tyrosine has been researched along with Osteosarcoma in 30 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (13.33) | 18.7374 |
| 1990's | 15 (50.00) | 18.2507 |
| 2000's | 7 (23.33) | 29.6817 |
| 2010's | 2 (6.67) | 24.3611 |
| 2020's | 2 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Collier, CD; Getty, PJ; Greenfield, EM | 1 |
| Kamptner, AZM; Stütz, A; Sutterlüty, H | 1 |
| Bazureau, JP; Carreaux, F; Chicanne, G; Durieu, E; Fant, X; Limanton, E; Meijer, L; Payrastre, B; Sbrissa, D; Shisheva, A | 1 |
| Furukawa, K; Hamamura, K; Hattori, H; Hotta, H; Matsumoto, Y; Nishida, Y; Shibuya, H; Ueda, M | 1 |
| Agapova, LS; Chumakov, PM; Kopnin, BP; Volodina, JL | 1 |
| Brunetto, A; Burguera, B; Couce, ME; Esplen, J; Garcia-Ocana, A; Teijeiro, R; Thomas, T; Zhao, A | 1 |
| Bhat, RA; Bodine, PV; Komm, BS; Stauffer, B | 1 |
| Bertolone, SJ; Clark, LW; Hilton, MA; Kmetz, DR; Patel, CC | 1 |
| Harris, S; Lopaczynski, W; Nissley, P | 1 |
| Graves, DT; Kang, YM; Yeh, YL | 1 |
| Farley, JR; Hall, SL; Lau, KH; Nicolas, V; Thomas, A | 1 |
| Catherwood, BD; Marzilli, LG; Nanes, MS; Rubin, J; Titus, L | 1 |
| Falnes, PO; Klingenberg, O; Muñoz, R; Olsnes, S; Rapak, A; Wiedłocha, A | 1 |
| Baron, R; Horowitz, MC; Levy, DE; Levy, JB; Raz, R; Schindler, C | 1 |
| Bruland, OS; Olafsen, T; Sandlie, I; Zalutsky, MR | 1 |
| Netelenbos, JC; Salles, JP; Slootweg, MC | 1 |
| Hamaguchi, M; Hayakawa, T; Iwata, H; Koike, T; Noguchi, T; Shinagawa, A; Suzuki, M; Yamashita, K | 1 |
| Eanes, ED; Fisher, LW; Mintz, KP; Stubbs, JT; Torchia, DA | 1 |
| Kley, N; LeRoith, D; Ohlsson, C; Werner, H | 1 |
| Auron, PE; Bavelloni, A; Cenni, V; Faenza, I; Ferri, A; Koyama, Y; Maraldi, NM; Marmiroli, S; Ognibene, A; Ruzzene, M; Sirri, A; Toker, A; Tsukada, J | 1 |
| Inoue, A; Komiya, S; Ohtsubo, M; Ohtsuka, S; Sakamoto, H; Sasaki, A; Valius, M; Wakioka, T; Yasukawa, H; Yokouchi, M; Yoshimura, A | 1 |
| Burns, DM; Kawase, T; Oguro, A; Orikasa, M | 1 |
| Kreutzfeld, R; Preuss, U; Scheidtmann, KH | 1 |
| Balzarini, J; De Clercq, E; Degrève, B; Esnouf, R | 1 |
| Harimaya, K; Iwamoto, Y; Matsuda, S; Matsumoto, Y; Nakatani, F; Tanaka, K | 1 |
| Hashimoto, H; Lau, KH | 1 |
| Benham, KJ; Fisher, LW; Hascall, VC; McQuillan, DJ; Midura, RJ | 1 |
| Bishayee, S; Frick, K; Mitchell, CD; Ross, AH; Scher, CD; Womer, RB | 1 |
| Bertolone, S; Hilton, MA; Patel, CC | 1 |
| Hersh, EM; Ohno, R | 1 |
1 review(s) available for tyrosine and Osteosarcoma
| Article | Year |
|---|---|
Receptor Tyrosine Kinases in Osteosarcoma: 2019 Update.
Topics: Bone Neoplasms; Humans; Osteosarcoma; Protein-Tyrosine Kinases; Tyrosine | 2020 |
29 other study(ies) available for tyrosine and Osteosarcoma
| Article | Year |
|---|---|
A Sprouty4 Mutation Identified in Kallmann Syndrome Increases the Inhibitory Potency of the Protein towards FGF and Connected Processes.
Topics: Cell Line; Cell Line, Tumor; Cell Movement; Cell Proliferation; Epidermal Growth Factor; Fibroblast Growth Factor 2; Fibroblasts; Humans; Intracellular Signaling Peptides and Proteins; Kallmann Syndrome; Lung; MAP Kinase Signaling System; Mutation; Nerve Tissue Proteins; Osteosarcoma; Phosphorylation; Signal Transduction; Tyrosine | 2021 |
cdc-like/dual-specificity tyrosine phosphorylation-regulated kinases inhibitor leucettine L41 induces mTOR-dependent autophagy: implication for Alzheimer's disease.
Topics: Alzheimer Disease; Animals; Autophagy; Cell Line; Cell Line, Tumor; Dioxoles; Dyrk Kinases; Enzyme Inhibitors; Humans; Imidazoles; Mice; Microtubule-Associated Proteins; Osteosarcoma; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; TOR Serine-Threonine Kinases; Tyrosine | 2014 |
Enhancement of malignant properties of human osteosarcoma cells with disialyl gangliosides GD2/GD3.
Topics: Bone Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Crk-Associated Substrate Protein; Focal Adhesion Kinase 1; Gangliosides; Gene Expression; Gene Silencing; Humans; Osteosarcoma; Paxillin; Phosphorylation; Sialyltransferases; Signal Transduction; src-Family Kinases; Tyrosine | 2012 |
Activation of Ras-Ral pathway attenuates p53-independent DNA damage G2 checkpoint.
Topics: Blotting, Western; CDC2 Protein Kinase; Cell Line, Tumor; Cell Separation; Cyclin B; Cyclin B1; DNA; DNA Damage; Doxorubicin; Ethyl Methanesulfonate; Fibroblasts; Flow Cytometry; G1 Phase; G2 Phase; Genes, Dominant; Humans; Microscopy, Fluorescence; Mitosis; Mutation; Osteosarcoma; Phosphatidylinositol 3-Kinases; Phosphorylation; Precipitin Tests; ral Guanine Nucleotide Exchange Factor; ras Proteins; Retroviridae; Signal Transduction; Thymidine; Time Factors; Tumor Suppressor Protein p53; Tyrosine | 2004 |
Leptin increases proliferation of human steosarcoma cells through activation of PI(3)-K and MAPK pathways.
Topics: Bone and Bones; Cell Line, Tumor; Cell Proliferation; Enzyme Activation; Enzyme Inhibitors; Humans; Insulin Receptor Substrate Proteins; Leptin; MAP Kinase Signaling System; Osteosarcoma; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Signal Transduction; Tyrosine | 2006 |
Structure-function analysis of secreted frizzled-related protein-1 for its Wnt antagonist function.
Topics: Amino Acid Sequence; Amino Acid Substitution; Cell Line, Tumor; Conserved Sequence; Gene Deletion; Genes, Reporter; Humans; Intercellular Signaling Peptides and Proteins; Luciferases; Membrane Proteins; Molecular Sequence Data; Mutant Chimeric Proteins; Osteosarcoma; Plasmids; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Structure-Activity Relationship; Transfection; Tryptophan; Tyrosine; Wnt Proteins | 2007 |
Plasma phenylalanine: tyrosine ratios during high-dose methotrexate-citrovorum "rescue".
Topics: Adolescent; Bone Neoplasms; Child; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Leucovorin; Male; Methotrexate; Osteosarcoma; Phenylalanine; Time Factors; Tyrosine | 1982 |
Insulin-like growth factor-I (IGF-I) dependent phosphorylation of the IGF-I receptor in MG-63 cells.
Topics: Blotting, Western; Cell Line; Electrophoresis, Polyacrylamide Gel; Humans; Insulin-Like Growth Factor I; Kinetics; Molecular Weight; Osteosarcoma; Phosphates; Phosphoproteins; Phosphorus Radioisotopes; Phosphorylation; Phosphotyrosine; Receptor, IGF Type 1; Tumor Cells, Cultured; Tyrosine | 1993 |
Interleukin-1 modulates phosphorylation of proteins in human osteoblastic cells.
Topics: Bone Neoplasms; Bone Resorption; Cell Division; Electrophoresis, Polyacrylamide Gel; Epidermal Growth Factor; Fibroblast Growth Factor 2; Fibroblasts; Humans; Interleukin-1; Osteoblasts; Osteosarcoma; Phosphorylation; Platelet-Derived Growth Factor; Proteins; Receptors, Growth Factor; Receptors, Platelet-Derived Growth Factor; Signal Transduction; Tumor Cells, Cultured; Tyrosine | 1995 |
Calcitonin acutely increases tyrosyl-phosphorylation of proteins in human osteosarcoma (SaOS-2) cells.
Topics: Alkaline Phosphatase; Calcitonin; Cell Differentiation; Dose-Response Relationship, Drug; Humans; Osteoblasts; Osteosarcoma; Phosphorylation; Proteins; Time Factors; Tumor Cells, Cultured; Tyrosine | 1995 |
Rat osteoblasts and ROS 17/2.8 cells contain a similar protein tyrosine phosphatase.
Topics: Animals; Animals, Newborn; Cells, Cultured; Chromatography, Ion Exchange; Glutamates; Glutamic Acid; Hydrogen-Ion Concentration; Kinetics; Molecular Weight; Osteoblasts; Osteosarcoma; Phosphorylation; Polymers; Protein Tyrosine Phosphatases; Rats; Sodium Chloride; Temperature; Tumor Cells, Cultured; Tyrosine | 1993 |
Stimulation of proliferation of a human osteosarcoma cell line by exogenous acidic fibroblast growth factor requires both activation of receptor tyrosine kinase and growth factor internalization.
Topics: Cell Division; Cell Nucleus; DNA, Neoplasm; Enzyme Activation; Fibroblast Growth Factor 1; Humans; Osteosarcoma; Phosphorylation; Receptor Protein-Tyrosine Kinases; Receptors, Fibroblast Growth Factor; Recombinant Fusion Proteins; Signal Transduction; Transfection; Tumor Cells, Cultured; Tyrosine | 1996 |
Activation of the JAK-STAT signal transduction pathway by oncostatin-M cultured human and mouse osteoblastic cells.
Topics: Animals; Cells, Cultured; Cytokines; DNA-Binding Proteins; Humans; Interferon-Stimulated Gene Factor 3; Janus Kinase 1; Janus Kinase 2; Mice; Mice, Inbred C57BL; Oncostatin M; Osteoblasts; Osteosarcoma; Peptides; Phosphorylation; Protein-Tyrosine Kinases; Proteins; Proto-Oncogene Proteins; Signal Transduction; STAT3 Transcription Factor; Trans-Activators; Transcription Factors; Tumor Cells, Cultured; TYK2 Kinase; Tyrosine | 1996 |
Abundant tyrosine residues in the antigen binding site in anti-osteosarcoma monoclonal antibodies TP-1 and TP-3: Application to radiolabeling.
Topics: Amino Acid Sequence; Antibodies, Monoclonal; Antibodies, Neoplasm; Antigens, Neoplasm; Binding Sites, Antibody; Cloning, Molecular; Genes, Immunoglobulin; Humans; Immunoconjugates; Immunoglobulin Fragments; Immunoglobulin Variable Region; Iodine Radioisotopes; Molecular Sequence Data; Osteosarcoma; Radionuclide Imaging; Tyrosine | 1996 |
Growth hormone induces tyrosine phosphorylation of annexin I in rat osteosarcoma cells.
Topics: Animals; Annexin A1; Human Growth Hormone; Humans; Osteosarcoma; Phosphorylation; Rats; Recombinant Proteins; Time Factors; Tumor Cells, Cultured; Tyrosine | 1996 |
Tyrosine phosphorylation is crucial for growth signaling by tissue inhibitors of metalloproteinases (TIMP-1 and TIMP-2).
Topics: Benzoquinones; Calcium-Calmodulin-Dependent Protein Kinases; DNA; Enzyme Activation; Genistein; Glycoproteins; Humans; Hydroquinones; Isoflavones; Lactams, Macrocyclic; Mitogen-Activated Protein Kinase 1; Osteosarcoma; Phosphorylation; Protease Inhibitors; Protein-Tyrosine Kinases; Proteins; Quinones; Rifabutin; Signal Transduction; Thymidine; Time Factors; Tissue Inhibitor of Metalloproteinase-2; Tissue Inhibitor of Metalloproteinases; Tritium; Tumor Cells, Cultured; Tyrosine | 1996 |
Characterization of native and recombinant bone sialoprotein: delineation of the mineral-binding and cell adhesion domains and structural analysis of the RGD domain.
Topics: Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Bone Neoplasms; Cell Adhesion; Cell Adhesion Molecules; Crystallization; Humans; Hydroxyapatites; Integrin-Binding Sialoprotein; Integrins; Isoelectric Point; Magnetic Resonance Spectroscopy; Membrane Proteins; Mice; Molecular Sequence Data; Oligopeptides; Osteosarcoma; Polymerase Chain Reaction; Protein Processing, Post-Translational; Rats; Recombinant Proteins; Sialoglycoproteins; Tumor Cells, Cultured; Tyrosine | 1997 |
p53 regulates insulin-like growth factor-I (IGF-I) receptor expression and IGF-I-induced tyrosine phosphorylation in an osteosarcoma cell line: interaction between p53 and Sp1.
Topics: Humans; Insulin-Like Growth Factor I; Mutation; Osteosarcoma; Phosphorylation; Promoter Regions, Genetic; Receptor, IGF Type 1; Sp1 Transcription Factor; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Tyrosine | 1998 |
Phosphatidylinositol 3-kinase is recruited to a specific site in the activated IL-1 receptor I.
Topics: Binding Sites; Consensus Sequence; Enzyme Activation; Humans; Interleukin-1; NF-kappa B; Osteosarcoma; Phosphatidylinositol 3-Kinases; Phosphorylation; Phosphotyrosine; Precipitin Tests; Protein Binding; Receptors, Interleukin-1; Receptors, Interleukin-1 Type I; src Homology Domains; Transcriptional Activation; Transfection; Tumor Cells, Cultured; Tyrosine | 1998 |
APS, an adaptor protein containing PH and SH2 domains, is associated with the PDGF receptor and c-Cbl and inhibits PDGF-induced mitogenesis.
Topics: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Blood Proteins; Cell Division; Gene Expression; Humans; Mitogens; Osteosarcoma; Phosphoproteins; Phosphorylation; Platelet-Derived Growth Factor; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-cbl; Receptors, Platelet-Derived Growth Factor; src Homology Domains; Tumor Cells, Cultured; Tyrosine; Ubiquitin-Protein Ligases | 1999 |
Possible regulation of epidermal growth factor-receptor tyrosine autophosphorylation by calcium and G proteins in chemically permeabilized rat UMR106 cells.
Topics: Adenosine Triphosphate; Animals; Calcium; Calcium Signaling; Carcinoma; Cell Membrane Permeability; Culture Media; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Genistein; GTP-Binding Proteins; Humans; Osteoblasts; Osteosarcoma; Phosphoproteins; Phosphorylation; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Rats; Signal Transduction; Time Factors; Tumor Cells, Cultured; Tyrosine; Vanadates | 1999 |
Tumor-derived p53 mutant C174Y is a gain-of-function mutant which activates the fos promoter and enhances colony formation.
Topics: Amino Acid Substitution; Animals; Antigens, Polyomavirus Transforming; Brain Neoplasms; Colony-Forming Units Assay; Cysteine; Genes, fos; Genes, p53; Genes, Reporter; Humans; Mutagenesis, Site-Directed; Osteosarcoma; Point Mutation; Promoter Regions, Genetic; Rats; Recombinant Proteins; Transcription, Genetic; Transcriptional Activation; Transfection; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Tyrosine | 2000 |
Selective abolishment of pyrimidine nucleoside kinase activity of herpes simplex virus type 1 thymidine kinase by mutation of alanine-167 to tyrosine.
Topics: Alanine; Amino Acid Substitution; Antiviral Agents; Bone Neoplasms; Cell Division; Ganciclovir; Herpesvirus 1, Human; Humans; Osteosarcoma; Phosphorylation; Point Mutation; Purine Nucleosides; Pyrimidine Nucleosides; Thymidine Kinase; Transduction, Genetic; Tumor Cells, Cultured; Tyrosine | 2000 |
Small GTP-binding protein, Rho, both increased and decreased cellular motility, activation of matrix metalloproteinase 2 and invasion of human osteosarcoma cells.
Topics: Actins; Amides; Bone Neoplasms; Cell Adhesion; Cell Movement; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Extracellular Matrix; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Humans; Intracellular Signaling Peptides and Proteins; Lysophospholipids; Matrix Metalloproteinase 2; Matrix Metalloproteinases, Membrane-Associated; Metalloendopeptidases; Osteosarcoma; Phosphorylation; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Pyridines; rho GTP-Binding Proteins; rho-Associated Kinases; RNA, Messenger; Tissue Inhibitor of Metalloproteinase-2; Tyrosine | 2001 |
Differential effects of bacterial toxins on mitogenic actions of sodium fluoride and those of aluminum fluoride in human TE85 osteosarcoma cells.
Topics: Alkaline Phosphatase; Aluminum Compounds; Bone Neoplasms; Cell Division; Cholera Toxin; Fluorides; Humans; Mitogen-Activated Protein Kinases; Mitogens; Osteosarcoma; Pertussis Toxin; Phosphorylation; Signal Transduction; Sodium Fluoride; Thymidine; Tumor Cells, Cultured; Tyrosine; Virulence Factors, Bordetella | 2001 |
A rat osteogenic cell line (UMR 106-01) synthesizes a highly sulfated form of bone sialoprotein.
Topics: Animals; Cell Line; Chromatography, Gel; Glucosamine; Osteopontin; Osteosarcoma; Rats; Sialoglycoproteins; Sulfates; Sulfur Radioisotopes; Tritium; Tyrosine | 1990 |
PDGF induces c-myc mRNA expression in MG-63 human osteosarcoma cells but does not stimulate cell replication.
Topics: Animals; Cell Division; Cell Line; DNA Replication; Humans; Insulin-Like Growth Factor I; Mice; Mice, Inbred BALB C; Mitosis; Oncogenes; Osteosarcoma; Phosphorylation; Phosphotyrosine; Platelet-Derived Growth Factor; Receptors, Cell Surface; Receptors, Platelet-Derived Growth Factor; RNA, Messenger; Tyrosine | 1987 |
Daily profiles of plasma phenylalanine and tyrosine in patients with osteogenic sarcoma during treatment with high-dose methotrexate-citrovorum rescue.
Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Child; Combined Modality Therapy; Female; Humans; Leg; Leucovorin; Male; Methotrexate; Osteosarcoma; Phenylalanine; Time Factors; Tyrosine | 1989 |
Immunosuppressive effects of L-asparaginase.
Topics: Adrenal Gland Neoplasms; Adult; Aged; Alanine; Antibody Formation; Antigens; Asparaginase; Asparagine; Breast Neoplasms; Carcinoma; Child, Preschool; Female; Glutamates; Hemocyanins; Humans; Hypersensitivity, Delayed; Immunoglobulins; Immunosuppressive Agents; Lectins; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Lymphocytes; Lysine; Male; Middle Aged; Neoplasms; Osteosarcoma; Tyrosine | 1970 |