tyrosine has been researched along with Ovarian Neoplasms in 53 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (5.66) | 18.7374 |
| 1990's | 10 (18.87) | 18.2507 |
| 2000's | 25 (47.17) | 29.6817 |
| 2010's | 10 (18.87) | 24.3611 |
| 2020's | 5 (9.43) | 2.80 |
| Authors | Studies |
|---|---|
| Cao, J; Chen, J; Chen, L; Chen, S; Fan, G; Hao, P; Hou, L; Li, D; Wang, Y; Xiong, X; Zhang, J; Zhang, Y; Zhao, X; Zhu, Q; Zhuang, M | 1 |
| Gong, JL; Gu, B; Lan, T; Li, SB; Li, Y; Luo, L; Ma, P; Mu, CY; Tao, AB; Wang, Y; Wang, ZC; Xu, H; Zhou, Y | 1 |
| Çalışkan, E; Çapan, İ; Erkan, S; Görgülü, AO; Kaplan, A; Koran, K; Sandal, S; Şekerci, G; Tekin, S | 1 |
| Chen, Y; Chen, Z; Deng, C; Guo, H; Huang, H; Huang, X; Jiang, Y; Li, B; Li, J; Liu, J; Lu, J; Mai, Q; Pan, C; Pan, W; Wu, Z; Yao, S; Zhang, C; Zhang, S; Zheng, C | 1 |
| Fujiwara, H; Koyanagi, T; Mizukami, H; Saga, Y; Takahashi, S; Takahashi, Y; Takei, Y; Tamura, K; Taneichi, A; Urabe, M; Yoshiba, T | 1 |
| Chan, DW; Chen, L; Moore, C; Shih, IM; Song, G; Song, Q; Wang, TL; Yu, Y; Zhang, B; Zhang, H; Zhang, Z; Zhu, H | 1 |
| Haidari, M; Wakame, K; Zhang, W | 1 |
| Akbani, R; Armaiz-Pena, GN; Baggerly, KA; Bottsford-Miller, J; Coleman, RL; Dalton, HJ; DeGeest, K; Diao, L; Kang, Y; Lopez-Berestein, G; Lutgendorf, S; Nick, AM; Sanguino, AM; Sood, AK; Stone, RL; Thanapprapasr, D; Zand, B | 1 |
| Albitar, L; Aponte, M; Cramer, DW; Edwards, D; Jiang, W; Lakkis, M; Li, MJ; Mok, SC; Vitonis, A; Ye, B | 1 |
| Fuchs, D; Grahmann, AV; Klieber, M; Ledochowski, M; Neurauter, G; Sperner-Unterweger, B; Zeimet, A | 1 |
| Barsukov, AN; Pavlova, NF | 1 |
| Bagnato, A; Biroccio, A; Cianfrocca, R; Di Castro, V; Masi, S; Natali, PG; Nicotra, MR; Rosanò, L; Salvati, E; Spinella, F | 1 |
| Bloigu, R; Karihtala, P; Puistola, U; Soini, Y; Vaskivuo, L | 1 |
| Bianchi, M; Boulay, A; Duss, S; Heinrich, C; Hofsteenge, J; Hynes, NE; Keller, C; Lienhard, S; Sack, R; Vecchi, M | 1 |
| Freedman, RS; Helm, CW; Jung, WJ; Oleszak, EL; Pappas, J; Platsoucas, CD; Tsygankov, AY; Wolfson, AD | 1 |
| Karihtala, P; Kauppila, S; Puistola, U; Pylväs, M; Soini, Y | 1 |
| Bachvarov, D; Bachvarova, M; Bascands, JL; Gera, L; Jutras, S; Keita, M; Mes-Masson, AM; Stewart, JM | 1 |
| Ahmed, AA; Bast, RC; Claret, FX; He, G; Hung, MC; Le, XF; Mao, W; Siddik, ZH; Xia, W | 1 |
| Asselin, E; Bérubé, G; Brasseur, K; Descôteaux, C; Leblanc, V; Parent, S | 1 |
| Chen, C; Huang, YW; Li, JD; Xiao, J; Xu, MM; Zhu, XF | 1 |
| Allen, JK; Armaiz-Pena, GN; Bar-Eli, M; Cole, SW; Cruz, A; De Geest, K; Deavers, MT; English, RD; Gallick, GE; Gharpure, KM; Han, LY; Jackson, DB; Lin, YG; Lopez, GE; Lopez-Berestein, G; Lutgendorf, SK; Mangala, LS; Nagaraja, AS; Nick, AM; Rodriguez-Aguayo, C; Shahzad, MM; Shazhad, MM; Soldatos, TG; Soman, KV; Sood, AK; Stone, RL; Torres-Lugo, M; Villares, GJ; Vivas-Mejia, P; Wiktorowicz, JE; Wu, Z; Young, T; Zien, A; Zigler, M | 1 |
| Conus, NM; Cristiano, BE; Hannan, KM; Hemmings, BA; Pearson, RB | 1 |
| Ikebuchi, Y; Kawagishi, R; Morishige, K; Murata, Y; Sawada, K; Tahara, M; Tasaka, K | 1 |
| Ikebuchi, Y; Kawagishi, R; Morishige, Ki; Murata, Y; Sawada, K; Tahara, M; Tasaka, K | 1 |
| Jaspars, M; Tabudravu, JN | 1 |
| Bagnato, A; Di Castro, V; Natali, PG; Nicotra, MR; Rosanò, L; Spinella, F | 1 |
| Mizukami, H; Ozawa, K; Saga, Y; Suzuki, M; Takei, Y | 1 |
| Cho, H; Hong, J; Im, KS; Jung, JH; Kim, DK; Lee, CO; Liu, Y; Park, Y | 1 |
| Barber, DL; Lin, J; Reid, TJ; Sondak, VK; Song, H | 1 |
| Chen, HZ; Ding, ZM; Lu, WG; Xie, X; Ye, DF; Ye, F | 1 |
| Annable, T; Fojo, T; Greenberger, LM; Kim, JH; Loganzo, F; Nogales, E; Poruchynsky, MS; Sackett, DL | 1 |
| Agarwal, C; Agarwal, R; Sclafani, RA; Singh, RP; Siriwardana, S; Tyagi, A | 1 |
| Clark, DE; Jones, FE; Marrero, L; Vidal, GA | 1 |
| Cai, G; Ke, Z; Luo, J; Wang, J; Xin, X | 1 |
| Bacus, SS; Chace, D; Chin, DM; Cohen, BD; Goetze, A; Green, JM; Hellström, I; Mixan, B; Plowman, GD; Siegall, CB | 1 |
| Casey, G; Fang, XJ; Mills, GB; Xu, Y | 1 |
| Arad-Dann, H; Beller, U; Ben-Sasson, SA; Gavrieli, Y; Haimovitch, R | 1 |
| Hamburger, AW; Mishra, S | 1 |
| Cummings, J; Macpherson, JS; Meikle, I; Smyth, JF | 1 |
| Buczek-Thomas, JA; Chen, N; Hasan, T | 1 |
| Bell, MC; Crowley-Nowick, PA; Lai, P; Mantovani, G; Rabinowich, H; Whiteside, TL | 1 |
| Ali, S; Campiglio, M; Knyazev, PG; Ullrich, A | 1 |
| McGuckin, MA; Quin, RJ | 1 |
| Bagnato, A; Catt, KJ; Tecce, R; Vacca, F | 1 |
| Bourguignon, LY; Chen, YW; Shao, L; Zhu, H | 1 |
| Chambers, JT; Chambers, SK; Flick, MB; Kacinski, BM; Toy, EP | 1 |
| Chen, X; Chenevix-Trench, G; Green, A; Purdie, DM; Spurdle, AB; Webb, PM | 1 |
| Chen, Z; Fadiel, A; Feng, Y; Naftolin, F; Ohtani, K; Rutherford, T | 1 |
| Jallal, B; Schlessinger, J; Ullrich, A | 1 |
| Fridman, R; Hamilton, TC; Kanemoto, T; Martin, GR | 1 |
| Bremer, EG; Hakomori, S; Schlessinger, J | 1 |
| Brandt, MB; Kuttner, RE; Lorincz, AB | 1 |
| Arkhipenko, VI; Spitsa, AI | 1 |
53 other study(ies) available for tyrosine and Ovarian Neoplasms
| Article | Year |
|---|---|
FER-mediated phosphorylation and PIK3R2 recruitment on IRS4 promotes AKT activation and tumorigenesis in ovarian cancer cells.
Topics: Carcinogenesis; Carcinoma, Ovarian Epithelial; Cell Transformation, Neoplastic; Enzyme Activation; Female; Humans; Insulin Receptor Substrate Proteins; Ovarian Neoplasms; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-akt; Tyrosine | 2022 |
Increased endogenous PKG I activity attenuates EGF-induced proliferation and migration of epithelial ovarian cancer via the MAPK/ERK pathway.
Topics: Animals; Carcinoma, Ovarian Epithelial; Cell Line, Tumor; Cell Proliferation; Epidermal Growth Factor; ErbB Receptors; Female; Humans; MAP Kinase Signaling System; Mice; Ovarian Neoplasms; Phosphorylation; Tyrosine | 2023 |
Synthesis, docking studies, in vitro cytotoxicity evaluation and DNA damage mechanism of new tyrosine-based tripeptides.
Topics: Antineoplastic Agents; Caco-2 Cells; Cell Line, Tumor; Cell Proliferation; DNA Damage; Drug Screening Assays, Antitumor; Female; Humans; Male; Molecular Docking Simulation; Molecular Structure; Ovarian Neoplasms; Structure-Activity Relationship; Tyrosine | 2023 |
Tyrosine catabolism enhances genotoxic chemotherapy by suppressing translesion DNA synthesis in epithelial ovarian cancer.
Topics: Carcinoma, Ovarian Epithelial; DNA; DNA Damage; Female; Fumarates; Humans; Ovarian Neoplasms; Tyrosine | 2023 |
Knockout of vasohibin-2 reduces tubulin carboxypeptidase activity and increases paclitaxel sensitivity in ovarian cancer.
Topics: Angiogenic Proteins; Antineoplastic Agents, Phytogenic; Carboxypeptidases; Cell Culture Techniques; Cell Line, Tumor; Cell Proliferation; CRISPR-Cas Systems; Cyclin B1; Female; Gene Knockdown Techniques; Humans; Ovarian Neoplasms; Paclitaxel; Tubulin; Tyrosine | 2021 |
Proteome-wide Tyrosine Phosphorylation Analysis Reveals Dysregulated Signaling Pathways in Ovarian Tumors.
Topics: Acetylation; Cell Line, Tumor; Cystadenocarcinoma, Serous; Female; Focal Adhesion Kinase 1; Focal Adhesion Kinase 2; Humans; Lysine; Ovarian Neoplasms; Phosphorylation; Protein Processing, Post-Translational; Protein-Tyrosine Kinases; Proteomics; Sumoylation; Tyrosine; Ubiquitination | 2019 |
Disruption of endothelial adherens junction by invasive breast cancer cells is mediated by reactive oxygen species and is attenuated by AHCC.
Topics: Acetylcysteine; Adherens Junctions; Antigens, CD; Antineoplastic Agents, Phytogenic; Antioxidants; beta Catenin; Breast Neoplasms; Cadherins; Cell Movement; Endothelial Cells; Endothelium, Vascular; Female; Human Umbilical Vein Endothelial Cells; Humans; Hydrogen Peroxide; Male; Ovarian Neoplasms; Plant Extracts; Prostatic Neoplasms; Reactive Oxygen Species; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tyrosine | 2013 |
Focal adhesion kinase: an alternative focus for anti-angiogenesis therapy in ovarian cancer.
Topics: Angiogenesis Inhibitors; Animals; Carcinoma, Ovarian Epithelial; Cell Movement; Cell Proliferation; Endothelial Cells; Female; Focal Adhesion Protein-Tyrosine Kinases; Gene Dosage; Humans; Indoles; Mice, Nude; Neoplasm Metastasis; Neoplasms, Glandular and Epithelial; Neovascularization, Pathologic; Ovarian Neoplasms; Phosphorylation; Protein Kinase Inhibitors; Sulfonamides; Tyrosine | 2014 |
Activation of platelet-activating factor receptor and pleiotropic effects on tyrosine phospho-EGFR/Src/FAK/paxillin in ovarian cancer.
Topics: Cell Line, Tumor; Disease Progression; ErbB Receptors; Female; Focal Adhesion Protein-Tyrosine Kinases; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Models, Biological; Neoplasm Invasiveness; Ovarian Neoplasms; Paxillin; Platelet Membrane Glycoproteins; Receptors, G-Protein-Coupled; Signal Transduction; src-Family Kinases; Tyrosine | 2008 |
Serum phenylalanine concentrations in patients with ovarian carcinoma correlate with concentrations of immune activation markers and of isoprostane-8.
Topics: Biomarkers; Biomarkers, Tumor; Cystadenocarcinoma; Endometrial Neoplasms; Female; HIV Infections; Humans; Isoprostanes; Lymphocyte Activation; Neoplasm Staging; Neopterin; Ovarian Neoplasms; Oxidative Stress; Phenylalanine; Receptors, Tumor Necrosis Factor, Type II; Sepsis; Tyrosine; Uterine Neoplasms | 2008 |
[Tyrosine-containing peptides in the estimation of endogenous intoxication in ovarian cancer].
Topics: Adult; Aged; Biomarkers; Diagnosis, Differential; Female; Humans; Middle Aged; Ovarian Cysts; Ovarian Neoplasms; Peptides; Sensitivity and Specificity; Severity of Illness Index; Tyrosine | 2008 |
Beta-arrestin links endothelin A receptor to beta-catenin signaling to induce ovarian cancer cell invasion and metastasis.
Topics: Arrestins; beta Catenin; beta-Arrestin 1; beta-Arrestin 2; beta-Arrestins; Blotting, Western; Cell Line, Tumor; ErbB Receptors; Female; Humans; Microscopy, Fluorescence; Neoplasm Invasiveness; Neoplasm Metastasis; Ovarian Neoplasms; Phosphorylation; Receptor, Endothelin A; Signal Transduction; Transcriptional Activation; Transplantation, Heterologous; Tyrosine | 2009 |
DNA adduct 8-hydroxydeoxyguanosine, a novel putative marker of prognostic significance in ovarian carcinoma.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Antioxidants; Biomarkers, Tumor; Carcinoma; Cell Nucleus; Cytoplasm; DNA Adducts; Female; Guanine; Humans; Immunohistochemistry; Neoplasm Staging; Ovarian Neoplasms; Oxidative Stress; Prognosis; Survival Analysis; Tyrosine | 2009 |
Copine-III interacts with ErbB2 and promotes tumor cell migration.
Topics: Binding Sites; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Male; Models, Biological; Ovarian Neoplasms; Phosphoproteins; Prostatic Neoplasms; Protein Binding; Receptor, ErbB-2; RNA Interference; Tyrosine | 2010 |
Differential expression of CD3zeta message and protein in tumor infiltrating lymphocytes from solid tumor specimens and malignant ascites from patients with ovarian carcinoma.
Topics: Aged; Aged, 80 and over; Ascites; CD3 Complex; Down-Regulation; Female; Humans; Immunoprecipitation; Lymphocytes, Tumor-Infiltrating; Middle Aged; Ovarian Neoplasms; Phosphorylation; Tyrosine | 2009 |
Oxidative stress-induced antioxidant enzyme expression is an early phenomenon in ovarian carcinogenesis.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Adenocarcinoma, Mucinous; Antioxidants; Biomarkers, Tumor; Deoxyguanosine; Female; Humans; Immunohistochemistry; Neoplasm Proteins; Ovarian Neoplasms; Oxidative Stress; Peroxiredoxins; Reactive Oxygen Species; Thioredoxins; Tyrosine | 2010 |
Strong cytotoxic effect of the bradykinin antagonist BKM-570 in ovarian cancer cells--analysis of the molecular mechanisms of its antiproliferative action.
Topics: Antineoplastic Agents; Bradykinin; Cell Line, Tumor; Cell Proliferation; Cisplatin; Drug Screening Assays, Antitumor; Drug Synergism; Female; Gene Expression Profiling; Humans; Oligonucleotide Array Sequence Analysis; Ovarian Neoplasms; Receptors, Bradykinin; Reverse Transcriptase Polymerase Chain Reaction; Tyrosine | 2010 |
The role of p27(Kip1) in dasatinib-enhanced paclitaxel cytotoxicity in human ovarian cancer cells.
Topics: Animals; Antineoplastic Agents; Apoptosis; Caspase 3; CDC2 Protein Kinase; Cell Line, Tumor; Cell Proliferation; Confounding Factors, Epidemiologic; Cyclin-Dependent Kinase Inhibitor p27; Dasatinib; Drug Synergism; Female; Flow Cytometry; Fluorescent Antibody Technique; Gene Expression Regulation, Neoplastic; Genes, bcl-1; Humans; Immunoblotting; Immunoprecipitation; In Situ Nick-End Labeling; Mice; Mice, Nude; Ovarian Neoplasms; Paclitaxel; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-abl; Pyrimidines; Research Design; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; Serine; src-Family Kinases; Thiazoles; Threonine; Tyrosine; Xenograft Model Antitumor Assays | 2011 |
Design of novel tyrosine-nitrogen mustard hybrid molecules active against uterine, ovarian and breast cancer cell lines.
Topics: Antineoplastic Agents, Alkylating; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Chlorambucil; Drug Design; Estrogen Receptor alpha; Female; Humans; Inhibitory Concentration 50; Models, Chemical; Molecular Structure; Ovarian Neoplasms; Tyrosine; Uterine Neoplasms | 2012 |
Expression of c-Src and phospho-Src in epithelial ovarian carcinoma.
Topics: Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Carcinoma, Ovarian Epithelial; Case-Control Studies; CSK Tyrosine-Protein Kinase; Female; Humans; Kaplan-Meier Estimate; Middle Aged; Neoplasms, Glandular and Epithelial; Ovarian Neoplasms; Ovary; Phosphoproteins; Phosphorylation; Predictive Value of Tests; Prognosis; Reference Values; src-Family Kinases; Survival Rate; Tyrosine; Young Adult | 2013 |
Src activation by β-adrenoreceptors is a key switch for tumour metastasis.
Topics: Adrenergic beta-Antagonists; Animals; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Female; Humans; Mice; Models, Molecular; Neoplasm Invasiveness; Neoplasm Metastasis; Norepinephrine; Ovarian Neoplasms; Phosphorylation; Phosphoserine; Receptors, Adrenergic, beta; Signal Transduction; src-Family Kinases; Stress, Physiological; Survival Analysis; Tyrosine | 2013 |
Direct identification of tyrosine 474 as a regulatory phosphorylation site for the Akt protein kinase.
Topics: Animals; Carcinoma; COS Cells; Culture Media, Serum-Free; Enzyme Inhibitors; Female; Genes, Reporter; Humans; Insulin-Like Growth Factor I; Mutagenesis, Site-Directed; Ovarian Neoplasms; Peptide Mapping; Phosphatidylinositol 3-Kinases; Phosphopeptides; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Recombinant Fusion Proteins; Tumor Cells, Cultured; Tyrosine; Vanadates | 2002 |
Alendronate inhibits lysophosphatidic acid-induced migration of human ovarian cancer cells by attenuating the activation of rho.
Topics: Alendronate; Cell Movement; Cell Survival; Cytoskeletal Proteins; Diterpenes; Drug Interactions; Enzyme Activation; Female; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Humans; Lysophospholipids; Myosin Light Chains; Ovarian Neoplasms; Paxillin; Phosphoproteins; Phosphorylation; Protein-Tyrosine Kinases; rho GTP-Binding Proteins; Tumor Cells, Cultured; Tyrosine | 2002 |
Lysophosphatidic acid induces focal adhesion assembly through Rho/Rho-associated kinase pathway in human ovarian cancer cells.
Topics: Cell Movement; Cytoskeletal Proteins; Enzyme Inhibitors; Female; Focal Adhesions; Humans; Intracellular Signaling Peptides and Proteins; Lysophospholipids; Myosin-Light-Chain Kinase; Myosin-Light-Chain Phosphatase; Ovarian Neoplasms; Paxillin; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Protein Serine-Threonine Kinases; rho GTP-Binding Proteins; rho-Associated Kinases; Signal Transduction; Stress Fibers; Tumor Cells, Cultured; Tyrosine | 2002 |
Purealidin S and purpuramine J, bromotyrosine alkaloids from the Fijian marine sponge Druinella sp.
Topics: Alkaloids; Animals; Antineoplastic Agents; Bromobenzenes; Drug Screening Assays, Antitumor; Female; Fiji; Humans; Leukemia; Molecular Structure; Ovarian Neoplasms; Porifera; Tumor Cells, Cultured; Tyrosine | 2002 |
Endothelin-1 decreases gap junctional intercellular communication by inducing phosphorylation of connexin 43 in human ovarian carcinoma cells.
Topics: Animals; Cell Division; Cell Line, Tumor; Connexin 43; Disease Progression; Endothelin-1; Female; Humans; Immunoblotting; Kinetics; Mice; Mice, Nude; Neoplasm Transplantation; Ovarian Neoplasms; Phosphorylation; Precipitin Tests; Time Factors; Tyrosine | 2003 |
Suppression of cell migration in ovarian cancer cells mediated by PTEN overexpression.
Topics: Animals; Blotting, Western; Calcium Phosphates; Cell Line, Tumor; Cell Movement; Cloning, Molecular; Disease Progression; DNA, Complementary; Female; Gene Library; Humans; Kinetics; Liver; Mice; Mice, Inbred BALB C; Ovarian Neoplasms; Phosphoric Monoester Hydrolases; Phosphorylation; Plasmids; Prognosis; PTEN Phosphohydrolase; Time Factors; Transfection; Tumor Suppressor Proteins; Tyrosine; Wound Healing | 2003 |
New bromotyrosine derivatives from an association of two sponges, Jaspis wondoensis and Poecillastra wondoensis.
Topics: Animals; Antineoplastic Agents, Phytogenic; Central Nervous System Neoplasms; Colonic Neoplasms; Disulfides; Drug Screening Assays, Antitumor; Electron Spin Resonance Spectroscopy; Female; Humans; Korea; Lung Neoplasms; Methicillin Resistance; Microbial Sensitivity Tests; Ofloxacin; Ovarian Neoplasms; Porifera; Skin Neoplasms; Staphylococcus; Tumor Cells, Cultured; Tyrosine | 2003 |
Modulation of Janus kinase 2 by cisplatin in cancer cells.
Topics: Antineoplastic Agents; Apoptosis; bcl-X Protein; Carrier Proteins; Cisplatin; DNA-Binding Proteins; Female; Humans; Intracellular Signaling Peptides and Proteins; Janus Kinase 2; Oncogene Proteins, Fusion; Ovarian Neoplasms; Phosphorylation; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Repressor Proteins; Sarcoma; Signal Transduction; STAT3 Transcription Factor; Suppressor of Cytokine Signaling 1 Protein; Suppressor of Cytokine Signaling Proteins; Trans-Activators; Tumor Cells, Cultured; Tyrosine | 2004 |
Vascular endothelial growth factor (VEGF) and ovarian carcinoma cell supernatant activate signal transducers and activators of transcription (STATs) via VEGF receptor-2 (KDR) in human hemopoietic progenitor cells.
Topics: Active Transport, Cell Nucleus; Antigens, CD34; Cell Communication; Cell Nucleus; Culture Media; DNA-Binding Proteins; Female; Hematopoietic Stem Cells; Humans; Milk Proteins; Oligopeptides; Ovarian Neoplasms; Phosphorylation; Signal Transduction; STAT3 Transcription Factor; STAT5 Transcription Factor; Trans-Activators; Tyrosine; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2 | 2004 |
Tumor cells resistant to a microtubule-depolymerizing hemiasterlin analogue, HTI-286, have mutations in alpha- or beta-tubulin and increased microtubule stability.
Topics: Acetylation; Cell Line, Tumor; Cold Temperature; Dimerization; Drug Resistance, Neoplasm; Female; Growth Inhibitors; Humans; Microtubules; Mutation; Oligopeptides; Ovarian Neoplasms; Paclitaxel; Protein Structure, Secondary; Protein Structure, Tertiary; Tubulin; Tyrosine | 2004 |
Resveratrol causes Cdc2-tyr15 phosphorylation via ATM/ATR-Chk1/2-Cdc25C pathway as a central mechanism for S phase arrest in human ovarian carcinoma Ovcar-3 cells.
Topics: Antineoplastic Agents, Phytogenic; Ataxia Telangiectasia; Ataxia Telangiectasia Mutated Proteins; CDC2 Protein Kinase; cdc25 Phosphatases; Cell Cycle Proteins; Checkpoint Kinase 1; Checkpoint Kinase 2; DNA-Binding Proteins; Female; Humans; Ovarian Neoplasms; Phosphorylation; Protein Kinases; Protein Serine-Threonine Kinases; Resveratrol; Ribonucleotide Reductases; S Phase; Signal Transduction; Stilbenes; Tumor Cells, Cultured; Tumor Suppressor Proteins; Tyrosine | 2005 |
A constitutively active ERBB4/HER4 allele with enhanced transcriptional coactivation and cell-killing activities.
Topics: Alleles; Apoptosis; Breast Neoplasms; Caseins; Cell Nucleus; Cells, Cultured; ErbB Receptors; Female; Gene Expression Regulation, Neoplastic; Humans; Kidney; Male; Ovarian Neoplasms; Phosphorylation; Promoter Regions, Genetic; Prostatic Neoplasms; Protein Transport; Receptor, ErbB-4; STAT5 Transcription Factor; Transcription, Genetic; Transcriptional Activation; Tumor Suppressor Proteins; Tyrosine | 2007 |
Phosphorylation of glycogen synthase kinase-3 beta at serine 9 confers cisplatin resistance in ovarian cancer cells.
Topics: Apoptosis; Cell Line, Tumor; Cell Survival; Cisplatin; Drug Resistance, Neoplasm; Female; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Inhibitory Concentration 50; Ovarian Neoplasms; Phosphorylation; Serine; Transfection; Tumor Suppressor Protein p53; Tyrosine | 2007 |
HER4 expression correlates with cytotoxicity directed by a heregulin-toxin fusion protein.
Topics: ADP Ribose Transferases; Amino Acid Sequence; Animals; Bacterial Toxins; Base Sequence; Breast Neoplasms; Cell Line; Cell Survival; DNA Primers; ErbB Receptors; Exotoxins; Female; Gene Expression; Glycoproteins; Humans; Immunotoxins; Kidney; Kinetics; Leukemia, T-Cell; Lung Neoplasms; Male; Molecular Sequence Data; Neuregulins; Ovarian Neoplasms; Phosphorylation; Phosphotyrosine; Polymerase Chain Reaction; Prostatic Neoplasms; Pseudomonas aeruginosa; Pseudomonas aeruginosa Exotoxin A; Rats; Receptor, ErbB-4; Recombinant Fusion Proteins; RNA, Messenger; Tumor Cells, Cultured; Tyrosine; Virulence Factors | 1995 |
Lysophospholipids activate ovarian and breast cancer cells.
Topics: Breast Neoplasms; Calcium; Cell Division; Female; Humans; Lysophospholipids; Ovarian Neoplasms; Phosphorylation; Protein Kinases; Receptors, Cell Surface; Substrate Specificity; Tumor Cells, Cultured; Tyrosine | 1995 |
Immunohistochemistry of phosphotyrosine residues: identification of distinct intracellular patterns in epithelial and steroidogenic tissues.
Topics: Adrenal Glands; Animals; Antibodies, Monoclonal; Brain Chemistry; Endometrium; Epithelium; Female; Humans; Immunoenzyme Techniques; Male; Mice; Mice, Inbred C57BL; Ovarian Neoplasms; Ovary; Phosphotyrosine; Rats; Testis; Tyrosine | 1993 |
Association of inhibition of cell growth by O-phospho-L-tyrosine with decreased tyrosine phosphorylation.
Topics: 3T3 Cells; Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Division; Drug Interactions; Female; Humans; Insulin; Liver Neoplasms; Mice; Neoplasm Proteins; Neoplasms; Ovarian Neoplasms; Phosphorylation; Phosphotyrosine; Proto-Oncogene Proteins pp60(c-src); Receptor, ErbB-2; Receptor, Insulin; Tumor Cells, Cultured; Tyrosine | 1996 |
Characterization of the major metabolite of the novel topoisomerase I inhibitor NU/ICRF 505.
Topics: Animals; Anthraquinones; Antineoplastic Agents; Biotransformation; Carcinoma, Non-Small-Cell Lung; Cell Division; Cell Line; Chromatography, High Pressure Liquid; Colonic Neoplasms; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Female; Humans; Liver; Lung Neoplasms; Mice; Mice, Nude; Molecular Structure; Ovarian Neoplasms; Spectrometry, Mass, Fast Atom Bombardment; Topoisomerase I Inhibitors; Transplantation, Heterologous; Tyrosine | 1996 |
Integrin-mediated adhesion and signalling in ovarian cancer cells.
Topics: Antigens, CD; Calcium-Calmodulin-Dependent Protein Kinases; Cell Adhesion; Cell Adhesion Molecules; Female; Fluorescent Antibody Technique, Indirect; Humans; Integrin alpha2; Integrin alpha3; Integrin beta1; Integrins; Ovarian Neoplasms; Phosphorylation; Signal Transduction; Tumor Cells, Cultured; Tyrosine | 1998 |
Alterations in expression and function of signal-transducing proteins in tumor-associated T and natural killer cells in patients with ovarian carcinoma.
Topics: Aged; Aged, 80 and over; Female; Humans; Killer Cells, Natural; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Lymphocytes, Tumor-Infiltrating; Membrane Proteins; Middle Aged; Ovarian Neoplasms; Phosphorylation; Receptors, Antigen, T-Cell; Receptors, IgE; Receptors, IgG; Signal Transduction; Type C Phospholipases; Tyrosine | 1996 |
Characteristics of EGFR family-mediated HRG signals in human ovarian cancer.
Topics: DNA Replication; Enzyme Activation; ErbB Receptors; Female; Humans; Mitogen-Activated Protein Kinases; Neuregulin-1; Ovarian Neoplasms; Phosphorylation; Receptor, ErbB-2; Receptor, ErbB-3; Receptor, ErbB-4; Signal Transduction; Tumor Cells, Cultured; Tyrosine | 1999 |
Phosphorylation of the cytoplasmic domain of the MUC1 mucin correlates with changes in cell-cell adhesion.
Topics: Breast Neoplasms; Buffers; Cell Adhesion; Culture Media, Conditioned; Cytoplasm; Detergents; Female; Humans; Mucin-1; Ovarian Neoplasms; Phosphorylation; Precipitin Tests; Protein Isoforms; Protein Structure, Tertiary; Tumor Cells, Cultured; Tyrosine | 2000 |
Transactivation of the epidermal growth factor receptor in endothelin-1-induced mitogenic signaling in human ovarian carcinoma cells.
Topics: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Cell Division; Endothelin Receptor Antagonists; Endothelin-1; Enzyme Activation; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Female; GRB2 Adaptor Protein; Humans; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Ovarian Neoplasms; Peptides, Cyclic; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase C; Proteins; Quinazolines; Receptor, Endothelin A; Shc Signaling Adaptor Proteins; Src Homology 2 Domain-Containing, Transforming Protein 1; Transcriptional Activation; Tumor Cells, Cultured; Tyrosine; Tyrphostins | 2000 |
CD44 interaction with c-Src kinase promotes cortactin-mediated cytoskeleton function and hyaluronic acid-dependent ovarian tumor cell migration.
Topics: Animals; Cell Movement; Cloning, Molecular; Cortactin; Cytoskeleton; DNA, Complementary; Female; Genes, Dominant; Humans; Hyaluronan Receptors; Hyaluronic Acid; Immunoblotting; Microfilament Proteins; Microscopy, Fluorescence; Mutation; Ovarian Neoplasms; Phenotype; Phosphorylation; Plasmids; Precipitin Tests; Protein Binding; Protein Structure, Tertiary; Proto-Oncogene Proteins pp60(c-src); Rats; Recombinant Proteins; Time Factors; Transfection; Tumor Cells, Cultured; Tyrosine | 2001 |
The activated macrophage colony-stimulating factor (CSF-1) receptor as a predictor of poor outcome in advanced epithelial ovarian carcinoma.
Topics: Antibodies; Disease-Free Survival; Epithelial Cells; Female; Humans; Immunohistochemistry; Macrophage Colony-Stimulating Factor; Middle Aged; Ovarian Neoplasms; Phosphorylation; Predictive Value of Tests; Receptor, Macrophage Colony-Stimulating Factor; Staining and Labeling; Stromal Cells; Survival Rate; Tyrosine | 2001 |
The microsomal epoxide hydrolase Tyr113His polymorphism: association with risk of ovarian cancer.
Topics: Adult; Aged; Base Sequence; Case-Control Studies; DNA Primers; Epoxide Hydrolases; Female; Genotype; Histidine; Humans; Microsomes; Middle Aged; Ovarian Neoplasms; Polymorphism, Genetic; Tyrosine | 2001 |
Ovarian epithelial carcinoma tyrosine phosphorylation, cell proliferation, and ezrin translocation are stimulated by interleukin 1alpha and epidermal growth factor.
Topics: Blotting, Western; Carcinoma; Cell Division; Cytoskeletal Proteins; Epidermal Growth Factor; Female; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Interleukin-1; Neoplasm Invasiveness; Neoplasm Metastasis; Ovarian Neoplasms; Phenotype; Phosphoproteins; Phosphorylation; Translocation, Genetic; Tumor Cells, Cultured; Tyrosine | 2001 |
Tyrosine phosphatase inhibition permits analysis of signal transduction complexes in p185HER2/neu-overexpressing human tumor cells.
Topics: Amino Acid Sequence; Blotting, Western; Breast Neoplasms; Enzyme Activation; Female; Gene Expression; GTPase-Activating Proteins; Humans; Ovarian Neoplasms; Phosphorylation; Precipitin Tests; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Receptor, ErbB-2; Signal Transduction; Substrate Specificity; Tumor Cells, Cultured; Type C Phospholipases; Tyrosine | 1992 |
Effects of synthetic peptides and protease inhibitors on the interaction of a human ovarian cancer cell line (NIH:OVCAR-3) with a reconstituted basement membrane (Matrigel).
Topics: Amides; Amino Acid Sequence; Aminocaproates; Antineoplastic Agents; Benzamidines; Biocompatible Materials; Cell Adhesion; Cell Line; Chemotaxis; Collagen; Dose-Response Relationship, Drug; Drug Combinations; Female; Glycoproteins; Humans; In Vitro Techniques; Laminin; Leupeptins; Metalloendopeptidases; Molecular Sequence Data; Neoplasm Invasiveness; Oligopeptides; Ovarian Neoplasms; Pepstatins; Polyamines; Protease Inhibitors; Proteoglycans; Tissue Inhibitor of Metalloproteinases; Tumor Cells, Cultured; Tyrosine | 1991 |
Ganglioside-mediated modulation of cell growth. Specific effects of GM3 on tyrosine phosphorylation of the epidermal growth factor receptor.
Topics: Amino Acids; Animals; Carcinoma, Squamous Cell; Cattle; Cell Division; Cell Line; Depression, Chemical; Dogs; Epidermal Growth Factor; ErbB Receptors; Female; Fibroblasts; G(M1) Ganglioside; G(M3) Ganglioside; Gangliosides; Humans; Immunosorbent Techniques; Mice; Mouth Neoplasms; Ovarian Neoplasms; Phosphorylation; Phosphotyrosine; Receptors, Cell Surface; Tyrosine | 1986 |
Tumor response to phenylalanine-tyrosine-limited diets.
Topics: Adenocarcinoma; Amino Acids; Animals; Carcinoma, Hepatocellular; Cystadenoma; Deficiency Diseases; Diet Therapy; Female; Humans; Liver Neoplasms; Mammary Neoplasms, Experimental; Mice; Middle Aged; Neoplasms, Experimental; Ovarian Neoplasms; Phenylalanine; Sarcoma, Experimental; Tyrosine | 1969 |
[The effect of thyroid hormone on tumor cells in a tissue culture].
Topics: Animals; Culture Techniques; Diiodotyrosine; Embryo, Mammalian; Female; Humans; Mitosis; Ovarian Neoplasms; Pancreatic Neoplasms; Pregnancy; Rabbits; Thyroid Hormones; Tyrosine | 1968 |