tyrosine has been researched along with Cancer of Pancreas in 51 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (11.76) | 18.7374 |
| 1990's | 13 (25.49) | 18.2507 |
| 2000's | 16 (31.37) | 29.6817 |
| 2010's | 12 (23.53) | 24.3611 |
| 2020's | 4 (7.84) | 2.80 |
| Authors | Studies |
|---|---|
| Ali, DW; Chen, XZ; Deng, X; Dong, X; Hu, M; Huang, H; Huang, Y; Li, S; Liu, N; Liu, S; Luo, S; Lyu, H; Michalak, M; Tang, J; Tang, Y; Wang, M; Wang, Z; Xiao, S; Zhang, R; Zhang, X; Zhou, C; Zhu, X | 1 |
| Cai, X; Li, S; Singhi, AD; Tang, D; Wang, Z; Xie, W; Xu, M; Yang, D; Yates, NA; Zeng, X | 1 |
| Pasca di Magliano, M; Zhang, Y | 1 |
| Aoki, M; Hatazawa, J; Horitsugi, G; Ikeda, H; Kanai, Y; Kongpracha, P; Nagamori, S; Naka, S; Shimosegawa, E; Watabe, T | 1 |
| Inohara, H; Jin, C; Kanai, Y; Liu, X; Miyabe, J; Nagamori, S; Ohgaki, R; Ohki, H; Okuda, S; Quan, L; Saito, K; Wei, L; Yoshino, K | 1 |
| Han, J; Huang, Y; Jin, H; Liu, P; Liu, X; Meng, X; Tan, X; Wu, Y; Yu, B | 1 |
| Reubi, JC; Waser, B | 1 |
| Acoba, J; Furuya, H; Paladino, D; Rosser, CJ; Turkson, J; Yue, P | 1 |
| Fujii, H; Kusama, T; Okamoto, H | 1 |
| Abe, M; Akiba, J; Ikezono, Y; Iwamoto, H; Koga, H; Masuda, A; Nakamura, T; Sakaue, T; Torimura, T; Tsuruta, O; Wada, F; Yano, H; Yoshida, T | 1 |
| Cao, L; Freeman, JW; Jin, C; Lazor, JW; Sperry, J; Venkatasubbarao, K; Zhao, S | 1 |
| Buck, AK; Eckel, F; Friess, H; Herrmann, K; Kleeff, J; Krause, BJ; Scheidhauer, K; Schmid, RM; Schmidt, S; Schuster, T; Schwaiger, M; Wester, HJ | 1 |
| Aulak, KS; Corbett, JA; Crabb, JW; Koeck, T; Stuehr, DJ | 1 |
| Farago, M; Katzav, S; Lazer, G; Machida, K; Mayer, BJ; Pe'er, L | 1 |
| Fujii, S; Hiraoka, N; Kanai, Y; Kosuge, T; Miyazawa, Y; Nojima, Y; Sakai, R; Uekita, T | 1 |
| Bajaj, E; Besmer, D; Gendler, SJ; Hwang, SI; Lee, YY; Mukherjee, P; Nath, S; Roy, LD; Sahraei, M; Shanmugam, K; Subramani, DB; Tinder, TL | 1 |
| Anders, RA; Edil, BH; Foley, K; Huang, L; Illei, PB; Jaffee, EM; Laheru, D; Le, DT; Leubner, A; Maitra, A; Mizuma, M; Mo, G; Olino, K; Sharma, R; Van Eyk, JE; Zheng, L | 1 |
| Etoh, H; Hosokawa, M; Kato, H; Kato, K; Maejima, Y; Maoka, T; Matsumoto, G; Miyashita, K; Mori, H; Nakatugawa, H; Suzuki, N; Tokuda, H; Tsuboi, M | 1 |
| Delle Fave, G; Di Florio, A; Jensen, RT; Moreno, P; Sancho, V | 1 |
| Brattain, MG; DeArmond, D; Freeman, JW; Jessup, JM; Kreisberg, J; Malik, S; Zhao, S | 1 |
| Ashley, SW; Duxbury, MS; Ito, H; Whang, EE; Zinner, MJ | 1 |
| Fidler, IJ; Yokoi, K | 1 |
| Bhagroo, NV; Brelje, TC; Sorenson, RL; Stout, LE | 1 |
| Cao, P; Gronda, M; Hedley, DW; Jacobberger, JW; Pham, NA; Schimmer, AD | 1 |
| Choudary, A; Freeman, JW; Venkatasubbarao, K | 1 |
| Dufresne, M; Estève, JP; Ferrand, A; Fourmy, D; Kowalski-Chauvel, A; Lopez, F; Seva, C; Vatinel, S | 1 |
| Cerny, RL; Gendler, SJ; Hollingsworth, MA; Kazlauskas, A; Shanmugam, K; Singh, PK; Swanson, BJ; Wen, Y | 1 |
| Billadeau, DD; Bramati, P; Chatterjee, S; Hedin, K; Shah, V; Sreekumar, R; Urrutia, R | 1 |
| Hill, MJ | 1 |
| Bayna, EM; Cheresh, DA; Klemke, RL; Yebra, M | 1 |
| Dye, JF; Gillespie, J; Guillou, PJ; Schachter, M | 1 |
| Akedo, H; Imamura, F; Isoai, A; Kitagawa, I; Kobayashi, M; Mukai, M; Shinkai, K | 1 |
| Büchler, MW; Cao, T; Fan, HU; Hope, C; Kobrin, MS; Korc, M; Lopez, ME; van Nostrand, K; Wagner, M | 1 |
| Brooks, PC; Cheresh, DA; Klemke, RL; Leng, J; Molander, R; Vuori, K | 1 |
| Ashford, ML; Harvey, J | 1 |
| Adler, G; Flossmann-Kast, BB; Hoeflich, A; Jehle, PM; Lutz, MP | 1 |
| Ellis, C; Green, M; MacMillan-Crow, LA; Thompson, JA; Vickers, SM | 1 |
| Barazzoni, R; Tessari, P; Tiengo, A; Zanetti, M | 1 |
| Greendorfer, JS; MacMillan-Crow, LA; Thompson, JA; Vickers, SM | 1 |
| Benali, N; Buscail, L; Calise, D; Cordelier, P; Esteve, JP; Nagy, A; Pages, P; Pour, PM; Rochaix, P; Schally, AV; Susini, C; Vaysse, N | 1 |
| Adrian, TE; Ding, XZ; Tong, WG | 1 |
| El-Hariry, I; Lemoine, NR; Pignatelli, M | 1 |
| Payne, RB; Salway, JG | 1 |
| Arvanitakis, C; Greenberger, NJ | 1 |
| Kamer, AR; Lee, MT; Liebow, C; Schally, AV | 1 |
| Chandrasekar, B; Korc, M; Shah, GN | 1 |
| Bakker, WH; Krenning, EP; Lamberts, SW; Reubi, JC | 1 |
| Hirai, M; Kobayashi, M; Shimizu, N | 1 |
| Ewen, SW; Pearse, AG; Polak, JM | 1 |
| Godal, HC; Kierulf, P | 1 |
| Arkhipenko, VI; Spitsa, AI | 1 |
1 review(s) available for tyrosine and Cancer of Pancreas
| Article | Year |
|---|---|
Bacterial metabolism and human carcinogenesis.
Topics: Bacteria; Bile Acids and Salts; Biliary Tract Neoplasms; Cholesterol; Female; Gastrointestinal Neoplasms; Humans; Neoplasms; Nitrosamines; Nitroso Compounds; Pancreatic Neoplasms; Phenols; Schistosomiasis; Tryptophan; Tyrosine; Urinary Bladder Neoplasms; Uterine Cervical Neoplasms | 1980 |
50 other study(ies) available for tyrosine and Cancer of Pancreas
| Article | Year |
|---|---|
B-lymphoid tyrosine kinase-mediated FAM83A phosphorylation elevates pancreatic tumorigenesis through interacting with β-catenin.
Topics: beta Catenin; Carcinogenesis; Cell Transformation, Neoplastic; Humans; Neoplasm Proteins; Pancreatic Neoplasms; Phosphorylation; src-Family Kinases; Tyrosine; Wnt Signaling Pathway | 2023 |
Inhibition of the SLC35B2-TPST2 Axis of Tyrosine Sulfation Attenuates the Growth and Metastasis of Pancreatic Ductal Adenocarcinom.
Topics: Animals; Carcinoma, Pancreatic Ductal; Humans; Integrin beta4; Membrane Proteins; Mice; Pancreatic Neoplasms; Sulfate Transporters; Sulfotransferases; Tyrosine | 2023 |
Tyrosine Sulfation: A New Player and Potential Target in Pancreatic Cancer.
Topics: Amino Acid Sequence; Humans; Pancreatic Neoplasms; Tyrosine | 2023 |
Distribution of LAT1-targeting PET tracer was independent of the tumor blood flow in rat xenograft models of C6 glioma and MIA PaCa-2.
Topics: Animals; Blood Circulation; Boron Compounds; Cell Line, Tumor; Cell Transformation, Neoplastic; Glioma; Humans; Large Neutral Amino Acid-Transporter 1; Male; Pancreatic Neoplasms; Phenylalanine; Positron-Emission Tomography; Radioactive Tracers; Radiopharmaceuticals; Rats; Tissue Distribution; Tyrosine | 2019 |
Boron delivery for boron neutron capture therapy targeting a cancer-upregulated oligopeptide transporter.
Topics: Animals; Biological Transport; Boron Compounds; Boron Neutron Capture Therapy; Cell Line, Tumor; Female; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Pancreatic Neoplasms; Peptide Transporter 1; Phenylalanine; Symporters; Tyrosine; Up-Regulation; Xenograft Model Antitumor Assays | 2019 |
Integrin beta 4 (ITGB4) and its tyrosine-1510 phosphorylation promote pancreatic tumorigenesis and regulate the MEK1-ERK1/2 signaling pathway.
Topics: Carcinogenesis; Cell Movement; Humans; Integrin beta4; MAP Kinase Signaling System; Neoplasm Invasiveness; Pancreatic Neoplasms; Phosphorylation; Tyrosine | 2020 |
Triple-peptide receptor targeting in vitro allows detection of all tested gut and bronchial NETs.
Topics: Autoradiography; Bronchial Neoplasms; Glucagon-Like Peptide-1 Receptor; Humans; Insulinoma; Iodine Radioisotopes; Ligands; Neoplasm Metastasis; Neuroendocrine Tumors; Octreotide; Pancreatic Neoplasms; Protein Binding; Receptors, Gastrointestinal Hormone; Receptors, Glucagon; Receptors, Peptide; Receptors, Somatostatin; Tyrosine | 2015 |
A novel nuclear Src and p300 signaling axis controls migratory and invasive behavior in pancreatic cancer.
Topics: Animals; Apoptosis; Blotting, Western; Carcinoma, Pancreatic Ductal; Cell Movement; Cell Nucleus; Cell Proliferation; Cells, Cultured; Chromatin Immunoprecipitation; E1A-Associated p300 Protein; Embryo, Mammalian; Fibroblasts; Fluorescent Antibody Technique; Humans; Immunoenzyme Techniques; Immunoprecipitation; Mice; Neoplasm Invasiveness; Pancreatic Neoplasms; Phosphorylation; Proto-Oncogene Proteins pp60(c-src); Signal Transduction; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tyrosine; Wound Healing | 2016 |
Tyrosine Phosphorylation of Focal Adhesion Anchoring Proteins Enhances Human Pancreatic Cancer Cell Invasion.
Topics: Animals; Blotting, Western; Cattle; Cell Line; Cell Line, Tumor; Cell Movement; Crk-Associated Substrate Protein; Endothelial Cells; Enzyme Inhibitors; Focal Adhesion Protein-Tyrosine Kinases; Humans; Neoplasm Invasiveness; Pancreatic Neoplasms; Phosphorylation; Pulmonary Artery; Rifabutin; Tyrosine | 2016 |
Pancreatic Neuroendocrine Tumors and EMT Behavior Are Driven by the CSC Marker DCLK1.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Animals; Biomarkers, Tumor; Cell Line, Tumor; Doublecortin-Like Kinases; Epithelial-Mesenchymal Transition; Female; Focal Adhesion Kinase 1; Humans; Intracellular Signaling Peptides and Proteins; Male; Mice, Inbred BALB C; Middle Aged; Neoplastic Stem Cells; Neuroendocrine Tumors; Pancreatic Neoplasms; Protein Serine-Threonine Kinases; Tyrosine; Xenograft Model Antitumor Assays | 2017 |
Inhibition of STAT3 Tyr705 phosphorylation by Smad4 suppresses transforming growth factor beta-mediated invasion and metastasis in pancreatic cancer cells.
Topics: Blotting, Western; Cell Line, Tumor; Extracellular Signal-Regulated MAP Kinases; Humans; Neoplasm Invasiveness; Neoplasm Metastasis; Pancreatic Neoplasms; Phosphorylation; Smad4 Protein; STAT3 Transcription Factor; Transforming Growth Factor beta; Tyrosine | 2008 |
In vivo characterization of proliferation for discriminating cancer from pancreatic pseudotumors.
Topics: Adult; Aged; Diagnosis, Differential; Female; Granuloma, Plasma Cell; Humans; Image Interpretation, Computer-Assisted; Male; Middle Aged; Neoplasm Invasiveness; Pancreatic Neoplasms; Radionuclide Imaging; Radiopharmaceuticals; Reproducibility of Results; Sensitivity and Specificity; Tyrosine | 2008 |
Glucose-modulated tyrosine nitration in beta cells: targets and consequences.
Topics: Animals; Chaperonin 60; Diabetes Mellitus; Glucose; Humans; Hyperglycemia; Insulin; Insulin Secretion; Insulin-Secreting Cells; Insulinoma; Islets of Langerhans; Nitrates; Pancreatic Neoplasms; Prediabetic State; Tyrosine | 2009 |
Tyrosine residues at the carboxyl terminus of Vav1 play an important role in regulation of its biological activity.
Topics: Amino Acid Sequence; Amino Acid Substitution; Animals; Cattle; Cell Transformation, Neoplastic; Enzyme Activation; Humans; Jurkat Cells; Mice; Molecular Sequence Data; Mutation; NFATC Transcription Factors; Pancreatic Neoplasms; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-vav; Rats; T-Lymphocytes; Tyrosine | 2010 |
CUB domain-containing protein 1, a prognostic factor for human pancreatic cancers, promotes cell migration and extracellular matrix degradation.
Topics: Antigens, CD; Antigens, Neoplasm; Blotting, Western; Cell Adhesion; Cell Adhesion Molecules; Cell Movement; Cell Proliferation; Cortactin; Extracellular Matrix; Humans; Immunoenzyme Techniques; Immunoprecipitation; Lymphatic Metastasis; Matrix Metalloproteinase 9; Neoplasm Invasiveness; Neoplasm Proteins; Pancreatic Neoplasms; Phosphorylation; Prognosis; Protein Kinase C-delta; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; RNA, Small Interfering; Survival Rate; Tumor Cells, Cultured; Tyrosine | 2010 |
MUC1 enhances invasiveness of pancreatic cancer cells by inducing epithelial to mesenchymal transition.
Topics: Amino Acid Sequence; Animals; Cadherins; Cell Line, Tumor; Epithelial-Mesenchymal Transition; Humans; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Mucin-1; Neoplasm Invasiveness; Neoplasm Metastasis; Pancreatic Neoplasms; Snail Family Transcription Factors; Transcription Factors; Tyrosine | 2011 |
Tyrosine 23 phosphorylation-dependent cell-surface localization of annexin A2 is required for invasion and metastases of pancreatic cancer.
Topics: Animals; Annexin A2; Antibodies, Monoclonal; Antigens, Neoplasm; Biomarkers, Tumor; Blotting, Western; Cancer Vaccines; Cell Line, Tumor; Cell Membrane; Cell Movement; Disease-Free Survival; Epithelial-Mesenchymal Transition; Female; Humans; Liver; Mice; Mice, Inbred C57BL; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasms, Experimental; Pancreatic Neoplasms; Phosphorylation; RNA Interference; Tumor Cells, Cultured; Tyrosine | 2011 |
Nitrocapsanthin and nitrofucoxanthin, respective products of capsanthin and fucoxanthin reaction with peroxynitrite.
Topics: Animals; Anticarcinogenic Agents; Burkitt Lymphoma; Cell Line, Tumor; Female; Free Radical Scavengers; Humans; Mice; Mice, Inbred ICR; Pancreatic Neoplasms; Papilloma; Peroxynitrous Acid; Skin Neoplasms; Tyrosine; Xanthophylls | 2011 |
Gastrointestinal hormones stimulate growth of Foregut Neuroendocrine Tumors by transactivating the EGF receptor.
Topics: Adenoma, Islet Cell; Animals; Blotting, Western; Cell Proliferation; Epidermal Growth Factor; ErbB Receptors; Gastrointestinal Hormones; Humans; Neuroendocrine Tumors; Pancreatic Neoplasms; Phosphorylation; Rats; Reactive Oxygen Species; Signal Transduction; Somatostatinoma; Transcriptional Activation; Transforming Growth Factor alpha; Tumor Cells, Cultured; Tyrosine | 2013 |
Autocrine-mediated ErbB-2 kinase activation of STAT3 is required for growth factor independence of pancreatic cancer cell lines.
Topics: CDC2-CDC28 Kinases; Cell Cycle Proteins; Cell Line, Tumor; Cyclin D1; Cyclin-Dependent Kinase 2; Cyclin-Dependent Kinase Inhibitor p27; DNA-Binding Proteins; ErbB Receptors; Growth Substances; Humans; Pancreatic Neoplasms; Phosphorylation; Receptor, ErbB-2; Retinoblastoma Protein; STAT3 Transcription Factor; Trans-Activators; Tumor Suppressor Proteins; Tyrosine | 2003 |
Inhibition of SRC tyrosine kinase impairs inherent and acquired gemcitabine resistance in human pancreatic adenocarcinoma cells.
Topics: Adenocarcinoma; Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Apoptosis; Blotting, Northern; Blotting, Western; Caspases; Cell Cycle Proteins; Cell Division; Cell Line, Tumor; Cell Nucleus; Deoxycytidine; DNA-Binding Proteins; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; E2F Transcription Factors; E2F1 Transcription Factor; Gemcitabine; Genes, Dominant; Humans; Inhibitory Concentration 50; Mice; Mice, Nude; Neoplasm Metastasis; Neoplasm Transplantation; Pancreatic Neoplasms; Phosphorylation; Pyrimidines; Ribonucleoside Diphosphate Reductase; src-Family Kinases; Transcription Factors; Tyrosine | 2004 |
Hypoxia increases resistance of human pancreatic cancer cells to apoptosis induced by gemcitabine.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Apoptosis; Blotting, Western; Butadienes; Cell Division; Cell Line, Tumor; Chromones; Deoxycytidine; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Gemcitabine; Humans; Hypoxia; Mitogen-Activated Protein Kinases; Morpholines; Neovascularization, Pathologic; NF-kappa B; Nitriles; Oxygen; Pancreatic Neoplasms; Phosphatidylinositol 3-Kinases; Phosphorylation; Protein-Tyrosine Kinases; Pyrimidines; Pyrroles; Signal Transduction; Sp1 Transcription Factor; Time Factors; Tyrosine | 2004 |
Distinctive roles for prolactin and growth hormone in the activation of signal transducer and activator of transcription 5 in pancreatic islets of langerhans.
Topics: Animals; Cell Division; Cell Line, Tumor; DNA-Binding Proteins; Growth Hormone; Insulinoma; Islets of Langerhans; Janus Kinase 2; Kinetics; Milk Proteins; Pancreatic Neoplasms; Phosphorylation; Prolactin; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Rats; Signal Transduction; STAT5 Transcription Factor; Trans-Activators; Tyrosine | 2004 |
The dietary isothiocyanate sulforaphane targets pathways of apoptosis, cell cycle arrest, and oxidative stress in human pancreatic cancer cells and inhibits tumor growth in severe combined immunodeficient mice.
Topics: Animals; Anticarcinogenic Agents; Antigens; Apoptosis; Blotting, Western; Caspase 3; Caspase 8; Caspases; Cell Cycle; Cell Line, Tumor; Cell Membrane; Cell Nucleus; DNA; Dose-Response Relationship, Drug; Enzyme Activation; Flow Cytometry; Glutathione; Humans; Isothiocyanates; Male; Membrane Potentials; Mice; Mice, SCID; Microscopy, Fluorescence; Mitochondria; Mitosis; Neoplasm Transplantation; Neoplasms; Oxidative Stress; Pancreatic Neoplasms; Reactive Oxygen Species; Staurosporine; Sulfoxides; Thiocyanates; Time Factors; Tyrosine | 2004 |
Farnesyl transferase inhibitor (R115777)-induced inhibition of STAT3(Tyr705) phosphorylation in human pancreatic cancer cell lines require extracellular signal-regulated kinases.
Topics: Adenocarcinoma; Alkyl and Aryl Transferases; Cell Cycle Proteins; Cell Growth Processes; Cyclin-Dependent Kinase Inhibitor p21; DNA-Binding Proteins; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Farnesyltranstransferase; Humans; Interleukin-6; Pancreatic Neoplasms; Phosphorylation; Proto-Oncogene Proteins c-myc; Quinolones; Serine; STAT3 Transcription Factor; Trans-Activators; Tyrosine; Up-Regulation | 2005 |
An ITIM-like motif within the CCK2 receptor sequence required for interaction with SHP-2 and the activation of the AKT pathway.
Topics: Amino Acid Motifs; Amino Acid Sequence; Animals; Cell Line, Tumor; Chlorocebus aethiops; COS Cells; Gastrins; Intracellular Signaling Peptides and Proteins; Mice; Molecular Sequence Data; NIH 3T3 Cells; Pancreatic Neoplasms; Phosphorylation; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins c-akt; Rats; Receptor, Cholecystokinin B; Signal Transduction; Tyrosine | 2006 |
Platelet-derived growth factor receptor beta-mediated phosphorylation of MUC1 enhances invasiveness in pancreatic adenocarcinoma cells.
Topics: Adenocarcinoma; Amino Acid Motifs; Amino Acid Sequence; Animals; Antigens, Neoplasm; beta Catenin; Binding Sites; Cell Line, Tumor; Cell Nucleus; Female; Humans; Mass Spectrometry; Mice; Mice, Nude; Molecular Sequence Data; Mucin-1; Mucins; Neoplasm Invasiveness; Pancreatic Neoplasms; Phosphorylation; Receptor, Platelet-Derived Growth Factor beta; Tyrosine | 2007 |
Characterization of the CXCR4 signaling in pancreatic cancer cells.
Topics: Aorta; Blotting, Western; Cell Adhesion; Cell Movement; Cell Proliferation; Endothelium, Vascular; Enzyme Inhibitors; ErbB Receptors; Gene Expression Profiling; Humans; Hyaluronan Receptors; Hypoxia-Inducible Factor 1, alpha Subunit; Immunoprecipitation; Interleukin-8; MAP Kinase Signaling System; Neovascularization, Physiologic; Oligonucleotide Array Sequence Analysis; Pancreatic Neoplasms; Phosphatidylinositol 3-Kinases; Phosphorylation; Receptors, CXCR4; Signal Transduction; Tyrosine; Vascular Endothelial Growth Factor A | 2006 |
Receptor tyrosine kinase signaling required for integrin alpha v beta 5-directed cell motility but not adhesion on vitronectin.
Topics: Cell Adhesion; Cell Line; Cell Movement; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; Flow Cytometry; Genistein; Glycoproteins; Humans; Insulin-Like Growth Factor I; Integrins; Isoflavones; Kinetics; Naphthalenes; Nitriles; Pancreatic Neoplasms; Phosphotyrosine; Polycyclic Compounds; Protein Kinase C; Receptor Protein-Tyrosine Kinases; Receptor, IGF Type 1; Receptors, Vitronectin; Signal Transduction; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tyrosine; Tyrphostins; Vitronectin | 1994 |
Inhibition of pancreatic cancer cell growth in vitro by the tyrphostin group of tyrosine kinase inhibitors.
Topics: Catechols; Cell Division; DNA, Neoplasm; Dose-Response Relationship, Drug; Epidermal Growth Factor; Humans; Immunoblotting; Nitriles; Pancreatic Ducts; Pancreatic Neoplasms; Phenols; Phosphorylation; Platelet-Derived Growth Factor; Protein-Tyrosine Kinases; Tumor Cells, Cultured; Tyrosine; Tyrphostins | 1993 |
Inhibition of in vitro tumor cell invasion by ginsenoside Rg3.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Carbohydrate Sequence; Carcinoma, Small Cell; Ginsenosides; Humans; Liver Neoplasms, Experimental; Lung Neoplasms; Lysophospholipids; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Proteins; Pancreatic Neoplasms; Phosphorylation; Rats; Rats, Inbred Strains; Saponins; Tyrosine | 1996 |
Expression of a truncated EGF receptor is associated with inhibition of pancreatic cancer cell growth and enhanced sensitivity to cisplatinum.
Topics: Antineoplastic Agents; Cell Division; Cisplatin; ErbB Receptors; Humans; Pancreatic Neoplasms; Proto-Oncogene Proteins c-fos; RNA, Antisense; Signal Transduction; Tumor Cells, Cultured; Tyrosine | 1996 |
CAS/Crk coupling serves as a "molecular switch" for induction of cell migration.
Topics: Animals; Cell Membrane; Cell Movement; COS Cells; Crk-Associated Substrate Protein; Extracellular Matrix; Gene Expression; GTP-Binding Proteins; Humans; Hypoglycemic Agents; Insulin; Membrane Proteins; Neoplasm Metastasis; Pancreas; Pancreatic Neoplasms; Phosphoproteins; Phosphorylation; Protein Binding; Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-crk; Rabbits; rac GTP-Binding Proteins; ras Proteins; Retinoblastoma-Like Protein p130; src Homology Domains; Tumor Cells, Cultured; Tyrosine | 1998 |
Role of tyrosine phosphorylation in leptin activation of ATP-sensitive K+ channels in the rat insulinoma cell line CRI-G1.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Adenosine Triphosphate; Adenylyl Imidodiphosphate; Androstadienes; Animals; Enzyme Inhibitors; Insulinoma; Leptin; Nitriles; Pancreatic Neoplasms; Phosphoric Monoester Hydrolases; Phosphorylation; Potassium Channels; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Proteins; Rats; Tumor Cells, Cultured; Tyrosine; Tyrphostins; Wortmannin | 1998 |
Src stimulates insulin-like growth factor I (IGF-I)-dependent cell proliferation by increasing IGF-I receptor number in human pancreatic carcinoma cells.
Topics: Cell Division; Humans; Insulin-Like Growth Factor I; Neoplasm Proteins; Pancreatic Neoplasms; Phosphorylation; Proto-Oncogene Proteins pp60(c-src); Receptor, IGF Type 1; Tumor Cells, Cultured; Tyrosine | 1998 |
Association of increased immunostaining for inducible nitric oxide synthase and nitrotyrosine with fibroblast growth factor transformation in pancreatic cancer.
Topics: Adenocarcinoma; Aged; Aged, 80 and over; Fibroblast Growth Factors; Humans; Immunohistochemistry; Nitric Oxide Synthase; Pancreatic Neoplasms; Retrospective Studies; Tyrosine | 1999 |
Protein metabolism in glucagonoma.
Topics: Adult; Amino Acids; Blood Glucose; C-Peptide; Deuterium; Female; Glucagon; Glucagonoma; Humans; Infusions, Intravenous; Insulin; Leucine; Male; Middle Aged; Pancreatic Neoplasms; Phenylalanine; Protein Biosynthesis; Proteins; Reference Values; Tyrosine | 1999 |
Tyrosine nitration of c-SRC tyrosine kinase in human pancreatic ductal adenocarcinoma.
Topics: Adenocarcinoma; Blotting, Western; Chromatography, High Pressure Liquid; Cortactin; Humans; Microfilament Proteins; Nitrates; Pancreatic Neoplasms; Phosphorylation; Phosphotyrosine; Precipitin Tests; Protein Conformation; Protein Folding; Proto-Oncogene Proteins pp60(c-src); Tumor Cells, Cultured; Tyrosine | 2000 |
Inhibition of growth and metastatic progression of pancreatic carcinoma in hamster after somatostatin receptor subtype 2 (sst2) gene expression and administration of cytotoxic somatostatin analog AN-238.
Topics: Animals; Antibiotics, Antineoplastic; Cadherins; Cell Division; Cricetinae; Cytotoxins; Doxorubicin; Fungal Proteins; GTPase-Activating Proteins; Intracellular Signaling Peptides and Proteins; Male; Mesocricetus; Neoplasm Metastasis; Pancreatic Neoplasms; Phosphorylation; Protein Phosphatase 1; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Pyrroles; Saccharomyces cerevisiae Proteins; Tumor Cells, Cultured; Tyrosine | 2000 |
12-lipoxygenase metabolite 12(S)-HETE stimulates human pancreatic cancer cell proliferation via protein tyrosine phosphorylation and ERK activation.
Topics: 12-Hydroxy-5,8,10,14-eicosatetraenoic Acid; Cell Division; DNA; Enzyme Activation; Genistein; Humans; JNK Mitogen-Activated Protein Kinases; Mitogen-Activated Protein Kinases; Pancreatic Neoplasms; Phosphorylation; Tumor Cells, Cultured; Tyrosine | 2001 |
FGF-1 and FGF-2 regulate the expression of E-cadherin and catenins in pancreatic adenocarcinoma.
Topics: Adenocarcinoma; alpha Catenin; beta Catenin; Cadherins; Cell Communication; Cytoskeletal Proteins; Fibroblast Growth Factor 1; Fibroblast Growth Factor 2; Humans; Pancreatic Neoplasms; Phosphorylation; Trans-Activators; Tumor Cells, Cultured; Tyrosine | 2001 |
Letter: Diagnosis of exocrine pancreatic disease by synthetic peptide.
Topics: Adult; Aminobenzoates; Humans; Pancreatic Neoplasms; Pancreatitis; Trypsin; Tyrosine | 1976 |
Diagnosis of pancreatic disease by a synthetic peptide. A new test of exocrine pancreatic function.
Topics: 4-Aminobenzoic Acid; Adenocarcinoma; Adult; Aminobenzoates; Chronic Disease; Dipeptides; Female; Humans; Male; Middle Aged; Pancreas; Pancreatic Neoplasms; Pancreatitis; para-Aminobenzoates; Tyrosine | 1976 |
Effects of epidermal growth factor and analogues of luteinizing hormone-releasing hormone and somatostatin on phosphorylation and dephosphorylation of tyrosine residues of specific protein substrates in various tumors.
Topics: Amino Acid Sequence; Animals; Antineoplastic Agents; Autoradiography; Breast Neoplasms; Cell Line; Colonic Neoplasms; Epidermal Growth Factor; Gonadotropin-Releasing Hormone; Humans; Kinetics; Lung Neoplasms; Membrane Proteins; Molecular Sequence Data; Pancreatic Neoplasms; Phosphorus Radioisotopes; Phosphorylation; Protein Kinases; Protein-Tyrosine Kinases; Somatostatin; Triptorelin Pamoate; Tyrosine | 1991 |
Differential binding and biological activities of epidermal growth factor and transforming growth factor alpha in a human pancreatic cancer cell line.
Topics: Epidermal Growth Factor; ErbB Receptors; Humans; Hydrogen-Ion Concentration; Inositol 1,4,5-Trisphosphate; Iodine Radioisotopes; Pancreatic Neoplasms; Phosphorylation; Statistics as Topic; Transforming Growth Factor alpha; Tumor Cells, Cultured; Tyrosine | 1991 |
Somatostatin receptor imaging with 123I-Tyr3-Octreotide.
Topics: Autoradiography; Brain Neoplasms; Breast Neoplasms; Humans; Iodine Radioisotopes; Multiple Endocrine Neoplasia; Octreotide; Pancreatic Neoplasms; Radiography; Radionuclide Imaging; Receptors, Neurotransmitter; Receptors, Somatostatin; Somatostatin; Tyrosine | 1990 |
Reduced tyrosine phosphorylation and nonresponsiveness to EGF-mediated cytotoxicity in EGF receptor-hyperproducing UCVA-1 cells.
Topics: Carcinoma, Squamous Cell; Cell Division; Down-Regulation; Epidermal Growth Factor; ErbB Receptors; Humans; Pancreatic Neoplasms; Peptide Mapping; Phosphatidylinositols; Phosphoproteins; Phosphorylation; Protein-Tyrosine Kinases; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tyrosine | 1990 |
The genesis of apudamyloid in endocrine polypeptide tumours: histochemical distinction from immunamyloid.
Topics: Adenocarcinoma, Scirrhous; Adenoma, Islet Cell; Adrenal Gland Neoplasms; Amyloidosis; Arthritis, Rheumatoid; Carcinoma; Endocrine System Diseases; Histocytochemistry; Humans; Microscopy, Electron; Neoplasm Proteins; Neoplasms; Pancreatic Neoplasms; Pheochromocytoma; Thyroid Neoplasms; Tryptophan Oxygenase; Tyrosine | 1972 |
Fibrinaemia and multiple thrombi in pancreatic carcinoma. A case studied with quantitative N-terminal analysis.
Topics: Alanine; Blood Coagulation; Blood Coagulation Tests; Disseminated Intravascular Coagulation; Fibrin; Fibrinogen; Glycine; Heparin; Humans; Male; Methods; Middle Aged; Pancreatic Neoplasms; Thrombin; Thrombophlebitis; Tyrosine; Warfarin | 1972 |
[The effect of thyroid hormone on tumor cells in a tissue culture].
Topics: Animals; Culture Techniques; Diiodotyrosine; Embryo, Mammalian; Female; Humans; Mitosis; Ovarian Neoplasms; Pancreatic Neoplasms; Pregnancy; Rabbits; Thyroid Hormones; Tyrosine | 1968 |