2017, Volume: 15, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Animals; Biomarkers, Tumor; Cell Line, Tumor; Doublecortin-Like Kinases; Epithelial-Mesenchymal Transition; Female; Focal Adhesion Kinase 1; Humans; Intracellular Signaling Peptides and Proteins; Male; Mice, Inbred BALB C; Middle Aged; Neoplastic Stem Cells; Neuroendocrine Tumors; Pancreatic Neoplasms; Protein Serine-Threonine Kinases; Tyrosine; Xenograft Model Antitumor Assays

2017
Inhibition of STAT3 Tyr705 phosphorylation by Smad4 suppresses transforming growth factor beta-mediated invasion and metastasis in pancreatic cancer cells.
    Cancer research, 2008, Jun-01, Volume: 68, Issue:11

    Topics: Blotting, Western; Cell Line, Tumor; Extracellular Signal-Regulated MAP Kinases; Humans; Neoplasm Invasiveness; Neoplasm Metastasis; Pancreatic Neoplasms; Phosphorylation; Smad4 Protein; STAT3 Transcription Factor; Transforming Growth Factor beta; Tyrosine

2008
In vivo characterization of proliferation for discriminating cancer from pancreatic pseudotumors.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2008, Volume: 49, Issue:9

    Topics: Adult; Aged; Diagnosis, Differential; Female; Granuloma, Plasma Cell; Humans; Image Interpretation, Computer-Assisted; Male; Middle Aged; Neoplasm Invasiveness; Pancreatic Neoplasms; Radionuclide Imaging; Radiopharmaceuticals; Reproducibility of Results; Sensitivity and Specificity; Tyrosine

2008
Glucose-modulated tyrosine nitration in beta cells: targets and consequences.
    Archives of biochemistry and biophysics, 2009, Apr-15, Volume: 484, Issue:2

    Topics: Animals; Chaperonin 60; Diabetes Mellitus; Glucose; Humans; Hyperglycemia; Insulin; Insulin Secretion; Insulin-Secreting Cells; Insulinoma; Islets of Langerhans; Nitrates; Pancreatic Neoplasms; Prediabetic State; Tyrosine

2009
Tyrosine residues at the carboxyl terminus of Vav1 play an important role in regulation of its biological activity.
    The Journal of biological chemistry, 2010, Jul-23, Volume: 285, Issue:30

    Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Cattle; Cell Transformation, Neoplastic; Enzyme Activation; Humans; Jurkat Cells; Mice; Molecular Sequence Data; Mutation; NFATC Transcription Factors; Pancreatic Neoplasms; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-vav; Rats; T-Lymphocytes; Tyrosine

2010
CUB domain-containing protein 1, a prognostic factor for human pancreatic cancers, promotes cell migration and extracellular matrix degradation.
    Cancer research, 2010, Jun-15, Volume: 70, Issue:12

    Topics: Antigens, CD; Antigens, Neoplasm; Blotting, Western; Cell Adhesion; Cell Adhesion Molecules; Cell Movement; Cell Proliferation; Cortactin; Extracellular Matrix; Humans; Immunoenzyme Techniques; Immunoprecipitation; Lymphatic Metastasis; Matrix Metalloproteinase 9; Neoplasm Invasiveness; Neoplasm Proteins; Pancreatic Neoplasms; Phosphorylation; Prognosis; Protein Kinase C-delta; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; Survival Rate; Tumor Cells, Cultured; Tyrosine

2010
MUC1 enhances invasiveness of pancreatic cancer cells by inducing epithelial to mesenchymal transition.
    Oncogene, 2011, Mar-24, Volume: 30, Issue:12

    Topics: Amino Acid Sequence; Animals; Cadherins; Cell Line, Tumor; Epithelial-Mesenchymal Transition; Humans; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Mucin-1; Neoplasm Invasiveness; Neoplasm Metastasis; Pancreatic Neoplasms; Snail Family Transcription Factors; Transcription Factors; Tyrosine

2011
Tyrosine 23 phosphorylation-dependent cell-surface localization of annexin A2 is required for invasion and metastases of pancreatic cancer.
    PloS one, 2011, Apr-29, Volume: 6, Issue:4

    Topics: Animals; Annexin A2; Antibodies, Monoclonal; Antigens, Neoplasm; Biomarkers, Tumor; Blotting, Western; Cancer Vaccines; Cell Line, Tumor; Cell Membrane; Cell Movement; Disease-Free Survival; Epithelial-Mesenchymal Transition; Female; Humans; Liver; Mice; Mice, Inbred C57BL; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasms, Experimental; Pancreatic Neoplasms; Phosphorylation; RNA Interference; Tumor Cells, Cultured; Tyrosine

2011
Nitrocapsanthin and nitrofucoxanthin, respective products of capsanthin and fucoxanthin reaction with peroxynitrite.
    Journal of agricultural and food chemistry, 2011, Oct-12, Volume: 59, Issue:19

    Topics: Animals; Anticarcinogenic Agents; Burkitt Lymphoma; Cell Line, Tumor; Female; Free Radical Scavengers; Humans; Mice; Mice, Inbred ICR; Pancreatic Neoplasms; Papilloma; Peroxynitrous Acid; Skin Neoplasms; Tyrosine; Xanthophylls

2011
Gastrointestinal hormones stimulate growth of Foregut Neuroendocrine Tumors by transactivating the EGF receptor.
    Biochimica et biophysica acta, 2013, Volume: 1833, Issue:3

    Topics: Adenoma, Islet Cell; Animals; Blotting, Western; Cell Proliferation; Epidermal Growth Factor; ErbB Receptors; Gastrointestinal Hormones; Humans; Neuroendocrine Tumors; Pancreatic Neoplasms; Phosphorylation; Rats; Reactive Oxygen Species; Signal Transduction; Somatostatinoma; Transcriptional Activation; Transforming Growth Factor alpha; Tumor Cells, Cultured; Tyrosine

2013
Autocrine-mediated ErbB-2 kinase activation of STAT3 is required for growth factor independence of pancreatic cancer cell lines.
    Oncogene, 2003, Oct-30, Volume: 22, Issue:49

    Topics: CDC2-CDC28 Kinases; Cell Cycle Proteins; Cell Line, Tumor; Cyclin D1; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase Inhibitor p27; DNA-Binding Proteins; ErbB Receptors; Growth Substances; Humans; Pancreatic Neoplasms; Phosphorylation; Receptor, ErbB-2; Retinoblastoma Protein; STAT3 Transcription Factor; Trans-Activators; Tumor Suppressor Proteins; Tyrosine

2003
Inhibition of SRC tyrosine kinase impairs inherent and acquired gemcitabine resistance in human pancreatic adenocarcinoma cells.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Apr-01, Volume: 10, Issue:7

    Topics: Adenocarcinoma; Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Apoptosis; Blotting, Northern; Blotting, Western; Caspases; Cell Cycle Proteins; Cell Division; Cell Line, Tumor; Cell Nucleus; Deoxycytidine; DNA-Binding Proteins; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; E2F Transcription Factors; E2F1 Transcription Factor; Gemcitabine; Genes, Dominant; Humans; Inhibitory Concentration 50; Mice; Mice, Nude; Neoplasm Metastasis; Neoplasm Transplantation; Pancreatic Neoplasms; Phosphorylation; Pyrimidines; Ribonucleoside Diphosphate Reductase; src-Family Kinases; Transcription Factors; Tyrosine

2004
Hypoxia increases resistance of human pancreatic cancer cells to apoptosis induced by gemcitabine.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Apr-01, Volume: 10, Issue:7

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Apoptosis; Blotting, Western; Butadienes; Cell Division; Cell Line, Tumor; Chromones; Deoxycytidine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Gemcitabine; Humans; Hypoxia; Mitogen-Activated Protein Kinases; Morpholines; Neovascularization, Pathologic; NF-kappa B; Nitriles; Oxygen; Pancreatic Neoplasms; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein-Tyrosine Kinases; Pyrimidines; Pyrroles; Signal Transduction; Sp1 Transcription Factor; Time Factors; Tyrosine

2004
Distinctive roles for prolactin and growth hormone in the activation of signal transducer and activator of transcription 5 in pancreatic islets of langerhans.
    Endocrinology, 2004, Volume: 145, Issue:9

    Topics: Animals; Cell Division; Cell Line, Tumor; DNA-Binding Proteins; Growth Hormone; Insulinoma; Islets of Langerhans; Janus Kinase 2; Kinetics; Milk Proteins; Pancreatic Neoplasms; Phosphorylation; Prolactin; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Rats; Signal Transduction; STAT5 Transcription Factor; Trans-Activators; Tyrosine

2004
The dietary isothiocyanate sulforaphane targets pathways of apoptosis, cell cycle arrest, and oxidative stress in human pancreatic cancer cells and inhibits tumor growth in severe combined immunodeficient mice.
    Molecular cancer therapeutics, 2004, Volume: 3, Issue:10

    Topics: Animals; Anticarcinogenic Agents; Antigens; Apoptosis; Blotting, Western; Caspase 3; Caspase 8; Caspases; Cell Cycle; Cell Line, Tumor; Cell Membrane; Cell Nucleus; DNA; Dose-Response Relationship, Drug; Enzyme Activation; Flow Cytometry; Glutathione; Humans; Isothiocyanates; Male; Membrane Potentials; Mice; Mice, SCID; Microscopy, Fluorescence; Mitochondria; Mitosis; Neoplasm Transplantation; Neoplasms; Oxidative Stress; Pancreatic Neoplasms; Reactive Oxygen Species; Staurosporine; Sulfoxides; Thiocyanates; Time Factors; Tyrosine

2004
Farnesyl transferase inhibitor (R115777)-induced inhibition of STAT3(Tyr705) phosphorylation in human pancreatic cancer cell lines require extracellular signal-regulated kinases.
    Cancer research, 2005, Apr-01, Volume: 65, Issue:7

    Topics: Adenocarcinoma; Alkyl and Aryl Transferases; Cell Cycle Proteins; Cell Growth Processes; Cyclin-Dependent Kinase Inhibitor p21; DNA-Binding Proteins; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Farnesyltranstransferase; Humans; Interleukin-6; Pancreatic Neoplasms; Phosphorylation; Proto-Oncogene Proteins c-myc; Quinolones; Serine; STAT3 Transcription Factor; Trans-Activators; Tyrosine; Up-Regulation

2005
An ITIM-like motif within the CCK2 receptor sequence required for interaction with SHP-2 and the activation of the AKT pathway.
    Biochimica et biophysica acta, 2006, Volume: 1763, Issue:10

    Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Cell Line, Tumor; Chlorocebus aethiops; COS Cells; Gastrins; Intracellular Signaling Peptides and Proteins; Mice; Molecular Sequence Data; NIH 3T3 Cells; Pancreatic Neoplasms; Phosphorylation; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins c-akt; Rats; Receptor, Cholecystokinin B; Signal Transduction; Tyrosine

2006
Platelet-derived growth factor receptor beta-mediated phosphorylation of MUC1 enhances invasiveness in pancreatic adenocarcinoma cells.
    Cancer research, 2007, Jun-01, Volume: 67, Issue:11

    Topics: Adenocarcinoma; Amino Acid Motifs; Amino Acid Sequence; Animals; Antigens, Neoplasm; beta Catenin; Binding Sites; Cell Line, Tumor; Cell Nucleus; Female; Humans; Mass Spectrometry; Mice; Mice, Nude; Molecular Sequence Data; Mucin-1; Mucins; Neoplasm Invasiveness; Pancreatic Neoplasms; Phosphorylation; Receptor, Platelet-Derived Growth Factor beta; Tyrosine

2007
Characterization of the CXCR4 signaling in pancreatic cancer cells.
    International journal of gastrointestinal cancer, 2006, Volume: 37, Issue:4

    Topics: Aorta; Blotting, Western; Cell Adhesion; Cell Movement; Cell Proliferation; Endothelium, Vascular; Enzyme Inhibitors; ErbB Receptors; Gene Expression Profiling; Humans; Hyaluronan Receptors; Hypoxia-Inducible Factor 1, alpha Subunit; Immunoprecipitation; Interleukin-8; MAP Kinase Signaling System; Neovascularization, Physiologic; Oligonucleotide Array Sequence Analysis; Pancreatic Neoplasms; Phosphatidylinositol 3-Kinases; Phosphorylation; Receptors, CXCR4; Signal Transduction; Tyrosine; Vascular Endothelial Growth Factor A

2006
Receptor tyrosine kinase signaling required for integrin alpha v beta 5-directed cell motility but not adhesion on vitronectin.
    The Journal of cell biology, 1994, Volume: 127, Issue:3

    Topics: Cell Adhesion; Cell Line; Cell Movement; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; Flow Cytometry; Genistein; Glycoproteins; Humans; Insulin-Like Growth Factor I; Integrins; Isoflavones; Kinetics; Naphthalenes; Nitriles; Pancreatic Neoplasms; Phosphotyrosine; Polycyclic Compounds; Protein Kinase C; Receptor Protein-Tyrosine Kinases; Receptor, IGF Type 1; Receptors, Vitronectin; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tyrosine; Tyrphostins; Vitronectin

1994
Inhibition of pancreatic cancer cell growth in vitro by the tyrphostin group of tyrosine kinase inhibitors.
    British journal of cancer, 1993, Volume: 68, Issue:6

    Topics: Catechols; Cell Division; DNA, Neoplasm; Dose-Response Relationship, Drug; Epidermal Growth Factor; Humans; Immunoblotting; Nitriles; Pancreatic Ducts; Pancreatic Neoplasms; Phenols; Phosphorylation; Platelet-Derived Growth Factor; Protein-Tyrosine Kinases; Tumor Cells, Cultured; Tyrosine; Tyrphostins

1993
Inhibition of in vitro tumor cell invasion by ginsenoside Rg3.
    Japanese journal of cancer research : Gann, 1996, Volume: 87, Issue:4

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Carbohydrate Sequence; Carcinoma, Small Cell; Ginsenosides; Humans; Liver Neoplasms, Experimental; Lung Neoplasms; Lysophospholipids; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Proteins; Pancreatic Neoplasms; Phosphorylation; Rats; Rats, Inbred Strains; Saponins; Tyrosine

1996
Expression of a truncated EGF receptor is associated with inhibition of pancreatic cancer cell growth and enhanced sensitivity to cisplatinum.
    International journal of cancer, 1996, Dec-11, Volume: 68, Issue:6

    Topics: Antineoplastic Agents; Cell Division; Cisplatin; ErbB Receptors; Humans; Pancreatic Neoplasms; Proto-Oncogene Proteins c-fos; RNA, Antisense; Signal Transduction; Tumor Cells, Cultured; Tyrosine

1996
CAS/Crk coupling serves as a "molecular switch" for induction of cell migration.
    The Journal of cell biology, 1998, Feb-23, Volume: 140, Issue:4

    Topics: Animals; Cell Membrane; Cell Movement; COS Cells; Crk-Associated Substrate Protein; Extracellular Matrix; Gene Expression; GTP-Binding Proteins; Humans; Hypoglycemic Agents; Insulin; Membrane Proteins; Neoplasm Metastasis; Pancreas; Pancreatic Neoplasms; Phosphoproteins; Phosphorylation; Protein Binding; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-crk; Rabbits; rac GTP-Binding Proteins; ras Proteins; Retinoblastoma-Like Protein p130; src Homology Domains; Tumor Cells, Cultured; Tyrosine

1998
Role of tyrosine phosphorylation in leptin activation of ATP-sensitive K+ channels in the rat insulinoma cell line CRI-G1.
    The Journal of physiology, 1998, Jul-01, Volume: 510 ( Pt 1)

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphate; Adenylyl Imidodiphosphate; Androstadienes; Animals; Enzyme Inhibitors; Insulinoma; Leptin; Nitriles; Pancreatic Neoplasms; Phosphoric Monoester Hydrolases; Phosphorylation; Potassium Channels; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Proteins; Rats; Tumor Cells, Cultured; Tyrosine; Tyrphostins; Wortmannin

1998
Src stimulates insulin-like growth factor I (IGF-I)-dependent cell proliferation by increasing IGF-I receptor number in human pancreatic carcinoma cells.
    Cancer research, 1998, Aug-15, Volume: 58, Issue:16

    Topics: Cell Division; Humans; Insulin-Like Growth Factor I; Neoplasm Proteins; Pancreatic Neoplasms; Phosphorylation; Proto-Oncogene Proteins pp60(c-src); Receptor, IGF Type 1; Tumor Cells, Cultured; Tyrosine

1998
Association of increased immunostaining for inducible nitric oxide synthase and nitrotyrosine with fibroblast growth factor transformation in pancreatic cancer.
    Archives of surgery (Chicago, Ill. : 1960), 1999, Volume: 134, Issue:3

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Fibroblast Growth Factors; Humans; Immunohistochemistry; Nitric Oxide Synthase; Pancreatic Neoplasms; Retrospective Studies; Tyrosine

1999
Protein metabolism in glucagonoma.
    Diabetologia, 1999, Volume: 42, Issue:3

    Topics: Adult; Amino Acids; Blood Glucose; C-Peptide; Deuterium; Female; Glucagon; Glucagonoma; Humans; Infusions, Intravenous; Insulin; Leucine; Male; Middle Aged; Pancreatic Neoplasms; Phenylalanine; Protein Biosynthesis; Proteins; Reference Values; Tyrosine

1999
Tyrosine nitration of c-SRC tyrosine kinase in human pancreatic ductal adenocarcinoma.
    Archives of biochemistry and biophysics, 2000, May-15, Volume: 377, Issue:2

    Topics: Adenocarcinoma; Blotting, Western; Chromatography, High Pressure Liquid; Cortactin; Humans; Microfilament Proteins; Nitrates; Pancreatic Neoplasms; Phosphorylation; Phosphotyrosine; Precipitin Tests; Protein Conformation; Protein Folding; Proto-Oncogene Proteins pp60(c-src); Tumor Cells, Cultured; Tyrosine

2000
Inhibition of growth and metastatic progression of pancreatic carcinoma in hamster after somatostatin receptor subtype 2 (sst2) gene expression and administration of cytotoxic somatostatin analog AN-238.
    Proceedings of the National Academy of Sciences of the United States of America, 2000, Aug-01, Volume: 97, Issue:16

    Topics: Animals; Antibiotics, Antineoplastic; Cadherins; Cell Division; Cricetinae; Cytotoxins; Doxorubicin; Fungal Proteins; GTPase-Activating Proteins; Intracellular Signaling Peptides and Proteins; Male; Mesocricetus; Neoplasm Metastasis; Pancreatic Neoplasms; Phosphorylation; Protein Phosphatase 1; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Pyrroles; Saccharomyces cerevisiae Proteins; Tumor Cells, Cultured; Tyrosine

2000
12-lipoxygenase metabolite 12(S)-HETE stimulates human pancreatic cancer cell proliferation via protein tyrosine phosphorylation and ERK activation.
    International journal of cancer, 2001, Dec-01, Volume: 94, Issue:5

    Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Cell Division; DNA; Enzyme Activation; Genistein; Humans; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinases; Pancreatic Neoplasms; Phosphorylation; Tumor Cells, Cultured; Tyrosine

2001
FGF-1 and FGF-2 regulate the expression of E-cadherin and catenins in pancreatic adenocarcinoma.
    International journal of cancer, 2001, Dec-01, Volume: 94, Issue:5

    Topics: Adenocarcinoma; alpha Catenin; beta Catenin; Cadherins; Cell Communication; Cytoskeletal Proteins; Fibroblast Growth Factor 1; Fibroblast Growth Factor 2; Humans; Pancreatic Neoplasms; Phosphorylation; Trans-Activators; Tumor Cells, Cultured; Tyrosine

2001
Letter: Diagnosis of exocrine pancreatic disease by synthetic peptide.
    Lancet (London, England), 1976, Jul-10, Volume: 2, Issue:7976

    Topics: Adult; Aminobenzoates; Humans; Pancreatic Neoplasms; Pancreatitis; Trypsin; Tyrosine

1976
Diagnosis of pancreatic disease by a synthetic peptide. A new test of exocrine pancreatic function.
    Lancet (London, England), 1976, Mar-27, Volume: 1, Issue:7961

    Topics: 4-Aminobenzoic Acid; Adenocarcinoma; Adult; Aminobenzoates; Chronic Disease; Dipeptides; Female; Humans; Male; Middle Aged; Pancreas; Pancreatic Neoplasms; Pancreatitis; para-Aminobenzoates; Tyrosine

1976
Effects of epidermal growth factor and analogues of luteinizing hormone-releasing hormone and somatostatin on phosphorylation and dephosphorylation of tyrosine residues of specific protein substrates in various tumors.
    Proceedings of the National Academy of Sciences of the United States of America, 1991, Mar-01, Volume: 88, Issue:5

    Topics: Amino Acid Sequence; Animals; Antineoplastic Agents; Autoradiography; Breast Neoplasms; Cell Line; Colonic Neoplasms; Epidermal Growth Factor; Gonadotropin-Releasing Hormone; Humans; Kinetics; Lung Neoplasms; Membrane Proteins; Molecular Sequence Data; Pancreatic Neoplasms; Phosphorus Radioisotopes; Phosphorylation; Protein Kinases; Protein-Tyrosine Kinases; Somatostatin; Triptorelin Pamoate; Tyrosine

1991
Differential binding and biological activities of epidermal growth factor and transforming growth factor alpha in a human pancreatic cancer cell line.
    Cancer research, 1991, Dec-01, Volume: 51, Issue:23 Pt 1

    Topics: Epidermal Growth Factor; ErbB Receptors; Humans; Hydrogen-Ion Concentration; Inositol 1,4,5-Trisphosphate; Iodine Radioisotopes; Pancreatic Neoplasms; Phosphorylation; Statistics as Topic; Transforming Growth Factor alpha; Tumor Cells, Cultured; Tyrosine

1991
Somatostatin receptor imaging with 123I-Tyr3-Octreotide.
    Zeitschrift fur Gastroenterologie, 1990, Volume: 28 Suppl 2

    Topics: Autoradiography; Brain Neoplasms; Breast Neoplasms; Humans; Iodine Radioisotopes; Multiple Endocrine Neoplasia; Octreotide; Pancreatic Neoplasms; Radiography; Radionuclide Imaging; Receptors, Neurotransmitter; Receptors, Somatostatin; Somatostatin; Tyrosine

1990
Reduced tyrosine phosphorylation and nonresponsiveness to EGF-mediated cytotoxicity in EGF receptor-hyperproducing UCVA-1 cells.
    Cellular signalling, 1990, Volume: 2, Issue:3

    Topics: Carcinoma, Squamous Cell; Cell Division; Down-Regulation; Epidermal Growth Factor; ErbB Receptors; Humans; Pancreatic Neoplasms; Peptide Mapping; Phosphatidylinositols; Phosphoproteins; Phosphorylation; Protein-Tyrosine Kinases; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tyrosine

1990
The genesis of apudamyloid in endocrine polypeptide tumours: histochemical distinction from immunamyloid.
    Virchows Archiv. B, Cell pathology, 1972, Volume: 10, Issue:2

    Topics: Adenocarcinoma, Scirrhous; Adenoma, Islet Cell; Adrenal Gland Neoplasms; Amyloidosis; Arthritis, Rheumatoid; Carcinoma; Endocrine System Diseases; Histocytochemistry; Humans; Microscopy, Electron; Neoplasm Proteins; Neoplasms; Pancreatic Neoplasms; Pheochromocytoma; Thyroid Neoplasms; Tryptophan Oxygenase; Tyrosine

1972
Fibrinaemia and multiple thrombi in pancreatic carcinoma. A case studied with quantitative N-terminal analysis.
    Scandinavian journal of haematology, 1972, Volume: 9, Issue:4

    Topics: Alanine; Blood Coagulation; Blood Coagulation Tests; Disseminated Intravascular Coagulation; Fibrin; Fibrinogen; Glycine; Heparin; Humans; Male; Methods; Middle Aged; Pancreatic Neoplasms; Thrombin; Thrombophlebitis; Tyrosine; Warfarin

1972
[The effect of thyroid hormone on tumor cells in a tissue culture].
    Voprosy onkologii, 1968, Volume: 14, Issue:4

    Topics: Animals; Culture Techniques; Diiodotyrosine; Embryo, Mammalian; Female; Humans; Mitosis; Ovarian Neoplasms; Pancreatic Neoplasms; Pregnancy; Rabbits; Thyroid Hormones; Tyrosine

1968