tyrosine has been researched along with Cirrhosis in 53 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 15 (28.30) | 29.6817 |
| 2010's | 31 (58.49) | 24.3611 |
| 2020's | 7 (13.21) | 2.80 |
| Authors | Studies |
|---|---|
| Beckmann, D; Boin, F; Bottini, N; Hansen, U; Holmes, ZJ; Kumar, GS; Lee, MC; Mikulski, Z; Page, R; Peti, W; Sacchetti, C; Santelli, E; Wen, Y; Yang, S; Zhang, R; Zoccheddu, M | 1 |
| Aala, WJ; Chen, YF; Chen, YL; Hou, PC; Hsu, CK; Lin, YC; Lu, HC; McGrath, JA; Onoufriadis, A | 1 |
| Jiang, Y; Liu, X; Tan, Y; Wang, B; Yang, J; Zhan, Z; Zhou, W | 1 |
| Hussain, M; Ikram, U; Ikram, W | 1 |
| Demirci Küçük, K; Furat Rençber, S; Öztürk, A; Yazır, Y; Yüksel, N; Yüksel, R | 1 |
| Abdelgawad, MA; El-Mesery, M; Gomaa, HAM; Hazem, SH; Shaaban, AA; Shaker, ME | 1 |
| Abe, T; Awazu, M; Hashiguchi, A; Hida, M | 1 |
| Bao, Q; Li, G; Liu, C; Suo, Y; Yang, Q; Yuan, M; Zhang, B; Zhang, K; Zhang, Y | 1 |
| Atzler, D; Böger, RH; Chen, P; Chen, Y; Fassett, J; Guo, H; Hu, X; Kwak, D; Liu, X; Lu, Z; Schwedhelm, E; Wang, H; Xu, X; Yue, W; Zhang, P | 1 |
| Fujinaga, T; Hayashi, Y; Hiyama, S; Honma, K; Iijima, H; Maekawa, A; Mizushima, T; Morii, E; Nagai, K; Sakatani, A; Shinzaki, S; Takehara, T; Tsujii, M; Tsujii, Y; Watabe, K; Yoshii, S | 1 |
| Liu, HM; Liu, JD; Ma, N; Wang, XZ; Xia, T | 1 |
| Bernard, NJ | 1 |
| Li, H; Tian, MM; Wang, YY; Yan, XL; Yu, ZF | 1 |
| Chen, L; Li, S; Liu, C; Liu, G; Sun, D; Wang, Y; Wang, Z; Zuo, B | 1 |
| Arguiri, E; Busch, TM; Cengel, KA; Christofidou-Solomidou, M; Dukes, F; Gallagher-Colombo, SM; Pietrofesa, R; Solomides, CC; Turowski, J; Tyagi, S | 1 |
| Edgley, AJ; Fujii, Y; Jenkins, MJ; Joshi, M; Kelly, DJ; Pearson, JT; Schwenke, DO; Shirai, M; Sonobe, T; Tsuchimochi, H; Umetani, K; Waddingham, MT; Yoshimoto, M | 1 |
| Aroor, A; Demarco, VG; Ferrario, CM; Habibi, J; Hayden, MR; Ma, L; Sowers, JR; Whaley-Connell, AT | 1 |
| Chen, X; Fässler, R; Gewin, L; Hu, W; Liao, HJ; Mernaugh, G; Pozzi, A; Vanacore, RM; Vega-Montoto, L; Wang, H; Zent, R; Zhang, S; Zhang, ZY | 1 |
| Bagga, A; Dinda, AK; Sharma, A; Singh, G; Singh, L; Sinha, A | 1 |
| Barnucz, E; Gwanmesia, PN; Hirschberg, K; Korkmaz, S; Li, S; Loganathan, S; Mátyás, C; Merkely, B; Németh, BT; Oláh, A; Páli, S; Radovits, T; Szabó, G; Zubarevich, A | 1 |
| Estes, AM; Fang, XR; Gonzalez, FJ; Jennings, BL; Kanu, A; Malik, KU; Moore, JA; Pingili, AK | 1 |
| Jena, G; Kanika, G; Khan, S | 1 |
| Choi, YH; Han, MH; Hwang, HJ; Kim, BW; Kim, CM; Kim, GY; Kim, JW; Kim, KY; Kim, SG; Ku, SK | 1 |
| Csont, T; Erdélyi, K; Godó, M; Hamar, P; Kaucsár, T; Kiss, N; Kökény, G; Krenács, T; Lajtár, E; Pacher, P; Révész, C; Sárközy, M; Szalay, CI; Szénási, G | 1 |
| Chan, LY; Lai, KN; Lan, HY; Leung, JC; Li, RX; Tang, SC; Wong, DW; Wu, HJ; Yam, I; Yiu, WH | 1 |
| Aguirre, L; Aldámiz-Echevarría, L; Andrade, F; Arbones-Mainar, JM; Carpéné, C; Hasnaoui, M; Hijona, E; Llarena, M; Pérez-Matute, P; Portillo, MP; Villanueva-Millán, MJ | 1 |
| Cao, G; Dominici, FP; Giani, JF; Rivas, C; Toblli, JE | 1 |
| Chen, J; Feng, W; Li, X; Lu, X; Tan, Y; Yan, X; Zeng, J; Zhang, C; Zhang, Z; Zhou, S | 1 |
| Brlecic, P; Brune, M; Karck, M; Korkmaz-Icöz, S; Lehner, A; Li, S; Radovits, T; Ruppert, M; Sun, X; Szabó, G; Vater, A; Zorn, M | 1 |
| Ding, Y; Le, G; Li, ZL; Ran, Y; Shi, Y | 1 |
| Jung, KJ; Kim, J; Park, KM; Seok, YM | 1 |
| Chiou, HY; Lai, SH; Lo, HC; Wang, YH; Yang, Y | 1 |
| Cheng, CF; Cheng, WT; Kikuchi, T; Lian, WS; Lin, H | 1 |
| Bjursten, LM; Chamberlain, L; Faxius, L; Jin, S; Johnston, GW; Smith, GC | 1 |
| Fujita, M; Iwasaka, T; Okazaki, T; Otani, H; Shimazu, T; Yoshioka, K | 1 |
| Alves, SA; Burdmann, EA; Carlos, CP; Coimbra, TM; Luz, MA; Matimoto, RL; Mendes, GE; Oliveira, SM; Souza, RP | 1 |
| Kong, X; Li, WX; Yang, JR; Zhang, JX | 1 |
| Batteux, F; Chéreau, C; Dinh-Xuan, AT; Hua-Huy, T; Kavian, N; Marut, W; Nicco, C; Servettaz, A; Weill, B | 1 |
| Rai, S; Zulli, A | 1 |
| Chen, SS; Lu, L; Quinn, MT; Sun, Y; Weber, KT; Zhang, J | 1 |
| Burns, WC; Cooper, ME; Forbes, JM; Founds, HW; Jerums, G; Thallas, V; Thomas, MC | 1 |
| Colucci, WS; Kotlyar, E; Kuster, GM; Liao, R; Rude, MK; Sam, F; Siwik, DA | 1 |
| Heeg, MH; Koziolek, MJ; Müller, GA; Schaefer, L; Sharma, K; Strutz, F; Vasko, R | 1 |
| Lominadze, D; Moshal, KS; Ovechkin, AV; Tyagi, N; Tyagi, SC | 1 |
| Chan, JY; Chen, CD; Chen, SY; Chiang, TA; Chuang, LY; Guh, JY; Hu, MS; Huang, JS; Hung, MY; Hung, TJ; Lee, TC; Liao, TN; Lin, SH; Liu, HC; Liu, SF; Yang, YL | 1 |
| DePinho, RA; Farazi, PA; Glickman, J; Kalluri, R; Zeisberg, M; Zhang, Y | 1 |
| Galeotti, J; Holle, E; Liu, J; Sadoshima, J; Wagner, T; Yu, X; Zhai, P | 1 |
| Hashimoto, K; Ichihara, G; Ichihara, S; Iwase, M; Kanazawa, H; Kato, Y; Matsushita, A; Oikawa, S; Yamada, Y; Yokota, M | 1 |
| Allen, TJ; Calkin, AC; Cooper, ME; de Haan, JB; Giunti, S; Jandeleit-Dahm, KA; Kola, I; Lewis, P; Pete, J; Stefanovic, N; Thallas-Bonke, V | 1 |
| Ando, S; Araki, H; Fukuhara, S; Inagaki, C; Kawai, K; Otani, H; Yagi, Y | 1 |
| Anilkumar, N; Cave, AC; Grieve, DJ; Looi, YH; Marber, M; Monaghan, MJ; Shah, AM; Siva, A; Walker, SJ | 1 |
| Hibino, Y; Hiraga, K; Kawaguchi, M; Kawai, A; Li, F; Sasahara, M; Tsukada, K; Yamazaki, K | 1 |
| Fujimoto, M; Hamaguchi, Y; Hasegawa, M; Kaburagi, Y; Komura, K; Nagaoka, T; Saito, E; Sato, S; Takehara, K; Tedder, TF | 1 |
2 review(s) available for tyrosine and Cirrhosis
| Article | Year |
|---|---|
Role of c-Src and reactive oxygen species in cardiovascular diseases.
Topics: Cardiovascular Diseases; Fibrosis; Genes, src; Humans; NADPH Oxidases; Oxidation-Reduction; Reactive Oxygen Species; Signal Transduction; Tyrosine | 2023 |
Emerging roles of tyrosine kinases in hepatic inflammatory diseases and therapeutic opportunities.
Topics: Fibrosis; Humans; Liver Diseases; Protein-Tyrosine Kinases; Tyrosine | 2023 |
51 other study(ies) available for tyrosine and Cirrhosis
| Article | Year |
|---|---|
Oxidative stress promotes fibrosis in systemic sclerosis through stabilization of a kinase-phosphatase complex.
Topics: Fibroblasts; Fibrosis; Humans; Oxidative Stress; Scleroderma, Systemic; Tyrosine | 2022 |
Plasma metabolomic profiling reflects the malnourished and chronic inflammatory state in recessive dystrophic epidermolysis bullosa.
Topics: Chromatography, Liquid; Epidermolysis Bullosa Dystrophica; Fibrosis; Glutamates; Glutamine; Humans; Inflammation; Kynurenine; Malnutrition; Phenylalanine; Succinates; Tandem Mass Spectrometry; Tryptophan; Tyrosine | 2022 |
Loss of BTK ameliorates the pathological cardiac fibrosis and dysfunction.
Topics: Agammaglobulinaemia Tyrosine Kinase; Animals; Fibroblasts; Fibrosis; Heart Failure; Mice; Myocardial Infarction; Myocardium; Myofibroblasts; Receptors, Transforming Growth Factor beta; Transforming Growth Factor beta; Tyrosine; Ventricular Remodeling | 2022 |
The anti-scar effect of tyrosine-kinase inhibitor nintedanib in experimental glaucoma filtration surgery in rabbits.
Topics: Animals; Cicatrix; Conjunctiva; Fibrosis; Filtering Surgery; Glaucoma; Intraocular Pressure; Matrix Metalloproteinase 2; Mitomycin; Protein Kinase Inhibitors; Rabbits; Trabeculectomy; Tyrosine | 2023 |
Maternal undernutrition aggravates renal tubular necrosis and interstitial fibrosis after unilateral ureteral obstruction in male rat offspring.
Topics: Animals; Disease Models, Animal; Female; Fibrosis; Kidney; Kidney Tubular Necrosis, Acute; Male; Malnutrition; Maternal-Fetal Exchange; Nitrates; Nitric Oxide; Nitric Oxide Synthase Type III; Nitrites; Oxidative Stress; Pregnancy; Pregnancy Complications; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley; Tyrosine; Ureteral Obstruction | 2019 |
Intermittent hypoxia mediated by TSP1 dependent on STAT3 induces cardiac fibroblast activation and cardiac fibrosis.
Topics: Animals; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; Echocardiography; Fibroblasts; Fibrosis; Gene Expression Regulation; Gene Silencing; Heart; Humans; Hypoxia; Male; Mice; Mice, Inbred C57BL; Myocardium; Phosphorylation; Promoter Regions, Genetic; RNA, Small Interfering; Signal Transduction; STAT3 Transcription Factor; Thrombospondin 1; Tyrosine | 2020 |
Cardiomyocyte dimethylarginine dimethylaminohydrolase-1 (DDAH1) plays an important role in attenuating ventricular hypertrophy and dysfunction.
Topics: Amidohydrolases; Animals; Arginine; Atrial Natriuretic Factor; Disease Models, Animal; Fibrosis; Genetic Predisposition to Disease; Hypertrophy, Left Ventricular; Male; Mice, Knockout; Myocytes, Cardiac; Nitric Oxide; Phenotype; Signal Transduction; Tyrosine; Ventricular Dysfunction, Left; Ventricular Function, Left; Ventricular Remodeling | 2017 |
Adenoma of colorectal laterally spreading tumor nongranular type with biological phenotypic features similar to cancer.
Topics: Adenoma; Carcinogenesis; Cohort Studies; Colorectal Neoplasms; Fibrosis; Humans; Intestinal Mucosa; Ki-67 Antigen; Microvessels; Mucins; Neoplasm Invasiveness; Nitric Oxide Synthase Type II; Phenotype; Retrospective Studies; Tumor Suppressor Protein p53; Tyrosine | 2018 |
Chronic aerobic exercise training alleviates myocardial fibrosis in aged rats through restoring bioavailability of hydrogen sulfide.
Topics: Aging; Animals; Chemokine CCL2; Endoplasmic Reticulum Stress; Fibrosis; Heart; Hydrogen Sulfide; Hydroxyproline; Interleukin-6; Male; Malondialdehyde; Myocardium; Physical Conditioning, Animal; Rats; Sulfides; Tyrosine | 2018 |
A fibrosis checkpoint.
Topics: Fibroblasts; Fibrosis; Humans; Phosphoric Monoester Hydrolases; STAT3 Transcription Factor; Transforming Growth Factor beta; Tyrosine | 2018 |
Peroxisome proliferator-activated receptor-gamma activation attenuates diabetic cardiomyopathy via regulation of the TGF-β/ERK pathway and epithelial-to-mesenchymal transition.
Topics: Animals; Benzophenones; Diabetic Cardiomyopathies; Epithelial-Mesenchymal Transition; Fibrosis; Inflammation; Male; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Myocardium; Peroxisome Proliferator-Activated Receptors; PPAR gamma; Signal Transduction; Transforming Growth Factor beta; Tyrosine | 2018 |
Beraprost sodium mitigates renal interstitial fibrosis through repairing renal microvessels.
Topics: Adult; Animals; Chemokine CCL2; Disease Models, Animal; Epoprostenol; Fibrosis; Human Umbilical Vein Endothelial Cells; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Interleukin-6; Kidney; Kidney Function Tests; Male; Mice, Inbred C57BL; Microvessels; Neovascularization, Physiologic; Regeneration; Transforming Growth Factor beta; Tyrosine; Uncoupling Protein 2; Ureteral Obstruction; Vascular Endothelial Growth Factor A | 2019 |
Radiation mitigating properties of the lignan component in flaxseed.
Topics: Animal Feed; Animals; Bronchoalveolar Lavage Fluid; Butylene Glycols; Cytokines; Female; Fibrosis; Flax; Glucosides; Kaplan-Meier Estimate; Lignans; Lung; Lung Injury; Malondialdehyde; Mice; Mice, Inbred C57BL; Neutrophils; Oxygen; Phytotherapy; Radiation Injuries, Experimental; Radiation Pneumonitis; Radiation-Protective Agents; Seeds; Survival Rate; Time Factors; Transforming Growth Factor beta1; Tyrosine | 2013 |
Acute Rho-kinase inhibition improves coronary dysfunction in vivo, in the early diabetic microcirculation.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Coronary Angiography; Coronary Circulation; Coronary Vessels; Cyclooxygenase Inhibitors; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Epoprostenol; Fibrosis; Male; Microcirculation; Myocardium; Nitric Oxide; Nitric Oxide Synthase; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; rho-Associated Kinases; Tyrosine; Vasoconstriction; Vasodilation; Vasodilator Agents | 2013 |
Salt loading exacerbates diastolic dysfunction and cardiac remodeling in young female Ren2 rats.
Topics: Animals; Collagen; Female; Fibrosis; Fluorescent Antibody Technique; Heart Failure, Diastolic; Hemodynamics; Hypertrophy, Left Ventricular; Magnetic Resonance Imaging; Microscopy, Electron, Transmission; Mitochondria, Heart; Myocardium; Oxidative Stress; Rats; Rats, Sprague-Dawley; Rats, Transgenic; Sodium, Dietary; Tyrosine; Ventricular Function, Left | 2013 |
Integrin-mediated type II TGF-β receptor tyrosine dephosphorylation controls SMAD-dependent profibrotic signaling.
Topics: Animals; Collagen; Epithelial-Mesenchymal Transition; Fibrosis; Integrin alpha1; Integrin alpha1beta1; Kidney; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Phosphorylation; Protein Serine-Threonine Kinases; Protein Tyrosine Phosphatase, Non-Receptor Type 2; Receptor, Transforming Growth Factor-beta Type II; Receptors, Transforming Growth Factor beta; Signal Transduction; Smad Proteins; Smad2 Protein; Smad3 Protein; Tyrosine; Ureteral Obstruction | 2014 |
A comparative study on renal biopsy before and after long-term calcineurin inhibitors therapy: an insight for pathogenesis of its toxicity.
Topics: Adolescent; Atrophy; Biomarkers; Biopsy; Calcineurin Inhibitors; Child; Child, Preschool; Early Diagnosis; Endothelial Cells; Female; Fibrosis; Humans; Hyperplasia; Immunohistochemistry; Immunosuppressive Agents; Infant; Kidney; Kidney Diseases; Kidney Tubules, Proximal; Male; Mitochondria; Nephrotic Syndrome; Nitric Oxide Synthase Type III; Oxidative Stress; Predictive Value of Tests; Time Factors; Transforming Growth Factor beta1; Treatment Outcome; Tyrosine; Up-Regulation | 2015 |
An altered pattern of myocardial histopathological and molecular changes underlies the different characteristics of type-1 and type-2 diabetic cardiac dysfunction.
Topics: Animals; Apoptosis; Diabetes Complications; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Fibrosis; Gene Expression Regulation; Heart; Heart Diseases; Hemodynamics; Immunohistochemistry; In Situ Nick-End Labeling; Male; Myocardium; Oxidative Stress; Rats; Rats, Sprague-Dawley; Rats, Zucker; RNA, Messenger; Transforming Growth Factor beta1; Tyrosine; Ventricular Function, Left | 2015 |
Disruption of the cytochrome P-450 1B1 gene exacerbates renal dysfunction and damage associated with angiotensin II-induced hypertension in female mice.
Topics: Angiotensin II; Animals; Catalase; Cytochrome P-450 CYP1B1; Disease Models, Animal; Drinking; Estradiol; Female; Fibrosis; Genotype; Hypertension; Kidney; Kidney Diseases; Mice, Inbred C57BL; Mice, Knockout; NADPH Oxidases; Natriuresis; Oxidative Stress; Phenotype; Renin-Angiotensin System; Sex Factors; Superoxide Dismutase; Superoxides; Tyrosine; Urination | 2015 |
Sodium Butyrate Ameliorates L-Arginine-Induced Pancreatitis and Associated Fibrosis in Wistar Rat: Role of Inflammation and Nitrosative Stress.
Topics: Animals; Arginine; Butyric Acid; Down-Regulation; Fibrosis; Inflammation; Nitric Oxide Synthase Type II; Pancreas; Pancreatitis; Rats, Wistar; Tyrosine | 2015 |
The administration of Fructus Schisandrae attenuates dexamethasone-induced muscle atrophy in mice.
Topics: Aldehydes; Animals; Anti-Inflammatory Agents; Antioxidants; Creatine; Creatine Kinase; Dexamethasone; Drugs, Chinese Herbal; Fibrosis; L-Lactate Dehydrogenase; Mice; Mice, Inbred ICR; Muscle Proteins; Muscle Strength; Muscle Tonus; Muscle, Skeletal; Muscular Atrophy; Myostatin; Nitric Oxide Synthase Type II; Oxymetholone; Phosphatidylinositol 3-Kinase; Protein Biosynthesis; Proto-Oncogene Proteins c-akt; Receptor, Adenosine A1; RNA, Messenger; Schisandra; Sirtuin 1; SKP Cullin F-Box Protein Ligases; Tripartite Motif Proteins; TRPV Cation Channels; Tyrosine; Ubiquitin-Protein Ligases | 2015 |
Oxidative/Nitrative Stress and Inflammation Drive Progression of Doxorubicin-Induced Renal Fibrosis in Rats as Revealed by Comparing a Normal and a Fibrosis-Resistant Rat Strain.
Topics: Aldehydes; Animals; Body Weight; Chemokine CCL2; Connective Tissue Growth Factor; Disease Progression; Disease Resistance; Dose-Response Relationship, Drug; Doxorubicin; Fibrosis; Kidney; Male; Membrane Proteins; Oxidative Stress; Proteinuria; Rats; Reactive Nitrogen Species; Species Specificity; Transforming Growth Factor beta1; Tyrosine | 2015 |
Kallistatin protects against diabetic nephropathy in db/db mice by suppressing AGE-RAGE-induced oxidative stress.
Topics: Animals; Diabetic Nephropathies; Fibrosis; Gene Transfer Techniques; Genetic Therapy; Kallikreins; Kidney; Kidney Function Tests; Male; Mice, Inbred C57BL; Mice, Transgenic; NADPH Oxidase 4; NADPH Oxidases; Neovascularization, Pathologic; NF-kappa B; Oxidative Stress; Reactive Oxygen Species; Receptor for Advanced Glycation End Products; Serpins; Transforming Growth Factor beta; Tyrosine; Vascular Endothelial Growth Factor A | 2016 |
Potential renoprotective effects of piceatannol in ameliorating the early-stage nephropathy associated with obesity in obese Zucker rats.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Biomarkers; Cell Adhesion Molecules; Dietary Supplements; Fibrosis; Kidney; Lipid Peroxidation; Male; Obesity; Organ Size; Oxidative Stress; Random Allocation; Rats, Zucker; Renal Insufficiency; Severity of Illness Index; Stilbenes; Thiobarbituric Acid Reactive Substances; Tyrosine | 2016 |
Intravenous iron sucrose reverses anemia-induced cardiac remodeling, prevents myocardial fibrosis, and improves cardiac function by attenuating oxidative/nitrosative stress and inflammation.
Topics: Anemia; Animals; Cardiotonic Agents; Ferric Compounds; Ferric Oxide, Saccharated; Fibrosis; Glucaric Acid; Inflammation; Infusions, Intravenous; Male; Myocardium; Oxidative Stress; Rats; Rats, Sprague-Dawley; Tyrosine; Ventricular Remodeling | 2016 |
Fibroblast growth factor 21 deletion aggravates diabetes-induced pathogenic changes in the aorta in type 1 diabetic mice.
Topics: Aldehydes; Animals; Aorta; Aortic Diseases; Apoptosis; Collagen; Connective Tissue Growth Factor; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diabetic Angiopathies; Fibroblast Growth Factors; Fibrosis; Gene Deletion; Genetic Predisposition to Disease; Male; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide Synthase Type III; Oxidative Stress; Phenotype; Signal Transduction; Time Factors; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha; Tyrosine; Vascular Remodeling | 2015 |
Left ventricular pressure-volume measurements and myocardial gene expression profile in type 2 diabetic Goto-Kakizaki rats.
Topics: Animals; Apoptosis; Atrial Natriuretic Factor; Blood Glucose; C-Reactive Protein; Connective Tissue Growth Factor; Diabetes Mellitus, Type 2; Down-Regulation; Echocardiography; Electrocardiography; Fibrosis; Glucose Tolerance Test; Glycosuria; Hypertrophy, Left Ventricular; Immunohistochemistry; In Situ Nick-End Labeling; Inflammation; Interleukin-1beta; Male; Myocardium; Natriuretic Peptide, Brain; Oxidative Stress; Peptide Fragments; Polymerase Chain Reaction; Rats; Rats, Wistar; RNA, Messenger; Signal Transduction; Troponin T; Tumor Necrosis Factor-alpha; Tyrosine; Up-Regulation; Ventricular Dysfunction, Left; Ventricular Function, Left; Ventricular Pressure | 2016 |
Dietary oxidized tyrosine (O-Tyr) stimulates TGF-β1-induced extracellular matrix production via the JNK/p38 signaling pathway in rat kidneys.
Topics: Animals; Fibrosis; Kidney; Male; MAP Kinase Signaling System; Mice, Inbred C57BL; Oxidation-Reduction; Oxidative Stress; Rats, Sprague-Dawley; Transforming Growth Factor beta1; Tyrosine | 2017 |
Reactive oxygen species/oxidative stress contributes to progression of kidney fibrosis following transient ischemic injury in mice.
Topics: Actins; Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Antioxidants; Apoptosis; Collagen; Disease Models, Animal; Disease Progression; Fibrosis; Glucosephosphate Dehydrogenase; HSP47 Heat-Shock Proteins; Hydrogen Peroxide; Ischemia; Kidney; Lipid Peroxidation; Male; Metalloporphyrins; Mice; Mice, Inbred BALB C; Oxidation-Reduction; Oxidative Stress; Proliferating Cell Nuclear Antigen; Reactive Oxygen Species; Reperfusion Injury; S100 Calcium-Binding Protein A4; S100 Proteins; Superoxide Dismutase; Time Factors; Tyrosine; Vitamin E | 2009 |
Relative efficacy of casein or soya protein combined with palm or safflower-seed oil on hyperuricaemia in rats.
Topics: Albumins; Analysis of Variance; Animals; Blood Urea Nitrogen; Caseins; Cholesterol; Creatinine; Diet; Dietary Fats; Dietary Proteins; Dietary Supplements; Drug Therapy, Combination; Fibrosis; Glycine max; Hyperuricemia; Insulin; Interferon-gamma; Kidney; Kidney Calculi; Male; Nephritis, Interstitial; Nitric Oxide; Oxonic Acid; Palm Oil; Plant Oils; Rats; Rats, Wistar; Safflower Oil; Soybean Proteins; Transforming Growth Factor beta; Triglycerides; Tumor Necrosis Factor-alpha; Tyrosine; Uric Acid | 2010 |
Granulocyte-CSF induced inflammation-associated cardiac thrombosis in iron loading mouse heart and can be attenuated by statin therapy.
Topics: Animals; Disease Models, Animal; Endothelial Cells; Fibrosis; Granulocyte Colony-Stimulating Factor; Heart Ventricles; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Iron; Macrophages; Male; Mice; Mice, Inbred C57BL; Myocarditis; Simvastatin; Thrombosis; Tirofiban; Tyrosine | 2011 |
Soft tissue response to titanium dioxide nanotube modified implants.
Topics: Animals; Cell Count; Fibrosis; Implants, Experimental; Macrophages; Male; Nanotubes; Nitric Oxide; Organ Specificity; Rats; Rats, Sprague-Dawley; Silicon Dioxide; Surface Properties; Titanium; Tyrosine | 2011 |
Sepiapterin enhances angiogenesis and functional recovery in mice after myocardial infarction.
Topics: Administration, Oral; Angiogenesis Inducing Agents; Animals; Biopterins; Blood Pressure; Cardiotonic Agents; Disease Models, Animal; Enzyme Inhibitors; Fibrosis; GTP Cyclohydrolase; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardial Infarction; Myocardium; Neovascularization, Physiologic; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Pterins; Recovery of Function; Stroke Volume; Time Factors; Tyrosine; Ultrasonography; Ventricular Function, Left | 2011 |
Previous exposure to cigarette smoke aggravates experimental cyclosporine-induced nephrotoxicity.
Topics: Actins; Animals; Cyclosporine; Disease Models, Animal; Drug Synergism; Fibrosis; Glomerular Filtration Rate; Hematocrit; Hemodynamics; Humans; Immunosuppressive Agents; Kidney; Male; Nephritis, Interstitial; Rats; Rats, Wistar; Smoking; Tyrosine; Vimentin | 2012 |
Long-term intake of sesamin improves left ventricular remodelling in spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Collagen Type I; Dioxoles; Disease Models, Animal; Down-Regulation; Fibrosis; Heart; Hypertension; Hypertrophy, Left Ventricular; Lignans; Male; Malondialdehyde; Myocytes, Cardiac; Rats; Rats, Inbred SHR; Rats, Inbred WKY; RNA, Messenger; Transforming Growth Factor beta1; Tyrosine; Ventricular Remodeling | 2013 |
Amelioration of systemic fibrosis in mice by angiotensin II receptor blockade.
Topics: Administration, Oral; Angiotensin II Type 1 Receptor Blockers; Animals; Biomarkers; Biphenyl Compounds; Breath Tests; Disease Models, Animal; Female; Fibrosis; Hypochlorous Acid; Injections, Intradermal; Irbesartan; Lung; Mice; Mice, Inbred BALB C; Nitric Oxide; Nitric Oxide Synthase Type II; Oxidants; Pulmonary Fibrosis; Scleroderma, Systemic; Skin; Tetrazoles; Tyrosine | 2013 |
Lack of cell stress markers in fibrous cap cells in the left main coronary artery.
Topics: Animals; Biomarkers; Coronary Artery Disease; Coronary Vessels; Disease Models, Animal; Endoplasmic Reticulum Chaperone BiP; Endothelial Cells; Fibrosis; Heat-Shock Proteins; Heme Oxygenase-1; HSP70 Heat-Shock Proteins; HSP90 Heat-Shock Proteins; Immunohistochemistry; Male; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Nitric Oxide Synthase Type II; Plaque, Atherosclerotic; Rabbits; Stress, Physiological; Transcription Factor CHOP; Tyrosine | 2013 |
Aldosterone-induced inflammation in the rat heart : role of oxidative stress.
Topics: Aldosterone; Animals; Antioxidants; Cardiomyopathies; Cell Division; Cell Movement; Fibrosis; Heart; Immunologic Factors; Inflammation; Lymphocytes; Macrophages; Male; Mineralocorticoid Receptor Antagonists; Monocytes; Myocardium; NADPH Oxidases; NF-kappa B; Oxidative Stress; Rats; Rats, Sprague-Dawley; RNA, Messenger; Spironolactone; Tyrosine | 2002 |
The breakdown of preexisting advanced glycation end products is associated with reduced renal fibrosis in experimental diabetes.
Topics: Albuminuria; Animal Population Groups; Animals; Blood Pressure; Collagen; Connective Tissue Growth Factor; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Fibrosis; Glycation End Products, Advanced; Immediate-Early Proteins; Immunohistochemistry; Intercellular Signaling Peptides and Proteins; Kidney; Kinetics; Lysine; Models, Biological; Rats; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Solubility; Thiazoles; Transforming Growth Factor beta; Transforming Growth Factor beta1; Tyrosine | 2003 |
Mineralocorticoid receptor inhibition ameliorates the transition to myocardial failure and decreases oxidative stress and inflammation in mice with chronic pressure overload.
Topics: Animals; Aorta; Apoptosis; Blood Pressure; Cell Size; Chronic Disease; Constriction, Pathologic; Drug Evaluation, Preclinical; Eplerenone; Fibrosis; Heart Failure; Hypertrophy, Left Ventricular; Intercellular Adhesion Molecule-1; Ligation; Male; Matrix Metalloproteinases; Mice; Mineralocorticoid Receptor Antagonists; Myocarditis; Myocardium; Myocytes, Cardiac; Oxidative Stress; Pressure; Random Allocation; Receptors, Mineralocorticoid; Spironolactone; Tissue Inhibitor of Metalloproteinase-1; Tissue Inhibitor of Metalloproteinase-2; Tyrosine | 2005 |
The antifibrotic effects of relaxin in human renal fibroblasts are mediated in part by inhibition of the Smad2 pathway.
Topics: Apoptosis; Cell Division; Cell Line; DNA-Binding Proteins; Extracellular Matrix; Fibroblasts; Fibrosis; Humans; Kidney; MAP Kinase Signaling System; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Necrosis; Phosphorylation; Receptors, Transforming Growth Factor beta; Relaxin; Smad2 Protein; Smad3 Protein; Trans-Activators; Transforming Growth Factor beta; Transforming Growth Factor beta1; Tyrosine | 2005 |
Homocysteine-dependent cardiac remodeling and endothelial-myocyte coupling in a 2 kidney, 1 clip Goldblatt hypertension mouse model.
Topics: Acetylcholine; Animals; Blotting, Western; Collagen; Endothelin-1; Endothelium, Vascular; Fibrosis; Homocysteine; Hypertension, Renovascular; Hypoglycemic Agents; Kidney; Male; Matrix Metalloproteinases; Mice; Mice, Inbred C57BL; Myocardial Contraction; Myocytes, Cardiac; Nitroprusside; PPAR gamma; Proteinuria; Thiazolidinediones; Tissue Inhibitor of Metalloproteinase-1; Tyrosine; Vasodilator Agents; Ventricular Remodeling | 2005 |
Albumin induces cellular fibrosis by upregulating transforming growth factor-beta ligand and its receptors in renal distal tubule cells.
Topics: Albumins; Animals; Cell Line; Cell Proliferation; Cell Size; Dogs; Dose-Response Relationship, Drug; Drug Synergism; Fibronectins; Fibrosis; Kidney Tubules, Distal; Ligands; Phosphorylation; Protein Binding; Receptors, Transforming Growth Factor beta; Transforming Growth Factor beta; Tyrosine; Up-Regulation | 2006 |
Chronic bile duct injury associated with fibrotic matrix microenvironment provokes cholangiocarcinoma in p53-deficient mice.
Topics: Animals; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Cadherins; Carbon Tetrachloride Poisoning; Cholangiocarcinoma; Cyclooxygenase 2; Extracellular Matrix; Female; Fibrosis; Germ-Line Mutation; Hyperplasia; Liver Cirrhosis; Male; Mice; Mice, Inbred C57BL; Nitric Oxide Synthase Type II; Proto-Oncogene Proteins c-met; Receptor, ErbB-2; Tumor Suppressor Protein p53; Tyrosine | 2006 |
An angiotensin II type 1 receptor mutant lacking epidermal growth factor receptor transactivation does not induce angiotensin II-mediated cardiac hypertrophy.
Topics: Angiotensin II; Animals; Apoptosis; Cardiomegaly; Diastole; Echocardiography; ErbB Receptors; Fibrosis; Genes, Dominant; Heart; Mice; Mice, Transgenic; Mutation; Myocardium; Phenylalanine; Receptor, Angiotensin, Type 1; Transcriptional Activation; Tyrosine; Ventricular Function, Left | 2006 |
Attenuation of oxidative stress and cardiac dysfunction by bisoprolol in an animal model of dilated cardiomyopathy.
Topics: Aldehydes; Animals; Antioxidants; Bisoprolol; Blood Pressure; Body Weight; Cardiomyopathy, Dilated; Cricetinae; Disease Models, Animal; Echocardiography; Fibrosis; Glutathione; Heart Failure; Heart Rate; Interleukin-1; Isoenzymes; Male; NADPH Oxidases; Organ Size; Oxidative Stress; Superoxide Dismutase; Tumor Necrosis Factor-alpha; Tyrosine; Ventricular Function, Left | 2006 |
Lack of the antioxidant enzyme glutathione peroxidase-1 accelerates atherosclerosis in diabetic apolipoprotein E-deficient mice.
Topics: Animals; Aorta; Aortic Diseases; Apolipoproteins E; Atherosclerosis; Connective Tissue Growth Factor; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Fibrosis; Gene Expression Regulation; Glutathione; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Hyperlipoproteinemia Type II; Immediate-Early Proteins; Inflammation; Intercellular Signaling Peptides and Proteins; Isoenzymes; Macrophages; Male; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Mice, Knockout; NADPH Oxidase 2; NADPH Oxidases; NF-kappa B; Oxidation-Reduction; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Sinus of Valsalva; Streptozocin; Superoxide Dismutase; Tyrosine; Vascular Cell Adhesion Molecule-1; Vascular Endothelial Growth Factor A | 2007 |
Proteinase-activated receptor 4 stimulation-induced epithelial-mesenchymal transition in alveolar epithelial cells.
Topics: Actins; Animals; Blotting, Western; Cadherins; Cell Shape; Cells, Cultured; Epithelial Cells; ErbB Receptors; Fibroblasts; Fibrosis; Humans; Immunohistochemistry; Mesoderm; Mice; Mice, Inbred C57BL; Muscle, Smooth; Oligopeptides; Phenotype; Phosphorylation; Pulmonary Alveoli; Receptors, Thrombin; src-Family Kinases; Thrombin; Time Factors; Tyrosine | 2007 |
Involvement of Nox2 NADPH oxidase in adverse cardiac remodeling after myocardial infarction.
Topics: Animals; Apoptosis; Cardiac Catheterization; Cardiomegaly; Echocardiography; Fibrosis; Matrix Metalloproteinase 2; Membrane Glycoproteins; Mice; Mice, Knockout; Myocardial Infarction; Myocardium; NADPH Oxidase 2; NADPH Oxidase 4; NADPH Oxidases; RNA, Messenger; Staining and Labeling; Survival Analysis; Tyrosine; Ventricular Remodeling | 2008 |
Simultaneous induction of galectin-3 phosphorylated on tyrosine residue, p21(WAF1/Cip1/Sdi1), and the proliferating cell nuclear antigen at a distinctive period of repair of hepatocytes injured by CCl4.
Topics: Animals; Antigens, Differentiation; Blotting, Northern; Carbon Tetrachloride; Cloning, Molecular; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Cytoplasm; Fibrosis; Galectin 3; Hepatocytes; Immunoblotting; Immunohistochemistry; Liver; Phosphorylation; Phosphotyrosine; Proliferating Cell Nuclear Antigen; Rats; Rats, Wistar; Signal Transduction; Time Factors; Tyrosine | 2001 |
CD19-dependent B lymphocyte signaling thresholds influence skin fibrosis and autoimmunity in the tight-skin mouse.
Topics: ADP-ribosyl Cyclase; ADP-ribosyl Cyclase 1; Animals; Antigens, CD; Antigens, CD19; Antigens, Differentiation; B-Lymphocytes; Blotting, Western; Calcium; Disease Models, Animal; Dose-Response Relationship, Drug; Down-Regulation; Enzyme-Linked Immunosorbent Assay; Fibrosis; Flow Cytometry; Humans; Hydroxyproline; Immunoglobulin M; Interleukin-6; Membrane Glycoproteins; Mice; NAD+ Nucleosidase; Phosphorylation; Precipitin Tests; Scleroderma, Systemic; Signal Transduction; Skin; Time Factors; Tyrosine; Up-Regulation | 2002 |