tyrosine and Necrosis

tyrosine has been researched along with Necrosis in 58 studies

Research

Studies (58)

TimeframeStudies, this research(%)All Research%
pre-19904 (6.90)18.7374
1990's4 (6.90)18.2507
2000's35 (60.34)29.6817
2010's13 (22.41)24.3611
2020's2 (3.45)2.80

Authors

AuthorsStudies
Blok, M; Harat, M; Makarewicz, K; Małkowski, B; Miechowicz, I; Wiatrowska, I1
Al Shughri, A; Brunn, A; Fink, GR; Galldiks, N; Kabbasch, C; Langen, KJ; Rosen, EK; Rueß, D; Ruge, MI; Stetter, I; Tscherpel, C; Werner, JM; Werr, L; Wollring, MM1
Choi, J; Jang, SI; Kim, SZ; Park, KH; Shin, JH1
Başaran-Küçükgergin, C; Bingül, İ; Doğru-Abbasoğlu, S; Olgaç, V; Tekkeşin, MS; Uysal, M1
Chin, MT; Liggitt, HD; Liu, Y; Weldy, CS1
Bolcaen, J; Boterberg, T; De Vos Pharm, F; Deblaere, K; Decrock, E; Descamps, B; Goethals, I; Kalala, JP; Leybaert, L; Van den Broecke, C; Vanhove, C1
Dai, Z; Diao, Y; Kang, H; Lin, S; Ma, X; Min, W; Wang, X; Zhao, Y1
Bolcaen, J; Boterberg, T; De Vos, F; Deblaere, K; Descamps, B; Goethals, I; Kalala, JP; Lybaert, K; Moerman, L; Van den Broecke, C; Vanhove, C1
Ishida, A; Ishida-Nakajima, W; Kawamura, M; Miura, S; Oguma, R; Ohmura, A; Sato, Y; Takahashi, T1
Giannitsis, E; Ivandic, BT; Katus, HA; Keck, F; Kurz, K; Lehrke, S; Staritz, P1
Doğru-Abbasoğlu, S; Giriş, M; Olgaç, V; Unlüçerçi, Y; Uysal, M; Yalçinkaya, S1
Andreotti, F; Brancati, M; Burzotta, F; Crea, F; De Vita, M; Giammarinaro, M; Leone, AM; Mazzari, MA; Niccoli, G; Porto, I; Schiavoni, G; Talarico, GP; Todaro, D; Trani, C1
Bátkai, S; Haskó, G; Kashiwaya, Y; Liaudet, L; Mukhopadhyay, P; Pacher, P; Rajesh, M; Szabó, C1
Cai, X; Fu, F; Gao, F; Ji, L; Liu, W; Zhang, H; Zhang, L; Zheng, Q1
Rehman, H; Shi, Y; Wright, GL; Zhong, Z1
Clerc, S; Feihl, F; Li, J; Liaudet, L; Loukili, N; Pacher, P; Rosenblatt-Velin, N; Waeber, B1
Candemir, B; Erol, C; Gerede, M; Kaya, CT; Kilickap, M; Kumbasar, D; Ozcan, OU; Ozdemir, AO; Ozdol, C1
Coenen, HH; Filss, CP; Fink, GR; Galldiks, N; Herzog, H; Langen, KJ; Piroth, MD; Ruge, MI; Sabel, M; Shah, NJ; Stoffels, G1
Jiang, ZA; Nanji, AA; Wang, W; Zhao, CY; Zhen, Z; Zhou, JY1
Chen, B; Cui, Y; Huang, C; Ji, L; Li, R; Ma, L; Xing, W; Yu, J; Zhang, H; Zhang, W; Zhou, H1
Fisher, EA; Kamran, M; Kini, AS; Lee, P; Marmur, JD; Perez, N; Richard, M; Sharma, SK; Suleman, J1
Farhood, A; Ho, YS; Jaeschke, H; Knight, TR1
Hirata, K; Isobe, M; Katsuramaki, T; Kimura, H; Kukita, K; Meguro, M; Nagayama, M; Nui, A1
Arteel, GE; Conzelmann, LO; Lehnert, M; Lemasters, JJ; Smutney, OM; Thurman, RG; Zhong, Z1
Boeren, S; de Wit, PJ; Francoijs, KJ; Joosten, MH; Roth, R; van den Burg, HA; Vervoort, J; Westerink, N; Woestenenk, E1
Huang, CH; Kudej, RK; Peppas, AP; Vatner, SF; Yang, G1
Britti, D; Cuzzocrea, S; Di Paola, R; Genovese, T; Mazzon, E; Serraino, I; Siriwardena, A; Thiemerman, C; Virlos, I1
Barrera, D; Cerón, A; Hernández-Pando, R; Maldonado, PD; Medina-Campos, ON; Pedraza-Chaverrí, J1
Capodici, J; Karikó, K; Lamphier, M; Ni, H; Weissman, D1
Domanovits, H; Frossard, M; Fuchs, I; Hsieh, K; Jilma, B; Laggner, AN; Leitner, JM; Losert, H; Schreiber, W; Vlcek, M1
Aguzzi, A; Buck, A; Hermann, DM; Kaser-Hotz, B; Lutz, A; Pahnke, J; Radovanovic, I; Scheidegger, S; Spaeth, N; Verwey, J; Weber, B; Weishaupt, D; Westera, G; Wild, D; Wyss, MT1
Drucker, L; Gronich, N; Lishner, M; Radnay, J; Shapiro, H; Yarkoni, S1
Bahr, BA; Blomgren, K; Hagberg, H; Shibata, M; Uchiyama, Y; Wang, X; Xu, F; Zhu, C1
Jebe, E; Petrunkina, AM; Töpfer-Petersen, E1
Cederbaum, AI; Lu, Y; Wang, X1
Heeg, MH; Koziolek, MJ; Müller, GA; Schaefer, L; Sharma, K; Strutz, F; Vasko, R1
Schilling, L; Weinzierl, N; Woitzik, J1
Badia, T; Bellandi, F; Dabizzi, RP; De Servi, S; Leoncini, M; Maioli, M; Politi, A; Toso, A1
Akkari, Y; Al-Dhalimy, M; Finegold, M; Fleming, WH; Grompe, M; Held, PK; Jiang, S; Olson, S; Torimaru, Y; Willenbring, H1
Bernardos, A; Corrales, FJ; González, R; López, P; López-Sánchez, LM; Muntané, J; Rodríguez-Ariza, A1
Cotter, TG; England, K1
Abe, A; Abe, H; Fukuda, H; Imajoh-Ohmi, S; Ishikawa, N; Kuwae, A; Matsuzawa, T; Nonaka, T1
Cheung, JY; Conrad, K; Miller, BA; Tong, Q; Wozney, J; Zhang, W1
Blom, AM; Clark, SJ; Day, AJ; Heinegård, D; Sim, RB; Sjöberg, AP; Sjölander, J; Trouw, LA1
Emiroglu, M; Gulmez, SE; Heper, AO; Kaya, B; Serel, S1
Rabinowitz, JG1
Hiai, H; Kim, BM; Nishimura, Y; Suzuki, S; Tanaka, T; Toyokuni, S; Um, SC1
Beal, MF; Dhawan, J; Disatnik, MH; Franco, AA; Rando, TA; Whirl, MM; Yu, Y1
Hoekstra, HJ; Kole, AC; Molenaar, WM; Plaat, BE; Vaalburg, W1
Ault, SG; Hinson, JA; Michael, SL; Pumford, NR1
Bauer, JA; Crouser, ED; Fahy, RJ; Julian, MW; Weinstein, DM1
Brown, PA; Chatterjee, PK; Cuzzocrea, S; Mota-Filipe, H; Stewart, KN; Thiemermann, C; Zacharowski, K1
Bai, P; Bakondi, E; Gergely, P; Gyüre, L; Haskó, G; Hunyadi, J; Szabó, C; Szabó, E; Virág, L1
Ehring, GR; Jones, MK; Kawanaka, H; Pai, R; Szabó, IL; Tarnawski, AS1
McKenzie, B; Stabback, S; Yeo, JD1
Arteaga, CL; Awad, JA; Boland, CR; Coffey, RJ; Kraus, ER; Nanney, LB; Polk, WH; Romano, M; Wargovich, MJ1
Bernsmeier, H; Lenz, W; Sons, HU; Weber, U1
Samofalova, MS1

Reviews

1 review(s) available for tyrosine and Necrosis

ArticleYear
Direct oxidative modifications of signalling proteins in mammalian cells and their effects on apoptosis.
    Redox report : communications in free radical research, 2005, Volume: 10, Issue:5

    Topics: Antioxidants; Apoptosis; Endoplasmic Reticulum; Humans; Mitochondria; Models, Biological; Necrosis; Oxidation-Reduction; Oxidative Stress; Oxygen; Reactive Nitrogen Species; Reactive Oxygen Species; Signal Transduction; Tyrosine

2005

Trials

5 trial(s) available for tyrosine and Necrosis

ArticleYear
Tirofiban optimizes platelet inhibition for immediate percutaneous coronary intervention in high-risk acute coronary syndromes.
    Thrombosis and haemostasis, 2008, Volume: 100, Issue:4

    Topics: Aged; Angioplasty, Balloon, Coronary; Aspirin; Blood Platelets; Clopidogrel; Coronary Artery Disease; Coronary Thrombosis; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Myocardial Infarction; Necrosis; Platelet Aggregation Inhibitors; Risk Factors; Ticlopidine; Tirofiban; Treatment Outcome; Tyrosine

2008
Glycoprotein IIB/IIIA inhibitor to reduce postpercutaneous coronary intervention myonecrosis and improve coronary flow in diabetics: the 'OPTIMIZE-IT' pilot randomized study.
    Journal of cardiovascular medicine (Hagerstown, Md.), 2009, Volume: 10, Issue:3

    Topics: Aged; Angioplasty, Balloon, Coronary; Biomarkers; Cardiovascular Diseases; Coronary Angiography; Coronary Artery Disease; Coronary Circulation; Diabetes Complications; Drug Therapy, Combination; Female; Fibrinolytic Agents; Humans; Male; Middle Aged; Myocardium; Necrosis; Pilot Projects; Platelet Aggregation; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Prospective Studies; Stents; Time Factors; Tirofiban; Treatment Outcome; Troponin T; Tyrosine

2009
Intracoronary versus intravenous high-dose bolus plus maintenance administration of tirofiban in patients undergoing primary percutaneous coronary intervention for acute ST elevation myocardial infarction.
    Journal of thrombosis and thrombolysis, 2012, Volume: 34, Issue:1

    Topics: Aged; Angioplasty, Balloon, Coronary; Blood Flow Velocity; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Myocardial Infarction; Necrosis; Pilot Projects; Platelet Aggregation Inhibitors; Time Factors; Tirofiban; Tyrosine

2012
Effectiveness of tirofiban, eptifibatide, and abciximab in minimizing myocardial necrosis during percutaneous coronary intervention (TEAM pilot study).
    The American journal of cardiology, 2002, Sep-01, Volume: 90, Issue:5

    Topics: Abciximab; Aged; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Cardiac Catheterization; Cardiomyopathies; Combined Modality Therapy; Creatine Kinase; Creatine Kinase, MB Form; Eptifibatide; Female; Humans; Immunoglobulin Fab Fragments; Incidence; Isoenzymes; Male; Middle Aged; Myocardial Infarction; Necrosis; Peptides; Pilot Projects; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Predictive Value of Tests; Stroke Volume; Tirofiban; Treatment Outcome; Troponin I; Tyrosine

2002
Effects of tirofiban plus clopidogrel versus clopidogrel plus provisional abciximab on biomarkers of myocardial necrosis in patients with non-ST-elevation acute coronary syndromes treated with early aggressive approach. Results of the CLOpidogrel, upstrea
    American heart journal, 2005, Volume: 150, Issue:3

    Topics: Abciximab; Acute Disease; Aged; Angina, Unstable; Antibodies, Monoclonal; Clopidogrel; Creatine Kinase, MB Form; Electrocardiography; Female; Humans; Immunoglobulin Fab Fragments; Male; Myocardial Infarction; Necrosis; Prospective Studies; Syndrome; Ticlopidine; Time Factors; Tirofiban; Troponin I; Tyrosine

2005

Other Studies

52 other study(ies) available for tyrosine and Necrosis

ArticleYear
Safety and Efficacy of Irradiation Boost Based on 18F-FET-PET in Patients with Newly Diagnosed Glioblastoma.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2022, 07-15, Volume: 28, Issue:14

    Topics: Brain Neoplasms; Glioblastoma; Humans; Necrosis; Pilot Projects; Positron-Emission Tomography; Prospective Studies; Tyrosine

2022
Multimodal imaging findings in patients with glioblastoma with extensive coagulative necrosis related to regorafenib.
    Neuro-oncology, 2023, 06-02, Volume: 25, Issue:6

    Topics: Brain Neoplasms; Glioblastoma; Glioma; Humans; Magnetic Resonance Imaging; Multimodal Imaging; Necrosis; Positron-Emission Tomography; Tyrosine

2023
The ameliorative effects of L-2-oxothiazolidine-4-carboxylate on acetaminophen-induced hepatotoxicity in mice.
    Molecules (Basel, Switzerland), 2013, Mar-18, Volume: 18, Issue:3

    Topics: Acetaminophen; Alanine Transaminase; Aldehydes; Analgesics, Non-Narcotic; Animals; Antioxidants; Apoptosis; Aspartate Aminotransferases; Caspase 3; Chemical and Drug Induced Liver Injury; DNA Fragmentation; Glutathione; Glutathione Peroxidase; Liver; Male; Malondialdehyde; Mice; Mice, Inbred BALB C; Necrosis; Oxidative Stress; Pyrrolidonecarboxylic Acid; Thiazolidines; Tyrosine

2013
Effect of blueberry pretreatment on diethylnitrosamine-induced oxidative stress and liver injury in rats.
    Environmental toxicology and pharmacology, 2013, Volume: 36, Issue:2

    Topics: Animals; Antioxidants; Apoptosis; Biomarkers; Blueberry Plants; Cell Proliferation; Chemical and Drug Induced Liver Injury; Diethylnitrosamine; Disease Models, Animal; Drug Administration Schedule; Fruit; Glutathione; Glutathione Peroxidase; Glutathione Transferase; Liver; Male; Necrosis; Oxidative Stress; Phytotherapy; Plant Extracts; Plants, Medicinal; Protein Carbonylation; Rats; Rats, Wistar; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Time Factors; Tyrosine

2013
In utero exposure to diesel exhaust air pollution promotes adverse intrauterine conditions, resulting in weight gain, altered blood pressure, and increased susceptibility to heart failure in adult mice.
    PloS one, 2014, Volume: 9, Issue:2

    Topics: Air Pollutants; Animals; Aorta; Blood Pressure; Echocardiography; Female; Heart Failure; Inflammation; Inhalation Exposure; Leukocyte Common Antigens; Male; Maternal Exposure; Mice; Mice, Inbred C57BL; Myocardium; Necrosis; Oxidative Stress; Particle Size; Pregnancy; Pregnancy, Animal; Time Factors; Tyrosine; Vehicle Emissions; Weight Gain

2014
(18)F-fluoromethylcholine (FCho), (18)F-fluoroethyltyrosine (FET), and (18)F-fluorodeoxyglucose (FDG) for the discrimination between high-grade glioma and radiation necrosis in rats: a PET study.
    Nuclear medicine and biology, 2015, Volume: 42, Issue:1

    Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Choline; Diagnosis, Differential; Female; Fluorodeoxyglucose F18; Glioblastoma; Necrosis; Neoplasm Grading; Positron-Emission Tomography; Radiation Injuries; Radioactive Tracers; Radiopharmaceuticals; Rats; Recurrence; Tyrosine

2015
Dasatinib promotes paclitaxel-induced necroptosis in lung adenocarcinoma with phosphorylated caspase-8 by c-Src.
    Cancer letters, 2016, 08-28, Volume: 379, Issue:1

    Topics: A549 Cells; Adenocarcinoma; Adenocarcinoma of Lung; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Caspase 8; Cisplatin; Dasatinib; Disease-Free Survival; Drug Resistance, Neoplasm; Female; Humans; Kaplan-Meier Estimate; Lung Neoplasms; Male; Mice, Inbred BALB C; Mice, Nude; Middle Aged; Necrosis; Paclitaxel; Phosphorylation; Pregnancy; Protein Kinase Inhibitors; Proto-Oncogene Proteins pp60(c-src); Receptor-Interacting Protein Serine-Threonine Kinases; RNA Interference; Signal Transduction; Time Factors; Transfection; Treatment Outcome; Tyrosine; Xenograft Model Antitumor Assays

2016
Kinetic Modeling and Graphical Analysis of 18F-Fluoromethylcholine (FCho), 18F-Fluoroethyltyrosine (FET) and 18F-Fluorodeoxyglucose (FDG) PET for the Fiscrimination between High-Grade Glioma and Radiation Necrosis in Rats.
    PloS one, 2016, Volume: 11, Issue:8

    Topics: Animals; Brain; Cell Line, Tumor; Choline; Diagnosis, Differential; Disease Models, Animal; Female; Fluorodeoxyglucose F18; Glioblastoma; Humans; Kinetics; Necrosis; Neoplasm Grading; Positron-Emission Tomography; Radiation Injuries; Radiopharmaceuticals; Rats, Inbred F344; Reproducibility of Results; Sensitivity and Specificity; Tyrosine

2016
Ascorbic acid protects the newborn rat brain from hypoxic-ischemia.
    Brain & development, 2009, Volume: 31, Issue:4

    Topics: Analysis of Variance; Animals; Animals, Newborn; Antioxidants; Apoptosis; Ascorbic Acid; Blotting, Western; Brain; Brain Ischemia; Calpain; Carrier Proteins; Caspase 3; Enzyme Activation; In Situ Nick-End Labeling; Microfilament Proteins; Microscopy, Electron; Necrosis; Neurons; Neuroprotective Agents; Rats; Tyrosine

2009
Oxidative and nitrosative stress and apoptosis in the liver of rats fed on high methionine diet: protective effect of taurine.
    Nutrition (Burbank, Los Angeles County, Calif.), 2009, Volume: 25, Issue:4

    Topics: Alanine Transaminase; Animals; Antioxidants; Apoptosis; Aspartate Aminotransferases; bcl-2-Associated X Protein; Hyperhomocysteinemia; Inflammation; Lipid Peroxides; Liver; Male; Malondialdehyde; Methionine; Necrosis; Nitrosation; Oxidative Stress; Rats; Rats, Wistar; Taurine; Tyrosine

2009
Role of superoxide, nitric oxide, and peroxynitrite in doxorubicin-induced cell death in vivo and in vitro.
    American journal of physiology. Heart and circulatory physiology, 2009, Volume: 296, Issue:5

    Topics: Animals; Antibiotics, Antineoplastic; Antioxidants; Apoptosis; Cell Line; Dose-Response Relationship, Drug; Doxorubicin; Enzyme Inhibitors; Free Radical Scavengers; Heart Diseases; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitochondria, Heart; Myocardial Contraction; Myocytes, Cardiac; Necrosis; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type II; Peroxynitrous Acid; Poly(ADP-ribose) Polymerases; Superoxides; Tyrosine; Ventricular Function, Left; Ventricular Pressure

2009
Insulin attenuates myocardial ischemia/reperfusion injury via reducing oxidative/nitrative stress.
    American journal of physiology. Endocrinology and metabolism, 2010, Volume: 298, Issue:4

    Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Caspase 3; Creatine Kinase; Electrocardiography; Heart Function Tests; Hypoglycemic Agents; In Situ Nick-End Labeling; Insulin; L-Lactate Dehydrogenase; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Necrosis; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reactive Nitrogen Species; Reperfusion Injury; Tyrosine

2010
Inhibition of inducible nitric oxide synthase prevents graft injury after transplantation of livers from rats after cardiac death.
    Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 2010, Volume: 16, Issue:11

    Topics: Alanine Transaminase; Animals; Bilirubin; Death; Enzyme Inhibitors; Graft Rejection; Graft Survival; Imines; Liver; Liver Transplantation; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinase 9; Necrosis; Nitrates; Nitric Oxide Synthase Type II; Nitrites; Peroxynitrous Acid; Rats; Rats, Inbred Lew; Reactive Nitrogen Species; Tyrosine

2010
Peroxynitrite induces HMGB1 release by cardiac cells in vitro and HMGB1 upregulation in the infarcted myocardium in vivo.
    Cardiovascular research, 2011, Feb-15, Volume: 89, Issue:3

    Topics: Animals; Apoptosis; Cells, Cultured; HMGB1 Protein; Male; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinases; Myoblasts, Cardiac; Myocardial Infarction; Necrosis; Peroxynitrous Acid; Rats; Rats, Wistar; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Toll-Like Receptor 4; Tyrosine; Up-Regulation

2011
Role of O-(2-(18)F-fluoroethyl)-L-tyrosine PET for differentiation of local recurrent brain metastasis from radiation necrosis.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2012, Volume: 53, Issue:9

    Topics: Adolescent; Adult; Aged; Biological Transport; Brain Neoplasms; Diagnosis, Differential; Humans; Male; Middle Aged; Necrosis; Neoplasm Recurrence, Local; Positron-Emission Tomography; Radiation Injuries; ROC Curve; Tyrosine; Young Adult

2012
Long-term binge and escalating ethanol exposure causes necroinflammation and fibrosis in rat liver.
    Alcoholism, clinical and experimental research, 2013, Volume: 37, Issue:2

    Topics: Animals; Binge Drinking; Cyclooxygenase 1; Cyclooxygenase 2; Cytokines; Ethanol; Hypoxia-Inducible Factor 1; Inflammation; Inflammation Mediators; Liver; Liver Cirrhosis; Male; Necrosis; Nitric Oxide Synthase Type II; Oxidative Stress; Procollagen; Rats; Rats, Wistar; Tyrosine

2013
Catalpol decreases peroxynitrite formation and consequently exerts cardioprotective effects against ischemia/reperfusion insult.
    Pharmaceutical biology, 2013, Volume: 51, Issue:4

    Topics: Animals; Antioxidants; Apoptosis; Cardiotonic Agents; Disease Models, Animal; Down-Regulation; Enzyme Activation; Free Radical Scavengers; Injections, Intraperitoneal; Iridoid Glucosides; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Necrosis; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxidative Stress; Peroxynitrous Acid; Phosphatidylinositol 3-Kinase; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Time Factors; Tyrosine

2013
Peroxynitrite is a critical mediator of acetaminophen hepatotoxicity in murine livers: protection by glutathione.
    The Journal of pharmacology and experimental therapeutics, 2002, Volume: 303, Issue:2

    Topics: Acetaminophen; Alanine Transaminase; Analgesics, Non-Narcotic; Animals; Antidotes; Chemical and Drug Induced Liver Injury; Glutathione; Immunohistochemistry; Injections, Intravenous; Liver; Male; Mice; Mice, Inbred C3H; Mitochondria, Liver; Necrosis; Peroxynitrous Acid; Serum Albumin, Bovine; Tyrosine

2002
Apoptosis and necrosis after warm ischemia-reperfusion injury of the pig liver and their inhibition by ONO-1714.
    Transplantation, 2003, Mar-15, Volume: 75, Issue:5

    Topics: Amidines; Animals; Apoptosis; Aspartate Aminotransferases; DNA; Enzyme Inhibitors; Female; Hepatocytes; Heterocyclic Compounds, 2-Ring; Hot Temperature; In Situ Nick-End Labeling; Ischemia; L-Lactate Dehydrogenase; Liver; Liver Circulation; Microscopy, Confocal; Microscopy, Electron; Necrosis; Nitrates; Nitric Oxide Synthase; Nitrites; Reperfusion Injury; Swine; Time Factors; Tyrosine

2003
Dependence of liver injury after hemorrhage/resuscitation in mice on NADPH oxidase-derived superoxide.
    Shock (Augusta, Ga.), 2003, Volume: 19, Issue:4

    Topics: Alanine Transaminase; Animals; Chemotaxis, Leukocyte; Ischemia; Lipid Peroxidation; Liver; Mice; Mice, Inbred C57BL; Mice, Knockout; NADPH Oxidases; Necrosis; Neutrophils; Oxidative Stress; Peroxynitrous Acid; Phosphoproteins; Reperfusion Injury; Resuscitation; Shock, Hemorrhagic; Superoxides; Tyrosine

2003
Natural disulfide bond-disrupted mutants of AVR4 of the tomato pathogen Cladosporium fulvum are sensitive to proteolysis, circumvent Cf-4-mediated resistance, but retain their chitin binding ability.
    The Journal of biological chemistry, 2003, Jul-25, Volume: 278, Issue:30

    Topics: Alanine; Amino Acids; Blood Proteins; Carrier Proteins; Chitin; Chromatography, High Pressure Liquid; Cladosporium; Cysteine; Disulfides; Fungal Proteins; Genotype; Magnetic Resonance Spectroscopy; Models, Molecular; Mutation; Necrosis; Peptides; Phenotype; Polysaccharides; Protein Binding; Protein Conformation; Protein Isoforms; Protein Structure, Tertiary; Solanum lycopersicum; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Time Factors; Transcription, Genetic; Tyrosine

2003
Cardiac nerves affect myocardial stunning through reactive oxygen and nitric oxide mechanisms.
    Circulation research, 2003, Oct-31, Volume: 93, Issue:9

    Topics: Animals; Coronary Stenosis; Denervation; Enzyme Inhibitors; Heart; Hemodynamics; Immunohistochemistry; Models, Animal; Myocardial Reperfusion; Myocardial Stunning; Myocardium; Necrosis; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Norepinephrine; Reactive Oxygen Species; Swine; Tyrosine

2003
Pyrrolidine dithiocarbamate reduces the severity of cerulein-induced murine acute pancreatitis.
    Shock (Augusta, Ga.), 2003, Volume: 20, Issue:6

    Topics: Amylases; Animals; Antioxidants; Blotting, Western; Ceruletide; Edema; I-kappa B Proteins; Immunohistochemistry; Inflammation; Intercellular Adhesion Molecule-1; Lipase; Lipid Peroxidation; Male; Mice; Necrosis; Neutrophils; NF-kappa B; NF-KappaB Inhibitor alpha; Pancreatitis; Peroxidase; Pyrrolidines; Rats; Thiocarbamates; Tyrosine; Up-Regulation

2003
Protective effect of diallyl sulfide on oxidative stress and nephrotoxicity induced by gentamicin in rats.
    Molecular and cellular biochemistry, 2003, Volume: 254, Issue:1-2

    Topics: Acetylglucosaminidase; Allyl Compounds; Animals; Anti-Bacterial Agents; Antioxidants; Blood Urea Nitrogen; Body Weight; Carbon; Creatinine; Gentamicins; Immunohistochemistry; Kidney; Kidney Cortex; Kidney Tubules; Male; Necrosis; Olive Oil; Oxidative Stress; Oxygen; Plant Oils; Rats; Rats, Wistar; Reactive Oxygen Species; Sulfides; Time Factors; Tyrosine

2003
mRNA is an endogenous ligand for Toll-like receptor 3.
    The Journal of biological chemistry, 2004, Mar-26, Volume: 279, Issue:13

    Topics: Blotting, Northern; Cell Line; Dendritic Cells; Dose-Response Relationship, Drug; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Genistein; Humans; Interleukin-1 Receptor-Associated Kinases; Interleukin-8; Ligands; Luciferases; Membrane Glycoproteins; Necrosis; NF-kappa B; Nucleic Acid Conformation; Plasmids; Protein Kinases; Receptors, Cell Surface; RNA; RNA, Double-Stranded; RNA, Messenger; Signal Transduction; Staurosporine; Toll-Like Receptor 3; Toll-Like Receptors; Transcription, Genetic; Transfection; Tumor Necrosis Factor-alpha; Tyrosine; Up-Regulation

2004
Platelet function predicts myocardial damage in patients with acute myocardial infarction.
    Circulation, 2004, Sep-14, Volume: 110, Issue:11

    Topics: Abciximab; Adenosine Diphosphate; Aged; Antibodies, Monoclonal; Anticoagulants; Aspirin; Cardiovascular Agents; Clopidogrel; Collagen; Comorbidity; Eptifibatide; Female; Humans; Immunoglobulin Fab Fragments; Leukocyte Count; Male; Middle Aged; Myocardial Infarction; Myocardial Ischemia; Myocardium; Necrosis; Peptides; Platelet Activation; Platelet Aggregation Inhibitors; Platelet Function Tests; Predictive Value of Tests; Prospective Studies; Ticlopidine; Tirofiban; Tyrosine; von Willebrand Factor

2004
Uptake of 18F-fluorocholine, 18F-fluoroethyl-L-tyrosine, and 18F-FDG in acute cerebral radiation injury in the rat: implications for separation of radiation necrosis from tumor recurrence.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2004, Volume: 45, Issue:11

    Topics: Acute Disease; Animals; Brain; Brain Injuries; Brain Neoplasms; Fluorine Radioisotopes; Fluorodeoxyglucose F18; Male; Necrosis; Neoplasm Recurrence, Local; Quaternary Ammonium Compounds; Radiation Injuries, Experimental; Radionuclide Imaging; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Tyrosine

2004
Simvastatin induces death of multiple myeloma cell lines.
    Journal of investigative medicine : the official publication of the American Federation for Clinical Research, 2004, Volume: 52, Issue:5

    Topics: Anticholesteremic Agents; Antineoplastic Agents; Apoptosis; Calcium; Cell Cycle; Cell Death; Cell Line, Tumor; Humans; Interleukin-6; Multiple Myeloma; Necrosis; Phosphorylation; Simvastatin; Tyrosine

2004
The influence of age on apoptotic and other mechanisms of cell death after cerebral hypoxia-ischemia.
    Cell death and differentiation, 2005, Volume: 12, Issue:2

    Topics: Aging; Animals; Apoptosis; Apoptosis Inducing Factor; Autophagy; Brain Injuries; Calpain; Caspase 3; Caspases; Cell Death; Cytochromes c; Disease Models, Animal; Flavoproteins; Hypoxia-Ischemia, Brain; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Microtubule-Associated Proteins; Mitochondria; Necrosis; Neurons; Protein Transport; Tyrosine

2005
Regulatory and necrotic volume increase in boar spermatozoa.
    Journal of cellular physiology, 2005, Volume: 204, Issue:2

    Topics: Animals; Annexin A5; Cell Size; Chloride Channels; Enzyme Inhibitors; Hypertonic Solutions; Male; Necrosis; Phenols; Phosphoprotein Phosphatases; Phosphorylation; Protein-Tyrosine Kinases; Quinidine; Semen Preservation; Spermatozoa; Staining and Labeling; Staurosporine; Swine; Tamoxifen; Tyrosine; Vanadates

2005
Lipopolysaccharide-induced liver injury in rats treated with the CYP2E1 inducer pyrazole.
    American journal of physiology. Gastrointestinal and liver physiology, 2005, Volume: 289, Issue:2

    Topics: Animals; Apoptosis; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP2E1; Drug Synergism; Enzyme Inhibitors; Lipid Peroxidation; Lipopolysaccharides; Liver; Male; Necrosis; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxidative Stress; Proteins; Pyrazoles; Rats; Rats, Sprague-Dawley; Superoxides; Tyrosine

2005
The antifibrotic effects of relaxin in human renal fibroblasts are mediated in part by inhibition of the Smad2 pathway.
    Kidney international, 2005, Volume: 68, Issue:1

    Topics: Apoptosis; Cell Division; Cell Line; DNA-Binding Proteins; Extracellular Matrix; Fibroblasts; Fibrosis; Humans; Kidney; MAP Kinase Signaling System; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Necrosis; Phosphorylation; Receptors, Transforming Growth Factor beta; Relaxin; Smad2 Protein; Smad3 Protein; Trans-Activators; Transforming Growth Factor beta; Transforming Growth Factor beta1; Tyrosine

2005
Early administration of a second-generation perfluorochemical decreases ischemic brain damage in a model of permanent middle cerebral artery occlusion in the rat.
    Neurological research, 2005, Volume: 27, Issue:5

    Topics: Analysis of Variance; Animals; Blood Gas Analysis; Brain Ischemia; Cerebrovascular Circulation; Disease Models, Animal; Drug Therapy, Combination; Fluorocarbons; Immunohistochemistry; Infarction, Middle Cerebral Artery; Laser-Doppler Flowmetry; Male; Necrosis; Neuroprotective Agents; Oxygen; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley; Silver Staining; Time Factors; Tyrosine

2005
In vivo genetic selection of renal proximal tubules.
    Molecular therapy : the journal of the American Society of Gene Therapy, 2006, Volume: 13, Issue:1

    Topics: Acute Disease; Animals; Bone Marrow Transplantation; Cell Differentiation; Cell Fusion; Chronic Disease; Disease Models, Animal; Homogentisate 1,2-Dioxygenase; Homogentisic Acid; Hydrolases; Kidney Diseases; Kidney Tubules, Proximal; Male; Mice; Mice, Knockout; Necrosis; Regeneration; Tyrosine; Urothelium

2006
Altered protein expression and protein nitration pattern during d-galactosamine-induced cell death in human hepatocytes: a proteomic analysis.
    Liver international : official journal of the International Association for the Study of the Liver, 2005, Volume: 25, Issue:6

    Topics: Apoptosis; Cell Death; Cells, Cultured; Galactosamine; Hepatocytes; Humans; Necrosis; Nitrates; Oxidative Stress; Proteins; Proteomics; Tyrosine

2005
BopC is a novel type III effector secreted by Bordetella bronchiseptica and has a critical role in type III-dependent necrotic cell death.
    The Journal of biological chemistry, 2006, Mar-10, Volume: 281, Issue:10

    Topics: Animals; Bacterial Proteins; Bordetella bronchiseptica; Bordetella Infections; Cell Line; Chlorocebus aethiops; COS Cells; HeLa Cells; Humans; Necrosis; Phosphorylation; Tyrosine

2006
Regulation of TRP channel TRPM2 by the tyrosine phosphatase PTPL1.
    American journal of physiology. Cell physiology, 2007, Volume: 292, Issue:5

    Topics: Apoptosis; Calcium Signaling; Cell Survival; Genistein; Humans; Hydrogen Peroxide; Immunoprecipitation; Necrosis; Oxidative Stress; Phosphorylation; Protein Binding; Protein Interaction Mapping; Protein Kinase Inhibitors; Protein Tyrosine Phosphatase, Non-Receptor Type 13; Protein Tyrosine Phosphatases; Pyrimidines; RNA Interference; RNA, Small Interfering; Time Factors; Transfection; TRPM Cation Channels; Tumor Necrosis Factor-alpha; Tyrosine; U937 Cells

2007
The factor H variant associated with age-related macular degeneration (His-384) and the non-disease-associated form bind differentially to C-reactive protein, fibromodulin, DNA, and necrotic cells.
    The Journal of biological chemistry, 2007, Apr-13, Volume: 282, Issue:15

    Topics: Alternative Splicing; C-Reactive Protein; Cell Line; Complement Factor H; DNA; Extracellular Matrix Proteins; Fibromodulin; Histidine; Humans; Macular Degeneration; Necrosis; Protein Binding; Proteoglycans; Surface Plasmon Resonance; Tyrosine

2007
Effect of platelet glycoprotein IIb/IIIa receptor antagonist on survival of epigastric island flaps in rats with total venous occlusions.
    Scandinavian journal of plastic and reconstructive surgery and hand surgery, 2008, Volume: 42, Issue:1

    Topics: Abdominal Wall; Animals; Disease Models, Animal; Graft Survival; Laser-Doppler Flowmetry; Male; Necrosis; Platelet Aggregation Inhibitors; Rats; Rats, Wistar; Surgical Flaps; Tirofiban; Tyrosine; Venous Insufficiency

2008
Abnormalities of the liver and other organs.
    Radiologic clinics of North America, 1980, Volume: 18, Issue:2

    Topics: Abnormalities, Multiple; alpha 1-Antitrypsin Deficiency; Amino Acid Metabolism, Inborn Errors; Colitis; Colon; Cystinosis; Heart Failure; Hemochromatosis; Hepatolenticular Degeneration; Humans; Liver; Liver Diseases; Necrosis; Radiography; Sclerosis; Tyrosine

1980
Involvement of nitric oxide in survival of random pattern skin flap.
    Plastic and reconstructive surgery, 1998, Volume: 101, Issue:3

    Topics: Animals; Arginine; Blotting, Western; Endothelium, Vascular; Enzyme Inhibitors; Free Radicals; Graft Survival; Injections, Intraperitoneal; Ischemia; Laser-Doppler Flowmetry; Male; Microcirculation; Necrosis; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Oxidation-Reduction; Rats; Rats, Wistar; Regional Blood Flow; Skin; Skin Transplantation; Tyrosine

1998
Evidence of oxidative stress in mdx mouse muscle: studies of the pre-necrotic state.
    Journal of the neurological sciences, 1998, Nov-26, Volume: 161, Issue:1

    Topics: Animals; Gene Expression; Mice; Mice, Inbred C57BL; Mice, Inbred mdx; Muscles; Necrosis; Nitric Oxide; Oxidative Stress; Oxidoreductases; Reference Values; Tyrosine

1998
FDG and L-[1-11C]-tyrosine imaging of soft-tissue tumors before and after therapy.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1999, Volume: 40, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Carbon Radioisotopes; Cell Division; Female; Fluorodeoxyglucose F18; Humans; Male; Middle Aged; Mitosis; Necrosis; Radiopharmaceuticals; Soft Tissue Neoplasms; Tomography, Emission-Computed; Tyrosine

1999
Western blot analysis for nitrotyrosine protein adducts in livers of saline-treated and acetaminophen-treated mice.
    Toxicological sciences : an official journal of the Society of Toxicology, 2000, Volume: 53, Issue:2

    Topics: Acetaminophen; Adjuvants, Immunologic; Analgesics, Non-Narcotic; Animals; Blotting, Western; Cattle; Chemical and Drug Induced Liver Injury; Enzyme-Linked Immunosorbent Assay; Hemocyanins; Immunoenzyme Techniques; Liver; Male; Mice; Mice, Inbred C57BL; Necrosis; Nitrates; Protein Binding; Proteins; Rabbits; Serum Albumin, Bovine; Sodium Chloride; Tyrosine

2000
Endotoxin-induced ileal mucosal injury and nitric oxide dysregulation are temporally dissociated.
    American journal of respiratory and critical care medicine, 2000, Volume: 161, Issue:5

    Topics: Animals; Apoptosis; Cats; Ileum; Immunohistochemistry; Intestinal Mucosa; Lipopolysaccharides; Male; Mitochondria; Multiple Organ Failure; Necrosis; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxygen Consumption; Sepsis; Tyrosine

2000
Tempol, a membrane-permeable radical scavenger, reduces oxidant stress-mediated renal dysfunction and injury in the rat.
    Kidney international, 2000, Volume: 58, Issue:2

    Topics: Acute Kidney Injury; Animals; Cell Membrane Permeability; Cell Separation; Cells, Cultured; Chelating Agents; Cyclic N-Oxides; Deferoxamine; Disease Models, Animal; Free Radical Scavengers; Hydrogen Peroxide; Kidney Glomerulus; Kidney Tubules, Proximal; Male; Malondialdehyde; Necrosis; Oxidants; Oxidative Stress; Peroxidase; Poly(ADP-ribose) Polymerases; Rats; Rats, Wistar; Reperfusion Injury; Spin Labels; Tyrosine

2000
Peroxynitrite production, DNA breakage, and poly(ADP-ribose) polymerase activation in a mouse model of oxazolone-induced contact hypersensitivity.
    The Journal of investigative dermatology, 2001, Volume: 117, Issue:1

    Topics: Adjuvants, Immunologic; Animals; Apoptosis; Caspases; Cell Division; Cell Line; Dermatitis, Contact; DNA Damage; DNA Fragmentation; Female; In Situ Nick-End Labeling; Intercellular Adhesion Molecule-1; Interleukin-8; Keratinocytes; Mice; Mice, Inbred Strains; Necrosis; Nitrates; Oxazolone; Poly(ADP-ribose) Polymerases; Skin; Tyrosine

2001
Indomethacin delays gastric restitution: association with the inhibition of focal adhesion kinase and tensin phosphorylation and reduced actin stress fibers.
    Experimental biology and medicine (Maywood, N.J.), 2002, Volume: 227, Issue:6

    Topics: Actins; Animals; Apoptosis; Caspase 3; Caspases; Cell Death; Cell Line; Cell Movement; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Epidermal Growth Factor; Epithelial Cells; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Gastric Mucosa; Humans; Immunoblotting; Immunohistochemistry; In Situ Nick-End Labeling; Indomethacin; Male; Microfilament Proteins; Mitomycin; Necrosis; Phosphorylation; Precipitin Tests; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Stomach; Stress Fibers; Tensins; Time Factors; Tyrosine

2002
Central necrosis following contusion to the sheep's spinal cord.
    Paraplegia, 1977, Volume: 14, Issue:4

    Topics: Animals; Contusions; Demyelinating Diseases; Hyperbaric Oxygenation; Injections, Spinal; Methylprednisolone; Movement; Necrosis; Sheep; Spinal Cord; Spinal Cord Injuries; Tyrosine

1977
Transforming growth factor alpha protection against drug-induced injury to the rat gastric mucosa in vivo.
    The Journal of clinical investigation, 1992, Volume: 90, Issue:6

    Topics: Animals; Aspirin; Dinoprostone; Ethanol; Ethylmaleimide; Gastric Mucins; Gastric Mucosa; Image Processing, Computer-Assisted; Indomethacin; Microscopy, Electron, Scanning; Necrosis; Ornithine Decarboxylase; Phosphorylation; Phosphotyrosine; Rats; Rats, Sprague-Dawley; Sulfhydryl Compounds; Time Factors; Transforming Growth Factor alpha; Type C Phospholipases; Tyrosine

1992
[Experimental tyrosine keratopathy in rabbits].
    Klinische Monatsblatter fur Augenheilkunde, 1986, Volume: 188, Issue:6

    Topics: Administration, Oral; Animals; Cornea; Corneal Opacity; Endothelium; Epithelium; Keratitis, Dendritic; Male; Microscopy, Electron, Scanning; Necrosis; Rabbits; Tyrosine

1986
[Levels of free amino acids in the blood and heart muscle in the human at various periods of myocardial infarct (clinical anatomical parallels)].
    Kardiologiia, 1968, Volume: 8, Issue:11

    Topics: Alanine; Amino Acids; Arginine; Aspartic Acid; Chromatography; Erythrocytes; Glutamates; Glycine; Histidine; Histocytochemistry; Humans; Isoleucine; Leucine; Lysine; Methods; Middle Aged; Myocardial Infarction; Myocardium; Necrosis; Phenylalanine; Serine; Threonine; Time Factors; Tyrosine; Valine

1968
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