tyrosine and Diabetic Retinopathy

tyrosine has been researched along with Diabetic Retinopathy in 38 studies

Research

Studies (38)

TimeframeStudies, this research(%)All Research%
pre-19901 (2.63)18.7374
1990's0 (0.00)18.2507
2000's18 (47.37)29.6817
2010's15 (39.47)24.3611
2020's4 (10.53)2.80

Authors

AuthorsStudies
Chen, K; Gao, X; Hu, C; Jiang, Z; Liu, K1
Cho, CH; Kim, HW; Lim, NY; Park, S; Park, SJ; Roh, KH1
Carragher, NO; Feyen, JHM; Hu, TT; Moons, L; Porcu, M; Sergeys, J; Temps, C; Unciti-Broceta, A; Van Hove, I1
Fang, ZZ; Feng, XF; Li, J; Luo, HH; Sun, XY; Yang, X1
Kowluru, RA; Mishra, M1
Chen, Q; Ma, JX; Murray, AR; Park, K; Takahashi, Y; Zhou, KK1
Bhattacharya, B; Chatterjee, M; Choudhuri, S; Chowdhury, IH; Dutta, D; Kundu, S; Mandal, LK; Mitra, B; Sen, A1
Caldwell, RB; Caldwell, RW; Chandler, P; Lemtalsi, T; Rojas, M; Toque, HA; Xu, Z; Zhang, W1
Catharino, RR; de Oliveira, MG; de Souza, GF; Duarte, DA; Ferreira, MS; Lopes de Faria, JB; Lopes de Faria, JM; Rosales, MA; Silva, KC1
Bakariş, S; Durdu, H; Ergün, Y; Ganiyusufoğlu, E; Kılınç, M; Ozdemir, G1
Gong, Y; He, S; Hou, B; Li, Z1
Ergün, Y; Kılınç, M; Ozdemir, G; Sahin, E1
Chan, PS; Kanwar, M; Kowluru, RA; Zhang, JP1
Feng, W; Ge, Y; Hong, J; Shuai, J; Yuan, Z; Zheng, Q1
Abengoechea, S; Ballester, J; Elizalde, J; Fernández-Novell, JM; Guinovart, JJ; Nadal, J; Ramió-Lluch, L; Reverter, JL; Rivera, MM; Rodríguez-Gil, JE1
Bucolo, C; Cuzzocrea, S; Drago, F; Mazzon, E; Ward, KW1
Cai, L; Guo, W; Ji, S; Li, C; Li, X; Tan, Y; Zhang, C1
Alvarez-Nölting, R; Araiz, J; Arnal, E; Bosch-Morell, F; Cervera, E; Díaz-Llopis, M; Johnsen-Soriano, S; Miranda, M; Romero, FJ1
Arnal, E; Bosch-Morell, F; Cervera, E; Javier Romero, F; Johnsen-Soriano, S; Miranda, M; Navea, A; Sancho-Tello, M1
Lopes de Faria, JB; Lopes de Faria, JM; Rosales, MA; Silva, KC1
de Faria, JB; de Faria, JM; Rosales, MA; Silva, KC1
Das, A; Maestas, J; McGuire, PG; Rangasamy, S; Srinivasan, R1
Abengoechea, S; Ballester, J; Elizalde, J; Fernández-Novell, JM; Nadal, J; Ramió-Lluch, L; Reverter, JL; Rivera, MM; Rodriguez, JE1
He, C; Li, H; Lin, M; Lyons, TJ; Xie, Z; Zou, MH1
Alhusban, A; El-Remessy, AB; Elmarkaby, AA; Matragoon, S; Mohamed, IN; Pillai, BA; Soliman, SA1
Kowluru, RA1
Chakrabarti, S; Chen, S; Koppolu, P; Kowluru, RA1
Mabley, JG; Obrosova, IG; Pacher, P; Szabó, C1
Ge, YB; Liu, QH; Xie, P; Yuan, XR1
Atasi, L; Ho, YS; Kowluru, RA1
Giorgetti-Peraldi, S; Hasseine, LK; Longnus, S; Murdaca, J; Suavet, F; Van Obberghen, E1
Biswas, SK; De Faria, JB; De Faria, JM; Martins, N; Pinto, CC; Silva, KC1
Crabb, JS; Crabb, JW; Du, Y; Gu, X; Kern, TS; Zhan, X1
Gierhart, DL; Kowluru, RA; Menon, B1
Ali, TK; Drel, VR; El-Remessy, AB; Julius, U; Obrosova, IG; Pacher, P; Shin, J1
Du, Y; Kern, TS; Miller, CM; Smith, MA1
Courtois, Y; Goureau, O; Sennlaub, F1
Kuriyama, K; Nishimura, C1

Reviews

1 review(s) available for tyrosine and Diabetic Retinopathy

ArticleYear
Role of nitrosative stress and peroxynitrite in the pathogenesis of diabetic complications. Emerging new therapeutical strategies.
    Current medicinal chemistry, 2005, Volume: 12, Issue:3

    Topics: Animals; Cardiomyopathies; Diabetes Complications; Diabetic Angiopathies; Diabetic Nephropathies; Diabetic Neuropathies; Diabetic Retinopathy; Endothelium, Vascular; Humans; Nitric Oxide; Oxidative Stress; Peroxynitrous Acid; Poly(ADP-ribose) Polymerases; Superoxides; Tyrosine

2005

Other Studies

37 other study(ies) available for tyrosine and Diabetic Retinopathy

ArticleYear
Captopril alleviates oxidative damage in diabetic retinopathy.
    Life sciences, 2022, Feb-01, Volume: 290

    Topics: Animals; Captopril; Cholesterol; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Disease Models, Animal; Endothelial Cells; Glucose; Humans; Male; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Retina; Retinal Vessels; Streptozocin; Tyrosine; Vascular Endothelial Growth Factor A

2022
Role of the JAK/STAT pathway in a streptozotocin-induced diabetic retinopathy mouse model.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2022, Volume: 260, Issue:11

    Topics: Animals; Diabetes Mellitus; Diabetic Retinopathy; Disease Models, Animal; Glucose; Janus Kinase Inhibitors; Janus Kinases; Mice; Mice, Inbred C57BL; Phosphorylation; RNA, Messenger; Signal Transduction; STAT Transcription Factors; STAT5 Transcription Factor; Streptozocin; Tyrosine; Vascular Endothelial Growth Factor A

2022
The retinal tyrosine kinome of diabetic Akimba mice highlights potential for specific Src family kinase inhibition in retinal vascular disease.
    Experimental eye research, 2020, Volume: 197

    Topics: Animals; Blotting, Western; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Endothelial Cells; Male; Mice; Mice, Inbred C57BL; Signal Transduction; src-Family Kinases; Tyrosine

2020
Plasma phenylalanine and tyrosine and their interactions with diabetic nephropathy for risk of diabetic retinopathy in type 2 diabetes.
    BMJ open diabetes research & care, 2020, Volume: 8, Issue:1

    Topics: Diabetes Mellitus, Type 2; Diabetic Nephropathies; Diabetic Retinopathy; Humans; Phenylalanine; Tyrosine

2020
DNA Methylation-a Potential Source of Mitochondria DNA Base Mismatch in the Development of Diabetic Retinopathy.
    Molecular neurobiology, 2019, Volume: 56, Issue:1

    Topics: Animals; APOBEC Deaminases; Base Pair Mismatch; Base Sequence; Cytosine; Diabetic Retinopathy; DNA Methylation; DNA, Mitochondrial; Endothelial Cells; Humans; Mice, Inbred C57BL; Nucleic Acid Conformation; Peroxynitrous Acid; Superoxide Dismutase; Tyrosine

2019
MicroRNA-200b downregulates oxidation resistance 1 (Oxr1) expression in the retina of type 1 diabetes model.
    Investigative ophthalmology & visual science, 2013, Mar-05, Volume: 54, Issue:3

    Topics: Animals; Apoptosis; Cells, Cultured; Diabetes Mellitus, Type 1; Diabetic Retinopathy; Disease Models, Animal; Down-Regulation; Mice; Mice, Inbred C57BL; MicroRNAs; Oligonucleotide Array Sequence Analysis; Orexin Receptors; Oxidative Stress; Real-Time Polymerase Chain Reaction; Receptors, Neuropeptide; Retina; RNA, Messenger; Transfection; Tyrosine

2013
Oxidative stress-associated neuroretinal dysfunction and nitrosative stress in diabetic retinopathy.
    Canadian journal of diabetes, 2013, Volume: 37, Issue:6

    Topics: Adult; Case-Control Studies; Diabetic Retinopathy; Female; Glutamic Acid; Humans; Leukocytes, Mononuclear; Male; Malondialdehyde; Middle Aged; Nitrites; Oxidative Stress; Reactive Oxygen Species; Retina; Tyrosine; Vitreous Body

2013
Requirement of NOX2 expression in both retina and bone marrow for diabetes-induced retinal vascular injury.
    PloS one, 2013, Volume: 8, Issue:12

    Topics: Animals; Blood-Retinal Barrier; Bone Marrow; Cell Adhesion; Chimera; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Gene Expression; Genotype; Intercellular Adhesion Molecule-1; Leukocyte Common Antigens; Leukocytes; Male; Membrane Glycoproteins; Mice; Mice, Knockout; NADPH Oxidase 2; NADPH Oxidases; Oxidative Stress; Peroxynitrous Acid; Retina; Tyrosine; Vascular Endothelial Growth Factor A

2013
S-nitrosoglutathione inhibits inducible nitric oxide synthase upregulation by redox posttranslational modification in experimental diabetic retinopathy.
    Investigative ophthalmology & visual science, 2014, May-02, Volume: 55, Issue:5

    Topics: Analysis of Variance; Animals; Biomarkers; Cell Line; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Disease Models, Animal; Electroretinography; Glial Fibrillary Acidic Protein; Glutathione; Humans; Nitric Oxide Donors; Nitric Oxide Synthase Type II; Ophthalmic Solutions; Rats; Reactive Oxygen Species; Retina; S-Nitrosoglutathione; Tyrosine; Up-Regulation

2014
Melatonin prevents retinal oxidative stress and vascular changes in diabetic rats.
    Eye (London, England), 2014, Volume: 28, Issue:8

    Topics: Animals; Antioxidants; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetic Retinopathy; Enzyme-Linked Immunosorbent Assay; Eye Proteins; Hyperglycemia; Hypoxia-Inducible Factor 1, alpha Subunit; Injections, Intraperitoneal; Male; Malondialdehyde; Melatonin; Nerve Growth Factors; Oxidative Stress; Platelet Endothelial Cell Adhesion Molecule-1; Rats; Rats, Wistar; Retinal Vessels; Serpins; Tyrosine; Vascular Endothelial Growth Factor A

2014
Effect of obtusifolin administration on retinal capillary cell death and the development of retinopathy in diabetic rats.
    Cell biochemistry and biophysics, 2014, Volume: 70, Issue:3

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Administration, Oral; Animals; Anthraquinones; Antioxidants; Apoptosis; Capillaries; Deoxyguanosine; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Hyperglycemia; Male; NF-kappa B; Oxidative Stress; Rats; Rats, Wistar; Retina; Tyrosine

2014
Rapamycin inhibits oxidative and angiogenic mediators in diabetic retinopathy.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 2014, Volume: 49, Issue:5

    Topics: Angiogenesis Modulating Agents; Animals; Anti-Bacterial Agents; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Eye Proteins; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Malondialdehyde; Nerve Growth Factors; Oxidative Stress; Rats; Rats, Wistar; Serpins; Sirolimus; Tyrosine; Vascular Endothelial Growth Factor A

2014
Inhibition of retinopathy and retinal metabolic abnormalities in diabetic rats with AREDS-based micronutrients.
    Archives of ophthalmology (Chicago, Ill. : 1960), 2008, Volume: 126, Issue:9

    Topics: Animals; Ascorbic Acid; beta Carotene; Body Weight; Copper; Deoxyadenosines; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Diet; Eating; Electron Transport Complex III; Glycated Hemoglobin; Immunoenzyme Techniques; Male; Micronutrients; Nitric Oxide Synthase Type II; Oxidative Stress; Polymerase Chain Reaction; Rats; Rats, Inbred Lew; Retinal Vessels; RNA, Messenger; Superoxide Dismutase; Tyrosine; Vitamin E; Zinc Oxide

2008
p38MAPK and ERK promote nitric oxide production in cultured human retinal pigmented epithelial cells induced by high concentration glucose.
    Nitric oxide : biology and chemistry, 2009, Volume: 20, Issue:1

    Topics: Biomarkers; Cell Line; Diabetic Retinopathy; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Glucose; Humans; L-Lactate Dehydrogenase; Mitogen-Activated Protein Kinases; Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; p38 Mitogen-Activated Protein Kinases; Reactive Nitrogen Species; Reactive Oxygen Species; Retinal Pigment Epithelium; Superoxide Dismutase; Tyrosine

2009
Tyrosine phosphorylation of vitreous inflammatory and angiogenic peptides and proteins in diabetic retinopathy.
    Investigative ophthalmology & visual science, 2009, Volume: 50, Issue:3

    Topics: Angiogenesis Inducing Agents; Cytokines; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Eye Proteins; Humans; Immunoblotting; Inflammation Mediators; Male; Middle Aged; Peptides; Phosphorylation; Protein Array Analysis; Tyrosine; Vitrectomy; Vitreous Body

2009
Protective effects of a coumarin derivative in diabetic rats.
    Investigative ophthalmology & visual science, 2009, Volume: 50, Issue:8

    Topics: Animals; Antigens, CD; Blood-Retinal Barrier; Blotting, Western; Cadherins; Chromonar; Claudin-5; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Enzyme-Linked Immunosorbent Assay; Immunohistochemistry; Injections, Intraperitoneal; Intercellular Adhesion Molecule-1; Male; Membrane Proteins; Nitric Oxide Synthase Type III; Occludin; Phosphoproteins; Platelet Aggregation Inhibitors; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha; Tyrosine; Vascular Endothelial Growth Factor A; Zonula Occludens-1 Protein

2009
Attenuation of diabetes-induced renal dysfunction by multiple exposures to low-dose radiation is associated with the suppression of systemic and renal inflammation.
    American journal of physiology. Endocrinology and metabolism, 2009, Volume: 297, Issue:6

    Topics: Albuminuria; Aldehydes; Animals; Blotting, Western; Chemokine CCL2; Creatinine; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetic Retinopathy; Intercellular Adhesion Molecule-1; Interleukin-18; Male; Mice; Mice, Inbred C57BL; Nephritis; Random Allocation; Reverse Transcriptase Polymerase Chain Reaction; RNA; Serpin E2; Serpins; Tumor Necrosis Factor-alpha; Tyrosine

2009
Beneficial effect of docosahexanoic acid and lutein on retinal structural, metabolic, and functional abnormalities in diabetic rats.
    Current eye research, 2009, Volume: 34, Issue:11

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Apoptosis; Biomarkers; Blood Glucose; Caspase 3; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Docosahexaenoic Acids; Drug Therapy, Combination; Electroretinography; Enzyme-Linked Immunosorbent Assay; Fluorescent Antibody Technique, Indirect; Glutathione; Glutathione Peroxidase; In Situ Nick-End Labeling; Insulin; Lutein; Male; Malondialdehyde; Oxidative Stress; Rats; Rats, Wistar; Retina; Tyrosine

2009
IL-2 and IFN-gamma in the retina of diabetic rats.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2010, Volume: 248, Issue:7

    Topics: Animals; Cataract; Chemokines; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Disease Models, Animal; Interferon-gamma; Interleukin-10; Interleukin-1alpha; Interleukin-1beta; Interleukin-2; Interleukin-4; Interleukin-6; Interleukin-8; Male; Nitric Oxide; Rats; Rats, Long-Evans; Retina; T-Lymphocytes, Helper-Inducer; Tumor Necrosis Factor-alpha; Tyrosine

2010
Exogenous SOD mimetic tempol ameliorates the early retinal changes reestablishing the redox status in diabetic hypertensive rats.
    Investigative ophthalmology & visual science, 2010, Volume: 51, Issue:8

    Topics: Animals; Blotting, Western; Cyclic N-Oxides; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Fibronectins; Glial Fibrillary Acidic Protein; Glutathione; Hypertension; Immunoenzyme Techniques; Male; Neuroprotective Agents; Nitric Oxide Synthase Type II; Oxidation-Reduction; Oxidative Stress; Peroxynitrous Acid; Poly(ADP-ribose) Polymerases; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Spin Labels; Superoxide Dismutase; Tyrosine

2010
Reduction of inducible nitric oxide synthase via angiotensin receptor blocker prevents the oxidative retinal damage in diabetic hypertensive rats.
    Current eye research, 2010, Volume: 35, Issue:6

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Administration, Oral; Angiotensin II Type 1 Receptor Blockers; Animals; Biomarkers; Deoxyguanosine; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Down-Regulation; Losartan; Male; Nitrates; Nitric Oxide Synthase Type II; Nitrites; Osmolar Concentration; Oxidation-Reduction; Rats; Rats, Inbred SHR; Retina; Superoxide Dismutase; Tyrosine; Up-Regulation

2010
A potential role for angiopoietin 2 in the regulation of the blood-retinal barrier in diabetic retinopathy.
    Investigative ophthalmology & visual science, 2011, Jun-01, Volume: 52, Issue:6

    Topics: Angiopoietin-1; Angiopoietin-2; Animals; Antigens, CD; Blood-Retinal Barrier; Blotting, Western; Cadherins; Capillary Permeability; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Electric Impedance; Endothelium, Vascular; Fluorescent Antibody Technique, Indirect; Glucose; Humans; Hyperglycemia; Male; Phosphorylation; Rats; Rats, Sprague-Dawley; Retinal Vessels; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tyrosine; Up-Regulation

2011
Diabetic Retinopathy Is Associated with Decreased Tyrosine Nitrosylation of Vitreous Interleukins IL-1α, IL-1β, and IL-7.
    Ophthalmic research, 2011, Volume: 46, Issue:4

    Topics: Aged; Blood Glucose; Blotting, Western; Chromatography, High Pressure Liquid; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Female; Glycated Hemoglobin; Humans; Immunoprecipitation; Interleukin-1alpha; Interleukin-1beta; Interleukin-7; Male; Middle Aged; Nitric Oxide; Phosphorylation; Phosphotyrosine; Tyrosine; Vitreous Body

2011
Tyrosine nitration of prostacyclin synthase is associated with enhanced retinal cell apoptosis in diabetes.
    The American journal of pathology, 2011, Volume: 179, Issue:6

    Topics: Animals; Antioxidants; Apoptosis; Blood-Retinal Barrier; Cells, Cultured; Cyclic N-Oxides; Cyclooxygenase 2; Cytochrome P-450 Enzyme System; Diabetic Retinopathy; Glycation End Products, Advanced; Humans; Intramolecular Oxidoreductases; Lipoproteins, LDL; Mice; Mice, Inbred C57BL; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type II; Pericytes; Receptors, Thromboxane; Retina; Spin Labels; Superoxide Dismutase; Tight Junctions; Tyrosine

2011
Diabetes exacerbates retinal oxidative stress, inflammation, and microvascular degeneration in spontaneously hypertensive rats.
    Molecular vision, 2012, Volume: 18

    Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Gene Expression; Hypertension; Inflammation; Intercellular Adhesion Molecule-1; Lipid Peroxidation; Male; MAP Kinase Kinase 4; NF-kappa B; Oxidative Stress; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Retina; Retinal Neovascularization; Tumor Necrosis Factor-alpha; Tyrosine

2012
Effect of reinstitution of good glycemic control on retinal oxidative stress and nitrative stress in diabetic rats.
    Diabetes, 2003, Volume: 52, Issue:3

    Topics: Animals; Blood Glucose; Diabetes Mellitus; Diabetic Retinopathy; Glutathione; Hyperglycemia; Insulin; Lipid Peroxides; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxidative Stress; Rats; Rats, Wistar; Retina; Tyrosine

2003
Diabetes-induced activation of nuclear transcriptional factor in the retina, and its inhibition by antioxidants.
    Free radical research, 2003, Volume: 37, Issue:11

    Topics: alpha-Tocopherol; Animals; Antioxidants; Ascorbic Acid; beta Carotene; Chromans; Cysteine; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Glucose; Lipid Peroxides; Male; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Rats; Rats, Sprague-Dawley; Retina; Selenium; Tyrosine

2003
[The effect of nitrogen monoxide and its synthase on the diabetic retinal damage].
    [Zhonghua yan ke za zhi] Chinese journal of ophthalmology, 2005, Volume: 41, Issue:9

    Topics: Animals; Diabetic Retinopathy; Immunohistochemistry; Male; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Rats; Rats, Sprague-Dawley; Retinal Ganglion Cells; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tyrosine

2005
Role of mitochondrial superoxide dismutase in the development of diabetic retinopathy.
    Investigative ophthalmology & visual science, 2006, Volume: 47, Issue:4

    Topics: Animals; Apoptosis; Cattle; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Endothelium, Vascular; Gene Expression Regulation, Enzymologic; Guanosine; Mitochondria; Nitrosation; Oxidative Stress; Rats; Rats, Wistar; Retina; Retinal Vessels; RNA, Messenger; Superoxide Dismutase; Transfection; Tyrosine

2006
Hrs is a positive regulator of VEGF and insulin signaling.
    Experimental cell research, 2007, May-15, Volume: 313, Issue:9

    Topics: Binding Sites; Cell Line; Diabetic Retinopathy; Endosomal Sorting Complexes Required for Transport; Gene Expression Regulation; GRB10 Adaptor Protein; Humans; Insulin; Nedd4 Ubiquitin Protein Ligases; Neovascularization, Pathologic; Phosphoproteins; Phosphorylation; Protein Structure, Tertiary; Receptor, Insulin; Signal Transduction; Tyrosine; Ubiquitin; Ubiquitin-Protein Ligases; Up-Regulation; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2

2007
Arterial hypertension exacerbates oxidative stress in early diabetic retinopathy.
    Free radical research, 2007, Volume: 41, Issue:10

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Antioxidants; Deoxyguanosine; Diabetic Retinopathy; DNA Damage; Glutathione; Hypertension; Male; Nitrogen; Oxidative Stress; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Superoxide Dismutase; Tyrosine

2007
Targets of tyrosine nitration in diabetic rat retina.
    Molecular & cellular proteomics : MCP, 2008, Volume: 7, Issue:5

    Topics: Amino Acid Sequence; Animals; Blotting, Western; Diabetic Retinopathy; Electrophoresis, Polyacrylamide Gel; Glucose Transporter Type 4; Immunoprecipitation; Male; Molecular Sequence Data; Nitrogen; Phosphorylation; Phosphotyrosine; Protein Structure, Tertiary; Protein Tyrosine Phosphatases; Proteins; Rats; Rats, Sprague-Dawley; Receptor, Fibroblast Growth Factor, Type 2; Tyrosine; Vesicular Transport Proteins

2008
Beneficial effect of zeaxanthin on retinal metabolic abnormalities in diabetic rats.
    Investigative ophthalmology & visual science, 2008, Volume: 49, Issue:4

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Blood Glucose; Deoxyguanosine; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Diet; Electron Transport Complex III; Intercellular Adhesion Molecule-1; Male; Nitric Oxide Synthase Type II; Oxidative Stress; Rats; Rats, Inbred Lew; RNA, Messenger; Superoxide Dismutase; Tyrosine; Vascular Endothelial Growth Factor A; Xanthophylls; Zeaxanthins

2008
Aldose reductase inhibitor fidarestat counteracts diabetes-associated cataract formation, retinal oxidative-nitrosative stress, glial activation, and apoptosis.
    International journal of molecular medicine, 2008, Volume: 21, Issue:6

    Topics: Aldehyde Reductase; Animals; Apoptosis; Apoptosis Regulatory Proteins; bcl-2-Associated X Protein; Blood Glucose; Blotting, Western; Cataract; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Glial Fibrillary Acidic Protein; Imidazolidines; Immunohistochemistry; In Situ Nick-End Labeling; Neuroglia; Ophthalmoscopy; Oxidative Stress; Poly(ADP-ribose) Polymerases; Rats; Retina; Streptozocin; Tyrosine

2008
Diabetes-induced nitrative stress in the retina, and correction by aminoguanidine.
    Journal of neurochemistry, 2002, Volume: 80, Issue:5

    Topics: Animals; Cattle; Cells, Cultured; Cyclic GMP; Diabetes Complications; Diabetes Mellitus; Diabetic Retinopathy; Endothelium, Vascular; Glucose; Guanidines; Hyperglycemia; Immunohistochemistry; Male; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxidative Stress; Peroxynitrous Acid; Rats; Rats, Sprague-Dawley; Retina; Streptozocin; Tyrosine

2002
Inducible nitric oxide synthase mediates retinal apoptosis in ischemic proliferative retinopathy.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2002, May-15, Volume: 22, Issue:10

    Topics: Aging; Amidines; Animals; Animals, Newborn; Apoptosis; Benzylamines; Cell Count; Crosses, Genetic; Diabetic Retinopathy; Disease Models, Animal; Drug Administration Routes; Enzyme Inhibitors; Immunohistochemistry; In Situ Nick-End Labeling; Ischemia; Mice; Mice, Inbred Strains; Mice, Knockout; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxygen; Proteins; Retina; Retinal Diseases; Retinal Vein Occlusion; Tyrosine

2002
Alterations in the retinal dopaminergic neuronal system in rats with streptozotocin-induced diabetes.
    Journal of neurochemistry, 1985, Volume: 45, Issue:2

    Topics: 3,4-Dihydroxyphenylacetic Acid; Animals; Cattle; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Dihydroxyphenylalanine; Dopamine; Glucose; Male; Neurons; Rats; Rats, Inbred Strains; Retina; Spiperone; Tyrosine

1985