tyrosine and Hypoxia

tyrosine has been researched along with Hypoxia in 127 studies

Research

Studies (127)

TimeframeStudies, this research(%)All Research%
pre-199029 (22.83)18.7374
1990's6 (4.72)18.2507
2000's50 (39.37)29.6817
2010's40 (31.50)24.3611
2020's2 (1.57)2.80

Authors

AuthorsStudies
Bhadra, K; Chinnadurai, V; Gandhi, S; Gupta, I; Kanwar, RS1
Bao, Q; Li, G; Liu, C; Suo, Y; Yang, Q; Yuan, M; Zhang, B; Zhang, K; Zhang, Y1
deKay, RJ; Jernigan, NL; Resta, TC; Sheak, JR; Walker, BR; Weise-Cross, L1
Godo, S; Ikumi, Y; Ito, A; Kajitani, S; Saito, H; Sato, S; Shimokawa, H; Shiroto, T; Tanaka, S1
Arias, P; Iturriaga, R; Moya, EA1
Ergaz, Z; Ornoy, A; Weinstein-Fudim, L1
Angelone, T; Anouar, Y; Boukhzar, L; Cerra, MC; Filice, M; Gattuso, A; Imbrogno, S; Leo, S; Mallouki, BY; Mazza, R; Rocca, C1
Jiang, H; Lai, N; Lu, W; Ran, P; Wang, J; Xu, L; Yang, K; Zhang, Y; Zhong, N1
Fujita, T; Kawakami-Mori, F; Mu, S; Ogura, S; Shimosawa, T; Shirai, M; Sonobe, T; Uetake, Y; Wang, H; Yatomi, Y; Yoshida, K1
Balestra, C; Cialoni, D; Germonpré, P; Guerrero, F; Rozloznik, M; Sponsiello, N; Theunissen, S1
Debevec, T; Eiken, O; Mekjavic, IB; Millet, GP; Mury, P; Pialoux, V1
Angamo, EA; Bauer, NM; de Curtis, M; Hedrich, J; Librizzi, L; Luhmann, HJ; Zehendner, CM1
Cheng, Y; Fujimura, A; Ichikawa, T; Matsui, H; Michiue, H; Nishiki, T; Tani, Y; Tomizawa, K; Uneda, A; Wei, FY1
Cai, J; Cai, L; Cai, X; Tan, Y; Wang, Y; Zheng, Y; Zhou, S1
Bálint, Z; Dahal, BK; Kwapiszewska, G; Murmann, K; Schermuly, RT; Seeger, W; Veith, C; Weissmann, N; Wygrecka, M; Zakrzewicz, D1
Li, JX; Miao, ZH; Wang, Y; Wang, YQ1
Fujimura, T; Mineki, R; Murayama, K; Okumura, K; Seko, Y; Taka, H; Yao, T1
Cejuela, R; Debevec, T; Ehrström, S; Faiss, R; Millet, GP; Mury, P; Pialoux, V; Saugy, J; Schmitt, L1
Chen, KT; Fu, PI; Huang, CC; Jou, MJ; Lai, CJ; Tsai, MH; Wei, IH; Wu, CH; Wu, YC1
Debevec, T; Ehrström, S; Eiken, O; Mekjavic, IB; Millet, GP; Pialoux, V; Ribon, A1
Arias, P; Del Rio, R; Iturriaga, R; Moya, EA; Oyarce, MP; Varela, C1
Abdelsaid, M; Coucha, M; El-Remessy, AB; Ergul, A; Fagan, SC; Johnson, MH; Li, W; Orfi, L1
Bates, ML; Dopp, JM; Morgan, BJ; Rio, RD; Wang, Z1
Fu, J; Liu, X; Liu, Z; Ran, J; Shi, Q; Wang, N; Zheng, J; Zheng, X1
An, YM; Cong, X; Dou, D; Feng, H; Wu, LL; Zhang, XZ; Zhao, Q1
Bevans, S; Jun, J; Li, J; Nanayakkara, A; Polotsky, VY; Savransky, V; Smith, PL1
Abrams, GA; Andringa, KK; Bailey, SM; Darley-Usmar, VM; Doeller, JE; Eccleston, HB; King, AL; Kraus, DW; Mantena, SK; Vaughn, DP1
Angelini, DJ; Fan, C; Guggino, WB; Johns, RA; Li, Y; Liang, L; Su, Q1
Ashraf, QM; Delivoria-Papadopoulos, M; Mishra, OP3
Delivoria-Papadopoulos, M; Mishra, OP1
Bailey, DM; Berg, RM; Evans, KA; Hullin, DA; James, PE; Lundby, C; McCord, JM; McEneny, J; Möller, K; Pedersen, BK; Shore, A; Taudorf, S; Young, IS1
Abdelsaid, MA; Al-Shabrawey, M; El-Remessy, AB; Matragoon, S; Pillai, BA; Prakash, R1
Bird, CE; Chesler, NC; Marcus, NJ; Morgan, BJ; Olson, EB; Philippi, NR1
Del Rio, R; Iturriaga, R; Moya, EA1
Chovanec, M; Hampl, V; Herget, J; Novotná, J; Vízek, M; Wilhelm, J1
del Moral, ML; Molina, F; Peinado, MA; Rus, A1
Aronowski, J; Grotta, JC; Savitz, SI; Sharma, S; Xi, X; Yang, B1
Ducsay, CA; Myers, DA1
Jernigan, NL; Kanagy, NL; Norton, CE; Resta, TC; Walker, BR1
Ahmed, SB; Beaudin, AE; Foster, GE; Hanly, PJ; Pialoux, V; Poulin, MJ1
De La Cruz, JP; González-Correa, JA; Guerrero, A; López-Villodres, JA; Muñoz-Marin, J; Reyes, JJ1
Evans, LC; Liu, H; Pinkas, GA; Thompson, LP1
Bigam, DL; Cheung, PY; Lee, TF; Liu, JQ; Manouchehri, N; Yao, M1
Chiou, SH; Hung, MC; Hung, SC; Lee, YT; Lin, SP; Miller, SA; Wang, JY1
Hansen, DE; Kundumani-Sridharan, V; Rao, GN; Singh, NK1
Fung, ML; Lau, TY; Leung, TM; Liao, L; Liong, EC; Nanji, AA; Tipoe, GL; Xiao, J1
Beesley, PW; Bissoon, N; Gurd, JW; Nakazawa, T; Vannucci, SJ; Yamamoto, T1
Beckman, JS; Parks, DA; Teng, RJ; Ye, YZ1
Engelhardt, JF; Fan, C; Li, Q; Ross, D1
Bai, J; Hashimoto, N; Hattori, I; Kondo, N; Nakamura, H; Nozaki, K; Takagi, Y; Yodoi, J1
Bentura, ML; Castro-Blanco, S; Encinas, JM; Fernández, AP; Fernández-Vizarra, P; Rodrigo, J; Salas, E; Serrano, J1
Alonso, D; Castro-Blanco, S; Encinas, JM; Fernández, AP; Fernández-Vizarra, P; Gómez, MB; Martínez-Murillo, R; Ríos-Tejada, F; Rodrigo, J; Sánchez, J; Serrano, J1
Ackland-Berglund, C; Franciosi, JP; Guice, KS; Hillery, CA; Holzhauer, S; Kaul, S; Mohandas, N; Oldham, KT; Ou, J; Ou, Z; Pritchard, KA; Shi, Y; Signorino, P; Witte, K1
Bentura, ML; Castro-Blanco, S; Encinas, JM; Fernández, AP; Rodrigo, J; Serrano, J1
Asleh, R; Binah, O; Larisch, S; Levy, AP; Shilkrut, M; Yaniv, G1
Kundu, GC; Mahabeleshwar, GH1
Ashraf, QM; Delivoria-Papadopoulos, M; Fritz, KI; Mishra, OP; Zubrow, AB1
Das, R; Kundu, GC; Mahabeleshwar, GH1
Qiu, MH; Sun, FY; Zhang, R1
Castro-Blanco, S; Encinas, JM; Fernández, AP; Muñoz, P; Rodrigo, J; Salas, E; Serrano, J1
Fidler, IJ; Yokoi, K1
Bybee, KA; Otto, ME; Singh, RJ; Somers, VK; Svatikova, A; Wang, HH; Wolk, R1
Dekhuijzen, PN; Ennen, L; Heunks, LM; van der Heijden, HF; van Kuppevelt, TH; Versteeg, EM; Vina, J; Zhu, X1
Bolon, M; Ouellette, Y; Rose, K; Tyml, K1
Acs, G; Cohen, N; Dalgard, C; Lai, SY; Lu, H; Mohyeldin, A; Verma, A1
Avivi, A; Nevo, E; Shams, I1
Dekhuijzen, PN; Geraedts, MC; Heunks, LM; Ottenheijm, CA1
Banasová, A; Bíbová, J; Hampl, V; Herget, J; Hnilicková, O; Lachmanová, V; Miková, D; Uhlík, J1
Corley, KM; Lilly, B; Taylor, CJ1
Bini, L; Buonocore, G; Ciccoli, L; Leoncini, S; Marzocchi, B; Perrone, S; Rossi, V; Tani, C1
Chang, NS; Doherty, J; Ensign, A; Hong, Q; Hsu, LJ; Schultz, L1
Dahmani, S; Gressens, P; Mantz, J; Rouelle, D1
Burke, AS; Cox, RA; Enkhbaatar, P; Hawkins, HK; Jodoin, JM; Lee, S; Maybauer, DM; Maybauer, MO; Morita, N; Murakami, K; Rudloff, HE; Salsbury, JR; Schmalstieg, FC; Traber, DL; Traber, LD; Westphal, M; Westphal-Varghese, BB1
Conde, SV; Gonzalez, C; Monteiro, EC; Obeso, A; Rigual, R1
Encinas, JM; Fernández, AP; Martínez, A; Rodrigo, J; Serrano, J1
Korynta, J; Mahelková, G; Moravová, A; Novotná, J; Vytášek, R; Wilhelm, J1
Bainbridge, SA; Belkacemi, L; Dickinson, MA; Graham, CH; Smith, GN1
Chinta, S; Gao, Y; Liu, J; Negash, S; Raj, JU; Zhou, W1
Dayyat, E; Gozal, D; Kheirandish-Gozal, L; Sans Capdevila, O; Serpero, LD1
Andresen, JH; Escrig, R; Saugstad, OD; Solberg, R; Vento, M1
Basner, RC; Canfield, SM; Colombo, PC; Factor, P; Higgins, C; Jelic, S; Kawut, SM; LeJemtel, TH; Onat, D; Padeletti, M1
Hedner, T; Lundborg, P1
Carlsson, A; Dahlgren, N; Sakabe, T; Siesjö, BK1
MacMillan, V1
Cottet-Emard, JM; Dalmaz, Y; Pequignot, JM; Peyrin, L1
Hagar, H; Shah, SV; Ueda, N1
Acevedo, C; Ahmed, A; Dunk, C; Jiang, J; Khaliq, A; Li, XF; Shams, M; Weich, H; Whittle, M1
Corti, M; Dausman, JD; El-Dahr, SS; Gozal, D; Gozal, E; Simakajornboon, N; Xue, YD1
Bachschmid, M; Zou, MH1
Hirouchi, M; Itoh, Y; Oka, M; Ukai, Y1
Block, ER; Su, Y1
Demiryürek, AT; Kane, KA; Karamsetty, MR; MacLean, MR; McPhaden, AR; Wadsworth, RM1
Eghbali-Webb, M; Griffin, M; Lee, HW; Zhao, L1
Eis, AL; Myatt, L; Stanek, J1
Ashraf, QM; Delivoria-Papadopoulos, M; Mishra, OP; Zanelli, SA1
Burton, GJ; Hung, TH; Skepper, JN1
Alonso, D; Bentura, ML; Castro-Blanco, S; Encinas, JM; Fernández, AP; Fernández-Vizarra, P; Richart, A; Rodrigo, J; Rodríguez, I; Ruíz-Cabello, J; Santacana, M; Serrano, J; Uttenthal, LO1
Aust, G; Nieber, K; Schilling, N; Spanel-Borowski, K; Tscheudschilsuren, G1
Davis, JN2
Engel, J; Hedner, T; Lundborg, P2
Davalli, P; Guarnieri, C; Ligabue, A1
Lesch, M; Taegtmeyer, H1
Linklater, J; van Heyningen, R1
Fujiwara, M; Hamahata, K; Hasegawa, H; Hayashi, Y; Koshimura, K; Lee, K; Miwa, S; Watanabe, Y1
Freeman, GB; Gibson, GE; Nielsen, P1
Fujiwara, M; Lee, K; Miwa, S1
Gekeler, V; Probst, H; Scheffler, K; Schiffer, H1
Banderet, LE; Lieberman, HR1
Fidone, S; Gonzalez, C; Gonzalez, E; Rigual, R1
Milley, JR1
Cherian, G; Gero, T; Newberry, PD; Rohrer, JW1
Baumel, I; DeFeo, JJ; Lal, H; Schatz, R1
Cymerman, A; McCullough, D; Robinson, SM1
Trayhurn, P; Van Heyningen, R1
Carlsson, A; Davis, JN1
Krants, D; Meerson, FZ; Sadyraliev, TS1
Ainokenova, RR; Kaufman, OIa1
Pshennikova, MG1
Aĭnokenova, RR; Krants, D; Meerson, FZ; Sadyraliev, TS1
Volkov, MS1
Debijadji, R; Perović, L; Stosić, N; Varagić, V1
Demopoulos, HB; Duke, PS; Mitamura, A; Yuen, T1
Anthony, A; Nelson, BD1

Reviews

1 review(s) available for tyrosine and Hypoxia

ArticleYear
eNOS activation and NO function: differential control of steroidogenesis by nitric oxide and its adaptation with hypoxia.
    The Journal of endocrinology, 2011, Volume: 210, Issue:3

    Topics: Adrenal Glands; Animals; Cyclic GMP; Cysteine; Enzyme Activation; Female; Guanylate Cyclase; Heme; Humans; Hypoxia; Male; Models, Biological; Nitric Oxide; Nitric Oxide Synthase Type III; Ovary; Pregnancy; Protein Processing, Post-Translational; Steroids; Testis; Tyrosine

2011

Trials

6 trial(s) available for tyrosine and Hypoxia

ArticleYear
Moderate exercise blunts oxidative stress induced by normobaric hypoxic confinement.
    Medicine and science in sports and exercise, 2014, Volume: 46, Issue:1

    Topics: Adult; Advanced Oxidation Protein Products; Atmospheric Pressure; Catalase; Erythropoietin; Exercise; Exercise Test; Glutathione Peroxidase; Heart Rate; Humans; Hypoxia; Male; Malondialdehyde; Oxidative Stress; Oxygen; Physical Exertion; Superoxide Dismutase; Tyrosine; Young Adult

2014
Prooxidant/Antioxidant Balance in Hypoxia: A Cross-Over Study on Normobaric vs. Hypobaric "Live High-Train Low".
    PloS one, 2015, Volume: 10, Issue:9

    Topics: Adult; Advanced Oxidation Protein Products; Humans; Hypoxia; Male; Oxidative Stress; Physical Fitness; Superoxide Dismutase; Tyrosine; Uric Acid

2015
Losartan abolishes oxidative stress induced by intermittent hypoxia in humans.
    The Journal of physiology, 2011, Nov-15, Volume: 589, Issue:Pt 22

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Angiotensin II Type 1 Receptor Blockers; Cross-Over Studies; Deoxyguanosine; Double-Blind Method; Humans; Hypoxia; Losartan; Male; Nitric Oxide; Oxidative Stress; Tyrosine; Uric Acid

2011
Obstructive sleep apnea and endothelial function in school-aged nonobese children: effect of adenotonsillectomy.
    Circulation, 2007, Nov-13, Volume: 116, Issue:20

    Topics: Adenoidectomy; Arginine; Body Weight; CD40 Ligand; Child; Endothelium, Vascular; Female; Humans; Hyperemia; Hypoxia; Male; Nitric Oxide; Polysomnography; Sleep Apnea, Obstructive; Tonsillectomy; Tyrosine; Vasculitis

2007
Inflammation, oxidative stress, and repair capacity of the vascular endothelium in obstructive sleep apnea.
    Circulation, 2008, Apr-29, Volume: 117, Issue:17

    Topics: Adult; Biomarkers; Continuous Positive Airway Pressure; Cyclooxygenase 2; Endothelium, Vascular; Female; Humans; Hypoxia; Male; Middle Aged; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxidative Stress; Severity of Illness Index; Sleep Apnea, Obstructive; Treatment Outcome; Tyrosine; Vasculitis; Vasodilation; Veins

2008
Treatment with tyrosine, a neurotransmitter precursor, reduces environmental stress in humans.
    Brain research bulletin, 1989, Volume: 22, Issue:4

    Topics: Adolescent; Adult; Cognition Disorders; Cold Temperature; Double-Blind Method; Humans; Hypoxia; Male; Stress, Physiological; Tyrosine

1989

Other Studies

120 other study(ies) available for tyrosine and Hypoxia

ArticleYear
Urinary metabolic modulation in human participants residing in Siachen: a 1H NMR metabolomics approach.
    Scientific reports, 2022, 05-31, Volume: 12, Issue:1

    Topics: Altitude Sickness; Humans; Hypoxia; Metabolomics; Proton Magnetic Resonance Spectroscopy; Tyrosine

2022
Intermittent hypoxia mediated by TSP1 dependent on STAT3 induces cardiac fibroblast activation and cardiac fibrosis.
    eLife, 2020, 01-14, Volume: 9

    Topics: Animals; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Echocardiography; Fibroblasts; Fibrosis; Gene Expression Regulation; Gene Silencing; Heart; Humans; Hypoxia; Male; Mice; Mice, Inbred C57BL; Myocardium; Phosphorylation; Promoter Regions, Genetic; RNA, Small Interfering; Signal Transduction; STAT3 Transcription Factor; Thrombospondin 1; Tyrosine

2020
Enhanced NO-dependent pulmonary vasodilation limits increased vasoconstrictor sensitivity in neonatal chronic hypoxia.
    American journal of physiology. Heart and circulatory physiology, 2017, Oct-01, Volume: 313, Issue:4

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Animals, Newborn; Chronic Disease; Enzyme Inhibitors; Free Radical Scavengers; Hypoxia; Lung; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Pulmonary Circulation; Rats; Rats, Sprague-Dawley; Tyrosine; Vascular Resistance; Vasoconstriction; Vasoconstrictor Agents; Vasodilation

2017
Important role of endothelium-dependent hyperpolarization in the pulmonary microcirculation in male mice: implications for hypoxia-induced pulmonary hypertension.
    American journal of physiology. Heart and circulatory physiology, 2018, 05-01, Volume: 314, Issue:5

    Topics: Animals; Biological Factors; Disease Models, Animal; Endothelium, Vascular; Hypertension, Pulmonary; Hypoxia; Male; Membrane Potentials; Mice, Inbred C57BL; Microcirculation; Nitric Oxide; Pulmonary Artery; Pulmonary Circulation; Signal Transduction; Tyrosine; Vascular Remodeling; Vasodilation; Vasodilator Agents

2018
Nitration of MnSOD in the Carotid Body and Adrenal Gland Induced by Chronic Intermittent Hypoxia.
    The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 2018, Volume: 66, Issue:10

    Topics: Adrenal Glands; Animals; Carotid Body; Hypoxia; Immunohistochemistry; Male; Nitrosative Stress; Oxidative Stress; Rats, Sprague-Dawley; Superoxide Dismutase; Tyrosine

2018
High sucrose low copper diet in pregnant diabetic rats induces transient oxidative stress, hypoxia, and apoptosis in the offspring's liver.
    Birth defects research, 2018, 07-17, Volume: 110, Issue:12

    Topics: Animals; Antioxidants; Apoptosis; Biomarkers; Catalase; Cell Proliferation; Copper; Diabetes Mellitus, Experimental; Diet; Female; Hypoxia; Liver; Malondialdehyde; NF-kappa B; Oxidative Stress; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Sucrose; Superoxide Dismutase; Tyrosine; Weight Gain

2018
Selenoprotein T as a new positive inotrope in the goldfish,
    The Journal of experimental biology, 2019, 06-04, Volume: 222, Issue:Pt 11

    Topics: Animals; Cardiac Output; Endoplasmic Reticulum; Female; Fish Proteins; Goldfish; Heart; Hypoxia; Male; Myocardial Contraction; Myocardium; Selenoproteins; Tyrosine

2019
Sildenafil inhibits hypoxia-induced transient receptor potential canonical protein expression in pulmonary arterial smooth muscle via cGMP-PKG-PPARγ axis.
    American journal of respiratory cell and molecular biology, 2013, Volume: 49, Issue:2

    Topics: Animals; Benzamides; Benzophenones; Carbazoles; Cell Movement; Cell Proliferation; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Gene Expression Regulation; Hypoxia; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Phosphodiesterase 5 Inhibitors; Piperazines; PPAR gamma; Protein Kinase Inhibitors; Pulmonary Artery; Purines; Pyridines; Rats; Rats, Wistar; Signal Transduction; Sildenafil Citrate; Sulfones; TRPC Cation Channels; Tyrosine

2013
Oxidative stress augments pulmonary hypertension in chronically hypoxic mice overexpressing the oxidized LDL receptor.
    American journal of physiology. Heart and circulatory physiology, 2013, Jul-15, Volume: 305, Issue:2

    Topics: Animals; Antioxidants; Chronic Disease; Disease Models, Animal; Disease Progression; Enzyme Inhibitors; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia; Lipoproteins, LDL; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; NADPH Oxidases; Oxidative Stress; Pulmonary Artery; Reactive Oxygen Species; Scavenger Receptors, Class E; Signal Transduction; Tyrosine; Up-Regulation; Ventricular Function, Right; Ventricular Pressure

2013
Oxidative stress in breath-hold divers after repetitive dives.
    Diving and hyperbaric medicine, 2013, Volume: 43, Issue:2

    Topics: Adult; Biomarkers; Breath Holding; Diving; Humans; Hyperoxia; Hypoxia; Male; Nitric Oxide; Nitrites; Oxidative Stress; Sulfhydryl Compounds; Time Factors; Tyrosine

2013
Moderate hypoxia followed by reoxygenation results in blood-brain barrier breakdown via oxidative stress-dependent tight-junction protein disruption.
    PloS one, 2013, Volume: 8, Issue:12

    Topics: Animals; Blood-Brain Barrier; Cell Membrane; Claudin-5; Endothelial Cells; Guinea Pigs; Hypoxia; Microvessels; Mitochondria; Oxidative Stress; Permeability; Reactive Oxygen Species; Reperfusion Injury; Tight Junction Proteins; Tight Junctions; Tyrosine; Zonula Occludens-1 Protein

2013
Cyclin G2 promotes hypoxia-driven local invasion of glioblastoma by orchestrating cytoskeletal dynamics.
    Neoplasia (New York, N.Y.), 2013, Volume: 15, Issue:11

    Topics: Cell Line, Tumor; Cell Movement; Cyclin G2; Cytoskeleton; Glioblastoma; Humans; Hypoxia; Microfilament Proteins; Neoplasm Invasiveness; Phosphorylation; Protein Binding; Protein Structure, Tertiary; Tyrosine

2013
Deletion of metallothionein exacerbates intermittent hypoxia-induced oxidative and inflammatory injury in aorta.
    Oxidative medicine and cellular longevity, 2014, Volume: 2014

    Topics: Aldehydes; Animals; Aorta; Apoptosis; Connective Tissue Growth Factor; Hypoxia; Metallothionein; Mice; Mice, Knockout; NADPH Oxidases; Nitric Oxide Synthase Type III; Oxidative Stress; Time Factors; Tumor Necrosis Factor-alpha; Tyrosine

2014
Hypoxia- or PDGF-BB-dependent paxillin tyrosine phosphorylation in pulmonary hypertension is reversed by HIF-1α depletion or imatinib treatment.
    Thrombosis and haemostasis, 2014, Volume: 112, Issue:6

    Topics: Active Transport, Cell Nucleus; Animals; Antihypertensive Agents; Apoptosis; Becaplermin; Benzamides; Cell Adhesion; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Humans; Hypertension, Pulmonary; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Imatinib Mesylate; Mice, Inbred C57BL; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Paxillin; Phosphorylation; Piperazines; Proto-Oncogene Proteins c-sis; Pulmonary Artery; Pyrimidines; Receptor, Platelet-Derived Growth Factor beta; RNA Interference; Signal Transduction; Time Factors; Transfection; Tyrosine; Vascular Remodeling

2014
Tanshinone I inhibits tumor angiogenesis by reducing Stat3 phosphorylation at Tyr705 and hypoxia-induced HIF-1α accumulation in both endothelial and tumor cells.
    Oncotarget, 2015, Jun-30, Volume: 6, Issue:18

    Topics: Abietanes; Animals; Antineoplastic Agents, Phytogenic; Aorta; Apoptosis; Blotting, Western; Cell Movement; Cell Proliferation; Chickens; Chorioallantoic Membrane; Endothelium, Vascular; Enzyme-Linked Immunosorbent Assay; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Neoplasms; Neovascularization, Pathologic; Phosphorylation; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; STAT3 Transcription Factor; Tumor Cells, Cultured; Tyrosine

2015
Secreted tyrosine sulfated-eIF5A mediates oxidative stress-induced apoptosis.
    Scientific reports, 2015, Sep-08, Volume: 5

    Topics: Animals; Antibodies, Monoclonal; Antibodies, Neutralizing; Apoptosis; Disease Models, Animal; Eukaryotic Translation Initiation Factor 5A; Golgi Apparatus; Humans; Hypoxia; Male; Models, Biological; Myocardial Reperfusion Injury; Myocytes, Cardiac; Oxidative Stress; Oxygen; Peptide Fragments; Peptide Initiation Factors; Protein Transport; Rats; RNA-Binding Proteins; Signal Transduction; trans-Golgi Network; Tyrosine

2015
Effects of melatonin on the nitric oxide system and protein nitration in the hypobaric hypoxic rat hippocampus.
    BMC neuroscience, 2015, Oct-06, Volume: 16

    Topics: Altitude Sickness; Animals; Antioxidants; Caspase 3; Disease Models, Animal; Hippocampus; Hypoxia; Male; Melatonin; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Rats; Rats, Wistar; Tyrosine

2015
FemHab: The effects of bed rest and hypoxia on oxidative stress in healthy women.
    Journal of applied physiology (Bethesda, Md. : 1985), 2016, Apr-15, Volume: 120, Issue:8

    Topics: Adult; Antioxidants; Bed Rest; Biomarkers; Catalase; Female; Glutathione Peroxidase; Humans; Hypoxia; Malondialdehyde; Nitrites; Nitrogen Oxides; Oxidative Stress; Superoxide Dismutase; Tyrosine; Uric Acid; Women's Health

2016
Intermittent Hypoxia-Induced Carotid Body Chemosensory Potentiation and Hypertension Are Critically Dependent on Peroxynitrite Formation.
    Oxidative medicine and cellular longevity, 2016, Volume: 2016

    Topics: Animals; Azoles; Blood Pressure; Carotid Body; Diastole; Hypertension; Hypoxia; Isoindoles; Male; Neuronal Plasticity; Organoselenium Compounds; Peroxynitrous Acid; Rats, Sprague-Dawley; Systole; Tyrosine

2016
Nox4 contributes to the hypoxia-mediated regulation of actin cytoskeleton in cerebrovascular smooth muscle.
    Life sciences, 2016, Oct-15, Volume: 163

    Topics: Actin Cytoskeleton; Actins; Animals; Cells, Cultured; Humans; Hypoxia; Membrane Glycoproteins; Middle Cerebral Artery; Muscle, Smooth, Vascular; NADPH Oxidase 2; NADPH Oxidase 4; NADPH Oxidases; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Rats; Reperfusion Injury; RNA, Small Interfering; Tyrosine; Up-Regulation

2016
Oxidative stress augments chemoreflex sensitivity in rats exposed to chronic intermittent hypoxia.
    Respiratory physiology & neurobiology, 2016, Volume: 234

    Topics: Acetophenones; Allopurinol; Analysis of Variance; Animals; Anti-Arrhythmia Agents; Antioxidants; Body Weight; Carbon Dioxide; Carotid Sinus; Catecholamines; Chemoreceptor Cells; Free Radical Scavengers; Heart Rate; Hypoxia; Losartan; Male; Oxidative Stress; Oxygen Consumption; Plethysmography; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Regression Analysis; Respiration; Tidal Volume; Time Factors; Tyrosine

2016
1400W ameliorates acute hypobaric hypoxia/reoxygenation-induced cognitive deficits by suppressing the induction of inducible nitric oxide synthase in rat cerebral cortex microglia.
    Behavioural brain research, 2017, 02-15, Volume: 319

    Topics: Animals; Annexin A5; Apoptosis; Cells, Cultured; Cognition Disorders; Disease Models, Animal; Gene Expression Regulation; Hypoxia; Imines; Lipid Peroxidation; Malondialdehyde; Maze Learning; Microglia; Nerve Tissue Proteins; Nitric Oxide; Nitric Oxide Synthase Type II; Oxygen; Rats; Rats, Sprague-Dawley; Tyrosine

2017
Homocysteine ameliorates the endothelium-independent hypoxic vasoconstriction via the suppression of phosphatidylinositol 3-kinase/Akt pathway in porcine coronary arteries.
    Biochemical and biophysical research communications, 2017, 04-22, Volume: 486, Issue:1

    Topics: Animals; Blotting, Western; Class Ia Phosphatidylinositol 3-Kinase; Coronary Vessels; Dose-Response Relationship, Drug; Endothelium, Vascular; Homocysteine; Hypoxia; In Vitro Techniques; Myosin Light Chains; Phosphorylation; Protein Subunits; Proto-Oncogene Proteins c-akt; Serine; Signal Transduction; Swine; Time Factors; Tyrosine; Vasoconstriction

2017
Intermittent hypoxia has organ-specific effects on oxidative stress.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2008, Volume: 295, Issue:4

    Topics: Acetophenones; Animals; Body Weight; Eating; Enzyme Inhibitors; Erythrocytes; Glutathione; Glutathione Disulfide; Hypoxia; Lipid Peroxidation; Lipoproteins, LDL; Liver; Male; Malondialdehyde; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardium; NADPH Oxidases; Oxidative Stress; Phosphorylation; Superoxide Dismutase; Tyrosine

2008
High fat diet induces dysregulation of hepatic oxygen gradients and mitochondrial function in vivo.
    The Biochemical journal, 2009, Jan-01, Volume: 417, Issue:1

    Topics: Animals; Cell Respiration; Cytochrome P-450 CYP2E1; Dietary Fats; Fatty Liver; Hypoxia; Liver; Male; Membrane Potential, Mitochondrial; Mice; Mice, Inbred C57BL; Mitochondria, Liver; Mitochondrial Proteins; Nitric Oxide; Nitric Oxide Synthase Type II; Oxidative Stress; Tyrosine

2009
Hypoxia-induced mitogenic factor/FIZZ1 induces intracellular calcium release through the PLC-IP(3) pathway.
    American journal of physiology. Lung cellular and molecular physiology, 2009, Volume: 297, Issue:2

    Topics: Aniline Compounds; Calcium; Calcium Signaling; Estrenes; Fluorescent Dyes; Heterotrimeric GTP-Binding Proteins; Humans; Hypoxia; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Intercellular Signaling Peptides and Proteins; Muscle, Smooth, Vascular; Phosphodiesterase Inhibitors; Phosphorylation; Pulmonary Artery; Pyrrolidinones; Recombinant Proteins; RNA, Small Interfering; Type C Phospholipases; Tyrosine; Vasoconstriction; Xanthenes

2009
Tyrosine phosphorylation of neuronal nitric oxide synthase (nNOS) during hypoxia in the cerebral cortex of newborn piglets: the role of nitric oxide.
    Neuroscience letters, 2009, Oct-02, Volume: 462, Issue:1

    Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Blotting, Western; Cell Membrane; Cerebral Cortex; Densitometry; Electrophoresis, Polyacrylamide Gel; Hypoxia; Luminescence; Nitric Oxide; Nitric Oxide Synthase Type I; Phosphocreatine; Phosphorylation; Random Allocation; Swine; Tyrosine

2009
Mechanism of increased tyrosine (Tyr(99)) phosphorylation of calmodulin during hypoxia in the cerebral cortex of newborn piglets: the role of nNOS-derived nitric oxide.
    Neurochemical research, 2010, Volume: 35, Issue:1

    Topics: Animals; Animals, Newborn; Blotting, Western; Cerebral Cortex; Hypoxia; Nitric Oxide; Nitric Oxide Synthase Type I; Phosphorylation; Swine; Tyrosine

2010
Mechanism of post-translational modification by tyrosine phosphorylation of apoptotic proteins during hypoxia in the cerebral cortex of newborn piglets.
    Neurochemical research, 2010, Volume: 35, Issue:1

    Topics: Animals; Animals, Newborn; Apoptosis; Blotting, Western; Cerebral Cortex; Electrophoresis, Polyacrylamide Gel; Hypoxia; Phosphocreatine; Phosphorylation; Protein Processing, Post-Translational; Swine; Tyrosine

2010
Increased cerebral output of free radicals during hypoxia: implications for acute mountain sickness?
    American journal of physiology. Regulatory, integrative and comparative physiology, 2009, Volume: 297, Issue:5

    Topics: Acute Disease; Adult; Altitude Sickness; Biomarkers; Blood-Brain Barrier; Brain; Free Radicals; Headache; Health Surveys; Humans; Hypoxia; Male; Nerve Growth Factors; Oxidative Stress; Oxygen; Phosphopyruvate Hydratase; Regional Blood Flow; Retrospective Studies; Risk Factors; S100 Calcium Binding Protein beta Subunit; S100 Proteins; Tyrosine

2009
Early intervention of tyrosine nitration prevents vaso-obliteration and neovascularization in ischemic retinopathy.
    The Journal of pharmacology and experimental therapeutics, 2010, Volume: 332, Issue:1

    Topics: Acetylcysteine; Animals; Animals, Newborn; Apoptosis; Blotting, Western; Catechin; Cells, Cultured; Disease Models, Animal; Endothelial Cells; Glutathione; Hyperoxia; Hypoxia; Ischemia; Lipid Peroxidation; Metalloporphyrins; Mice; Mice, Inbred C57BL; Peroxynitrous Acid; Protective Agents; Retinal Neovascularization; Retinal Vessels; Tyrosine

2010
Time course of intermittent hypoxia-induced impairments in resistance artery structure and function.
    Respiratory physiology & neurobiology, 2010, Feb-28, Volume: 170, Issue:2

    Topics: Acetylcholine; Analysis of Variance; Animals; Arteries; Chronic Disease; Collagen; Endothelium, Vascular; Hypoxia; Immunohistochemistry; Isoprostanes; Male; Muscle, Skeletal; Nitric Oxide Donors; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Nitroprusside; Oxygen; Partial Pressure; Rats; Rats, Sprague-Dawley; Time Factors; Tyrosine; Vascular Resistance; Vasodilation; Vasodilator Agents

2010
Carotid body and cardiorespiratory alterations in intermittent hypoxia: the oxidative link.
    The European respiratory journal, 2010, Volume: 36, Issue:1

    Topics: Animals; Antioxidants; Ascorbic Acid; Carotid Body; Chemoreceptor Cells; Heart Rate; Hypertension; Hypoxia; Lipid Peroxidation; Lipids; Male; Malondialdehyde; Nitric Oxide Synthase Type II; Nitrosamines; Oxidative Stress; Pulmonary Ventilation; Rats; Sleep Apnea, Obstructive; Tyrosine

2010
Hypercapnia attenuates hypoxic pulmonary hypertension by inhibiting lung radical injury.
    Physiological research, 2009, Volume: 58 Suppl 2

    Topics: Animals; Blood Pressure; Chronic Disease; Disease Models, Animal; Hypercapnia; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Hypoxia; Lung Injury; Male; Oxidative Stress; Pulmonary Artery; Rats; Rats, Wistar; Time Factors; Tyrosine

2009
Endothelial NOS-derived nitric oxide prevents injury resulting from reoxygenation in the hypoxic lung.
    Free radical research, 2010, Volume: 44, Issue:9

    Topics: Animals; Cytoprotection; Enzyme Inhibitors; Hypoxia; In Situ Nick-End Labeling; Lung; Male; Nitric Oxide; Nitric Oxide Synthase Type III; Ornithine; Oxygen; Rats; Rats, Wistar; Reperfusion Injury; Thiobarbituric Acid Reactive Substances; Tyrosine

2010
IL-10 directly protects cortical neurons by activating PI-3 kinase and STAT-3 pathways.
    Brain research, 2011, Feb-10, Volume: 1373

    Topics: Analysis of Variance; Animals; Cell Death; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Drug Interactions; Embryo, Mammalian; Enzyme Inhibitors; Gene Expression Regulation; Glucose; Glutamic Acid; Hypoxia; Interleukin-10; Neurons; Neurotoxins; Phosphatidylinositol 3-Kinases; Phosphorylation; Rats; Rats, Sprague-Dawley; Receptors, Interleukin-18; RNA, Messenger; Signal Transduction; STAT3 Transcription Factor; Tetrazolium Salts; Thiazoles; Tyrosine

2011
Mechanism of CaM kinase IV activation during hypoxia in neuronal nuclei of the cerebral cortex of newborn piglets: the role of Src kinase.
    Neurochemical research, 2011, Volume: 36, Issue:8

    Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Calcium-Calmodulin-Dependent Protein Kinase Type 4; Calmodulin; Cerebral Cortex; Enzyme Activation; Hypoxia; Neurons; Phosphocreatine; src-Family Kinases; Swine; Tyrosine

2011
Intermittent hypoxia augments pulmonary vascular smooth muscle reactivity to NO: regulation by reactive oxygen species.
    Journal of applied physiology (Bethesda, Md. : 1985), 2011, Volume: 111, Issue:4

    Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Animals; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Endothelium-Dependent Relaxing Factors; Free Radical Scavengers; Hypertrophy, Right Ventricular; Hypocapnia; Hypoxia; Ionomycin; Lung; Male; Muscle, Smooth, Vascular; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type III; Polycythemia; Pulmonary Artery; Rats; Rats, Wistar; Reactive Oxygen Species; S-Nitroso-N-Acetylpenicillamine; Superoxides; Tyrosine; Vasodilation

2011
Cytoprotective effect of nonsteroidal antiinflammatory drugs in rat brain slices subjected to reoxygenation after oxygen-glucose deprivation.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2012, Apr-11, Volume: 45, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Brain; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cytoprotection; Dinoprostone; Glucose; Hypoxia; Interleukin-10; Interleukin-1beta; L-Lactate Dehydrogenase; Lipid Peroxidation; Lipid Peroxides; Male; Neuroprotective Agents; Nitrites; Nitrosation; Oxidative Stress; Oxygen; Rats; Rats, Wistar; Tyrosine

2012
Chronic hypoxia increases peroxynitrite, MMP9 expression, and collagen accumulation in fetal guinea pig hearts.
    Pediatric research, 2012, Volume: 71, Issue:1

    Topics: Acetylcysteine; Animals; Body Weight; Collagen; Female; Fetal Heart; Guinea Pigs; Hypoxia; Lipid Peroxidation; Matrix Metalloproteinase 9; Nitric Oxide Synthase Type II; Organ Size; Peroxynitrous Acid; Pregnancy; Tyrosine

2012
Infusing sodium bicarbonate suppresses hydrogen peroxide accumulation and superoxide dismutase activity in hypoxic-reoxygenated newborn piglets.
    PloS one, 2012, Volume: 7, Issue:6

    Topics: Acid-Base Equilibrium; Acidosis; Animals; Animals, Newborn; Blood Gas Analysis; Catalase; Cerebral Cortex; Disease Models, Animal; Female; Glutathione; Hemodynamics; Hydrogen Peroxide; Hypoxia; Infusions, Intravenous; Lactic Acid; Male; Oxidation-Reduction; Oxidative Stress; Oxygen; Pulmonary Alveoli; Resuscitation; Sodium Bicarbonate; Superoxide Dismutase; Swine; Tyrosine

2012
Survival of cancer stem cells under hypoxia and serum depletion via decrease in PP2A activity and activation of p38-MAPKAPK2-Hsp27.
    PloS one, 2012, Volume: 7, Issue:11

    Topics: AC133 Antigen; Animals; Antigens, CD; Apoptosis; Caspase 3; Caspase 9; Cell Line, Tumor; Cell Movement; Cell Survival; Gene Expression Regulation, Neoplastic; Glycoproteins; HSP27 Heat-Shock Proteins; Humans; Hypoxia; Intracellular Signaling Peptides and Proteins; Mice; Mice, SCID; Neoplasm Invasiveness; Neoplastic Stem Cells; p38 Mitogen-Activated Protein Kinases; Peptides; Protein Phosphatase 2; Protein Serine-Threonine Kinases; Signal Transduction; Tyrosine

2012
Both Kdr and Flt1 play a vital role in hypoxia-induced Src-PLD1-PKCγ-cPLA(2) activation and retinal neovascularization.
    Blood, 2013, Mar-07, Volume: 121, Issue:10

    Topics: Animals; Blotting, Western; Cell Movement; Cells, Cultured; DNA Replication; Endothelium, Vascular; Female; Fluorescent Antibody Technique; Group IV Phospholipases A2; Humans; Hypoxia; Mice; Mice, Inbred C57BL; Phospholipase D; Phosphorylation; Protein Kinase C; Proto-Oncogene Proteins pp60(c-src); Retinal Neovascularization; RNA, Small Interfering; Tyrosine; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor B; Vascular Endothelial Growth Factor Receptor-1; Vascular Endothelial Growth Factor Receptor-2

2013
Hepatic response to chronic hypoxia in experimental rat model through HIF-1 alpha, activator protein-1 and NF-kappa B.
    Histology and histopathology, 2013, Volume: 28, Issue:4

    Topics: Alanine Transaminase; Animals; Biomarkers; Blotting, Western; Chronic Disease; Dinoprost; Disease Models, Animal; Electrophoretic Mobility Shift Assay; Endothelin-1; Gene Expression Regulation; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Liver; Male; NF-kappa B; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors; Transcription Factor AP-1; Tyrosine; Vascular Endothelial Growth Factor A

2013
Differential effects of hypoxia-ischemia on subunit expression and tyrosine phosphorylation of the NMDA receptor in 7- and 21-day-old rats.
    Journal of neurochemistry, 2002, Volume: 82, Issue:4

    Topics: Age Factors; Animals; Carotid Arteries; Disease Models, Animal; Hypoxia; Hypoxia-Ischemia, Brain; Immunoblotting; Ligation; Nerve Tissue Proteins; Phosphorylation; Prosencephalon; Protein Subunits; Rats; Rats, Wistar; Receptors, N-Methyl-D-Aspartate; Tyrosine

2002
Urate produced during hypoxia protects heart proteins from peroxynitrite-mediated protein nitration.
    Free radical biology & medicine, 2002, Nov-01, Volume: 33, Issue:9

    Topics: Animals; Ascorbic Acid; Brain; Heart; Hypoxanthine; Hypoxia; In Vitro Techniques; Myocardium; Nitric Oxide; Nitrosation; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley; Tyrosine; Urate Oxidase; Uric Acid; Xanthine Dehydrogenase; Xanthine Oxidase

2002
Tyrosine phosphorylation of I kappa B alpha activates NF kappa B through a redox-regulated and c-Src-dependent mechanism following hypoxia/reoxygenation.
    The Journal of biological chemistry, 2003, Jan-17, Volume: 278, Issue:3

    Topics: Hypoxia; I-kappa B Proteins; NF-kappa B; NF-KappaB Inhibitor alpha; Phosphorylation; Proto-Oncogene Proteins pp60(c-src); Transcriptional Activation; Tyrosine

2003
Hypoxia-ischemia induces thioredoxin expression and nitrotyrosine formation in new-born rat brain.
    Redox report : communications in free radical research, 2002, Volume: 7, Issue:5

    Topics: Animals; Animals, Newborn; Blotting, Northern; Brain; Hypoxia; Models, Anatomic; Oxidants; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley; Reperfusion Injury; RNA, Messenger; Thioredoxins; Time Factors; Tyrosine

2002
Hypobaric hypoxia modifies constitutive nitric oxide synthase activity and protein nitration in the rat cerebellum.
    Brain research, 2003, Jun-20, Volume: 976, Issue:1

    Topics: Altitude; Animals; Cerebellum; Endothelium, Vascular; Hypoxia; Immunohistochemistry; Male; Nerve Tissue Proteins; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Rats; Rats, Wistar; Tyrosine

2003
Expression of nitrergic system and protein nitration in adult rat brains submitted to acute hypobaric hypoxia.
    Nitric oxide : biology and chemistry, 2003, Volume: 8, Issue:3

    Topics: Animals; Atmospheric Pressure; Brain Chemistry; Cerebral Cortex; Hypoxia; Immunohistochemistry; Male; Nitrergic Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Proteins; Rats; Rats, Wistar; Tyrosine

2003
Hypoxia-induced acute lung injury in murine models of sickle cell disease.
    American journal of physiology. Lung cellular and molecular physiology, 2004, Volume: 286, Issue:4

    Topics: Acute Disease; Anemia, Sickle Cell; Animals; Disease Models, Animal; Hemoglobin, Sickle; HSP90 Heat-Shock Proteins; Humans; Hypoxia; Lung Diseases; Mice; Mice, Inbred C57BL; Mice, Transgenic; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Tyrosine

2004
Nitric oxide system and protein nitration are modified by an acute hypobaric hypoxia in the adult rat hippocampus.
    Journal of neuropathology and experimental neurology, 2003, Volume: 62, Issue:8

    Topics: Animals; Blotting, Western; Cell Count; Disease Models, Animal; Endothelium, Vascular; Glial Fibrillary Acidic Protein; Hippocampus; Hypoxia; Immunohistochemistry; Male; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Rats; Rats, Wistar; Time Factors; Tyrosine

2003
Tyrosine kinases inhibitors block Fas-mediated deleterious effects in normoxic and hypoxic ventricular myocytes.
    Journal of molecular and cellular cardiology, 2003, Volume: 35, Issue:10

    Topics: Animals; Apoptosis; Calcium; Cells, Cultured; Electrophysiology; fas Receptor; Heart Ventricles; Hypoxia; Inositol 1,4,5-Trisphosphate; Ions; Mice; Muscle Cells; Myocytes, Cardiac; Oxygen; Phosphorylation; Protein-Tyrosine Kinases; Rats; Rats, Sprague-Dawley; Signal Transduction; Type C Phospholipases; Tyrosine

2003
Tyrosine kinase p56lck regulates cell motility and nuclear factor kappaB-mediated secretion of urokinase type plasminogen activator through tyrosine phosphorylation of IkappaBalpha following hypoxia/reoxygenation.
    The Journal of biological chemistry, 2003, Dec-26, Volume: 278, Issue:52

    Topics: Active Transport, Cell Nucleus; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Cell Nucleus; DNA, Complementary; Enzyme Inhibitors; Genes, Reporter; Humans; Hydrogen Peroxide; Hypoxia; I-kappa B Proteins; Luciferases; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); Microscopy, Fluorescence; Models, Biological; Mutation; NF-kappa B; NF-KappaB Inhibitor alpha; Oxidation-Reduction; Oxygen; Phosphorylation; Plasmids; Precipitin Tests; Promoter Regions, Genetic; Protein Binding; Serine; Signal Transduction; Time Factors; Transfection; Tyrosine; Urokinase-Type Plasminogen Activator; Vanadates

2003
Expression of phosphorylation of N-methyl-D-aspartate receptor subunits during graded hypoxia in the cerebral cortex of newborn piglets.
    Biology of the neonate, 2004, Volume: 85, Issue:2

    Topics: Animals; Animals, Newborn; Cerebral Cortex; Hypoxia; Phosphocreatine; Phosphorylation; Receptors, N-Methyl-D-Aspartate; Serine; Swine; Threonine; Tyrosine

2004
Tyrosine kinase, p56lck-induced cell motility, and urokinase-type plasminogen activator secretion involve activation of epidermal growth factor receptor/extracellular signal regulated kinase pathways.
    The Journal of biological chemistry, 2004, Mar-12, Volume: 279, Issue:11

    Topics: Blotting, Western; Cell Line, Tumor; Cell Movement; DNA, Complementary; Genes, Dominant; Humans; Hypoxia; Lymphocyte Specific Protein Tyrosine Kinase p56(lck); MAP Kinase Kinase 1; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Models, Biological; Mutation; Neoplasm Invasiveness; Phosphorylation; Plasmids; Precipitin Tests; Protein-Tyrosine Kinases; Signal Transduction; Time Factors; Transfection; Tyrosine; Urokinase-Type Plasminogen Activator

2004
Enhancement of ischemia-induced tyrosine phosphorylation of Kv1.2 by vascular endothelial growth factor via activation of phosphatidylinositol 3-kinase.
    Journal of neurochemistry, 2003, Volume: 87, Issue:6

    Topics: Animals; Blotting, Western; Cell Death; Cell Line, Tumor; Cell Survival; Cerebral Cortex; Drug Interactions; Enzyme Activation; Glial Fibrillary Acidic Protein; Glucose; Humans; Hypoxia; Hypoxia-Ischemia, Brain; Immunohistochemistry; In Vitro Techniques; Infarction, Middle Cerebral Artery; Kv1.2 Potassium Channel; Leukocyte Common Antigens; Male; Oligodeoxyribonucleotides, Antisense; Phosphatidylinositol 3-Kinases; Phosphopyruvate Hydratase; Phosphorylation; Potassium Channels; Potassium Channels, Voltage-Gated; Precipitin Tests; Propidium; Rats; Time Factors; Tyrosine; Vascular Endothelial Growth Factor A

2003
Nitric oxide synthase and NADPH-diaphorase after acute hypobaric hypoxia in the rat caudate putamen.
    Experimental neurology, 2004, Volume: 186, Issue:1

    Topics: Altitude; Animals; Blood Vessels; Blotting, Western; Cell Count; Endothelium; Hypoxia; Immunohistochemistry; Male; NADPH Dehydrogenase; Neostriatum; Neurons; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Rats; Rats, Wistar; Time Factors; Tyrosine

2004
Hypoxia increases resistance of human pancreatic cancer cells to apoptosis induced by gemcitabine.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Apr-01, Volume: 10, Issue:7

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Apoptosis; Blotting, Western; Butadienes; Cell Division; Cell Line, Tumor; Chromones; Deoxycytidine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Gemcitabine; Humans; Hypoxia; Mitogen-Activated Protein Kinases; Morpholines; Neovascularization, Pathologic; NF-kappa B; Nitriles; Oxygen; Pancreatic Neoplasms; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein-Tyrosine Kinases; Pyrimidines; Pyrroles; Signal Transduction; Sp1 Transcription Factor; Time Factors; Tyrosine

2004
Circulating free nitrotyrosine in obstructive sleep apnea.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2004, Volume: 287, Issue:2

    Topics: Adult; Chromatography, Liquid; Humans; Hypoxia; Male; Mass Spectrometry; Middle Aged; Nitric Oxide; Sleep; Sleep Apnea, Obstructive; Tyrosine

2004
Hypoxia-induced dysfunction of rat diaphragm: role of peroxynitrite.
    American journal of physiology. Lung cellular and molecular physiology, 2005, Volume: 288, Issue:1

    Topics: Animals; Azoles; Diaphragm; Enzyme Inhibitors; Hypoxia; In Vitro Techniques; Isoindoles; Lipid Peroxidation; Male; Muscle Contraction; Muscle Fatigue; omega-N-Methylarginine; Organoselenium Compounds; Peroxynitrous Acid; Rats; Rats, Wistar; Tyrosine

2005
Hypoxia/reoxygenation reduces microvascular endothelial cell coupling by a tyrosine and MAP kinase dependent pathway.
    Journal of cellular physiology, 2005, Volume: 204, Issue:1

    Topics: Adenosine Triphosphate; Animals; Cells, Cultured; Connexin 43; Electric Conductivity; Endothelial Cells; Enzyme Inhibitors; Hypoxia; Lactic Acid; Male; MAP Kinase Signaling System; Membrane Potentials; Microcirculation; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Phosphorylation; Protein-Tyrosine Kinases; Rats; Rats, Wistar; Reperfusion Injury; Sodium Cyanide; Tyrosine

2005
Erythropoietin signaling promotes invasiveness of human head and neck squamous cell carcinoma.
    Neoplasia (New York, N.Y.), 2005, Volume: 7, Issue:5

    Topics: Biopsy; Blotting, Western; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Movement; Collagen; Dose-Response Relationship, Drug; Drug Combinations; Erythropoietin; Gene Expression Regulation; Head and Neck Neoplasms; Humans; Hypoxia; Immunohistochemistry; Immunoprecipitation; Janus Kinase 2; Laminin; Models, Statistical; Neoplasm Invasiveness; Phosphorylation; Protein-Tyrosine Kinases; Proteoglycans; Proto-Oncogene Proteins; Receptors, Erythropoietin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Tyrosine

2005
Erythropoietin receptor spliced forms differentially expressed in blind subterranean mole rats.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2005, Volume: 19, Issue:12

    Topics: Alternative Splicing; Amino Acid Sequence; Animals; Bone Marrow; Cloning, Molecular; DNA, Complementary; Erythropoietin; Gene Expression Regulation; Hypoxia; Mole Rats; Molecular Sequence Data; Oxygen; Phosphorylation; Plasmids; Rats; Receptors, Erythropoietin; RNA; RNA, Messenger; Sequence Homology, Amino Acid; Signal Transduction; Species Specificity; Spleen; Tyrosine

2005
Hypoxia-induced skeletal muscle fiber dysfunction: role for reactive nitrogen species.
    American journal of physiology. Lung cellular and molecular physiology, 2006, Volume: 290, Issue:1

    Topics: Animals; Enzyme Inhibitors; Hyperoxia; Hypoxia; In Vitro Techniques; Kinetics; Male; Muscle Contraction; Muscle Fibers, Skeletal; Muscle, Skeletal; omega-N-Methylarginine; Oxygen; Partial Pressure; Rats; Rats, Wistar; Reactive Oxygen Species; Tyrosine

2006
Pulmonary vascular iNOS induction participates in the onset of chronic hypoxic pulmonary hypertension.
    American journal of physiology. Lung cellular and molecular physiology, 2006, Volume: 290, Issue:1

    Topics: Administration, Oral; Animals; Chronic Disease; Dose-Response Relationship, Drug; Enzyme Inhibitors; Exhalation; Hypertension, Pulmonary; Hypoxia; Lung; Lysine; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type II; Pulmonary Artery; Rats; Rats, Wistar; Time Factors; Tyrosine

2006
Hypoxia-inducible factor 1alpha modulates adhesion, migration, and FAK phosphorylation in vascular smooth muscle cells.
    Journal of cellular biochemistry, 2005, Dec-01, Volume: 96, Issue:5

    Topics: Adenoviridae; Animals; Aorta; Blotting, Western; Cattle; Cell Adhesion; Cell Movement; Cells, Cultured; Cobalt; DNA, Complementary; Endothelium, Vascular; Focal Adhesion Protein-Tyrosine Kinases; Humans; Hypoxia; Hypoxia-Inducible Factor 1, alpha Subunit; Immunoblotting; Immunoprecipitation; Luciferases; Microscopy, Fluorescence; Muscle, Smooth; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Neovascularization, Pathologic; Phosphorylation; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors; Transfection; Tyrosine; Vascular Endothelial Growth Factor A; Wound Healing

2005
Hypoxia-induced post-translational changes in red blood cell protein map of newborns.
    Pediatric research, 2005, Volume: 58, Issue:4

    Topics: Electrophoresis, Gel, Two-Dimensional; Electrophoresis, Polyacrylamide Gel; Erythrocytes; Humans; Hypoxia; Image Processing, Computer-Assisted; Immunoblotting; In Vitro Techniques; Infant, Newborn; Methemoglobin; Oxidative Stress; Oxygen; Phosphorylation; Phosphotyrosine; Protein Processing, Post-Translational; Silver Staining; Time Factors; Tyrosine; Umbilical Veins

2005
WOX1 is essential for tumor necrosis factor-, UV light-, staurosporine-, and p53-mediated cell death, and its tyrosine 33-phosphorylated form binds and stabilizes serine 46-phosphorylated p53.
    The Journal of biological chemistry, 2005, Dec-30, Volume: 280, Issue:52

    Topics: Active Transport, Cell Nucleus; Animals; Anisomycin; Cell Line, Tumor; Cell Nucleus; Cytoplasm; Cytosol; DNA, Complementary; Dose-Response Relationship, Drug; Etoposide; Fibroblasts; Genes, Dominant; Humans; Hypoxia; Imidazoles; Immunoprecipitation; Luminescent Proteins; Mice; Microscopy, Fluorescence; Models, Biological; Oxidoreductases; Phosphorylation; Piperazines; Proteasome Endopeptidase Complex; Protein Binding; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serine; Staurosporine; Time Factors; Tumor Necrosis Factor-alpha; Tumor Suppressor Protein p53; Tumor Suppressor Proteins; Two-Hybrid System Techniques; Tyrosine; U937 Cells; Ultraviolet Rays; WW Domain-Containing Oxidoreductase

2005
Effects of dexmedetomidine on hippocampal focal adhesion kinase tyrosine phosphorylation in physiologic and ischemic conditions.
    Anesthesiology, 2005, Volume: 103, Issue:5

    Topics: Adrenergic alpha-Agonists; Animals; Blotting, Western; Brain Ischemia; Caspase 3; Caspase Inhibitors; Cell Count; Cell Death; Cyclic AMP-Dependent Protein Kinases; Dexmedetomidine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Focal Adhesion Protein-Tyrosine Kinases; Glucose; Hippocampus; Hydrogen-Ion Concentration; Hypnotics and Sedatives; Hypoxia; Ischemic Preconditioning; Male; Phosphorylation; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha-2; Tyrosine

2005
Combined burn and smoke inhalation injury impairs ovine hypoxic pulmonary vasoconstriction.
    Critical care medicine, 2006, Volume: 34, Issue:5

    Topics: Animals; Burns; Female; Hypoxia; Lung; Multiple Trauma; Nitric Oxide Synthase Type II; Peroxynitrous Acid; Pulmonary Gas Exchange; Random Allocation; Respiratory Distress Syndrome; Sheep; Single-Blind Method; Smoke Inhalation Injury; Survival Analysis; Tyrosine; Vasoconstriction

2006
Function of the rat carotid body chemoreceptors in ageing.
    Journal of neurochemistry, 2006, Volume: 99, Issue:3

    Topics: Acidosis; Aging; Animals; Carotid Body; Catecholamines; Catechols; Chemoreceptor Cells; Female; Hypercapnia; Hypoxia; Male; Potassium; Rats; Rats, Sprague-Dawley; Seasons; Tyrosine; Tyrosine 3-Monooxygenase

2006
Effects of acute hypobaric hypoxia on the nitric oxide system of the rat cerebral cortex: Protective role of nitric oxide inhibitors.
    Neuroscience, 2006, Oct-27, Volume: 142, Issue:3

    Topics: Altitude; Analysis of Variance; Animals; Blotting, Western; Calcium; Cerebral Cortex; Disease Models, Animal; Enzyme Inhibitors; Hypoxia; Immunohistochemistry; Indazoles; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rats; Rats, Wistar; Time Factors; Tyrosine

2006
Changes of extracellular matrix of rat cornea after exposure to hypoxia.
    Physiological research, 2008, Volume: 57, Issue:1

    Topics: Analysis of Variance; Animals; Collagen; Cornea; Corneal Neovascularization; Extracellular Matrix; Eye Proteins; Free Radicals; Hypoxia; Male; Matrix Metalloproteinases; Oxidative Stress; Rats; Rats, Wistar; Time Factors; Tyrosine

2008
Glyceryl trinitrate inhibits hypoxia/reoxygenation-induced apoptosis in the syncytiotrophoblast of the human placenta: therapeutic implications for preeclampsia.
    The American journal of pathology, 2007, Volume: 170, Issue:3

    Topics: Aldehydes; Apoptosis; Blotting, Western; Caspase 3; Collagen Type XI; Female; Humans; Hypoxia; Immunohistochemistry; In Situ Nick-End Labeling; Microscopy, Electron, Transmission; Nitroglycerin; Organ Culture Techniques; Pre-Eclampsia; Pregnancy; Reperfusion Injury; Tocolytic Agents; Trophoblasts; Tyrosine

2007
Regulation of cGMP-dependent protein kinase-mediated vasodilation by hypoxia-induced reactive species in ovine fetal pulmonary veins.
    American journal of physiology. Lung cellular and molecular physiology, 2007, Volume: 293, Issue:4

    Topics: Animals; Cyclic GMP-Dependent Protein Kinase Type I; Cyclic GMP-Dependent Protein Kinases; Dose-Response Relationship, Drug; Fetus; Hypoxia; Isoenzymes; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Nitrates; Nitrites; Peroxynitrous Acid; Pulmonary Veins; Reactive Nitrogen Species; Reactive Oxygen Species; Sheep; Time Factors; Tyrosine; Vasodilation

2007
Resuscitation of hypoxic newborn piglets with oxygen induces a dose-dependent increase in markers of oxidation.
    Pediatric research, 2007, Volume: 62, Issue:5

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Animals, Newborn; Biomarkers; Chromatography, High Pressure Liquid; Deoxyguanosine; Disease Models, Animal; DNA Damage; Dose-Response Relationship, Drug; Female; Hypoxia; Male; Oxidative Stress; Oxygen; Oxygen Inhalation Therapy; Phenylalanine; Reactive Oxygen Species; Respiration, Artificial; Swine; Tandem Mass Spectrometry; Time Factors; Tyrosine

2007
Catecholamine metabolism in neonatal rat brain during asphyxia and recovery.
    Acta physiologica Scandinavica, 1980, Volume: 109, Issue:2

    Topics: Animals; Animals, Newborn; Asphyxia; Brain; Brain Stem; Catecholamines; Diencephalon; Dihydroxyphenylalanine; Dopamine; Hippocampus; Hypoxia; Norepinephrine; Rats; Time Factors; Tyrosine; Visual Cortex

1980
Effect of diazepam on cerebral monoamine synthesis during hypoxia and hypercapnia in the rat.
    Acta physiologica Scandinavica, 1982, Volume: 115, Issue:1

    Topics: 5-Hydroxytryptophan; Amino Acids; Animals; Brain; Cerebrovascular Circulation; Diazepam; Dihydroxyphenylalanine; Hypercapnia; Hypoxia; Male; Oxygen Consumption; Rats; Rats, Inbred Strains; Tryptophan; Tyrosine

1982
Cerebral monoamine and energy metabolism during recovery from hypoxia-oligemia.
    Canadian journal of physiology and pharmacology, 1980, Volume: 58, Issue:2

    Topics: Adenine Nucleotides; Animals; Blood Volume; Brain; Carbohydrate Metabolism; Energy Metabolism; Hydroxylation; Hypoxia; Male; Rats; Time Factors; Tryptophan; Tyrosine

1980
Adrenal response to long-term hypoxia is still increased after carotid body denervation in rat.
    Journal of applied physiology (Bethesda, Md. : 1985), 1994, Volume: 76, Issue:3

    Topics: Adrenal Glands; alpha-Methyltyrosine; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Carotid Body; Denervation; Dihydroxyphenylalanine; Dopamine; Epinephrine; Hydrazines; Hypoxia; Male; Methyltyrosines; Norepinephrine; Rats; Rats, Sprague-Dawley; Tyrosine; Tyrosine 3-Monooxygenase

1994
Tyrosine phosphorylation in DNA damage and cell death in hypoxic injury to LLC-PK1 cells.
    Kidney international, 1997, Volume: 51, Issue:6

    Topics: Animals; Benzoquinones; Cell Death; DNA Damage; Enzyme Inhibitors; Hypoxia; Lactams, Macrocyclic; LLC-PK1 Cells; Phenols; Phosphorylation; Protein-Tyrosine Kinases; Quinones; Rifabutin; Swine; Tyrosine

1997
Hypoxia down-regulates placenta growth factor, whereas fetal growth restriction up-regulates placenta growth factor expression: molecular evidence for "placental hyperoxia" in intrauterine growth restriction.
    Laboratory investigation; a journal of technical methods and pathology, 1999, Volume: 79, Issue:2

    Topics: Cell Line; Endothelial Growth Factors; Extraembryonic Membranes; Female; Fetal Growth Retardation; Humans; Hyperoxia; Hypoxia; In Vitro Techniques; Lymphokines; Nitric Oxide; Oxygen; Phosphorylation; Placenta; Placenta Growth Factor; Pregnancy; Pregnancy Proteins; Receptor Protein-Tyrosine Kinases; Receptors, Growth Factor; Receptors, Vascular Endothelial Growth Factor; RNA, Messenger; Tissue Distribution; Trophoblasts; Tyrosine; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors

1999
Hypoxia induces selective SAPK/JNK-2-AP-1 pathway activation in the nucleus tractus solitarii of the conscious rat.
    Journal of neurochemistry, 1999, Volume: 73, Issue:2

    Topics: Adaptor Protein Complex alpha Subunits; Adaptor Proteins, Vesicular Transport; Animals; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Consciousness; DNA-Binding Proteins; Hypoxia; Hypoxia, Brain; Male; Membrane Proteins; Mitogen-Activated Protein Kinase 9; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Binding; Protein Kinases; Rats; Rats, Sprague-Dawley; Respiration; Signal Transduction; Solitary Nucleus; Transcription Factors; Tyrosine

1999
Hypoxia-reoxygenation triggers coronary vasospasm in isolated bovine coronary arteries via tyrosine nitration of prostacyclin synthase.
    The Journal of experimental medicine, 1999, Jul-05, Volume: 190, Issue:1

    Topics: Angiotensin II; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bridged Bicyclo Compounds, Heterocyclic; Cattle; Coronary Vasospasm; Cytochrome P-450 Enzyme System; Fatty Acids, Unsaturated; Hydrazines; Hypoxia; In Vitro Techniques; Indomethacin; Intramolecular Oxidoreductases; Nitrates; Oxygen; Tyrosine

1999
Involvement of peroxynitrite and hydroxyradical generated from nitric oxide in hypoxia/reoxygenation injury in rat cerebrocortical slices.
    Neuropharmacology, 2000, Apr-27, Volume: 39, Issue:7

    Topics: Adenosine Triphosphate; Animals; Cell-Free System; Cerebral Cortex; Cyclic AMP; Enzyme Inhibitors; Hydroxyl Radical; Hypoxia; Male; Neurons; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxidants; Poly(ADP-ribose) Polymerase Inhibitors; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Salicylates; Tyrosine

2000
Role of calpain in hypoxic inhibition of nitric oxide synthase activity in pulmonary endothelial cells.
    American journal of physiology. Lung cellular and molecular physiology, 2000, Volume: 278, Issue:6

    Topics: Animals; Calpain; Caveolin 1; Caveolins; Cells, Cultured; Cysteine Proteinase Inhibitors; Dipeptides; Endothelium, Vascular; HSP90 Heat-Shock Proteins; Hypoxia; Membrane Proteins; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Phosphorylation; Pulmonary Artery; Serine; Swine; Tyrosine

2000
Accumulation of nitrotyrosine correlates with endothelial NO synthase in pulmonary resistance arteries during chronic hypoxia in the rat.
    Pulmonary pharmacology & therapeutics, 2000, Volume: 13, Issue:4

    Topics: Actins; Animals; Arteries; Endothelium; Hypertrophy, Right Ventricular; Hypoxia; Immunohistochemistry; Lung; Nitric Oxide Synthase; Rats; Tyrosine; Vascular Resistance

2000
Gender-related differences in proliferative response of cardiac fibroblasts to hypoxia: effects of estrogen.
    Molecular and cellular biochemistry, 2000, Volume: 215, Issue:1-2

    Topics: Age Factors; Animals; Blotting, Western; Cell Division; Cell Nucleus; Cells, Cultured; Cyclin B; Cyclin B1; Cyclin D1; Cytoplasm; Cytosol; DNA; Enzyme Activation; Enzyme Inhibitors; Estradiol; Estrogen Antagonists; Estrogen Receptor beta; Female; Fibroblasts; Fulvestrant; Genistein; Hypoxia; Male; Myocardium; Phosphorylation; Precipitin Tests; Proliferating Cell Nuclear Antigen; Protein Binding; Protein-Tyrosine Kinases; Rats; Rats, Inbred F344; Receptors, Estrogen; Response Elements; Sex Factors; Tyrosine

2000
Nitrotyrosine immunostaining correlates with increased extracellular matrix: evidence of postplacental hypoxia.
    Placenta, 2001, Volume: 22 Suppl A

    Topics: Adult; Diabetes Mellitus, Type 1; Embolism, Amniotic Fluid; Extracellular Matrix; Female; Fetal Death; Gestational Age; Humans; Hypoxia; Infant, Newborn; Placenta; Placental Circulation; Pre-Eclampsia; Pregnancy; Retrospective Studies; Tyrosine

2001
Phosphorylation of Bcl-2 and Bax proteins during hypoxia in newborn piglets.
    Neurochemical research, 2001, Volume: 26, Issue:1

    Topics: Adenosine Triphosphate; Animals; Animals, Newborn; bcl-2-Associated X Protein; Blotting, Western; Cerebral Cortex; Hypoxia; Neurons; Nuclear Envelope; Phosphocreatine; Phosphorylation; Precipitin Tests; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Swine; Tyrosine

2001
In vitro ischemia-reperfusion injury in term human placenta as a model for oxidative stress in pathological pregnancies.
    The American journal of pathology, 2001, Volume: 159, Issue:3

    Topics: Aldehydes; Cyclic N-Oxides; Deferoxamine; Female; Fluorescent Antibody Technique; Heat-Shock Proteins; HSP72 Heat-Shock Proteins; Humans; Hypoxia; Immunohistochemistry; Ischemia; Nitrogen Oxides; Oxidative Stress; Oxygen; Placenta; Pregnancy; Pregnancy Complications; Reactive Oxygen Species; Reperfusion Injury; Superoxide Dismutase; Tissue Distribution; Tyrosine

2001
Effects of oxygen and glucose deprivation on the expression and distribution of neuronal and inducible nitric oxide synthases and on protein nitration in rat cerebral cortex.
    The Journal of comparative neurology, 2002, Feb-04, Volume: 443, Issue:2

    Topics: Animals; Blotting, Western; Brain Ischemia; Calcium; Cerebral Cortex; Disease Models, Animal; Enzyme Inhibitors; Gene Expression; Glucose; Hypoxia; Immunohistochemistry; Magnetic Resonance Imaging; Male; Neurons; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Peroxynitrous Acid; Rats; Rats, Wistar; Reperfusion Injury; Tyrosine

2002
Microvascular endothelial cells differ in basal and hypoxia-regulated expression of angiogenic factors and their receptors.
    Microvascular research, 2002, Volume: 63, Issue:3

    Topics: Angiopoietin-1; Angiopoietin-2; Animals; Aryl Hydrocarbon Receptor Nuclear Translocator; Binding, Competitive; Blotting, Western; Cattle; Cells, Cultured; Cloning, Molecular; Corpus Luteum; DNA-Binding Proteins; DNA, Complementary; Endothelium, Vascular; Female; fms-Like Tyrosine Kinase 3; Humans; Hypoxia; Keratins; Membrane Glycoproteins; Neovascularization, Pathologic; Phenotype; Phosphorylation; Precipitin Tests; Protein Biosynthesis; Proto-Oncogene Proteins; Receptor Protein-Tyrosine Kinases; Receptor, TIE-2; Receptors, Aryl Hydrocarbon; Reverse Transcriptase Polymerase Chain Reaction; RNA; RNA, Messenger; Temperature; Transcription Factors; Tyrosine; Vascular Endothelial Growth Factor Receptor-1

2002
Brain tyrosine hydroxylation: alteration of oxygen affinity in vivo by immobilization or electroshock in the rat.
    Journal of neurochemistry, 1976, Volume: 27, Issue:1

    Topics: Animals; Behavior, Animal; Brain; Dopamine; Electroshock; Hypoxia; Immobilization; Male; Norepinephrine; Oxygen; Rats; Serotonin; Stress, Physiological; Tryptophan; Tryptophan Hydroxylase; Tyrosine; Tyrosine 3-Monooxygenase

1976
Effect of hypoxia on monoamine synthesis in brains of developing rats. II. Different length of exposure.
    Biology of the neonate, 1977, Volume: 32, Issue:3-4

    Topics: Animals; Brain; Dihydroxyphenylalanine; Hypoxia; Rats; Serotonin; Time Factors; Tryptophan; Tryptophan Hydroxylase; Tyrosine; Tyrosine 3-Monooxygenase

1977
Effect of hypoxia on monoamine synthesis in brains of developing rats. III. Various O2 levels.
    Biology of the neonate, 1978, Volume: 34, Issue:1-2

    Topics: 5-Hydroxytryptophan; Animals; Animals, Newborn; Brain; Dihydroxyphenylalanine; Female; Hypoxia; Norepinephrine; Oxygen Consumption; Pregnancy; Rats; Serotonin; Tryptophan; Tryptophan Hydroxylase; Tyrosine; Tyrosine 3-Monooxygenase

1978
Adaptation of brain monoamine synthesis to hypoxia in the rat.
    Journal of applied physiology, 1975, Volume: 39, Issue:2

    Topics: 5-Hydroxytryptophan; Animals; Biogenic Amines; Brain; Brain Chemistry; Chromatography, Ion Exchange; Dihydroxyphenylalanine; Dopa Decarboxylase; Dopamine; Hemoglobins; Hypoxia; Male; Norepinephrine; Rats; Serotonin; Tryptophan; Tyrosine; Tyrosine 3-Monooxygenase

1975
[Specific activity and release of norepinephrine in isolated and perfused rabbit hearts under various oxygen pressure].
    Bollettino della Societa italiana di biologia sperimentale, 1979, May-30, Volume: 55, Issue:10

    Topics: Animals; Glucose; Heart; Hypoxia; Mannitol; Myocardium; Norepinephrine; Oxygen; Partial Pressure; Perfusion; Rabbits; Tritium; Tyrosine

1979
Protein degradation in an isolated hypoxic heart muscle preparation: effect of glucose.
    Verhandlungen der Deutschen Gesellschaft fur Kreislaufforschung, 1977, Volume: 43

    Topics: Adenosine Triphosphate; Animals; Glucose; Hypoxia; Myocardium; Phosphocreatine; Rabbits; Tyrosine

1977
The metabolism of the bovine lens in air and nitrogen.
    Experimental eye research, 1975, Volume: 20, Issue:4

    Topics: Adenosine Triphosphate; Amino Acids; Animals; Buffers; Calcium; Carbon Radioisotopes; Cattle; Crystallins; Culture Media; Culture Techniques; HEPES; Hypoxia; Lactates; Lens, Crystalline; Nitrogen; Oxygen Consumption; Sodium; Tyrosine

1975
Enhancement of in vivo tyrosine hydroxylation in the rat adrenal gland under hypoxic conditions.
    Journal of neurochemistry, 1990, Volume: 54, Issue:4

    Topics: Adrenal Glands; Animals; Biopterins; Brain; Denervation; Dihydroxyphenylalanine; Hypoxia; Kinetics; Male; Oxidation-Reduction; Rats; Rats, Inbred Strains; Tyrosine; Tyrosine 3-Monooxygenase

1990
Monoamine neurotransmitter metabolism and locomotor activity during chemical hypoxia.
    Journal of neurochemistry, 1986, Volume: 46, Issue:3

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Corpus Striatum; Dopamine; Homovanillic Acid; Hydroxyindoleacetic Acid; Hypoxia; Male; Mice; Motor Activity; Nitrates; Serotonin; Tryptophan; Tyrosine

1986
The effects of cinepazide on the content, biosynthesis and turnover of noradrenaline, dopamine and 5-hydroxytryptamine in the rat brain under room air and hypoxia.
    Japanese journal of pharmacology, 1986, Volume: 41, Issue:1

    Topics: 5-Hydroxytryptophan; Animals; Brain; Dihydroxyphenylalanine; Dopamine; Hydroxyindoleacetic Acid; Hydroxylation; Hypoxia; Kinetics; Male; Norepinephrine; Piperazines; Rats; Serotonin; Tryptophan; Tyrosine; Vasodilator Agents

1986
Oxygen dependent regulation of mammalian ribonucleotide reductase in vivo and possible significance for replicon initiation.
    Biochemical and biophysical research communications, 1989, Aug-30, Volume: 163, Issue:1

    Topics: Binding Sites; Cytidine; Deoxycytosine Nucleotides; DNA Replication; Electron Spin Resonance Spectroscopy; Free Radicals; Hypoxia; In Vitro Techniques; Oxygen; Ribonucleotide Reductases; Tumor Cells, Cultured; Tyrosine

1989
Synthesis and release of catecholamines by the cat carotid body in vitro: effects of hypoxic stimulation.
    Brain research, 1986, May-21, Volume: 374, Issue:1

    Topics: Animals; Carotid Body; Carotid Sinus; Catecholamines; Cats; Dihydroxyphenylalanine; Dopamine; Electrophysiology; Hypoxia; In Vitro Techniques; Nerve Crush; Norepinephrine; Sympathectomy; Time Factors; Tyrosine

1986
Protein synthesis during hypoxia in fetal lambs.
    The American journal of physiology, 1987, Volume: 252, Issue:4 Pt 1

    Topics: Animals; Blood Glucose; Female; Fetal Blood; Hydrogen-Ion Concentration; Hypoxia; Lactates; Nitrogen; Pregnancy; Protein Biosynthesis; Sheep; Tyrosine

1987
Degree and duration of hypoxia needed to produce tyrosyluria.
    Lancet (London, England), 1972, Apr-01, Volume: 1, Issue:7753

    Topics: Aerospace Medicine; Chromatography, Gas; Humans; Hypoxia; Lactates; Phenols; Tyrosine

1972
Protection against m-fluorotyrosine convulsions and lethality in mice exposed to hypobaric hypoxia.
    The Journal of pharmacy and pharmacology, 1969, Volume: 21, Issue:7

    Topics: Animals; Atmospheric Pressure; Brain; Fluorine; Hypoxia; Male; Mice; Seizures; Tyrosine

1969
Alteration of rat brain catecholamine metabolism during exposure to hypobaric hypoxia.
    Canadian journal of physiology and pharmacology, 1972, Volume: 50, Issue:4

    Topics: Altitude; Animals; Brain; Brain Chemistry; Catecholamines; Chromatography, Ion Exchange; Dihydroxyphenylalanine; Dopamine; Ecological Systems, Closed; Hypoxia; Male; Methyltyrosines; Norepinephrine; Pressure; Rats; Time Factors; Tritium; Tyrosine

1972
The role of respiration in the energy metabolism of the bovine lens.
    The Biochemical journal, 1972, Volume: 129, Issue:2

    Topics: Adenosine Triphosphate; Aerobiosis; Animals; Carbon Isotopes; Cattle; Glucose; Hypoxia; In Vitro Techniques; Lactates; Lens, Crystalline; Nitrogen; Oxygen Consumption; Proteins; Sodium; Tyrosine

1972
Effect of hypoxia on tyrosine and tryptophan hydroxylation in unanaesthetized rat brain.
    Journal of neurochemistry, 1973, Volume: 20, Issue:3

    Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Brain; Brain Chemistry; Dihydroxyphenylalanine; Hydroxylation; Hypoxia; Male; Nitrogen; Oxygen; Rats; Serotonin; Tryptophan; Tyrosine

1973
[Protein synthesis dynamics in the neurons and glia of the rat brain during their adaptation to high hypoxia].
    Tsitologiia, 1973, Volume: 15, Issue:3

    Topics: Adaptation, Physiological; Altitude; Animals; Atmospheric Pressure; Autoradiography; Brain Chemistry; Cerebral Cortex; Environment, Controlled; Hypothalamus; Hypoxia; Male; Neuroglia; Neurons; Protein Biosynthesis; Pyramidal Tracts; Rats; Time Factors; Tritium; Tyrosine

1973
[Dynamics of protein synthesis in the contractile myocardium and smooth muscles of the intramural branches of the coronary arteries in adaptation to continuous and interrupted hypoxia].
    Kardiologiia, 1973, Volume: 13, Issue:4

    Topics: Adaptation, Physiological; Altitude; Animals; Autoradiography; Cell Nucleus; Coronary Vessels; Cytoplasm; Hypoxia; Injections, Intraperitoneal; Male; Muscle Proteins; Muscle, Smooth; Myocardium; Rats; Tritium; Tyrosine

1973
[Protein synthesis in rat stellate ganglion neurons and glial cells during adaptation to high altitude].
    Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova, 1973, Volume: 59, Issue:3

    Topics: Adaptation, Physiological; Altitude; Animals; Hypoxia; Nerve Tissue Proteins; Neuroglia; Neurons; Rats; Stellate Ganglion; Tritium; Tyrosine

1973
[Dynamics of protein synthesis in cerebral neurons and glia during adaptation to high-altitude hypoxia].
    Doklady Akademii nauk SSSR, 1972, May-21, Volume: 204, Issue:3

    Topics: Acclimatization; Altitude; Animals; Autoradiography; Cerebral Cortex; Hypoxia; Male; Nerve Tissue Proteins; Neuroglia; Neurons; Rats; Rats, Inbred Strains; Tritium; Tyrosine

1972
[Change in the proteolytic activity of the thyroid gland following administration of glutamic acid in normal conditions and in hypoxia].
    Nauchnye doklady vysshei shkoly. Biologicheskie nauki, 1971, Volume: 4, Issue:88

    Topics: Animals; Glutamates; Hypoxia; Male; Peptide Hydrolases; Rats; Thyroid Gland; Tyrosine

1971
Effect of hypoxic hypoxia on the catecholamine content and some cytochemical changes in the hypothalamus of the cat.
    Aerospace medicine, 1969, Volume: 40, Issue:5

    Topics: Aerospace Medicine; Altitude; Animals; Atmospheric Pressure; Catecholamines; Cats; Dihydroxyphenylalanine; Female; Histocytochemistry; Hypothalamus; Hypoxia; Male; Neurosecretion; Tyrosine

1969
Ultrastructure of S-91 mouse melanomas subjected to phenylalanine and tyrosine restriction in vivo.
    The American journal of pathology, 1966, Volume: 49, Issue:2

    Topics: Animals; Endoplasmic Reticulum; Hypoxia; Melanoma; Mice; Microscopy, Electron; Mitochondria; Neoplasms, Experimental; Tyrosine

1966
Thyroxine biosynthesis and thyroidal uptake of I131 in rats at the onset of hypoxia exposure.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1966, Volume: 121, Issue:4

    Topics: Altitude; Animals; Diiodotyrosine; Hypoxia; In Vitro Techniques; Iodine Isotopes; Rats; Subcellular Fractions; Thyroid Gland; Thyroxine; Tyrosine

1966