tyrosine has been researched along with Experimental Hepatoma in 49 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 20 (40.82) | 18.7374 |
| 1990's | 19 (38.78) | 18.2507 |
| 2000's | 5 (10.20) | 29.6817 |
| 2010's | 5 (10.20) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dombrowski, F; Görlach, A; Jakupovic, M; Kietzmann, T; Konzack, A; Kubaichuk, K; Miinalainen, I; Sormunen, R | 1 |
| Kupriyanova, ES; Naumov, AA; Potselueva, MM | 1 |
| Chen, H; Li, Y; Yu, YN | 1 |
| Barnes, KF; Bhatia, D; Bishayee, A; Carroll, RT; Darvesh, AS | 1 |
| Bhatia, D; Bishayee, A; Darvesh, AS; Meszaros, JG; Ohanyan, V; Thoppil, RJ | 1 |
| Barnes, KF; Bhatia, D; Bishayee, A; Darvesh, AS; Haznagy-Radnai, E; Hohmann, J; Thoppil, RJ | 1 |
| Granner, DK; Hall, RK; Law, BK; Nawano, M; Waltner-Law, ME; Wang, XL | 1 |
| Imamura, F; Inoue, M; Iwasaki, T; Kobayashi, S; Mukai, M; Murakami-Murofushi, K; Nakamura, H; Tatsuta, M; Togawa, A | 1 |
| Argilés, JM; Barreiro, E; Busquets, S; de la Puente, B; Gea, J; López-Soriano, FJ | 1 |
| Niwa, A; Sorimachi, K; Yamamoto, K; Yasumura, Y | 1 |
| Blith, DL; Häring, HU; Kahn, CR; Karlsson, FA; Kasuga, M; Zick, Y | 1 |
| Goto, T; Nishimura, S; Ohgi, T; Okada, N; Shindo-Okada, N | 1 |
| Kim, G; Yurkow, EJ | 1 |
| Lazar, DF; Milarski, KL; Saltiel, AR; Wiese, RJ | 1 |
| Ahmad, F; Goldstein, BJ; Li, PM; Meyerovitch, J | 1 |
| Mizuno, K; Nakamura, T; Nozawa, Y; Okano, Y; Osada, S | 1 |
| Schwartz, CF | 1 |
| Hosomi, Y; Ogawa, W; Roth, RA | 1 |
| Feinstein, R; Kanety, H; Karasik, A; Lunenfeld, B; Papa, MZ | 1 |
| Akedo, H; Imamura, F; Isoai, A; Kitagawa, I; Kobayashi, M; Mukai, M; Shinkai, K | 1 |
| Goldstein, BJ; Li, PM | 1 |
| Auguste, P; Froger, J; Gascan, H; Olivier, C; Pouplard-Barthelaix, A; Praloran, V; Robledo, O | 1 |
| Garbe, C; Lassmann, G; Pötsch, S; Wellnitz, U | 1 |
| Furusaka, A; Hiramoto, J; Hiyane, S; Nagayama, K; Nakada, T; Ogasawara, H; Shirahama, K; Takahashi, M; Tanaka, T | 1 |
| Lukes, H; McDiarmid, H; Werner, J; Yau, L; Zahradka, P | 1 |
| Fernandis, AZ; Krishnamurthy, SC; Prabhudesai, S; Rao, KV; Subrahmanyam, G; Sundarrajan, M | 1 |
| Kokolis, N; Stichler, W; Ziegler, I | 1 |
| Goldfine, ID; Sung, CK | 1 |
| Bassel-Duby, R; Bittick, T; Gething, MJ; Jiang, NY; Madison, E; McGookey, D; Orth, K; Sambrook, J; Shohet, R | 1 |
| Araki, E; Backer, JM; Miralpeix, M; Myers, MG; Sun, XJ; White, MF | 1 |
| Backer, JM; White, MF | 1 |
| Behnke, B; Gebhardt, A; Kahn, CR; Krone, W; Müller-Wieland, D; Neumann, S; White, MF | 1 |
| Hidaka, Y; Ishida, F; Kamei, T; Nagata, Y | 1 |
| Dull, TJ; Kahn, CR; Stegmann, EW; Ullrich, A; White, MF | 1 |
| Backer, JM; Kahn, CR; White, MF | 2 |
| Akanuma, Y; Hirata, Y; Kasuga, M; Koshio, O; Momomura, K; Takaku, F; Takayama-Hasumi, S; Tashiro-Hashimoto, Y; Tobe, K | 1 |
| Akanuma, Y; Izumi, T; Kasuga, M; Koshio, O; Takaku, F; Tashiro-Hashimoto, Y; Tobe, K | 1 |
| Del Carlo, C; Fanciulli, M; Floridi, A; Mancini, A; Paggi, MG; Perrotti, N; Taylor, SI | 1 |
| Ballotti, R; Kowalski, A; Scimeca, JC; Van Obberghen, E | 1 |
| Kahn, CR; Pang, DT; Shafer, JA; Sharma, BR; White, MF | 1 |
| Gibbs, EM; Gould, GW; Lienhard, GE; Watts, TD; Witters, LA | 1 |
| Kahn, CR; Takayama, S; White, MF | 1 |
| Avruch, J; Frackelton, AR; Gunsalus, JR; Nemenoff, RA; Pierce, MW; Tornqvist, HE | 1 |
| Paxton, K; Ward, LC; Wilce, PA | 1 |
| Abdallah, RM; Meadows, GG; Starkey, JR | 1 |
| Laberge, C; Lescault, A; Tanguay, RM | 1 |
| Imazu, M; Takeda, M; Tsukamoto, H; Usui, H; Yoshikawa, K | 1 |
| Czech, MP; Yu, KT | 1 |
49 other study(ies) available for tyrosine and Experimental Hepatoma
| Article | Year |
|---|---|
Mitochondrial Dysfunction Due to Lack of Manganese Superoxide Dismutase Promotes Hepatocarcinogenesis.
Topics: Animals; Carcinoma, Hepatocellular; Cell Hypoxia; Cell Proliferation; Cell Shape; Cell Transformation, Neoplastic; Diethylnitrosamine; Hep G2 Cells; Hepatocytes; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Liver Neoplasms, Experimental; Male; Mice, Knockout; Mitochondria; Reactive Oxygen Species; Superoxide Dismutase; Tyrosine; Wnt Signaling Pathway | 2015 |
[DYNAMICS OF NITROGEN OXIDE METABOLITES IN THE PLASMA AND ASCITES DURING ZAJDEL HEPATOMA GROWTH IN VIVO].
Topics: Animals; Ascitic Fluid; Liver Neoplasms, Experimental; Nitrogen Oxides; Rats; Tyrosine | 2015 |
Effect of bicyclol on cisplatin-induced hepatotoxicity in the hepatocarcinoma 22 tumour-bearing mice.
Topics: Animals; Antineoplastic Agents; Biphenyl Compounds; Blotting, Western; Carcinoma, Hepatocellular; Cell Line, Tumor; Chemical and Drug Induced Liver Injury; Cisplatin; Drug Interactions; Gene Expression Regulation; L-Lactate Dehydrogenase; Liver; Liver Diseases; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred ICR; Nitric Oxide Synthase Type II; Transaminases; Tyrosine | 2009 |
Resveratrol suppresses oxidative stress and inflammatory response in diethylnitrosamine-initiated rat hepatocarcinogenesis.
Topics: Animals; Antioxidants; Carcinogens; Chemical and Drug Induced Liver Injury; Diethylnitrosamine; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Enzyme Induction; Female; Hyperplasia; Inflammation; Lipid Peroxidation; Liver; Liver Neoplasms, Experimental; NF-E2-Related Factor 2; Nitric Oxide Synthase Type II; Oxidative Stress; Phenobarbital; Precancerous Conditions; Rats; Rats, Sprague-Dawley; Resveratrol; RNA, Messenger; Stilbenes; Tyrosine | 2010 |
Pomegranate phytoconstituents blunt the inflammatory cascade in a chemically induced rodent model of hepatocellular carcinogenesis.
Topics: Animals; Anticarcinogenic Agents; Carcinoma, Hepatocellular; Cyclooxygenase 2; Diethylnitrosamine; Echocardiography; Heart; HSP70 Heat-Shock Proteins; HSP90 Heat-Shock Proteins; Inflammation; Liver; Liver Neoplasms; Liver Neoplasms, Experimental; Lythraceae; Male; NF-kappa B; Nitric Oxide Synthase Type II; Plant Extracts; Rats; Rats, Sprague-Dawley; Tyrosine | 2013 |
Black currant anthocyanins abrogate oxidative stress through Nrf2- mediated antioxidant mechanisms in a rat model of hepatocellular carcinoma.
Topics: Alkylating Agents; Animals; Anthocyanins; Antioxidants; Blotting, Western; Carcinoma, Hepatocellular; Diet; Diethylnitrosamine; Glutathione Transferase; Immunoenzyme Techniques; Lipid Peroxidation; Liver Neoplasms, Experimental; Male; NF-E2-Related Factor 2; Nitric Oxide Synthase Type II; Oxidative Stress; Phytotherapy; Rats; Rats, Sprague-Dawley; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; Ribes; RNA, Messenger; Signal Transduction; Tyrosine | 2012 |
Epigallocatechin gallate, a constituent of green tea, represses hepatic glucose production.
Topics: Acetylcysteine; Animals; Catechin; Gene Expression Regulation, Enzymologic; Gluconeogenesis; Glucose; Glucose-6-Phosphatase; Insulin; Liver; Liver Neoplasms, Experimental; Phosphorylation; Protein Serine-Threonine Kinases; Rats; Signal Transduction; Superoxide Dismutase; Tumor Cells, Cultured; Tyrosine | 2002 |
Cyclic phosphatidic acid inhibits RhoA-mediated autophosphorylation of FAK at Tyr-397 and subsequent tumor-cell invasion.
Topics: Animals; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Liver Neoplasms; Liver Neoplasms, Experimental; Neoplasm Invasiveness; Phosphatidic Acids; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Rats; Rats, Inbred Strains; rhoA GTP-Binding Protein; Tyrosine | 2003 |
Both oxidative and nitrosative stress are associated with muscle wasting in tumour-bearing rats.
Topics: Animals; Antioxidants; Biomarkers; Cachexia; Catalase; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Liver Neoplasms, Experimental; Male; Muscle, Skeletal; Muscular Atrophy; Oxidative Stress; Rats; Reactive Nitrogen Species; Reactive Oxygen Species; Superoxide Dismutase; Tyrosine | 2005 |
Continuous culture of Reuber hepatoma cells in serum-free arginine-, glutamine- and tyrosine-deprived chemically defined medium.
Topics: Animals; Arginase; Arginine; Argininosuccinate Lyase; Argininosuccinate Synthase; Carbamoyl-Phosphate Synthase (Ammonia); Culture Media; Glutamine; Liver Neoplasms, Experimental; Ornithine Carbamoyltransferase; Phenylalanine Hydroxylase; Rats; Tyrosine; Tyrosine Transaminase | 1980 |
Insulin stimulation of phosphorylation of the beta subunit of the insulin receptor. Formation of both phosphoserine and phosphotyrosine.
Topics: Amino Acids; Animals; Insulin; Liver Neoplasms, Experimental; Macromolecular Substances; Molecular Weight; Phosphorylation; Phosphoserine; Phosphotyrosine; Rats; Receptor, Insulin; Serine; Tyrosine | 1982 |
Transfer ribonucleic acid guanine transglycosylase isolated from rat liver.
Topics: Animals; Escherichia coli; Guanine; Kinetics; Liver; Liver Neoplasms, Experimental; Nucleoside Q; Pentosyltransferases; Rats; RNA, Transfer; Transferases; Tyrosine | 1980 |
Effects of chromium on basal and insulin-induced tyrosine phosphorylation in H4 hepatoma cells: comparison with phorbol-12-myristate-13-acetate and sodium orthovanadate.
Topics: Animals; Chromium; Insulin; Insulin Receptor Substrate Proteins; Liver Neoplasms, Experimental; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Phosphotyrosine; Protein Kinase C; Proteins; Rats; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tyrosine; Vanadates | 1995 |
Detection of a 60 kDa tyrosine-phosphorylated protein in insulin-stimulated hepatoma cells that associates with the SH2 domain of phosphatidylinositol 3-kinase.
Topics: Amino Acid Sequence; Animals; Cells, Cultured; Insulin; Liver; Liver Neoplasms, Experimental; Molecular Sequence Data; Molecular Weight; Peptides; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphotransferases (Alcohol Group Acceptor); Phosphotyrosine; Protein Binding; Rats; Receptor, Insulin; Signal Transduction; Tyrosine | 1995 |
Osmotic loading of neutralizing antibodies demonstrates a role for protein-tyrosine phosphatase 1B in negative regulation of the insulin action pathway.
Topics: Animals; Antibodies; Antibody Specificity; Cell Line; Immunoblotting; Immunoglobulin G; Insulin; Kinetics; Liver Neoplasms, Experimental; Phosphotyrosine; Protein Tyrosine Phosphatases; Rabbits; Rats; Receptor, Insulin; Tyrosine | 1995 |
Tyrosine phosphorylation of phospholipase C gamma in c-met/HGF receptor-stimulated hepatocytes: comparison with HepG2 hepatocarcinoma cells.
Topics: Animals; Cells, Cultured; Hepatocyte Growth Factor; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Liver; Liver Neoplasms, Experimental; Phosphorylation; Phosphotyrosine; Proto-Oncogene Proteins c-met; Rats; Receptors, Cell Surface; Tumor Cells, Cultured; Type C Phospholipases; Tyrosine | 1993 |
Insulin regulation of protein phosphorylation in H4 hepatoma cells. Examination of rapid effects using two-dimensional electrophoresis.
Topics: Animals; Arsenicals; Electrophoresis, Gel, Two-Dimensional; Insulin; Kinetics; Liver Neoplasms, Experimental; Molecular Weight; Neoplasm Proteins; Phosphoproteins; Phosphotyrosine; Protease Inhibitors; Rats; Tumor Cells, Cultured; Tyrosine | 1993 |
Activation of protein kinase C stimulates the tyrosine phosphorylation and guanosine triphosphatase-activating protein association of p60 in rat hepatoma cells.
Topics: Animals; Down-Regulation; GTPase-Activating Proteins; Insulin; Liver Neoplasms, Experimental; Phosphorylation; Protein Kinase C; Proteins; Rats; Receptor, Insulin; Second Messenger Systems; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tyrosine | 1995 |
Tumor necrosis factor-alpha suppresses insulin-induced tyrosine phosphorylation of insulin receptor and its substrates.
Topics: Animals; Cell Survival; Insulin; Liver Neoplasms, Experimental; Phosphorylation; Rats; Receptor, Insulin; Signal Transduction; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Tyrosine | 1993 |
Inhibition of in vitro tumor cell invasion by ginsenoside Rg3.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Carbohydrate Sequence; Carcinoma, Small Cell; Ginsenosides; Humans; Liver Neoplasms, Experimental; Lung Neoplasms; Lysophospholipids; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Proteins; Pancreatic Neoplasms; Phosphorylation; Rats; Rats, Inbred Strains; Saponins; Tyrosine | 1996 |
Differential regulation of insulin-stimulated tyrosine phosphorylation of IRS-1 and SHC by Wortmannin in intact cells.
Topics: Androstadienes; Animals; Cell Line; Enzyme Inhibitors; Insulin; Insulin Receptor Substrate Proteins; Kinetics; Liver Neoplasms, Experimental; Phosphates; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotransferases (Alcohol Group Acceptor); Phosphotyrosine; Rats; Receptor, Insulin; Tumor Cells, Cultured; Tyrosine; Wortmannin | 1996 |
Alanine substitution for Thr268 and Asp269 of soluble ciliary neurotrophic factor (CNTF) receptor alpha component defines a specific antagonist for the CNTF response.
Topics: Alanine; Amino Acid Sequence; Animals; Aspartic Acid; Binding, Competitive; Cell Division; Cell Line; Ciliary Neurotrophic Factor; Haptoglobins; Liver Neoplasms, Experimental; Molecular Sequence Data; Mutagenesis, Site-Directed; Nerve Tissue Proteins; Phosphorylation; Rats; Receptor, Ciliary Neurotrophic Factor; Receptors, Nerve Growth Factor; Sequence Alignment; Solubility; Threonine; Tyrosine | 1996 |
Inactivation of ribonucleotide reductase in tumour cells and inhibition of tumour cell growth by p-alkoxyphenols.
Topics: Animals; Cell Division; Electron Spin Resonance Spectroscopy; Enzyme Activation; HL-60 Cells; Humans; Liver Neoplasms, Experimental; Melanoma; Phenols; Rats; Ribonucleotide Reductases; Tumor Cells, Cultured; Tyrosine | 1997 |
Hepatocyte growth factor stimulates DNA synthesis in rat preneoplastic hepatocytes but not in liver carcinoma cells.
Topics: Animals; Bromodeoxyuridine; DNA; Hepatocyte Growth Factor; Humans; Immunohistochemistry; Liver Neoplasms, Experimental; Male; Methyldimethylaminoazobenzene; Phosphorylation; Precancerous Conditions; Proto-Oncogene Proteins c-met; Rats; Type C Phospholipases; Tyrosine | 1998 |
Insulin-like growth factor-I (IGF-I)-dependent activation of pp42/44 mitogen-activated protein kinase occurs independently of IGF-I receptor kinase activation and IRS-1 tyrosine phosphorylation.
Topics: Animals; Biological Transport, Active; Cell Division; Enzyme Activation; Glucose; Insulin; Insulin Receptor Substrate Proteins; Insulin-Like Growth Factor I; Liver Neoplasms, Experimental; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Phosphoproteins; Phosphorylation; Rats; Receptor, IGF Type 1; Receptor, Insulin; Signal Transduction; Tumor Cells, Cultured; Tyrosine | 1999 |
Overexpression of G1/S cyclins and PCNA and their relationship to tyrosine phosphorylation and dephosphorylation during tumor promotion by metanil yellow and malachite green.
Topics: Animals; Azo Compounds; Cyclins; Diethylnitrosamine; Food Coloring Agents; G1 Phase; Liver Neoplasms, Experimental; Male; Phosphorylation; Precancerous Conditions; Proliferating Cell Nuclear Antigen; Rats; Rosaniline Dyes; S Phase; Tyrosine | 2000 |
In vivo metabolism of deutero-L-phenylalanine and deutero-L-tyrosine in normal and in various tumor-bearing rats.
Topics: Animals; Biopterins; Deuterium; Female; Hydroxylation; Kinetics; Liver Neoplasms, Experimental; Male; Phenylalanine; Phenylalanine Hydroxylase; Rats; Sarcoma, Experimental; Tyrosine | 1977 |
Phosphatidylinositol-3-kinase is a non-tyrosine phosphorylated member of the insulin receptor signalling complex.
Topics: Animals; Antibodies; Humans; Insulin; Kinetics; Liver Neoplasms, Experimental; Phosphatidylinositol 3-Kinases; Phosphorylation; Phosphotransferases; Phosphotyrosine; Rats; Receptor, Insulin; Signal Transduction; Transfection; Tumor Cells, Cultured; Tyrosine | 1992 |
Tyrosine 67 in the epidermal growth factor-like domain of tissue-type plasminogen activator is important for clearance by a specific hepatic receptor.
Topics: Amino Acid Sequence; Animals; Base Sequence; Binding Sites; Cell Line; Electrophoresis, Polyacrylamide Gel; Endocytosis; Epidermal Growth Factor; Hemolysis; Humans; Kinetics; Liver Neoplasms, Experimental; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Oligodeoxyribonucleotides; Protein Conformation; Rats; Receptors, Cell Surface; Receptors, Urokinase Plasminogen Activator; Recombinant Proteins; Substrate Specificity; Tissue Plasminogen Activator; Transfection; Tyrosine | 1992 |
Insulin stimulates tyrosine phosphorylation of multiple high molecular weight substrates in Fao hepatoma cells.
Topics: Amino Acid Sequence; Animals; Blotting, Western; In Vitro Techniques; Insulin; Liver Neoplasms, Experimental; Molecular Sequence Data; Molecular Weight; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Phosphotransferases; Phosphotyrosine; Protein-Tyrosine Kinases; Receptor, Insulin; Time Factors; Tumor Cells, Cultured; Tyrosine | 1992 |
Preparation and use of anti-phosphotyrosine antibodies to study structure and function of insulin receptor.
Topics: Animals; Antibodies; Cell Line; CHO Cells; Chromatography, Affinity; Cricetinae; Electrophoresis, Polyacrylamide Gel; Humans; Immunoblotting; Indicators and Reagents; Insulin; Liver Neoplasms, Experimental; Macromolecular Substances; Molecular Weight; Neoplasm Proteins; Phosphates; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorus Radioisotopes; Phosphotransferases; Phosphotyrosine; Protein-Tyrosine Kinases; Rabbits; Receptor, Insulin; Transfection; Tyrosine | 1991 |
Pertussis toxin inhibits autophosphorylation and activation of the insulin receptor kinase.
Topics: Animals; Cell Line; Enzyme Activation; Insulin; Kinetics; Liver Neoplasms, Experimental; Molecular Weight; Pertussis Toxin; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Rats; Receptor, Insulin; Tyrosine; Virulence Factors, Bordetella | 1991 |
Effects of simvastatin (MK-733) on branched pathway of mevalonate.
Topics: Animals; Anticholesteremic Agents; Cell Line; Cholesterol; DNA; Dolichols; Humans; Liver Neoplasms, Experimental; Lovastatin; Mevalonic Acid; Proteins; Simvastatin; Thymidine; Tumor Cells, Cultured; Tyrosine; Ubiquinone | 1990 |
Characterization of an endogenous substrate of the insulin receptor in cultured cells.
Topics: Animals; Cell Line; Cloning, Molecular; Humans; Insulin; Liver Neoplasms, Experimental; Phosphorus Radioisotopes; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Receptor, Insulin; Tetradecanoylphorbol Acetate; Tyrosine | 1987 |
Tyrosine phosphorylation of the insulin receptor during insulin-stimulated internalization in rat hepatoma cells.
Topics: Algorithms; Animals; Cell Line; Insulin; Liver Neoplasms, Experimental; Models, Biological; Phosphorylation; Phosphotyrosine; Rats; Receptor, Insulin; Tyrosine | 1989 |
Autoantibodies to the insulin receptor (B-10) can stimulate tyrosine phosphorylation of the beta-subunit of the insulin receptor and a 185,000 molecular weight protein in rat hepatoma cells.
Topics: Adipose Tissue; Animals; Autoantibodies; Cells, Cultured; Electrophoresis, Polyacrylamide Gel; Immunoglobulin G; Insulin; Liver Neoplasms, Experimental; Molecular Weight; Neoplasm Proteins; Peptide Hydrolases; Peptide Mapping; Phosphoproteins; Phosphorylation; Phosphotyrosine; Precipitin Tests; Protein-Tyrosine Kinases; Rats; Receptor, Insulin; Tyrosine | 1989 |
Tyrosine phosphorylation of pp185 by insulin receptor kinase in a cell-free system.
Topics: Animals; Antigen-Antibody Reactions; Cell-Free System; Electrophoresis, Gel, Two-Dimensional; Insulin; Liver Neoplasms, Experimental; Molecular Weight; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Receptor, Insulin; Time Factors; Tumor Cells, Cultured; Tyrosine | 1989 |
rp-120: a common endogenous substrate for insulin and IGF-1 receptor-associated tyrosine kinase activity in the highly malignant AS-30D rat hepatoma cells.
Topics: Animals; Female; Immunosorbent Techniques; Insulin; Insulin-Like Growth Factor I; Liver Neoplasms, Experimental; Membrane Glycoproteins; Microsomes, Liver; Molecular Weight; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Rats; Rats, Inbred Strains; Receptor, Insulin; Receptors, Cell Surface; Receptors, Somatomedin; Tumor Cells, Cultured; Tyrosine | 1989 |
Tyrosine phosphorylation of the insulin receptor is not required for receptor internalization: studies in 2,4-dinitrophenol-treated cells.
Topics: 2,4-Dinitrophenol; Adenosine Triphosphate; Animals; Biological Transport; Dinitrophenols; Immunosorbent Techniques; Insulin; Iodine Radioisotopes; Liver Neoplasms, Experimental; Phosphorylation; Phosphotyrosine; Receptor, Insulin; Tumor Cells, Cultured; Tyrosine; Uncoupling Agents | 1989 |
Antiphosphotyrosine antibodies modulate insulin receptor kinase activity and insulin action.
Topics: Amino Acids; Animals; Antibodies; Antibody Specificity; Biological Transport; Cell-Free System; Glucose; Insulin; Liver Neoplasms, Experimental; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Rats; Receptor, Insulin; Tumor Cells, Cultured; Tyrosine | 1989 |
Predominance of tyrosine phosphorylation of insulin receptors during the initial response of intact cells to insulin.
Topics: Animals; Antibodies; Cell Line; Dose-Response Relationship, Drug; Immunosorbent Techniques; Insulin; Liver Neoplasms, Experimental; Phosphorylation; Phosphotyrosine; Receptor, Insulin; Tyrosine | 1985 |
Regulation of protein phosphorylation by insulin and an insulinomimetic oligosaccharide in 3T3-L1 adipocytes and Fao hepatoma cells.
Topics: Adipose Tissue; Animals; Cell Line; Insulin; Liver Neoplasms, Experimental; Molecular Weight; Oligosaccharides; Phosphorylation; Protein-Tyrosine Kinases; Proteins; Rats; Receptor, Insulin; Tyrosine | 1988 |
Phorbol ester-induced serine phosphorylation of the insulin receptor decreases its tyrosine kinase activity.
Topics: Adenosine Triphosphate; Alkaline Phosphatase; Animals; Chromatography, Affinity; Insulin; Liver Neoplasms, Experimental; Phosphorylation; Phosphoserine; Phosphothreonine; Protein-Tyrosine Kinases; Rats; Receptor, Insulin; Serine; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tyrosine | 1988 |
Identification of the insulin receptor tyrosine residues undergoing insulin-stimulated phosphorylation in intact rat hepatoma cells.
Topics: Amino Acid Sequence; Animals; Insulin; Liver Neoplasms, Experimental; Molecular Weight; Peptide Fragments; Phosphorylation; Rats; Receptor, Insulin; Tyrosine | 1988 |
Amino acid oxidation in the tumor-bearing rat.
Topics: Animals; Body Weight; Leucine; Liver Neoplasms, Experimental; Male; Organ Size; Oxidation-Reduction; Rats; Rats, Inbred BUF; Tyrosine | 1988 |
Dietary restriction of tyrosine and phenylalanine: inhibition of metastasis of three rodent tumors.
Topics: Animals; Diet; Liver Neoplasms, Experimental; Lung Neoplasms; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Neoplasm Metastasis; Neoplasm Transplantation; Neoplasms, Experimental; Phenylalanine; Tyrosine | 1987 |
Hereditary tyrosinemias (type I): a new vista on tyrosine toxicity and cancer.
Topics: Amino Acid Metabolism, Inborn Errors; Animals; Humans; Liver; Liver Neoplasms, Experimental; Neoplasms; Tyrosine | 1986 |
Comparison of tyrosine phosphorylation of proteins by membrane fractions from mouse liver, Ehrlich ascites tumor and MH134 hepatoma.
Topics: Animals; Carcinoma, Ehrlich Tumor; Electrophoresis, Polyacrylamide Gel; Epidermal Growth Factor; In Vitro Techniques; Liver; Liver Neoplasms, Experimental; Male; Membrane Proteins; Mice; Mice, Inbred C3H; Phosphorylation; Protein Kinases; Protein-Tyrosine Kinases; Tyrosine | 1985 |
Tyrosine phosphorylation of insulin receptor beta subunit activates the receptor tyrosine kinase in intact H-35 hepatoma cells.
Topics: Amino Acids; Animals; Cell Line; Chromatography, High Pressure Liquid; Enzyme Activation; Kinetics; Liver Neoplasms, Experimental; Macromolecular Substances; Peptide Fragments; Phosphorus Radioisotopes; Phosphorylation; Protein-Tyrosine Kinases; Rats; Receptor, Insulin; Trypsin; Tyrosine | 1986 |