tyrosine has been researched along with Obesity in 140 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (8.57) | 18.7374 |
| 1990's | 20 (14.29) | 18.2507 |
| 2000's | 56 (40.00) | 29.6817 |
| 2010's | 36 (25.71) | 24.3611 |
| 2020's | 16 (11.43) | 2.80 |
| Authors | Studies |
|---|---|
| Li, R; Qiao, J; Wang, S; Ye, Z; Zhang, C; Zhang, Y; Zhao, Y | 1 |
| Calderón-Torres, CM; Murguía-Romero, M; Ortiz-Reyes, AE | 1 |
| Bruno, RS; Dey, P; Sun, X; Zhu, J | 1 |
| Buzzetti, R; D'Onofrio, L; Maddaloni, E; Panimolle, F; Tiberti, C; Zampetti, S | 1 |
| Chen, S; Eguchi, M; Fukunaga, A; Kabe, I; Kochi, T; Miki, T; Mizoue, T; Nanri, A | 1 |
| Angot, B; Cormont, M; Cornejo, PJ; Gonzalez, T; Jager, J; Ohanna, M; Tanti, JF; Vergoni, B | 1 |
| Domínguez-Riscart, J; Durán-Ruiz, MC; González-Domínguez, Á; Lechuga-Sancho, AM; Mateos, RM; Saez-Benito, A; Visiedo, F | 1 |
| He, T; Liu, S; Wu, YY; Yang, YQ; Yang, ZY; Zhang, JH; Zhou, Y | 1 |
| Barr, D; Brady, MJ; Chellappa, SL; Garaulet, M; Heng, SW; Kerlin, K; Nedeltcheva, A; Piron, MJ; Qian, J; Scheer, FAJL; Shoji, B; Srivastav, S; Vujović, N; Wang, W | 1 |
| Ahmed, AR; Alexiadou, K; Bech, P; Bloom, SR; Camuzeaux, S; Clarke, RE; Cuenco, J; Khoo, B; Kowalka, AM; Lewis, MR; Minnion, J; Purkayastha, S; Romero, MG; Takats, Z; Tan, TM; Whitwell, HJ; Williams, EL | 1 |
| Bakhtyukov, AA; Derkach, KV; Kuznetsova, VS; Shpakov, AO; Sorokoumov, VN; Zakharova, IO | 1 |
| Dong, X; Feng, B; Liu, H; Liu, Z; Xu, Y; Zhang, J | 1 |
| Cester, AM; Ciavattini, A; Emanuelli, M; Lucarini, G; Mazzanti, L; Pompei, V; Sabbatinelli, J; Salvolini, E; Sartini, D; Vignini, A | 1 |
| Hang, J; Hou, E; Qiao, J; Zhao, Y | 1 |
| Bahnson, J; Bihlmeyer, N; Chen, H; Ilkayeva, O; Kwee, LC; Laferrère, B; Muehlbauer, MJ; Newgard, CB; Purnell, JQ; Shah, SH; Wolfe, B; Xavier Pi-Sunyer, F | 1 |
| Apryatin, SA; Balakina, AS; Gmoshinski, IV; Nikityuk, DB; Riger, NA; Shipelin, VA; Shumakova, AA; Trusov, NV | 1 |
| Apryatin, SA; Gmoshinski, IV; Mzhelskaya, KV; Nikityuk, DB; Riger, NA; Shipelin, VA; Shumakova, AA; Timonin, AN; Trusov, NV | 1 |
| Akbarpour, M; Gozal, D; Khalyfa, A; Maccari, R; Ottanà, R; Qiao, Z | 1 |
| Abate, ML; Bugianesi, E; Buzzigoli, E; Carli, F; Cassader, M; Ciociaro, D; Della Latta, V; Gaggini, M; Gambino, R; Gastaldelli, A; Marietti, M; Rosso, C | 1 |
| Astrup, A; Bendtsen, LQ; Bertram, HC; Gomes, S; Holst, JJ; Liaset, B; Reitelseder, S; Ritz, C; Schmedes, M; Sjödin, A; Sundekilde, UK; Young, JF | 1 |
| Guo, Z; Li, J; Man, F; Pan, Q; Wang, H; Wang, W; Xu, J; Yan, W; Zhou, Y | 1 |
| Bae, KH; Han, BS; Kim, JS; Kim, WK; Lee, EW; Lee, SC; Oh, KJ | 1 |
| Deubel, S; Grune, T; Höhn, A; Kehm, R; Rückriemen, J; Weber, D | 1 |
| Barba, P; Cline, GW; Febres, G; Harris, PE; Korner, J; Leibel, RL; Maffei, A; Rayat, GR; Slifstein, M | 1 |
| Liu, J; Lloyd, SG | 1 |
| Lam, L; Nakano, D; Nishiyama, A; Ortiz, RM; Peti-Peterdi, J; Popovich, I; Rodriguez, R; Sonanez-Organis, JG; Thorwald, MA; Vázquez-Medina, JP; Viscarra, JA | 1 |
| Christou, DD; English, M; Hwang, MH; Kim, HK; Luttrell, M; Meade, TH; Segal, MS; Yoo, JK | 1 |
| Didié, M; Gogiraju, R; Hasenfuss, G; Konstantinides, S; Leifheit-Nestler, M; Schäfer, K; Wagner, NM | 1 |
| Bhanot, S; Böhm, C; Dagnell, M; Kappert, K; Kintscher, U; Krüger, J; Meyborg, H; Ostman, A; Stawowy, P; Trappiel, M | 1 |
| Ceballos, GM; García, JR; Gutiérrez, L; Olivares, IM; Rincón, Mde J | 1 |
| Deng, J; Xiong, L; Zuo, Z | 1 |
| Aguila, MB; Barbosa-da-Silva, S; Magliano, DC; Mandarim-de-Lacerda, CA; Marinho, Tde S; Souza-Mello, V | 1 |
| Le, KJ; Lin, Q; Liu, JH; Liu, S; Lu, Y; Tang, SQ; Wang, XL; Yang, RL; Yin, S; Zheng, L; Zheng, ZX | 1 |
| Harper, MM; Holmes, A; Kardon, RH; Obrosov, A; Shevalye, H; Yorek, MA; Yorek, MS | 1 |
| Kim, J; Lee, H; Park, SD; Roh, JS; Shin, SS; Woo, S; Yoon, M | 1 |
| Breaux, C; Kruger, C; Nguyen, TT; Stadler, K; Wicks, SE | 1 |
| Aguirre, L; Aldámiz-Echevarría, L; Andrade, F; Arbones-Mainar, JM; Carpéné, C; Hasnaoui, M; Hijona, E; Llarena, M; Pérez-Matute, P; Portillo, MP; Villanueva-Millán, MJ | 1 |
| Harder, U; Hellmuth, C; Kirchberg, FF; Koletzko, B; Lass, N; Peissner, W; Reinehr, T | 1 |
| Kim, J; Lee, H; Lim, J; Shin, SS; Yang, H; Yoon, M; Yoon, S | 1 |
| Bachelard, H; Badeau, M; Bourgoin, F; Larivière, R; Mélançon, S; Nadeau, A; Pitre, M | 1 |
| Gonzalez, L; Jiang, L; Li, C; Li, W; Liu, Y; Wang, Q; Yang, G; You, J; Yu, X; Yu, Y | 1 |
| Heizer, AB; McLea, SA; Myatt, L; Richardson, JL; Roberts, VH; Smith, J | 1 |
| Carter, CB; Dearman, JA; Hester, RL; Hodnett, BL | 1 |
| Gletsu-Miller, N; Go, YM; Hansen, JM; Jones, DP; Lin, E; Torres, WE; Ziegler, TR | 1 |
| Beske, SD; Lawson, BR; Lesniewski, LA; Pierce, GL; Seals, DR | 1 |
| Higuchi, Y; Kashihara, N; Kobayashi, S; Kuwabara, A; Namikoshi, T; Nishijima, F; Sakuta, T; Satoh, M; Tomita, N | 1 |
| Cavallin, MA; Fadool, DA; Marks, DR; Mast, TG; Tucker, K | 1 |
| Abramsson-Zetterberg, L; Asgård, R; Basu, S; Johansson, C; Möller, L; Rytter, E; Sjödin, A; Vessby, B | 1 |
| Belza, A; Gille, MB; Kondrup, J; Schultz John, S | 1 |
| Dong, LQ; Fang, Q; Jia, W; Liu, F; Liu, M; Liu, X; Zhang, J; Zhou, L | 1 |
| Gonzalez, L; Jiang, L; Ke, Z; Li, C; Li, W; Liu, Y; Yang, G; You, J; Yu, X; Yu, Y | 1 |
| Chen, MS; Hou, N; Liu, SM; Luo, JD; Luo, MS; Sun, P; Xiao, Q; Zhang, GS; Zhang, HN | 1 |
| Jou, NT; Li, XY; Ma, SX; Smith, BT | 1 |
| Choi, KD; Chun, KH; Ciaraldi, TP; Henry, RR; Jung, Y; Kim, YB; Lee, DH | 1 |
| Charbonneau, A; Dallaire, P; Kapur, S; Marette, A; Perreault, M; Pilon, G; White, PJ | 1 |
| Bruno, RS; Chung, MY; Koo, SI; Manautou, JE; Park, HJ | 1 |
| Aicher, BO; Aponte, A; Cannon, RO; Chaudhry, H; Freeman, L; Gucek, M; Haser, E; Kato, GJ; Remaley, AT; Sethi, AA; Vazquez, E; Waclawiw, MA; Zalos, G | 1 |
| Bergheim, I; Breusing, N; Grimm, S; Grune, T; Kneschke, N; Weber, D | 1 |
| Adams, SH | 1 |
| Blough, ER; Kakarla, SK; Katta, A; Kolli, MB; Kundla, S; Manne, ND; Nalabotu, SK; Wu, M | 1 |
| Bodary, PF; Calo, S; Greenwald-Yarnell, M; IglayReger, HB; Johnson, JA; Myers, MG; Nair, L; Skorupski, J | 1 |
| Begieneman, MP; Bronzwaer, JG; Falcão-Pires, I; Hamdani, N; Laarman, GJ; Leite-Moreira, AF; Niessen, HW; Paulus, WJ; Somsen, A; Stienen, GJ; van der Velden, J; van Heerebeek, L; Verheugt, FW | 1 |
| Bidel, S; Carstensen, M; Erlund, I; Herder, C; Kempf, K; Koenig, W; Kuha, S; Martin, S; Roden, M; Sundvall, J; Tuomilehto, J | 1 |
| Bailey, CJ; Flatt, PR; Gault, VA; Greer, B; Harriott, P; Mooney, MH; O'harte, FP | 1 |
| Frisbee, JC; Maier, KG; Stepp, DW | 1 |
| Clampit, JE; Gaede, LL; Gum, RJ; Heindel, M; Jirousek, MR; Koterski, SL; Rondinone, CM; Trevillyan, JM; Ulrich, RG; Zinker, BA | 1 |
| Jacques, H; Lavigne, C; Marette, A; Tremblay, F | 1 |
| Ciaraldi, TP; Henry, RR; Kahn, BB; Kim, YB; Kotani, K | 1 |
| Acosta, PB; Bernstein, L; Chetty, M; DeVincentis, E; Gleason, S; Jurecki, E; Mofidi, S; Rouse, B; Singh, R; Steiner, R; Yannicelli, S | 1 |
| AKISAWA, J | 1 |
| Brodsky, SV; Chen, J; Crabtree, M; Gealekman, O; Goligorsky, MS; Gross, SS; Nasjletti, A; Togashi, N; Zhang, F | 1 |
| Carmiel-Haggai, M; Cederbaum, AI; Nieto, N | 1 |
| Myers, MG | 1 |
| Chen, MW; Liu, SQ; Sun, HY; Wang, CJ; Wang, YM; Xu, XP; Yang, MG; Zhang, Q | 1 |
| Barr, KJ; Erlanson, DA; Fahr, BJ; Hansen, SK; Kung, J; McDowell, RS; Randal, M; Shen, W; Taylor, L; Wiesmann, C; Zhong, M; Zhu, J | 1 |
| Brown, KK; Carrick, KM; Chen, L; Clifton, LG; McNulty, JA; Pahel, GL; Stimpson, SA; Strum, JC; Winegar, DA; Yang, B | 1 |
| Connie Hung, CC; Farooqi, IS; Gray, J; Keogh, J; O'Rahilly, S; Rochford, J; Sivaramakrishnan, S; Yeo, GS | 1 |
| Araújo, EP; Boschero, AC; De Souza, CT; Gasparetti, AL; Saad, MJ; Ueno, M; Velloso, LA | 1 |
| Kaduce, TL; Lee, HC; Spector, AA; Wang, XL; Zhou, W | 1 |
| Barreca, A; Johansen, T; Laurino, C; Malmlöf, K | 1 |
| Choi, JY; Jang, EH; Kang, JH; Park, CS | 1 |
| Gu, XF; Kuang, JQ; Wang, ZC; Yang, DZ | 1 |
| Belza, A; Jessen, AB | 1 |
| Bo, S; Cassader, M; Gambino, R; Gentile, L; Guidi, S; Pagani, A; Pagano, GF | 1 |
| Belfort, R; Berria, R; De Filippis, EA; Finlayson, J; Kashyap, S; Mandarino, LJ; Pratipanawatr, T; Richardson, DK; Wang, L | 1 |
| Li, Z; Ni, Z; Rodríguez-Iturbe, B; Sepassi, L; Shahkarami, A; Vaziri, ND | 1 |
| Carlson, EC; Esberg, LB; Fang, CX; Johnson, WT; Murphy, EJ; Relling, DP; Ren, J; Saari, JT | 1 |
| Gupte, A; Mora, S | 1 |
| Belza, A; Frandsen, E; Kondrup, J | 1 |
| Bujo, H; Hashimoto, N; Ishikawa, K; Saito, Y; Takahashi, K; Yagui, K | 1 |
| Guilford, BL; McClanahan, MW; Rector, RS; Sun, GY; Thomas, TR; Toedebusch, BW; Turk, JR | 1 |
| Bates, SH; Björnholm, M; Bjørbaek, C; Ishida-Takahashi, R; Jones, JC; Leshan, RL; Louis, GW; Münzberg, H; Myers, MG; Villanueva, EC | 1 |
| Cederbaum, AI; Dey, A | 1 |
| Haruna, Y; Kashihara, N; Kobayashi, S; Komai, N; Namikoshi, T; Sasaki, T; Satoh, M; Tomita, N | 1 |
| Coppey, LJ; Davidson, EP; Kleinschmidt, TL; Lund, DD; Oltman, CL; Yorek, MA | 1 |
| Dubé, N; Stuible, M; Tremblay, ML | 1 |
| Adams, SH; Bastard, JP; Buchman, VL; Clément, K; Dunn, TN; Grino, M; Knotts, TA; Luo, X; Naour, N; Ninkina, N; Oort, PJ; Pan, G; Permana, PA | 1 |
| Marchington, DR; Shargill, NS; York, DA | 1 |
| Freychet, P; Le Marchand-Brustel, Y; Monier, S | 1 |
| Ghadimi, H | 1 |
| Anderson, GH; Johnston, JL; Warsh, JJ | 1 |
| Budavari, A; Hotamisligil, GS; Murray, D; Spiegelman, BM | 1 |
| Carey, J; Dohm, GL; Giorgino, F; Goodyear, LJ; Sherman, LA; Smith, RJ | 1 |
| Livingston, JN; Moss, A; Moxley, RT; Unger, JW | 1 |
| Gautier, N; Heydrick, SJ; Le Marchand-Brustel, Y; Olichon-Berthe, C; Van Obberghen, E | 1 |
| Andersen, T; Astrup, A; Breum, L; Møller, SE | 1 |
| Abe, H; Chihara, K; Kaji, H; Mizuno, I; Okimura, Y; Takahashi, T; Takahashi, Y; Uchiyama, T | 1 |
| Chua, SC; Leibel, RL; Liu, SM; Nicolson, M; Okada, N; Wu-Peng, XS | 1 |
| Bjørbaek, C; da Silva, B; Flier, JS; Uotani, S | 1 |
| Matsutani, A; Oka, Y; Okuya, S; Tanabe, K; Tanizawa, Y | 1 |
| Christophe, J | 1 |
| Bjørbaek, C; da Silva, BA; Flier, JS; Uotani, S | 1 |
| Bryer-Ash, M; Cheung, AT; Coy, DH; Fuselier, J; Kolls, JK; Ree, D | 1 |
| Bedol, D; Ernsberger, P; Farrell, CJ; Friedman, JE; Ishizuka, T; Koletsky, RJ; Liu, S | 1 |
| Adkison, K; Binz, JG; Blanchard, SG; Brown, HR; Brown, KK; Cobb, JE; Faison, W; Harrington, WW; Hashim, MA; Henke, BR; Kaldor, I; Kliewer, SA; Lehmann, JM; Lenhard, JM; Menius, JA; Mook, R; Noble, SA; Novak, PJ; Oliver, WO; Parks, DJ; Plunket, KD; Tong, WQ; Willson, TM | 1 |
| Dohm, GL; Dolan, PL; Zhou, Q | 1 |
| Clemont, A; Feener, EP; Hein, KD; Igarashi, M; Jiang, ZY; King, GL; Lin, YW; White, MF; Yamauchi, T | 1 |
| Chen, J; Derouet, M; Dupont, J; Leclercq, B; Simon, J; Taouis, M | 1 |
| Palou, A; Proenza, AM; Roca, P | 1 |
| Carvalho, E; Rondinone, C; Smith, U | 1 |
| Bryer-Ash, M; Cheung, AT; Kolls, JK; Ree, D; Wang, J | 1 |
| Franke, TF; Kahn, BB; Kim, YB; Peroni, OD | 1 |
| Catalano, PM; Friedman, JE; Ishizuka, T; Shao, J; Yamashita, H | 1 |
| Apolinario, A; Fernández-Bermejo, M; García-Monzón, C; Iacono, OL; Larrañaga, E; Majano, PL; Martín-Pérez, E; Moreno-Otero, R | 1 |
| Barberà, A; Domínguez, J; Fernàndez-Alvarez, J; Gomis, R; Guinovart, JJ; Muñoz, MC | 1 |
| Brown, KK; Gottschalk, WK; Harrington, WW; Kliewer, SA; Mansfield, TA; Ramachandran, RK; Sundseth, SS; Way, JM; Willson, TM | 1 |
| Afzal, A; Aljada, A; Browne, R; Dandona, P; Garg, R; Ghanim, H; Hamouda, W; Mohanty, P; Prabhala, A | 1 |
| Brown, KK; Görgün, CZ; Harrington, WW; Hotamisligil, GS; Kliewer, SA; Oliver, WR; Tong, Q; Uysal, KT; Way, JM; Willson, TM | 1 |
| Aljada, A; Assian, E; Dandona, P; Garg, R; Ghanim, H; Hamouda, W; Mohanty, P | 1 |
| Chavey, C; Emanuelli, B; Filloux, C; Freidinger, K; Hilton, DJ; Hotamisligil, GS; Peraldi, P; Van Obberghen, E | 1 |
| Gu, Y; Li, J; Liu, Z; Su, J; Sun, F; Wang, Y; Wei, Q; Zhao, M; Zhu, M | 1 |
| Gerbeaux, J; Labrune, B; Tournier, G | 1 |
| Bagchi, N; Brown, TR; Dhar, A; Sheth, D; Sundick, RS | 1 |
| Ciaraldi, TP; Freidenberg, GR; Molina, JM; Olefsky, JM; Thies, RS | 1 |
| Brillon, DJ; Freidenberg, GR; Henry, RR; Olefsky, JM | 1 |
| Chan, CP; Hansen, RJ; Stern, JS | 1 |
| Bray, GA; Chopra, IJ; Melvin, KE | 1 |
| Banks, ME; Brown, ES; Colwell, RE; Gerritsen, T; Swanson, MA; Waisman, HA | 1 |
| Cavagnini, F; Litta Modignani, R | 1 |
| Cahill, GF; Felig, P; Marliss, E | 1 |
3 review(s) available for tyrosine and Obesity
| Article | Year |
|---|---|
Emerging perspectives on essential amino acid metabolism in obesity and the insulin-resistant state.
Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Amino Acids, Aromatic; Amino Acids, Sulfur; Animals; Cysteine; Cystine; Diabetes Mellitus, Type 2; Humans; Insulin Resistance; Methionine; Models, Biological; Obesity; Oxidation-Reduction; Oxidative Stress; Phenylalanine; Transaminases; Tyrosine | 2011 |
Leptin receptor signaling and the regulation of mammalian physiology.
Topics: Alternative Splicing; Animals; Energy Metabolism; Homeostasis; Humans; Hypothalamus; Janus Kinase 2; Leptin; Obesity; Phosphorylation; Protein Isoforms; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Receptors, Cell Surface; Receptors, Leptin; Signal Transduction; Tyrosine | 2004 |
[Pediatrics in 1976].
Topics: Adolescent; alpha 1-Antitrypsin Deficiency; Body Weight; Carcinoma, Hepatocellular; Catheterization; Child; Child, Preschool; Glycine max; Haemophilus Infections; Humans; Huntington Disease; Infant; Infant, Newborn; Levamisole; Liver Neoplasms; Malabsorption Syndromes; Mucocutaneous Lymph Node Syndrome; Nitrites; Obesity; Pediatrics; Pericarditis; Sepsis; Splenectomy; Tyrosine; Urinary Tract Infections | 1977 |
12 trial(s) available for tyrosine and Obesity
| Article | Year |
|---|---|
Late isocaloric eating increases hunger, decreases energy expenditure, and modifies metabolic pathways in adults with overweight and obesity.
Topics: Adult; Appetite; Eating; Energy Intake; Energy Metabolism; Ghrelin; Humans; Hunger; Leptin; Metabolic Networks and Pathways; Obesity; Overweight; p38 Mitogen-Activated Protein Kinases; Transforming Growth Factor beta; Tyrosine | 2022 |
Metabolites and diabetes remission after weight loss.
Topics: Amino Acids, Branched-Chain; Bariatric Surgery; Betaine; Biomarkers; Choline; Diabetes Mellitus, Type 2; Female; Humans; Male; Mass Spectrometry; Methylamines; Middle Aged; Obesity; Obesity, Morbid; Remission Induction; Treatment Outcome; Tyrosine; Weight Loss | 2021 |
The effect of casein, hydrolyzed casein, and whey proteins on urinary and postprandial plasma metabolites in overweight and moderately obese human subjects.
Topics: Adult; Caseins; Female; Humans; Isoleucine; Male; Obesity; Overweight; Plasma; Postprandial Period; Tyrosine; Urine; Whey Proteins; Young Adult | 2018 |
Mineralocorticoid receptors modulate vascular endothelial function in human obesity.
Topics: Abdominal Fat; Aged; Body Composition; Body Mass Index; Brachial Artery; Cross-Over Studies; Double-Blind Method; Endothelial Cells; Eplerenone; F2-Isoprostanes; Female; Humans; Male; Middle Aged; Mineralocorticoid Receptor Antagonists; NADPH Oxidases; Obesity; Oxidative Stress; Receptors, Mineralocorticoid; Spironolactone; Tyrosine; Ultrasonography | 2013 |
[Effect of a hypocaloric diet in the oxidative stress in obese subjects without prescription of exercise and antioxidants].
Topics: Adult; Anthropometry; Antioxidants; Biomarkers; Caloric Restriction; Combined Modality Therapy; Diet, Reducing; Exercise Therapy; Female; Humans; Male; Minerals; Obesity; Oxidative Stress; Protein Carbonylation; Thiobarbituric Acid Reactive Substances; Treatment Outcome; Tyrosine; Vitamins; Young Adult | 2015 |
Nuclear factor-{kappa}B activation contributes to vascular endothelial dysfunction via oxidative stress in overweight/obese middle-aged and older humans.
Topics: Administration, Oral; Aged; Aging; Anti-Inflammatory Agents, Non-Steroidal; Body Mass Index; Cross-Over Studies; Cyclooxygenase 1; Cyclooxygenase 2; Cytokines; Endothelium, Vascular; Female; Humans; I-kappa B Proteins; Male; Middle Aged; NADPH Oxidases; NF-kappa B; NF-KappaB Inhibitor alpha; Obesity; Overweight; Oxidative Stress; Salicylates; Tyrosine; Vasodilation | 2009 |
The beta-adrenergic antagonist propranolol partly abolishes thermogenic response to bioactive food ingredients.
Topics: Adrenergic beta-Antagonists; Adult; Basal Metabolism; Blood Pressure; Caffeine; Capsaicin; Catechin; Cross-Over Studies; Double-Blind Method; Heart Rate; Humans; Male; Obesity; Overweight; Propranolol; Thermogenesis; Tyrosine | 2009 |
Bioactive food stimulants of sympathetic activity: effect on 24-h energy expenditure and fat oxidation.
Topics: Adult; Caffeine; Calcium, Dietary; Calorimetry, Indirect; Capsaicin; Catechin; Central Nervous System Stimulants; Cross-Over Studies; Dietary Supplements; Double-Blind Method; Energy Metabolism; Heart Rate; Humans; Male; Obesity; Oxidation-Reduction; Plant Extracts; Respiration; Tea; Thermogenesis; Tyrosine | 2005 |
Body fat loss achieved by stimulation of thermogenesis by a combination of bioactive food ingredients: a placebo-controlled, double-blind 8-week intervention in obese subjects.
Topics: Adipose Tissue; Anti-Obesity Agents; Body Composition; Body Weight; Caffeine; Calcium, Dietary; Camellia sinensis; Capsaicin; Catechin; Dietary Fats; Dietary Supplements; Double-Blind Method; Energy Metabolism; Feces; Female; Humans; Male; Middle Aged; Obesity; Plant Extracts; Thermogenesis; Tyrosine; Weight Loss | 2007 |
Nuclear factor-kappaB suppressive and inhibitor-kappaB stimulatory effects of troglitazone in obese patients with type 2 diabetes: evidence of an antiinflammatory action?
Topics: Adult; Anti-Inflammatory Agents; Blood Glucose; C-Reactive Protein; Chemokine CCL2; Cholesterol; Chromans; Diabetes Mellitus; Diabetes Mellitus, Type 2; Female; Humans; I-kappa B Proteins; Insulin; Intercellular Adhesion Molecule-1; Leukocytes, Mononuclear; Linoleic Acid; Linoleic Acids; Linoleic Acids, Conjugated; Male; Middle Aged; NADPH Oxidases; Neutrophils; NF-kappa B; Obesity; Phenylalanine; Phosphoproteins; Plasminogen Activator Inhibitor 1; Reactive Oxygen Species; Thiazoles; Thiazolidinediones; Triglycerides; Troglitazone; Tyrosine | 2001 |
Insulin-receptor autophosphorylation and endogenous substrate phosphorylation in human adipocytes from control, obese, and NIDDM subjects.
Topics: Adipose Tissue; Adult; Animals; Biological Transport; Cell Fractionation; Diabetes Mellitus; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Glucose; Humans; Hydrogen Peroxide; Immunoblotting; Insulin; Insulin Resistance; Membrane Proteins; Obesity; Phosphorylation; Protein-Tyrosine Kinases; Rats; Rats, Inbred Strains; Receptor, Insulin; Temperature; Tyrosine; Vanadates; Wheat Germ Agglutinins | 1990 |
Effect of triiodothyronine on some metabolic responses of obese patients.
Topics: Adolescent; Adult; Blood Pressure; Body Height; Body Weight; Clinical Trials as Topic; Creatinine; Dietary Proteins; Female; Heart Rate; Humans; Iodine; Iodine Radioisotopes; Male; Middle Aged; Nitrogen; Obesity; Oxygen Consumption; Potassium; Sodium; Thyroid Function Tests; Thyroxine; Triiodothyronine; Tyrosine | 1973 |
125 other study(ies) available for tyrosine and Obesity
| Article | Year |
|---|---|
Amino acid signatures in relation to polycystic ovary syndrome and increased risk of different metabolic disturbances.
Topics: Alanine; Amino Acids; Body Mass Index; Female; Glycine; Humans; Insulin Resistance; Lysine; Metabolic Syndrome; Obesity; Polycystic Ovary Syndrome; Tyrosine | 2022 |
Oxidative Damage by 3-nitrotyrosine in Young Adults with Obesity: Its Implication in Chronic and Contagious Diseases.
Topics: Adolescent; Adult; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Male; Obesity; Oxidative Stress; Tyrosine; Young Adult | 2023 |
EGCG and catechin relative to green tea extract differentially modulate the gut microbial metabolome and liver metabolome to prevent obesity in mice fed a high-fat diet.
Topics: Animals; Antioxidants; Catechin; Diet, High-Fat; Gastrointestinal Microbiome; Liver; Male; Metabolome; Mice; Mice, Inbred C57BL; Obesity; Plant Extracts; Tea; Tyrosine | 2022 |
Immunoreactivities Against Different Tyrosine-Phosphatase 2 (IA-2)(256-760) Protein Domains Characterize Distinct Phenotypes in Subjects With LADA.
Topics: Autoantibodies; Diabetes Mellitus, Type 1; Epitopes; Humans; Immunity; Latent Autoimmune Diabetes in Adults; Obesity; Phenotype; Phosphoric Monoester Hydrolases; Protein Domains; Tyrosine | 2022 |
Associations of serum amino acids with insulin resistance among people with and without overweight or obesity: A prospective study in Japan.
Topics: Alanine; Animals; Humans; Insulin; Insulin Resistance; Isoleucine; Japan; Methionine; Obesity; Overweight; Prospective Studies; Thinness; Tyrosine; Valine | 2022 |
The Stress-Responsive microRNA-34a Alters Insulin Signaling and Actions in Adipocytes through Induction of the Tyrosine Phosphatase PTP1B.
Topics: Adipocytes; Animals; Insulin; Insulin Resistance; Mice; Mice, Obese; MicroRNAs; Obesity; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Tyrosine | 2022 |
Catalase post-translational modifications as key targets in the control of erythrocyte redox homeostasis in children with obesity and insulin resistance.
Topics: Antioxidants; Biotin; Catalase; Chromatography, Liquid; Erythrocytes; Homeostasis; Humans; Insulin Resistance; Nitric Oxide; Obesity; Oxidation-Reduction; Oxidative Stress; Protein Processing, Post-Translational; Reactive Oxygen Species; Tandem Mass Spectrometry; Tyrosine | 2022 |
N-linoleyltyrosine ameliorates high-fat diet-induced obesity in C57BL/6 mice
Topics: Animals; Diet, High-Fat; Glucose; Lipid Metabolism; Lipids; Mice; Mice, Inbred C57BL; Obesity; Triglycerides; Tyrosine | 2022 |
The postprandial secretion of peptide YY
Topics: Blood Glucose; Chromatography, Liquid; Gastrectomy; Gastric Bypass; Humans; Obesity; Peptide YY; Tandem Mass Spectrometry; Tyrosine | 2023 |
[Characterization and biological activity of new 4-oxo-1,4-dihydrocinnoline-based inhibitors of the tyrosine phosphatase PTP1B and TCPTP].
Topics: Animals; Enzyme Inhibitors; Glucose; Insulin; Insulin Resistance; Leptin; Obesity; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatase, Non-Receptor Type 2; Rats; Rats, Wistar; T-Lymphocytes; Tyrosine | 2022 |
Virtual Screening and Biological Evaluation of Novel Low Molecular Weight Protein Tyrosine Phosphatase Inhibitor for the Treatment of Insulin Resistance.
Topics: Enzyme Inhibitors; Humans; Insulin Resistance; Molecular Weight; Obesity; Phosphatidylinositol 3-Kinases; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatases; Tyrosine | 2023 |
Nitric oxide synthase and VEGF expression in full-term placentas of obese women.
Topics: Adult; Female; Humans; Immunohistochemistry; Nitric Oxide; Nitric Oxide Synthase; Obesity; Placenta; Pregnancy; Real-Time Polymerase Chain Reaction; Tyrosine; Vascular Endothelial Growth Factors | 2019 |
Metabolomics and correlation network analysis of follicular fluid reveals associations between l-tryptophan, l-tyrosine and polycystic ovary syndrome.
Topics: Adult; Female; Follicular Fluid; Gas Chromatography-Mass Spectrometry; Humans; Insulin Resistance; Metabolic Networks and Pathways; Metabolome; Metabolomics; Obesity; Polycystic Ovary Syndrome; Tryptophan; Tyrosine | 2021 |
Effects of Tyrosine and Tryptophan in Rats with Diet-Induced Obesity.
Topics: Animals; Body Weight; Cytokines; Diet; Energy Metabolism; Feeding Behavior; Inflammation; Liver; Male; Memory; Obesity; Rats; Rats, Wistar; Triglycerides; Tryptophan; Tyrosine | 2021 |
Effects of Tyrosine and Tryptophan Supplements on the Vital Indicators in Mice Differently Prone to Diet-Induced Obesity.
Topics: Animals; Diet, High-Fat; Dietary Supplements; Dopamine; Liver; Male; Mice; Mice, Inbred DBA; Obesity; Tryptophan; Tyrosine | 2021 |
Protein-Tyrosine Phosphatase-1B Mediates Sleep Fragmentation-Induced Insulin Resistance and Visceral Adipose Tissue Inflammation in Mice.
Topics: Adipose Tissue, White; Animals; Eating; Hypothalamus; Inflammation; Insulin; Insulin Resistance; Intra-Abdominal Fat; Leptin; Macrophages; Male; Metabolic Syndrome; Mice; Mice, Inbred C57BL; Obesity; Phosphorylation; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Receptor, Insulin; Signal Transduction; Sleep Deprivation; STAT3 Transcription Factor; Tyrosine; Weight Gain | 2017 |
Altered amino acid concentrations in NAFLD: Impact of obesity and insulin resistance.
Topics: Adult; Age Factors; Amino Acids; Biomarkers; Case-Control Studies; Disease Progression; Female; Glutamic Acid; Humans; Insulin Resistance; Isoleucine; Male; Middle Aged; Non-alcoholic Fatty Liver Disease; Obesity; Prognosis; Reference Values; Retrospective Studies; Risk Assessment; Severity of Illness Index; Sex Factors; Tyrosine | 2018 |
Sitagliptin Protects Cardiac Function by Reducing Nitroxidative Stress and Promoting Autophagy in Zucker Diabetic Fatty (ZDF) Rats.
Topics: Animals; Autophagy; Beclin-1; Blood Glucose; Cell Line; Diabetes Mellitus, Type 2; Diabetic Cardiomyopathies; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Disease Models, Animal; Humans; Lipids; Male; Myocytes, Cardiac; Nitrosative Stress; Obesity; Rats, Zucker; Sitagliptin Phosphate; Stroke Volume; Tyrosine; Ventricular Function, Left | 2018 |
Protein Tyrosine Phosphatase, Receptor Type B (PTPRB) Inhibits Brown Adipocyte Differentiation through Regulation of VEGFR2 Phosphorylation.
Topics: Adipocytes, Brown; Adipogenesis; Cell Differentiation; Cell Line; Diabetes Mellitus, Type 2; Gene Expression Regulation; Humans; NADH Dehydrogenase; Obesity; Phosphorylation; Receptor-Like Protein Tyrosine Phosphatases, Class 3; Tyrosine; Uncoupling Protein 1; Vascular Endothelial Growth Factor Receptor-2 | 2019 |
Endogenous advanced glycation end products in pancreatic islets after short-term carbohydrate intervention in obese, diabetes-prone mice.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Type 2; Diet, Carbohydrate-Restricted; Diet, High-Fat; Dietary Carbohydrates; Glycation End Products, Advanced; Hyperglycemia; Insulin; Insulin-Secreting Cells; Islets of Langerhans; Mice; Nitric Oxide Synthase Type II; Obesity; Tyrosine | 2019 |
A role for foregut tyrosine metabolism in glucose tolerance.
Topics: Animals; Aromatic-L-Amino-Acid Decarboxylases; Blood Glucose; Cell Line; Cross-Sectional Studies; Dopamine; Female; Gastrointestinal Tract; Glucose Tolerance Test; Homeostasis; Humans; Insulin; Insulin-Secreting Cells; Levodopa; Male; Nutrients; Obesity; Postprandial Period; Rats; Rats, Inbred Lew; Swine; Tyrosine; Tyrosine 3-Monooxygenase | 2019 |
High-fat, low-carbohydrate diet alters myocardial oxidative stress and impairs recovery of cardiac function after ischemia and reperfusion in obese rats.
Topics: Adiponectin; Animals; Antioxidants; Catalase; Diet, Carbohydrate-Restricted; Diet, High-Fat; DNA Copy Number Variations; DNA, Mitochondrial; Glycogen; Insulin; Male; Mitochondrial Turnover; Myocardial Reperfusion Injury; Myocardium; NADPH Oxidase 4; NADPH Oxidases; Obesity; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Superoxide Dismutase; Tyrosine; Weight Loss; Xanthine Oxidase | 2013 |
Angiotensin receptor-mediated oxidative stress is associated with impaired cardiac redox signaling and mitochondrial function in insulin-resistant rats.
Topics: Aldehydes; Angiotensin II Type 1 Receptor Blockers; Animals; Catalase; Citrate (si)-Synthase; Disease Models, Animal; Gene Expression Regulation, Enzymologic; Glutathione Peroxidase; Imidazoles; Insulin Resistance; Male; Membrane Glycoproteins; Mitochondria, Heart; Myocardium; NADPH Oxidase 2; NADPH Oxidase 4; NADPH Oxidases; NF-E2-Related Factor 2; Obesity; Oxidation-Reduction; Oxidative Stress; Rats; Rats, Inbred OLETF; Receptor, Angiotensin, Type 1; RNA, Messenger; Signal Transduction; Succinate Dehydrogenase; Superoxide Dismutase; Tetrazoles; Time Factors; Tyrosine | 2013 |
Importance of leptin signaling and signal transducer and activator of transcription-3 activation in mediating the cardiac hypertrophy associated with obesity.
Topics: Animals; Cardiomegaly; Echocardiography; Immunohistochemistry; Leptin; Mice; Mice, Transgenic; Mutation; Obesity; Phenotype; Receptors, Leptin; Serine; Signal Transduction; STAT3 Transcription Factor; Tyrosine | 2013 |
Targeting density-enhanced phosphatase-1 (DEP-1) with antisense oligonucleotides improves the metabolic phenotype in high-fat diet-fed mice.
Topics: Adipose Tissue; Animals; Cell Line; Diet, High-Fat; Insulin; Insulin Resistance; Liver; Male; Mice, Inbred C57BL; Muscle, Skeletal; Obesity; Oligonucleotides, Antisense; Organ Specificity; Phenotype; Phosphorylation; Receptor-Like Protein Tyrosine Phosphatases, Class 3; Receptor, Insulin; Signal Transduction; Tyrosine | 2013 |
Trans-sodium crocetinate provides neuroprotection against cerebral ischemia and reperfusion in obese mice.
Topics: Aldehydes; Analysis of Variance; Animals; Brain; Brain Ischemia; Carotenoids; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Matrix Metalloproteinases; Mice; Nervous System Diseases; Neuroprotective Agents; Obesity; Oxidative Stress; Reperfusion; Tyrosine; Vitamin A | 2015 |
Singular effects of PPAR agonists on nonalcoholic fatty liver disease of diet-induced obese mice.
Topics: Adipokines; Animals; Benzophenones; Blood Glucose; Body Weight; Diet, High-Fat; Energy Intake; Glucose Intolerance; Lipid Metabolism; Liver; Liver Cirrhosis; Male; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Obesity; PPAR alpha; Tyrosine | 2015 |
N-stearoyltyrosine dipotassium ameliorates high-fat diet-induced obesity in C57BL/6 mice.
Topics: Adiposity; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anti-Obesity Agents; Dietary Fats; Dose-Response Relationship, Drug; Drugs, Investigational; Duodenum; Gastrointestinal Agents; Intestinal Absorption; Intestinal Mucosa; Lipase; Lipogenesis; Lipolysis; Liver; Male; Mice, Inbred C57BL; Neuroprotective Agents; Obesity; Random Allocation; Tyrosine; Weight Gain | 2015 |
Effect of diet-induced obesity or type 1 or type 2 diabetes on corneal nerves and peripheral neuropathy in C57Bl/6J mice.
Topics: Aldehydes; Animals; Cornea; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Diet; Ganglia, Spinal; Glucose Tolerance Test; Mice; Mice, Inbred C57BL; Neural Conduction; Obesity; Tyrosine | 2015 |
Herbal composition Gambigyeongsinhwan (4) from Curcuma longa, Alnus japonica, and Massa Medicata Fermentata inhibits lipid accumulation in 3T3-L1 cells and regulates obesity in Otsuka Long-Evans Tokushima Fatty rats.
Topics: 3T3-L1 Cells; Alnus; Animals; Anti-Obesity Agents; CCAAT-Enhancer-Binding Proteins; Curcuma; Drugs, Chinese Herbal; Fatty Acid-Binding Proteins; Lipid Metabolism; Male; Medicine, Korean Traditional; Mice; Obesity; Oxazoles; Phytotherapy; Plant Extracts; Plant Preparations; PPAR alpha; PPAR gamma; Rats, Inbred OLETF; RNA, Messenger; Triglycerides; Tyrosine; Weight Gain | 2015 |
Diet-induced obesity and kidney disease - In search of a susceptible mouse model.
Topics: Animals; Diet; Disease Models, Animal; Insulin Resistance; Lipid Metabolism; Male; Mice; Mitochondria; Nitric Oxide Synthase Type II; Obesity; Oxidative Stress; Renal Insufficiency, Chronic; Tyrosine | 2016 |
Potential renoprotective effects of piceatannol in ameliorating the early-stage nephropathy associated with obesity in obese Zucker rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Biomarkers; Cell Adhesion Molecules; Dietary Supplements; Fibrosis; Kidney; Lipid Peroxidation; Male; Obesity; Organ Size; Oxidative Stress; Random Allocation; Rats, Zucker; Renal Insufficiency; Severity of Illness Index; Stilbenes; Thiobarbituric Acid Reactive Substances; Tyrosine | 2016 |
Tyrosine Is Associated with Insulin Resistance in Longitudinal Metabolomic Profiling of Obese Children.
Topics: Adolescent; Amino Acids, Branched-Chain; Child; Female; Glucose Tolerance Test; Humans; Insulin Resistance; Life Style; Male; Metabolomics; Obesity; Tyrosine | 2016 |
The effects of herbal composition Gambigyeongsinhwan (4) on hepatic steatosis and inflammation in Otsuka Long-Evans Tokushima fatty rats and HepG2 cells.
Topics: Alanine Transaminase; Animals; Anti-Inflammatory Agents; Biomarkers; Cytokines; Disease Models, Animal; Fenofibrate; Gene Expression Regulation, Enzymologic; Hep G2 Cells; Hepatitis; Hepatocytes; Humans; Hypolipidemic Agents; Inflammation Mediators; Lipids; Lipogenesis; Liver; Male; Mice; Non-alcoholic Fatty Liver Disease; Obesity; Oxazoles; Plant Extracts; PPAR alpha; Rats, Inbred OLETF; RNA, Messenger; Transfection; Tyrosine | 2017 |
Endothelial and vascular dysfunctions and insulin resistance in rats fed a high-fat, high-sucrose diet.
Topics: Animals; Blood Pressure; Blotting, Western; Body Weight; Deoxyglucose; Diet; Dietary Fats; Endothelin-1; Endothelium, Vascular; Fatty Acids, Nonesterified; Fluorescent Antibody Technique; Glucose Clamp Technique; Heart Rate; Insulin; Insulin Resistance; Male; Obesity; Organ Size; Rats; Rats, Sprague-Dawley; Sucrose; Triglycerides; Tyrosine; Vascular Diseases; Vascular Resistance | 2008 |
Tyrosine-dependent and -independent actions of leptin receptor in control of energy balance and glucose homeostasis.
Topics: Animals; Body Temperature Regulation; Energy Metabolism; Glucose; Homeostasis; Hypothalamus; Leptin; Mice; Mice, Inbred C57BL; Obesity; Receptors, Leptin; STAT3 Transcription Factor; Tyrosine | 2008 |
Effect of increasing maternal body mass index on oxidative and nitrative stress in the human placenta.
Topics: Adult; Biomarkers; Blotting, Western; Body Mass Index; Enzyme-Linked Immunosorbent Assay; Female; Humans; Immunohistochemistry; Obesity; Oxidative Stress; Placenta; Pregnancy; Protein Carbonylation; Reactive Nitrogen Species; Superoxide Dismutase; Thinness; Tyrosine; Young Adult | 2009 |
Attenuated PGI2 synthesis in obese Zucker rats.
Topics: Animals; Arachidonic Acid; Blotting, Western; Cell Separation; Epoprostenol; Fluorescent Antibody Technique; In Vitro Techniques; Male; Microcirculation; Myocytes, Smooth Muscle; Nitrates; Obesity; Physical Conditioning, Animal; Rats; Rats, Zucker; Receptors, Epoprostenol; Receptors, Thromboxane A2, Prostaglandin H2; Tyrosine | 2009 |
Loss of total and visceral adipose tissue mass predicts decreases in oxidative stress after weight-loss surgery.
Topics: Adipose Tissue; Adult; Bariatric Surgery; Body Mass Index; Body Weight; Female; Humans; Intra-Abdominal Fat; Lipid Peroxides; Lipoproteins, HDL; Longitudinal Studies; Middle Aged; Obesity; Oxidative Stress; Predictive Value of Tests; Reactive Oxygen Species; Subcutaneous Fat; Tyrosine; Weight Loss | 2009 |
Oral adsorbent AST-120 ameliorates endothelial dysfunction independent of renal function in rats with subtotal nephrectomy.
Topics: Acetylcholine; Animals; Aorta; Blotting, Western; Carbon; Cardiovascular Diseases; Endothelium, Vascular; Immunohistochemistry; Kidney; Kidney Function Tests; Male; NADPH Oxidases; Nephrectomy; Nitric Oxide Synthase Type III; Obesity; Oxidative Stress; Oxides; Phosphorylation; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; Tyrosine | 2009 |
Awake intranasal insulin delivery modifies protein complexes and alters memory, anxiety, and olfactory behaviors.
Topics: Administration, Intranasal; Animals; Animals, Newborn; Anxiety; Behavior, Animal; Blood Glucose; Brain Chemistry; Humans; Hypoglycemic Agents; Insulin; Kv1.3 Potassium Channel; Male; Memory; Mice; Mice, Inbred C57BL; Mice, Transgenic; Obesity; Olfactory Mucosa; Olfactory Pathways; Phosphorylation; Receptors, Odorant; Sensory Thresholds; Smell; tau Proteins; Time Factors; Tyrosine; Wakefulness | 2009 |
Glycaemic status in relation to oxidative stress and inflammation in well-controlled type 2 diabetes subjects.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Aged; Biomarkers; Blood Glucose; Body Mass Index; C-Reactive Protein; Deoxyguanosine; Diabetes Mellitus, Type 2; Dinoprost; Female; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Inflammation; Insulin; Interleukin-6; Lipids; Male; Malondialdehyde; Middle Aged; Obesity; Oxidative Stress; Probability; Statistics, Nonparametric; Tyrosine; Waist Circumference | 2009 |
Autophagy-mediated insulin receptor down-regulation contributes to endoplasmic reticulum stress-induced insulin resistance.
Topics: 3T3-L1 Cells; Adipocytes; Animals; Autophagy; Disease Models, Animal; Down-Regulation; Endoplasmic Reticulum; Humans; Insulin Resistance; Leupeptins; Mice; Mice, Inbred Strains; Obesity; Phosphorylation; Receptor, Insulin; Taurochenodeoxycholic Acid; Tyrosine | 2009 |
Signaling through Tyr985 of leptin receptor as an age/diet-dependent switch in the regulation of energy balance.
Topics: Aging; Animals; Diet; Dietary Fats; Eating; Energy Metabolism; Female; Gene Knock-In Techniques; Humans; Hypothalamus; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neuropeptides; Obesity; Receptors, Leptin; Signal Transduction; STAT3 Transcription Factor; Suppressor of Cytokine Signaling 3 Protein; Suppressor of Cytokine Signaling Proteins; Tyrosine | 2010 |
Leptin induces hypertrophy through activating the peroxisome proliferator-activated receptor α pathway in cultured neonatal rat cardiomyocytes.
Topics: Animals; Animals, Newborn; Blotting, Western; Cardiomegaly; Cell Culture Techniques; Cell Enlargement; Cells, Cultured; Dose-Response Relationship, Drug; Electrophoretic Mobility Shift Assay; Enzyme-Linked Immunosorbent Assay; Leptin; Myocytes, Cardiac; Obesity; Oxazoles; PPAR alpha; Protein Binding; Rats; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; Tyrosine | 2010 |
Changes in nitric oxide, cGMP, and nitrotyrosine concentrations over skin along the meridians in obese subjects.
Topics: Acupuncture Points; Adult; Cyclic GMP; Cyclic N-Oxides; Female; Humans; Imidazoles; Male; Nitrates; Nitric Oxide; Nitrites; Obesity; Skin; Tyrosine | 2011 |
In vivo activation of ROCK1 by insulin is impaired in skeletal muscle of humans with type 2 diabetes.
Topics: Actin Depolymerizing Factors; Adult; Biotransformation; Blotting, Western; Body Mass Index; Cytoskeletal Proteins; Diabetes Mellitus, Type 2; Female; Glucose; Glucose Clamp Technique; Humans; Hypoglycemic Agents; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Kinetics; Male; Middle Aged; Muscle, Skeletal; Obesity; Phosphorylation; rho GTP-Binding Proteins; rho-Associated Kinases; rhoA GTP-Binding Protein; Tyrosine | 2011 |
Endotoxin mediated-iNOS induction causes insulin resistance via ONOO⁻ induced tyrosine nitration of IRS-1 in skeletal muscle.
Topics: Animals; Endotoxemia; Endotoxins; Insulin Receptor Substrate Proteins; Insulin Resistance; Mice; Muscle, Skeletal; Nitric Oxide Synthase Type II; Nitrogen; Obesity; Peroxynitrous Acid; Phosphatidylinositol 3-Kinases; Rats; Sepsis; Signal Transduction; Tyrosine | 2010 |
Green tea extract protects against nonalcoholic steatohepatitis in ob/ob mice by decreasing oxidative and nitrative stress responses induced by proinflammatory enzymes.
Topics: Alanine Transaminase; Aldehydes; Animals; Anti-Inflammatory Agents; Fatty Liver; Inflammation; Lipid Peroxidation; Liver; Male; Mice; Mice, Inbred C57BL; Mice, Obese; NADPH Oxidases; Nitric Oxide Synthase Type II; Non-alcoholic Fatty Liver Disease; Obesity; Oxidative Stress; Peroxidase; Plant Extracts; Reactive Oxygen Species; Stress, Physiological; Tea; Tyrosine | 2012 |
High-density lipoprotein cholesterol efflux, nitration of apolipoprotein A-I, and endothelial function in obese women.
Topics: Adenosine Triphosphate; Adult; Aged; Apolipoprotein A-I; ATP-Binding Cassette Transporters; Blood Pressure; Body Mass Index; Brachial Artery; Cholesterol, HDL; Endothelium, Vascular; Female; Humans; Middle Aged; Obesity; Regression Analysis; Tyrosine | 2012 |
Rapid and sensitive determination of protein-nitrotyrosine by ELISA: Application to human plasma.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Animals; Blood Proteins; Cattle; Detergents; Enzyme-Linked Immunosorbent Assay; Female; Humans; Limit of Detection; Middle Aged; Obesity; Oxidation-Reduction; Peroxynitrous Acid; Plasma; Polysorbates; Preservation, Biological; Protein Stability; Reference Standards; Sensitivity and Specificity; Serum; Serum Albumin, Bovine; Temperature; Time Factors; Tyrosine; Young Adult | 2012 |
Diminished muscle growth in the obese Zucker rat following overload is associated with hyperphosphorylation of AMPK and dsRNA-dependent protein kinase.
Topics: AMP-Activated Protein Kinases; Animals; eIF-2 Kinase; Extracellular Signal-Regulated MAP Kinases; Insulin Resistance; Male; Muscle, Skeletal; Obesity; Phosphorylation; Rats; Rats, Zucker; Serine; Signal Transduction; Threonine; Tyrosine; Ubiquitination | 2012 |
Testosterone interacts with the feedback mechanisms engaged by Tyr985 of the leptin receptor and diet-induced obesity.
Topics: Animals; Diet, High-Fat; Estradiol; Feedback, Physiological; Female; Hypothalamus; Longitudinal Studies; Male; Mice; Mice, Knockout; Obesity; Orchiectomy; Ovariectomy; Receptors, Androgen; Receptors, Leptin; Testosterone; Tyrosine | 2012 |
Low myocardial protein kinase G activity in heart failure with preserved ejection fraction.
Topics: Aortic Valve Stenosis; Biopsy; Cohort Studies; Comorbidity; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Diabetes Mellitus; Female; Heart; Heart Failure; Humans; Male; Middle Aged; Myocardium; Natriuretic Peptide, Brain; Obesity; Oxidative Stress; Stroke Volume; Tyrosine | 2012 |
Sfrp5 correlates with insulin resistance and oxidative stress.
Topics: Adaptor Proteins, Signal Transducing; Adiponectin; Animals; Body Mass Index; Clinical Trials as Topic; Coffee; Dinoprost; Eye Proteins; Humans; Insulin; Insulin Resistance; Membrane Proteins; Mice; Middle Aged; Models, Animal; Obesity; Oxidative Stress; Proto-Oncogene Proteins; Statistics as Topic; Tyrosine; Wnt Proteins; Wnt Signaling Pathway; Wnt-5a Protein | 2013 |
Enhanced cAMP generation and insulin-releasing potency of two novel Tyr1-modified enzyme-resistant forms of glucose-dependent insulinotropic polypeptide is associated with significant antihyperglycaemic activity in spontaneous obesity-diabetes.
Topics: Animals; Blood Glucose; Cells, Cultured; Cricetinae; Cyclic AMP; Diabetes Complications; Diabetes Mellitus; Dipeptidyl Peptidase 4; Gastric Inhibitory Polypeptide; Hypoglycemia; Insulin; Insulin Secretion; Mice; Obesity; Protein Isoforms; Spectrometry, Mass, Electrospray Ionization; Tyrosine | 2002 |
Oxidant stress-induced increase in myogenic activation of skeletal muscle resistance arteries in obese Zucker rats.
Topics: Animals; Arteries; Blood Pressure; Catalase; Endothelium, Vascular; Fatty Acids, Unsaturated; In Vitro Techniques; Male; Muscle, Skeletal; Obesity; Oxidative Stress; Peroxynitrous Acid; Polyethylene Glycols; Potassium Channel Blockers; Potassium Channels, Calcium-Activated; Rats; Rats, Zucker; Superoxide Dismutase; Tyrosine; Vascular Patency; Vascular Resistance; Vasoconstriction; Vasomotor System | 2002 |
Reduction of protein tyrosine phosphatase 1B increases insulin-dependent signaling in ob/ob mice.
Topics: Animals; Blood Glucose; Diabetes Mellitus; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Insulin; Insulin Receptor Substrate Proteins; Liver; Mice; Mice, Inbred C57BL; Muscle, Skeletal; Obesity; Oligonucleotides, Antisense; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Protein Serine-Threonine Kinases; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Receptor, Insulin; Serine; Signal Transduction; Tyrosine | 2003 |
Dietary cod protein restores insulin-induced activation of phosphatidylinositol 3-kinase/Akt and GLUT4 translocation to the T-tubules in skeletal muscle of high-fat-fed obese rats.
Topics: Animals; Biological Transport; Dietary Fats; Dietary Proteins; Enzyme Activation; Fish Products; Glucose Transporter Type 4; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Insulin; Male; Monosaccharide Transport Proteins; Muscle Proteins; Muscle, Skeletal; Obesity; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Kinase C; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Tyrosine | 2003 |
Insulin-stimulated protein kinase C lambda/zeta activity is reduced in skeletal muscle of humans with obesity and type 2 diabetes: reversal with weight reduction.
Topics: 3-Phosphoinositide-Dependent Protein Kinases; Adult; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diet; Energy Intake; Female; Humans; Insulin Receptor Substrate Proteins; Isoenzymes; Male; Middle Aged; Muscle, Skeletal; Obesity; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase C-epsilon; Protein Kinase C-theta; Protein Serine-Threonine Kinases; Receptor, Insulin; Tyrosine; Weight Loss | 2003 |
Nutrient intakes and physical growth of children with phenylketonuria undergoing nutrition therapy.
Topics: Body Height; Body Weight; Child; Child Nutritional Physiological Phenomena; Child, Preschool; Dietary Proteins; Eating; Energy Intake; Female; Food, Formulated; Growth; Humans; Longitudinal Studies; Male; Nutrition Policy; Nutritional Requirements; Obesity; Phenylalanine; Phenylketonurias; Tyrosine; United States | 2003 |
[CLINICAL STUDIES ON THE INTERMEDIARY METABOLISM OF TYROSINE. 3. URINARY EXCRETION ON INTERMEDIARY METABOLITES OF TYROSINE IN PATIENTS WITH SOME ENDOCRINE DISEASES AND THE RELATED DISORDERS].
Topics: Addison Disease; Biomedical Research; Diabetes Mellitus; Endocrine System Diseases; Humans; Hypercholesterolemia; Hypoparathyroidism; Lactates; Obesity; Phenylpyruvic Acids; Proteins; Scleroderma, Systemic; Thyroid Diseases; Tyrosine; Urine | 1964 |
Prevention and reversal of premature endothelial cell senescence and vasculopathy in obesity-induced diabetes by ebselen.
Topics: Acetylcholine; Animals; Antioxidants; Aorta, Thoracic; Azoles; Cell Cycle Proteins; Cellular Senescence; Diabetes Mellitus; Endothelial Cells; Endothelium, Vascular; In Vitro Techniques; Isoindoles; Microcirculation; Muscle, Skeletal; Neovascularization, Physiologic; Nitric Oxide; Obesity; Organoselenium Compounds; Rats; Rats, Zucker; Tyrosine; Vasodilation; Vasodilator Agents | 2004 |
Binge ethanol exposure increases liver injury in obese rats.
Topics: Adenosine Triphosphate; Animals; Apoptosis; Body Weight; Cytochrome P-450 CYP2E1; Ethanol; Fatty Acids, Nonesterified; Glutathione; Ion Channels; Lipid Peroxidation; Liver; Male; Membrane Transport Proteins; Mitochondrial Proteins; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Obesity; Organ Size; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Zucker; Tyrosine; Uncoupling Protein 2 | 2003 |
[Study on the association of PPP1R3 gene polymorphism with type 2 diabetes in Han population of Anhui province].
Topics: Adult; Alleles; Aspartic Acid; China; Diabetes Mellitus, Type 2; Female; Gene Frequency; Genotype; Humans; Male; Middle Aged; Obesity; Phosphoprotein Phosphatases; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Protein Phosphatase 1; Risk Factors; Tyrosine | 2004 |
Allosteric inhibition of protein tyrosine phosphatase 1B.
Topics: Allosteric Site; Animals; Binding Sites; Binding, Competitive; Catalysis; Catalytic Domain; CHO Cells; Cloning, Molecular; Cricetinae; Crystallography, X-Ray; DNA; Dose-Response Relationship, Drug; Humans; Inhibitory Concentration 50; Kinetics; Ligands; Models, Chemical; Models, Molecular; Obesity; Phosphoric Monoester Hydrolases; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatases; Time Factors; Transfection; Tyrosine | 2004 |
Serum adiponectin as a biomarker for in vivo PPARgamma activation and PPARgamma agonist-induced efficacy on insulin sensitization/lipid lowering in rats.
Topics: Adiponectin; Animals; Biomarkers; Carrier Proteins; Diabetes Mellitus; Fatty Acid-Binding Proteins; Insulin; Insulin Resistance; Intercellular Signaling Peptides and Proteins; Lipids; Male; Obesity; Oxazoles; Pioglitazone; PPAR gamma; Rats; Rats, Sprague-Dawley; Rats, Zucker; Thiazolidinediones; Tyrosine | 2004 |
A de novo mutation affecting human TrkB associated with severe obesity and developmental delay.
Topics: Age Factors; Animals; Blotting, Western; Body Mass Index; Body Weight; Brain-Derived Neurotrophic Factor; Child; COS Cells; Cysteine; Developmental Disabilities; DNA Mutational Analysis; Eating; Fluorescent Antibody Technique; Gene Expression Regulation; Humans; Male; MAP Kinase Signaling System; Memory Disorders; Mutation, Missense; Obesity; PC12 Cells; Phosphorylation; Rats; Receptor, trkB; Transfection; Tyrosine | 2004 |
Short-term in vivo inhibition of insulin receptor substrate-1 expression leads to insulin resistance, hyperinsulinemia, and increased adiposity.
Topics: Adipose Tissue; Animals; Body Weight; Epididymis; Glucose; Glucose Clamp Technique; Glucose Tolerance Test; Glucose Transporter Type 4; Immunoblotting; Immunoprecipitation; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Liver; Male; Monosaccharide Transport Proteins; Muscle Proteins; Muscle, Skeletal; Obesity; Phosphoproteins; Phosphorylation; Rats; Rats, Wistar; Serine; Signal Transduction; Subcellular Fractions; Time Factors; Tissue Distribution; Tyrosine | 2005 |
Impaired arachidonic acid-mediated dilation of small mesenteric arteries in Zucker diabetic fatty rats.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Animals; Arachidonate 12-Lipoxygenase; Arachidonic Acid; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Eicosanoids; Male; Mesenteric Arteries; Nitrogen; Obesity; Potassium Channels; Rats; Rats, Zucker; RNA, Messenger; Tyrosine; Vasodilation | 2005 |
Reduction of adiposity with prolonged growth hormone treatment in old obese rats: effects on glucose handling and early insulin signaling.
Topics: Adipose Tissue; Aging; Animals; Area Under Curve; Enzyme-Linked Immunosorbent Assay; Female; Glucose; Growth Hormone; Humans; Immunoprecipitation; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Janus Kinase 2; Lipid Metabolism; Liver; Muscles; Obesity; Phosphoproteins; Phosphorylation; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA; Signal Transduction; Time Factors; Tyrosine | 2005 |
Enhanced susceptibility to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity in high-fat diet-induced obesity.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animal Feed; Animals; Antioxidants; Astrocytes; Blotting, Western; Body Weight; Chromatography, High Pressure Liquid; Dietary Fats; Disease Susceptibility; Dopamine; Dopamine Agents; Glial Fibrillary Acidic Protein; Immunoblotting; Immunohistochemistry; Lipid Peroxidation; Male; Mice; Mice, Inbred C57BL; Mice, Obese; MPTP Poisoning; Neurons; Neurotoxicity Syndromes; Nitrates; Nitric Oxide; Nitrites; Obesity; Oxidative Stress; Phosphorylation; Substantia Nigra; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Time Factors; Tyrosine | 2005 |
[Expression of insulin receptor substrate 1 and phosphorylation of tyrosine in adipose tissue of polycystic ovary syndrome].
Topics: Adipose Tissue; Adult; Blotting, Western; Female; Humans; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Obesity; Phosphoproteins; Phosphorylation; Polycystic Ovary Syndrome; Signal Transduction; Tyrosine | 2005 |
Relationships between human serum resistin, inflammatory markers and insulin resistance.
Topics: Biomarkers; Blood Glucose; Body Composition; Body Mass Index; C-Reactive Protein; Case-Control Studies; Homeostasis; Humans; Insulin; Insulin Resistance; Male; Middle Aged; Obesity; Regression Analysis; Resistin; Triglycerides; Tyrosine; Uric Acid | 2005 |
Increased collagen content in insulin-resistant skeletal muscle.
Topics: Adult; Biopsy; Collagen Type I; Collagen Type III; Diabetes Mellitus, Type 2; Extracellular Matrix; Female; Glucose; Humans; Hydroxyproline; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Male; Microscopy, Fluorescence; Middle Aged; Muscle, Skeletal; Obesity; Phosphoproteins; Phosphorylation; Tyrosine | 2006 |
Effect of hereditary obesity on renal expressions of NO synthase, caveolin-1, AKt, guanylate cyclase, and calmodulin.
Topics: Animals; Body Weight; Calmodulin; Caveolin 1; Down-Regulation; Guanylate Cyclase; Immunohistochemistry; Kidney; Male; Nitrates; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; Nitrites; Obesity; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Rats, Zucker; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase; Tyrosine | 2005 |
High-fat diet-induced juvenile obesity leads to cardiomyocyte dysfunction and upregulation of Foxo3a transcription factor independent of lipotoxicity and apoptosis.
Topics: Aconitate Hydratase; Animals; Apoptosis; Calcium; Calcium-Binding Proteins; Calcium-Transporting ATPases; Ceramides; Dietary Fats; Forkhead Box Protein O3; Forkhead Transcription Factors; In Vitro Techniques; Male; Myocytes, Cardiac; Nitric Oxide Synthase; Obesity; Potassium Channels, Voltage-Gated; Rats; Rats, Sprague-Dawley; Sarcoplasmic Reticulum; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Sirtuin 1; Sirtuins; STAT3 Transcription Factor; Triglycerides; Tyrosine; Up-Regulation | 2006 |
Activation of the Cbl insulin signaling pathway in cardiac muscle; dysregulation in obesity and diabetes.
Topics: Adipose Tissue; Animals; Diabetes Mellitus; Diabetes Mellitus, Experimental; Down-Regulation; Insulin; Insulin Resistance; Mice; Mice, Inbred BALB C; Mice, Obese; Muscle, Skeletal; Myocardium; Obesity; Phosphorylation; Proto-Oncogene Proteins c-cbl; rho GTP-Binding Proteins; Signal Transduction; Tyrosine | 2006 |
Subcutaneous fat modulates insulin sensitivity in mice by regulating TNF-alpha expression in visceral fat.
Topics: Animals; Epididymis; Gene Expression; Glucose Tolerance Test; Insulin Receptor Substrate Proteins; Insulin Resistance; Intra-Abdominal Fat; Lipectomy; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Muscle, Skeletal; Obesity; Phosphoproteins; Phosphorylation; Subcutaneous Fat; Tumor Necrosis Factor-alpha; Tyrosine | 2006 |
Short-term lifestyle modification alters circulating biomarkers of endothelial health in sedentary, overweight adults.
Topics: Adolescent; Adult; Biomarkers; Body Mass Index; Cell Adhesion; Endothelium, Vascular; Energy Intake; Exercise; Fasting; Female; Humans; Intercellular Adhesion Molecule-1; Life Style; Male; Obesity; Phospholipases A; Phospholipases A2; Tyrosine | 2006 |
Mice lacking inhibitory leptin receptor signals are lean with normal endocrine function.
Topics: Amino Acid Substitution; Animals; Endocrine System; Female; Leptin; Male; Mice; Mice, Inbred C57BL; Obesity; Receptors, Cell Surface; Receptors, Leptin; Sensitivity and Specificity; Sex Factors; Signal Transduction; Thinness; Tyrosine | 2007 |
Induction of cytochrome P450 2E1 [corrected] promotes liver injury in ob/ob mice.
Topics: Acetone; Animals; Apoptosis; Caspase 3; Catalysis; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP2E1; DNA Adducts; DNA Fragmentation; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Lipid Peroxidation; Liver; Liver Diseases; Male; Mice; Mice, Inbred C57BL; Mice, Obese; Nitric Oxide Synthase Type II; Obesity; Proteins; Pyrazoles; RNA, Messenger; Solvents; Tumor Necrosis Factor-alpha; Tyrosine | 2007 |
Pioglitazone ameliorates endothelial dysfunction in obese rats with nephropathy.
Topics: Animals; Endothelium, Vascular; Kidney Diseases; Kidney Glomerulus; Male; Metabolic Syndrome; NADPH Oxidases; Obesity; Pioglitazone; Polymerase Chain Reaction; Rats; Rats, Zucker; RNA, Messenger; Thiazolidinediones; Tyrosine; Vasodilation | 2007 |
Attenuation of vascular/neural dysfunction in Zucker rats treated with enalapril or rosuvastatin.
Topics: Acetylcholine; Angiotensin-Converting Enzyme Inhibitors; Animals; Arterioles; Cardiovascular System; Disease Models, Animal; Enalapril; Fluorobenzenes; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Metabolic Syndrome; Motor Neurons; Neural Conduction; Neurons, Afferent; Nociceptors; Obesity; Peripheral Nerves; Pyrimidines; Rats; Rats, Zucker; Rosuvastatin Calcium; Sciatic Nerve; Sulfonamides; Superoxides; Tyrosine; Vasodilator Agents | 2008 |
PTP1B regulates cortactin tyrosine phosphorylation by targeting Tyr446.
Topics: Actins; Animals; Apoptosis; Cell Adhesion; Cell Movement; Chlorocebus aethiops; Cortactin; COS Cells; Cytoskeleton; Diabetes Mellitus; HeLa Cells; Humans; Obesity; Phosphorylation; Protein Binding; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Signal Transduction; Tyrosine | 2008 |
Gamma-synuclein is an adipocyte-neuron gene coordinately expressed with leptin and increased in human obesity.
Topics: 3T3-L1 Cells; Adipocytes; Adipose Tissue; Animals; Benzophenones; Blotting, Western; Cell Differentiation; Female; gamma-Synuclein; Gene Expression; Humans; Immunohistochemistry; Indians, North American; Leptin; Mice; Obesity; Peripheral Nervous System; Polymerase Chain Reaction; PPAR gamma; Rats; RNA, Messenger; Tyrosine | 2008 |
Regulation of hepatic tyrosine aminotransferase in genetically obese rats.
Topics: Adrenalectomy; Aging; Amino Acids; Animals; Corticosterone; Diet; Disease Models, Animal; Enzyme Activation; Insulin; Liver; Obesity; Rats; Tryptophan; Tyrosine; Tyrosine Transaminase | 1983 |
[Effect of insulin on amino acid transport and protein synthesis in the skeletal muscle of the normal mouse and the insulin-resistant mouse].
Topics: Amino Acids; Aminoisobutyric Acids; Animals; Biological Transport; Insulin; Insulin Resistance; Mice; Mice, Inbred C57BL; Muscle Proteins; Muscles; Obesity; Tyrosine | 1983 |
Amino acids and obesity.
Topics: Amino Acids; Amino Acids, Branched-Chain; Appetite Depressants; Arginine; Aspartame; Cysteine; Humans; Obesity; Tryptophan; Tyrosine | 1984 |
Obesity and precursor availability affect urinary catecholamine metabolite production in women.
Topics: Adult; Amino Acids; Body Composition; Catecholamines; Circadian Rhythm; Dietary Proteins; Dopamine; Energy Intake; Female; Homovanillic Acid; Humans; Methoxyhydroxyphenylglycol; Norepinephrine; Obesity; Tyrosine; Vanilmandelic Acid | 1983 |
Reduced tyrosine kinase activity of the insulin receptor in obesity-diabetes. Central role of tumor necrosis factor-alpha.
Topics: Adipose Tissue; Animals; Diabetes Mellitus; Diabetes Mellitus, Type 2; Disease Models, Animal; Immunoglobulin G; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Liver; Male; Muscles; Neutralization Tests; Obesity; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Rats; Rats, Zucker; Receptor, Insulin; Receptors, Tumor Necrosis Factor; Recombinant Fusion Proteins; Specific Pathogen-Free Organisms; Tumor Necrosis Factor-alpha; Tyrosine | 1994 |
Insulin receptor phosphorylation, insulin receptor substrate-1 phosphorylation, and phosphatidylinositol 3-kinase activity are decreased in intact skeletal muscle strips from obese subjects.
Topics: Adult; Biological Transport; Biopsy; Glucose; Humans; In Vitro Techniques; Insulin; Insulin Receptor Substrate Proteins; Muscle, Skeletal; Obesity; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Phosphotyrosine; Receptor, Insulin; Reference Values; Tyrosine | 1995 |
Phosphotyrosine-containing proteins in the CNS of obese Zucker rats are decreased in the absence of changes in the insulin receptor.
Topics: Amino Acid Sequence; Animals; Blotting, Western; Hippocampus; Immunohistochemistry; Insulin; Male; Molecular Sequence Data; Nerve Tissue Proteins; Obesity; Phosphoproteins; Phosphorylation; Phosphotyrosine; Prosencephalon; Protein-Tyrosine Kinases; Rats; Rats, Zucker; Receptor, Insulin; Tyrosine | 1993 |
Early alteration of insulin stimulation of PI 3-kinase in muscle and adipocyte from gold thioglucose obese mice.
Topics: Adipocytes; Adipose Tissue; Animals; Aurothioglucose; Biological Transport; Epididymis; Glucose; Insulin; Male; Mice; Mice, Inbred Strains; Muscle Proteins; Muscle, Skeletal; Muscles; Obesity; Phosphatidylinositol 3-Kinases; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Receptor Protein-Tyrosine Kinases; Tyrosine | 1995 |
Long-term effect of dexfenfluramine on amino acid profiles and food selection in obese patients during weight loss.
Topics: Adult; Amino Acids; Appetite Depressants; Dietary Fats; Dietary Proteins; Female; Fenfluramine; Food Preferences; Humans; Male; Obesity; Tryptophan; Tyrosine; Weight Loss | 1996 |
Leptin induces tyrosine phosphorylation of cellular proteins including STAT-1 in human renal adenocarcinoma cells, ACHN.
Topics: Adenocarcinoma; Blotting, Western; DNA-Binding Proteins; Humans; Kidney Neoplasms; Leptin; Obesity; Phosphorylation; Proteins; Recombinant Proteins; STAT1 Transcription Factor; Trans-Activators; Tumor Cells, Cultured; Tyrosine | 1996 |
Phenotype of the obese Koletsky (f) rat due to Tyr763Stop mutation in the extracellular domain of the leptin receptor (Lepr): evidence for deficient plasma-to-CSF transport of leptin in both the Zucker and Koletsky obese rat.
Topics: Animals; Brain; Carrier Proteins; DNA Primers; Genotype; Leptin; Mutation; Obesity; Phenotype; Point Mutation; Polymerase Chain Reaction; Proteins; Rats; Rats, Mutant Strains; Rats, Zucker; Receptors, Cell Surface; Receptors, Leptin; Tyrosine | 1997 |
Divergent signaling capacities of the long and short isoforms of the leptin receptor.
Topics: Animals; Carrier Proteins; CHO Cells; Cloning, Molecular; COS Cells; Cricetinae; DNA-Binding Proteins; DNA, Complementary; Humans; Insulin Receptor Substrate Proteins; Mice; Obesity; Phosphoproteins; Phosphorylation; Proto-Oncogene Proteins c-fos; Receptors, Cell Surface; Receptors, Leptin; Signal Transduction; STAT3 Transcription Factor; Trans-Activators; Transcription, Genetic; Tyrosine | 1997 |
Leptin induces proliferation of pancreatic beta cell line MIN6 through activation of mitogen-activated protein kinase.
Topics: Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Division; Cell Line; Cell Survival; DNA; Enzyme Activation; Flavonoids; Islets of Langerhans; Leptin; Mice; Obesity; Phosphorylation; Proteins; Signal Transduction; Trans-Activators; Tyrosine | 1997 |
[Molecular endocrinology of hereditary obesity].
Topics: Adipose Tissue; Chorionic Gonadotropin; Gene Expression Regulation, Enzymologic; Gluconeogenesis; Glucose Intolerance; Humans; Hypogonadism; Hypothalamic Diseases; Hypothalamo-Hypophyseal System; Obesity; Pituitary-Adrenal System; Prostaglandins; Tyrosine | 1997 |
Functional properties of leptin receptor isoforms containing the gln-->pro extracellular domain mutation of the fatty rat.
Topics: Amino Acid Sequence; Animals; Binding, Competitive; Carrier Proteins; CHO Cells; Cricetinae; DNA-Binding Proteins; Early Growth Response Protein 1; Humans; Immediate-Early Proteins; Isomerism; Janus Kinase 2; Leptin; Mice; Mutation; Obesity; Oxidation-Reduction; Phosphorylation; Promoter Regions, Genetic; Protein-Tyrosine Kinases; Proteins; Proto-Oncogene Proteins; Rats; Rats, Zucker; Receptors, Cell Surface; Receptors, Leptin; Recombinant Proteins; STAT3 Transcription Factor; Trans-Activators; Transcription Factors; Tyrosine | 1998 |
An in vivo model for elucidation of the mechanism of tumor necrosis factor-alpha (TNF-alpha)-induced insulin resistance: evidence for differential regulation of insulin signaling by TNF-alpha.
Topics: Animals; Blood Physiological Phenomena; Glucose Clamp Technique; Humans; Insulin; Insulin Resistance; Liver; Mice; Obesity; Phosphorylation; Protein Tyrosine Phosphatases; Rats; Rats, Zucker; Receptor, Insulin; Reference Values; Signal Transduction; Tumor Necrosis Factor-alpha; Tyrosine | 1998 |
Mechanisms of antihyperglycemic effects of moxonidine in the obese spontaneously hypertensive Koletsky rat (SHROB).
Topics: Animals; Antihypertensive Agents; Female; Glucose Tolerance Test; Glucose Transporter Type 4; Hypertension; Hypoglycemic Agents; Imidazoles; Insulin; Insulin Receptor Substrate Proteins; Liver; Male; Monosaccharide Transport Proteins; Muscle Proteins; Muscle, Skeletal; Obesity; Phosphoproteins; Phosphorylation; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Receptor, Insulin; Tyrosine | 1999 |
A novel N-aryl tyrosine activator of peroxisome proliferator-activated receptor-gamma reverses the diabetic phenotype of the Zucker diabetic fatty rat.
Topics: Animals; Benzophenones; Chromans; Clone Cells; Diabetes Mellitus, Experimental; Glucose Clamp Technique; Humans; Hypoglycemic Agents; Immunohistochemistry; Logistic Models; Obesity; Phenotype; Rats; Rats, Zucker; Receptors, Cytoplasmic and Nuclear; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone; Tyrosine | 1999 |
Dephosphorylation increases insulin-stimulated receptor kinase activity in skeletal muscle of obese Zucker rats.
Topics: Animals; Enzyme Activation; Glucose; Insulin; Insulin Receptor Substrate Proteins; Male; Muscle, Skeletal; Obesity; Phosphoproteins; Phosphorylation; Rats; Rats, Zucker; Receptor Protein-Tyrosine Kinases; Receptor, Insulin; Tyrosine | 1999 |
Characterization of selective resistance to insulin signaling in the vasculature of obese Zucker (fa/fa) rats.
Topics: Animals; Aorta; Calcium-Calmodulin-Dependent Protein Kinases; In Vitro Techniques; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Intracellular Signaling Peptides and Proteins; Liver; Male; Microcirculation; Obesity; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Rats; Rats, Zucker; Receptor, Insulin; Recombinant Proteins; Signal Transduction; Tyrosine | 1999 |
Metabolic differences between genetically lean and fat chickens are partly attributed to the alteration of insulin signaling in liver.
Topics: Animals; Blood Glucose; Chickens; Eating; Genes, src; Insulin; Liver; Muscles; Nutritional Status; Obesity; Phosphorylation; Receptor, Insulin; Signal Transduction; Starvation; Tyrosine | 1999 |
Sex differences in the effect of obesity on human plasma tryptophan/large neutral amino acid ratio.
Topics: Amino Acids; Body Mass Index; Female; Humans; Leucine; Male; Obesity; Phenylalanine; Sex Characteristics; Tryptophan; Tyrosine; Valine | 1999 |
Insulin resistance in fat cells from obese Zucker rats--evidence for an impaired activation and translocation of protein kinase B and glucose transporter 4.
Topics: Adipocytes; Aging; Animals; Electrophoresis, Polyacrylamide Gel; Glucose; Glucose Transporter Type 4; Immunoblotting; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Intracellular Signaling Peptides and Proteins; Monosaccharide Transport Proteins; Muscle Proteins; Obesity; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Precipitin Tests; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Zucker; Signal Transduction; Tyrosine; Vanadates | 2000 |
Tumor necrosis factor-alpha induces hepatic insulin resistance in obese Zucker (fa/fa) rats via interaction of leukocyte antigen-related tyrosine phosphatase with focal adhesion kinase.
Topics: Animals; CSK Tyrosine-Protein Kinase; Down-Regulation; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Insulin; Insulin Resistance; Liver; Obesity; Phosphorylation; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Rats; Rats, Zucker; Receptor-Like Protein Tyrosine Phosphatases, Class 4; Receptor, Insulin; Receptors, Cell Surface; Recombinant Proteins; src-Family Kinases; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Tyrosine | 2000 |
Divergent regulation of Akt1 and Akt2 isoforms in insulin target tissues of obese Zucker rats.
Topics: Adipose Tissue; Animals; Biological Transport; Female; Glucose; Insulin; Insulin Receptor Substrate Proteins; Isoenzymes; Obesity; Peptide Fragments; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Rats, Zucker; Reference Values; Tissue Distribution; Tyrosine | 2000 |
Vanadate enhances but does not normalize glucose transport and insulin receptor phosphorylation in skeletal muscle from obese women with gestational diabetes mellitus.
Topics: Biological Transport; Diabetes, Gestational; Female; Glucose; Humans; Insulin Receptor Substrate Proteins; Muscle, Skeletal; Obesity; Phosphoproteins; Phosphorylation; Pregnancy; Pregnancy Complications; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatases; Receptor, Insulin; Reference Values; Tyrosine; Vanadates | 2000 |
Characterization of pathogenic and prognostic factors of nonalcoholic steatohepatitis associated with obesity.
Topics: Adult; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Endoglin; Female; Hepatitis; Humans; Immunohistochemistry; Intercellular Adhesion Molecule-1; Lectins, C-Type; Liver; Liver Cirrhosis; Male; Middle Aged; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Obesity; Prognosis; Receptors, Cell Surface; Tyrosine; Vascular Cell Adhesion Molecule-1 | 2000 |
Effects of tungstate, a new potential oral antidiabetic agent, in Zucker diabetic fatty rats.
Topics: Administration, Oral; Animals; Diabetes Mellitus; Glucose-6-Phosphate; Glycogen; Hyperglycemia; Hypoglycemic Agents; Islets of Langerhans; Liver; Male; Obesity; Phosphorylation; Rats; Rats, Zucker; Tungsten Compounds; Tyrosine | 2001 |
Comprehensive messenger ribonucleic acid profiling reveals that peroxisome proliferator-activated receptor gamma activation has coordinate effects on gene expression in multiple insulin-sensitive tissues.
Topics: Adipose Tissue; Adipose Tissue, Brown; Animals; Benzophenones; Diabetes Mellitus; Fatty Acids; Gene Expression; Gene Expression Profiling; Glucose; Homeostasis; Insulin; Liver; Muscle, Skeletal; Obesity; Rats; Rats, Zucker; Receptors, Cytoplasmic and Nuclear; Transcription Factors; Tyrosine | 2001 |
The suppressive effect of dietary restriction and weight loss in the obese on the generation of reactive oxygen species by leukocytes, lipid peroxidation, and protein carbonylation.
Topics: Adult; Aged; Diet, Reducing; Female; Glucose Tolerance Test; Humans; Leukocytes; Linoleic Acid; Linoleic Acids; Linoleic Acids, Conjugated; Lipid Peroxides; Male; Middle Aged; Obesity; Phenylalanine; Proteins; Reactive Oxygen Species; Thiobarbituric Acid Reactive Substances; Tyrosine; Weight Loss | 2001 |
Adipose tissue resistin expression is severely suppressed in obesity and stimulated by peroxisome proliferator-activated receptor gamma agonists.
Topics: Adipocytes; Animals; Benzophenones; Down-Regulation; Hormones, Ectopic; Hypoglycemic Agents; Intercellular Signaling Peptides and Proteins; Male; Mice; Nerve Growth Factor; Obesity; Proteins; Rats; Receptors, Cytoplasmic and Nuclear; Resistin; Rosiglitazone; Thiazoles; Thiazolidinediones; Transcription Factors; Tyrosine | 2001 |
SOCS-3 inhibits insulin signaling and is up-regulated in response to tumor necrosis factor-alpha in the adipose tissue of obese mice.
Topics: 3T3 Cells; Adipose Tissue; Animals; COS Cells; Insulin; Insulin Receptor Substrate Proteins; Male; Mice; Mice, Transgenic; Obesity; Phosphoproteins; Phosphorylation; Proteins; Repressor Proteins; RNA, Messenger; Signal Transduction; Suppressor of Cytokine Signaling 3 Protein; Suppressor of Cytokine Signaling Proteins; Transcription Factors; Tumor Necrosis Factor-alpha; Tyrosine; Up-Regulation | 2001 |
Study on action of acupuncture on ventromedial nucleus of hypothalamus in obese rats.
Topics: Acupuncture; Animals; Dopamine; Hypothalamus; Male; Obesity; Random Allocation; Rats; Rats, Sprague-Dawley; Serotonin; Tyrosine; Ventromedial Hypothalamic Nucleus | 2001 |
Uptake and metabolism of iodine is crucial for the development of thyroiditis in obese strain chickens.
Topics: Amitrole; Animals; Chickens; Immunotherapy, Adoptive; Iodine; Obesity; Perchlorates; Potassium; Potassium Compounds; Propylthiouracil; Thyroid Gland; Thyroiditis, Autoimmune; Thyrotropin; Tyrosine | 1991 |
Mechanism of defective insulin-receptor kinase activity in NIDDM. Evidence for two receptor populations.
Topics: Adipose Tissue; Adult; Aged; Diabetes Mellitus; Diabetes Mellitus, Type 2; Humans; Insulin; Middle Aged; Obesity; Phosphorylation; Phosphotyrosine; Precipitin Tests; Protein-Tyrosine Kinases; Receptor, Insulin; Tyrosine | 1989 |
Protein turnover in insulin-treated, alloxan-diabetic lean and obese Zucker rats.
Topics: Animals; Body Weight; Diabetes Mellitus, Experimental; Insulin; Kinetics; Liver; Male; Methylhistidines; Muscle Development; Muscle Proteins; Myofibrils; Nitrogen; Obesity; Proteins; Rats; Rats, Zucker; Sarcoplasmic Reticulum; Tyrosine | 1985 |
Effects of oral contraceptives and obesity on carrier tests for phenylketonuria.
Topics: Adult; Contraceptives, Oral; Fasting; Female; Heterozygote; Humans; Menstruation; Middle Aged; Obesity; Ovulation; Phenylalanine; Phenylketonurias; Pregnancy; Temperature; Time Factors; Tyrosine | 1973 |
Daily rhythm of plasma tyrosine in fasting subjects.
Topics: Circadian Rhythm; Fasting; Female; Humans; Male; Obesity; Tyrosine | 1971 |
Plasma amino acid levels and insulin secretion in obesity.
Topics: Adolescent; Adult; Amino Acids; Blood Glucose; Fasting; Feedback; Female; Glucose; Glycine; Humans; Insulin; Insulin Resistance; Insulin Secretion; Isoleucine; Leucine; Male; Middle Aged; Obesity; Pancreas; Phenylalanine; Tyrosine; Valine | 1969 |