Compounds > tyrosine

tyrosine and Diabetes Mellitus, Type 1

tyrosine has been researched along with Diabetes Mellitus, Type 1 in 63 studies

Research

Studies (63)

TimeframeStudies, this research(%)All Research%
pre-19904 (6.35)18.7374
1990's12 (19.05)18.2507
2000's22 (34.92)29.6817
2010's21 (33.33)24.3611
2020's4 (6.35)2.80

Authors

AuthorsStudies
Kim, JH; Kim, KY; Kim, MS; Lee, SY; Lee, YA; Lee, YJ; Shin, CH1
Buzzetti, R; D'Onofrio, L; Maddaloni, E; Panimolle, F; Tiberti, C; Zampetti, S1
Ding, Y; Jiang, W; Liu, Z; Luo, S; Weng, J; Xu, M; Xu, W; Yan, J; Yang, D; Yue, T; Zheng, X1
Iamsaard, S; Yannasithinon, S1
Arzhanova, O; Chepanov, S; Kapustin, R; Kopteeva, E1
Roth, J; Taatjes, DJ1
El Fotoh, WMMA; El Razek Midan, DA; El Shalakany, AH1
Bae, SS; Ha, HK; Han, M; Jung, ES; Kim, IY; Kim, SS; Lee, DW; Lee, HW; Lee, MY; Lee, SB; Lovett, DH; Rhee, H; Seong, EY; Song, SH1
Chen, Q; Ma, JX; Murray, AR; Park, K; Takahashi, Y; Zhou, KK1
Lupachyk, S; Obrosov, A; Obrosova, IG; Shevalye, H; Vareniuk, I; Watcho, P; Yorek, MA1
Bucciarelli, L; Canivell, S; Ceriello, A; Genovese, S; La Sala, L; Novials, A; Ortega, E; Pujadas, G; Rondinelli, M1
Chen, C; Cheung, CW; Irwin, MG; Li, H; Liu, Z; Wang, J; Wong, GT; Xia, Z; Zhang, L1
Alexander, JJ; Amick, MA; Atkinson, M; Belkin, NS; Carter, J; Clare-Salzler, MJ; Garrigan, E; Han, Z; Litherland, SA; Seydel, F; Wasserfall, C1
Bauer, JA; Cook, AC; Joshi, MS; Mihm, MJ; Schanbacher, BL1
Bakariş, S; Durdu, H; Ergün, Y; Ganiyusufoğlu, E; Kılınç, M; Ozdemir, G1
Barnucz, E; Gwanmesia, PN; Hirschberg, K; Korkmaz, S; Li, S; Loganathan, S; Mátyás, C; Merkely, B; Németh, BT; Oláh, A; Páli, S; Radovits, T; Szabó, G; Zubarevich, A1
Chen, J; Feng, W; Li, X; Lu, X; Tan, Y; Yan, X; Zeng, J; Zhang, C; Zhang, Z; Zhou, S1
Amirapu, S; Dahl-Jørgensen, K; Farik, S; Krogvold, L; Martin, C; Reddy, S; Wu, F1
Baliga, R; Bauer, JA; Giannone, PJ; Han, B; Huang, H1
Cai, L; Guo, W; Ji, S; Li, C; Li, X; Tan, Y; Zhang, C1
Messina, LM; Nowicki, PT; Park, B; Tie, G; Yan, J; Yan, Y1
Andjelkovic, AV; Hoffman, WH; Passmore, GG; Sima, AA; Zhang, W1
Chiu, WC; Liu, JJ; Pai, MH; Tsai, PH; Yeh, SL1
Fenoy, FJ; Hernandez, I; Li Volti, G; Lopez, B; Perez, C; Rodriguez, F; Salom, MG; Stec, DE1
Lai, CY; Lin, SY; Miaw, SC; Sytwu, HK; Wu, CK; Yeh, LT1
An, Y; Chen, AF; Fan, S; Han, J; Li, X; Liu, S; Tie, L; Xiao, Y; Xiaokaiti, Y1
Aoki, Y; Carmines, PK; Ichikawa, T; Ikenagasa, H; Imaizumi, H; Ishii, N; Katagiri, M; Kodera, Y; Maeda, T; Oh-Ishi, M; Takenaka, T; Yokoba, M1
Andersson, S; Arduini, A; Asensi, MA; Cubells, E; Escobar, J; Sastre, J; Stefanovic, V; Teramo, K; Vento, M1
Bryner, KD; Christie, I; Ganser, G; Hobbs, GR; Hoeldtke, RD; McNeill, DR; Riggs, JE; Van Dyke, K; Warehime, SS1
Koo, JR; Vaziri, ND1
Bryner, KD; Hobbs, G; Hoeldtke, RD; McNeill, DR; Van Dyke, K; Warehime, SS1
Cetkovic-Cvrlje, M; Dragt, AL; Liu, XP; Uckun, FM; Vassilev, A1
Bassett, ML; Cadet, E; Carter, K; David, V; Jouanolle, AM; Livesey, KJ; Merryweather-Clarke, AT; Mosser, A; Pointon, JJ; Poulton, J; Roberts, AG; Robson, KJ; Rochette, J; Wimhurst, VL; Worwood, M1
Bradley, B; Haskins, K; Kench, J; McDuffie, M; Powers, K; Pugazhenthi, S; Reusch, J1
Auricchio, A; Beguinot, F; Cotugno, G; Formisano, P; Linher, K; Pollock, R1
Abatan, OI; Charniauskaya, T; Groves, JT; Mabley, JG; Obrosova, IG; Szabó, C; Zsengellér, Z1
Ceriello, A; Gloster, MA; Maggs, DG; Piconi, L; Quagliaro, L; Ruggles, JA; Schnabel, CA; Wang, Y; Weyer, C1
Cota-Gomez, A; Flores, NC; Flores, SC; Haskins, K; Hernandez-Saavedra, D; Kench, J; Ling, X; Marecki, JC; McCord, JM; McDuffie, M; McMurtry, I; Oka, M; Powers, K1
Andrews, JC; Jensen, MD; Moller, N; Nair, KS; Rizza, RA1
Al-Abed, Y; Harhaji, L; Maksimovic-Ivanic, D; Mangano, K; Metz, C; Miljkovic, D; Momcilovic, M; Nicoletti, F; Papaccio, G; Popadic, D; Stojanovic, I; Stosic-Grujicic, S1
Backer, JM; Folli, F; Kahn, CR; Saad, MJ1
Ekberg, K; Fernqvist-Forbes, E; Ford, GC; Nair, KS; Wahren, J1
Cardoso, AI; Llera, AS; Poskus, E; Stumpo, RR1
Delovitch, TL; Jaramillo, A; Lazarus, AH; Rapoport, MJ; Speck, E1
Rabinovitch, A; Suarez-Pinzon, WL; Szabó, C1
Arreaza, G; Cameron, M; Delovitch, TL; Gill, B; Ochi, A; Salojin, K; Zhang, J1
Birnbacher, R; Herkner, K; Kampel, D; Krapfenbauer, K; Lubec, G; Vierhapper, H1
Brockman, DE; Eis, AL; Gibson, JL; Greer, IA; Lyall, F; Myatt, L1
Hermon, M; Hoeger, H; Lubec, B; Lubec, G1
Ahuja, S; Carter, R; Gerstein, HC; Kwan, T; Leber, B1
Ekberg, K; Meek, SE; Moller, N; Nair, KS; Short, KR1
Amati, S; Biagini, G; D'Aurelio, M; Mazzanti, L; Pugnaloni, A; Rabini, RA; Sgarbi, G; Tesei, M1
Brockman, D; Eis, A; Kossenjans, W; Myatt, L; Sahay, R1
Cakatay, U; Salman, S; Satman, L; Sivas, A; Telci, A1
Cakatay, U; Salman, S; Satman, I; Sivas, A; Telci, A1
Eis, AL; Myatt, L; Stanek, J1
Bian, KA; Carmines, PK; Ishii, N; Lane, PH; Murad, F; Patel, KP; Pollock, JS; Taylor, T1
Horio, F; Kato, Y; Naito, M; Nomura, H; Osawa, T; Toyokuni, S; Tsuda, T; Uchida, K; Ueno, Y1
Beller, D; Liu, J1
Centerwall, WR; Chinnock, RF; Goodman, SI; Mace, JW1
Diaz, JL; Wilkin, TJ1
Ballester Galindo, I; Campello Oltra, MJ; Clemente Yago, F; Cortés Castell, E; Herrero Galiana, A; Moya Benavent, M1
de Lange, WE; Doorenbos, H; Visser, JW1

Reviews

1 review(s) available for tyrosine and Diabetes Mellitus, Type 1

ArticleYear
Role for oxidative stress in the regeneration of islet beta cells?
    Journal of investigative medicine : the official publication of the American Federation for Clinical Research, 2004, Volume: 52, Issue:1

    Topics: Animals; Cell Division; Diabetes Mellitus, Type 1; Humans; Islets of Langerhans; Mice; Mice, Congenic; Mice, Inbred NOD; Oxidative Stress; Regeneration; Tyrosine

2004

Trials

2 trial(s) available for tyrosine and Diabetes Mellitus, Type 1

ArticleYear
Vitamin C further improves the protective effect of GLP-1 on the ischemia-reperfusion-like effect induced by hyperglycemia post-hypoglycemia in type 1 diabetes.
    Cardiovascular diabetology, 2013, Jun-27, Volume: 12

    Topics: Adult; Antioxidants; Ascorbic Acid; Biomarkers; Blood Glucose; Diabetes Mellitus, Type 1; Dinoprost; Female; Glucagon-Like Peptide 1; Humans; Hyperglycemia; Hypoglycemia; Hypoglycemic Agents; Inflammation; Inflammation Mediators; Infusions, Parenteral; Intercellular Adhesion Molecule-1; Interleukin-6; Male; Oxidative Stress; Reperfusion Injury; Time Factors; Treatment Outcome; Tyrosine; Vasodilation; Young Adult

2013
Effects of pramlintide on postprandial glucose excursions and measures of oxidative stress in patients with type 1 diabetes.
    Diabetes care, 2005, Volume: 28, Issue:3

    Topics: Adult; Amyloid; Blood Glucose; Cross-Over Studies; Diabetes Mellitus, Type 1; Enzyme-Linked Immunosorbent Assay; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Islet Amyloid Polypeptide; Lipoproteins, LDL; Male; Middle Aged; Oxidative Stress; Placebos; Postprandial Period; Safety; Single-Blind Method; Tyrosine

2005

Other Studies

60 other study(ies) available for tyrosine and Diabetes Mellitus, Type 1

ArticleYear
Glutamic Acid Decarboxylase and Tyrosine Phosphatase-Related Islet Antigen-2 Positivity among Children and Adolescents with Diabetes in Korea.
    Diabetes & metabolism journal, 2022, Volume: 46, Issue:6

    Topics: Adolescent; Autoantibodies; Child; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Glutamate Decarboxylase; Humans; Insulin; Republic of Korea; Retrospective Studies; Tyrosine

2022
Immunoreactivities Against Different Tyrosine-Phosphatase 2 (IA-2)(256-760) Protein Domains Characterize Distinct Phenotypes in Subjects With LADA.
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: Autoantibodies; Diabetes Mellitus, Type 1; Epitopes; Humans; Immunity; Latent Autoimmune Diabetes in Adults; Obesity; Phenotype; Phosphoric Monoester Hydrolases; Protein Domains; Tyrosine

2022
Gut microbiome and metabolic activity in type 1 diabetes: An analysis based on the presence of GADA.
    Frontiers in endocrinology, 2022, Volume: 13

    Topics: Antibodies; Diabetes Mellitus, Type 1; Gastrointestinal Microbiome; Glutamate Decarboxylase; Humans; Phenylalanine; RNA, Ribosomal, 16S; Tryptophan; Tyrosine

2022
Alterations of morphology and phosphorylated protein expression in the seminal vesicles of diabetic mice.
    Andrologia, 2019, Volume: 51, Issue:10

    Topics: Animals; Citric Acid; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Fructosamine; Humans; Infertility, Male; Magnesium; Male; Mice; Mice, Inbred C57BL; Phosphorylation; Seminal Vesicles; Streptozocin; Tyrosine

2019
Maternal serum nitrotyrosine, 8-isoprostane and total antioxidant capacity levels in pre-gestational or gestational diabetes mellitus.
    Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2020, Volume: 36, Issue:sup1

    Topics: Adult; Antioxidants; Case-Control Studies; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetes, Gestational; Dinoprost; Female; Humans; Pre-Eclampsia; Pregnancy; Pregnancy in Diabetics; Pregnancy Outcome; Russia; Tyrosine

2020
 In focus in HCB.
    Histochemistry and cell biology, 2017, Volume: 147, Issue:5

    Topics: Diabetes Mellitus, Type 1; Humans; Islets of Langerhans; Tyrosine

2017
Role of C1858T Polymorphism of Lymphoid Tyrosine Phosphatase in Egyptian Children and Adolescents with Type 1 Diabetes.
    Current diabetes reviews, 2019, Volume: 16, Issue:1

    Topics: Adolescent; Case-Control Studies; Child; Diabetes Mellitus, Type 1; Egypt; Female; Genetic Predisposition to Disease; Humans; Polymorphism, Single Nucleotide; Protein Tyrosine Phosphatase, Non-Receptor Type 22; Tyrosine

2019
The two isoforms of matrix metalloproteinase- 2 have distinct renal spatial and temporal distributions in murine models of types 1 and 2 diabetes mellitus.
    BMC nephrology, 2018, 09-25, Volume: 19, Issue:1

    Topics: Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Disease Models, Animal; Isoenzymes; Kidney; Kidney Cortex; Kidney Medulla; Kidney Tubules; Male; Matrix Metalloproteinase 2; Mice; Mice, Inbred C57BL; Oxidative Stress; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tyrosine; Up-Regulation

2018
MicroRNA-200b downregulates oxidation resistance 1 (Oxr1) expression in the retina of type 1 diabetes model.
    Investigative ophthalmology & visual science, 2013, Mar-05, Volume: 54, Issue:3

    Topics: Animals; Apoptosis; Cells, Cultured; Diabetes Mellitus, Type 1; Diabetic Retinopathy; Disease Models, Animal; Down-Regulation; Mice; Mice, Inbred C57BL; MicroRNAs; Oligonucleotide Array Sequence Analysis; Orexin Receptors; Oxidative Stress; Real-Time Polymerase Chain Reaction; Receptors, Neuropeptide; Retina; RNA, Messenger; Transfection; Tyrosine

2013
Na+/H+ exchanger 1 inhibition reverses manifestation of peripheral diabetic neuropathy in type 1 diabetic rats.
    American journal of physiology. Endocrinology and metabolism, 2013, Aug-01, Volume: 305, Issue:3

    Topics: Aldehydes; Animals; Arterioles; Behavior, Animal; Blood Glucose; Blotting, Western; Body Weight; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetic Neuropathies; Glycation End Products, Advanced; Guanidines; Male; Nerve Fibers; Nitrates; Pain Measurement; Pyruvaldehyde; Rats; Rats, Wistar; Reduced Folate Carrier Protein; Sciatic Nerve; Skin; Sulfones; Superoxides; Tyrosine

2013
Susceptibility to myocardial ischemia reperfusion injury at early stage of type 1 diabetes in rats.
    Cardiovascular diabetology, 2013, Sep-17, Volume: 12

    Topics: Animals; Biomarkers; Caspase 3; Creatine Kinase, BB Form; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Dinoprost; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; L-Lactate Dehydrogenase; Male; Myocardial Contraction; Myocardial Infarction; Myocardial Reperfusion; Myocardial Reperfusion Injury; Myocardium; Nitric Oxide; Oxidative Stress; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats; Rats, Sprague-Dawley; Severity of Illness Index; STAT3 Transcription Factor; Stroke Volume; Superoxide Dismutase; Time Factors; Tumor Necrosis Factor-alpha; Tyrosine; Ventricular Function, Left; Ventricular Pressure

2013
Persistent STAT5 phosphorylation and epigenetic dysregulation of GM-CSF and PGS2/COX2 expression in Type 1 diabetic human monocytes.
    PloS one, 2013, Volume: 8, Issue:10

    Topics: Acetylation; Adolescent; Adult; Aged; Base Sequence; Cells, Cultured; Child; Cyclooxygenase 2; Diabetes Mellitus, Type 1; Epigenesis, Genetic; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Histones; Humans; Male; Middle Aged; Molecular Sequence Data; Monocytes; Phosphorylation; Protein Binding; Regulatory Sequences, Nucleic Acid; Sequence Homology, Nucleic Acid; STAT5 Transcription Factor; Tyrosine; Young Adult

2013
Alterations in connexin 43 during diabetic cardiomyopathy: competition of tyrosine nitration versus phosphorylation.
    Journal of diabetes, 2015, Volume: 7, Issue:2

    Topics: Animals; Blotting, Western; Connexin 43; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetic Cardiomyopathies; Electrophysiology; Hyperglycemia; Immunoenzyme Techniques; Immunoprecipitation; Male; Nitrogen; Oxidative Stress; Phosphorylation; Rats; Rats, Sprague-Dawley; Tyrosine

2015
Melatonin prevents retinal oxidative stress and vascular changes in diabetic rats.
    Eye (London, England), 2014, Volume: 28, Issue:8

    Topics: Animals; Antioxidants; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetic Retinopathy; Enzyme-Linked Immunosorbent Assay; Eye Proteins; Hyperglycemia; Hypoxia-Inducible Factor 1, alpha Subunit; Injections, Intraperitoneal; Male; Malondialdehyde; Melatonin; Nerve Growth Factors; Oxidative Stress; Platelet Endothelial Cell Adhesion Molecule-1; Rats; Rats, Wistar; Retinal Vessels; Serpins; Tyrosine; Vascular Endothelial Growth Factor A

2014
An altered pattern of myocardial histopathological and molecular changes underlies the different characteristics of type-1 and type-2 diabetic cardiac dysfunction.
    Journal of diabetes research, 2015, Volume: 2015

    Topics: Animals; Apoptosis; Diabetes Complications; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Fibrosis; Gene Expression Regulation; Heart; Heart Diseases; Hemodynamics; Immunohistochemistry; In Situ Nick-End Labeling; Male; Myocardium; Oxidative Stress; Rats; Rats, Sprague-Dawley; Rats, Zucker; RNA, Messenger; Transforming Growth Factor beta1; Tyrosine; Ventricular Function, Left

2015
Fibroblast growth factor 21 deletion aggravates diabetes-induced pathogenic changes in the aorta in type 1 diabetic mice.
    Cardiovascular diabetology, 2015, 06-11, Volume: 14, Issue:1

    Topics: Aldehydes; Animals; Aorta; Aortic Diseases; Apoptosis; Collagen; Connective Tissue Growth Factor; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Fibroblast Growth Factors; Fibrosis; Gene Deletion; Genetic Predisposition to Disease; Male; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide Synthase Type III; Oxidative Stress; Phenotype; Signal Transduction; Time Factors; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha; Tyrosine; Vascular Remodeling

2015
An immunohistochemical study of nitrotyrosine expression in pancreatic islets of cases with increasing duration of type 1 diabetes and without diabetes.
    Histochemistry and cell biology, 2017, Volume: 147, Issue:5

    Topics: Adolescent; Adult; Child; Child, Preschool; Diabetes Mellitus, Type 1; Female; Humans; Immunohistochemistry; Islets of Langerhans; Male; Tyrosine; Young Adult

2017
Decreased cardiac expression of vascular endothelial growth factor and redox imbalance in murine diabetic cardiomyopathy.
    American journal of physiology. Heart and circulatory physiology, 2009, Volume: 297, Issue:2

    Topics: Animals; Cardiomyopathies; Coronary Circulation; Diabetes Complications; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Disease Models, Animal; Glutathione; Glutathione Disulfide; Hyperglycemia; Male; Mice; Mice, Inbred Strains; Microcirculation; Myocardium; Oxidants; Oxidation-Reduction; Specific Pathogen-Free Organisms; Stroke Volume; Tyrosine; Vascular Endothelial Growth Factor A; Ventricular Function, Left

2009
Attenuation of diabetes-induced renal dysfunction by multiple exposures to low-dose radiation is associated with the suppression of systemic and renal inflammation.
    American journal of physiology. Endocrinology and metabolism, 2009, Volume: 297, Issue:6

    Topics: Albuminuria; Aldehydes; Animals; Blotting, Western; Chemokine CCL2; Creatinine; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetic Retinopathy; Intercellular Adhesion Molecule-1; Interleukin-18; Male; Mice; Mice, Inbred C57BL; Nephritis; Random Allocation; Reverse Transcriptase Polymerase Chain Reaction; RNA; Serpin E2; Serpins; Tumor Necrosis Factor-alpha; Tyrosine

2009
Recovery from hind limb ischemia is less effective in type 2 than in type 1 diabetic mice: roles of endothelial nitric oxide synthase and endothelial progenitor cells.
    Journal of vascular surgery, 2009, Volume: 50, Issue:6

    Topics: Animals; Blood Glucose; Body Weight; Chemotaxis; Collateral Circulation; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Endothelial Cells; Hindlimb; Ischemia; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Muscle, Skeletal; Neovascularization, Physiologic; Nitric Oxide Synthase Type III; Oxidative Stress; Receptors, Leptin; Recovery of Function; Regional Blood Flow; Stem Cells; Time Factors; Tyrosine; Vascular Endothelial Growth Factor A

2009
Insulin and IGF-1 receptors, nitrotyrosin and cerebral neuronal deficits in two young patients with diabetic ketoacidosis and fatal brain edema.
    Brain research, 2010, Jul-09, Volume: 1343

    Topics: Adolescent; Biomarkers; Brain Edema; Diabetes Mellitus, Type 1; Diabetic Ketoacidosis; Disease Progression; Fatal Outcome; Female; Humans; Insulin; Receptor, IGF Type 1; Tyrosine

2010
Effects of dietary glutamine on adhesion molecule expression and oxidative stress in mice with streptozotocin-induced type 1 diabetes.
    Clinical nutrition (Edinburgh, Scotland), 2011, Volume: 30, Issue:1

    Topics: Analysis of Variance; Animals; Blood Glucose; Cell Adhesion Molecules; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diet; Dietary Supplements; Fructosamine; Glutamine; Glutathione; Insulin; Insulin Secretion; Leukocytes; Male; Mice; Mice, Inbred ICR; Oxidative Stress; Streptozocin; Tyrosine

2011
Chronic tempol treatment attenuates the renal hemodynamic effects induced by a heme oxygenase inhibitor in streptozotocin diabetic rats.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2011, Volume: 301, Issue:5

    Topics: Animals; Antioxidants; Boranes; Carbon Monoxide; Carbonates; Cyclic N-Oxides; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Dose-Response Relationship, Drug; Enzyme Inhibitors; Heme Oxygenase (Decyclizing); Hemodynamics; Kidney; Male; Metalloporphyrins; Nitric Oxide; Oxidative Stress; Rats; Rats, Sprague-Dawley; Renal Circulation; Spin Labels; Time Factors; Tyrosine; Vasoconstriction; Vasodilation

2011
Tyrosine phosphorylation of c-Maf enhances the expression of IL-4 gene.
    Journal of immunology (Baltimore, Md. : 1950), 2012, Aug-15, Volume: 189, Issue:4

    Topics: Animals; Blotting, Western; Diabetes Mellitus, Type 1; Female; Gene Expression Regulation; HEK293 Cells; Humans; Immunoprecipitation; Interleukin-4; Mice; Mice, Inbred NOD; Microscopy, Confocal; Phosphorylation; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-maf; Real-Time Polymerase Chain Reaction; Th2 Cells; Transfection; Tyrosine

2012
Genistein accelerates refractory wound healing by suppressing superoxide and FoxO1/iNOS pathway in type 1 diabetes.
    The Journal of nutritional biochemistry, 2013, Volume: 24, Issue:1

    Topics: Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Forkhead Box Protein O1; Forkhead Transcription Factors; Genistein; Human Umbilical Vein Endothelial Cells; Humans; Male; Mice; Mice, Inbred C57BL; Nitric Oxide Synthase Type II; Oxidative Stress; Sirtuin 1; Streptozocin; Superoxides; Tyrosine; Wound Healing

2013
Angiotensin-converting enzyme inhibition curbs tyrosine nitration of mitochondrial proteins in the renal cortex during the early stage of diabetes mellitus in rats.
    Clinical science (London, England : 1979), 2013, Volume: 124, Issue:8

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Diabetes Mellitus, Type 1; Disease Models, Animal; Humans; Kidney Cortex; Male; Mitochondrial Proteins; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Tyrosine

2013
Amniotic fluid oxidative and nitrosative stress biomarkers correlate with fetal chronic hypoxia in diabetic pregnancies.
    Neonatology, 2013, Volume: 103, Issue:3

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Adult; Amniocentesis; Amniotic Fluid; Biomarkers; Birth Weight; Chromatography, High Pressure Liquid; Chronic Disease; Deoxyguanosine; Diabetes Mellitus, Type 1; Diabetes, Gestational; Erythropoietin; Female; Fetal Hypoxia; Gestational Age; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Immunoassay; Infant, Newborn; Insulin; Male; Nitrosation; Oxidative Stress; Pilot Projects; Pregnancy; Pregnancy in Diabetics; Tandem Mass Spectrometry; Tyrosine; Young Adult

2013
Nitrosative stress, uric Acid, and peripheral nerve function in early type 1 diabetes.
    Diabetes, 2002, Volume: 51, Issue:9

    Topics: Adolescent; Adult; Autonomic Nervous System; Child; Diabetes Mellitus, Type 1; Dinoprost; F2-Isoprostanes; Female; Heart Conduction System; Humans; Male; Motor Neurons; Neural Conduction; Nitrates; Nitrites; Peripheral Nerves; Peroxynitrous Acid; Reference Values; Sweating; Time Factors; Tyrosine; Uric Acid

2002
Effects of diabetes, insulin and antioxidants on NO synthase abundance and NO interaction with reactive oxygen species.
    Kidney international, 2003, Volume: 63, Issue:1

    Topics: Animals; Antioxidants; Blood Pressure; Diabetes Mellitus, Type 1; Diabetic Nephropathies; Insulin; Lysine; Male; Malondialdehyde; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Tyrosine

2003
Oxidative stress and insulin requirements in patients with recent-onset type 1 diabetes.
    The Journal of clinical endocrinology and metabolism, 2003, Volume: 88, Issue:4

    Topics: Adolescent; Adult; Child; Diabetes Mellitus, Type 1; Dinoprost; F2-Isoprostanes; Female; Glycated Hemoglobin; Humans; Insulin; Islets of Langerhans; Longitudinal Studies; Male; Nitrates; Nitrites; Oxidative Stress; Tyrosine

2003
Targeting JAK3 with JANEX-1 for prevention of autoimmune type 1 diabetes in NOD mice.
    Clinical immunology (Orlando, Fla.), 2003, Volume: 106, Issue:3

    Topics: Adoptive Transfer; Animals; Cytokines; Diabetes Mellitus, Type 1; DNA-Binding Proteins; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Interleukin-2; Janus Kinase 3; Lymphocyte Activation; Mice; Mice, Inbred C57BL; Mice, Inbred NOD; Milk Proteins; Ovalbumin; Phosphorylation; Protein-Tyrosine Kinases; Quinazolines; STAT5 Transcription Factor; T-Lymphocytes; Trans-Activators; Tyrosine

2003
The 16189 variant of mitochondrial DNA occurs more frequently in C282Y homozygotes with haemochromatosis than those without iron loading.
    Journal of medical genetics, 2004, Volume: 41, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Amino Acid Substitution; Cohort Studies; Cysteine; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; DNA, Mitochondrial; Gene Frequency; Genotype; Hemochromatosis; Hemochromatosis Protein; Histocompatibility Antigens Class I; Homozygote; Humans; Iron Overload; Membrane Proteins; Middle Aged; Mutation; Phenotype; Tyrosine

2004
Pharmacological regulation of the insulin receptor signaling pathway mimics insulin action in cells transduced with viral vectors.
    Human gene therapy, 2004, Volume: 15, Issue:11

    Topics: Blotting, Western; Cell Line; Cell Line, Tumor; Cell Proliferation; Dependovirus; Diabetes Mellitus, Type 1; Dimerization; Dose-Response Relationship, Drug; Fibroblasts; Gene Transfer Techniques; Genetic Vectors; Glycogen Synthase; Homozygote; Humans; Immunoprecipitation; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Mutation; Phosphoproteins; Phosphorylation; Protein Structure, Tertiary; Receptor, Insulin; Signal Transduction; Tacrolimus; Time Factors; Tyrosine

2004
Role for nitrosative stress in diabetic neuropathy: evidence from studies with a peroxynitrite decomposition catalyst.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2005, Volume: 19, Issue:3

    Topics: Animals; Blood Glucose; Creatine; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetic Neuropathies; Metalloporphyrins; Mice; Mice, Inbred NOD; Neural Conduction; Neurons, Afferent; Oxidative Stress; Peroxynitrous Acid; Phosphocreatine; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerases; Reactive Nitrogen Species; Sciatic Nerve; Tyrosine; Weight Gain

2005
Alterations in redox homeostasis and prostaglandins impair endothelial-dependent vasodilation in euglycemic autoimmune nonobese diabetic mice.
    Free radical biology & medicine, 2005, Oct-15, Volume: 39, Issue:8

    Topics: Acetophenones; Acetylcholine; Animals; Aorta; Cyclooxygenase Inhibitors; Diabetes Mellitus, Type 1; Endothelium, Vascular; Homeostasis; Mice; Mice, Inbred BALB C; Mice, Inbred NOD; NADPH Oxidases; Nitric Oxide; Onium Compounds; Oxidation-Reduction; Oxidative Stress; Prediabetic State; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Receptors, Thromboxane A2, Prostaglandin H2; Tyrosine; Vasodilation

2005
Renal amino acid, fat and glucose metabolism in type 1 diabetic and non-diabetic humans: effects of acute insulin withdrawal.
    Diabetologia, 2006, Volume: 49, Issue:8

    Topics: Amino Acids; Blood Flow Velocity; Diabetes Mellitus, Type 1; Glucose; Humans; Hypoglycemic Agents; Insulin; Kidney; Leucine; Palmitic Acid; Phenylalanine; Reference Values; Renal Circulation; Substance Withdrawal Syndrome; Tyrosine

2006
Macrophage migration inhibitory factor (MIF) is necessary for progression of autoimmune diabetes mellitus.
    Journal of cellular physiology, 2008, Volume: 215, Issue:3

    Topics: Adoptive Transfer; Animals; Antibodies, Monoclonal; Cell Adhesion; Cell Proliferation; Cells, Cultured; Cyclophosphamide; Cytokines; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Disease Progression; Female; Gene Expression Regulation; Intramolecular Oxidoreductases; Islets of Langerhans; Leukocytes, Mononuclear; Macrophage Migration-Inhibitory Factors; Mice; Mice, Inbred NOD; Nitric Oxide; Nitric Oxide Synthase Type II; RNA, Messenger; Spleen; Streptozocin; Tyrosine

2008
Regulation of phosphatidylinositol 3-kinase activity in liver and muscle of animal models of insulin-resistant and insulin-deficient diabetes mellitus.
    The Journal of clinical investigation, 1993, Volume: 92, Issue:4

    Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Insulin Receptor Substrate Proteins; Insulin Resistance; Liver; Macromolecular Substances; Mice; Mice, Obese; Muscles; Phosphates; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Phosphotransferases (Alcohol Group Acceptor); Phosphotyrosine; Rats; Tyrosine

1993
Protein dynamics in whole body and in splanchnic and leg tissues in type I diabetic patients.
    The Journal of clinical investigation, 1995, Volume: 95, Issue:6

    Topics: Adult; Carbohydrate Metabolism; Diabetes Mellitus, Type 1; Hormones; Humans; Insulin; Leg; Leucine; Male; Muscle Proteins; Phenylalanine; Proteins; Regional Blood Flow; Splanchnic Circulation; Tyrosine

1995
Solid versus liquid phase assays in detection of insulin antibodies. Influence of iodination site on labelled insulin binding.
    Journal of immunological methods, 1994, Mar-10, Volume: 169, Issue:2

    Topics: Adolescent; Adult; Aged; Autoantibodies; Binding Sites, Antibody; Child; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Enzyme-Linked Immunosorbent Assay; Female; Humans; Insulin; Insulin Antibodies; Iodine Radioisotopes; Male; Middle Aged; Radioligand Assay; Tyrosine

1994
Thymic T cell anergy in autoimmune nonobese diabetic mice is mediated by deficient T cell receptor regulation of the pathway of p21ras activation.
    The Journal of experimental medicine, 1993, Apr-01, Volume: 177, Issue:4

    Topics: Animals; Autoimmune Diseases; Diabetes Mellitus, Type 1; Female; Male; Mice; Mice, Inbred BALB C; Mice, Inbred NOD; Phosphorylation; Proto-Oncogene Proteins p21(ras); Receptors, Antigen, T-Cell; T-Lymphocytes; Tetradecanoylphorbol Acetate; Thymus Gland; Tyrosine

1993
Development of autoimmune diabetes in NOD mice is associated with the formation of peroxynitrite in pancreatic islet beta-cells.
    Diabetes, 1997, Volume: 46, Issue:5

    Topics: Animals; Cell Count; Diabetes Mellitus, Type 1; Female; Islets of Langerhans; Leukocytes; Macrophages; Mice; Mice, Inbred BALB C; Mice, Inbred NOD; Nitrates; Tyrosine

1997
Impaired plasma membrane targeting of Grb2-murine son of sevenless (mSOS) complex and differential activation of the Fyn-T cell receptor (TCR)-zeta-Cbl pathway mediate T cell hyporesponsiveness in autoimmune nonobese diabetic mice.
    The Journal of experimental medicine, 1997, Sep-15, Volume: 186, Issue:6

    Topics: Adaptor Proteins, Signal Transducing; Animals; Autoimmune Diseases; Cell Membrane; Cytoskeleton; Diabetes Mellitus, Type 1; Female; GRB2 Adaptor Protein; Guanine Nucleotide Exchange Factors; Membrane Proteins; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred NOD; Phosphorylation; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-cbl; Proto-Oncogene Proteins c-fyn; ras Guanine Nucleotide Exchange Factors; ras Proteins; Receptors, Antigen, T-Cell; Self Tolerance; Signal Transduction; T-Lymphocytes; Tyrosine; Ubiquitin-Protein Ligases

1997
Glycoxidation, and protein and DNA oxidation in patients with diabetes mellitus.
    Clinical science (London, England : 1979), 1998, Volume: 95, Issue:3

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Aged; Arginine; Biomarkers; Case-Control Studies; Chromatography, High Pressure Liquid; Deoxyguanosine; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Humans; Lysine; Middle Aged; Oxidative Stress; Statistics, Nonparametric; Tyrosine

1998
Increased nitrotyrosine in the diabetic placenta: evidence for oxidative stress.
    Diabetes care, 1998, Volume: 21, Issue:10

    Topics: Biomarkers; Chorionic Villi; Diabetes Mellitus, Type 1; Female; Glycated Hemoglobin; Humans; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxidative Stress; Placenta; Pregnancy; Pregnancy in Diabetics; Pregnancy Outcome; Reference Values; Superoxide Dismutase; Tyrosine

1998
Aromatic hydroxylation in animal models of diabetes mellitus.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 1998, Volume: 12, Issue:14

    Topics: Animals; Arginine; Blood Glucose; Diabetes Mellitus, Type 1; Disease Models, Animal; Female; Fructosamine; Hydroxylation; Kidney; Lysine; Malondialdehyde; Mice; Rats; Rats, Inbred BB; Rats, Sprague-Dawley; Streptozocin; Tyrosine

1998
Patients with type 2 diabetes have a high frequency of the C282Y mutation of the hemochromatosis gene.
    Clinical and investigative medicine. Medecine clinique et experimentale, 1998, Volume: 21, Issue:6

    Topics: Adolescent; Adult; Cysteine; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Hemochromatosis; Humans; Male; Middle Aged; Point Mutation; Tyrosine

1998
Whole body protein kinetics using Phe and Tyr tracers: an evaluation of the accuracy of approximated flux values.
    The American journal of physiology, 1999, Volume: 276, Issue:6

    Topics: Adult; Diabetes Mellitus, Type 1; Female; Humans; Insulin; Kinetics; Male; Models, Biological; Phenylalanine; Reference Values; Tyrosine

1999
Tyrosine phosphorylation in type-1 diabetes by immunogold detection: an in vitro human aortic endothelial cell (HAEC) study in the presence of diabetic low density lipoproteins (LDL).
    European journal of histochemistry : EJH, 1999, Volume: 43, Issue:3

    Topics: Cell Line; Cytoplasm; Diabetes Mellitus, Type 1; Endothelium, Vascular; Humans; Immunohistochemistry; Lipid Peroxides; Lipoproteins, LDL; Nuclear Proteins; Phosphorylation; Tyrosine

1999
Role of peroxynitrite in altered fetal-placental vascular reactivity in diabetes or preeclampsia.
    American journal of physiology. Heart and circulatory physiology, 2000, Volume: 278, Issue:4

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adult; Angiotensin II; Antihypertensive Agents; Diabetes Mellitus, Type 1; Epoprostenol; Female; Fetus; Humans; In Vitro Techniques; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide; Nitroglycerin; Oxidative Stress; Placenta; Pre-Eclampsia; Pregnancy; Reactive Oxygen Species; Tyrosine; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents

2000
Oxidative protein damage in type I diabetic patients with and without complications.
    Endocrine research, 2000, Volume: 26, Issue:3

    Topics: Adult; Blood Proteins; Ceruloplasmin; Diabetes Mellitus, Type 1; Erythrocytes; Female; Fructosamine; Glutathione; Glycated Hemoglobin; Humans; Iron; Lipid Peroxides; Male; Oxidative Stress; Protein Binding; Sulfhydryl Compounds; Transferrin; Tyrosine

2000
Oxidative protein damage in early stage Type 1 diabetic patients.
    Diabetes research and clinical practice, 2000, Volume: 50, Issue:3

    Topics: Adolescent; Adult; Antioxidants; Blood Pressure; Blood Proteins; Ceruloplasmin; Child; Diabetes Mellitus, Type 1; Erythrocytes; Female; Glutathione; Glycated Hemoglobin; Humans; Lipid Peroxides; Lipids; Male; Oxidative Stress; Reference Values; Sulfhydryl Compounds; Superoxide Dismutase; Transferrin; Tyrosine

2000
Nitrotyrosine immunostaining correlates with increased extracellular matrix: evidence of postplacental hypoxia.
    Placenta, 2001, Volume: 22 Suppl A

    Topics: Adult; Diabetes Mellitus, Type 1; Embolism, Amniotic Fluid; Extracellular Matrix; Female; Fetal Death; Gestational Age; Humans; Hypoxia; Infant, Newborn; Placenta; Placental Circulation; Pre-Eclampsia; Pregnancy; Retrospective Studies; Tyrosine

2001
Nitric oxide synthesis and oxidative stress in the renal cortex of rats with diabetes mellitus.
    Journal of the American Society of Nephrology : JASN, 2001, Volume: 12, Issue:8

    Topics: Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Kidney Cortex; Male; NADPH Dehydrogenase; Nitric Oxide; Nitric Oxide Synthase; Oxidative Stress; Rats; Rats, Sprague-Dawley; Staining and Labeling; Superoxide Dismutase; Superoxides; Tissue Distribution; Tyrosine

2001
Increase in oxidative stress in kidneys of diabetic Akita mice.
    Bioscience, biotechnology, and biochemistry, 2002, Volume: 66, Issue:4

    Topics: Animals; Diabetes Mellitus, Type 1; Disease Models, Animal; Kidney; Lysine; Mice; Mice, Mutant Strains; Oxidation-Reduction; Oxidative Stress; Tyrosine

2002
Aberrant production of IL-12 by macrophages from several autoimmune-prone mouse strains is characterized by intrinsic and unique patterns of NF-kappa B expression and binding to the IL-12 p40 promoter.
    Journal of immunology (Baltimore, Md. : 1950), 2002, Jul-01, Volume: 169, Issue:1

    Topics: Animals; Autoimmune Diseases; Cell Extracts; Cell Nucleus; Diabetes Mellitus, Type 1; Dimerization; DNA-Binding Proteins; Genetic Predisposition to Disease; Interleukin-12; Interleukin-12 Subunit p40; Lupus Nephritis; Macrophages, Peritoneal; Male; Mice; Mice, Inbred MRL lpr; Mice, Inbred NOD; Mice, Inbred NZB; NF-kappa B; Phosphorylation; Promoter Regions, Genetic; Protein Binding; Protein Subunits; Proto-Oncogene Proteins c-rel; RNA, Messenger; Tyrosine

2002
The child with an unusual odor. A clinical resumé.
    Clinical pediatrics, 1976, Volume: 15, Issue:1

    Topics: Amino Acid Metabolism, Inborn Errors; Child; Child, Preschool; Choline; Diabetes Mellitus, Type 1; Diabetic Ketoacidosis; Humans; Infant; Leucine; Maple Syrup Urine Disease; Metabolism, Inborn Errors; Methionine; Odorants; Phenylketonurias; Tyrosine

1976
Effect of iodination site on binding of radiolabeled ligand by insulin antibodies and insulin autoantibodies.
    Clinical chemistry, 1988, Volume: 34, Issue:2

    Topics: Adult; Aged; Antibodies; Autoantibodies; Autoimmune Diseases; Binding Sites; Binding Sites, Antibody; Diabetes Mellitus, Type 1; Epitopes; Female; Humans; Immune Sera; Insulin; Iodine; Iodine Radioisotopes; Male; Middle Aged; Tyrosine

1988
[Reference levels for phenylalanine and tyrosine in discs impregnated with blood during analysis by HPLC].
    Anales espanoles de pediatria, 1988, Volume: 28, Issue:5

    Topics: Adolescent; Adult; Child; Child Nutrition Disorders; Child, Preschool; Chromatography, High Pressure Liquid; Diabetes Mellitus, Type 1; Humans; Infant; Infant Nutrition Disorders; Infant, Newborn; Phenylalanine; Reference Values; Tyrosine

1988
Hormonal influences on the concentration of tyrosine in blood.
    Clinica chimica acta; international journal of clinical chemistry, 1972, Volume: 42, Issue:1

    Topics: Acromegaly; Adolescent; Androgens; Contraceptives, Oral; Diabetes Mellitus, Type 1; Epinephrine; Fasting; Female; Glucagon; Glucose; Glucose Tolerance Test; Hormones; Humans; Hyperthyroidism; Hypoglycemia; Hypothyroidism; Insulin; Male; Pregnancy; Sex Factors; Tyrosine

1972