Compounds > tyrosine

tyrosine and Injury, Myocardial Reperfusion

tyrosine has been researched along with Injury, Myocardial Reperfusion in 93 studies

Research

Studies (93)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (1.08)18.2507
2000's49 (52.69)29.6817
2010's43 (46.24)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Andreadou, I; Bibli, SI; Brouckaert, P; Fisslthaler, B; Fleming, I; Papapetropoulos, A; Szabo, C; Zhou, Z; Zukunft, S1
An, Y; Guo, JJ; Hu, LG; Li, J; Li, YH; Liu, X; Wang, XF; Xu, FQ1
Garry, M; Groehler, A; Kren, S; Li, Q; Robledo-Villafane, M; Schmidt, J; Tretyakova, N1
Chang, ST; Chu, CM; Chung, CM; Hsiao, JF; Hsu, JT; Lin, YS; Pan, KL; Yang, YT1
Huhn, R; Mayer, F; Ritz-Timme, S; Scholl, K1
Chen, Q; Deng, R; Gao, Z; Li, Z; Liu, Q; Liu, Y; Peng, X; Xiao, Q; Yu, F; Zhang, Y1
Kaplan, P; Kovalska, M; Lehotsky, J; Racay, P; Sivonova, MK; Tatarkova, Z1
Abad, E; Garcia-Dorado, D; Hernando, V; Inserte, J; Poncelas-Nozal, M; Vilardosa, Ú1
Liu, J; Lloyd, SG1
Csonka, C; Csont, T; Ferdinandy, P; Görbe, A; Kocsis, GF; Murlasits, Z; Pálóczi, J; Szűcs, G; Török, S1
Abd El Motteleb, DM; Elshazly, SM; Nassar, NN1
Hagiri, S; Hataishi, R; Hirose, M; Kobayashi, H; Kokubo, K; Sato, Y; Shinbo, T1
Feihl, F; Li, J; Liaudet, L; Loukili, N; Pacher, P; Rosenblatt-Velin, N; Waeber, B1
Chen, C; Cheung, CW; Irwin, MG; Li, H; Liu, Z; Wang, J; Wong, GT; Xia, Z; Zhang, L1
Andreadou, I; Benaki, D; Bibli, SI; Efentakis, P; Iliodromitis, EK; Mikros, E; Milioni, AI; Papachristodoulou, A; Skaltsounis, AL; Zoga, A1
Gönczi, M; Kaszaki, J; Kiss, A; Kohr, MJ; Kovács, M; Miskolczi, G; Murphy, E; Seprényi, G; Végh, Á1
Chang, ST; Chu, CM; Chung, CM; Hsiao, JF; Hsu, JT; Pan, KL; Yang, TY1
Fujimura, T; Mineki, R; Murayama, K; Okumura, K; Seko, Y; Taka, H; Yao, T1
Baranyai, T; Ferdinandy, P; Giricz, Z; Károlyi-Szabó, M; Koncsos, G; Makkos, A; Nagy, CT; Onódi, Z; Varga, ZV1
Bruschetta, G; Campolo, M; Cordaro, M; Crupi, R; Cuzzocrea, S; Di Paola, R; Esposito, E; Fusco, R; Pugliatti, P; Siracusa, R1
Absi, T; Chepurko, E; Galindo, CL; Gumina, RJ; Harrell, FE; He, H; Huttinger, R; Kohr, MJ; Novitskaya, T; Roden, DM; Shaffer, CM; Song, Y; Su, YR; Varadharaj, S; Wells, QS; Wheeler, DG; Xu, M; Xu, Z; Zhang, B; Ziolo, MT; Zweier, JL1
Benetti, E; Collino, M; Cuzzocrea, S; Fantozzi, R; Gallicchio, M; Mazzon, E; Sivarajah, A; Thiemermann, C; Yasin, M1
Chen, CL; Chen, J; Chen, YR; Kaumaya, PPT; Rawale, S; Varadharaj, S; Zweier, JL1
Huliák, I; Juhász, L; Kiss, A; Végh, A1
Andreadou, I; Antoniadis, A; Farmakis, D; Fountoulaki, K; Ikonomidis, I; Iliodromitis, EK; Kremastinos, DT; Leftheriotis, D; Paraskevaidis, IA1
Chen, YR; Green-Church, KB; He, G; Liu, B; Tewari, AK; Zhang, L; Zweier, JL1
Kimura, S; Lu, XM; Matsuyoshi, H; Nishiyama, A; Shimizu, J; Takaki, M; Yu, YQ; Zhang, GX1
Csonka, C; Csont, T; Fekete, V; Ferdinandy, P; Kupai, K; Marais, de W; Odendaal, L; van Rooyen, J1
Castiglia, S; Collino, M; Fantozzi, R; Kapoor, A; Thiemermann, C1
Andreadou, I; Farmakis, D; Fotopoulou, T; Iliodromitis, EK; Ioannidis, K; Kremastinos, DT; Paraskevaidis, IA; Prokovas, E; Zoga, A1
Cai, X; Fu, F; Gao, F; Ji, L; Liu, W; Zhang, H; Zhang, L; Zheng, Q1
Gao, X; Ha, T; Hu, Y; Kao, RL; Kelley, J; Li, C; Liu, L; Lu, C; McMullen, JR; Williams, DL1
Hou, R; Lau, WB; Liu, S; Tao, L; Wang, H; Yin, T1
Chen, ML; Fan, Q; Ge, YG; Irwin, MG; Liu, SH; Liu, Y; Wang, LF; Wang, W; Xia, Z; Yang, XC; Zhang, LK1
Chen, LY; Hsin, HT; Liao, PC; Lin, PC; Wu, CF1
Liu, HR; Ma, XR; Tian, J; Wang, XL; Wu, Y; Xu, YW; Yan, L; Yang, GZ1
Blomeyer, C; Kehl, F; Lange, M; Lazariotto, M; Lotz, C; Pociej, J; Redel, A; Roewer, N; Schmidt, J; Smul, TM; Stumpner, J; Tischer-Zeitz, T1
Fujita, M; Ito, S; Iwasaka, T; Katano, T; Okazaki, T; Otani, H; Shimazu, T; Yoshioka, K1
Finegan, BA; Huang, Z; Irwin, MG; Ji, S; Liu, Y; Wong, GT; Xia, Z; Xia, ZY; Zhong, X1
Juni, RP; Moens, AL1
Merlino, A; Moro, F; Pagliaro, P; Parisella, ML; Penna, C; Perrelli, MG; Tullio, F1
Bakkaloglu, B; Gonenc, A; Griffiths, HR; Hacişevki, A; Simsek, B; Torun, M1
Juhász, L; Kaszaki, J; Kiss, A; Kovács, M; Nyeso, E; Seprényi, G; Végh, A1
Anna, F; Antonella, DS; Cappello, S; Di Stilo, A; Folino, A; Gianni, L; Losano, G; Pagliaro, P; Pasquale, P; Raffaella, R; Rastaldo, R; Sandra, C1
Banz, Y; Bovin, NV; Csizmadia, E; Gajanayake, T; Gordeeva, EA; Haeberli, A; Hess, OM; Korchagina, EY; Meier, P; Mettler, D; Rieben, R; Robson, SC1
Groves, JT; Karck, M; Loganathan, S; Merkely, B; Radovits, T; Szabó, C; Szabó, G1
Camara, AK; Gadicherla, AK; Kwok, WM; Stowe, DF; Wakim, BT; Yang, M; Zhou, Y1
Gao, C; Gao, E; Koch, W; Lau, WB; Lian, K; Liu, J; Liu, Y; Lu, X; Ma, Y; Qu, Y; Sun, L; Tao, L; Wang, H; Wang, R; Xia, C; Xu, A; Yang, L1
Barreto-Torres, G; Javadov, S; Parodi-Rullán, R1
Bencsik, P; Csonka, C; Csont, T; Ferdinandy, P; Kocsis, GF; Pálóczi, J; Pipicz, M; Sárközy, M; Varga, ZV1
Chen, B; Cui, Y; Huang, C; Ji, L; Li, R; Ma, L; Xing, W; Yu, J; Zhang, H; Zhang, W; Zhou, H1
Cuzzocrea, S; Mannaioni, PF; Marzocca, C; Masini, E; Mazzon, E; Salvemini, D1
Bock, A; Leitsch, T; Schimmer, M; Schultheiss, HP; Seligmann, C; Simsek, Y1
Bloch, W; Fischer, UM; Geissler, HJ; Hekmat, K; Klass, O; Krahwinkel, A; LaRosee, K; Mehlhorn, U; Suedkamp, M; Tossios, P1
Bloch, W; Easo, J; Fischer, JH; Fischer, UM; Geissler, HJ; Klass, O; Mehlhorn, U; Stock, U1
Borman, JB; Goldstein, S; Hoffman, A; Samuni, A; Schwalb, H1
Fukuyama, N; Hayashi, Y; Matsuda, H; Miyamoto, Y; Nakazawa, H; Sawa, Y; Takahashi, T1
Berrino, L; Cuzzocrea, S; D'Amico, M; Di Filippo, C; Esposito, K; Giugliano, D; Marfella, R; Nappo, F; Piegari, E; Rossi, F1
Arenas, IA; Armstrong, SJ; Davidge, ST; Pehowich, DJ; Xu, Y1
Duncker, DJ; Gho, BC; Gho, CC; Kazim, S; Liem, DA; Manintveld, OC; Verdouw, PD1
Berrino, L; Cuzzocrea, S; D'Amico, M; Di Filippo, C; Fabbroni, V; Giugliano, D; Marfella, R; Rossi, F; Scollo, G1
Braunwald, E; Cannon, CP; Demopoulos, LA; DiBattiste, PM; Gibson, CM; Murphy, SA; Singh, KP1
Angioli, P; Baldassarre, S; Bolognese, L; Burali, A; Ducci, K; Falsini, G; Liistro, F1
Coull, BM; McDonagh, PF; Ritter, LS; Stempel, KM1
Baldwin, WM; Becker, LC; Dipaula, A; Fox-Talbot, K; Irani, K; Khanday, F; Mattagajasingh, S; Ozaki, M; Yang, XP1
Gehl, HB; Giannitsis, E; Katus, HA; Kulke, C; Lehrke, S; Lima, JA; Merten, C; Richardt, G; Schuster, L; Steen, H; Wiegand, UK1
Ayaz, L; Aytacoglu, B; Bayri, O; Dikmengil, M; Döndaş, A; Ozeren, M; Sucu, N; Tamer, L1
Fukunaga, K; Hashimoto, M; Hisa, H; Kasahara, J; Shirasaki, Y; Takada, Y; Takeuchi, Y1
Paolocci, N1
Christopher, TA; Fan, Q; Gao, F; Lopez, BL; Ma, XL; Zhang, L1
Brookes, PS; Burwell, LS; Digerness, SB; Holman, WL; Tompkins, AJ; Zaragoza, C1
Chen, JL; Chen, ZJ; Gao, RL; Jing, ZC; Meng, L; Tian, Y; Wu, YJ; Yang, WX; Yang, YJ; You, SJ; Zhao, JL1
Bencsik, P; Cakici, I; Csonka, C; Csont, T; Ferdinandy, P; Fodor, G; Giricz, Z; Gyöngyösi, M; Turan, N1
Ananthakrishnan, R; Bakr, S; Bucciarelli, LG; Gomez, T; Harja, E; Hwang, YC; Kaneko, M; Lee, LK; Lerner, S; Li, Q; Lu, Y; Qu, W; Ramasamy, R; Schmidt, AM; Song, F; Yan, SF; Zou, YS1
Gao, E; Grunwald, Z; Hu, A; Jiao, X; Koch, WJ; Ma, XL; Sharifi-Azad, S; Sun, JZ1
Ambrosio, G; Bettini, M; Biondi, R; Cardounel, AJ; Liebgott, T; Tritto, I; Zweier, JL1
Cao, XB; Fan, Q; Gao, F; Liu, XL; Wang, SY; Yang, SL; Yang, XC1
Liao, WQ; Neuzil, J; Witting, PK1
Al-Shabrawey, M; Caldwell, RB; Caldwell, RW; Datar, R; Guo, D; Johnson, JA; Ma, G; Tawfik, HE1
Chan, L; Christopher, TA; Gao, E; Goldstein, BJ; Jiao, X; Koch, W; Li, S; Lopez, BL; Ma, XL; Tao, L; Yuan, Y1
Assemand, E; Chahine, R; Lacroix, M; Mateescu, MA; Nadeau, R1
Babu, GJ; Bhupathy, P; Cardounel, AJ; Kalyanasundaram, A; Periasamy, M; Talukder, MA; Zhao, X; Zuo, L; Zweier, JL1
Hsieh, YJ; Levitsky, S; McCully, JD; Wakiyama, H1
Chen, J; Dandapat, A; Fujita, Y; Hermonat, PL; Hu, C; Inoue, N; Jishage, K; Kawase, Y; Li, D; Mehta, JL; Sawamura, T; Suzuki, H1
Cuzzocrea, S; Salzman, AL; Szabó, C; Zingarelli, B; Zsengellér, Z1
Galiñanes, M; Zhang, JG1
Gurzenda, EM; Powell, SR; Wahezi, SE1
Al-Affar, EB; Liaudet, L; Szabó, C; Yang, Z1
Csonka, C; Csont, T; Ferdinandy, P; Onody, A1
Bissing, JW; Buettner, GR; Kerber, RE; Kregel, KC; Martin, SM; Miller, FJ; Ryan, AJ; Xu, L; Zhang, Y1
Fukuyama, N; Hayashi, Y; Matsuda, H; Nakazawa, H; Ohtake, S; Sawa, Y1
Denenberg, A; Hake, PW; O'Connor, M; Wong, HR; Yang, Z; Zingarelli, B1
Christopher, TA; Gao, E; Gao, F; Lopez, BL; Ma, XL; McLaughlin, R; Mo, QZ; Yan, WL; Yao, CL1

Trials

7 trial(s) available for tyrosine and Injury, Myocardial Reperfusion

ArticleYear
Staccato reperfusion prevents reperfusion injury in patients undergoing coronary angioplasty: a 1-year follow-up pilot study.
    Atherosclerosis, 2009, Volume: 204, Issue:2

    Topics: Acute Coronary Syndrome; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Biomarkers; Coronary Stenosis; Female; Follow-Up Studies; Humans; Male; Malondialdehyde; Middle Aged; Myocardial Contraction; Myocardial Infarction; Myocardial Reperfusion; Myocardial Reperfusion Injury; Myocardium; Oxidative Stress; Pilot Projects; Recovery of Function; Secondary Prevention; Stents; Time Factors; Treatment Outcome; Tyrosine; Ultrasonography; Ventricular Function, Left

2009
Postconditioning attenuates myocardial injury by reducing nitro-oxidative stress in vivo in rats and in humans.
    Clinical science (London, England : 1979), 2011, Volume: 120, Issue:6

    Topics: Aged; Angioplasty, Balloon, Coronary; Animals; Apoptosis; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Humans; Ischemic Postconditioning; Leukocyte Count; Male; Malondialdehyde; Middle Aged; Molsidomine; Myocardial Infarction; Myocardial Reperfusion Injury; Nitric Oxide Synthase Type II; Oxidative Stress; Rats; Rats, Sprague-Dawley; Treatment Outcome; Tyrosine; Ventricular Function, Left

2011
Upstream tirofiban reduces reperfusion cardiac arrhythmias in patients of acute ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention.
    International journal of cardiology, 2011, Jan-21, Volume: 146, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Arrhythmias, Cardiac; Female; Fibrinolytic Agents; Humans; Male; Middle Aged; Myocardial Infarction; Myocardial Reperfusion Injury; Tirofiban; Tyrosine; Young Adult

2011
Synergy of isoflurane preconditioning and propofol postconditioning reduces myocardial reperfusion injury in patients.
    Clinical science (London, England : 1979), 2011, Volume: 121, Issue:2

    Topics: Aged; Anesthetics, Inhalation; Anesthetics, Intravenous; Antioxidants; Coronary Artery Bypass; Cytokines; Drug Synergism; Female; Hemodynamics; Humans; Inflammation Mediators; Ischemic Postconditioning; Ischemic Preconditioning, Myocardial; Isoflurane; Male; Middle Aged; Myocardial Reperfusion Injury; Nitric Oxide Synthase Type III; Propofol; Tyrosine

2011
Leukocyte-depleted terminal blood cardioplegia provides superior myocardial protective effects in association with myocardium-derived nitric oxide and peroxynitrite production for patients undergoing prolonged aortic crossclamping for more than 120 minute
    The Journal of thoracic and cardiovascular surgery, 2003, Volume: 126, Issue:6

    Topics: Adolescent; Adult; Aged; Aorta; Aortic Valve; Blood; Cardioplegic Solutions; Constriction; Female; Heart Arrest, Induced; Humans; Inflammation Mediators; Leukapheresis; Leukocyte Elastase; Male; Middle Aged; Myocardial Reperfusion Injury; Myocardium; Neutrophils; Nitric Oxide; Peroxynitrous Acid; Tyrosine

2003
Association between duration of tirofiban therapy before percutaneous intervention and tissue level perfusion (a TACTICS-TIMI 18 substudy).
    The American journal of cardiology, 2004, Aug-15, Volume: 94, Issue:4

    Topics: Aged; Angina, Unstable; Angioplasty, Balloon, Coronary; Cardiac Catheterization; Coronary Angiography; Cost-Benefit Analysis; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Male; Microcirculation; Middle Aged; Myocardial Infarction; Myocardial Reperfusion Injury; Platelet Aggregation Inhibitors; Premedication; Thrombolytic Therapy; Tirofiban; Treatment Outcome; Tyrosine

2004
Very early cardiac magnetic resonance imaging for quantification of myocardial tissue perfusion in patients receiving tirofiban before percutaneous coronary intervention for ST-elevation myocardial infarction.
    American heart journal, 2005, Volume: 149, Issue:3

    Topics: Aged; Angioplasty, Balloon, Coronary; Coronary Angiography; Electrocardiography; Female; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Myocardial Infarction; Myocardial Reperfusion Injury; Pilot Projects; Platelet Glycoprotein GPIIb-IIIa Complex; Premedication; Prospective Studies; Stents; Tirofiban; Tyrosine

2005

Other Studies

86 other study(ies) available for tyrosine and Injury, Myocardial Reperfusion

ArticleYear
Tyrosine phosphorylation of eNOS regulates myocardial survival after an ischaemic insult: role of PYK2.
    Cardiovascular research, 2017, Jul-01, Volume: 113, Issue:8

    Topics: Animals; Enzyme Activation; Focal Adhesion Kinase 2; Hydrogen Peroxide; Male; Mice, Inbred C57BL; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Myocytes, Cardiac; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidative Stress; Phosphorylation; Rats; Tyrosine

2017
Alginate oligosaccharide alleviates myocardial reperfusion injury by inhibiting nitrative and oxidative stress and endoplasmic reticulum stress-mediated apoptosis.
    Drug design, development and therapy, 2017, Volume: 11

    Topics: Alginates; Animals; Apoptosis; Cardiotonic Agents; Disease Models, Animal; Endoplasmic Reticulum Stress; Male; Mice; Mice, Inbred C57BL; Myocardial Infarction; Myocardial Reperfusion Injury; Nitrosative Stress; Oligosaccharides; Oxidative Stress; Superoxides; Tyrosine

2017
Oxidative cross-linking of proteins to DNA following ischemia-reperfusion injury.
    Free radical biology & medicine, 2018, 05-20, Volume: 120

    Topics: Animals; DNA Adducts; Free Radicals; Male; Myocardial Reperfusion Injury; Myocytes, Cardiac; Oxidative Stress; Proteomics; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Thymidine; Tyrosine

2018
Protein kinases are involved in the cardioprotective effects activated by platelet glycoprotein IIb/IIIa inhibitor tirofiban at reperfusion in rats in vivo.
    European journal of pharmacology, 2018, Aug-05, Volume: 832

    Topics: Animals; Cardiotonic Agents; Enzyme Activation; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Phosphatidylinositol 3-Kinases; Platelet Glycoprotein GPIIb-IIIa Complex; Protein Kinase C-epsilon; Protein Kinases; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Tirofiban; Tyrosine

2018
The impact of sex and myocardial ischemic preconditioning on immunohistochemical markers of acute myocardial infarction.
    International journal of legal medicine, 2019, Volume: 133, Issue:2

    Topics: Animals; Biomarkers; Connexin 43; Female; Forensic Medicine; Immunohistochemistry; Ischemic Preconditioning, Myocardial; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Rats, Wistar; Sex Factors; Troponin I; Tyrosine

2019
Hydromorphine postconditioning protects isolated rat heart against ischemia-reperfusion injury via activating P13K/Akt/eNOS signaling.
    Cardiovascular therapeutics, 2018, Volume: 36, Issue:6

    Topics: Animals; Creatine Kinase, MB Form; Disease Models, Animal; Isolated Heart Preparation; Male; Morphine Derivatives; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Nitric Oxide; Nitric Oxide Synthase Type III; Phosphatidylinositol 3-Kinase; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats, Sprague-Dawley; Signal Transduction; Troponin T; Tyrosine

2018
Tyrosine nitration of mitochondrial proteins during myocardial ischemia and reperfusion.
    Journal of physiology and biochemistry, 2019, Volume: 75, Issue:2

    Topics: Aconitate Hydratase; Animals; Electron Transport Chain Complex Proteins; Male; Mass Spectrometry; Mitochondria, Heart; Mitochondrial Proteins; Myocardial Contraction; Myocardial Reperfusion Injury; Myocardial Stunning; Oxidation-Reduction; Rats; Rats, Wistar; Tyrosine

2019
Activation of cGMP/protein kinase G pathway in postconditioned myocardium depends on reduced oxidative stress and preserved endothelial nitric oxide synthase coupling.
    Journal of the American Heart Association, 2013, Jan-02, Volume: 2, Issue:1

    Topics: Animals; Biopterins; Cell Death; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Disease Models, Animal; Enzyme Activation; Enzyme Inhibitors; Ischemic Postconditioning; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Nitrates; Nitric Oxide Synthase Type III; Nitrites; Oxidative Stress; Phosphatidylinositol 3-Kinase; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Signal Transduction; Superoxides; Time Factors; Tyrosine

2013
High-fat, low-carbohydrate diet alters myocardial oxidative stress and impairs recovery of cardiac function after ischemia and reperfusion in obese rats.
    Nutrition research (New York, N.Y.), 2013, Volume: 33, Issue:4

    Topics: Adiponectin; Animals; Antioxidants; Catalase; Diet, Carbohydrate-Restricted; Diet, High-Fat; DNA Copy Number Variations; DNA, Mitochondrial; Glycogen; Insulin; Male; Mitochondrial Turnover; Myocardial Reperfusion Injury; Myocardium; NADPH Oxidase 4; NADPH Oxidases; Obesity; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Superoxide Dismutase; Tyrosine; Weight Loss; Xanthine Oxidase

2013
Cardioprotection by farnesol: role of the mevalonate pathway.
    Cardiovascular drugs and therapy, 2013, Volume: 27, Issue:4

    Topics: Animals; Animals, Newborn; Cardiotonic Agents; Cell Survival; Cells, Cultured; Cholesterol; Dolichols; Farnesol; Male; Mevalonic Acid; Myocardial Reperfusion Injury; Myocardium; Myocytes, Cardiac; Protein Prenylation; Rats; Rats, Wistar; Tyrosine; Ubiquinone

2013
The selective 5-LOX inhibitor 11-keto-β-boswellic acid protects against myocardial ischemia reperfusion injury in rats: involvement of redox and inflammatory cascades.
    Naunyn-Schmiedeberg's archives of pharmacology, 2013, Volume: 386, Issue:9

    Topics: Animals; Arachidonate 5-Lipoxygenase; Cardiotonic Agents; Caspase 3; Cyclooxygenase 2; DNA Fragmentation; Gene Expression Regulation; Glutathione Peroxidase; Heme Oxygenase (Decyclizing); Intercellular Adhesion Molecule-1; Lipoxygenase Inhibitors; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; NF-E2-Related Factor 2; NF-kappa B; Oxidation-Reduction; Peroxidase; Rats; Rats, Wistar; Triterpenes; Tumor Necrosis Factor-alpha; Tyrosine

2013
Breathing nitric oxide plus hydrogen gas reduces ischemia-reperfusion injury and nitrotyrosine production in murine heart.
    American journal of physiology. Heart and circulatory physiology, 2013, Aug-15, Volume: 305, Issue:4

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Administration, Inhalation; Aldehydes; Animals; Antioxidants; Cardiotonic Agents; Deoxyguanosine; Disease Models, Animal; Dose-Response Relationship, Drug; Down-Regulation; Gases; Hydrogen; Immunohistochemistry; Inhalation; Male; Mice; Mice, Inbred C57BL; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Neutrophil Infiltration; Nitric Oxide; Oxidative Stress; Receptors, Cell Surface; Time Factors; Tyrosine; Ventricular Function, Left

2013
Peroxynitrite is a key mediator of the cardioprotection afforded by ischemic postconditioning in vivo.
    PloS one, 2013, Volume: 8, Issue:7

    Topics: Animals; Cardiotonic Agents; Cytoprotection; Heart; Ischemic Postconditioning; Male; Metalloporphyrins; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Peroxynitrous Acid; Rats; Rats, Wistar; Tyrosine

2013
Susceptibility to myocardial ischemia reperfusion injury at early stage of type 1 diabetes in rats.
    Cardiovascular diabetology, 2013, Sep-17, Volume: 12

    Topics: Animals; Biomarkers; Caspase 3; Creatine Kinase, BB Form; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Dinoprost; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; L-Lactate Dehydrogenase; Male; Myocardial Contraction; Myocardial Infarction; Myocardial Reperfusion; Myocardial Reperfusion Injury; Myocardium; Nitric Oxide; Oxidative Stress; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Severity of Illness Index; STAT3 Transcription Factor; Stroke Volume; Superoxide Dismutase; Time Factors; Tumor Necrosis Factor-alpha; Tyrosine; Ventricular Function, Left; Ventricular Pressure

2013
The natural olive constituent oleuropein induces nutritional cardioprotection in normal and cholesterol-fed rabbits: comparison with preconditioning.
    Planta medica, 2015, Volume: 81, Issue:8

    Topics: Animals; Cholesterol; Disease Models, Animal; Hypercholesterolemia; Iridoid Glucosides; Iridoids; Male; Malondialdehyde; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Olea; Oxidative Stress; Phosphatidylinositol 3-Kinases; Protective Agents; Rabbits; Signal Transduction; Tyrosine

2015
Effect of sodium nitrite on ischaemia and reperfusion-induced arrhythmias in anaesthetized dogs: is protein S-nitrosylation involved?
    PloS one, 2015, Volume: 10, Issue:4

    Topics: Administration, Intravenous; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disease Models, Animal; Dogs; Hemodynamics; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Nitrates; Nitric Oxide; Nitrites; Protein Processing, Post-Translational; Sodium Nitrite; Superoxides; Tyrosine

2015
Platelet Glycoprotein IIb/IIIa Inhibitor Tirofiban Ameliorates Cardiac Reperfusion Injury.
    International heart journal, 2015, May-13, Volume: 56, Issue:3

    Topics: Animals; Apoptosis; In Situ Nick-End Labeling; Malondialdehyde; Myocardial Reperfusion Injury; Myocardium; Peroxidase; Platelet Glycoprotein GPIIb-IIIa Complex; Rats; Rats, Sprague-Dawley; Tirofiban; Tyrosine

2015
Secreted tyrosine sulfated-eIF5A mediates oxidative stress-induced apoptosis.
    Scientific reports, 2015, Sep-08, Volume: 5

    Topics: Animals; Antibodies, Monoclonal; Antibodies, Neutralizing; Apoptosis; Disease Models, Animal; Eukaryotic Translation Initiation Factor 5A; Golgi Apparatus; Humans; Hypoxia; Male; Models, Biological; Myocardial Reperfusion Injury; Myocytes, Cardiac; Oxidative Stress; Oxygen; Peptide Fragments; Peptide Initiation Factors; Protein Transport; Rats; RNA-Binding Proteins; Signal Transduction; trans-Golgi Network; Tyrosine

2015
Acute hyperglycemia abolishes cardioprotection by remote ischemic perconditioning.
    Cardiovascular diabetology, 2015, Nov-18, Volume: 14

    Topics: Animals; Apoptosis Regulatory Proteins; Arrhythmias, Cardiac; Autophagy; Autophagy-Related Protein 7; Autophagy-Related Protein-1 Homolog; Beclin-1; Heat-Shock Proteins; Hyperglycemia; Intracellular Signaling Peptides and Proteins; Ischemic Preconditioning, Myocardial; Myocardial Infarction; Myocardial Reperfusion Injury; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Sequestosome-1 Protein; Severity of Illness Index; Signal Transduction; Stress, Physiological; TOR Serine-Threonine Kinases; Tyrosine; Ubiquitin-Activating Enzymes

2015
Protective Effects of Ultramicronized Palmitoylethanolamide (PEA-um) in Myocardial Ischaemia and Reperfusion Injury in VIVO.
    Shock (Augusta, Ga.), 2016, Volume: 46, Issue:2

    Topics: Amides; Animals; Ethanolamines; Immunohistochemistry; Intercellular Adhesion Molecule-1; Interleukin-1beta; Male; Mice; Mice, Knockout; Microtomy; Myocardial Ischemia; Myocardial Reperfusion Injury; P-Selectin; Palmitic Acids; PPAR alpha; Rats, Wistar; Tumor Necrosis Factor-alpha; Tyrosine

2016
    Circulation. Heart failure, 2017, Volume: 10, Issue:2

    Topics: Adult; Animals; Calcium Channels, L-Type; Calcium Signaling; Calcium-Binding Proteins; Cardiomyopathies; Case-Control Studies; Disease Models, Animal; Female; Genetic Predisposition to Disease; Humans; Male; Mice, Inbred C57BL; Mice, Knockout; Middle Aged; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Oxidative Stress; Phenotype; Potassium Channels, Inwardly Rectifying; Reactive Nitrogen Species; Reactive Oxygen Species; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Tyrosine; Ventricular Dysfunction, Left; Ventricular Function, Left; Ventricular Pressure

2017
Anti-apoptotic and anti-inflammatory effects of hydrogen sulfide in a rat model of regional myocardial I/R.
    Shock (Augusta, Ga.), 2009, Volume: 31, Issue:3

    Topics: Active Transport, Cell Nucleus; Animals; Anti-Arrhythmia Agents; Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Cardiotonic Agents; Cell Nucleus; Decanoic Acids; Disease Models, Animal; Drug Antagonism; Hydroxy Acids; Male; Malondialdehyde; Muscle Proteins; Myocardial Reperfusion Injury; Neutrophils; Phosphorylation; Rats; Rats, Wistar; Sulfides; Tyrosine

2009
Protein tyrosine nitration of the flavin subunit is associated with oxidative modification of mitochondrial complex II in the post-ischemic myocardium.
    The Journal of biological chemistry, 2008, Oct-10, Volume: 283, Issue:41

    Topics: Animals; Cattle; Electron Transport Complex II; Mitochondria, Heart; Myocardial Reperfusion Injury; Myocardium; Nitric Oxide; Oxidation-Reduction; Peroxynitrous Acid; Protein Processing, Post-Translational; Rats; Rats, Sprague-Dawley; Superoxides; Tyrosine

2008
Peroxynitrite decreases arrhythmias induced by ischaemia reperfusion in anaesthetized dogs, without involving mitochondrial KATP channels.
    British journal of pharmacology, 2008, Volume: 155, Issue:7

    Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Coronary Vessels; Decanoic Acids; Dogs; Female; Hydroxy Acids; Male; Myocardial Reperfusion Injury; Peroxynitrous Acid; Potassium Channels; Severity of Illness Index; Survival Rate; Tyrosine; Ventricular Fibrillation

2008
Proteomic analysis of protein tyrosine nitration after ischemia reperfusion injury: mitochondria as the major target.
    Biochimica et biophysica acta, 2009, Volume: 1794, Issue:3

    Topics: Animals; Blotting, Western; Electron Transport Complex I; Electrophoresis, Gel, Two-Dimensional; Mice; Mitochondria, Heart; Mitochondrial Proteins; Myocardial Reperfusion Injury; Nitrates; Proteomics; Tandem Mass Spectrometry; Tyrosine

2009
The opposite roles of nNOS in cardiac ischemia-reperfusion-induced injury and in ischemia preconditioning-induced cardioprotection in mice.
    The journal of physiological sciences : JPS, 2009, Volume: 59, Issue:4

    Topics: Animals; Apoptosis; Enzyme Inhibitors; Free Radical Scavengers; Ischemic Preconditioning, Myocardial; Lipid Peroxidation; Metalloporphyrins; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Nitric Oxide Synthase Type I; Ornithine; Oxidative Stress; Reactive Nitrogen Species; Thiobarbituric Acid Reactive Substances; Tyrosine

2009
Cholesterol diet-induced hyperlipidemia impairs the cardioprotective effect of postconditioning: role of peroxynitrite.
    American journal of physiology. Heart and circulatory physiology, 2009, Volume: 297, Issue:5

    Topics: Animals; Biomarkers; Cholesterol, Dietary; Disease Models, Animal; Hyperlipidemias; Male; Metalloporphyrins; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Peroxynitrous Acid; Rats; Signal Transduction; Stress, Physiological; Tyrosine

2009
Activation of peroxisome proliferator-activated receptor-beta/delta attenuates myocardial ischemia/reperfusion injury in the rat.
    Shock (Augusta, Ga.), 2010, Volume: 34, Issue:2

    Topics: Animals; Cyclooxygenase 2; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hemodynamics; Male; Myocardial Reperfusion Injury; Myocardium; Nitric Oxide Synthase Type II; Oxazoles; Phosphorylation; PPAR alpha; PPAR delta; PPAR-beta; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Thiazoles; Tyrosine

2010
Simvastatin in contrast to postconditioning reduces infarct size in hyperlipidemic rabbits: possible role of oxidative/nitrosative stress attenuation.
    Basic research in cardiology, 2010, Volume: 105, Issue:2

    Topics: Animals; Anticholesteremic Agents; Biomarkers; Cholesterol, LDL; Hemodynamics; Hypercholesterolemia; Male; Malondialdehyde; Myocardial Reperfusion Injury; Myocardium; Nitrates; Nitrites; Oxidative Stress; Rabbits; Simvastatin; Tyrosine

2010
Insulin attenuates myocardial ischemia/reperfusion injury via reducing oxidative/nitrative stress.
    American journal of physiology. Endocrinology and metabolism, 2010, Volume: 298, Issue:4

    Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Caspase 3; Creatine Kinase; Electrocardiography; Heart Function Tests; Hypoglycemic Agents; In Situ Nick-End Labeling; Insulin; L-Lactate Dehydrogenase; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Necrosis; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reactive Nitrogen Species; Reperfusion Injury; Tyrosine

2010
TLR2 ligands induce cardioprotection against ischaemia/reperfusion injury through a PI3K/Akt-dependent mechanism.
    Cardiovascular research, 2010, Sep-01, Volume: 87, Issue:4

    Topics: Animals; Cardiotonic Agents; Cell Line; Disease Models, Animal; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hemodynamics; Ligands; Lipopeptides; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Neutrophil Infiltration; Peptidoglycan; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Rats; Signal Transduction; Time Factors; Toll-Like Receptor 2; Tyrosine; Ventricular Function

2010
Nitrative inactivation of thioredoxin-1 increases vulnerability of diabetic hearts to ischemia/reperfusion injury.
    Journal of molecular and cellular cardiology, 2010, Volume: 49, Issue:3

    Topics: Animals; Apoptosis; Blood Glucose; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Heart; Hyperglycemia; Immunoblotting; Immunoprecipitation; Mice; Myocardial Reperfusion Injury; Nitrates; Nitrosation; p38 Mitogen-Activated Protein Kinases; Peroxynitrous Acid; Thioredoxins; Tyrosine

2010
[Establishment and application of double-antibody sandwich ELISA for determination of 3-nitrotyrosine].
    Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, 2009, Volume: 25, Issue:4

    Topics: Animals; Antibodies, Monoclonal; Enzyme-Linked Immunosorbent Assay; Male; Myocardial Reperfusion Injury; Myocardium; Peroxynitrous Acid; Rats; Rats, Wistar; Sensitivity and Specificity; Tyrosine

2009
Activation of peroxisome-proliferator-activated receptors α and γ mediates remote ischemic preconditioning against myocardial infarction in vivo.
    Experimental biology and medicine (Maywood, N.J.), 2011, Volume: 236, Issue:1

    Topics: Anilides; Animals; Ischemic Preconditioning, Myocardial; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxazoles; PPAR alpha; PPAR gamma; Prostaglandin D2; Rabbits; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tyrosine

2011
Reversal of inducible nitric oxide synthase uncoupling unmasks tolerance to ischemia/reperfusion injury in the diabetic rat heart.
    Journal of molecular and cellular cardiology, 2011, Volume: 50, Issue:3

    Topics: Animals; Biopterins; Cyclic GMP; Diabetes Complications; Diabetes Mellitus, Experimental; Dithiothreitol; Imines; Male; Myocardial Reperfusion Injury; Nitric Oxide; Nitric Oxide Synthase Type II; Oxadiazoles; Oxidative Stress; Quinoxalines; Rats; Rats, Sprague-Dawley; Superoxides; Tiopronin; Tyrosine; Up-Regulation; Ventricular Function, Left

2011
Modulating iNOS-uncoupling: a new therapeutic avenue to tackle reperfusion-injury?
    Journal of molecular and cellular cardiology, 2011, Volume: 50, Issue:5

    Topics: Animals; Biopterins; Cyclic GMP; Diabetes Complications; Diabetes Mellitus, Experimental; Dithiothreitol; Imines; Male; Myocardial Reperfusion Injury; Nitric Oxide; Nitric Oxide Synthase Type II; Oxadiazoles; Oxidative Stress; Quinoxalines; Rats; Rats, Sprague-Dawley; Superoxides; Tiopronin; Tyrosine; Up-Regulation; Ventricular Function, Left

2011
Post-ischemic early acidosis in cardiac postconditioning modifies the activity of antioxidant enzymes, reduces nitration, and favors protein S-nitrosylation.
    Pflugers Archiv : European journal of physiology, 2011, Volume: 462, Issue:2

    Topics: Acidosis; Animals; Catalase; Male; Myocardial Ischemia; Myocardial Reperfusion Injury; Rats; Rats, Wistar; Superoxide Dismutase; Tyrosine

2011
Free radical reaction products and antioxidant capacity in beating heart coronary artery surgery compared to conventional bypass.
    Biochemistry. Biokhimiia, 2011, Volume: 76, Issue:6

    Topics: Aged; Antioxidants; beta Carotene; Coronary Artery Bypass; Coronary Artery Bypass, Off-Pump; Female; Free Radicals; Humans; Hydrogen Peroxide; Male; Middle Aged; Myocardial Reperfusion Injury; Nitric Oxide; Oxidative Stress; Protein Carbonylation; Tyrosine; Vitamin E

2011
Is there a trigger role of peroxynitrite in the anti-arrhythmic effect of ischaemic preconditioning and peroxynitrite infusion?
    European journal of pharmacology, 2011, Sep-30, Volume: 667, Issue:1-3

    Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Arterial Occlusive Diseases; Coronary Vessels; Dogs; Female; Heart Ventricles; Hemodynamics; Hydrogen-Ion Concentration; Infusions, Intra-Arterial; Ischemic Preconditioning, Myocardial; Male; Myocardial Reperfusion Injury; Nitrates; Nitrites; Peroxynitrous Acid; Superoxides; Time Factors; Tyrosine; Uric Acid

2011
A lipophilic nitric oxide donor and a lipophilic antioxidant compound protect rat heart against ischemia-reperfusion injury if given as hybrid molecule but not as a mixture.
    Journal of cardiovascular pharmacology, 2012, Volume: 59, Issue:3

    Topics: Animals; Antioxidants; Cardiotonic Agents; Drug Synergism; Ischemic Postconditioning; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Nitric Oxide; Nitric Oxide Donors; Rats; Rats, Wistar; Tyrosine

2012
Evaluation of multimeric tyrosine-O-sulfate as a cytoprotectant in an in vivo model of acute myocardial infarction in pigs.
    Cardiology, 2012, Volume: 121, Issue:1

    Topics: Animals; Anticoagulants; Complement Inactivating Agents; Complement Pathway, Classical; Cytoprotection; Dose-Response Relationship, Drug; Granulocytes; Hemodynamics; Myocardial Infarction; Myocardial Reperfusion; Myocardial Reperfusion Injury; Neutrophils; Sus scrofa; Thromboplastin; Tyrosine; Ventricular Fibrillation

2012
Catalytic peroxynitrite decomposition improves reperfusion injury after heart transplantation.
    The Journal of thoracic and cardiovascular surgery, 2012, Volume: 143, Issue:6

    Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Animals; Biomarkers; Coronary Circulation; Disease Models, Animal; Endothelium, Vascular; Energy Metabolism; Heart Transplantation; Immunohistochemistry; Male; Metalloporphyrins; Myocardial Reperfusion Injury; Myocardium; Oxidative Stress; Peroxynitrous Acid; Poly Adenosine Diphosphate Ribose; Rats; Rats, Inbred Lew; Time Factors; Tyrosine; Vasodilation; Ventricular Function, Left; Ventricular Pressure

2012
Tyrosine nitration of voltage-dependent anion channels in cardiac ischemia-reperfusion: reduction by peroxynitrite scavenging.
    Biochimica et biophysica acta, 2012, Volume: 1817, Issue:11

    Topics: Animals; Guinea Pigs; Mass Spectrometry; Mitochondrial Proteins; Myocardial Reperfusion Injury; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Peroxynitrous Acid; Resveratrol; Stilbenes; Superoxides; Tyrosine; Voltage-Dependent Anion Channels

2012
The alternative crosstalk between RAGE and nitrative thioredoxin inactivation during diabetic myocardial ischemia-reperfusion injury.
    American journal of physiology. Endocrinology and metabolism, 2012, Oct-01, Volume: 303, Issue:7

    Topics: Acetophenones; Animals; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Free Radical Scavengers; Imines; Lysine; Male; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Myocardial Reperfusion Injury; NADPH Oxidase 2; NADPH Oxidases; Nitric Oxide Synthase Type II; Organometallic Compounds; Receptor for Advanced Glycation End Products; Receptors, Immunologic; RNA, Small Interfering; Salicylates; Superoxides; Thioredoxins; Tyrosine

2012
The role of PPARα in metformin-induced attenuation of mitochondrial dysfunction in acute cardiac ischemia/reperfusion in rats.
    International journal of molecular sciences, 2012, Volume: 13, Issue:6

    Topics: Animals; Electron Transport Complex I; Electron Transport Complex II; Hypoglycemic Agents; L-Lactate Dehydrogenase; Male; Metformin; Mitochondria, Heart; Myocardial Reperfusion Injury; Myocytes, Cardiac; Oxazoles; PPAR alpha; Rats; Rats, Sprague-Dawley; Tyrosine

2012
Preconditioning protects the heart in a prolonged uremic condition.
    American journal of physiology. Heart and circulatory physiology, 2012, Nov-15, Volume: 303, Issue:10

    Topics: Angiotensin II; Animals; Biomarkers; Creatinine; Disease Models, Animal; Ischemic Preconditioning, Myocardial; Male; Myocardial Contraction; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Nephrectomy; Proteinuria; Rats; Rats, Wistar; Stroke Volume; Time Factors; Tyrosine; Ultrasonography; Urea; Uremia; Uric Acid; Ventricular Function, Left

2012
Catalpol decreases peroxynitrite formation and consequently exerts cardioprotective effects against ischemia/reperfusion insult.
    Pharmaceutical biology, 2013, Volume: 51, Issue:4

    Topics: Animals; Antioxidants; Apoptosis; Cardiotonic Agents; Disease Models, Animal; Down-Regulation; Enzyme Activation; Free Radical Scavengers; Injections, Intraperitoneal; Iridoid Glucosides; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Necrosis; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxidative Stress; Peroxynitrous Acid; Phosphatidylinositol 3-Kinase; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Time Factors; Tyrosine

2013
Protective effects of M40403, a selective superoxide dismutase mimetic, in myocardial ischaemia and reperfusion injury in vivo.
    British journal of pharmacology, 2002, Volume: 136, Issue:6

    Topics: Animals; Cardiotonic Agents; Immunohistochemistry; Intercellular Adhesion Molecule-1; Male; Manganese; Molecular Mimicry; Myocardial Ischemia; Myocardial Reperfusion Injury; Organometallic Compounds; P-Selectin; Peroxidase; Rats; Rats, Wistar; Superoxide Dismutase; Tyrosine

2002
Human thrombocytes are able to induce a myocardial dysfunction in the ischemic and reperfused guinea pig heart mediated by free radicals-role of the GPIIb/IIIa-blocker tirofiban.
    Life sciences, 2002, Sep-27, Volume: 71, Issue:19

    Topics: Animals; Blood Platelets; Cardiac Output; Disease Models, Animal; Fibrinolytic Agents; Guinea Pigs; Humans; In Vitro Techniques; Male; Myocardial Reperfusion Injury; Platelet Glycoprotein GPIIb-IIIa Complex; Platelet Transfusion; Superoxide Dismutase; Tirofiban; Tyrosine

2002
Nitrotyrosine and 8-isoprostane formation indicate free radical-mediated injury in hearts of patients subjected to cardioplegia.
    The Journal of thoracic and cardiovascular surgery, 2003, Volume: 125, Issue:1

    Topics: Coronary Vessels; Cyclic GMP; Dinoprost; Endothelium, Vascular; F2-Isoprostanes; Female; Heart Arrest, Induced; Humans; Male; Middle Aged; Myocardial Reperfusion Injury; Nitric Oxide; Reactive Oxygen Species; Tyrosine

2003
Cardioplegic arrest induces apoptosis signal-pathway in myocardial endothelial cells and cardiac myocytes.
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2003, Volume: 23, Issue:6

    Topics: Animals; Apoptosis; Biomarkers; Cardiopulmonary Bypass; Caspase 3; Caspases; Dinoprost; Endothelium, Vascular; F2-Isoprostanes; Female; Heart Arrest, Induced; Immunohistochemistry; Male; Models, Animal; Myocardial Reperfusion Injury; Myocytes, Cardiac; Signal Transduction; Swine; Tyrosine

2003
Effect of nitric oxide and nitroxide SOD-mimic on the recovery of isolated rat heart following ischemia and reperfusion.
    Biochemical pharmacology, 2003, Oct-01, Volume: 66, Issue:7

    Topics: Animals; Heart; Hemodynamics; Kinetics; Myocardial Ischemia; Myocardial Reperfusion Injury; Nitric Oxide; Nitrogen Oxides; Oxygen Consumption; Rats; Reperfusion; Superoxide Dismutase; Tyrosine

2003
Absence of inducible nitric oxide synthase reduces myocardial damage during ischemia reperfusion in streptozotocin-induced hyperglycemic mice.
    Diabetes, 2004, Volume: 53, Issue:2

    Topics: Animals; Blood Glucose; Blood Pressure; Diabetes Mellitus, Experimental; Hyperglycemia; Insulin; Interleukins; Mice; Mice, Knockout; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Reference Values; RNA; Streptozocin; Tyrosine

2004
Cardioprotection by chronic estrogen or superoxide dismutase mimetic treatment in the aged female rat.
    American journal of physiology. Heart and circulatory physiology, 2004, Volume: 287, Issue:1

    Topics: Aging; Animals; Body Weight; Cardiotonic Agents; Estrogens; Ethylenediamines; Female; Heart; Heart Ventricles; Myocardial Ischemia; Myocardial Reperfusion Injury; NADPH Oxidases; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Organ Size; Organometallic Compounds; Ovariectomy; Rats; Rats, Sprague-Dawley; Recovery of Function; Superoxide Dismutase; Tyrosine; Uterus

2004
The tyrosine phosphatase inhibitor bis(maltolato)oxovanadium attenuates myocardial reperfusion injury by opening ATP-sensitive potassium channels.
    The Journal of pharmacology and experimental therapeutics, 2004, Volume: 309, Issue:3

    Topics: Adenosine Triphosphate; Animals; Blood Pressure; Cardiotonic Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Heart Rate; Male; Membrane Proteins; Myocardial Infarction; Myocardial Reperfusion Injury; Potassium Channels; Protein Tyrosine Phosphatases; Pyrones; Rats; Rats, Wistar; Time Factors; Tyrosine; Vanadates

2004
M40403 prevents myocardial injury induced by acute hyperglycaemia in perfused rat heart.
    European journal of pharmacology, 2004, Aug-16, Volume: 497, Issue:1

    Topics: Animals; Antioxidants; Cells, Cultured; DNA Damage; Endothelial Cells; Endothelium, Vascular; Glucose; Heart; Humans; In Vitro Techniques; Lipid Peroxidation; Male; Malondialdehyde; Manganese; Mitochondria; Myocardial Reperfusion Injury; Myocardium; Organometallic Compounds; Poly(ADP-ribose) Polymerases; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Superoxides; Tyrosine

2004
Elevations in troponin I after percutaneous coronary interventions are associated with abnormal tissue-level perfusion in high-risk patients with non-ST-segment-elevation acute coronary syndromes.
    Circulation, 2004, Sep-21, Volume: 110, Issue:12

    Topics: Abciximab; Acute Disease; Aged; Angina Pectoris; Angioplasty, Balloon, Coronary; Antibodies, Monoclonal; Aspirin; Biomarkers; Clopidogrel; Combined Modality Therapy; Coronary Angiography; Coronary Circulation; Electrocardiography; Female; Humans; Immunoglobulin Fab Fragments; Male; Middle Aged; Myocardial Ischemia; Myocardial Reperfusion Injury; Platelet Aggregation Inhibitors; Prospective Studies; Risk; Ticlopidine; Tirofiban; Troponin I; Tyrosine; Ultrasonography

2004
Leukocyte-platelet aggregates in rat peripheral blood after ischemic stroke and reperfusion.
    Biological research for nursing, 2005, Volume: 6, Issue:4

    Topics: Analysis of Variance; Animals; Anticoagulants; Biomarkers; Blood Platelets; Brain Ischemia; Disease Models, Animal; Flow Cytometry; Inflammation; Leukocytes; Male; Myocardial Reperfusion Injury; Neutrophil Activation; Neutrophils; Platelet Aggregation; Platelet Aggregation Inhibitors; Polysaccharides; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Severity of Illness Index; Stroke; Time Factors; Tirofiban; Tyrosine

2005
Signal transducer and activator of transcription 3alpha and specificity protein 1 interact to upregulate intercellular adhesion molecule-1 in ischemic-reperfused myocardium and vascular endothelium.
    Arteriosclerosis, thrombosis, and vascular biology, 2005, Volume: 25, Issue:7

    Topics: Animals; Cells, Cultured; Coronary Vessels; Endothelium, Vascular; Humans; Intercellular Adhesion Molecule-1; Interleukin-6; Male; Myocardial Reperfusion; Myocardial Reperfusion Injury; Phosphorylation; Promoter Regions, Genetic; rac1 GTP-Binding Protein; Rats; Rats, Inbred Lew; RNA Interference; RNA, Messenger; Sp1 Transcription Factor; STAT3 Transcription Factor; Transcriptional Activation; Tyrosine; Umbilical Veins; Up-Regulation

2005
Caffeic acid phenethyl ester (CAPE) supplemented St. Thomas' hospital cardioplegic solution improves the antioxidant defense system of rat myocardium during ischemia-reperfusion injury.
    Pharmacological research, 2005, Volume: 52, Issue:3

    Topics: Animals; Antioxidants; Caffeic Acids; Cardioplegic Solutions; Catalase; Free Radical Scavengers; Heart; In Vitro Techniques; Male; Malondialdehyde; Myocardial Reperfusion Injury; Peroxidase; Phenylethyl Alcohol; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase; Tyrosine

2005
Cytoprotective effect of 3-[2-[4-(3-chloro-2-methylphenyl)-1-piperazinyl]ethyl]-5,6-dimethoxy-1-(4-imidazolylmethyl)-1H-indazole dihydrochloride 3.5 hydrate (DY-9760e) against ischemia/reperfusion-induced injury in rat heart involves inhibition of fodrin
    Journal of pharmacological sciences, 2005, Volume: 98, Issue:2

    Topics: Animals; Blotting, Western; Carrier Proteins; Caspase 3; Caspase Inhibitors; Caspases; Enzyme Activation; Indazoles; Male; Microfilament Proteins; Myocardial Reperfusion Injury; Proteins; Rats; Rats, Sprague-Dawley; Tyrosine; Ventricular Function, Left

2005
Peroxynitrite like Pan?
    Cardiovascular research, 2005, Aug-01, Volume: 67, Issue:2

    Topics: Biomarkers; Cells, Cultured; Heart Failure; Humans; Myocardial Contraction; Myocardial Reperfusion Injury; Myocardium; Peroxynitrous Acid; Tyrosine

2005
Nitrate tolerance aggravates postischemic myocardial apoptosis and impairs cardiac functional recovery after ischemia.
    Apoptosis : an international journal on programmed cell death, 2005, Volume: 10, Issue:6

    Topics: Adaptation, Physiological; Animals; Apoptosis; Blood Pressure; Caspase 3; Creatine Kinase; Dietary Supplements; Enzyme Activation; Glutathione; Heart Rate; Heart Ventricles; L-Lactate Dehydrogenase; Male; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Myocytes, Cardiac; Nitrates; Nitroglycerin; Rats; Recovery of Function; Tyrosine; Vasodilation

2005
Mitochondrial dysfunction in cardiac ischemia-reperfusion injury: ROS from complex I, without inhibition.
    Biochimica et biophysica acta, 2006, Volume: 1762, Issue:2

    Topics: Animals; Electron Transport Complex I; Male; Mitochondria, Heart; Myocardial Ischemia; Myocardial Reperfusion Injury; Proteomics; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Sulfhydryl Compounds; Tyrosine

2006
[Effects of anti-platelet drugs on myocardial no-reflow after acute myocardial infarction and reperfusion: experiment with mini-swine model].
    Zhonghua yi xue za zhi, 2005, Aug-17, Volume: 85, Issue:31

    Topics: Animals; Clopidogrel; Coronary Circulation; Myocardial Infarction; Myocardial Reperfusion; Myocardial Reperfusion Injury; Platelet Aggregation Inhibitors; Random Allocation; Swine; Swine, Miniature; Thrombolytic Therapy; Ticlopidine; Tirofiban; Tyrosine

2005
The role of peroxynitrite in chemical preconditioning with 3-nitropropionic acid in rat hearts.
    Cardiovascular research, 2006, May-01, Volume: 70, Issue:2

    Topics: Animals; Biomarkers; Ischemic Preconditioning, Myocardial; L-Lactate Dehydrogenase; Male; Myocardial Reperfusion Injury; Myocardium; NADPH Oxidases; Nitric Oxide; Nitric Oxide Synthase; Nitro Compounds; Peroxynitrous Acid; Propionates; Rats; Rats, Wistar; Succinate Dehydrogenase; Superoxide Dismutase; Tyrosine; Xanthine Oxidase

2006
Receptor for advanced-glycation end products: key modulator of myocardial ischemic injury.
    Circulation, 2006, Mar-07, Volume: 113, Issue:9

    Topics: Animals; Cyclic GMP; Energy Metabolism; Male; Mice; Mice, Knockout; Myocardial Ischemia; Myocardial Reperfusion Injury; Nitric Oxide; Nitric Oxide Synthase Type II; Rats; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Tyrosine; Up-Regulation

2006
Chronic beta-adrenergic receptor stimulation induces cardiac apoptosis and aggravates myocardial ischemia/reperfusion injury by provoking inducible nitric-oxide synthase-mediated nitrative stress.
    The Journal of pharmacology and experimental therapeutics, 2006, Volume: 318, Issue:2

    Topics: Adrenergic beta-Agonists; Animals; Apoptosis; Blotting, Western; C-Reactive Protein; Heart; Immunohistochemistry; In Situ Nick-End Labeling; Isoproterenol; Mice; Mice, Inbred C57BL; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type II; RNA; Stress, Physiological; Tyrosine

2006
Hydroxylation of D-phenylalanine as a novel approach to detect hydroxyl radicals: application to cardiac pathophysiology.
    Cardiovascular research, 2006, Jul-15, Volume: 71, Issue:2

    Topics: Animals; Biomarkers; Chromatography, High Pressure Liquid; Free Radical Scavengers; Hydroxyl Radical; Hydroxylation; Male; Mannitol; Myocardial Reperfusion Injury; Myocardium; Oxidation-Reduction; Perfusion; Phenylalanine; Protein Isoforms; Rats; Rats, Sprague-Dawley; Tyrosine

2006
Glutathione reverses peroxynitrite-mediated deleterious effects of nitroglycerin on ischemic rat hearts.
    Journal of cardiovascular pharmacology, 2006, Volume: 47, Issue:3

    Topics: Animals; Apoptosis; Glutathione; Male; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocytes, Cardiac; Nitroglycerin; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley; Tyrosine

2006
Expression of human myoglobin in H9c2 cells enhances toxicity to added hydrogen peroxide.
    Biochemical and biophysical research communications, 2006, Sep-22, Volume: 348, Issue:2

    Topics: Amino Acid Sequence; Animals; Apoptosis; Cells, Cultured; Cross-Linking Reagents; Heme; Humans; Hydrogen Peroxide; Myocardial Reperfusion Injury; Myocytes, Cardiac; Myoglobin; Rats; Reactive Oxygen Species; Transfection; Tyrosine

2006
Protection against myocardial ischemia/reperfusion injury by short-term diabetes: enhancement of VEGF formation, capillary density, and activation of cell survival signaling.
    Naunyn-Schmiedeberg's archives of pharmacology, 2006, Volume: 373, Issue:6

    Topics: Animals; Blood Pressure; Blotting, Western; Capillaries; Caspase 3; Cell Survival; Coronary Circulation; Diabetes Mellitus, Experimental; Heart Rate; Lipid Peroxidation; Male; Myocardial Reperfusion Injury; Myocardium; Neovascularization, Physiologic; Nitric Oxide; Nitric Oxide Synthase Type III; Oncogene Protein v-akt; Oxidative Stress; Phosphorylation; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Signal Transduction; Tyrosine; Vascular Endothelial Growth Factor A

2006
Adiponectin cardioprotection after myocardial ischemia/reperfusion involves the reduction of oxidative/nitrative stress.
    Circulation, 2007, Mar-20, Volume: 115, Issue:11

    Topics: Adiponectin; Animals; Apoptosis; Cardiotonic Agents; Cells, Cultured; Male; Membrane Glycoproteins; Mice; Mice, Knockout; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Myocytes, Cardiac; NADPH Oxidase 2; NADPH Oxidases; Nitric Oxide; Nitric Oxide Synthase Type II; Oxidative Stress; Peroxynitrous Acid; Reactive Nitrogen Species; Superoxides; Tumor Necrosis Factor-alpha; Tyrosine; Up-Regulation

2007
Gamma-irradiated ceruloplasmin affords antifibrillatory protection against ischemia/reperfusion damage in the isolated rat heart.
    International journal of radiation biology, 2007, Volume: 83, Issue:5

    Topics: Animals; Anti-Arrhythmia Agents; Antioxidants; Ceruloplasmin; Dose-Response Relationship, Radiation; Gamma Rays; Heart; Heart Rate; In Vitro Techniques; Myocardial Reperfusion Injury; Rats; Tyrosine; Ventricular Fibrillation

2007
Expression of SERCA isoform with faster Ca2+ transport properties improves postischemic cardiac function and Ca2+ handling and decreases myocardial infarction.
    American journal of physiology. Heart and circulatory physiology, 2007, Volume: 293, Issue:4

    Topics: Animals; Arrhythmias, Cardiac; Calcium; Coronary Circulation; Disease Models, Animal; Electron Spin Resonance Spectroscopy; Fluorescent Dyes; Free Radicals; Heterocyclic Compounds, 3-Ring; Immunohistochemistry; Isoenzymes; Mice; Mice, Transgenic; Mitochondria, Heart; Myocardial Contraction; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Sarcoplasmic Reticulum; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Spectrometry, Fluorescence; Time Factors; Tyrosine; Ventricular Function, Left; Ventricular Pressure

2007
Cardioplegia and diazoxide modulate STAT3 activation and DNA binding.
    The Annals of thoracic surgery, 2007, Volume: 84, Issue:4

    Topics: Animals; Apoptosis; Binding Sites; Blotting, Western; Cardioplegic Solutions; Diazoxide; Disease Models, Animal; DNA; Electrophoresis; Female; Heart Arrest, Induced; Ischemic Preconditioning, Myocardial; Male; Mitochondria, Heart; Myocardial Reperfusion Injury; Phosphorylation; Random Allocation; Sensitivity and Specificity; STAT3 Transcription Factor; Swine; Tyrosine

2007
LOX-1 abrogation reduces myocardial ischemia-reperfusion injury in mice.
    Journal of molecular and cellular cardiology, 2008, Volume: 44, Issue:1

    Topics: Animals; Creatine Kinase, MB Form; Gene Deletion; Hemodynamics; Malondialdehyde; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinases; Myocardial Reperfusion Injury; Myocardium; Nitric Oxide Synthase Type II; Oxidation-Reduction; Oxidative Stress; Proto-Oncogene Proteins c-akt; Scavenger Receptors, Class E; Signal Transduction; Superoxide Dismutase; Tyrosine

2008
Protection against myocardial ischemia and reperfusion injury by 3-aminobenzamide, an inhibitor of poly (ADP-ribose) synthetase.
    Cardiovascular research, 1997, Volume: 36, Issue:2

    Topics: Adenosine Triphosphate; Animals; Benzamides; Cells, Cultured; Creatine Kinase; Endothelium, Vascular; Enzyme Inhibitors; In Vitro Techniques; Male; Myocardial Reperfusion Injury; Myocardium; Peroxidase; Poly(ADP-ribose) Polymerase Inhibitors; Rats; Rats, Wistar; Tyrosine

1997
Role of the L-arginine/nitric oxide pathway in ischaemic/reoxygenation injury of the human myocardium.
    Clinical science (London, England : 1979), 2000, Volume: 99, Issue:6

    Topics: Analysis of Variance; Arginine; Culture Techniques; Enzyme Inhibitors; Formazans; Humans; L-Lactate Dehydrogenase; Myocardial Reperfusion Injury; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Donors; Nitroso Compounds; Tetrazolium Salts; Tissue Survival; Tyrosine

2000
Actin is oxidized during myocardial ischemia.
    Free radical biology & medicine, 2001, May-15, Volume: 30, Issue:10

    Topics: Actins; Animals; Blood Pressure; Heart; Heart Rate; Immunoblotting; In Vitro Techniques; Male; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion; Myocardial Reperfusion Injury; Myocardial Stunning; Myocardium; Oxidation-Reduction; Perfusion; Rats; Rats, Sprague-Dawley; Troponin T; Tyrosine; Ventricular Function, Left

2001
Myocardial ischemic preconditioning in rodents is dependent on poly (ADP-ribose) synthetase.
    Molecular medicine (Cambridge, Mass.), 2001, Volume: 7, Issue:6

    Topics: Animals; Benzamides; Enzyme Inhibitors; Immunohistochemistry; Interleukin-10; Interleukin-12; Ischemic Preconditioning, Myocardial; Male; Mice; Mice, Knockout; Myocardial Reperfusion Injury; Myocardium; NAD; Peroxidase; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases; Rats; Rats, Wistar; Tissue Extracts; Tumor Necrosis Factor-alpha; Tyrosine

2001
Preconditioning decreases ischemia/reperfusion-induced peroxynitrite formation.
    Biochemical and biophysical research communications, 2001, Aug-03, Volume: 285, Issue:5

    Topics: Animals; Aorta; Blood Flow Velocity; In Vitro Techniques; Ischemic Preconditioning, Myocardial; L-Lactate Dehydrogenase; Male; Myocardial Ischemia; Myocardial Reperfusion; Myocardial Reperfusion Injury; Myocardium; Nitrates; Rats; Rats, Wistar; Time Factors; Tyrosine; Ventricular Function, Left

2001
Nitric oxide synthase inhibitors decrease coronary sinus-free radical concentration and ameliorate myocardial stunning in an ischemia-reperfusion model.
    Journal of the American College of Cardiology, 2001, Volume: 38, Issue:2

    Topics: Animals; Ascorbic Acid; Dogs; Electron Spin Resonance Spectroscopy; Enzyme Inhibitors; Hemodynamics; Myocardial Contraction; Myocardial Reperfusion Injury; Myocardial Stunning; Myocardium; Nitric Oxide Synthase; Nitroarginine; Superoxides; Tyrosine

2001
Peroxynitrite formation from human myocardium after ischemia-reperfusion during open heart operation.
    The Annals of thoracic surgery, 2001, Volume: 72, Issue:2

    Topics: Adult; Aged; Cardiopulmonary Bypass; Creatine Kinase; Creatine Kinase, MB Form; Female; Heart Valve Prosthesis Implantation; Humans; Isoenzymes; Male; Malondialdehyde; Middle Aged; Myocardial Reperfusion Injury; Myocardium; Nitrates; Tyrosine

2001
Absence of inducible nitric oxide synthase modulates early reperfusion-induced NF-kappaB and AP-1 activation and enhances myocardial damage.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2002, Volume: 16, Issue:3

    Topics: Animals; Apoptosis; Cardiotonic Agents; Cytokines; HSP70 Heat-Shock Proteins; JNK Mitogen-Activated Protein Kinases; Kinetics; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitogen-Activated Protein Kinases; Models, Biological; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Neutrophil Infiltration; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Signal Transduction; Transcription Factor AP-1; Tyrosine

2002
Enhancement of glutathione cardioprotection by ascorbic acid in myocardial reperfusion injury.
    The Journal of pharmacology and experimental therapeutics, 2002, Volume: 301, Issue:2

    Topics: Animals; Antioxidants; Ascorbic Acid; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Glutathione; Heart; Heart Rate; Incidence; Lipid Peroxidation; Myocardial Reperfusion Injury; Myocardium; Protective Agents; Rats; Reperfusion Injury; Tachycardia; Tyrosine; Ventricular Fibrillation

2002