tyrosine has been researched along with Diabetes Mellitus, Adult-Onset in 162 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (1.85) | 18.7374 |
| 1990's | 13 (8.02) | 18.2507 |
| 2000's | 64 (39.51) | 29.6817 |
| 2010's | 65 (40.12) | 24.3611 |
| 2020's | 17 (10.49) | 2.80 |
| Authors | Studies |
|---|---|
| Azul, L; Figueirinha, A; Leandro, A; Queiroz, M; Seiça, R; Sena, CM | 1 |
| Kim, JH; Kim, KY; Kim, MS; Lee, SY; Lee, YA; Lee, YJ; Shin, CH | 1 |
| Chepurny, OG; Collier, JJ; Cooney, RN; Holz, GG; Leech, CA; Meng, Q; Molnar, ME; Pruekprasert, N | 1 |
| Calderón-Torres, CM; Murguía-Romero, M; Ortiz-Reyes, AE | 1 |
| Andersson, O; Charbord, J; Chu, L; Dirice, E; Kulkarni, RN; Liu, KC; Mattsson, CL; Miskelly, MG; Teinturier, R; Terasaki, M; Wierup, N; Zhou, Q | 1 |
| Auladell, C; Bulló, M; Camins, A; Cano, A; Carrasco, M; Ettcheto, M; Folch, J; Fortuna, A; Olloquequi, J; Sanchez-López, E; Verdaguer, E | 1 |
| Anghel, R; Forsea, L; Gales, L; Georgescu, M; Mitrea, D; Mitrica, R; Serbanescu, L; Stanculescu, I; Stefanica, I; Trifanescu, O | 1 |
| Chu, N; Jie, H; Leung, K; Ling, J; Poon, E | 1 |
| Chaimontri, C; Iamsaard, S; Sawatpanich, T; Wu, AT; Yannasithinon, S | 1 |
| Araki, E; Cai, W; Fukuda, K; Fukuda, T; Igata, M; Kahn, CR; Kondo, T; Okagawa, S; Okubo, Y; Otsuka, Y; Sakaguchi, M; Sakaguchi, N; Sato, Y; Tseng, YH; Yamagata, K; Yoshizawa, T | 1 |
| Chen, C; Jiang, P; Jiao, L; Li, B; Li, H; Li, J; Liu, F; Ren, T; Wang, D; Wu, W | 1 |
| Iamsaard, S; Yannasithinon, S | 1 |
| Artamonova, A; Hayes, KC; Koledova, VV; Rha, C; Sambanthamurthi, R; Schneider, K; Sinskey, AJ; Subramaniam, A; Weinberg, RP | 1 |
| Delcheva, GT; Maneva, AI; Stankova, TR; Vladeva, SV | 1 |
| Aasen, T; Abdul Moin, NI; Abdul Wafi, S; Aboukameel, A; Abu-Bakar, N; Acharya, A; Ackermans, L; Adaramoye, O; Adarsh, KV; Adeosun, WA; Ahmad, NH; Ahmadi, F; Akanni, O; Akbar, M; Akbulak, RO; Akev, N; Akkaya, Ö; Al-Rashed, S; AlAbbad, S; Alabi, O; Alappat, BJ; Alcalá, S; Alcoutlabi, M; Aleppo, G; Alexander Ross, JB; Alexander, JH; Alexander, R; Alias, A; Alimba, C; Alken, FA; Allan, R; Alpers, M; Alsbou, EM; Amarasiri, SS; An, T; Anastasiadis, F; Anastassiadou, M; Anderson, KC; Andronikos, P; Anheyer, D; Annapurna, K; Anorlu, RI; Anten, MM; Anthopoulos, TD; Araujo-Castillo, RV; Aravamudhan, S; Arawwawala, LDAM; Arulsamy, N; Arunamata, A; Asghar, A; Asiri, AM; Aslanidou, T; Astrakhantseva, IV; Astutik, E; Attanayake, AP; Atwater, BD; Audureau, E; Augusto, S; Bakare, A; Banach, M; Bandelier, P; Banerjee, S; Barral, M; Bascuñán, J; Bates, FS; Bauer, NJC; Bayrak, BB; Beck, RW; Beckervordersantforth, J; Beeri, R; Begum, R; Beldi-Ferchiou, A; Bellingham, G; Ben-Tal, N; Bendib, I; Bergenstal, RM; Berger, MF; Bernasconi, G; Berry, S; Beuvon, F; Bi, WJ; Bi, Z; Bianconi, V; Bibi, I; Blank, BR; Bliemeister, E; Bobkowski, W; Bode, AM; Booth, CM; Bose, U; Boyd, K; Brancato, A; Brenmoehl, J; Brogi, E; Bronzo, P; Brooks, T; Brown, D; Brown, DN; Bruce, D; Buan, MEM; Bueno-Hernández, F; Bugielski, B; Bulavaitė, A; Buscagan, TM; Buxton, R; Caffaro, MM; Cai, Q; Cai, X; Cai, Y; Calhoun, P; Callander, N; Cambier, S; Camparo, P; Canales-Vargas, EJ; Canham, K; Cantu, J; Cao, J; Cao, JW; Cao, P; Cao, T; Cao, X; Caravella, BA; Carcadea, E; Carè, J; Carmichael, P; Carrasco Cabrera, L; Carteaux, G; Carvalho, PDS; Casarez, E; Cazorla, M; Celestrin, CP; Chakraborty, NK; Chan, B; Chandarlapaty, S; Chandgude, AL; Chang, CC; Chang, JH; Chang, X; Chang, Y; Chankhanittha, T; Chantanis, S; Chapovetsky, A; Chavan, S; Chen, B; Chen, D; Chen, F; Chen, G; Chen, H; Chen, J; Chen, K; Chen, KJ; Chen, KP; Chen, L; Chen, MA; Chen, Q; Chen, S; Chen, W; Chen, WF; Chen, X; Chen, Y; Cheng, D; Cheng, J; Cheng, Q; Cheon, GJ; Chiu, SC; Cho, CH; Cho, J; Choi, H; Choi, JS; Choi, YH; Christie, P; Chu, CH; Chu, Y; Chung, DH; Chung, F; Cline, JP; Cohen, A; Cohen, AD; Cohen, NJ; Comen, E; Compter, I; Cong, J; Cong, Z; Cooper, A; Cornud, F; Costa, C; Costa, S; Covey, A; Cowan, AM; Cramer, H; Cruz-Rivera, C; Cui, J; Cui, M; Cui, Y; Cui, YH; Culquichicón, C; Cushman, T; D'Auria, SJ; da Silva, J; Dalgediene, I; Danenberg, HD; Das, S; Dasgupta, K; Daubit, IM; de Oliveira, PD; de Prost, N; De Ruysscher, D; Dearman, K; Decato, D; Delfau-Larue, MH; Deng, L; Dhakate, SR; Dharuman, V; Di Costanzo, N; Dickler, MN; Dinehart, EE; Ding, D; Dinh, TK; Divya, KP; Djifack Tadongfack, T; Do, T; Domínguez-Roldan, R; Domínguez-Zambrano, E; Dömling, A; Donato, MD; Dong, JH; Dong, W; Dong, X; Dong, XR; Dong, Y; Dong, Z; Downs, M; Drutskaya, MS; Du, B; Du, F; Du, H; Du, L; Du, X; Duan, Z; Duangthip, D; Dunstand-Guzmán, E; Duong, F; Eckert, DJ; Edelhäuser, BAH; Eekers, DBP; Efendi, F; Efraimidis, P; Ehrenberg, H; Ehsanbakhsh, Z; Eickholt, C; Eksterowicz, J; El Mobadder, M; El-Araby, IE; El-Magd, MA; El-Tarabany, MS; Elgorban, AM; Engelmann, D; English, KL; Esfandiari, H; Eslami, B; Espinosa-Cuevas, A; Eswara, S; Faber, E; Fan, XH; Fan, Y; Fang, J; Fang, Z; Fantin, VR; Fei, P; Feng, G; Feng, H; Feng, J; Feng, X; Feng, XJ; Fennell, TR; Fernández-Moreira, V; Ferraz, ABF; Ferreras, KN; Flores, K; Flores-Pérez, I; Flox, C; Fluharty, FL; Fokouong Tchoffo, E; Folefack, GO; Foroutan, T; Fort, D; Fourati, S; Fousas, S; Frapard, T; Freguia, S; Friedman, DJ; Friedman, LS; Fu, D; Fu, Q; Fu, Y; Fujinami, S; Furihata, K; Gal, RL; Gan, H; Gao, C; Gao, F; Gao, R; Gao, SS; Gao, W; Gao, XC; Gao, Y; Gao, Z; Garozi, L; Ge, J; Georgiopoulos, A; Gerakiou, K; Ghazimirsaeed, SM; Ghazimirsaeed, ST; Gimeno, MC; Gjestad, R; Glurich, I; Goetchius, E; Goland, S; Goldstein, S; Gonçalves, CM; Gonçalves, H; Gong, Q; Gonzalez, D; Goplen, FK; Gorshkova, EN; Gotsman, I; Govindasamy, V; Granger, CB; Greco, L; Grigoriadou-Skouta, E; Grigoropoulos, P; Grivicich, I; Gromov, NV; Gruber, S; Grytczuk, M; Grzech-Leśniak, K; Gu, L; Gu, S; Gu, Z; Guadagnini, D; Guan, H; Guilliams, M; Guo, J; Guo, L; Gupta, A; Gupta, SK; Gurzu, S; Gutleb, AC; Haban, A; Hablitz, JJ; Hadisuyatmana, S; Hahn, S; Haiges, R; Hallal-Calleros, C; Hamed, M; Hammad, N; Hammer, N; Han, C; Hao, Y; Harnett, J; Has, EMM; Hassanpour, K; Hatzopoulos, D; Hawaldar, R; He, X; He, Y; He, YY; He, Z; Heberman, D; Heckl, D; Hegde, H; Henson, MA; Hernández-Velázquez, VM; Herrera, E; Hijazi, Z; Hirayama, K; Hirth, JM; Hoeben, A; Hohnloser, SH; Hong, M; Hood, K; Hoplock, LB; Hopman, WM; Horlbogen, LM; Hossein Rashidi, B; Hou, G; Hou, H; Hou, J; Hou, Y; Hu, J; Hu, W; Hu, X; Hua, W; Huang, G; Huang, H; Huang, J; Huang, T; Huang, W; Huang, Y; Huang, YD; Huang, Z; Hudis, CA; Hue, S; Huo, J; Hussain, M; Hvas, AM; Ichii, T; Ide Zeuna, J; Ilyas, S; Inoue, T; Iranzo, A; Irfan, M; Iwasa, Y; Iwashita, Y; Izgorodina, EI; J R, A; Jaber, WA; Jaborek, JR; Jacobus, SJ; Jadeja, SD; Jafarabadi, M; Jalan, D; Jamil, MI; Jarrah, S; Jarvis, D; Jayatilaka, KAPW; Jemal-Turki, A; Jeon, YK; Jeong, N; Jeong, SH; Jeong, SY; Jermy, M; Jhaveri, K; Ji, H; Ji, K; Ji, RY; Jiang, F; Jiang, J; Jiang, X; Jiang, Y; Jiao, Q; Jilani, K; Jiménez-Guerrero, P; Jin, L; Jo, YH; Johnson, JG; Johnson, ML; Jones, WS; Jose, S; Jularic, M; Jung, I; Jung, YJ; Jungen, C; Junttila, MR; Kache, S; Kahanovitch, U; Kalantzi, KI; Kallio, T; Kamnoedboon, P; Kang, CH; Kang, H; Kang, J; Kang, KW; Kapoor, P; Karmakar, D; Kartalis, A; Kauranen, P; Kazocina, A; Keikha, F; Keltai, M; Kershaw, SV; Kettani, M; Khalvati, S; Khandhar, S; Khosla, N; Kiely, CJ; Kim, CC; Kim, H; Kim, MJ; Kim, Y; Kim, YH; Kim, YT; Kimoto, E; Kiyu, A; Klatt, N; Kobayashi, M; Koh, J; Köhler, R; Kondadasula, SV; Kong, H; Kong, W; Kong, X; Kotidis, A; Kotwal, A; Kouvari, M; Kozhinov, AN; Kruger, D; Kuang, S; Kuang, Y; Kubota, M; Kuklik, P; Kumar, P; Kumar, SK; Kuo, YF; Kurup, SP; Kusuhara, H; Kuswanto, H; Lacouture, ME; Lambin, P; Lang, CC; Langroudi, FH; Lanman, RB; Larsen, OH; Laskin, J; Le, VH; Leach, M; Lee, BG; Lee, DF; Lee, DS; Lee, HJ; Lee, SB; Lee, YA; Lei, Y; Lekashvili, O; Lelj, F; Lemin, AS; Lemoine, J; Leuschner, R; Li, B; Li, BT; Li, C; Li, D; Li, F; Li, G; Li, H; Li, HW; Li, J; Li, M; Li, P; Li, Q; Li, S; Li, W; Li, X; Li, XY; Li, Y; Li, Z; Lian, Y; Liang, C; Liao, J; Liao, W; Liao, Y; Lin, D; Lin, W; Lin, YL; Lindbäck, J; Lindsay, AP; Ling, J; Linser, PJ; Liu, C; Liu, H; Liu, JJ; Liu, L; Liu, Q; Liu, SF; Liu, X; Liu, Y; Liu, Z; Liu, ZM; Lo Sterzo, C; Lo, ECM; Lobchuk, MM; Lodge, TP; Logotheti, S; Lonial, S; Lopes, G; Lopes, RD; Lopez, J; Lopez, SA; López-Santos, AL; López-Sendón, JL; Loring, Z; Louis, C; Lovita, AND; Lu, DZ; Lu, H; Lu, J; Lu, K; Lu, TT; Lu, Y; Luengo, A; Lum, LG; Luna, JM; Luo, L; Luo, R; Luo, T; Luo, X; Luo, Z; Lv, B; Lymperopoulos, N; Lyras, A; Lyu, Y; M Kannan, A; Ma, H; Ma, M; Ma, Q; Ma, S; Ma, WY; Ma, Y; Maalouf, E; Machado, FA; Maeda, K; Magrans, JO; Maharani, A; Maia, G; Mainwaring, RD; Maji, TK; Majumdar, K; Mannarino, MR; Mansuri, MS; Marinescu, SC; Markatos, G; Marquardt, S; Marraiki, N; Martens, C; Martínez, TJ; Marumo, K; Maruyama, H; Marwani, HM; Marzo, I; Masrati, G; Matamba, P; Mathialagan, S; Matys, J; Mayatra, JM; Mboua, PC; McArthur, T; McCrimmon, RJ; McIntosh, S; McSpadden, S; Medina-Campos, ON; Medvedovsky, AT; Mei, Z; Mekontso-Dessap, A; Menezes, AMB; Meng, J; Meng, P; Meng, Y; Menter, A; Mets, MB; Mets-Halgrimson, R; Metzger, T; Metzler-Nolte, N; Meyer, C; Mi, Y; Michailoviene, V; Mikrogeorgiou, A; Militz, H; Miller Iii, TF; Minarowska, A; Mir, S; Miron, I; Miyake, T; Moayer, F; Modi, S; Moeller, SJ; Mohamad, MN; Mohammed, EHM; Mokhonov, VV; Mondal, A; Moore, J; Moravcova, M; Mordi, IR; Mordi, NA; Mortensen, NP; Moscariello, C; Moser, J; Moynahan, ME; Mu, J; Mu, W; Mudduwa, LKB; Mukherjee, S; Mukhtar, A; Mulkey, DK; Murr, N; Mushtaq, Z; Muthuswamy, N; Mutlu, O; Muto, C; Myroforou, I; Na, KJ; Nabi, M; Nagornov, KO; Nagy, RJ; Naik, A; Nakajima, K; Nam, KT; Nam, YW; Namburath, M; Nammour, S; Namour, A; Namour, M; Nanan, S; Natsume, H; Nave, S; Naveed, A; Nazir, H; Ndubaku, C; Nedospasov, SA; Neradilek, MB; Newcomb, C; Nguépy Keubo, FR; Nguyen, M; Ning, J; Ning, Q; Noguchi, S; Nordahl, SHG; Nordfalk, KF; Norton, L; Noupoue, EM; Nouri, SS; Nowak, JK; Núñez, K; Oakes, K; Odegaard, JI; Ogorodnikova, OL; Ogunsuyi, O; Oh, HK; Oh, HR; Oh, KH; Ohgi, K; Okunade, KS; Oliveira, AG; Olorunfemi, G; Olsen, ML; Olson, BA; Omari, KW; Ondruschka, B; Orfali, R; Orkopoulos, A; Orlowski, RZ; Oser, SM; Oser, TK; Özcan, M; Padilla, V; Paeng, JC; Pajuelo-Lozano, N; Pal, SK; Palmieri, S; Palomeque, E; Pan, W; Panagiotakos, DB; Pandey, M; Pang, D; Pang, Q; Pangarah, CA; Panny, A; Paparella, A; Papirio, S; Papouskova, K; Parang, K; Park, HJ; Park, IK; Park, S; Parker, TL; Parkhomenko, A; Parmon, VN; Parsons, B; Parsons, J; Patel, PR; Patil, S; Patsourakos, NG; Patterson, KC; Pavlidis, P; Pedernera, M; Pedersen, R; Pedraza-Chaverri, J; Pellegrini, M; Peña-Chora, G; Pereira, EDM; Pereira, MADS; Peretz, A; Perez-Padilla, R; Perlman, GY; Perona, R; Petras, C; Phuntsho, S; Picada, JN; Pinder, TA; Piper, LFJ; Pirozzi, F; Pirro, M; Pleckaityte, M; Ploutz-Snyder, LL; Ploutz-Snyder, R; Pogorzelski, A; Poles, L; Postma, AA; Prager, A; Prakash, J; Punn, R; Pützer, BM; Qi, J; Qi, MC; Qi, Y; Qian, J; Qian, Y; Qiang, L; Qiu, J; Qu, Y; Rabiu, KA; Rahighi, S; Rahman, MM; Rahmani, B; Rajkumar, SV; Ramanathan, R; Raras, TYM; Rashi, Y; Rasool, G; Rathore, MG; Ratnawati, R; Ratola, N; Raucci, U; Ray, SK; Razavi, P; Razazi, K; Razek, S; Razi, SS; Reback, M; Reddy, K; Rees, DC; Reginatto, FH; Reich, H; Reis-Filho, JS; Ren, X; Ren, Y; Renner, G; Rey, G; Reymen, B; Riaz, M; Ricci, A; Richardson, PG; Richter, C; Riga, M; Ritchie, C; Rivoal, S; Roberts, W; Robson, ME; Rocha, GZ; Rodrigues, AD; Rogach, AL; Rojas, A; Rosenberg, A; Rosenberg, E; Rosenheck, RA; Roslan, K; Rothenberger, C; Rouschop, KMA; Rubagumya, F; Ryan, CM; Ryder, JW; Saad, MJA; Sacan, O; Sacchi, A; Sahebkar, A; Saini, A; Sainz, B; Sajo, EA; Sakizadeh, J; Saleh, AA; Salgado Júnior, IB; Salvi, R; Samoylova, YV; Samuni, A; Sanchez, DM; Sanchez-Perez, I; Santos, M; Sarapulova, A; Sardot, T; Saud, N; Sauerbier, P; Scaltriti, M; Schaeffer, B; Schalk, DL; Scherschel, K; Schijven, MP; Schreuder, HWR; Schuhmacher, M; Schultz-Lebahn, A; Schwarzl, J; Scott, JM; Sebayang, SK; Seeger, ZL; Segabinazi Peserico, C; Selenica, P; Serio, A; Seruga, B; Shah, A; Shah, C; Shah, PD; Shahrokh Tehraninezhad, E; Shan, A; Shao, Z; Sharma, AMR; Sharma, RK; Shen, J; Shen, R; Shi, X; Shi, Y; Shi, ZE; Shih, YC; Shimohata, H; Shimpi, N; Shin, SH; Shon, HK; Shuvy, M; Siddique, AB; Siegbahn, A; Sikandar, M; Silvani, Y; Singh, A; Singh, AK; Singh, D; Singh, JS; Singh, KP; Singh, M; Situ, B; Skipper, MT; Skouloudi, M; Sloane, BF; Smyrnioudis, N; Snyder, MA; Söhnchen, C; Solis Condor, R; Solit, DB; Someya, S; Song, H; Song, J; Song, W; Song, Y; Sorokina, KN; Soshi, S; Soyer, P; Spitschak, A; Sreekrishnan, TR; Srinivasan, M; Staruschenko, A; Steel, A; Stefan-van Staden, RI; Stein, AM; Strayer, H; Struthers, AD; Su, H; Su, Q; Su, X; Sudore, RL; Sugimura, H; Sugiyama, Y; Sujuti, H; Sumner, SJ; Sun, B; Sun, D; Sun, H; Sun, J; Sun, JY; Sun, X; Sun, Y; Sun, Z; Sung, YC; Surenaud, M; Sutimantanapi, D; Suwandaratne, NS; Swaroop, S; Sychrova, H; Syed, A; Szczepanik, M; Szederjesi, J; Szodorai, R; Tacy, TA; Tadelle, RM; Takayasu, M; Tammeveski, K; Tan, H; Tan, M; Tang, HX; Tang, S; Tang, X; Tanokura, M; Tao, F; Tao, H; Tarafdari, A; Tarín-Carrasco, P; Tasson Tatang, C; Teixeira, JP; Thakur, A; Theobald, A; Thevenot, P; Thomaidis, K; Tian, J; Tillib, SV; Toma, C; Tomita, M; Tonchev, I; Tong, F; Toy, W; Trypuć, M; Tselepis, AD; Tsetseris, L; Tsikouri, GE; Tsikouris, EI; Tsoplifack, CB; Tsoumani, ME; Tsujimoto, R; Tsybin, YO; Tu, J; Tu, TM; Turco, M; Turkyilmaz, IB; Uddin, MJ; Ung, J; Unsihuay, D; Utsunomiya, T; Vagenende, B; Vaishnav, J; Valdes, C; Validad, MH; Valle, J; van Ginkel, MPH; van Grevenstein, WMU; Vanderpuye, V; Vasan, N; Vasilenko, EA; Vasques, GJ; Vavoulis, P; Verani, A; Veziroglu, E; Viegas, A; Vitali, MG; Vitsas, G; Voccio, JP; Vogiatzidis, C; Volow, A; Volpin, F; Vourvahis, M; Wagner, LI; Walkowiak, J; Wallace, R; Wallentin, L; Wan, D; Wan, L; Wan, T; Wang, C; Wang, F; Wang, FN; Wang, H; Wang, J; Wang, L; Wang, Q; Wang, S; Wang, T; Wang, W; Wang, X; Wang, XW; Wang, Y; Wang, YS; Wang, Z; Ward, J; Ward, L; Waseem, R; Watson, DF; Weber, P; Wehrmeister, FC; Wei, CH; Wei, H; Wei, L; Wei, Q; Wei, Y; Weinstock, RS; Weiss, M; Welborn, M; Wen, L; Wen, LM; Wen, Q; Wen, Z; Wesseling, P; Westerbergh, J; White, K; Wick, MP; Willems, S; Wiyasa, IWA; Wójciak, R; Wolkenhauer, O; Won, HH; Wong, J; Woo, YC; Wood, LS; Wu, CT; Wu, CY; Wu, D; Wu, G; Wu, J; Wu, K; Wu, M; Wu, Q; Wu, T; Wu, W; Wu, X; Wu, XT; Wu, Y; Xi, D; Xi, J; Xiang, W; Xiang, Y; Xiao, M; Xiao, Z; Xie, H; Xie, Q; Xie, S; Xie, X; Xing, M; Xing, YL; Xu, C; Xu, X; Xu, Y; Xu, Z; Xue, F; Xue, XD; Yaglioglu, HG; Yamada, H; Yamashita, M; Yan, W; Yan, Z; Yanardag, R; Yang, D; Yang, H; Yang, K; Yang, QQ; Yang, R; Yang, S; Yang, T; Yang, X; Yang, Y; Yao, H; Yao, Y; Yari, D; Yassin, MT; Ye, C; Ye, J; Ye, Q; Yildiz, EA; Ying, S; Yoon, H; Yu, D; Yu, K; Yu, N; Yu, PL; Yuan, C; Yuan, D; Yuan, LJ; Yuan, Z; Yuen, N; Zagatto, AM; Zakaria, Y; Zalewski, AM; Zamora, S; Zavorotinskaya, T; Zeid, JL; Zeinoun, T; Zeng, C; Zerby, HN; Zhan, X; Zhang, A; Zhang, D; Zhang, E; Zhang, F; Zhang, H; Zhang, J; Zhang, L; Zhang, M; Zhang, P; Zhang, Q; Zhang, QY; Zhang, RG; Zhang, S; Zhang, T; Zhang, X; Zhang, Y; Zhang, YY; Zhao, CK; Zhao, H; Zhao, J; Zhao, K; Zhao, Q; Zhao, S; Zhao, T; Zhao, XQ; Zhao, Y; Zhao, Z; Zheng, J; Zheng, L; Zheng, Y; Zhou, B; Zhou, G; Zhou, L; Zhou, T; Zhou, X; Zhu, C; Zhu, J; Zhu, Y; Zhu, ZQ; Zhuang, T; Zimmermannova, O; Zin, NNINM; Zisimos, K; Zoghebi, KA; Zonder, JA; Zou, C; Zwirner, J | 1 |
| Fang, ZZ; Feng, XF; Li, J; Luo, HH; Sun, XY; Yang, X | 1 |
| Arzhanova, O; Chepanov, S; Kapustin, R; Kopteeva, E | 1 |
| Adamski, J; Cuadrat, R; Floegel, A; Hoffmann, P; Jäger, S; Pischon, T; Prehn, C; Schulze, MB; Wittenbecher, C | 1 |
| Nomoto, D; Shigemori, H; Tsunoda, T | 1 |
| Bahnson, J; Bihlmeyer, N; Chen, H; Ilkayeva, O; Kwee, LC; Laferrère, B; Muehlbauer, MJ; Newgard, CB; Purnell, JQ; Shah, SH; Wolfe, B; Xavier Pi-Sunyer, F | 1 |
| Al-Majdoub, M; Ali, A; Carstensen, B; Ridderstråle, M; Safai, N; Spégel, P; Suvitaival, T; Vestergaard, H | 1 |
| Cao, YF; Fang, ZZ; Gu, WQ; Han, L; Jiang, CT; Li, J; Li, SN; Song, M; Sun, XY; Yang, X | 1 |
| Dong, T; Fukunaga, K; Ibata, T; Imachi, H; Iwama, H; Kobayashi, T; Lyu, J; Murao, K; Sato, S; Yonezaki, K; Yoshimoto, T; Zhang, G | 1 |
| Bae, SS; Ha, HK; Han, M; Jung, ES; Kim, IY; Kim, SS; Lee, DW; Lee, HW; Lee, MY; Lee, SB; Lovett, DH; Rhee, H; Seong, EY; Song, SH | 1 |
| Guo, Z; Li, J; Man, F; Pan, Q; Wang, H; Wang, W; Xu, J; Yan, W; Zhou, Y | 1 |
| Dong, X; Gräslund, A; Jarvet, J; Sholts, SB; Svantesson, T; Wallin, C; Wärmländer, SKTS | 1 |
| Bae, KH; Han, BS; Kim, JS; Kim, WK; Lee, EW; Lee, SC; Oh, KJ | 1 |
| Deubel, S; Grune, T; Höhn, A; Kehm, R; Rückriemen, J; Weber, D | 1 |
| Kuusisto, J; Laakso, M; Smith, U; Stancáková, A; Vangipurapu, J | 1 |
| Brownell, LA; Corneliusen, B; Jia, Q; Pantier, M; Yimam, M; Zhao, J | 1 |
| Aslan, I; Aslan, M; Tuzcu, H | 1 |
| Coppey, LJ; Dake, BL; Davidson, EP; Holmes, A; Lupachyk, S; Oltman, CL; Peterson, RG; Yorek, MA | 1 |
| Barba, J; Beaumont, J; Coma-Canella, I; Díez, J; González, A; Huerta, A; López, B; Ravassa, S | 1 |
| Barnucz, E; Gwanmesia, PN; Hirschberg, K; Korkmaz, S; Li, S; Loganathan, S; Mátyás, C; Merkely, B; Németh, BT; Oláh, A; Páli, S; Radovits, T; Szabó, G; Zubarevich, A | 1 |
| Barbieri, L; De Luca, G; Marino, P; Schaffer, A; Verdoia, M | 1 |
| Carvalho, AL; Favarato, D; Garcia, RM; Hueb, W; Kalil Filho, R; Maranhão, RC; Ramires, JA; Rezende, PC; Roggério, A; Segre, CA; Sprandel, Mda C; Strunz, CM | 1 |
| Gong, YZ; Liao, DF; Liu, HY; Wang, J; Xie, XJ; Yang, HX; Zou, T | 1 |
| Chmiel, A; Konieczynska, M; Lados-Krupa, A; Undas, A | 1 |
| Bao, Y; Chen, T; Hu, C; Huang, F; Jia, W; Liu, J; Ma, X; Ni, Y; Xie, G; Zhao, A | 1 |
| Chen, B; Hu, X; Li, G; Li, Q; Liu, H; Liu, Y; Qin, L; Qin, S; Zhang, X; Zheng, T | 1 |
| Brlecic, P; Brune, M; Karck, M; Korkmaz-Icöz, S; Lehner, A; Li, S; Radovits, T; Ruppert, M; Sun, X; Szabó, G; Vater, A; Zorn, M | 1 |
| Chen, HJ; Chen, PF; Lai, PY; Yang, YF | 1 |
| Bao, Y; Chen, T; Hu, C; Huang, F; Jia, W; Ma, X; Ni, Y; Rajani, C; Zhao, A; Zheng, X | 1 |
| Ärnlöv, J; Berne, C; Brandmaier, S; Broeckling, CD; Fall, T; Ganna, A; Giedraitis, V; Gieger, C; Ingelsson, E; Lind, L; Magnusson, PK; Meitinger, T; Nowak, C; Pedersen, NL; Peters, A; Prenni, JE; Ripatti, S; Salihovic, S; Strauch, K; Sundström, J; Tukiainen, T; Wang-Sattler, R | 1 |
| Wu, Y; Yang, G; Ye, S | 1 |
| Ahanchi, SS; Hrabie, JA; Jiang, Q; Kapadia, MR; Keefer, LK; Kibbe, MR; Martinez, J; Pearce, CG; Saavedra, JE; Tsihlis, ND; Varu, VN | 1 |
| Abengoechea, S; Ballester, J; Elizalde, J; Fernández-Novell, JM; Guinovart, JJ; Nadal, J; Ramió-Lluch, L; Reverter, JL; Rivera, MM; Rodríguez-Gil, JE | 1 |
| Barillari, G; Bigotto, E; Fabbro, E; Pasca, S | 1 |
| Basic, J; Jevtovic-Stoimenov, T; Kamenov, B; Kocic, GM; Kocic, R; Nikolic, G; Pavlovic, D; Pavlovic, R; Pavlovic, V; Sokolovic, D; Stojanovic, S; Veljkovic, A | 1 |
| Bajirovic, V; Byun, J; Kellogg, A; Oral, E; Pennathur, S; Pop-Busui, R; Raffel, D; Stevens, MJ; Vivekanandan-Giri, A | 1 |
| Abramsson-Zetterberg, L; Asgård, R; Basu, S; Johansson, C; Möller, L; Rytter, E; Sjödin, A; Vessby, B | 1 |
| Abbott, L; Gao, X; Park, Y; Wilson, E; Yang, J; Zhang, C; Zhang, H; Zimmer, W | 1 |
| Liu, Y; Wang, B; Wang, J; Xu, Q | 1 |
| Bouzakri, K; Halban, PA; Ribaux, P | 1 |
| Flacke, F; Forst, S; Forst, T; Hohberg, C; Krasner, A; Pfützner, A; Pichotta, P; Steiner, S; Tarakci, E | 1 |
| Messina, LM; Nowicki, PT; Park, B; Tie, G; Yan, J; Yan, Y | 1 |
| Sim, MK; Sim, SZ; Tsi, D; Wong, YC; Xu, XG | 1 |
| De Cristofaro, R; De Filippis, V; Lancellotti, S; Mannucci, PM; Palla, R; Peyvandi, F; Pitocco, D; Pozzi, N; Rocca, B; Rutella, S | 1 |
| Ceballos-Reyes, GM; Garcia-Sanchez, JR; Hicks, JJ; Medina-Navarro, R; Montes-Cortes, DH; Olivares-Corichi, IM | 1 |
| Hsu, MF; Meng, TC | 1 |
| Choi, HC; He, C; Xie, Z | 1 |
| Baseler, WA; Dabkowski, ER; Frisbee, JC; Hollander, JM; Powell, M; Razunguzwa, TT; Williamson, CL | 1 |
| Arcaro, G; Chiamulera, C; Degan, M; Di Chio, M; Grigoli, L; Guglielmi, V; Klouckova, I; Lechi, A; Lovato, L; Marini, M; Mechref, Y; Meneguzzi, A; Minuz, P; Novotny, MV; Tedesco, V; Tomelleri, G; Tonin, P; Vattemi, G | 1 |
| Choi, KD; Chun, KH; Ciaraldi, TP; Henry, RR; Jung, Y; Kim, YB; Lee, DH | 1 |
| Abe, K; Izuchi, R; Misaka, T; Nakai, Y; Okada, S; Takahashi, H; Ushiama, S | 1 |
| Adaikalakoteswari, A; Parving, HH; Rabbani, N; Rossing, K; Rossing, P; Tarnow, L; Thornalley, PJ | 1 |
| Brasnyó, P; Cseh, J; Halmai, R; Laczy, B; Markó, L; Mérei, A; Mészáros, LG; Mikolás, E; Mohás, M; Molnár, GA; Sümegi, B; Szijártó, IA; Wittmann, I | 1 |
| Corretti, V; Ferrannini, E; Madec, S; Santini, E; Solini, A | 1 |
| Abengoechea, S; Ballester, J; Elizalde, J; Fernández-Novell, JM; Nadal, J; Ramió-Lluch, L; Reverter, JL; Rivera, MM; Rodriguez, JE | 1 |
| Bruno, RM; Daghini, E; Di Paco, I; Ghiadoni, L; Landini, L; Magagna, A; Salvati, A; Santini, E; Solini, A; Taddei, S; Versari, D | 1 |
| Dellsperger, KC; Lee, S; Park, Y; Zhang, C | 1 |
| Fujishima, H; Fujita, H; Komatsu, K; Morii, T; Narita, T; Sakamoto, T; Takahashi, T; Yamada, Y | 1 |
| Benigni, A; Bisighini, C; Cattaneo, S; Corna, D; Fiordaliso, F; Lionetti, V; Pagani, C; Remuzzi, G; Rottoli, D; Salio, M; Zambelli, V; Zoja, C | 1 |
| Chiu, WC; Liu, JJ; Tsai, PH; Yeh, CL; Yeh, SL | 1 |
| Bagi, Z; Feher, A; Huang, A; Kaley, G; Sun, D; Yang, YM | 1 |
| Adams, SH | 1 |
| Cheng, KH; Chu, CS; Kuo, HF; Lai, WT; Lee, KT; Lee, MY; Lin, TH; Sheu, SH; Su, HM; Voon, WC | 1 |
| Barnini, S; Boggi, U; D'Aleo, V; Del Guerra, S; Del Prato, S; Filipponi, F; Gualtierotti, G; Lupi, R; Pandolfi, R; Vistoli, F | 1 |
| Boller, S; Boschetti, N; Item, F; Joblin, BA; Niessen, M; Spinas, GA; Trüb, T; Xu, L | 1 |
| Coucha, M; Ergul, A; Johnson, M; Kelly-Cobbs, AI; Knight, RA; Li, W; Ogbi, SN; Prakash, R | 1 |
| Chou, KC; Ma, Y; Wang, RL; Wang, SQ; Xu, WR | 1 |
| Ali, A; Barnett, AH; Begum, S; Dubb, K; Jose, B; Mughal, S; Piya, MK; Raymond, NT; Stevens, MJ; Tahrani, AA | 1 |
| Dyukova, E; Lupachyk, S; Obrosova, IG; Shevalye, H; Stavniichuk, R; Watcho, P | 1 |
| Adams-Huet, B; Chen, X; Devaraj, S; Jialal, I; Kaur, H | 1 |
| Feng, Y; Gao, Z; Huang, Y; Li, H; Li, X; Lu, N | 1 |
| Hwang, SM; Kang, DG; Kim, JS; Lee, HS; Lee, SM; Lee, YJ; Yoon, JJ | 1 |
| Gupta, AK; Kailashiya, J; Kumar, N; Singh, SK; Verma, AK | 1 |
| Bianchi, C; Chu, LM; Clements, RT; Dobrilovic, N; Feng, J; Fingleton, JG; Liu, Y; Sellke, FW; Singh, AK | 1 |
| Feldman, EL; Hinder, LM; McLean, LL; Pennathur, S; Vivekanandan-Giri, A | 1 |
| Basic, J; Cvetkovic, T; Djordjevic, G; Djordjevic, V; Ljubisavljevic, S; Pavlovic, D; Pavlovic, R; Stojanovic, I; Zabar, K | 1 |
| Raleigh, DP; Tu, LH | 1 |
| Bloch, W; Brixius, K; Reuter, H; Schwinger, RH; Streit, U; Wahlers, T | 1 |
| Barbieri, M; Boccardi, V; Esposito, A; Marfella, R; Pansini, A; Paolisso, G; Rizzo, MR | 1 |
| Bais, B; Catone, B; Ceriello, A; Marra, G; Motz, E; Pascon, R; Piazzola, M; Quagliaro, L; Taboga, C; Tonutti, L | 1 |
| Bais, B; Ceriello, A; Da Ros, R; Motz, E; Piconi, L; Quagliaro, L; Taboga, C; Tonutti, L | 1 |
| Horton, ES; Komjáti, K; Krolewski, AS; LoGerfo, FW; Pacher, P; Quist, WC; Szabó, C; Veves, A; Zanchi, A | 1 |
| Covino, ND; Hubbard, SR; Li, S; Stein, EG; Till, JH | 1 |
| Ciaraldi, TP; Henry, RR; Kahn, BB; Kim, YB; Kotani, K | 1 |
| DeFronzo, RA; He, H; Mandarino, LJ; Miyazaki, Y | 1 |
| Aytug, S; Begum, N; Bernstein, D; Reich, D; Sapiro, LE | 1 |
| Bailey, CJ; Flatt, PR; Gault, VA; Green, BD; Greer, B; Harriott, P; Irwin, N; Mooney, MH; O'Harte, FP | 1 |
| Bassett, ML; Cadet, E; Carter, K; David, V; Jouanolle, AM; Livesey, KJ; Merryweather-Clarke, AT; Mosser, A; Pointon, JJ; Poulton, J; Roberts, AG; Robson, KJ; Rochette, J; Wimhurst, VL; Worwood, M | 1 |
| Fujie, H; Kimura, S; Koike, K; Miyoshi, H; Moriya, K; Shintani, Y; Tsukamoto, K; Tsutsumi, T | 1 |
| Abu El-Asrar, AM; Dralands, L; Geboes, K; Meersschaert, A; Missotten, L | 1 |
| Freund, GG; Godbout, JP; Hartman, ME; Mazzocco, VR; Minor, KD; O'Connor, JC | 1 |
| Chen, MW; Liu, SQ; Sun, HY; Wang, CJ; Wang, YM; Xu, XP; Yang, MG; Zhang, Q | 1 |
| Assaloni, R; Ceriello, A; Da Ros, R; Esposito, K; Giugliano, D; Maier, A; Piconi, L; Quagliaro, L | 1 |
| Baldi, A; Baldi, F; Barboso, G; Cuzzocrea, S; D'Amico, M; Di Filippo, C; Di Marino, MP; Esposito, K; Giugliano, D; Marfella, R; Nappo, F; Portoghese, M; Rossi, F; Sasso, FC; Siniscalchi, M | 1 |
| Efrat, S; Gazit, E; Mazor, Y; Porat, Y | 1 |
| Kaduce, TL; Lee, HC; Spector, AA; Wang, XL; Zhou, W | 1 |
| Boggi, U; Bugliani, M; Del Guerra, S; Del Prato, S; Lupi, R; Marchetti, P; Marselli, L; Masini, M; Mosca, F; Pollera, M; Sbrana, S; Torri, S | 1 |
| Al-Mulla, F; Al-Saleh, E; Bitar, MS; Dhaunsi, GS; Mustafa, S; Wahid, S | 1 |
| Adrogue, JV; Brown, KK; Burgmaier, M; Golfman, LS; Guthrie, PH; Sharma, S; Taegtmeyer, H; Van Arsdall, M; Wilson, CR; Young, ME | 1 |
| Bergman, R; Bouchard, C; Kesäniemi, YA; Leon, AS; Rankinen, T; Rao, DC; Santaniemi, M; Skinner, JS; Ukkola, O; Wilmore, JH | 1 |
| Danielsson, A; Nystrom, FH; Ost, A; Strålfors, P | 1 |
| Belfort, R; Berria, R; De Filippis, EA; Finlayson, J; Kashyap, S; Mandarino, LJ; Pratipanawatr, T; Richardson, DK; Wang, L | 1 |
| Biró, Z; Ludány, A; Molnár, GA; Nemes, V; Wagner, Z; Wittmann, I | 1 |
| Angiolillo, D; Arora, U; Atar, D; Malinin, A; Pokov, A; Serebruany, V | 1 |
| Itoh, Y; Mori, Y; Obata, T; Tajima, N | 1 |
| Baldi, A; Chiorazzo, G; Cirillo, F; Coppola, L; Crescenzi, B; D'Amico, M; D'Andrea, F; Di Filippo, C; Marfella, R; Musacchio, E; Nicoletti, GF; Rossi, F; Sasso, FC; Siniscalchi, M; Verza, M | 1 |
| Champion, HC; Dugas, TR; Duranski, MR; Elrod, JW; Greer, JJ; Kevil, CG; Langston, W; Lefer, DJ; Tao, L | 1 |
| Ammendola, C; Cacciapuoti, F; Chiorazzo, G; Cinone, F; Coppola, L; D'Andrea, F; Liberti, D; Marchese, F; Marfella, MA; Marfella, R; Musacchio, E; Nicoletti, GF; Ruggiero, L; Sardu, C; Sasso, FC; Siniscalchi, M; Verza, M | 1 |
| Bito, Y; Kodai, S; Minamiyama, Y; Mizuguchi, S; Nishikawa, Y; Okada, S; Suehiro, S; Takahashi, Y; Takemura, S | 1 |
| Gohda, T; Gu, L; Hagiwara, S; Horikoshi, S; Kaneko, S; Matsumoto, M; Nakamura, S; Qian, J; Tanimoto, M; Tomino, Y; Zhang, M | 1 |
| Aoki, T; Gohda, T; Hagiwara, S; Horikoshi, S; Ito, T; Kaneko, S; Matsumoto, M; Murakoshi, M; Tanimoto, M; Tomino, Y; Yamada, K | 1 |
| Cameron, VA; Frampton, CM; Mocatta, TJ; Pilbrow, AP; Richards, AM; Senthilmohan, R; Winterbourn, CC | 1 |
| Boggi, U; Del Guerra, S; Del Prato, S; Filipponi, F; Lupi, R; Mancarella, R; Marchetti, P; Masiello, P; Mosca, F; Novelli, M; Paolini, M; Pedulli, GF; Soleti, A; Valgimigli, L | 1 |
| Ceriello, A; Corgnali, M; Darsow, T; Frias, JP; Lush, CW; Maggs, D; Nanayakkara, N; Piconi, L | 1 |
| Hong, G; Hughes, A; Lin, X; McCarthy, A; McCarthy, L; Mosteller, M; Sathe, G; Smart, D; Spraggs, C; Traini, C; Van Horn, S; Warren, L | 1 |
| D'Aleo, V; Lupi, R; Marchetti, P; Masiello, P; Novelli, M; Paolini, M; Soleti, A | 1 |
| Diessel, S; Forst, T; Hehenwarter, S; Hohberg, C; Larbig, M; Pfützner, A; Safinowski, M; Schöndorf, T; Weber, MM | 1 |
| Joshua, IG; Kartha, GK; Moshal, KS; Sen, U; Steed, MM; Tyagi, N; Tyagi, SC | 1 |
| Aoki, T; Gohda, T; Horikoshi, S; Kaneko, S; Matsumoto, M; Murakoshi, M; Tanimoto, M; Tomino, Y; Yamada, K; Yamazaki, T | 1 |
| Gawlowski, T; Götting, C; Kleesiek, K; Koschinsky, T; Negrean, M; Stirban, A; Stratmann, B; Tschoepe, D; Uribarri, J; Vlassara, H | 1 |
| Budavari, A; Hotamisligil, GS; Murray, D; Spiegelman, BM | 1 |
| Iida, M; Imanaka, T; Ito, K; Jinnouchi, H; Kamohara, S; Kan, M; Kanai, F; Nishioka, Y; Ohnishi, T; Todaka, M | 1 |
| Cardoso, AI; Llera, AS; Poskus, E; Stumpo, RR | 1 |
| Eriksson, JW; Jansson, PA; Posner, BI; Smith, U; Yu, ZW | 1 |
| Accili, D; Imai, Y; Philippe, N; Sesti, G; Taylor, SI | 1 |
| Babaya, N; Fujisawa, T; Hamada, Y; Ikegami, H; Kawabata, Y; Kawaguchi, Y; Nojima, K; Ogihara, T; Shen, GQ; Shintani, M; Ueda, H; Yamada, K | 1 |
| Ellard, S; Frayling, T; Grove, J; Hattersley, AT; Walker, M | 1 |
| Bach, JF; Boitard, C; Caillat-Zucman, S; Djilali-Saiah, I; Dubois-Laforgue, D; Larger, E; Mercadier, A; Timsit, J | 1 |
| Birnbacher, R; Herkner, K; Kampel, D; Krapfenbauer, K; Lubec, G; Vierhapper, H | 1 |
| Ahuja, S; Carter, R; Gerstein, HC; Kwan, T; Leber, B | 1 |
| Arcuri, P; Battista, P; Cama, A; Capani, F; Caramia, FG; Creati, B; Della Loggia, F; Esposito, DL; Mammarella, S; Mariani-Costantini, R | 1 |
| Boitard, C; Caillat-Zucman, S; Dubois-Laforgue, D; Timsit, J | 1 |
| Björnholm, M; Fahlman, R; Galuska, D; Jiang, XJ; Krook, A; Myers, MG; Wallberg-Henriksson, H; Zierath, JR | 1 |
| Anversa, P; Chimenti, C; Frustaci, A; Jakoniuk, I; Kajstura, J; Leri, A; Maseri, A; Nadal-Ginard, B | 1 |
| Begum, N; Ragolia, L; Sandu, OA | 1 |
| Aydin, A; Işimer, A; Orhan, H; Ozata, M; Sahin, G; Sayal, A | 1 |
| Miranker, AD; Padrick, SB | 1 |
| Aljada, A; Assian, E; Dandona, P; Garg, R; Ghanim, H; Hamouda, W; Mohanty, P | 1 |
| Abboud, HE; Choudhury, GG; Duch, J; Duraisamy, S; Faulkner, JL; Feliers, D; Kasinath, BS; Lee, AV | 1 |
| Assaloni, R; Ceriello, A; Mercuri, F; Motz, E; Quagliaro, L; Taboga, C; Tonutti, L | 1 |
| Adams, JM; Berria, R; Cusi, K; DeFronzo, RA; Jenkinson, CP; Maezono, K; Mandarino, LJ; Pratipanawatr, T; Pratipanawatr, W | 1 |
| Dash, D; Srivastava, K | 1 |
| Bonner-Weir, S; Kahn, CR; Meyerovitch, J; Rothenberg, P; Shechter, Y | 1 |
| Ciaraldi, TP; Freidenberg, GR; Molina, JM; Olefsky, JM; Thies, RS | 1 |
| Brillon, DJ; Freidenberg, GR; Henry, RR; Olefsky, JM | 1 |
| Ermel, B; Häring, H; Herberg, L; Hölzl, J; Kirsch, D; Machicao, F; Mushack, J; Obermaier, B; Rattenhuber, E; Su, Z | 1 |
| Benzi, L; Brunetti, A; Cecchetti, P; Marchetti, P; Navalesi, R; Trischitta, V; Vigneri, R | 1 |
7 review(s) available for tyrosine and Diabetes Mellitus, Adult-Onset
| Article | Year |
|---|---|
Protein tyrosine phosphatase 1B (PTP1B) as a potential therapeutic target for neurological disorders.
Topics: Aged; Anti-Inflammatory Agents; Brain-Derived Neurotrophic Factor; Diabetes Mellitus, Type 2; Enzyme Inhibitors; Humans; Insulin; Leptin; Nervous System Diseases; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Tyrosine | 2022 |
Antidiabetics, Anthelmintics, Statins, and Beta-Blockers as Co-Adjuvant Drugs in Cancer Therapy.
Topics: Adenosine Monophosphate; Adrenergic beta-Antagonists; Anthelmintics; Anti-Bacterial Agents; Antihypertensive Agents; Antimalarials; Antineoplastic Agents; Atorvastatin; Breast Neoplasms; Cholesterol; Diabetes Mellitus, Type 2; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemic Agents; Male; Mebendazole; Metformin; Mevalonic Acid; Propranolol; Protein Kinases; Proto-Oncogene Proteins B-raf; Receptors, Adrenergic, beta-2; Tyrosine | 2022 |
The potential role of lactulose pharmacotherapy in the treatment and prevention of diabetes.
Topics: Acarbose; Anti-Inflammatory Agents; Bacteria; Bile Acids and Salts; Diabetes Mellitus, Type 2; Fatty Acids, Volatile; Glucagon-Like Peptide 1; Humans; Lactulose; Laxatives; Lipopolysaccharides; Peptides; Tyrosine | 2022 |
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acrylic Resins; Actinobacillus; Acute Disease; Acute Kidney Injury; Adaptor Proteins, Signal Transducing; Adenosine; Adenosine Triphosphate; Administration, Inhalation; Administration, Oral; Adolescent; Adult; Advance Care Planning; Africa, Northern; Age Factors; Aged; Aged, 80 and over; Air Pollutants; Air Pollution; Air Pollution, Indoor; Albendazole; Aluminum Oxide; Anastomosis, Surgical; Ancylostoma; Ancylostomiasis; Androstadienes; Angiogenesis Inhibitors; Angiotensin II; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Antibodies, Bispecific; Antibodies, Viral; Anticoagulants; Antihypertensive Agents; Antinematodal Agents; Antineoplastic Agents; Antineoplastic Agents, Immunological; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Antiporters; Antiviral Agents; Apoptosis; Aptamers, Nucleotide; Aromatase Inhibitors; Asian People; Astrocytes; Atrial Fibrillation; Auditory Threshold; Aurora Kinase B; Australia; Autophagy; Autophagy-Related Protein 5; Autotrophic Processes; Bacillus cereus; Bacillus thuringiensis; Bacterial Proteins; Beclin-1; Belgium; Benzene; Benzene Derivatives; Benzhydryl Compounds; beta Catenin; beta-Arrestin 2; Biliary Tract Diseases; Biofilms; Biofuels; Biomarkers; Biomarkers, Tumor; Biomass; Biomechanical Phenomena; Bioreactors; Biosensing Techniques; Biosynthetic Pathways; Bismuth; Blood Platelets; Bone and Bones; Bone Regeneration; Bortezomib; Botulinum Toxins, Type A; Brain; Brain Injuries; Brain Ischemia; Brain Neoplasms; Breast Neoplasms; Breath Tests; Bronchodilator Agents; Calcium Phosphates; Cannabis; Carbon Dioxide; Carbon Isotopes; Carcinogenesis; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cardiac Resynchronization Therapy; Cardiac Resynchronization Therapy Devices; Cardiomyopathies; Cardiovascular Diseases; Cariostatic Agents; Case Managers; Case-Control Studies; Catalysis; Cation Transport Proteins; CD8-Positive T-Lymphocytes; Cecropia Plant; Cell Adhesion; Cell Count; Cell Differentiation; Cell Division; Cell Line; Cell Line, Tumor; Cell Membrane; Cell Movement; Cell Proliferation; Cell Self Renewal; Cell Survival; Cells, Cultured; Cellular Reprogramming; Cellulose; Charcoal; Chemical and Drug Induced Liver Injury; Chemical Phenomena; Chemokines; Chemoradiotherapy; Chemoreceptor Cells; Child; Child Abuse; Child, Preschool; China; Chlorogenic Acid; Chloroquine; Chromatography, Gas; Chronic Disease; Clinical Competence; Coated Materials, Biocompatible; Cochlea; Cohort Studies; Color; Comorbidity; Computer Simulation; Computer-Aided Design; Contraception; Contraceptive Agents, Female; Contrast Media; COP-Coated Vesicles; Coronavirus Infections; Cost of Illness; Coturnix; COVID-19; Creatinine; Cross-Over Studies; Cross-Sectional Studies; Culex; Curriculum; Cyclic N-Oxides; Cytokines; Cytoplasm; Cytotoxicity, Immunologic; Cytotoxins; Databases, Factual; Deep Learning; Delivery, Obstetric; Denitrification; Dental Caries; Denture, Complete; Dexamethasone; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dielectric Spectroscopy; Diet, High-Fat; Dietary Fiber; Disease Models, Animal; Disease Progression; DNA; DNA Copy Number Variations; DNA, Mitochondrial; Dog Diseases; Dogs; Dopaminergic Neurons; Double-Blind Method; Down-Regulation; Doxorubicin; Drug Carriers; Drug Design; Drug Interactions; Drug Resistance, Bacterial; Drug Resistance, Neoplasm; Drug-Related Side Effects and Adverse Reactions; Drugs, Chinese Herbal; Dry Powder Inhalers; Dust; E2F1 Transcription Factor; Ecosystem; Education, Nursing; Education, Nursing, Baccalaureate; Electric Impedance; Electricity; Electrocardiography; Electrochemical Techniques; Electrochemistry; Electrodes; Electrophoresis, Polyacrylamide Gel; Endoplasmic Reticulum; Endothelial Cells; Environmental Monitoring; Enzyme Inhibitors; Epithelial Cells; Epithelial-Mesenchymal Transition; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Estrogen Receptor Modulators; Europe; Evoked Potentials, Auditory, Brain Stem; Exosomes; Feasibility Studies; Female; Ferricyanides; Ferrocyanides; Fibrinogen; Finite Element Analysis; Fistula; Fluorescent Dyes; Fluorides, Topical; Fluorodeoxyglucose F18; Fluticasone; Follow-Up Studies; Food Contamination; Food Microbiology; Foods, Specialized; Forensic Medicine; Frail Elderly; France; Free Radicals; Fresh Water; Fungi; Fungicides, Industrial; Galactosamine; Gastrointestinal Neoplasms; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Frequency; Genetic Predisposition to Disease; Genotype; Gingival Hemorrhage; Glioblastoma; Glioma; Glomerular Filtration Rate; Glomerulosclerosis, Focal Segmental; Glucose; Glucose Transport Proteins, Facilitative; Glucosides; Glutamine; Glycolysis; Gold; GPI-Linked Proteins; Gram-Negative Bacteria; Gram-Positive Bacteria; Graphite; Haplotypes; HCT116 Cells; Healthy Volunteers; Hearing Loss; Heart Failure; Hedgehog Proteins; HEK293 Cells; HeLa Cells; Hemodynamics; Hemorrhage; Hepatocytes; Hippo Signaling Pathway; Histone Deacetylases; Homeostasis; Hospital Mortality; Hospitalization; Humans; Hydantoins; Hydrazines; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Hydroxylamines; Hypoglycemic Agents; Immunity, Innate; Immunoglobulin G; Immunohistochemistry; Immunologic Factors; Immunomodulation; Immunophenotyping; Immunotherapy; Incidence; Indazoles; Indonesia; Infant; Infant, Newborn; Infarction, Middle Cerebral Artery; Inflammation; Injections, Intramuscular; Insecticides; Insulin-Like Growth Factor I; Insurance, Health; Intention to Treat Analysis; Interleukin-1 Receptor-Associated Kinases; Interleukin-6; Intrauterine Devices; Intrauterine Devices, Copper; Iron; Ischemia; Jordan; Keratinocytes; Kidney; Kidney Diseases; Kir5.1 Channel; Klebsiella Infections; Klebsiella pneumoniae; Lab-On-A-Chip Devices; Laparoscopy; Lasers; Lasers, Semiconductor; Lenalidomide; Leptin; Lethal Dose 50; Levonorgestrel; Limit of Detection; Lipid Metabolism; Lipid Metabolism Disorders; Lipogenesis; Lipopolysaccharides; Liquid Biopsy; Liver; Liver Abscess, Pyogenic; Liver Cirrhosis; Liver Diseases; Liver Neoplasms; Longevity; Lung Neoplasms; Luteolin; Lymph Nodes; Lymphocyte Activation; Macaca fascicularis; Macrophages; Mad2 Proteins; Magnetic Resonance Imaging; Male; Mammary Glands, Human; Manganese; Manganese Compounds; MAP Kinase Signaling System; Materials Testing; Maternal Health Services; MCF-7 Cells; Medicaid; Medicine, Chinese Traditional; Melanoma; Membrane Proteins; Mental Health; Mercury; Metal Nanoparticles; Metals, Heavy; Metformin; Methionine Adenosyltransferase; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Knockout; Mice, Nude; Microalgae; Microbial Sensitivity Tests; Microglia; MicroRNAs; Microscopy, Atomic Force; Microscopy, Electron, Scanning; Middle Aged; Mitochondria; Mitochondrial Proteins; Mitral Valve; Mitral Valve Insufficiency; Models, Anatomic; Molecular Structure; Molybdenum; Monocarboxylic Acid Transporters; Moths; MPTP Poisoning; Multigene Family; Multiparametric Magnetic Resonance Imaging; Multiple Myeloma; Muscle, Skeletal; Mutagens; Mutation; Myeloid Cells; Nanocomposites; Nanofibers; Nanomedicine; Nanoparticles; Nanowires; Neoadjuvant Therapy; Neomycin; Neoplasm Grading; Neoplasm Recurrence, Local; Neoplasms; Neoplastic Stem Cells; Neostriatum; Neovascularization, Pathologic; Netherlands; Neuromuscular Agents; Neurons; NF-E2-Related Factor 2; NF-kappa B; Nickel; Nitrogen Oxides; Non-alcoholic Fatty Liver Disease; Nucleosides; Nucleotidyltransferases; Nutritional Status; Obesity, Morbid; Ofloxacin; Oils, Volatile; Oligopeptides; Oncogene Protein v-akt; Optical Imaging; Organic Cation Transport Proteins; Organophosphonates; Osteoarthritis; Osteoarthritis, Hip; Osteoarthritis, Knee; Osteoblasts; Osteogenesis; Oxidation-Reduction; Oxidative Stress; Oxides; Oxygen Isotopes; Pancreas; Pancreaticoduodenectomy; Pandemics; Particle Size; Particulate Matter; Patient Acceptance of Health Care; Patient Compliance; PC-3 Cells; Peptide Fragments; Peptides; Periodontal Attachment Loss; Periodontal Index; Periodontal Pocket; Periodontitis; Peroxides; Peru; Pest Control, Biological; Phosphatidylinositol 3-Kinase; Phosphatidylinositol 3-Kinases; Phylogeny; Pilot Projects; Piperidines; Plant Bark; Plant Extracts; Plant Leaves; Plasmids; Platelet Function Tests; Pneumonia, Viral; Podocytes; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Polyethylene Terephthalates; Polymers; Polymorphism, Single Nucleotide; Porosity; Portugal; Positron-Emission Tomography; Postoperative Complications; Postural Balance; Potassium Channels, Inwardly Rectifying; Povidone; Powders; Precancerous Conditions; Precision Medicine; Predictive Value of Tests; Pregnancy; Prenatal Care; Prognosis; Promoter Regions, Genetic; Prospective Studies; Prostatectomy; Prostatic Neoplasms; Proteasome Inhibitors; Protective Agents; Protein Binding; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Protein Transport; Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins c-akt; Psychiatric Nursing; PTEN Phosphohydrolase; Pulmonary Embolism; Pyrimethamine; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Rats, Wistar; Reactive Oxygen Species; Receptor, ErbB-2; Receptor, IGF Type 1; Receptors, Estrogen; Receptors, G-Protein-Coupled; Recombinational DNA Repair; Recovery of Function; Regional Blood Flow; Renal Dialysis; Renin; Renin-Angiotensin System; Reperfusion Injury; Reproducibility of Results; Republic of Korea; Respiratory Distress Syndrome; Retrospective Studies; Rhodamines; Risk Assessment; Risk Factors; RNA, Long Noncoding; RNA, Messenger; Running; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Salinity; Salmeterol Xinafoate; Sarcoma; Seasons; Shoulder Injuries; Signal Transduction; Silicon Dioxide; Silver; Sirtuin 1; Sirtuins; Skull Fractures; Social Determinants of Health; Sodium; Sodium Fluoride; Sodium Potassium Chloride Symporter Inhibitors; Sodium-Glucose Transporter 2 Inhibitors; Soil; Soil Pollutants; Spain; Spectrophotometry; Spectroscopy, Fourier Transform Infrared; Staphylococcal Protein A; Staphylococcus aureus; Stem Cells; Stereoisomerism; Stomach Neoplasms; Streptomyces; Strontium; Structure-Activity Relationship; Students, Nursing; Substance-Related Disorders; Succinic Acid; Sulfur; Surface Properties; Survival Rate; Survivin; Symporters; T-Lymphocytes; Temozolomide; Tensile Strength; Thiazoles; Thiobacillus; Thiohydantoins; Thiourea; Thrombectomy; Time Factors; Titanium; Tobacco Mosaic Virus; Tobacco Use Disorder; Toll-Like Receptor 4; Toluene; Tomography, X-Ray Computed; TOR Serine-Threonine Kinases; Toxicity Tests, Acute; Toxicity Tests, Subacute; Transcriptional Activation; Treatment Outcome; Troponin I; Tumor Cells, Cultured; Tumor Escape; Tumor Hypoxia; Tumor Microenvironment; Tumor Necrosis Factor Inhibitors; Tumor Necrosis Factor-alpha; Tyrosine; Ubiquitin-Protein Ligases; Ubiquitination; Ultrasonic Waves; United Kingdom; United States; United States Department of Veterans Affairs; Up-Regulation; Urea; Uric Acid; Urinary Bladder Neoplasms; Urinary Bladder, Neurogenic; Urine; Urodynamics; User-Computer Interface; Vemurafenib; Verbenaceae; Veterans; Veterans Health; Viral Load; Virtual Reality; Vitiligo; Water Pollutants, Chemical; Wildfires; Wnt Signaling Pathway; Wound Healing; X-Ray Diffraction; Xenograft Model Antitumor Assays; Xylenes; Young Adult; Zinc; Zinc Oxide; Zinc Sulfate; Zoonoses | 2021 |
Effect of Insulin Resistance on Monounsaturated Fatty Acid Levels: A Multi-cohort Non-targeted Metabolomics and Mendelian Randomization Study.
Topics: Adult; Aged; Aged, 80 and over; Bile Acids and Salts; Caffeine; Diabetes Mellitus, Type 2; Fatty Acids, Monounsaturated; Glucose; Glucose Tolerance Test; Glycerophospholipids; Humans; Insulin; Insulin Resistance; Insulin Secretion; Male; Metabolic Networks and Pathways; Metabolomics; Middle Aged; Tyrosine | 2016 |
Emerging perspectives on essential amino acid metabolism in obesity and the insulin-resistant state.
Topics: 3-Methyl-2-Oxobutanoate Dehydrogenase (Lipoamide); Amino Acids, Aromatic; Amino Acids, Sulfur; Animals; Cysteine; Cystine; Diabetes Mellitus, Type 2; Humans; Insulin Resistance; Methionine; Models, Biological; Obesity; Oxidation-Reduction; Oxidative Stress; Phenylalanine; Transaminases; Tyrosine | 2011 |
From signal transduction to signal interpretation: an alternative model for the molecular function of insulin receptor substrates.
Topics: Animals; Binding Sites; Diabetes Mellitus, Type 2; Gene Expression Regulation; Humans; Insulin Receptor Substrate Proteins; Insulin Resistance; Models, Biological; Protein Binding; Protein Structure, Tertiary; Receptor, Insulin; Signal Transduction; Tyrosine | 2012 |
21 trial(s) available for tyrosine and Diabetes Mellitus, Adult-Onset
| Article | Year |
|---|---|
Psychological distress among health care professionals of the three COVID-19 most affected Regions in Cameroon: Prevalence and associated factors.
Topics: 3' Untranslated Regions; 5'-Nucleotidase; A549 Cells; Accidental Falls; Acetylcholinesterase; Acrylic Resins; Actinobacillus; Acute Disease; Acute Kidney Injury; Adaptor Proteins, Signal Transducing; Adenosine; Adenosine Triphosphate; Administration, Inhalation; Administration, Oral; Adolescent; Adult; Advance Care Planning; Africa, Northern; Age Factors; Aged; Aged, 80 and over; Air Pollutants; Air Pollution; Air Pollution, Indoor; Albendazole; Aluminum Oxide; Anastomosis, Surgical; Ancylostoma; Ancylostomiasis; Androstadienes; Angiogenesis Inhibitors; Angiotensin II; Animals; Anti-Bacterial Agents; Anti-Infective Agents; Antibodies, Bispecific; Antibodies, Viral; Anticoagulants; Antihypertensive Agents; Antinematodal Agents; Antineoplastic Agents; Antineoplastic Agents, Immunological; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Antiporters; Antiviral Agents; Apoptosis; Aptamers, Nucleotide; Aromatase Inhibitors; Asian People; Astrocytes; Atrial Fibrillation; Auditory Threshold; Aurora Kinase B; Australia; Autophagy; Autophagy-Related Protein 5; Autotrophic Processes; Bacillus cereus; Bacillus thuringiensis; Bacterial Proteins; Beclin-1; Belgium; Benzene; Benzene Derivatives; Benzhydryl Compounds; beta Catenin; beta-Arrestin 2; Biliary Tract Diseases; Biofilms; Biofuels; Biomarkers; Biomarkers, Tumor; Biomass; Biomechanical Phenomena; Bioreactors; Biosensing Techniques; Biosynthetic Pathways; Bismuth; Blood Platelets; Bone and Bones; Bone Regeneration; Bortezomib; Botulinum Toxins, Type A; Brain; Brain Injuries; Brain Ischemia; Brain Neoplasms; Breast Neoplasms; Breath Tests; Bronchodilator Agents; Calcium Phosphates; Cannabis; Carbon Dioxide; Carbon Isotopes; Carcinogenesis; Carcinoma, Hepatocellular; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cardiac Resynchronization Therapy; Cardiac Resynchronization Therapy Devices; Cardiomyopathies; Cardiovascular Diseases; Cariostatic Agents; Case Managers; Case-Control Studies; Catalysis; Cation Transport Proteins; CD8-Positive T-Lymphocytes; Cecropia Plant; Cell Adhesion; Cell Count; Cell Differentiation; Cell Division; Cell Line; Cell Line, Tumor; Cell Membrane; Cell Movement; Cell Proliferation; Cell Self Renewal; Cell Survival; Cells, Cultured; Cellular Reprogramming; Cellulose; Charcoal; Chemical and Drug Induced Liver Injury; Chemical Phenomena; Chemokines; Chemoradiotherapy; Chemoreceptor Cells; Child; Child Abuse; Child, Preschool; China; Chlorogenic Acid; Chloroquine; Chromatography, Gas; Chronic Disease; Clinical Competence; Coated Materials, Biocompatible; Cochlea; Cohort Studies; Color; Comorbidity; Computer Simulation; Computer-Aided Design; Contraception; Contraceptive Agents, Female; Contrast Media; COP-Coated Vesicles; Coronavirus Infections; Cost of Illness; Coturnix; COVID-19; Creatinine; Cross-Over Studies; Cross-Sectional Studies; Culex; Curriculum; Cyclic N-Oxides; Cytokines; Cytoplasm; Cytotoxicity, Immunologic; Cytotoxins; Databases, Factual; Deep Learning; Delivery, Obstetric; Denitrification; Dental Caries; Denture, Complete; Dexamethasone; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dielectric Spectroscopy; Diet, High-Fat; Dietary Fiber; Disease Models, Animal; Disease Progression; DNA; DNA Copy Number Variations; DNA, Mitochondrial; Dog Diseases; Dogs; Dopaminergic Neurons; Double-Blind Method; Down-Regulation; Doxorubicin; Drug Carriers; Drug Design; Drug Interactions; Drug Resistance, Bacterial; Drug Resistance, Neoplasm; Drug-Related Side Effects and Adverse Reactions; Drugs, Chinese Herbal; Dry Powder Inhalers; Dust; E2F1 Transcription Factor; Ecosystem; Education, Nursing; Education, Nursing, Baccalaureate; Electric Impedance; Electricity; Electrocardiography; Electrochemical Techniques; Electrochemistry; Electrodes; Electrophoresis, Polyacrylamide Gel; Endoplasmic Reticulum; Endothelial Cells; Environmental Monitoring; Enzyme Inhibitors; Epithelial Cells; Epithelial-Mesenchymal Transition; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Estrogen Receptor Modulators; Europe; Evoked Potentials, Auditory, Brain Stem; Exosomes; Feasibility Studies; Female; Ferricyanides; Ferrocyanides; Fibrinogen; Finite Element Analysis; Fistula; Fluorescent Dyes; Fluorides, Topical; Fluorodeoxyglucose F18; Fluticasone; Follow-Up Studies; Food Contamination; Food Microbiology; Foods, Specialized; Forensic Medicine; Frail Elderly; France; Free Radicals; Fresh Water; Fungi; Fungicides, Industrial; Galactosamine; Gastrointestinal Neoplasms; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Frequency; Genetic Predisposition to Disease; Genotype; Gingival Hemorrhage; Glioblastoma; Glioma; Glomerular Filtration Rate; Glomerulosclerosis, Focal Segmental; Glucose; Glucose Transport Proteins, Facilitative; Glucosides; Glutamine; Glycolysis; Gold; GPI-Linked Proteins; Gram-Negative Bacteria; Gram-Positive Bacteria; Graphite; Haplotypes; HCT116 Cells; Healthy Volunteers; Hearing Loss; Heart Failure; Hedgehog Proteins; HEK293 Cells; HeLa Cells; Hemodynamics; Hemorrhage; Hepatocytes; Hippo Signaling Pathway; Histone Deacetylases; Homeostasis; Hospital Mortality; Hospitalization; Humans; Hydantoins; Hydrazines; Hydrogen Peroxide; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Hydroxylamines; Hypoglycemic Agents; Immunity, Innate; Immunoglobulin G; Immunohistochemistry; Immunologic Factors; Immunomodulation; Immunophenotyping; Immunotherapy; Incidence; Indazoles; Indonesia; Infant; Infant, Newborn; Infarction, Middle Cerebral Artery; Inflammation; Injections, Intramuscular; Insecticides; Insulin-Like Growth Factor I; Insurance, Health; Intention to Treat Analysis; Interleukin-1 Receptor-Associated Kinases; Interleukin-6; Intrauterine Devices; Intrauterine Devices, Copper; Iron; Ischemia; Jordan; Keratinocytes; Kidney; Kidney Diseases; Kir5.1 Channel; Klebsiella Infections; Klebsiella pneumoniae; Lab-On-A-Chip Devices; Laparoscopy; Lasers; Lasers, Semiconductor; Lenalidomide; Leptin; Lethal Dose 50; Levonorgestrel; Limit of Detection; Lipid Metabolism; Lipid Metabolism Disorders; Lipogenesis; Lipopolysaccharides; Liquid Biopsy; Liver; Liver Abscess, Pyogenic; Liver Cirrhosis; Liver Diseases; Liver Neoplasms; Longevity; Lung Neoplasms; Luteolin; Lymph Nodes; Lymphocyte Activation; Macaca fascicularis; Macrophages; Mad2 Proteins; Magnetic Resonance Imaging; Male; Mammary Glands, Human; Manganese; Manganese Compounds; MAP Kinase Signaling System; Materials Testing; Maternal Health Services; MCF-7 Cells; Medicaid; Medicine, Chinese Traditional; Melanoma; Membrane Proteins; Mental Health; Mercury; Metal Nanoparticles; Metals, Heavy; Metformin; Methionine Adenosyltransferase; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Knockout; Mice, Nude; Microalgae; Microbial Sensitivity Tests; Microglia; MicroRNAs; Microscopy, Atomic Force; Microscopy, Electron, Scanning; Middle Aged; Mitochondria; Mitochondrial Proteins; Mitral Valve; Mitral Valve Insufficiency; Models, Anatomic; Molecular Structure; Molybdenum; Monocarboxylic Acid Transporters; Moths; MPTP Poisoning; Multigene Family; Multiparametric Magnetic Resonance Imaging; Multiple Myeloma; Muscle, Skeletal; Mutagens; Mutation; Myeloid Cells; Nanocomposites; Nanofibers; Nanomedicine; Nanoparticles; Nanowires; Neoadjuvant Therapy; Neomycin; Neoplasm Grading; Neoplasm Recurrence, Local; Neoplasms; Neoplastic Stem Cells; Neostriatum; Neovascularization, Pathologic; Netherlands; Neuromuscular Agents; Neurons; NF-E2-Related Factor 2; NF-kappa B; Nickel; Nitrogen Oxides; Non-alcoholic Fatty Liver Disease; Nucleosides; Nucleotidyltransferases; Nutritional Status; Obesity, Morbid; Ofloxacin; Oils, Volatile; Oligopeptides; Oncogene Protein v-akt; Optical Imaging; Organic Cation Transport Proteins; Organophosphonates; Osteoarthritis; Osteoarthritis, Hip; Osteoarthritis, Knee; Osteoblasts; Osteogenesis; Oxidation-Reduction; Oxidative Stress; Oxides; Oxygen Isotopes; Pancreas; Pancreaticoduodenectomy; Pandemics; Particle Size; Particulate Matter; Patient Acceptance of Health Care; Patient Compliance; PC-3 Cells; Peptide Fragments; Peptides; Periodontal Attachment Loss; Periodontal Index; Periodontal Pocket; Periodontitis; Peroxides; Peru; Pest Control, Biological; Phosphatidylinositol 3-Kinase; Phosphatidylinositol 3-Kinases; Phylogeny; Pilot Projects; Piperidines; Plant Bark; Plant Extracts; Plant Leaves; Plasmids; Platelet Function Tests; Pneumonia, Viral; Podocytes; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Polyethylene Terephthalates; Polymers; Polymorphism, Single Nucleotide; Porosity; Portugal; Positron-Emission Tomography; Postoperative Complications; Postural Balance; Potassium Channels, Inwardly Rectifying; Povidone; Powders; Precancerous Conditions; Precision Medicine; Predictive Value of Tests; Pregnancy; Prenatal Care; Prognosis; Promoter Regions, Genetic; Prospective Studies; Prostatectomy; Prostatic Neoplasms; Proteasome Inhibitors; Protective Agents; Protein Binding; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Protein Transport; Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins c-akt; Psychiatric Nursing; PTEN Phosphohydrolase; Pulmonary Embolism; Pyrimethamine; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Rats, Wistar; Reactive Oxygen Species; Receptor, ErbB-2; Receptor, IGF Type 1; Receptors, Estrogen; Receptors, G-Protein-Coupled; Recombinational DNA Repair; Recovery of Function; Regional Blood Flow; Renal Dialysis; Renin; Renin-Angiotensin System; Reperfusion Injury; Reproducibility of Results; Republic of Korea; Respiratory Distress Syndrome; Retrospective Studies; Rhodamines; Risk Assessment; Risk Factors; RNA, Long Noncoding; RNA, Messenger; Running; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Salinity; Salmeterol Xinafoate; Sarcoma; Seasons; Shoulder Injuries; Signal Transduction; Silicon Dioxide; Silver; Sirtuin 1; Sirtuins; Skull Fractures; Social Determinants of Health; Sodium; Sodium Fluoride; Sodium Potassium Chloride Symporter Inhibitors; Sodium-Glucose Transporter 2 Inhibitors; Soil; Soil Pollutants; Spain; Spectrophotometry; Spectroscopy, Fourier Transform Infrared; Staphylococcal Protein A; Staphylococcus aureus; Stem Cells; Stereoisomerism; Stomach Neoplasms; Streptomyces; Strontium; Structure-Activity Relationship; Students, Nursing; Substance-Related Disorders; Succinic Acid; Sulfur; Surface Properties; Survival Rate; Survivin; Symporters; T-Lymphocytes; Temozolomide; Tensile Strength; Thiazoles; Thiobacillus; Thiohydantoins; Thiourea; Thrombectomy; Time Factors; Titanium; Tobacco Mosaic Virus; Tobacco Use Disorder; Toll-Like Receptor 4; Toluene; Tomography, X-Ray Computed; TOR Serine-Threonine Kinases; Toxicity Tests, Acute; Toxicity Tests, Subacute; Transcriptional Activation; Treatment Outcome; Troponin I; Tumor Cells, Cultured; Tumor Escape; Tumor Hypoxia; Tumor Microenvironment; Tumor Necrosis Factor Inhibitors; Tumor Necrosis Factor-alpha; Tyrosine; Ubiquitin-Protein Ligases; Ubiquitination; Ultrasonic Waves; United Kingdom; United States; United States Department of Veterans Affairs; Up-Regulation; Urea; Uric Acid; Urinary Bladder Neoplasms; Urinary Bladder, Neurogenic; Urine; Urodynamics; User-Computer Interface; Vemurafenib; Verbenaceae; Veterans; Veterans Health; Viral Load; Virtual Reality; Vitiligo; Water Pollutants, Chemical; Wildfires; Wnt Signaling Pathway; Wound Healing; X-Ray Diffraction; Xenograft Model Antitumor Assays; Xylenes; Young Adult; Zinc; Zinc Oxide; Zinc Sulfate; Zoonoses | 2021 |
Metabolites and diabetes remission after weight loss.
Topics: Amino Acids, Branched-Chain; Bariatric Surgery; Betaine; Biomarkers; Choline; Diabetes Mellitus, Type 2; Female; Humans; Male; Mass Spectrometry; Methylamines; Middle Aged; Obesity; Obesity, Morbid; Remission Induction; Treatment Outcome; Tyrosine; Weight Loss | 2021 |
Effect of metformin on plasma metabolite profile in the Copenhagen Insulin and Metformin Therapy (CIMT) trial.
Topics: Aged; Carnitine; Chromatography, Liquid; Diabetes Mellitus, Type 2; Female; Follow-Up Studies; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Insulin Resistance; Isoleucine; Leucine; Lysophospholipids; Male; Mass Spectrometry; Metabolome; Metabolomics; Metformin; Middle Aged; Mitochondria; Tyrosine; Valine | 2018 |
Impact of rosiglitazone and glyburide on nitrosative stress and myocardial blood flow regulation in type 2 diabetes mellitus.
Topics: Adiponectin; Adult; Blood Glucose; C-Reactive Protein; Cohort Studies; Coronary Vessels; Diabetes Mellitus, Type 2; Endothelium, Vascular; Female; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Lipid Metabolism; Male; Middle Aged; Myocardium; Positron-Emission Tomography; Reactive Nitrogen Species; Rosiglitazone; Thiazolidinediones; Tyrosine; von Willebrand Factor | 2009 |
Postprandial vascular effects of VIAject compared with insulin lispro and regular human insulin in patients with type 2 diabetes.
Topics: Arginine; Blood Glucose; Blood Vessels; Diabetes Mellitus, Type 2; Female; Humans; Hypoglycemic Agents; Injections, Subcutaneous; Insulin; Insulin Lispro; Male; Microcirculation; Middle Aged; Postprandial Period; Tyrosine | 2010 |
Effect of Irbesartan treatment on plasma and urinary markers of protein damage in patients with type 2 diabetes and microalbuminuria.
Topics: Albuminuria; Amino Acids; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Bendroflumethiazide; Biomarkers; Biphenyl Compounds; Cross-Over Studies; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Dose-Response Relationship, Drug; Female; Glycation End Products, Advanced; Glycosylation; Humans; Hypertension; Irbesartan; Male; Oxidative Stress; Tetrazoles; Tyrosine | 2012 |
Resveratrol improves insulin sensitivity, reduces oxidative stress and activates the Akt pathway in type 2 diabetic patients.
Topics: Adult; Blood Platelets; Diabetes Mellitus, Type 2; Double-Blind Method; Humans; Insulin Resistance; Male; Middle Aged; Oxidative Stress; Phytotherapy; Plant Extracts; Proto-Oncogene Proteins c-akt; Resveratrol; Signal Transduction; Stilbenes; Tyrosine | 2011 |
Effect of a fatty meal on inflammatory markers in healthy volunteers with a family history of type 2 diabetes.
Topics: Biomarkers; Case-Control Studies; CD40 Ligand; Cytokines; Diabetes Mellitus, Type 2; Dietary Fats; Endothelium, Vascular; Family; Fasting; Genetic Predisposition to Disease; Humans; Inflammation Mediators; Intercellular Adhesion Molecule-1; Lipids; Postprandial Period; Reference Values; Risk Factors; RNA, Messenger; Tyrosine; Vascular Cell Adhesion Molecule-1 | 2011 |
Reduction of circulating superoxide dismutase activity in type 2 diabetic patients with microalbuminuria and its modulation by telmisartan therapy.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Aged; Albuminuria; Angiotensin II Type 1 Receptor Blockers; Antioxidants; Benzimidazoles; Benzoates; Cross-Over Studies; Deoxyguanosine; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Humans; Japan; Losartan; Male; Middle Aged; Nitric Oxide; Oxidative Stress; Superoxide Dismutase; Telmisartan; Tyrosine | 2011 |
Decreased carotid atherosclerotic process by control of daily acute glucose fluctuations in diabetic patients treated by DPP-IV inhibitors.
Topics: Adamantane; Atherosclerosis; Blood Glucose; Carotid Arteries; Carotid Artery Diseases; Carotid Intima-Media Thickness; Cytokines; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Glycated Hemoglobin; Humans; Inflammation; Nitriles; Oxidative Stress; Prospective Studies; Pyrazines; Pyrrolidines; Sitagliptin Phosphate; Triazoles; Tyrosine; Vildagliptin | 2013 |
Evidence for an independent and cumulative effect of postprandial hypertriglyceridemia and hyperglycemia on endothelial dysfunction and oxidative stress generation: effects of short- and long-term simvastatin treatment.
Topics: Blood Glucose; Cardiovascular Diseases; Cross-Over Studies; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Administration Schedule; Endothelium, Vascular; Female; Glucose Tolerance Test; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertriglyceridemia; Male; Middle Aged; Oxidative Stress; Postprandial Period; Risk Factors; Simvastatin; Triglycerides; Tyrosine; Vasodilation | 2002 |
Poly(ADP-Ribose) polymerase is activated in subjects at risk of developing type 2 diabetes and is associated with impaired vascular reactivity.
Topics: Acetylcholine; Biopsy; Cell Nucleus; Diabetes Mellitus, Type 2; Disease Progression; Endothelium, Vascular; Enzyme Activation; Female; Forearm; Humans; Immunohistochemistry; Male; Microcirculation; Middle Aged; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Platelet Endothelial Cell Adhesion Molecule-1; Poly(ADP-ribose) Polymerases; Polymorphism, Genetic; Predictive Value of Tests; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Reference Values; Risk Assessment; Skin; Statistics as Topic; Tyrosine | 2002 |
Rosiglitazone improves downstream insulin receptor signaling in type 2 diabetic patients.
Topics: Biopsy; Blood Glucose; Diabetes Mellitus, Type 2; Fatty Acids, Nonesterified; Female; Glucose Clamp Technique; Glucose Intolerance; Humans; Hypoglycemic Agents; Insulin; Insulin Receptor Substrate Proteins; Insulin Secretion; Male; Middle Aged; Muscle, Skeletal; Phosphoproteins; Phosphorylation; Receptor, Insulin; Rosiglitazone; Signal Transduction; Thiazoles; Thiazolidinediones; Tyrosine | 2003 |
Effect of irbesartan on nitrotyrosine generation in non-hypertensive diabetic patients.
Topics: Antihypertensive Agents; Biphenyl Compounds; Blood Glucose; Blood Pressure; Cross-Over Studies; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Humans; Irbesartan; Male; Middle Aged; Placebos; Tetrazoles; Tyrosine | 2004 |
Effects of pioglitazone vs glibenclamide on postprandial increases in glucose and triglyceride levels and on oxidative stress in Japanese patients with type 2 diabetes.
Topics: Aged; Blood Glucose; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Fatty Acids, Nonesterified; Female; Glyburide; Glycated Hemoglobin; Humans; Hyperglycemia; Hyperlipidemias; Hypoglycemic Agents; Insulin; Insulin Resistance; Lipoprotein Lipase; Male; Middle Aged; Oxidative Stress; Pioglitazone; Postprandial Period; Thiazolidinediones; Time Factors; Triglycerides; Tyrosine | 2006 |
Effect of moderate red wine intake on cardiac prognosis after recent acute myocardial infarction of subjects with Type 2 diabetes mellitus.
Topics: Adult; Aged; C-Reactive Protein; Cardiovascular Diseases; Cytokines; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diet, Mediterranean; Follow-Up Studies; Heart; Humans; Middle Aged; Myocardial Infarction; Oxidative Stress; Prognosis; Treatment Outcome; Tyrosine; Wine | 2006 |
Pramlintide reduced markers of oxidative stress in the postprandial period in patients with type 2 diabetes.
Topics: Adolescent; Adult; Amyloid; Biomarkers; Blood Glucose; Cholesterol, LDL; Diabetes Mellitus, Type 2; Female; Humans; Insulin; Insulin Lispro; Islet Amyloid Polypeptide; Male; Middle Aged; Oxidative Stress; Postprandial Period; Single-Blind Method; Tyrosine | 2008 |
Genetic variants in the epithelial sodium channel associate with oedema in type 2 diabetic patients receiving the peroxisome proliferator-activated receptor gamma agonist farglitazar.
Topics: Adult; Aged; Base Sequence; Diabetes Mellitus, Type 2; DNA Primers; Edema; Epithelial Sodium Channels; Female; Genes, Reporter; Genetic Variation; Humans; Male; Middle Aged; Oxazoles; Pharmacogenetics; Phenotype; PPAR gamma; Promoter Regions, Genetic; Risk Factors; Time Factors; Tyrosine | 2007 |
Effect of insulin glulisine on microvascular blood flow and endothelial function in the postprandial state.
Topics: Adult; Aged; Blood Flow Velocity; Cross-Over Studies; Diabetes Mellitus, Type 2; Endothelium, Vascular; Female; Humans; Hypoglycemic Agents; Insulin; Laser-Doppler Flowmetry; Male; Microcirculation; Middle Aged; Patient Selection; Postprandial Period; Proinsulin; Tyrosine | 2008 |
Nuclear factor-kappaB suppressive and inhibitor-kappaB stimulatory effects of troglitazone in obese patients with type 2 diabetes: evidence of an antiinflammatory action?
Topics: Adult; Anti-Inflammatory Agents; Blood Glucose; C-Reactive Protein; Chemokine CCL2; Cholesterol; Chromans; Diabetes Mellitus; Diabetes Mellitus, Type 2; Female; Humans; I-kappa B Proteins; Insulin; Intercellular Adhesion Molecule-1; Leukocytes, Mononuclear; Linoleic Acid; Linoleic Acids; Linoleic Acids, Conjugated; Male; Middle Aged; NADPH Oxidases; Neutrophils; NF-kappa B; Obesity; Phenylalanine; Phosphoproteins; Plasminogen Activator Inhibitor 1; Reactive Oxygen Species; Thiazoles; Thiazolidinediones; Triglycerides; Troglitazone; Tyrosine | 2001 |
Insulin-receptor autophosphorylation and endogenous substrate phosphorylation in human adipocytes from control, obese, and NIDDM subjects.
Topics: Adipose Tissue; Adult; Animals; Biological Transport; Cell Fractionation; Diabetes Mellitus; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Glucose; Humans; Hydrogen Peroxide; Immunoblotting; Insulin; Insulin Resistance; Membrane Proteins; Obesity; Phosphorylation; Protein-Tyrosine Kinases; Rats; Rats, Inbred Strains; Receptor, Insulin; Temperature; Tyrosine; Vanadates; Wheat Germ Agglutinins | 1990 |
135 other study(ies) available for tyrosine and Diabetes Mellitus, Adult-Onset
| Article | Year |
|---|---|
Luteolin Improves Perivascular Adipose Tissue Profile and Vascular Dysfunction in Goto-Kakizaki Rats.
Topics: Adipose Tissue; Animals; Carrier Proteins; Chemokine CCL2; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Disease Models, Animal; Drug Administration Schedule; Endothelium, Vascular; Luteolin; Male; Oxidative Stress; Rats; Rats, Wistar; Tyrosine | 2021 |
Glutamic Acid Decarboxylase and Tyrosine Phosphatase-Related Islet Antigen-2 Positivity among Children and Adolescents with Diabetes in Korea.
Topics: Adolescent; Autoantibodies; Child; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Glutamate Decarboxylase; Humans; Insulin; Republic of Korea; Retrospective Studies; Tyrosine | 2022 |
The alpha-7 nicotinic acetylcholine receptor agonist GTS-21 engages the glucagon-like peptide-1 incretin hormone axis to lower levels of blood glucose in db/db mice.
Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Benzylidene Compounds; Blood Glucose; Diabetes Mellitus, Type 2; Female; Gastric Inhibitory Polypeptide; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucose Tolerance Test; Humans; Incretins; Insulin; Insulin Resistance; Male; Mice; Mice, Knockout; Nicotinic Agonists; Pyridines; Sitagliptin Phosphate; Tyrosine | 2022 |
Oxidative Damage by 3-nitrotyrosine in Young Adults with Obesity: Its Implication in Chronic and Contagious Diseases.
Topics: Adolescent; Adult; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Male; Obesity; Oxidative Stress; Tyrosine; Young Adult | 2023 |
In vivo drug discovery for increasing incretin-expressing cells identifies DYRK inhibitors that reinforce the enteroendocrine system.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Drug Discovery; Gastric Inhibitory Polypeptide; Glucagon-Like Peptide 1; Glucose; Incretins; Mice; Tyrosine; Zebrafish | 2022 |
Topics: Animals; Bignoniaceae; Blood Glucose; Body Weight; Caspase 3; Diabetes Mellitus, Type 2; Diet, High-Fat; Flowers; Male; Malondialdehyde; Phosphorus; Plant Extracts; Rats; Rats, Sprague-Dawley; Seeds; Streptozocin; Testosterone; Tyrosine | 2022 |
Phosphatase protector alpha4 (α4) is involved in adipocyte maintenance and mitochondrial homeostasis through regulation of insulin signaling.
Topics: Adipocytes; Animals; Diabetes Mellitus, Type 2; Homeostasis; Insulin; Insulin Resistance; Male; Mice; Phosphorylation; Protein Phosphatase 2; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Proto-Oncogene Proteins c-akt; Receptor, Insulin; Serine; Threonine; Tyrosine | 2022 |
Rhamnogalacturonan-I enriched pectin from steamed ginseng ameliorates lipid metabolism in type 2 diabetic rats via gut microbiota and AMPK pathway.
Topics: AMP-Activated Protein Kinases; Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Fatty Acids, Volatile; Gastrointestinal Microbiome; Lipid Metabolism; Panax; Pectins; Rats; Rhamnogalacturonans; RNA, Ribosomal, 16S; Tyrosine | 2023 |
Alterations of morphology and phosphorylated protein expression in the seminal vesicles of diabetic mice.
Topics: Animals; Citric Acid; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Fructosamine; Humans; Infertility, Male; Magnesium; Male; Mice; Mice, Inbred C57BL; Phosphorylation; Seminal Vesicles; Streptozocin; Tyrosine | 2019 |
Palm Fruit Bioactives augment expression of Tyrosine Hydroxylase in the Nile Grass Rat basal ganglia and alter the colonic microbiome.
Topics: Alzheimer Disease; Animals; Basal Ganglia; Brain; Carbohydrates; Catalysis; Colon; Densitometry; Diabetes Mellitus, Type 2; Dietary Carbohydrates; Gastrointestinal Microbiome; Gene Expression Regulation, Enzymologic; Humans; Hydroxylation; Immunohistochemistry; Levodopa; Male; Phoeniceae; Phytochemicals; Rats; Tyrosine; Tyrosine 3-Monooxygenase | 2019 |
Serum Levels of Carbamylated LDL, Nitrotyrosine and Soluble Lectin-like Oxidized Low-density Lipoprotein Receptor-1 in Poorly Controlled Type 2 Diabetes Mellitus.
Topics: Adult; Albuminuria; Biomarkers; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Enzyme-Linked Immunosorbent Assay; Female; Humans; Lipoproteins, LDL; Male; Middle Aged; Scavenger Receptors, Class E; Tyrosine | 2019 |
Plasma phenylalanine and tyrosine and their interactions with diabetic nephropathy for risk of diabetic retinopathy in type 2 diabetes.
Topics: Diabetes Mellitus, Type 2; Diabetic Nephropathies; Diabetic Retinopathy; Humans; Phenylalanine; Tyrosine | 2020 |
Maternal serum nitrotyrosine, 8-isoprostane and total antioxidant capacity levels in pre-gestational or gestational diabetes mellitus.
Topics: Adult; Antioxidants; Case-Control Studies; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetes, Gestational; Dinoprost; Female; Humans; Pre-Eclampsia; Pregnancy; Pregnancy in Diabetics; Pregnancy Outcome; Russia; Tyrosine | 2020 |
Mendelian Randomization Study on Amino Acid Metabolism Suggests Tyrosine as Causal Trait for Type 2 Diabetes.
Topics: Adult; Amino Acids, Aromatic; Amino Acids, Branched-Chain; Case-Control Studies; Diabetes Mellitus, Type 2; Female; Genetic Predisposition to Disease; Genome-Wide Association Study; Glycine; Humans; Male; Mendelian Randomization Analysis; Middle Aged; Prospective Studies; Tyrosine | 2020 |
Effects of clovamide and its related compounds on the aggregations of amyloid polypeptides.
Topics: Amyloid beta-Peptides; Diabetes Mellitus, Type 2; Humans; Structure-Activity Relationship; Tyrosine | 2021 |
Plasma tyrosine and its interaction with low high-density lipoprotein cholesterol and the risk of type 2 diabetes mellitus in Chinese.
Topics: Asian People; Biomarkers; Case-Control Studies; Cholesterol, HDL; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Follow-Up Studies; Humans; Male; Middle Aged; Prognosis; Risk Factors; ROC Curve; Tyrosine | 2019 |
Selective peroxisome proliferator-activated receptor-α modulator K-877 regulates the expression of ATP-binding cassette transporter A1 in pancreatic beta cells.
Topics: Animals; ATP Binding Cassette Transporter 1; Benzoxazoles; Butyrates; Cell Line, Tumor; Diabetes Mellitus, Type 2; Diet, High-Fat; Disease Models, Animal; Dyslipidemias; Glucose; Glucose Intolerance; Humans; Hypolipidemic Agents; Insulin; Insulin-Secreting Cells; Lipid Metabolism; Male; Mice; Mice, Inbred C57BL; Oxazoles; PPAR alpha; Promoter Regions, Genetic; Rats; RNA, Messenger; Tyrosine | 2018 |
The two isoforms of matrix metalloproteinase- 2 have distinct renal spatial and temporal distributions in murine models of types 1 and 2 diabetes mellitus.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Disease Models, Animal; Isoenzymes; Kidney; Kidney Cortex; Kidney Medulla; Kidney Tubules; Male; Matrix Metalloproteinase 2; Mice; Mice, Inbred C57BL; Oxidative Stress; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tyrosine; Up-Regulation | 2018 |
Sitagliptin Protects Cardiac Function by Reducing Nitroxidative Stress and Promoting Autophagy in Zucker Diabetic Fatty (ZDF) Rats.
Topics: Animals; Autophagy; Beclin-1; Blood Glucose; Cell Line; Diabetes Mellitus, Type 2; Diabetic Cardiomyopathies; Dipeptidyl Peptidase 4; Dipeptidyl-Peptidase IV Inhibitors; Disease Models, Animal; Humans; Lipids; Male; Myocytes, Cardiac; Nitrosative Stress; Obesity; Rats, Zucker; Sitagliptin Phosphate; Stroke Volume; Tyrosine; Ventricular Function, Left | 2018 |
Copper ions induce dityrosine-linked dimers in human but not in murine islet amyloid polypeptide (IAPP/amylin).
Topics: Animals; Copper; Diabetes Mellitus, Type 2; Humans; Hydrogen Peroxide; Islet Amyloid Polypeptide; Mice; Protein Aggregation, Pathological; Protein Multimerization; Tyrosine | 2019 |
Protein Tyrosine Phosphatase, Receptor Type B (PTPRB) Inhibits Brown Adipocyte Differentiation through Regulation of VEGFR2 Phosphorylation.
Topics: Adipocytes, Brown; Adipogenesis; Cell Differentiation; Cell Line; Diabetes Mellitus, Type 2; Gene Expression Regulation; Humans; NADH Dehydrogenase; Obesity; Phosphorylation; Receptor-Like Protein Tyrosine Phosphatases, Class 3; Tyrosine; Uncoupling Protein 1; Vascular Endothelial Growth Factor Receptor-2 | 2019 |
Endogenous advanced glycation end products in pancreatic islets after short-term carbohydrate intervention in obese, diabetes-prone mice.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Type 2; Diet, Carbohydrate-Restricted; Diet, High-Fat; Dietary Carbohydrates; Glycation End Products, Advanced; Hyperglycemia; Insulin; Insulin-Secreting Cells; Islets of Langerhans; Mice; Nitric Oxide Synthase Type II; Obesity; Tyrosine | 2019 |
Nine Amino Acids Are Associated With Decreased Insulin Secretion and Elevated Glucose Levels in a 7.4-Year Follow-up Study of 5,181 Finnish Men.
Topics: Aged; Alanine; Amino Acids; Aspartic Acid; Blood Glucose; Diabetes Mellitus, Type 2; Finland; Follow-Up Studies; Glutamic Acid; Humans; Insulin Resistance; Insulin Secretion; Isoleucine; Leucine; Male; Metabolomics; Middle Aged; Phenylalanine; Risk Factors; Tryptophan; Tyrosine; Valine | 2019 |
UP780, a chromone-enriched aloe composition improves insulin sensitivity.
Topics: 3T3-L1 Cells; Adiponectin; Aloe; Animals; Benzophenones; Blood Glucose; Chemistry, Pharmaceutical; Chromones; Diabetes Mellitus, Type 2; Diet, High-Fat; Glucosides; Humans; Insulin; Insulin Resistance; Male; Mice; Mice, Inbred C57BL; Phytotherapy; Plant Preparations; Polysaccharides; Tyrosine | 2013 |
The effect of high-dose insulin analog initiation therapy on lipid peroxidation products and oxidative stress markers in type 2 diabetic patients.
Topics: Adult; Aged; Biomarkers; Blood Glucose; Diabetes Mellitus, Type 2; Dinoprost; Drug Therapy, Combination; Female; Glycated Hemoglobin; Humans; Insulin; Lipid Peroxidation; Male; Metformin; Middle Aged; Nitrates; Nitrites; Oxidative Stress; Protein Carbonylation; Sulfonylurea Compounds; Tyrosine | 2013 |
Characterization of diabetic neuropathy in the Zucker diabetic Sprague-Dawley rat: a new animal model for type 2 diabetes.
Topics: Age Factors; Animals; Arterioles; Blood Glucose; Cholesterol; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Neuropathies; Disease Models, Animal; Fatty Acids, Nonesterified; Fatty Liver; Langerhans Cells; Male; Neural Conduction; Nociception; Rats, Sprague-Dawley; Rats, Zucker; Sciatic Nerve; Time Factors; Triglycerides; Tyrosine; Vasodilation | 2014 |
Association of low GLP-1 with oxidative stress is related to cardiac disease and outcome in patients with type 2 diabetes mellitus: a pilot study.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Aged; Animals; Antioxidants; Atrial Remodeling; Cardiomegaly; Cardiovascular System; Case-Control Studies; Cell Line; Deoxyguanosine; Diabetes Mellitus, Type 2; Dipeptidyl Peptidase 4; Female; Glucagon-Like Peptide 1; Humans; Male; Mice; Middle Aged; Mitochondria; Myocytes, Cardiac; Oxidative Stress; Palmitic Acid; Pilot Projects; Retrospective Studies; Tyrosine; Ventricular Remodeling | 2015 |
An altered pattern of myocardial histopathological and molecular changes underlies the different characteristics of type-1 and type-2 diabetic cardiac dysfunction.
Topics: Animals; Apoptosis; Diabetes Complications; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Fibrosis; Gene Expression Regulation; Heart; Heart Diseases; Hemodynamics; Immunohistochemistry; In Situ Nick-End Labeling; Male; Myocardium; Oxidative Stress; Rats; Rats, Sprague-Dawley; Rats, Zucker; RNA, Messenger; Transforming Growth Factor beta1; Tyrosine; Ventricular Function, Left | 2015 |
[Two catheters for one coronary perforation].
Topics: Aged; Angina, Unstable; Angioplasty, Balloon, Coronary; Antihypertensive Agents; Aspirin; Cardiac Catheterization; Catheters; Combined Modality Therapy; Diabetes Mellitus, Type 2; Dyslipidemias; Femoral Artery; Heart Injuries; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypoglycemic Agents; Male; Percutaneous Coronary Intervention; Premedication; Radial Artery; Stents; Tirofiban; Tyrosine | 2015 |
Troponin in diabetic patients with and without chronic coronary artery disease.
Topics: Aged; Biomarkers; Case-Control Studies; Cholesterol, LDL; Coronary Artery Disease; Diabetes Mellitus, Type 2; Female; Humans; Male; Middle Aged; Natriuretic Peptide, Brain; Oxidation-Reduction; Peroxidase; Risk Factors; Troponin C; Tyrosine | 2015 |
Insulin receptor binding motif tagged with IgG4 Fc (Yiminsu) works as an insulin sensitizer to activate Akt signaling in hepatocytes.
Topics: Animals; Cell Line; CHO Cells; Cloning, Molecular; Cricetulus; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Hepatocytes; Humans; Immunoglobulin Fab Fragments; Immunoglobulin G; Insulin; Insulin Resistance; Phosphatidylinositol 3-Kinase; Phosphorylation; Protein Engineering; Protein Structure, Tertiary; Proto-Oncogene Proteins c-akt; Receptor, Insulin; Receptors, Fc; Recombinant Fusion Proteins; Signal Transduction; Tyrosine | 2015 |
Increased Oxidation as an Additional Mechanism Underlying Reduced Clot Permeability and Impaired Fibrinolysis in Type 2 Diabetes.
Topics: Aged; Aged, 80 and over; Blood Coagulation; Blood Glucose; Diabetes Mellitus, Type 2; Dinoprost; Female; Fibrin; Fibrinolysis; Glomerular Filtration Rate; Glycated Hemoglobin; Glycation End Products, Advanced; Humans; Kinetics; Lipoproteins, LDL; Male; Middle Aged; Oxidative Stress; Oxygen; Permeability; Receptor for Advanced Glycation End Products; Recombinant Proteins; Surveys and Questionnaires; Tissue Plasminogen Activator; Tyrosine | 2015 |
Branched-chain and aromatic amino acid profiles and diabetes risk in Chinese populations.
Topics: Adult; Aged; Amino Acids, Aromatic; Amino Acids, Branched-Chain; China; Chromatography, Liquid; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Humans; Isoleucine; Leucine; Longitudinal Studies; Male; Mass Spectrometry; Middle Aged; Phenylalanine; Risk Factors; Tyrosine; Valine; Young Adult | 2016 |
Association of Plasma DPP4 Activity With Mild Cognitive Impairment in Elderly Patients With Type 2 Diabetes: Results From the GDMD Study in China.
Topics: Aged; Biomarkers; C-Reactive Protein; China; Cognitive Dysfunction; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Dinoprost; Dipeptidyl Peptidase 4; Female; Glycated Hemoglobin; Humans; Inflammation; Interleukin-6; Male; Middle Aged; Odds Ratio; Oxidative Stress; Risk Factors; Tyrosine | 2016 |
Left ventricular pressure-volume measurements and myocardial gene expression profile in type 2 diabetic Goto-Kakizaki rats.
Topics: Animals; Apoptosis; Atrial Natriuretic Factor; Blood Glucose; C-Reactive Protein; Connective Tissue Growth Factor; Diabetes Mellitus, Type 2; Down-Regulation; Echocardiography; Electrocardiography; Fibrosis; Glucose Tolerance Test; Glycosuria; Hypertrophy, Left Ventricular; Immunohistochemistry; In Situ Nick-End Labeling; Inflammation; Interleukin-1beta; Male; Myocardium; Natriuretic Peptide, Brain; Oxidative Stress; Peptide Fragments; Polymerase Chain Reaction; Rats; Rats, Wistar; RNA, Messenger; Signal Transduction; Troponin T; Tumor Necrosis Factor-alpha; Tyrosine; Up-Regulation; Ventricular Dysfunction, Left; Ventricular Function, Left; Ventricular Pressure | 2016 |
Analysis of Chlorination, Nitration, and Nitrosylation of Tyrosine and Oxidation of Methionine and Cysteine in Hemoglobin from Type 2 Diabetes Mellitus Patients by Nanoflow Liquid Chromatography Tandem Mass Spectrometry.
Topics: Adult; Aged; Amino Acid Sequence; Cysteine; Diabetes Mellitus, Type 2; Female; Glycated Hemoglobin; Halogenation; Hemoglobins; Humans; Male; Methionine; Middle Aged; Nitrates; Nitroso Compounds; Oxidation-Reduction; Tyrosine | 2016 |
Tryptophan Predicts the Risk for Future Type 2 Diabetes.
Topics: Adult; Aged; Biomarkers; Blood Glucose; Case-Control Studies; China; Diabetes Mellitus, Type 2; Fasting; Female; Humans; Insulin; Insulin Resistance; Isoleucine; Leucine; Longitudinal Studies; Male; Middle Aged; Phenylalanine; Predictive Value of Tests; Prognosis; Risk Factors; Tryptophan; Tyrosine; Valine | 2016 |
MiR-181c restrains nitration stress of endothelial cells in diabetic db/db mice through inhibiting the expression of FoxO1.
Topics: 3' Untranslated Regions; Animals; Aorta, Thoracic; Blotting, Western; Cell Line; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Endothelial Cells; Endothelium, Vascular; Forkhead Box Protein O1; Gene Expression Regulation; Glucose; Male; Mice, Inbred ICR; MicroRNAs; Nitric Oxide Synthase Type II; Nitrosation; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Tyrosine; Vasodilation | 2017 |
Heightened efficacy of nitric oxide-based therapies in type II diabetes mellitus and metabolic syndrome.
Topics: Animals; Aorta, Abdominal; Apoptosis; Carotid Artery Injuries; Cell Cycle; Cell Proliferation; Cells, Cultured; Diabetes Mellitus, Type 2; Disease Models, Animal; DNA Replication; Dose-Response Relationship, Drug; Hyperplasia; Male; Metabolic Syndrome; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Nitric Oxide; Nitric Oxide Donors; Proline; Rats; Rats, Zucker; Reactive Oxygen Species; S-Nitroso-N-Acetylpenicillamine; Triazenes; Tyrosine | 2008 |
Tyrosine phosphorylation of vitreous inflammatory and angiogenic peptides and proteins in diabetic retinopathy.
Topics: Angiogenesis Inducing Agents; Cytokines; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Eye Proteins; Humans; Immunoblotting; Inflammation Mediators; Male; Middle Aged; Peptides; Phosphorylation; Protein Array Analysis; Tyrosine; Vitrectomy; Vitreous Body | 2009 |
Coagulation and oxidative stress plasmatic levels in a type 2 diabetes population.
Topics: Adult; Biomarkers; Blood Coagulation; Blood Coagulation Factors; Body Mass Index; Diabetes Mellitus, Type 2; Female; Humans; Lipoproteins, LDL; Male; Middle Aged; Oxidative Stress; Tumor Necrosis Factor-alpha; Tyrosine | 2009 |
Possible impact of impaired double-stranded RNA degradation and nitrosative stress on immuno-inflammatory cascade in type 2 diabetes.
Topics: Adult; Aged; Animals; bcl-2-Associated X Protein; Blood Glucose; Cells, Cultured; DEAD-box RNA Helicases; Diabetes Mellitus, Type 2; Female; Fluorescent Antibody Technique; Humans; Inflammation; Interferon Regulatory Factor-3; Interferon-Induced Helicase, IFIH1; Male; Middle Aged; NF-kappa B; Nitrites; Nucleic Acids; Proto-Oncogene Proteins c-bcl-2; Rats; RNA Stability; RNA, Double-Stranded; Thymus Gland; Tyrosine; Xanthine Oxidase | 2009 |
Glycaemic status in relation to oxidative stress and inflammation in well-controlled type 2 diabetes subjects.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Aged; Biomarkers; Blood Glucose; Body Mass Index; C-Reactive Protein; Deoxyguanosine; Diabetes Mellitus, Type 2; Dinoprost; Female; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Inflammation; Insulin; Interleukin-6; Lipids; Male; Malondialdehyde; Middle Aged; Obesity; Oxidative Stress; Probability; Statistics, Nonparametric; Tyrosine; Waist Circumference | 2009 |
Role of MCP-1 in tumor necrosis factor-alpha-induced endothelial dysfunction in type 2 diabetic mice.
Topics: Animals; Arterioles; Biomarkers; Chemokine CCL2; Coronary Vessels; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Female; I-kappa B Proteins; Inflammation Mediators; Macrophages; Male; Mice; Mice, Knockout; NF-kappa B; Nitric Oxide; Oxidative Stress; Peroxynitrous Acid; Phosphorylation; Receptors, Leptin; Serine; Signal Transduction; Superoxides; Tumor Necrosis Factor-alpha; Tyrosine; Vascular Cell Adhesion Molecule-1; Vasodilation; Vasodilator Agents | 2009 |
[Investigation to the levels of 3-nitrotyrosine and their correlation factors in type 2 diabetic patients].
Topics: Aged; Case-Control Studies; Cholesterol, LDL; Diabetes Mellitus, Type 2; Female; Glycated Hemoglobin; Glycated Serum Albumin; Glycation End Products, Advanced; Humans; Male; Middle Aged; Regression Analysis; Serum Albumin; Tyrosine | 2009 |
Silencing mitogen-activated protein 4 kinase 4 (MAP4K4) protects beta cells from tumor necrosis factor-alpha-induced decrease of IRS-2 and inhibition of glucose-stimulated insulin secretion.
Topics: Animals; Cell Death; Cell Proliferation; Cells, Cultured; Diabetes Mellitus, Type 2; Glucose; Humans; Insulin; Insulin Receptor Substrate Proteins; Insulin Secretion; Insulin-Secreting Cells; Intracellular Signaling Peptides and Proteins; Male; Mitogen-Activated Protein Kinases; NF-kappa B; Nitric Oxide Synthase; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-akt; Rats; Rats, Wistar; Signal Transduction; Tumor Necrosis Factor-alpha; Tyrosine | 2009 |
Recovery from hind limb ischemia is less effective in type 2 than in type 1 diabetic mice: roles of endothelial nitric oxide synthase and endothelial progenitor cells.
Topics: Animals; Blood Glucose; Body Weight; Chemotaxis; Collateral Circulation; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Endothelial Cells; Hindlimb; Ischemia; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Muscle, Skeletal; Neovascularization, Physiologic; Nitric Oxide Synthase Type III; Oxidative Stress; Receptors, Leptin; Recovery of Function; Regional Blood Flow; Stem Cells; Time Factors; Tyrosine; Vascular Endothelial Growth Factor A | 2009 |
Hypoglycemic action of chicken meat extract in type-2 diabetic KKAy mice and GK rats.
Topics: Animals; Blood Glucose; Chickens; Diabetes Mellitus, Type 2; Dietary Proteins; Glucose Tolerance Test; Hyperglycemia; Insulin; Insulin Resistance; Male; Meat; Mice; Phosphorylation; Rats; Tyrosine | 2009 |
Formation of methionine sulfoxide by peroxynitrite at position 1606 of von Willebrand factor inhibits its cleavage by ADAMTS-13: A new prothrombotic mechanism in diseases associated with oxidative stress.
Topics: ADAM Proteins; ADAMTS13 Protein; Adult; Binding Sites; Blood Platelets; Case-Control Studies; Diabetes Mellitus, Type 2; Female; Humans; Hydrolysis; Male; Methionine; Middle Aged; Oxidative Stress; Peptide Fragments; Peroxynitrous Acid; Platelet Aggregation; Protein Multimerization; Ristocetin; Tyrosine; von Willebrand Diseases; von Willebrand Factor | 2010 |
Chemical and functional changes of human insulin by in vitro incubation with blood from diabetic patients in oxidative stress.
Topics: Area Under Curve; Biomarkers; Blood Glucose; Diabetes Mellitus, Type 2; Female; Formazans; Humans; Hypoglycemic Agents; Injections, Intraperitoneal; Insulin; Iron; Male; Malondialdehyde; Middle Aged; Oxidation-Reduction; Oxidative Stress; Protein Carbonylation; Reactive Oxygen Species; Tyrosine | 2010 |
Enhancement of insulin responsiveness by nitric oxide-mediated inactivation of protein-tyrosine phosphatases.
Topics: Animals; Chlorocebus aethiops; COS Cells; Cysteine; Diabetes Mellitus, Type 2; Insulin; Insulin Receptor Substrate Proteins; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase Type III; Nitrogen; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatase, Non-Receptor Type 2; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins c-akt; RNA, Small Interfering; Signal Transduction; Transfection; Tyrosine | 2010 |
Enhanced tyrosine nitration of prostacyclin synthase is associated with increased inflammation in atherosclerotic carotid arteries from type 2 diabetic patients.
Topics: Aged; Atherosclerosis; Carotid Arteries; Cytochrome P-450 Enzyme System; Diabetes Mellitus; Diabetes Mellitus, Type 2; Female; Gene Expression Regulation, Enzymologic; Humans; Inflammation; Intramolecular Oxidoreductases; Male; Middle Aged; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxidative Stress; Peroxidase; Tyrosine | 2010 |
Mitochondrial dysfunction in the type 2 diabetic heart is associated with alterations in spatially distinct mitochondrial proteomes.
Topics: Animals; Antioxidants; Cell Respiration; Diabetes Mellitus, Type 2; Disease Models, Animal; Electron Transport; Electron Transport Chain Complex Proteins; Ion Channels; Lipid Peroxidation; Male; Membrane Potential, Mitochondrial; Mice; Mitochondria, Heart; Mitochondrial ADP, ATP Translocases; Mitochondrial Proteins; Mitochondrial Proton-Translocating ATPases; Mitochondrial Size; Oxidative Stress; Protein Processing, Post-Translational; Proteome; Proteomics; Tyrosine; Uncoupling Protein 3 | 2010 |
Increased protein nitration in mitochondrial diseases: evidence for vessel wall involvement.
Topics: Adolescent; Adult; Aged; Base Sequence; Brachial Artery; Case-Control Studies; Deafness; Diabetes Mellitus, Type 2; Endothelium, Vascular; Female; Femoral Artery; Humans; Kearns-Sayre Syndrome; Male; MELAS Syndrome; MERRF Syndrome; Middle Aged; Mitochondrial Diseases; Muscle, Skeletal; Muscle, Smooth, Vascular; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type III; Point Mutation; Sequence Deletion; Tyrosine; Vasodilation | 2011 |
In vivo activation of ROCK1 by insulin is impaired in skeletal muscle of humans with type 2 diabetes.
Topics: Actin Depolymerizing Factors; Adult; Biotransformation; Blotting, Western; Body Mass Index; Cytoskeletal Proteins; Diabetes Mellitus, Type 2; Female; Glucose; Glucose Clamp Technique; Humans; Hypoglycemic Agents; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Kinetics; Male; Middle Aged; Muscle, Skeletal; Obesity; Phosphorylation; rho GTP-Binding Proteins; rho-Associated Kinases; rhoA GTP-Binding Protein; Tyrosine | 2011 |
Hepatic gene expression of the insulin signaling pathway is altered by administration of persimmon peel extract: a DNA microarray study using type 2 diabetic Goto-Kakizaki rats.
Topics: Animals; Cryptoxanthins; Diabetes Mellitus, Type 2; Diospyros; Fruit; Gene Expression; Insulin; Liver; Male; Oligonucleotide Array Sequence Analysis; Phosphorylation; Plant Extracts; Rats; Rats, Wistar; Receptor, Insulin; Signal Transduction; Tyrosine; Xanthophylls | 2011 |
Diabetic Retinopathy Is Associated with Decreased Tyrosine Nitrosylation of Vitreous Interleukins IL-1α, IL-1β, and IL-7.
Topics: Aged; Blood Glucose; Blotting, Western; Chromatography, High Pressure Liquid; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Female; Glycated Hemoglobin; Humans; Immunoprecipitation; Interleukin-1alpha; Interleukin-1beta; Interleukin-7; Male; Middle Aged; Nitric Oxide; Phosphorylation; Phosphotyrosine; Tyrosine; Vitreous Body | 2011 |
Dynamic evaluation of renal resistive index in normoalbuminuric patients with newly diagnosed hypertension or type 2 diabetes.
Topics: Adult; Albuminuria; Blood Glucose; Case-Control Studies; Comorbidity; Diabetes Mellitus, Type 2; Female; Humans; Hypertension; Kidney; Male; Middle Aged; Nitroglycerin; Oxidative Stress; Regional Blood Flow; Tyrosine; Ultrasonography; Vasodilation; Vasodilator Agents | 2011 |
Exercise training improves endothelial function via adiponectin-dependent and independent pathways in type 2 diabetic mice.
Topics: Adiponectin; Analysis of Variance; Animals; Aorta; Diabetes Mellitus, Type 2; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Inflammation Mediators; Interferon-gamma; Male; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Mice, Knockout; NADPH Oxidase 2; NADPH Oxidases; Nitric Oxide; Oxidative Stress; Physical Exertion; Signal Transduction; Superoxide Dismutase; Superoxide Dismutase-1; Superoxides; Time Factors; Tyrosine; Vasodilation; Vasodilator Agents | 2011 |
Distinct cardiac and renal effects of ETA receptor antagonist and ACE inhibitor in experimental type 2 diabetes.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Glucose; Body Weight; Cell Count; Collagen Type III; Diabetes Mellitus, Type 2; Endothelin A Receptor Antagonists; Endothelin-1; Heart; Hemodynamics; Immunohistochemistry; Kidney; Kidney Function Tests; Male; Muscle Cells; Myocardium; Rats; Rats, Zucker; Real-Time Polymerase Chain Reaction; Receptors, Vascular Endothelial Growth Factor; Survival; Tyrosine; Vascular Endothelial Growth Factor A | 2011 |
Effects of glutamine supplementation on oxidative stress-related gene expression and antioxidant properties in rats with streptozotocin-induced type 2 diabetes.
Topics: Animals; Antioxidants; Base Sequence; Carrier Proteins; Cell Cycle Proteins; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dietary Supplements; DNA Primers; Erythrocytes; Gene Expression; Glutamine; Glutathione; Kidney; Male; Oxidative Stress; Rats; Rats, Wistar; RNA, Messenger; Tyrosine | 2012 |
Exacerbation of endothelial dysfunction during the progression of diabetes: role of oxidative stress.
Topics: Animals; Diabetes Mellitus, Type 2; Disease Models, Animal; Disease Progression; Endothelium, Vascular; Hyperglycemia; Hyperinsulinism; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxidative Stress; Superoxides; Time Factors; Tyrosine | 2012 |
Postchallenge responses of nitrotyrosine and TNF-alpha during 75-g oral glucose tolerance test are associated with the presence of coronary artery diseases in patients with prediabetes.
Topics: Aged; Biomarkers; Blood Glucose; Coronary Angiography; Coronary Artery Disease; Diabetes Complications; Diabetes Mellitus, Type 2; Female; Glucose Tolerance Test; Humans; Inflammation Mediators; Interleukin-6; Logistic Models; Male; Middle Aged; Odds Ratio; Prediabetic State; Risk Assessment; Risk Factors; Taiwan; Time Factors; Tumor Necrosis Factor-alpha; Tyrosine | 2012 |
Evidence for a role of frataxin in pancreatic islets isolated from multi-organ donors with and without type 2 diabetes mellitus.
Topics: Diabetes Mellitus, Type 2; Female; Frataxin; Gene Expression Regulation; Humans; Iron-Binding Proteins; Islets of Langerhans; Male; Middle Aged; Regression Analysis; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; Tissue Donors; Tyrosine | 2012 |
Cerebral myogenic reactivity and blood flow in type 2 diabetic rats: role of peroxynitrite in hypoxia-mediated loss of myogenic tone.
Topics: Actins; Animals; Cell Hypoxia; Cerebrovascular Circulation; Diabetes Mellitus, Type 2; Disease Models, Animal; Hyperemia; Male; Metalloporphyrins; Middle Cerebral Artery; Muscle, Smooth, Vascular; Peroxynitrous Acid; Rats; Rats, Wistar; Tyrosine | 2012 |
Design novel dual agonists for treating type-2 diabetes by targeting peroxisome proliferator-activated receptors with core hopping approach.
Topics: Binding Sites; Diabetes Mellitus, Type 2; Drug Design; Humans; Hypoglycemic Agents; Ligands; Models, Molecular; Molecular Conformation; Molecular Dynamics Simulation; Molecular Structure; Oxazoles; PPAR alpha; PPAR gamma; Protein Structure, Tertiary; Tyrosine | 2012 |
Obstructive sleep apnea and diabetic neuropathy: a novel association in patients with type 2 diabetes.
Topics: Adult; Aged; Biomarkers; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Female; Humans; Linear Models; Lipid Peroxides; Male; Microcirculation; Middle Aged; Multivariate Analysis; Oxidative Stress; Prevalence; Severity of Illness Index; Skin; Sleep Apnea, Obstructive; Tyrosine | 2012 |
Metanx alleviates multiple manifestations of peripheral neuropathy and increases intraepidermal nerve fiber density in Zucker diabetic fatty rats.
Topics: Animals; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Disease Models, Animal; Folic Acid; Hyperalgesia; Male; Nerve Fibers; Neural Conduction; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Pyridoxal Phosphate; Rats; Rats, Zucker; Sciatic Nerve; Tibial Nerve; Tyrosine; Vitamin B 12 | 2012 |
Increased cellular and circulating biomarkers of oxidative stress in nascent metabolic syndrome.
Topics: Adult; Biomarkers; Body Mass Index; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Female; Humans; Lipoproteins, LDL; Male; Metabolic Syndrome; Middle Aged; Monocytes; NADPH Oxidases; NF-E2 Transcription Factor; Oxidative Stress; Prevalence; Risk Factors; Superoxides; Tyrosine | 2012 |
Iron increases liver injury through oxidative/nitrative stress in diabetic rats: Involvement of nitrotyrosination of glucokinase.
Topics: Animals; Blotting, Western; Body Weight; Diabetes Mellitus, Type 2; Glucokinase; Iron; Iron Overload; Liver; Liver Function Tests; Male; Nitrates; Nitric Oxide; Nitrites; Organ Size; Oxidation-Reduction; Oxidative Stress; Random Allocation; Rats; Rats, Wistar; Streptozocin; Tandem Mass Spectrometry; Tyrosine | 2012 |
Anti-diabetic atherosclerosis effect of Prunella vulgaris in db/db mice with type 2 diabetes.
Topics: Acetylcholine; Animals; Aorta; Atherosclerosis; Blood Glucose; Blood Pressure; Blood Urea Nitrogen; Cholesterol, Dietary; Creatinine; Diabetes Complications; Diabetes Mellitus, Type 2; Diet, High-Fat; Dose-Response Relationship, Drug; Endothelin-1; Hyperglycemia; Hypertrophy; Hypoglycemic Agents; Intercellular Adhesion Molecule-1; Lipids; Male; Malondialdehyde; Mice; Mice, Inbred Strains; Mice, Knockout; Nitric Oxide; Phytotherapy; Plant Extracts; Prunella; Transforming Growth Factor beta1; Tunica Intima; Tunica Media; Tyrosine; Vascular Cell Adhesion Molecule-1; Vasodilation | 2012 |
Sitagliptin: anti-platelet effect in diabetes and healthy volunteers.
Topics: Adult; Aged; Blood Platelets; Blood Proteins; Calcium; Case-Control Studies; Cells, Cultured; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Hypoglycemic Agents; Male; Middle Aged; Phosphorylation; Platelet Activation; Platelet Aggregation; Platelet Aggregation Inhibitors; Pyrazines; Sitagliptin Phosphate; Thrombin; Triazoles; Tyrosine | 2012 |
Changes in microvascular reactivity after cardiopulmonary bypass in patients with poorly controlled versus controlled diabetes.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Diphosphate; Aged; Arterioles; Cardiopulmonary Bypass; Coronary Artery Bypass; Cyclic AMP-Dependent Protein Kinases; Diabetes Mellitus, Type 2; Disease Susceptibility; Endothelium, Vascular; Enzyme Induction; Female; Gene Expression Regulation; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Inflammation; Male; Microcirculation; Middle Aged; Muscle, Skeletal; Nitroprusside; Phosphorylation; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-akt; Substance P; Tyrosine; Vasoconstriction; Vasodilator Agents | 2012 |
Decreased glycolytic and tricarboxylic acid cycle intermediates coincide with peripheral nervous system oxidative stress in a murine model of type 2 diabetes.
Topics: Aconitate Hydratase; Animals; Citric Acid Cycle; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Disease Models, Animal; Down-Regulation; Ganglia, Spinal; Glycolysis; Lipid Peroxidation; Male; Mice; Mice, Mutant Strains; Neurons; Oxidative Stress; Peripheral Nervous System; Receptors, Leptin; Sciatic Nerve; Sural Nerve; Tyrosine | 2013 |
The importance of L-arginine metabolism modulation in diabetic patients with distal symmetric polyneuropathy.
Topics: Aged; Arginase; Arginine; Blood Glucose; Chromatography, High Pressure Liquid; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Electrodiagnosis; Female; Fructosamine; Glycated Hemoglobin; Humans; Male; Methylation; Middle Aged; Nitrates; Nitrites; S-Nitrosothiols; Tyrosine | 2013 |
Role of aromatic interactions in amyloid formation by islet amyloid polypeptide.
Topics: Amino Acid Sequence; Amino Acid Substitution; Diabetes Mellitus, Type 2; Humans; Islet Amyloid Polypeptide; Kinetics; Leucine; Models, Molecular; Molecular Sequence Data; Phenylalanine; Propanols; Tyrosine | 2013 |
Phosphorylation of myocardial eNOS is altered in patients suffering from type 2 diabetes.
Topics: Adult; Aged; Aged, 80 and over; Angiotensin II; Diabetes Mellitus, Type 2; Dinoprost; Humans; Middle Aged; Myocardium; Nitric Oxide Synthase Type III; Oxidative Stress; Phosphorylation; Proto-Oncogene Proteins c-akt; Tyrosine | 2013 |
Role of hyperglycemia in nitrotyrosine postprandial generation.
Topics: Biomarkers; Blood Glucose; Diabetes Mellitus, Type 2; Female; Humans; Hyperglycemia; Male; Middle Aged; Oxidative Stress; Postprandial Period; Triglycerides; Tyrosine | 2002 |
Structural and biochemical evidence for an autoinhibitory role for tyrosine 984 in the juxtamembrane region of the insulin receptor.
Topics: Amino Acid Sequence; Animals; Binding Sites; Cell Membrane; Crystallography, X-Ray; Diabetes Mellitus, Type 2; Humans; Kinetics; Models, Molecular; Molecular Sequence Data; Phosphorylation; Protein Binding; Protein Structure, Tertiary; Receptor, Insulin; Transfection; Tyrosine | 2003 |
Insulin-stimulated protein kinase C lambda/zeta activity is reduced in skeletal muscle of humans with obesity and type 2 diabetes: reversal with weight reduction.
Topics: 3-Phosphoinositide-Dependent Protein Kinases; Adult; Diabetes Mellitus; Diabetes Mellitus, Type 2; Diet; Energy Intake; Female; Humans; Insulin Receptor Substrate Proteins; Isoenzymes; Male; Middle Aged; Muscle, Skeletal; Obesity; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Protein Kinase C; Protein Kinase C-alpha; Protein Kinase C-epsilon; Protein Kinase C-theta; Protein Serine-Threonine Kinases; Receptor, Insulin; Tyrosine; Weight Loss | 2003 |
Impaired IRS-1/PI3-kinase signaling in patients with HCV: a mechanism for increased prevalence of type 2 diabetes.
Topics: Adult; Diabetes Mellitus, Type 2; Female; Hepatitis C; Humans; Insulin; Insulin Receptor Substrate Proteins; Male; Middle Aged; Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Prevalence; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Signal Transduction; Tyrosine | 2003 |
Metabolic stability, receptor binding, cAMP generation, insulin secretion and antihyperglycaemic activity of novel N-terminal Glu9-substituted analogues of glucagon-like peptide-1.
Topics: Adenosine Deaminase; Amino Acid Substitution; Animals; Binding, Competitive; Blood Glucose; Cell Line, Tumor; Cricetinae; Cyclic AMP; Diabetes Mellitus, Type 2; Dipeptidyl Peptidase 4; Fibroblasts; Glucagon; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Glucose; Glutamine; Glycoproteins; Humans; Hypoglycemic Agents; Insulin; Insulin Secretion; Islets of Langerhans; Mice; Mice, Obese; Peptide Fragments; Phenylalanine; Proline; Protein Precursors; Rats; Receptors, Glucagon; Spectrometry, Mass, Electrospray Ionization; Transformation, Genetic; Tyrosine | 2003 |
The 16189 variant of mitochondrial DNA occurs more frequently in C282Y homozygotes with haemochromatosis than those without iron loading.
Topics: Adult; Aged; Aged, 80 and over; Amino Acid Substitution; Cohort Studies; Cysteine; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; DNA, Mitochondrial; Gene Frequency; Genotype; Hemochromatosis; Hemochromatosis Protein; Histocompatibility Antigens Class I; Homozygote; Humans; Iron Overload; Membrane Proteins; Middle Aged; Mutation; Phenotype; Tyrosine | 2004 |
Hepatitis C virus infection and diabetes: direct involvement of the virus in the development of insulin resistance.
Topics: Animals; Antibodies; Blood Glucose; Diabetes Mellitus, Type 2; Dietary Fats; Glucose Clamp Technique; Hepacivirus; Hepatitis C; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Islets of Langerhans; Liver; Male; Mice; Mice, Transgenic; Phosphoproteins; Phosphorylation; Tumor Necrosis Factor-alpha; Tyrosine; Viral Core Proteins | 2004 |
Inducible nitric oxide synthase and vascular endothelial growth factor are colocalized in the retinas of human subjects with diabetes.
Topics: Adult; Aged; Diabetes Mellitus, Type 2; Female; Glial Fibrillary Acidic Protein; Humans; Male; Middle Aged; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Prospective Studies; Retina; Tyrosine; Vascular Endothelial Growth Factors | 2004 |
Insulin receptor substrate-2-dependent interleukin-4 signaling in macrophages is impaired in two models of type 2 diabetes mellitus.
Topics: Amino Acid Motifs; Animals; Blood Glucose; Blotting, Western; Cell Line; Diabetes Mellitus, Type 2; Glucose; Heterozygote; Humans; Insulin; Insulin Receptor Substrate Proteins; Interleukin-4; Intracellular Signaling Peptides and Proteins; Macrophages; Macrophages, Peritoneal; Mice; Mice, Inbred C57BL; Mice, Transgenic; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Serine; Signal Transduction; Sirolimus; Tetradecanoylphorbol Acetate; Time Factors; Tyrosine; U937 Cells | 2004 |
[Study on the association of PPP1R3 gene polymorphism with type 2 diabetes in Han population of Anhui province].
Topics: Adult; Alleles; Aspartic Acid; China; Diabetes Mellitus, Type 2; Female; Gene Frequency; Genotype; Humans; Male; Middle Aged; Obesity; Phosphoprotein Phosphatases; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Protein Phosphatase 1; Risk Factors; Tyrosine | 2004 |
Expression of angiogenic factors during acute coronary syndromes in human type 2 diabetes.
Topics: Acute Disease; Angina, Unstable; Collateral Circulation; Coronary Artery Bypass; Diabetes Mellitus, Type 2; Female; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Male; Middle Aged; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; RNA, Messenger; Superoxides; Transcription Factors; Tyrosine; Vascular Endothelial Growth Factor A; Ventricular Function | 2004 |
Inhibition of islet amyloid polypeptide fibril formation: a potential role for heteroaromatic interactions.
Topics: Amino Acid Substitution; Amyloid; Animals; Cell Line; Cell Survival; Diabetes Mellitus, Type 2; Flavonoids; Growth Inhibitors; Humans; Islet Amyloid Polypeptide; Islets of Langerhans; Mice; PC12 Cells; Peptide Fragments; Phenols; Phenolsulfonphthalein; Phenylalanine; Polyphenols; Protein Binding; Protein Interaction Mapping; Rats; Spectrometry, Fluorescence; Tyrosine | 2004 |
Impaired arachidonic acid-mediated dilation of small mesenteric arteries in Zucker diabetic fatty rats.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Animals; Arachidonate 12-Lipoxygenase; Arachidonic Acid; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Eicosanoids; Male; Mesenteric Arteries; Nitrogen; Obesity; Potassium Channels; Rats; Rats, Zucker; RNA, Messenger; Tyrosine; Vasodilation | 2005 |
Functional and molecular defects of pancreatic islets in human type 2 diabetes.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Adult; Aged; AMP-Activated Protein Kinases; Deoxyguanosine; Diabetes Mellitus, Type 2; Female; Gene Expression; Glucose; Glutathione; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Male; Middle Aged; Multienzyme Complexes; Oxidative Stress; Protein Serine-Threonine Kinases; Time Factors; Tyrosine | 2005 |
Nitric oxide dynamics and endothelial dysfunction in type II model of genetic diabetes.
Topics: Animals; Aorta, Thoracic; Biopterins; Body Weight; Diabetes Mellitus, Type 2; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Female; Humans; In Vitro Techniques; Isoprostanes; Male; NADPH Oxidases; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitroprusside; Oxidation-Reduction; Protein Subunits; Proteins; Rats; Rats, Inbred Strains; Rats, Wistar; Superoxide Dismutase; Superoxides; Tyrosine; Vasodilation; Vasodilator Agents | 2005 |
Activation of PPARgamma enhances myocardial glucose oxidation and improves contractile function in isolated working hearts of ZDF rats.
Topics: Adaptation, Physiological; Animals; Diabetes Mellitus, Type 2; Disease Models, Animal; Energy Metabolism; Gene Expression Regulation; Glucose; In Vitro Techniques; Insulin Resistance; Male; Myocardial Contraction; Myocardium; Oxazoles; PPAR gamma; Rats; Rats, Inbred Strains; Rats, Zucker; Signal Transduction; Transcriptional Activation; Triglycerides; Tyrosine | 2005 |
Adiponectin polymorphisms, adiposity and insulin metabolism: HERITAGE family study and Oulu diabetic study.
Topics: Adipocytes; Adiponectin; Adipose Tissue; Black People; Case-Control Studies; Diabetes Mellitus, Type 2; Female; Finland; Gene Frequency; Haplotypes; Histidine; Humans; Insulin; Intercellular Signaling Peptides and Proteins; Male; Middle Aged; Polymorphism, Genetic; Risk Factors; Tyrosine; White People | 2005 |
Attenuation of insulin-stimulated insulin receptor substrate-1 serine 307 phosphorylation in insulin resistance of type 2 diabetes.
Topics: Adipocytes; Aged; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Electrophoresis, Gel, Two-Dimensional; Electrophoresis, Polyacrylamide Gel; Female; Humans; Immunoblotting; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Kinetics; Male; Middle Aged; Okadaic Acid; Phosphoproteins; Phosphorylation; Serine; Signal Transduction; Sirolimus; Time Factors; Tyrosine | 2005 |
Increased collagen content in insulin-resistant skeletal muscle.
Topics: Adult; Biopsy; Collagen Type I; Collagen Type III; Diabetes Mellitus, Type 2; Extracellular Matrix; Female; Glucose; Humans; Hydroxyproline; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Male; Microscopy, Fluorescence; Middle Aged; Muscle, Skeletal; Obesity; Phosphoproteins; Phosphorylation; Tyrosine | 2006 |
Accumulation of the hydroxyl free radical markers meta-, ortho-tyrosine and DOPA in cataractous lenses is accompanied by a lower protein and phenylalanine content of the water-soluble phase.
Topics: Aged; Cataract; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Dihydroxyphenylalanine; Eye Proteins; Humans; Hydroxyl Radical; Lens, Crystalline; Middle Aged; Phenylalanine; Solubility; Tyrosine; Water | 2005 |
Effects of escalating doses of tirofiban on platelet aggregation and major receptor expression in diabetic patients: hitting the TARGET in the TENACITY trial?
Topics: Aged; Blood Platelets; Cells, Cultured; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Dose-Response Relationship, Drug; Female; Flow Cytometry; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Glycoprotein GPIIb-IIIa Complex; Receptors, Cell Surface; Tirofiban; Tyrosine | 2007 |
The vascular smooth muscle cells apoptosis in asymptomatic diabetic carotid plaques: role of glycemic control.
Topics: Actins; Aged; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Apoptosis; Blood Glucose; Carotid Stenosis; Caspase 3; Caspases; Collagen; Diabetes Mellitus, Type 2; Endarterectomy, Carotid; Female; Glycated Hemoglobin; Humans; Hyperglycemia; In Situ Nick-End Labeling; Interleukin-1; Macrophages; Male; Muscle, Smooth, Vascular; Oxidative Stress; Tumor Necrosis Factor-alpha; Tyrosine | 2006 |
eNOS gene therapy exacerbates hepatic ischemia-reperfusion injury in diabetes: a role for eNOS uncoupling.
Topics: Animals; Biological Availability; Biopterins; Diabetes Mellitus, Type 2; Drug Synergism; Genetic Therapy; Liver; Metalloporphyrins; Mice; Mice, Inbred Strains; Mice, Transgenic; Nitric Oxide Donors; Nitric Oxide Synthase Type III; Nitrites; Phenotype; Phosphorylation; Pterins; Reperfusion Injury; Severity of Illness Index; Tyrosine | 2006 |
Calorie restriction improves cardiovascular risk factors via reduction of mitochondrial reactive oxygen species in type II diabetic rats.
Topics: Animals; Body Weight; Caloric Restriction; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Glucose Transporter Type 4; Ion Channels; Lipid Peroxidation; Male; Mitochondria; Mitochondrial Proteins; Nitric Oxide Synthase Type III; Organ Size; Plasminogen Activator Inhibitor 1; Rats; Rats, Long-Evans; Reactive Oxygen Species; Risk Factors; Tyrosine; Uncoupling Protein 2 | 2007 |
Effects of eicosapentaenoic acid on the early stage of type 2 diabetic nephropathy in KKA(y)/Ta mice: involvement of anti-inflammation and antioxidative stress.
Topics: Animals; Anti-Inflammatory Agents; Chemokine CCL2; Collagen Type I; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Eicosapentaenoic Acid; Lipid Peroxidation; Macrophages; Male; Mice; Oxidative Stress; Phenotype; Transforming Growth Factor beta1; Tyrosine | 2006 |
Effect of pyridoxamine (K-163), an inhibitor of advanced glycation end products, on type 2 diabetic nephropathy in KK-A(y)/Ta mice.
Topics: Animals; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Dose-Response Relationship, Drug; Glycation End Products, Advanced; Immunohistochemistry; Laminin; Lysine; Male; Mice; Pyridoxamine; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Schiff Bases; Transforming Growth Factor beta1; Tyrosine | 2007 |
Plasma concentrations of myeloperoxidase predict mortality after myocardial infarction.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Biomarkers; Case-Control Studies; Diabetes Mellitus, Type 2; Female; Follow-Up Studies; Humans; Male; Middle Aged; Myocardial Infarction; Neurotransmitter Agents; New Zealand; Peroxidase; Prognosis; Proportional Hazards Models; Protein Carbonylation; Radionuclide Imaging; Retrospective Studies; Sex Factors; Stroke Volume; Tyrosine; Ventricular Dysfunction, Left | 2007 |
Insulin secretion defects of human type 2 diabetic islets are corrected in vitro by a new reactive oxygen species scavenger.
Topics: Antioxidants; Cells, Cultured; Diabetes Mellitus, Type 2; Glucose; Humans; Insulin; Insulin Secretion; Islets of Langerhans; Oxidative Stress; Reactive Oxygen Species; Tyrosine | 2007 |
Reduction of oxidative stress by a new low-molecular-weight antioxidant improves metabolic alterations in a nonobese mouse diabetes model.
Topics: Animals; Antioxidants; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Esters; Fatty Acids, Nonesterified; Glucose Intolerance; Glucose Tolerance Test; Hyperglycemia; Hypoglycemic Agents; Insulin; Male; Mice; Mice, Inbred C57BL; Molecular Weight; Niacinamide; Oxidative Stress; Pancreas; Piperidines; Streptozocin; Time Factors; Tyrosine | 2007 |
Renal mitochondrial damage and protein modification in type-2 diabetes.
Topics: Animals; Cytosol; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Male; Mice; Mice, Inbred C57BL; Microcirculation; Mitochondria; Mitochondrial Membranes; Oxidation-Reduction; Oxidative Stress; Permeability; Reference Values; Tyrosine | 2008 |
Effect of pitavastatin on type 2 diabetes mellitus nephropathy in KK-Ay/Ta mice.
Topics: Animals; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Glycated Hemoglobin; GTP Cyclohydrolase; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunohistochemistry; Mice; Mice, Inbred C57BL; NADPH Oxidases; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Protein Kinase C; Quinolines; RNA, Messenger; Tyrosine | 2008 |
Dietary advanced glycation endproducts and oxidative stress: in vivo effects on endothelial function and adipokines.
Topics: Adipokines; Adiponectin; Adult; Age of Onset; Aged; Diabetes Mellitus, Type 2; Diet; E-Selectin; Endothelium, Vascular; Female; Glycation End Products, Advanced; Humans; Inpatients; Leptin; Male; Middle Aged; Oxidative Stress; Thiobarbituric Acid Reactive Substances; Tyrosine | 2008 |
Reduced tyrosine kinase activity of the insulin receptor in obesity-diabetes. Central role of tumor necrosis factor-alpha.
Topics: Adipose Tissue; Animals; Diabetes Mellitus; Diabetes Mellitus, Type 2; Disease Models, Animal; Immunoglobulin G; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Liver; Male; Muscles; Neutralization Tests; Obesity; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Rats; Rats, Zucker; Receptor, Insulin; Receptors, Tumor Necrosis Factor; Recombinant Fusion Proteins; Specific Pathogen-Free Organisms; Tumor Necrosis Factor-alpha; Tyrosine | 1994 |
Frequency of mutations of insulin receptor gene in Japanese patients with NIDDM.
Topics: Adult; Aged; Alanine; Amino Acid Sequence; Animals; Base Sequence; Cell Line; Chlorocebus aethiops; Cysteine; Diabetes Mellitus, Type 2; DNA; DNA Primers; Exons; Female; Genetic Linkage; Humans; Insulin; Japan; Kinetics; Macromolecular Substances; Male; Middle Aged; Molecular Sequence Data; Pedigree; Phosphatidylinositol 3-Kinases; Phosphotransferases (Alcohol Group Acceptor); Point Mutation; Polymerase Chain Reaction; Receptor, Insulin; Recombinant Proteins; Threonine; Transfection; Tyrosine | 1995 |
Solid versus liquid phase assays in detection of insulin antibodies. Influence of iodination site on labelled insulin binding.
Topics: Adolescent; Adult; Aged; Autoantibodies; Binding Sites, Antibody; Child; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Enzyme-Linked Immunosorbent Assay; Female; Humans; Insulin; Insulin Antibodies; Iodine Radioisotopes; Male; Middle Aged; Radioligand Assay; Tyrosine | 1994 |
Peroxovanadate and insulin action in adipocytes from NIDDM patients. Evidence against a primary defect in tyrosine phosphorylation.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adipocytes; Adrenergic beta-Agonists; Adult; Animals; Blood Glucose; Case-Control Studies; Diabetes Mellitus, Type 2; Dose-Response Relationship, Drug; Humans; Hypoglycemic Agents; Insulin; Isoproterenol; Lipolysis; Male; Mice; Middle Aged; Phosphorylation; Receptor, Insulin; Tyrosine; Vanadates | 1997 |
Expression of variant forms of insulin receptor substrate-1 identified in patients with noninsulin-dependent diabetes mellitus.
Topics: Adaptor Proteins, Signal Transducing; Cell Line; Diabetes Mellitus, Type 2; Genetic Variation; GRB2 Adaptor Protein; Humans; Insulin; Insulin Receptor Substrate Proteins; Mutation; Peptide Fragments; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Proteins; Tyrosine | 1997 |
Asp905Tyr polymorphism of the gene for the skeletal muscle-specific glycogen-targeting subunit of protein phosphatase 1 in NIDDM.
Topics: Adult; Aged; Alleles; Amino Acid Substitution; Aspartic Acid; Body Mass Index; Data Interpretation, Statistical; Diabetes Mellitus, Type 2; Female; Gene Frequency; Genes; Genotype; Glycogen; Humans; Hypoglycemic Agents; Insulin; Male; Middle Aged; Muscle, Skeletal; Phosphoprotein Phosphatases; Polymorphism, Genetic; Protein Phosphatase 1; Tyrosine | 1998 |
C282Y mutation in HFE (haemochromatosis) gene and type 2 diabetes.
Topics: Adult; Codon; Cysteine; Diabetes Mellitus, Type 2; England; Female; Genetic Predisposition to Disease; Genetic Testing; Hemochromatosis; Humans; Male; Middle Aged; Mutation; Polymerase Chain Reaction; Prevalence; Tyrosine | 1998 |
Mutations in HFE, the hemochromatosis candidate gene, in patients with NIDDM.
Topics: Amino Acid Substitution; Aspartic Acid; Cysteine; Diabetes Mellitus, Type 2; Hemochromatosis; Hemochromatosis Protein; Histidine; Histocompatibility Antigens Class I; HLA Antigens; Homozygote; Humans; Major Histocompatibility Complex; Membrane Proteins; Point Mutation; Reference Values; Tyrosine | 1998 |
Glycoxidation, and protein and DNA oxidation in patients with diabetes mellitus.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Aged; Arginine; Biomarkers; Case-Control Studies; Chromatography, High Pressure Liquid; Deoxyguanosine; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Humans; Lysine; Middle Aged; Oxidative Stress; Statistics, Nonparametric; Tyrosine | 1998 |
Patients with type 2 diabetes have a high frequency of the C282Y mutation of the hemochromatosis gene.
Topics: Adolescent; Adult; Cysteine; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Female; Hemochromatosis; Humans; Male; Middle Aged; Point Mutation; Tyrosine | 1998 |
Novel allele of the insulin receptor substrate-1 bearing two non-conservative amino acid substitutions in a patient with noninsulin-dependent diabetes mellitus. Mutations in brief no. 130. Online.
Topics: Alleles; Amino Acid Substitution; Diabetes Mellitus, Type 2; Humans; Insulin Receptor Substrate Proteins; Phosphoproteins; Receptor, Insulin; Serine; Tyrosine | 1998 |
Clinical characteristics of type 2 diabetes in patients with mutations of HFE.
Topics: Amino Acid Substitution; Aspartic Acid; Cysteine; Diabetes Mellitus, Type 2; Female; Ferritins; Hemochromatosis Protein; Heterozygote; Histidine; Histocompatibility Antigens Class I; HLA Antigens; Humans; Insulin Resistance; Iron; Major Histocompatibility Complex; Male; Membrane Proteins; Middle Aged; Point Mutation; Transferrin; Tyrosine | 2000 |
Characterization of signal transduction and glucose transport in skeletal muscle from type 2 diabetic patients.
Topics: Biological Transport; Diabetes Mellitus, Type 2; Glucose; Glycogen Synthase; Humans; Insulin; Insulin Receptor Substrate Proteins; Male; Middle Aged; Mitogen-Activated Protein Kinases; Muscle, Skeletal; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Phosphotyrosine; Receptor, Insulin; Signal Transduction; Time Factors; Tyrosine | 2000 |
Myocardial cell death in human diabetes.
Topics: Angiotensin II; Apoptosis; Cardiomegaly; Diabetes Mellitus, Type 2; Female; Heart Failure; Humans; Hypertension; Male; Middle Aged; Oxidative Stress; Reactive Oxygen Species; Renin-Angiotensin System; Tyrosine | 2000 |
Diabetes in the Goto-Kakizaki rat is accompanied by impaired insulin-mediated myosin-bound phosphatase activation and vascular smooth muscle cell relaxation.
Topics: Animals; Cells, Cultured; Diabetes Mellitus, Type 2; Enzyme Activation; Insulin; Insulin Receptor Substrate Proteins; Isoenzymes; Muscle, Smooth, Vascular; Myosin-Light-Chain Phosphatase; Nitric Oxide Synthase; Phosphatidylinositol 3-Kinases; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation; Precipitin Tests; Protein Serine-Threonine Kinases; Rats; Rats, Inbred Strains; Receptor, Insulin; Reference Values; Signal Transduction; Tyrosine; Vasodilation | 2000 |
Non-thiazolidinedione insulin sensitiser shows promise.
Topics: Clinical Trials, Phase III as Topic; Diabetes Mellitus, Type 2; Drug Industry; Humans; Hypoglycemic Agents; Multicenter Studies as Topic; Oxazoles; Thiazoles; Tyrosine | 2000 |
Oxidative stress and nitric oxide related parameters in type II diabetes mellitus: effects of glycemic control.
Topics: Adult; Aged; Case-Control Studies; Catalase; Cyclic GMP; Diabetes Mellitus, Type 2; Erythrocytes; Female; Glutathione Peroxidase; Humans; Hyperglycemia; Hypoglycemic Agents; Male; Middle Aged; Nitrates; Nitric Oxide; Nitrites; Oxidative Stress; Reactive Oxygen Species; Selenium; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances; Time Factors; Tyrosine | 2001 |
Islet amyloid polypeptide: identification of long-range contacts and local order on the fibrillogenesis pathway.
Topics: Amino Acid Sequence; Amyloid; Amyloidosis; Animals; Diabetes Mellitus, Type 2; Energy Transfer; Fluorescence Polarization; Fluorescent Dyes; Humans; Hydrogen-Ion Concentration; Islet Amyloid Polypeptide; Kinetics; Light; Molecular Sequence Data; Osmolar Concentration; Protein Denaturation; Protein Structure, Quaternary; Rats; Rotation; Scattering, Radiation; Sequence Alignment; Solvents; Static Electricity; Titrimetry; Tyrosine | 2001 |
Activation of renal signaling pathways in db/db mice with type 2 diabetes.
Topics: Animals; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Hyperinsulinism; Kidney Cortex; Liver; MAP Kinase Signaling System; Mice; Mice, Mutant Strains; Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Receptor, Insulin; Tyrosine | 2001 |
Detection of nitrotyrosine in the diabetic plasma: evidence of oxidative stress.
Topics: Antioxidants; Biomarkers; Blood Glucose; Diabetes Mellitus, Type 2; Enzyme-Linked Immunosorbent Assay; Female; Humans; Male; Middle Aged; Oxidative Stress; Reference Values; Sensitivity and Specificity; Tyrosine | 2001 |
Skeletal muscle insulin resistance in normoglycemic subjects with a strong family history of type 2 diabetes is associated with decreased insulin-stimulated insulin receptor substrate-1 tyrosine phosphorylation.
Topics: Adult; Diabetes Mellitus, Type 2; Female; Glucose Clamp Technique; Glucose Tolerance Test; Humans; Insulin; Insulin Receptor Substrate Proteins; Insulin Resistance; Male; Medical Records; Muscle, Skeletal; Phosphoproteins; Phosphorylation; Receptor, Insulin; Signal Transduction; Tyrosine | 2001 |
Changes in membrane microenvironment and signal transduction in platelets from NIDDM patients-a pilot study.
Topics: Adult; Blood Platelets; Calcimycin; Calpain; Case-Control Studies; Cell Membrane; Diabetes Mellitus, Type 2; Epinephrine; Humans; Middle Aged; Phosphorylation; Pilot Projects; Platelet Activation; Platelet Aggregation; Reference Values; Signal Transduction; Tyrosine | 2002 |
Vanadate normalizes hyperglycemia in two mouse models of non-insulin-dependent diabetes mellitus.
Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Type 2; Insulin; Liver; Mice; Mice, Mutant Strains; Mice, Obese; Microscopy, Electron; Phosphoprotein Phosphatases; Phosphotyrosine; Protein Tyrosine Phosphatases; Tyrosine; Vanadium | 1991 |
Mechanism of defective insulin-receptor kinase activity in NIDDM. Evidence for two receptor populations.
Topics: Adipose Tissue; Adult; Aged; Diabetes Mellitus; Diabetes Mellitus, Type 2; Humans; Insulin; Middle Aged; Obesity; Phosphorylation; Phosphotyrosine; Precipitin Tests; Protein-Tyrosine Kinases; Receptor, Insulin; Tyrosine | 1989 |
Insulin receptor kinase defects as a possible cause of cellular insulin resistance.
Topics: Adipose Tissue; Animals; Catecholamines; Cell Line; Cell Membrane; Diabetes Mellitus, Type 2; Humans; Insulin Resistance; Melanoma, Experimental; Mice; Muscles; Phorbol Esters; Phosphorylation; Phosphotransferases; Protein-Tyrosine Kinases; Rats; Rats, Zucker; Receptor, Insulin; Tyrosine | 1987 |
Intracellular insulin processing is altered in monocytes from patients with type II diabetes mellitus.
Topics: Aged; Chromatography, Gel; Chromatography, High Pressure Liquid; Diabetes Mellitus, Type 2; Female; Humans; Immunosorbent Techniques; Insulin; Iodides; Iodine Radioisotopes; Kinetics; Male; Middle Aged; Monocytes; Tyrosine | 1987 |