Compounds > tyrosine

tyrosine and Neoplasm Metastasis

tyrosine has been researched along with Neoplasm Metastasis in 106 studies

Research

Studies (106)

TimeframeStudies, this research(%)All Research%
pre-199017 (16.04)18.7374
1990's16 (15.09)18.2507
2000's41 (38.68)29.6817
2010's31 (29.25)24.3611
2020's1 (0.94)2.80

Authors

AuthorsStudies
Duarte, A; Isturiz, M; Montagna, DR; Rearte, B; Ruggiero, RA; Todero, MF1
Aute, S; Chattopadhyay, S; Das, A; Guha, R; Mogare, D; Parulekar, A; Ramu, V; Taye, N; Thomas, JA; Walker, MG1
Aprile, C; Buroni, FE; Corbella, F; Facoetti, A; Hodolic, M; Lodola, L; Nano, R; Pasi, F; Persico, MG1
Anselmino, N; Chiarella, P; Contin, MD; Cotignola, J; D Accorso, N; Giudice, J; Gueron, G; Jaworski, F; Labanca, E; Lage Vickers, S; Leonardi, D; Manzano, V; Meiss, RP; Montagna, DR; Navone, N; Ortiz, EG; Paez, AV; Ruggiero, R; Strazza, A; Vazquez, E; Woloszynska-Read, A1
Bode, AM; Cao, Y; Deng, X; Dong, Z; Li, L; Tang, M; Tao, Y; Xiao, L; Xu, J; Yang, L; Zhong, J1
Dreesen, JD; Ergun, S; Giebel, B; Jastrow, H; Muturi, HT; Nilewski, E; Singer, BB1
Cao, X; Fan, L; Huang, F; Jiang, Y; Li, H; Li, J; Pan, H; Sun, J; Wang, Q; Wang, X1
Akbani, R; Armaiz-Pena, GN; Baggerly, KA; Bottsford-Miller, J; Coleman, RL; Dalton, HJ; DeGeest, K; Diao, L; Kang, Y; Lopez-Berestein, G; Lutgendorf, S; Nick, AM; Sanguino, AM; Sood, AK; Stone, RL; Thanapprapasr, D; Zand, B1
Reubi, JC; Waser, B1
Chen, Q; Chen, Z; Gao, WQ; Ji, Z; Wang, J; Wang, L; Zhang, C; Zhang, K; Zhang, P; Zhao, H; Zhou, P; Zhu, HH1
Kos, J; Pečar Fonović, U1
Cárdenas, A; Contreras, P; Cooper-White, J; Díaz, J; Díaz, MI; Díaz, N; Leyton, L; Lobos-Gonzalez, L; Ortiz, R; Otte, E; Quest, AF; Torres, V1
Gnirck, AC; Larsson, O; Lin, Y; Sehat, B; Warsito, D1
Bundschuh, RA; Galldiks, N; Glas, M; Hattingen, E; Herrlinger, U; Kebir, S; Landsberg, J; Langen, KJ; Rauschenbach, L; Scheffler, B; Schlaak, M1
Cai, Y; Chen, A; Han, A; Huang, H; Huang, L; Ji, Z; Jiang, B; Jin, M; Li, Q; Li, X; Lin, F; Ma, H; Suleman, M; Sun, X; Tian, F; Wang, S; Wu, Y; Xie, C; Zhang, J; Zhang, N; Zhao, Q; Zhao, W; Zhou, H; Zhou, L; Zhou, Y1
Ji, W; Niu, R; Sun, X; Tian, R; Wang, Z; Zhang, F; Zhang, J1
Cao, L; Freeman, JW; Jin, C; Lazor, JW; Sperry, J; Venkatasubbarao, K; Zhao, S1
Chung, LW; Gera, L; Iqbal, S; Johnson, NA; Qian, WP; Seo, SI; Stewart, J; Wang, R; Wu, D; Zayzafoon, M; Zhang, S; Zhau, HE1
Bagnato, A; Biroccio, A; Cianfrocca, R; Di Castro, V; Masi, S; Natali, PG; Nicotra, MR; Rosanò, L; Salvati, E; Spinella, F1
Chang, CF; Koay, ES; Wong, LL; Zhang, D1
Aldape, K; Cobb, MH; Gao, X; Halle, M; Hawke, D; He, J; Lu, Z; Tremblay, ML; Xia, Y; Xie, K; Zheng, Y; Zhou, XZ1
Kang, X; Li, H; Li, X; Liu, Y; Ren, Z; Shen, Y; Wang, Y; Xue, T; Zhang, L1
Baek, YH; Choi, DY; Huh, JE; Lee, JD; Lee, MH; Park, DS1
Chang, HY; Chen, LC; Chuang, IC; Liao, PC; Tsay, YG; Tseng, VS; Wu, HY1
Balzer, EM; Cho, EH; Ioffe, OB; Martin, SS; Matrone, MA; Tuttle, KC; Vitolo, MI; Whipple, RA; Yang, J; Yoon, JR1
Bajaj, E; Besmer, D; Gendler, SJ; Hwang, SI; Lee, YY; Mukherjee, P; Nath, S; Roy, LD; Sahraei, M; Shanmugam, K; Subramani, DB; Tinder, TL1
Anders, RA; Edil, BH; Foley, K; Huang, L; Illei, PB; Jaffee, EM; Laheru, D; Le, DT; Leubner, A; Maitra, A; Mizuma, M; Mo, G; Olino, K; Sharma, R; Van Eyk, JE; Zheng, L1
Backer, JM; Boimel, PJ; Bresnick, AR; Condeelis, JS; Coniglio, SJ; Flinn, RJ; Hynes, NE; Pozzuto, M; Segall, JE; Smirnova, T; Wyckoff, J; Zhou, ZN1
Aasheim, HC; Iversen, N; Sandset, PM; Skretting, G; Sletten, M; Stavik, B; Tinholt, M; Zernichow, L1
Dusseault, J; Ismaïl, S; Labelle-Côté, M; Larose, L; Picard-Cloutier, A; Siegel, PM1
Adams, G; Aikhionbare, F; Cao, X; Chen, Y; Ding, X; Fan, L; Frost, A; Hu, G; Liu, D; Liu, H; Partridge, E; Wang, F; Yao, X; Yu, X1
Deng, YZ; Feng, YX; Gao, H; Ji, XD; Li, G; Li, JJ; Shi, S; Sun, ZJ; Wang, T; Xie, D; Xu, JF; Zhao, JS; Zhu, YQ1
Bruzzo, J; Bustuoabad, OD; Chiarella, P; Meiss, RP; Pasqualini, CD; Ruggiero, RA1
Arpin, M; Day, A; Elliott, BE; Mak, H; Naba, A; Schick, C; SenGupta, SK; Varma, S1
Li, X; Ren, H; Sun, X; Zhang, Y; Zhao, Y1
Bruzzo, J; Chiarella, P; Meiss, RP; Ruggiero, RA1
Karanki, SS; Kumar, N; Mishra, J1
Allen, JK; Armaiz-Pena, GN; Bar-Eli, M; Cole, SW; Cruz, A; De Geest, K; Deavers, MT; English, RD; Gallick, GE; Gharpure, KM; Han, LY; Jackson, DB; Lin, YG; Lopez, GE; Lopez-Berestein, G; Lutgendorf, SK; Mangala, LS; Nagaraja, AS; Nick, AM; Rodriguez-Aguayo, C; Shahzad, MM; Shazhad, MM; Soldatos, TG; Soman, KV; Sood, AK; Stone, RL; Torres-Lugo, M; Villares, GJ; Vivas-Mejia, P; Wiktorowicz, JE; Wu, Z; Young, T; Zien, A; Zigler, M1
Akedo, H; Iwasaki, T; Mukai, M; Nakamura, H; Tatsuta, M; Terada, N; Tsujimura, T1
Wei, L; Yang, Y; Yu, Q; Zhang, X1
Fu, X; Fu, YM; Ge, X; Li, YQ; Meadows, GG; Sanchez, PJ; Yu, ZX1
Gutkind, JS; Hitsuda, Y; Igishi, T; Matsumoto, S; Mikami, M; Murakami, K; Nakanishi, H; Shigeoka, Y; Shimizu, E; Yasuda, K1
HALES, IB; MYHILL, J; REEVE, TS; RICHARDS, M; STANLEY, PG1
HERZBERG, JJ1
Bousquet, B; Garnier, JP; Ghanem, G; Le Bricon, T; Letellier, S; Morel, P; Stoitchkov, K; Tsankov, N1
Band, H; Fernandis, AZ; Ganju, RK; Klösel, R; Prasad, A1
Ashley, SW; Duxbury, MS; Ito, H; Whang, EE; Zinner, MJ1
Cheong, C; Cho, JM; Jee, J; Jeon, YH; Kim, KA; Lee, C; Lee, TG; Lee, W; Ro, S; Sheen, MR; Song, JS; Yamazaki, T1
Egorin, MJ; Ilaria, RL; Minna, JD; Randle, DE; Wolff, NC1
Altomonte, M; Calabro, L; Fonsatti, E; Leonardi, A; Maio, M; Pucillo, C; Tecce, R; Visintin, A1
Druker, BJ; Epstein, RJ; Lim, YP; Ooi, LL; Wong, CY1
Alaimo, G; Alessandro, R; Corrado, C; De Leo, A; De Leo, G; Flugy, AM; Russo, D; Stassi, G1
Bamberger, AM; Brümmer, J; Ebrahimnejad, A; Horst, AK; Nollau, P; Streichert, T; Wagener, C1
Chang, NS; Hsu, LJ; Lewis, J; Schultz, L; Su, M; Sze, CI1
Enns, A; Fisch, KM; Gassmann, P; Haier, J; Nicolson, GL; von Sengbusch, A1
Cornillon, J; Denoyer, D; Dubois, F; Le Jeune, N; Perek, N1
Hosokawa, M; Kobayashi, M; Kobayashi, T; Okada, F; Tazawa, H1
Caldelari, R; Getsios, S; Godsel, LM; Green, KJ; Kowalczyk, AP; Müller, EJ; Yin, T1
Cristiani, C; Isacchi, A; Kalisz, HM; Knapp, S; Perego, R; Rusconi, L; Schiering, N1
Corless, CL; Heinrich, MC; Keegan, D; Maguire, D; O'Riain, C; Sheahan, K; Vioreanu, M1
Chen, CT; Lou, PJ; Wang, CP; Yang, TH1
Strous, GJ; van den Eijnden, MJ1
Galliher-Beckley, AJ; Schiemann, WP1
Basson, MD; Craig, DH; Downey, C1
Bagshaw, CR; Barsukov, IL; Basran, J; Gingras, AR; Kriajevska, M; Prescott, A1
Ali, FM; Barnes, DA; Black, ML; Camp, VM; Faraj, BA; Lawson, DH; Nixon, DW; Richmond, A; Tindall, GT1
Aslakson, CJ; Elstad, CA; Meadows, GG; Starkey, JR1
Franssen, EJ; Go, KG; Heesters, MA; Molenaar, WM; Paans, AM; Pruim, J; Vaalburg, W; van Waarde, A; Visser, GM; Willemsen, AT1
Engleka, KA; Forough, R; Friedman, S; Maciag, T; MacPhee, M; Sayers, T; Wiltrout, RH; Xi, Z1
Huijzer, JC; McFarland, M; Meadows, GG; Niles, RM1
Cardeiro, DJ; Elstad, CA; Huijzer, JC; Meadows, GG; Uhlenkott, CE1
Akedo, H; Imamura, F; Isoai, A; Kitagawa, I; Kobayashi, M; Mukai, M; Shinkai, K1
Akimoto, S; Gotoh, M; Hirohashi, S; Kanai, Y; Machinami, R; Ochiai, A; Shibata, T; Yasui, N1
Comolli, R; La Porta, CA1
Brooks, PC; Cheresh, DA; Klemke, RL; Leng, J; Molander, R; Vuori, K1
Akiyoshi, T; Mafune, K; Mori, M; Sugimachi, K; Tanaka, S; Tanaka, Y; Wands, JR1
Ambesi-Impiombato, FS; Besati, C; Cecchini, G; De Filippi, R; Marchisio, PC; Serini, G; Trusolino, L1
Fiscella, M; Jeffers, M; Koochekpour, S; Sathyanarayana, BK; Vande Woude, GF1
Hioki, K; Kameshita, I; Mohri, T; Suzuki, S; Takatani, S; Tokunaga, R1
Cheresh, D; Collins, LR; Ricketts, WA; Yeh, L1
Ahmed, B; Van Den Oord, JJ1
Benali, N; Buscail, L; Calise, D; Cordelier, P; Esteve, JP; Nagy, A; Pages, P; Pour, PM; Rochaix, P; Schally, AV; Susini, C; Vaysse, N1
Fujita, T; Fukayama, M; Kadowaki, T; Kimura, S; Matsuda, S; Miki, H; Nagai, R; Sugiyama, T; Taketani, Y; Tobe, K; Tsushima, T; Ueki, K; Waki, H; Yamamoto, T; Yamauchi, N; Yamauchi, T; Yazaki, Y1
Buzaid, AC; Ekmekcioglu, S; Ellerhorst, J; Grimm, EA; Munsell, M; Prieto, VG; Smid, CM1
Authier, F; Bergeron, JJ; Brodt, P; Chevet, E; Di Guglielmo, GM; Navab, R1
Brodt, P; Fallavollita, L; Khatib, AM; Samani, AA; Zhang, D1
Fernandez, N; Kazanietz, MG; Rotenberg, SA; Sanz-Navares, E1
Chen, Z; Fadiel, A; Feng, Y; Naftolin, F; Ohtani, K; Rutherford, T1
Dinney, CP; Fan, Z; Hicklin, DJ; Izawa, JI; Karashima, T; Kedar, D; Kim, SJ; Pettaway, C; Shuin, T; Slaton, JW; Sweeney, P1
Campbell, IT; Harvie, MN; Howell, A; Thatcher, N1
Agrup, G; Bengtsson, M; Falck, B; Persson, K; Rorsman, H; Rosengren, AM; Rosengren, E1
Benfield, JR; Makarski, JS; Niles, RM1
Hamaguchi, M; Matsuyoshi, N; Nagafuchi, A; Takeichi, M; Taniguchi, S; Tsukita, S1
Iizuka, Y; Iwashita, S; Nishiya, S; Takatori, T; Takayama, Y; Tsuruo, T; Yamazaki, A; Yamori, T1
Abdallah, RM; Meadows, GG; Starkey, JR1
Haberman, HF; Menon, IA1
Buffe, D; Rimbaut, C2
Edmund, J; Egeberg, J; Jensen, OA2
Blois, MS1
Demopoulos, HB; Hourani, BT1
Deppisch, LM; Gang, H; Goldstein, M; Gumport, SL; Sohn, N1
Drewa, G; Zbytniewski, Z1
Anton, AH; Greer, M; Williams, CM1
Demopoulos, HB1

Reviews

2 review(s) available for tyrosine and Neoplasm Metastasis

ArticleYear
Concomitant tumor resistance: the role of tyrosine isomers in the mechanisms of metastases control.
    Cancer research, 2012, Mar-01, Volume: 72, Issue:5

    Topics: Animals; Extracellular Signal-Regulated MAP Kinases; Humans; Lung Neoplasms; Mice; Neoplasm Metastasis; Neoplasms; S Phase; STAT3 Transcription Factor; Tyrosine

2012
Concomitant tumor resistance.
    Cancer letters, 2012, Nov-28, Volume: 324, Issue:2

    Topics: Animals; Cell Proliferation; Humans; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasms; Tumor Burden; Tyrosine

2012

Other Studies

104 other study(ies) available for tyrosine and Neoplasm Metastasis

ArticleYear
Meta-tyrosine modulates the immune response induced by bacterial endotoxins.
    Immunobiology, 2020, Volume: 225, Issue:1

    Topics: Animals; B7-H1 Antigen; Cancer Vaccines; Cell Line, Tumor; Disease Models, Animal; Female; Gene Expression Regulation, Neoplastic; Humans; Immunologic Factors; Lipopolysaccharides; Mammary Neoplasms, Animal; Mice; Mice, Inbred BALB C; Myeloid-Derived Suppressor Cells; Neoplasm Metastasis; Sepsis; Tyrosine

2020
Photo-induced cytotoxicity and anti-metastatic activity of ruthenium(ii)-polypyridyl complexes functionalized with tyrosine or tryptophan.
    Dalton transactions (Cambridge, England : 2003), 2017, May-23, Volume: 46, Issue:20

    Topics: A549 Cells; Antineoplastic Agents; Apoptosis; Biomarkers, Tumor; Caspase 3; Cell Survival; Circulating Tumor DNA; Coordination Complexes; DNA Damage; Humans; Metalloporphyrins; Neoplasm Metastasis; Photochemotherapy; Photosensitizing Agents; Reactive Oxygen Species; Tryptophan; Tyrosine

2017
Uptake of
    Contrast media & molecular imaging, 2017, Volume: 2017

    Topics: Carbon; Cell Line, Tumor; Choline; Diagnosis, Differential; Glioblastoma; Humans; Ions; Neoplasm Metastasis; Photons; Tyrosine

2017
Game-changing restraint of Ros-damaged phenylalanine, upon tumor metastasis.
    Cell death & disease, 2018, 02-02, Volume: 9, Issue:2

    Topics: Animals; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Drug Resistance, Neoplasm; Humans; Male; Mice, Nude; Neoplasm Metastasis; Phenylalanine; Prostatic Neoplasms; Reactive Oxygen Species; Serum; Signal Transduction; Subcutaneous Tissue; Tyrosine; Xenograft Model Antitumor Assays

2018
Tyrosylprotein sulfotransferase-1 and tyrosine sulfation of chemokine receptor 4 are induced by Epstein-Barr virus encoded latent membrane protein 1 and associated with the metastatic potential of human nasopharyngeal carcinoma.
    PloS one, 2013, Volume: 8, Issue:3

    Topics: Binding Sites; Carcinoma; Cell Line, Tumor; Chemotaxis; Flow Cytometry; Gene Deletion; Genes, Reporter; Herpesvirus 4, Human; Humans; Nasopharyngeal Carcinoma; Nasopharyngeal Neoplasms; Neoplasm Invasiveness; Neoplasm Metastasis; Receptors, CXCR4; RNA, Small Interfering; Sulfotransferases; Tyrosine; Viral Matrix Proteins

2013
Tumor and endothelial cell-derived microvesicles carry distinct CEACAMs and influence T-cell behavior.
    PloS one, 2013, Volume: 8, Issue:9

    Topics: Animals; Antibodies, Monoclonal; Antigens, CD; CD28 Antigens; CD3 Complex; Cell Adhesion Molecules; Cell Line, Tumor; Cell Membrane; Cell Proliferation; CHO Cells; Cricetinae; Cricetulus; Endosomes; Endothelial Cells; Humans; Mice; Microcirculation; Neoplasm Metastasis; Neovascularization, Pathologic; Phosphorylation; T-Lymphocytes; Tyrosine

2013
Phosphatidylethanolamine-binding protein 4 is associated with breast cancer metastasis through Src-mediated Akt tyrosine phosphorylation.
    Oncogene, 2014, Sep-11, Volume: 33, Issue:37

    Topics: Animals; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Female; Gene Expression Regulation, Neoplastic; Humans; Matrix Metalloproteinase 13; Matrix Metalloproteinase 9; MCF-7 Cells; Mice; Mice, Nude; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Transplantation; Phosphatidylethanolamine Binding Protein; Phosphorylation; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; src-Family Kinases; Tissue Array Analysis; Tyrosine

2014
Focal adhesion kinase: an alternative focus for anti-angiogenesis therapy in ovarian cancer.
    Cancer biology & therapy, 2014, Volume: 15, Issue:7

    Topics: Angiogenesis Inhibitors; Animals; Carcinoma, Ovarian Epithelial; Cell Movement; Cell Proliferation; Endothelial Cells; Female; Focal Adhesion Protein-Tyrosine Kinases; Gene Dosage; Humans; Indoles; Mice, Nude; Neoplasm Metastasis; Neoplasms, Glandular and Epithelial; Neovascularization, Pathologic; Ovarian Neoplasms; Phosphorylation; Protein Kinase Inhibitors; Sulfonamides; Tyrosine

2014
Triple-peptide receptor targeting in vitro allows detection of all tested gut and bronchial NETs.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2015, Volume: 56, Issue:4

    Topics: Autoradiography; Bronchial Neoplasms; Glucagon-Like Peptide-1 Receptor; Humans; Insulinoma; Iodine Radioisotopes; Ligands; Neoplasm Metastasis; Neuroendocrine Tumors; Octreotide; Pancreatic Neoplasms; Protein Binding; Receptors, Gastrointestinal Hormone; Receptors, Glucagon; Receptors, Peptide; Receptors, Somatostatin; Tyrosine

2015
Shp2 promotes metastasis of prostate cancer by attenuating the PAR3/PAR6/aPKC polarity protein complex and enhancing epithelial-to-mesenchymal transition.
    Oncogene, 2016, Mar-10, Volume: 35, Issue:10

    Topics: Adaptor Proteins, Signal Transducing; Cell Cycle Proteins; Cell Polarity; Epithelial-Mesenchymal Transition; Humans; Male; Membrane Proteins; Neoplasm Metastasis; Neoplasm Staging; Phosphorylation; Prostatic Neoplasms; Protein Kinase C; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Survival Analysis; Tight Junctions; Tyrosine; Up-Regulation

2016
Cathepsin X Cleaves Profilin 1 C-Terminal Tyr139 and Influences Clathrin-Mediated Endocytosis.
    PloS one, 2015, Volume: 10, Issue:9

    Topics: Cathepsin Z; Cell Line, Tumor; Clathrin; Endocytosis; Gene Expression; Humans; Neoplasm Invasiveness; Neoplasm Metastasis; Polymerization; Profilins; Proteolysis; Tyrosine

2015
Extracellular matrix-specific Caveolin-1 phosphorylation on tyrosine 14 is linked to augmented melanoma metastasis but not tumorigenesis.
    Oncotarget, 2016, Jun-28, Volume: 7, Issue:26

    Topics: Animals; Carcinogenesis; Caveolin 1; Cell Adhesion; Cell Movement; Female; Fibroblasts; Fibronectins; Humans; Integrin beta1; Laminin; Lung Neoplasms; Male; Melanoma; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Neoplasm Invasiveness; Neoplasm Metastasis; Phosphorylation; Skin Neoplasms; Tyrosine

2016
Nuclearly translocated insulin-like growth factor 1 receptor phosphorylates histone H3 at tyrosine 41 and induces SNAI2 expression via Brg1 chromatin remodeling protein.
    Oncotarget, 2016, Jul-05, Volume: 7, Issue:27

    Topics: Active Transport, Cell Nucleus; Cell Line, Tumor; Cell Nucleus; Chromatin; Chromatin Assembly and Disassembly; DNA Helicases; DNA, Complementary; HeLa Cells; Histones; Humans; Ligands; Neoplasm Invasiveness; Neoplasm Metastasis; Nuclear Proteins; Phosphorylation; Protein Binding; Receptor, IGF Type 1; Receptors, Somatomedin; Snail Family Transcription Factors; Transcription Factors; Tyrosine

2016
Dynamic O-(2-[18F]fluoroethyl)-L-tyrosine PET imaging for the detection of checkpoint inhibitor-related pseudoprogression in melanoma brain metastases.
    Neuro-oncology, 2016, Volume: 18, Issue:10

    Topics: Brain Neoplasms; Humans; Melanoma; Neoplasm Metastasis; Positron-Emission Tomography; Radiopharmaceuticals; Tyrosine

2016
c-Src phosphorylation and activation of hexokinase promotes tumorigenesis and metastasis.
    Nature communications, 2017, 01-05, Volume: 8

    Topics: Animals; Carcinogenesis; Cell Line, Tumor; Cell Proliferation; Enzyme Activation; Glucose; Glucose-6-Phosphate; Glycolysis; Heterografts; Hexokinase; Humans; Kinetics; Male; Metabolic Networks and Pathways; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Metastasis; Neoplasms; Phosphorylation; Protein Binding; Proto-Oncogene Proteins pp60(c-src); Tyrosine

2017
Shp2 Plays a Critical Role in IL-6-Induced EMT in Breast Cancer Cells.
    International journal of molecular sciences, 2017, Feb-13, Volume: 18, Issue:2

    Topics: Animals; Biomarkers; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Disease Models, Animal; Epithelial-Mesenchymal Transition; Female; Gene Expression; Gene Knockdown Techniques; Humans; Interleukin-6; Mice; Mutation; Neoplasm Metastasis; Phosphoric Monoester Hydrolases; Phosphorylation; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Tumor Burden; Tyrosine

2017
Inhibition of STAT3 Tyr705 phosphorylation by Smad4 suppresses transforming growth factor beta-mediated invasion and metastasis in pancreatic cancer cells.
    Cancer research, 2008, Jun-01, Volume: 68, Issue:11

    Topics: Blotting, Western; Cell Line, Tumor; Extracellular Signal-Regulated MAP Kinases; Humans; Neoplasm Invasiveness; Neoplasm Metastasis; Pancreatic Neoplasms; Phosphorylation; Smad4 Protein; STAT3 Transcription Factor; Transforming Growth Factor beta; Tyrosine

2008
BKM1740, an acyl-tyrosine bisphosphonate amide derivative, inhibits the bone metastatic growth of human prostate cancer cells by inducing apoptosis.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2008, Oct-01, Volume: 14, Issue:19

    Topics: Amides; Animals; Antineoplastic Agents; Apoptosis; Bone Neoplasms; Cell Line, Tumor; Cell Proliferation; Culture Media, Conditioned; Diphosphonates; Flow Cytometry; Humans; Male; Mice; Neoplasm Metastasis; Neoplasm Transplantation; Prostatic Neoplasms; Tyrosine

2008
Beta-arrestin links endothelin A receptor to beta-catenin signaling to induce ovarian cancer cell invasion and metastasis.
    Proceedings of the National Academy of Sciences of the United States of America, 2009, Feb-24, Volume: 106, Issue:8

    Topics: Arrestins; beta Catenin; beta-Arrestin 1; beta-Arrestin 2; beta-Arrestins; Blotting, Western; Cell Line, Tumor; ErbB Receptors; Female; Humans; Microscopy, Fluorescence; Neoplasm Invasiveness; Neoplasm Metastasis; Ovarian Neoplasms; Phosphorylation; Receptor, Endothelin A; Signal Transduction; Transcriptional Activation; Transplantation, Heterologous; Tyrosine

2009
Tyrosine phosphorylation of PP2A is regulated by HER-2 signalling and correlates with breast cancer progression.
    International journal of oncology, 2009, Volume: 34, Issue:5

    Topics: Biomarkers, Tumor; Breast Neoplasms; Disease Progression; Humans; Neoplasm Invasiveness; Neoplasm Metastasis; Neuregulin-1; Phosphorylation; Prognosis; Protein Phosphatase 2; Protein-Tyrosine Kinases; Receptor, ErbB-2; Signal Transduction; Tissue Array Analysis; Tumor Cells, Cultured; Tyrosine

2009
FAK phosphorylation by ERK primes ras-induced tyrosine dephosphorylation of FAK mediated by PIN1 and PTP-PEST.
    Molecular cell, 2009, Jul-10, Volume: 35, Issue:1

    Topics: Animals; Binding Sites; Cell Line; Cell Line, Tumor; Cell Movement; Focal Adhesion Protein-Tyrosine Kinases; Humans; Immunoblotting; Mice; Mice, Nude; Mitogen-Activated Protein Kinases; Neoplasm Metastasis; Neoplasm Transplantation; Neoplasms, Experimental; NIH 3T3 Cells; NIMA-Interacting Peptidylprolyl Isomerase; Peptidylprolyl Isomerase; Phosphorylation; Protein Binding; Protein Tyrosine Phosphatase, Non-Receptor Type 12; ras Proteins; Serine; Transfection; Tyrosine

2009
Identification of tyrosine-phosphorylated proteins associated with metastasis and functional analysis of FER in human hepatocellular carcinoma cells.
    BMC cancer, 2009, Oct-16, Volume: 9

    Topics: Carcinoma, Hepatocellular; Cell Line, Tumor; Humans; Liver Neoplasms; Neoplasm Metastasis; Phosphoproteins; Phosphorylation; Protein Binding; Protein-Tyrosine Kinases; Tyrosine

2009
Bee venom inhibits tumor angiogenesis and metastasis by inhibiting tyrosine phosphorylation of VEGFR-2 in LLC-tumor-bearing mice.
    Cancer letters, 2010, Jun-01, Volume: 292, Issue:1

    Topics: Animals; Bee Venoms; Carcinoma, Lewis Lung; Cell Movement; Cell Survival; Male; Mice; Mice, Inbred C57BL; Neoplasm Metastasis; Neovascularization, Pathologic; Phosphorylation; Protein Tyrosine Phosphatases; Signal Transduction; Tumor Cells, Cultured; Tyrosine; Vascular Endothelial Growth Factor Receptor-2

2010
Identification of tyrosine-phosphorylated proteins associated with lung cancer metastasis using label-free quantitative analyses.
    Journal of proteome research, 2010, Aug-06, Volume: 9, Issue:8

    Topics: Alkaline Phosphatase; Blotting, Western; Cell Line, Tumor; Chromatography, Liquid; Computational Biology; ErbB Receptors; Humans; Immunoprecipitation; Janus Kinase 2; Lung Neoplasms; Neoplasm Metastasis; Phosphoproteins; Phosphorylation; Protein Tyrosine Phosphatase, Non-Receptor Type 2; Proteomics; src-Family Kinases; Tandem Mass Spectrometry; Titanium; Tyrosine

2010
Epithelial-to-mesenchymal transition promotes tubulin detyrosination and microtentacles that enhance endothelial engagement.
    Cancer research, 2010, Oct-15, Volume: 70, Issue:20

    Topics: Biopsy; Breast Neoplasms; Cell Adhesion; Cytoskeleton; Epithelium; Female; Humans; Immunohistochemistry; Mesoderm; Neoplasm Invasiveness; Neoplasm Metastasis; Nuclear Proteins; Tubulin; Twist-Related Protein 1; Tyrosine

2010
MUC1 enhances invasiveness of pancreatic cancer cells by inducing epithelial to mesenchymal transition.
    Oncogene, 2011, Mar-24, Volume: 30, Issue:12

    Topics: Amino Acid Sequence; Animals; Cadherins; Cell Line, Tumor; Epithelial-Mesenchymal Transition; Humans; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Mucin-1; Neoplasm Invasiveness; Neoplasm Metastasis; Pancreatic Neoplasms; Snail Family Transcription Factors; Transcription Factors; Tyrosine

2011
Tyrosine 23 phosphorylation-dependent cell-surface localization of annexin A2 is required for invasion and metastases of pancreatic cancer.
    PloS one, 2011, Apr-29, Volume: 6, Issue:4

    Topics: Animals; Annexin A2; Antibodies, Monoclonal; Antigens, Neoplasm; Biomarkers, Tumor; Blotting, Western; Cancer Vaccines; Cell Line, Tumor; Cell Membrane; Cell Movement; Disease-Free Survival; Epithelial-Mesenchymal Transition; Female; Humans; Liver; Mice; Mice, Inbred C57BL; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasms, Experimental; Pancreatic Neoplasms; Phosphorylation; RNA Interference; Tumor Cells, Cultured; Tyrosine

2011
Phosphoinositide 3-kinase signaling is critical for ErbB3-driven breast cancer cell motility and metastasis.
    Oncogene, 2012, Feb-09, Volume: 31, Issue:6

    Topics: Animals; Binding Sites; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Female; Humans; Hydrazones; Immunoprecipitation; Mammary Neoplasms, Animal; Mice; Mice, SCID; Microscopy, Fluorescence, Multiphoton; Mutation; Neoplasm Invasiveness; Neoplasm Metastasis; Neuregulin-1; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Binding; Rats; Receptor, ErbB-3; Signal Transduction; Sulfonamides; Transplantation, Heterologous; Tyrosine

2012
Downregulation of TFPI in breast cancer cells induces tyrosine phosphorylation signaling and increases metastatic growth by stimulating cell motility.
    BMC cancer, 2011, Aug-17, Volume: 11

    Topics: Breast Neoplasms; Cell Adhesion; Cell Line, Tumor; Cell Movement; Collagen Type I; Down-Regulation; Doxycycline; Female; Gene Expression Regulation, Neoplastic; Humans; Integrin alpha2; Lipoproteins; Matrix Metalloproteinases; Microscopy, Fluorescence; Neoplasm Invasiveness; Neoplasm Metastasis; Phosphorylation; Plasminogen Activators; Protein Isoforms; RNA Interference; Signal Transduction; Tyrosine

2011
Nck2 promotes human melanoma cell proliferation, migration and invasion in vitro and primary melanoma-derived tumor growth in vivo.
    BMC cancer, 2011, Oct-12, Volume: 11

    Topics: Adaptor Proteins, Signal Transducing; Animals; Cell Adhesion; Cell Adhesion Molecules; Cell Line, Transformed; Cell Line, Tumor; Cell Movement; Cell Proliferation; Gene Expression Regulation, Neoplastic; HEK293 Cells; Humans; Melanoma; Mice; Mice, Nude; Neoplasm Invasiveness; Neoplasm Metastasis; Oncogene Proteins; Phosphorylation; RNA, Messenger; Signal Transduction; Tumor Burden; Tyrosine; Xenograft Model Antitumor Assays

2011
ACAP4 protein cooperates with Grb2 protein to orchestrate epidermal growth factor-stimulated integrin β1 recycling in cell migration.
    The Journal of biological chemistry, 2011, Dec-23, Volume: 286, Issue:51

    Topics: ADP-Ribosylation Factor 6; ADP-Ribosylation Factors; Animals; Cell Membrane; Cell Movement; Chlorocebus aethiops; COS Cells; Cytoskeletal Proteins; Cytoskeleton; Epidermal Growth Factor; GRB2 Adaptor Protein; GTPase-Activating Proteins; HeLa Cells; Humans; Integrin beta1; Integrins; Neoplasm Metastasis; Phosphorylation; Tyrosine

2011
EphB3 suppresses non-small-cell lung cancer metastasis via a PP2A/RACK1/Akt signalling complex.
    Nature communications, 2012, Feb-07, Volume: 3

    Topics: Animals; Carcinoma, Non-Small-Cell Lung; Cell Movement; Gene Expression Regulation, Neoplastic; GTP-Binding Proteins; HEK293 Cells; Humans; Ligands; Lung Neoplasms; Mice; Mice, Nude; Models, Biological; Mutation; Neoplasm Metastasis; Neoplasm Proteins; Neoplasm Transplantation; Neuropeptides; Phosphorylation; Photons; Proto-Oncogene Proteins c-akt; Receptor, EphB3; Receptors for Activated C Kinase; Receptors, Cell Surface; Signal Transduction; Tyrosine

2012
Ezrin phosphorylation on tyrosine 477 regulates invasion and metastasis of breast cancer cells.
    BMC cancer, 2012, Mar-07, Volume: 12

    Topics: Animals; Blotting, Western; Breast Neoplasms; Carcinoma; Cell Movement; Cytoskeletal Proteins; Female; Mice; Mice, Nude; Neoplasm Invasiveness; Neoplasm Metastasis; Phosphorylation; Tumor Cells, Cultured; Tyrosine

2012
EMT phenotype is induced by increased Src kinase activity via Src-mediated caspase-8 phosphorylation.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2012, Volume: 29, Issue:3-4

    Topics: Animals; Binding Sites; Caspase 8; Cell Line, Tumor; Cell Migration Assays; Enzyme Activation; Epithelial-Mesenchymal Transition; Fluorescent Antibody Technique; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Genetic Vectors; Humans; Integrin alphaV; Integrin beta4; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Metastasis; Phenotype; Phosphorylation; Protein Binding; Protein Conformation; src Homology Domains; src-Family Kinases; Tyrosine; Xenograft Model Antitumor Assays

2012
Identification of molecular switch regulating interactions of Janus kinase 3 with cytoskeletal proteins.
    The Journal of biological chemistry, 2012, Nov-30, Volume: 287, Issue:49

    Topics: Cell Line, Tumor; Cell Movement; Cytoskeleton; Gene Expression Regulation, Enzymologic; Humans; Janus Kinase 3; Kinetics; Microfilament Proteins; Mutagenesis; Neoplasm Metastasis; Phosphorylation; Protein Structure, Tertiary; Recombinant Proteins; src Homology Domains; Tyrosine; Wound Healing

2012
Src activation by β-adrenoreceptors is a key switch for tumour metastasis.
    Nature communications, 2013, Volume: 4

    Topics: Adrenergic beta-Antagonists; Animals; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Enzyme Activation; Female; Humans; Mice; Models, Molecular; Neoplasm Invasiveness; Neoplasm Metastasis; Norepinephrine; Ovarian Neoplasms; Phosphorylation; Phosphoserine; Receptors, Adrenergic, beta; Signal Transduction; src-Family Kinases; Stress, Physiological; Survival Analysis; Tyrosine

2013
Ipriflavone inhibits osteolytic bone metastasis of human breast cancer cells in a nude mouse model.
    International journal of cancer, 2002, Aug-01, Volume: 100, Issue:4

    Topics: Analgesics; Animals; Antineoplastic Agents; Apoptosis; Bone Neoplasms; Breast Neoplasms; Cell Division; Disease Models, Animal; Disease Progression; ErbB Receptors; Female; Isoflavones; Mice; Mice, Inbred ICR; Mice, Nude; Mitotic Index; Neoplasm Metastasis; Osteoclasts; Phosphorylation; Treatment Outcome; Tyrosine

2002
Anchorage-independent phosphorylation of p130(Cas) protects lung adenocarcinoma cells from anoikis.
    Journal of cellular biochemistry, 2002, Volume: 87, Issue:4

    Topics: Adenocarcinoma; Animals; Anoikis; Apoptosis; Bronchi; Cell Line; Cell Survival; Crk-Associated Substrate Protein; Dogs; Dose-Response Relationship, Drug; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Humans; Immunoblotting; Lung Neoplasms; Neoplasm Metastasis; Phosphoproteins; Phosphorylation; Plasmids; Precipitin Tests; Protein-Tyrosine Kinases; Proteins; Retinoblastoma-Like Protein p130; Signal Transduction; src-Family Kinases; Transfection; Tumor Cells, Cultured; Tyrosine

2002
Specific amino acid dependency regulates invasiveness and viability of androgen-independent prostate cancer cells.
    Nutrition and cancer, 2003, Volume: 45, Issue:1

    Topics: Amino Acids; Androgens; Animals; Apoptosis; Cell Adhesion; Cell Cycle; Cell Division; Cell Line, Tumor; DNA Fragmentation; Flow Cytometry; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Humans; Male; Mitogen-Activated Protein Kinases; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Proteins; Phenylalanine; Phosphorylation; Prostatic Neoplasms; Protein-Tyrosine Kinases; Tyrosine

2003
Enhancement of cisplatin-induced cytotoxicity by ROCK inhibitor through suppression of focal adhesion kinase-independent mechanism in lung carcinoma cells.
    International journal of oncology, 2003, Volume: 23, Issue:4

    Topics: Amides; Blotting, Western; Carcinoma; Cell Line, Tumor; Cisplatin; Dose-Response Relationship, Drug; Enzyme Inhibitors; Flow Cytometry; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Humans; Intracellular Signaling Peptides and Proteins; Lung Neoplasms; Neoplasm Metastasis; Phosphorylation; Plasmids; Precipitin Tests; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Pyridines; rho-Associated Kinases; Signal Transduction; Time Factors; Transfection; Tyrosine

2003
FUNCTIONING FOLLICULAR METASTATIC CARCINOMA OF THE THYROID.
    The Medical journal of Australia, 1964, Oct-31, Volume: 2

    Topics: Carcinoma; Humans; Iodine Isotopes; Neoplasm Metastasis; Neoplasms; Pathology; Pharmacology; Thoracic Neoplasms; Thyroid Function Tests; Thyroid Neoplasms; Thyroidectomy; Thyroxine; Tyrosine

1964
[TYROSINE DEMONSTRATION IN METASTASES OF MALIGNANT MELANOMA. A METHOD OF DIFFERENTIATION OF SATELLITES OF SO-CALLED INDUCED OR MULTIPLE PRIMARY MELANOMA OF THE SKIN].
    Archiv fur klinische und experimentelle Dermatologie, 1964, Oct-20, Volume: 220

    Topics: Cell Differentiation; Humans; Melanoma; Neoplasm Metastasis; Neoplasms, Second Primary; Skin Neoplasms; Tyrosine; Tyrosine Decarboxylase

1964
Evaluation of the serum L-dopa/L-tyrosine ratio as a melanoma marker.
    Melanoma research, 2003, Volume: 13, Issue:6

    Topics: Adult; Biomarkers, Tumor; Cell Line, Tumor; Chromatography, High Pressure Liquid; Female; Humans; Levodopa; Lymph Node Excision; Lymphatic Metastasis; Male; Melanoma; Middle Aged; Neoplasm Metastasis; Nerve Growth Factors; Prognosis; Recurrence; S100 Calcium Binding Protein beta Subunit; S100 Proteins; Time Factors; Tyrosine

2003
Regulation of CXCR4-mediated chemotaxis and chemoinvasion of breast cancer cells.
    Oncogene, 2004, Jan-08, Volume: 23, Issue:1

    Topics: Breast Neoplasms; Cell Adhesion; Cell Line, Tumor; Chemokine CXCL12; Chemokines, CXC; Chemotaxis; Female; Focal Adhesion Kinase 1; Focal Adhesion Kinase 2; Focal Adhesion Protein-Tyrosine Kinases; Humans; Intracellular Signaling Peptides and Proteins; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mitogen-Activated Protein Kinases; Neoplasm Invasiveness; Neoplasm Metastasis; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Receptors, CXCR4; Tyrosine

2004
Inhibition of SRC tyrosine kinase impairs inherent and acquired gemcitabine resistance in human pancreatic adenocarcinoma cells.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Apr-01, Volume: 10, Issue:7

    Topics: Adenocarcinoma; Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Apoptosis; Blotting, Northern; Blotting, Western; Caspases; Cell Cycle Proteins; Cell Division; Cell Line, Tumor; Cell Nucleus; Deoxycytidine; DNA-Binding Proteins; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; E2F Transcription Factors; E2F1 Transcription Factor; Gemcitabine; Genes, Dominant; Humans; Inhibitory Concentration 50; Mice; Mice, Nude; Neoplasm Metastasis; Neoplasm Transplantation; Pancreatic Neoplasms; Phosphorylation; Pyrimidines; Ribonucleoside Diphosphate Reductase; src-Family Kinases; Transcription Factors; Tyrosine

2004
Structure of human PRL-3, the phosphatase associated with cancer metastasis.
    FEBS letters, 2004, May-07, Volume: 565, Issue:1-3

    Topics: Amino Acid Sequence; Binding Sites; Enzyme Inhibitors; Humans; Immediate-Early Proteins; Ions; Ligands; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Sequence Data; Neoplasm Metastasis; Neoplasm Proteins; Neoplasms; Phosphates; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Protein Tyrosine Phosphatases; Sequence Homology, Amino Acid; Tyrosine; Vanadates

2004
Imatinib mesylate efficiently achieves therapeutic intratumor concentrations in vivo but has limited activity in a xenograft model of small cell lung cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, May-15, Volume: 10, Issue:10

    Topics: Animals; Antineoplastic Agents; Benzamides; Brain Neoplasms; Carcinoma, Small Cell; Cell Line, Tumor; Humans; Imatinib Mesylate; Immunoblotting; Immunoprecipitation; Ligands; Lung Neoplasms; Mice; Mice, Nude; Neoplasm Metastasis; Neoplasm Transplantation; NIH 3T3 Cells; Phosphorylation; Piperazines; Proto-Oncogene Proteins c-kit; Pyrimidines; Signal Transduction; Stem Cell Factor; Time Factors; Tyrosine

2004
Targeting of HLA-DR molecules transduces agonistic functional signals in cutaneous melanoma.
    Journal of cellular physiology, 2004, Volume: 200, Issue:2

    Topics: Antibodies, Monoclonal; Antigens, Neoplasm; Blotting, Western; Cell Aggregation; Cell Division; Electrophoresis, Polyacrylamide Gel; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; HLA-DR Antigens; Humans; Lymphocyte Activation; Melanoma; Molecular Weight; Neoplasm Metastasis; Phosphorylation; Precipitin Tests; Protein-Tyrosine Kinases; Signal Transduction; Skin Neoplasms; Tumor Cells, Cultured; Tyrosine; Up-Regulation

2004
Selective tyrosine hyperphosphorylation of cytoskeletal and stress proteins in primary human breast cancers: implications for adjuvant use of kinase-inhibitory drugs.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Jun-15, Volume: 10, Issue:12 Pt 1

    Topics: Animals; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Chemotherapy, Adjuvant; Chromatography; Cytoskeleton; Electrophoresis, Gel, Two-Dimensional; Heat-Shock Proteins; Humans; Immunoblotting; Ligands; Male; Mass Spectrometry; Mice; Mice, Inbred BALB C; Neoplasm Metastasis; Neoplasms; Phosphoproteins; Phosphorylation; Phosphotyrosine; Signal Transduction; Tyrosine

2004
Identification and phenotypic characterization of a subpopulation of T84 human colon cancer cells, after selection on activated endothelial cells.
    Journal of cellular physiology, 2005, Volume: 203, Issue:1

    Topics: Animals; Apoptosis; Cell Adhesion; Cell Communication; Cell Division; Cell Line, Tumor; Colonic Neoplasms; Endothelium, Vascular; Enzyme Inhibitors; Humans; Male; Metalloproteases; Mice; Mice, Nude; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Transplantation; Phenotype; Phosphorylation; src-Family Kinases; Tyrosine; Umbilical Veins

2005
CEACAM1 enhances invasion and migration of melanocytic and melanoma cells.
    The American journal of pathology, 2004, Volume: 165, Issue:5

    Topics: Antibodies, Monoclonal; Antigens, CD; Antigens, Differentiation; Blotting, Western; Cell Adhesion; Cell Adhesion Molecules; Cell Line, Tumor; Cell Movement; Cytoplasm; DNA, Complementary; Dose-Response Relationship, Drug; Humans; Integrin alphaVbeta3; Integrin beta3; Melanocytes; Melanoma; Neoplasm Invasiveness; Neoplasm Metastasis; Oligonucleotide Array Sequence Analysis; Oligopeptides; Protein Structure, Tertiary; Time Factors; Transfection; Tyrosine; Up-Regulation

2004
17beta-Estradiol upregulates and activates WOX1/WWOXv1 and WOX2/WWOXv2 in vitro: potential role in cancerous progression of breast and prostate to a premetastatic state in vivo.
    Oncogene, 2005, Jan-20, Volume: 24, Issue:4

    Topics: Animals; Breast Neoplasms; Cell Line; Chlorocebus aethiops; Disease Progression; Estradiol; Humans; Hyperplasia; Male; Mice; Mitochondria; Neoplasm Metastasis; Oxidoreductases; Phosphorylation; Prostatic Neoplasms; Protein Binding; Protein Transport; Receptors, Androgen; Tumor Suppressor Protein p53; Tumor Suppressor Proteins; Tyrosine; Up-Regulation; WW Domain-Containing Oxidoreductase

2005
Focal adhesion kinase regulates metastatic adhesion of carcinoma cells within liver sinusoids.
    The American journal of pathology, 2005, Volume: 166, Issue:2

    Topics: Animals; Carcinoma; Carcinoma, Hepatocellular; Cell Adhesion; Cell Line, Tumor; Collagen; Colon; Cytoskeletal Proteins; Dose-Response Relationship, Drug; Endothelium, Vascular; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Humans; Immunoprecipitation; Liver; Liver Neoplasms; Male; Microcirculation; Microscopy, Fluorescence; Neoplasm Metastasis; Neoplasms; Oligonucleotides; Paxillin; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Time Factors; Transfection; Tyrosine

2005
Correlation between 99mTc-(V)-DMSA uptake and constitutive level of phosphorylated focal adhesion kinase in an in vitro model of cancer cell lines.
    European journal of nuclear medicine and molecular imaging, 2005, Volume: 32, Issue:7

    Topics: Antineoplastic Agents; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Focal Adhesion Protein-Tyrosine Kinases; Humans; In Vitro Techniques; Ions; Kinetics; Neoplasm Invasiveness; Neoplasm Metastasis; Phosphates; Phosphorylation; Prognosis; Radiopharmaceuticals; Technetium Tc 99m Dimercaptosuccinic Acid; Time Factors; Tyrosine

2005
Involvement of reactive nitrogen oxides for acquisition of metastatic properties of benign tumors in a model of inflammation-based tumor progression.
    Nitric oxide : biology and chemistry, 2006, Volume: 14, Issue:2

    Topics: Animals; Cell Movement; Cell Proliferation; Disease Progression; Female; Fibrosarcoma; Gelatin Sponge, Absorbable; Guanidine; Guanine; Inflammation; Mice; Mice, Inbred C57BL; Neoplasm Metastasis; Neoplasm Transplantation; Nitric Oxide Synthase Type II; Oxidation-Reduction; Reactive Nitrogen Species; Tyrosine

2006
Mechanisms of plakoglobin-dependent adhesion: desmosome-specific functions in assembly and regulation by epidermal growth factor receptor.
    The Journal of biological chemistry, 2005, Dec-02, Volume: 280, Issue:48

    Topics: Adenoviridae; Adherens Junctions; Animals; beta Catenin; Blotting, Western; Cell Adhesion; Cells, Cultured; Desmosomes; Detergents; Dose-Response Relationship, Drug; Epidermal Growth Factor; ErbB Receptors; gamma Catenin; Green Fluorescent Proteins; Immunoprecipitation; Keratinocytes; Mice; Mice, Knockout; Microscopy, Fluorescence; Neoplasm Metastasis; Octoxynol; Phosphorylation; Protein Structure, Tertiary; Signal Transduction; Time Factors; Tyrosine; Wound Healing

2005
Regulation of the wild-type and Y1235D mutant Met kinase activation.
    Biochemistry, 2005, Nov-01, Volume: 44, Issue:43

    Topics: Animals; Aspartic Acid; Base Sequence; Binding Sites; Carbazoles; Enzyme Inhibitors; Gene Silencing; Humans; Indole Alkaloids; Kinetics; Mutation; Neoplasm Metastasis; Phenotype; Phosphorylation; Phosphotyrosine; Protein Conformation; Proto-Oncogene Proteins c-met; Receptor Protein-Tyrosine Kinases; Recombinant Proteins; Transduction, Genetic; Tumor Cells, Cultured; Tyrosine

2005
Gastrointestinal stromal tumors: insights from a new familial GIST kindred with unusual genetic and pathologic features.
    The American journal of surgical pathology, 2005, Volume: 29, Issue:12

    Topics: Adult; Alleles; Amino Acid Substitution; Coiled Bodies; Colectomy; DNA Mutational Analysis; DNA, Neoplasm; Exons; Gastrectomy; Gastrointestinal Stromal Tumors; Germ-Line Mutation; Hepatectomy; Heterozygote; Histocytochemistry; Homozygote; Humans; Hyperplasia; Immunohistochemistry; Laparotomy; Liver; Male; Neoplasm Metastasis; Pancreaticoduodenectomy; Pedigree; Point Mutation; Proto-Oncogene Proteins c-kit; Sequence Analysis, DNA; Tomography, X-Ray Computed; Tumor Burden; Tyrosine

2005
Photodynamic therapy suppresses the migration and invasion of head and neck cancer cells in vitro.
    Oral oncology, 2007, Volume: 43, Issue:4

    Topics: Aminolevulinic Acid; Cell Line, Tumor; Cell Movement; Cell Survival; Collagen; Drug Combinations; Extracellular Signal-Regulated MAP Kinases; Focal Adhesion Protein-Tyrosine Kinases; Head and Neck Neoplasms; Humans; Laminin; Light; Neoplasm Invasiveness; Neoplasm Metastasis; Phosphorylation; Photochemotherapy; Photosensitizing Agents; Proteoglycans; Signal Transduction; src-Family Kinases; Tyrosine

2007
Autocrine growth hormone: effects on growth hormone receptor trafficking and signaling.
    Molecular endocrinology (Baltimore, Md.), 2007, Volume: 21, Issue:11

    Topics: Biological Transport; Cell Line, Tumor; Cell Proliferation; Growth Hormone; Humans; Models, Biological; Mutation; Neoplasm Metastasis; Phosphorylation; Protein Binding; Receptors, Somatotropin; Signal Transduction; STAT5 Transcription Factor; Tyrosine

2007
Grb2 binding to Tyr284 in TbetaR-II is essential for mammary tumor growth and metastasis stimulated by TGF-beta.
    Carcinogenesis, 2008, Volume: 29, Issue:2

    Topics: Animals; Cell Proliferation; Female; GRB2 Adaptor Protein; Humans; Mammary Neoplasms, Animal; MAP Kinase Signaling System; Mice; Mice, Inbred BALB C; Neoplasm Metastasis; Neoplasm Transplantation; Phosphotransferases; Protein Serine-Threonine Kinases; Receptor, Transforming Growth Factor-beta Type II; Receptors, Transforming Growth Factor beta; src-Family Kinases; Transforming Growth Factor beta; Tyrosine

2008
Pressure activates colon cancer cell adhesion via paxillin phosphorylation, Crk, Cas, and Rac1.
    Cellular and molecular life sciences : CMLS, 2008, Volume: 65, Issue:9

    Topics: Actinin; Cell Adhesion; Cell Line, Tumor; Colonic Neoplasms; Crk-Associated Substrate Protein; Humans; Neoplasm Metastasis; Paxillin; Phosphorylation; Pressure; Proto-Oncogene Proteins c-crk; rac1 GTP-Binding Protein; RNA Interference; Tumor Cells, Cultured; Tyrosine

2008
Crystal structure of the Ca(2+)-form and Ca(2+)-binding kinetics of metastasis-associated protein, S100A4.
    FEBS letters, 2008, May-28, Volume: 582, Issue:12

    Topics: Amino Acid Sequence; Calcium; Crystallography, X-Ray; Fluorescence; Humans; Kinetics; Ligands; Molecular Sequence Data; Neoplasm Metastasis; Protein Binding; Protein Conformation; S100 Calcium-Binding Protein A4; S100 Proteins; Tyrosine

2008
Evaluation of transsphenoidal hypophysectomy in the management of patients with advanced malignant melanoma.
    Cancer, 1983, Apr-15, Volume: 51, Issue:8

    Topics: Adult; Evaluation Studies as Topic; Female; Humans; Hypophysectomy; Male; Melanoma; Methyltyrosines; Middle Aged; Neoplasm Metastasis; Palliative Care; Postoperative Complications; Prognosis; Radioimmunoassay; Skin Neoplasms; Tyrosine

1983
Evidence for nutrient modulation of tumor phenotype: impact of tyrosine and phenylalanine restriction.
    Advances in experimental medicine and biology, 1994, Volume: 354

    Topics: Animal Nutritional Physiological Phenomena; Animals; Diet; Female; Killer Cells, Natural; Lung; Mast Cells; Melanoma, Experimental; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Metastasis; Neoplasm Transplantation; Neovascularization, Pathologic; Phenotype; Phenylalanine; Tumor Cells, Cultured; Tyrosine

1994
Brain tumors: L-[1-C-11]tyrosine PET for visualization and quantification of protein synthesis rate.
    Radiology, 1995, Volume: 197, Issue:1

    Topics: Adult; Aged; Brain Neoplasms; Carbon Radioisotopes; Female; Glioma; Humans; Lymphoma, Non-Hodgkin; Male; Meningioma; Methionine; Middle Aged; Neoplasm Metastasis; Neoplasm Proteins; Tomography, Emission-Computed; Tyrosine; Vasculitis

1995
Differential transforming abilities of non-secreted and secreted forms of human fibroblast growth factor-1.
    The Journal of biological chemistry, 1993, Feb-05, Volume: 268, Issue:4

    Topics: 3T3 Cells; Amino Acid Sequence; Animals; Base Sequence; Cell Division; Cell Transformation, Neoplastic; Fibroblast Growth Factors; Genetic Vectors; In Vitro Techniques; Mice; Mice, Nude; Molecular Sequence Data; Neoplasm Metastasis; Neoplasms, Experimental; Oligodeoxyribonucleotides; Phosphotyrosine; Protein Sorting Signals; Protein-Tyrosine Kinases; Recombinant Fusion Proteins; Structure-Activity Relationship; Transfection; Tyrosine

1993
Phorbol 12-myristate 13-acetate enhances nm23 gene expression in murine melanocytes but not in syngeneic B16-BL6 melanoma variants.
    Journal of cellular physiology, 1996, Volume: 166, Issue:3

    Topics: Animals; Cell Division; Cell Membrane; Cytosol; Female; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Melanocytes; Melanoma, Experimental; Mice; Monomeric GTP-Binding Proteins; Neoplasm Metastasis; NM23 Nucleoside Diphosphate Kinases; Nucleoside-Diphosphate Kinase; Phenylalanine; Protein Kinase C; RNA, Messenger; RNA, Neoplasm; Tetradecanoylphorbol Acetate; Transcription Factors; Tumor Cells, Cultured; Tyrosine

1996
Attachment, invasion, chemotaxis, and proteinase expression of B16-BL6 melanoma cells exhibiting a low metastatic phenotype after exposure to dietary restriction of tyrosine and phenylalanine.
    Clinical & experimental metastasis, 1996, Volume: 14, Issue:2

    Topics: Animals; Cell Adhesion; Chemotaxis; Diet; Melanoma, Experimental; Metalloendopeptidases; Mice; Neoplasm Invasiveness; Neoplasm Metastasis; Phenylalanine; Plasminogen Activators; Receptors, Fibronectin; Tyrosine

1996
Inhibition of in vitro tumor cell invasion by ginsenoside Rg3.
    Japanese journal of cancer research : Gann, 1996, Volume: 87, Issue:4

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Carbohydrate Sequence; Carcinoma, Small Cell; Ginsenosides; Humans; Liver Neoplasms, Experimental; Lung Neoplasms; Lysophospholipids; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Proteins; Pancreatic Neoplasms; Phosphorylation; Rats; Rats, Inbred Strains; Saponins; Tyrosine

1996
Dominant negative inhibition of the association between beta-catenin and c-erbB-2 by N-terminally deleted beta-catenin suppresses the invasion and metastasis of cancer cells.
    Oncogene, 1996, Sep-05, Volume: 13, Issue:5

    Topics: Animals; beta Catenin; Cytoskeletal Proteins; Gene Expression Regulation, Neoplastic; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Invasiveness; Neoplasm Metastasis; Phosphorylation; Receptor, ErbB-2; Recombinant Proteins; Sequence Deletion; Signal Transduction; Stomach Neoplasms; Trans-Activators; Transfection; Transforming Growth Factor alpha; Transplantation, Heterologous; Tyrosine

1996
Activation of protein kinase C-alpha isoform in murine melanoma cells with high metastatic potential.
    Clinical & experimental metastasis, 1997, Volume: 15, Issue:6

    Topics: Animals; Cathepsin B; Cell Culture Techniques; DNA, Neoplasm; Enzyme Activation; Isoenzymes; Melanoma, Experimental; Mice; Neoplasm Metastasis; Phenylalanine; Protein Kinase C; Tumor Cells, Cultured; Tyrosine

1997
CAS/Crk coupling serves as a "molecular switch" for induction of cell migration.
    The Journal of cell biology, 1998, Feb-23, Volume: 140, Issue:4

    Topics: Animals; Cell Membrane; Cell Movement; COS Cells; Crk-Associated Substrate Protein; Extracellular Matrix; Gene Expression; GTP-Binding Proteins; Humans; Hypoglycemic Agents; Insulin; Membrane Proteins; Neoplasm Metastasis; Pancreas; Pancreatic Neoplasms; Phosphoproteins; Phosphorylation; Protein Binding; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-crk; Rabbits; rac GTP-Binding Proteins; ras Proteins; Retinoblastoma-Like Protein p130; src Homology Domains; Tumor Cells, Cultured; Tyrosine

1998
A novel variant of human Grb7 is associated with invasive esophageal carcinoma.
    The Journal of clinical investigation, 1998, Aug-15, Volume: 102, Issue:4

    Topics: Adaptor Proteins, Signal Transducing; Alternative Splicing; Amino Acid Sequence; Base Sequence; Carcinoma, Squamous Cell; Cell Movement; ErbB Receptors; Esophageal Neoplasms; GRB2 Adaptor Protein; GRB7 Adaptor Protein; Humans; Molecular Sequence Data; Neoplasm Invasiveness; Neoplasm Metastasis; Phosphorylation; Proteins; RNA, Antisense; Sequence Homology, Amino Acid; Signal Transduction; src Homology Domains; Tumor Cells, Cultured; Tyrosine

1998
Growth factor-dependent activation of alphavbeta3 integrin in normal epithelial cells: implications for tumor invasion.
    The Journal of cell biology, 1998, Aug-24, Volume: 142, Issue:4

    Topics: Antigens, CD; Cell Adhesion; Cell Movement; Clone Cells; Cytokines; Cytoskeleton; Extracellular Matrix; Flow Cytometry; Fluorescent Antibody Technique; Hepatocyte Growth Factor; Humans; Integrin beta1; Integrin beta3; Neoplasm Invasiveness; Neoplasm Metastasis; Phosphorylation; Platelet Membrane Glycoproteins; Proto-Oncogene Proteins c-met; Signal Transduction; Thyroid Gland; Tumor Cells, Cultured; Tyrosine

1998
Signaling requirements for oncogenic forms of the Met tyrosine kinase receptor.
    Oncogene, 1998, Nov-26, Volume: 17, Issue:21

    Topics: 3T3 Cells; Adaptor Proteins, Signal Transducing; Amino Acid Substitution; Animals; Binding Sites; Cell Transformation, Neoplastic; Female; GRB2 Adaptor Protein; Mice; Mice, Nude; Models, Molecular; Mutagenesis, Site-Directed; Neoplasm Metastasis; Oncogenes; Phenylalanine; Point Mutation; Proteins; Proto-Oncogene Proteins c-met; Recombinant Fusion Proteins; Sequence Deletion; Signal Transduction; Structure-Activity Relationship; Tyrosine

1998
Rapid adhesion and spread of non-adherent colon cancer Colo201 cells induced by the protein kinase inhibitors, K252a and KT5720 and suppression of the adhesion by the immunosuppressants FK506 and cyclosporin A.
    Cell structure and function, 1998, Volume: 23, Issue:5

    Topics: Adenocarcinoma; Carbazoles; Cell Adhesion; Cell Adhesion Molecules; Colonic Neoplasms; Cyclosporine; Cytoskeletal Proteins; Enzyme Inhibitors; Extracellular Matrix; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Humans; Immunosuppressive Agents; Indole Alkaloids; Indoles; Integrins; Neoplasm Metastasis; Paxillin; Phosphoproteins; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Pyrroles; Sulfonamides; Tacrolimus; Tumor Cells, Cultured; Tyrosine

1998
Bifurcation of cell migratory and proliferative signaling by the adaptor protein Shc.
    The Journal of cell biology, 1999, Dec-27, Volume: 147, Issue:7

    Topics: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Animals; Cell Division; Cell Line; Cell Movement; COS Cells; DNA Replication; Growth Substances; Humans; Mitosis; Neoplasm Metastasis; Phosphorylation; Proteins; Shc Signaling Adaptor Proteins; Signal Transduction; Src Homology 2 Domain-Containing, Transforming Protein 1; Transfection; Tumor Cells, Cultured; Tyrosine

1999
Expression of the inducible isoform of nitric oxide synthase in pigment cell lesions of the skin.
    The British journal of dermatology, 2000, Volume: 142, Issue:3

    Topics: Biomarkers, Tumor; Disease Progression; Enzyme Induction; Humans; Isoenzymes; Macrophages; Melanoma; Neoplasm Metastasis; Nevus; Nitric Oxide Synthase; Skin Neoplasms; Tyrosine

2000
Inhibition of growth and metastatic progression of pancreatic carcinoma in hamster after somatostatin receptor subtype 2 (sst2) gene expression and administration of cytotoxic somatostatin analog AN-238.
    Proceedings of the National Academy of Sciences of the United States of America, 2000, Aug-01, Volume: 97, Issue:16

    Topics: Animals; Antibiotics, Antineoplastic; Cadherins; Cell Division; Cricetinae; Cytotoxins; Doxorubicin; Fungal Proteins; GTPase-Activating Proteins; Intracellular Signaling Peptides and Proteins; Male; Mesocricetus; Neoplasm Metastasis; Pancreatic Neoplasms; Phosphorylation; Protein Phosphatase 1; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Pyrroles; Saccharomyces cerevisiae Proteins; Tumor Cells, Cultured; Tyrosine

2000
Constitutive tyrosine phosphorylation of ErbB-2 via Jak2 by autocrine secretion of prolactin in human breast cancer.
    The Journal of biological chemistry, 2000, Oct-27, Volume: 275, Issue:43

    Topics: Adaptor Proteins, Signal Transducing; Breast Neoplasms; Cell Division; Female; GRB2 Adaptor Protein; Humans; Janus Kinase 2; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Neoplasm Metastasis; Phosphorylation; Prolactin; Protein-Tyrosine Kinases; Proteins; Proto-Oncogene Proteins; Receptor, ErbB-2; Tyrosine

2000
Inducible nitric oxide synthase and nitrotyrosine in human metastatic melanoma tumors correlate with poor survival.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2000, Volume: 6, Issue:12

    Topics: Adolescent; Adult; Female; Humans; Immunohistochemistry; Male; Melanoma; Middle Aged; Neoplasm Metastasis; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Prognosis; Time Factors; Treatment Outcome; Tyrosine

2000
Inhibition of endosomal insulin-like growth factor-I processing by cysteine proteinase inhibitors blocks receptor-mediated functions.
    The Journal of biological chemistry, 2001, Apr-27, Volume: 276, Issue:17

    Topics: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Animals; Blotting, Western; Cell Membrane; Chromatography, High Pressure Liquid; Cysteine Proteinase Inhibitors; Dipeptides; DNA; Dose-Response Relationship, Drug; Endosomes; Female; Flow Cytometry; Humans; Insulin-Like Growth Factor I; Kinetics; Leucine; Ligands; Liver; Male; Mice; Models, Biological; Neoplasm Metastasis; Phosphorylation; Precipitin Tests; Protein Binding; Proteins; Rats; Rats, Sprague-Dawley; Receptor, IGF Type 1; Shc Signaling Adaptor Proteins; Signal Transduction; Src Homology 2 Domain-Containing, Transforming Protein 1; Time Factors; Tumor Cells, Cultured; Tyrosine

2001
Cooperative regulation of the invasive and metastatic phenotypes by different domains of the type I insulin-like growth factor receptor beta subunit.
    The Journal of biological chemistry, 2001, Sep-07, Volume: 276, Issue:36

    Topics: Cell Movement; Cloning, Molecular; DNA Mutational Analysis; DNA, Complementary; Dose-Response Relationship, Drug; Gene Expression Regulation, Neoplastic; Genes, Dominant; Humans; Insulin-Like Growth Factor I; Kinetics; Matrix Metalloproteinase 2; Mutagenesis, Site-Directed; Mutation; Neoplasm Invasiveness; Neoplasm Metastasis; Phenotype; Protein Structure, Tertiary; Receptor, IGF Type 1; Signal Transduction; Time Factors; Transfection; Tumor Cells, Cultured; Tyrosine

2001
Atypical protein kinase Czeta suppresses migration of mouse melanoma cells.
    Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, 2001, Volume: 12, Issue:10

    Topics: Animals; Apoptosis Regulatory Proteins; Blotting, Western; Carrier Proteins; Cell Adhesion; Cell Line; Cell Movement; Cell Separation; Cells, Cultured; DNA, Complementary; Down-Regulation; Intracellular Signaling Peptides and Proteins; Melanins; Melanoma, Experimental; Mice; Mutagenesis, Site-Directed; Neoplasm Metastasis; Phenylalanine; Precipitin Tests; Protein Kinase C; Structure-Activity Relationship; Transfection; Tumor Cells, Cultured; Tyrosine

2001
Ovarian epithelial carcinoma tyrosine phosphorylation, cell proliferation, and ezrin translocation are stimulated by interleukin 1alpha and epidermal growth factor.
    Cancer, 2001, Dec-15, Volume: 92, Issue:12

    Topics: Blotting, Western; Carcinoma; Cell Division; Cytoskeletal Proteins; Epidermal Growth Factor; Female; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Interleukin-1; Neoplasm Invasiveness; Neoplasm Metastasis; Ovarian Neoplasms; Phenotype; Phosphoproteins; Phosphorylation; Translocation, Genetic; Tumor Cells, Cultured; Tyrosine

2001
Inhibition of angiogenesis by the antiepidermal growth factor receptor antibody ImClone C225 in androgen-independent prostate cancer growing orthotopically in nude mice.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2002, Volume: 8, Issue:5

    Topics: Androgens; Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Apoptosis; Blood Vessels; Cell Cycle Proteins; Cell Division; Cetuximab; Cyclin-Dependent Kinase Inhibitor p27; Dose-Response Relationship, Drug; Epidermal Growth Factor; ErbB Receptors; Humans; Interleukin-8; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Metastasis; Neoplasm Transplantation; Neovascularization, Pathologic; Paclitaxel; Phosphorylation; Prostatic Neoplasms; RNA, Messenger; Tumor Cells, Cultured; Tumor Suppressor Proteins; Tyrosine; Up-Regulation; Xenograft Model Antitumor Assays

2002
Acceptability and tolerance of a low tyrosine and phenylalanine diet in patients with advanced cancer -- a pilot study.
    Journal of human nutrition and dietetics : the official journal of the British Dietetic Association, 2002, Volume: 15, Issue:3

    Topics: Adult; Aged; Breast Neoplasms; Depression; Female; Humans; Male; Melanoma; Middle Aged; Neoplasm Metastasis; Nutritional Status; Phenylalanine; Pilot Projects; Quality of Life; Treatment Outcome; Tryptophan; Tyrosine

2002
Demonstration of 3-methoxytyrosine in the urine of melanoma patients.
    Acta dermato-venereologica, 1976, Volume: 56, Issue:1

    Topics: Chromatography, Gas; Dihydroxyphenylalanine; Dopamine; Female; Humans; Male; Mass Spectrometry; Melanoma; Middle Aged; Neoplasm Metastasis; Skin Neoplasms; Tyrosine

1976
Examination of hormonally regulated functions in differentially metastasizing melanoma cells.
    Surgical forum, 1977, Volume: 28

    Topics: Animals; Cell Count; Cell Line; Cyclic AMP; Melanins; Melanocyte-Stimulating Hormones; Melanoma; Mice; Mitosis; Monophenol Monooxygenase; Neoplasm Metastasis; Tyrosine

1977
Cadherin-mediated cell-cell adhesion is perturbed by v-src tyrosine phosphorylation in metastatic fibroblasts.
    The Journal of cell biology, 1992, Volume: 118, Issue:3

    Topics: Animals; Benzoquinones; Cadherins; Cell Adhesion; Cell Adhesion Molecules; Cell Line; Cell Line, Transformed; Collagen; Fibroblasts; Fluorescent Antibody Technique; Gels; Immunoblotting; Lactams, Macrocyclic; Neoplasm Metastasis; Oncogene Protein pp60(v-src); Oncogenes; Phosphorylation; Quinones; Rats; Rifabutin; Tyrosine; Vanadates

1992
Insulin-like growth factor I rapidly induces tyrosine phosphorylation of a Mr 150,000 and a Mr 160,000 protein in highly metastatic mouse colon carcinoma 26 NL-17 cells.
    Cancer research, 1991, Nov-01, Volume: 51, Issue:21

    Topics: Animals; Antibodies, Monoclonal; Cell Line; Colonic Neoplasms; Epidermal Growth Factor; Insulin; Insulin-Like Growth Factor I; Kinetics; Mice; Molecular Weight; Neoplasm Metastasis; Neoplasm Proteins; Phosphoproteins; Phosphorylation; Phosphotyrosine; Platelet-Derived Growth Factor; Receptors, Cell Surface; Receptors, Somatomedin; Sepharose; Tyrosine

1991
Dietary restriction of tyrosine and phenylalanine: inhibition of metastasis of three rodent tumors.
    Journal of the National Cancer Institute, 1987, Volume: 78, Issue:4

    Topics: Animals; Diet; Liver Neoplasms, Experimental; Lung Neoplasms; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Neoplasm Metastasis; Neoplasm Transplantation; Neoplasms, Experimental; Phenylalanine; Tyrosine

1987
Presence and properties of tyrosinase in sera of melanoma-bearing animals.
    Acta dermato-venereologica, 1971, Volume: 51, Issue:6

    Topics: Animals; Blood; Catechol Oxidase; Centrifugation, Density Gradient; Chromatography; Cricetinae; Dihydroxyphenylalanine; Dogs; Humans; Hydrogen-Ion Concentration; Melanoma; Mice; Neoplasm Metastasis; Neoplasm Transplantation; Neoplasms, Experimental; Oxidation-Reduction; Spectrophotometry; Tissue Extracts; Tritium; Tyrosine

1971
[Alpha l-fetoprotein in liver diseases and metabolic disorders in children].
    Biomedicine / [publiee pour l'A.A.I.C.I.G.], 1973, Apr-10, Volume: 19, Issue:4

    Topics: Adolescent; Carcinoma, Hepatocellular; Child; Child, Preschool; Female; Fetal Proteins; Hepatitis; Hepatitis A; Hepatomegaly; Humans; Immunodiffusion; Infant; Infant, Newborn; Infant, Premature, Diseases; Liver Diseases; Liver Neoplasms; Male; Metabolic Diseases; Neoplasm Metastasis; Radioimmunoassay; Tyrosine

1973
[Alpha 1-fetoprotein in liver diseases and metabolic disorders in children].
    Biomedicine / [publiee pour l'A.A.I.C.I.G.], 1973, Apr-10, Volume: 19, Issue:4

    Topics: Adolescent; Carcinoma, Hepatocellular; Child; Child, Preschool; Female; Fetal Proteins; Hepatitis; Hepatitis A; Hepatomegaly; Humans; Immunodiffusion; Infant; Infant, Newborn; Infant, Premature, Diseases; Liver Diseases; Liver Neoplasms; Male; Metabolic Diseases; Neoplasm Metastasis; Radioimmunoassay; Tyrosine

1973
Reduced intake of phenylalanine and tyrosine as treatment of choroidal malignant melanoma.
    Modern problems in ophthalmology, 1974, Volume: 12, Issue:0

    Topics: Choroid Neoplasms; Dietary Proteins; Female; Humans; Melanins; Melanoma; Middle Aged; Neoplasm Metastasis; Neoplasms, Multiple Primary; Phenylalanine; Remission, Spontaneous; Tyrosine; Ultrasonics; Vision, Ocular; Visual Fields

1974
Melanocytic neoplasms.
    Clinical pharmacology and therapeutics, 1974, Volume: 16, Issue:5 Part 2

    Topics: Dihydroxyphenylalanine; Epinephrine; Humans; Melanins; Melanocytes; Melanoma; Mustard Compounds; Neoplasm Metastasis; Neurons; Phenylalanine; Pigments, Biological; Skin Neoplasms; Tyrosine

1974
The effect of a phenylalanine-tyrosine low diet on the growth and morphology of transplantable malignant melanomas of the Syrian golden hamster (Mesocricetus auratus).
    Acta pathologica et microbiologica Scandinavica. Section A, Pathology, 1973, Volume: 81, Issue:4

    Topics: Animals; Cell Transformation, Neoplastic; Copper; Cricetinae; Diet; Hair; Melanins; Melanocytes; Melanoma; Microscopy, Electron; Neoplasm Metastasis; Neoplasm Transplantation; Neoplasms, Experimental; Phenylalanine; Pigmentation Disorders; Protein Deficiency; Skin; Skin Neoplasms; Transplantation, Homologous; Tyrosine

1973
Inhibition of S-91 mouse melanoma metastases and growth by D-penicillamine.
    Laboratory investigation; a journal of technical methods and pathology, 1969, Volume: 21, Issue:5

    Topics: Animals; Catechol Oxidase; Copper; Cysteine; Melanoma; Mice; Neoplasm Metastasis; Penicillamine; Tyrosine

1969
Generalized melanosis secondary to malignant melanoma. Report of a case with serum and tissue tyrosinase studies.
    Cancer, 1969, Volume: 24, Issue:5

    Topics: Catechol Oxidase; Dihydroxyphenylalanine; Female; Humans; Lung Neoplasms; Melanins; Melanoma; Melanosis; Middle Aged; Neoplasm Metastasis; Skin Neoplasms; Splenic Neoplasms; Tyrosine; Vaginal Neoplasms

1969
Proteolytic activity of the homogenates of transplantable melanotic and amelanotic melanoma in golden hamster (Mesocricetus auratus, Waterhouse).
    Polish medical journal, 1972, Volume: 11, Issue:2

    Topics: Animals; Cricetinae; Female; Hydrogen-Ion Concentration; Melanins; Melanoma; Neoplasm Metastasis; Neoplasm Regression, Spontaneous; Neoplasm Transplantation; Neoplasms, Experimental; Nitrogen; Peptide Hydrolases; Specific Gravity; Tyrosine

1972
Failure of enzyme inhibition therapy for malignant melanoma.
    Transactions of the American Neurological Association, 1969, Volume: 94

    Topics: Adult; Brain Neoplasms; Dihydroxyphenylalanine; Dopamine; Enzyme Repression; Epinephrine; Humans; Male; Melanoma; Neoplasm Metastasis; Norepinephrine; Tyrosine

1969
Effects of reducing the phenylalanine-tyrosine intake of patients with advanced malignant melanoma.
    Cancer, 1966, Volume: 19, Issue:5

    Topics: Adult; Blood; Diet Therapy; Female; Humans; Male; Melanoma; Middle Aged; Neoplasm Metastasis; Phenylalanine; Skin Neoplasms; Tyrosine

1966