tyrosine has been researched along with Basophilic Leukemia, Acute in 47 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 36 (76.60) | 18.2507 |
| 2000's | 9 (19.15) | 29.6817 |
| 2010's | 2 (4.26) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hao, Y; Piao, X | 1 |
| Barua, D; Goldstein, B | 1 |
| Kyo, S; Maeno, K; Miah, SM; Qu, X; Sada, K; Yamamura, H | 1 |
| Matsui, T; Ra, C; Suzuki, Y; Yoshimaru, T | 1 |
| Kawauchi-Kamata, K; Kyo, S; Maeno, K; Miah, SM; Qu, X; Sada, K; Yamamura, H | 1 |
| Honda, S; Kojima, H; Miyamoto, A; Nagasawa, T; Nakahashi, C; Okoshi, Y; Shibuya, A; Shibuya, K; Tahara-Hanaoka, S | 1 |
| Brothers, EA; Chichester, K; Gibbons, SP; Kim, SC; MacDonald, SM; Rotté, MJ; Vonakis, BM | 1 |
| Hirashima, N; Kato, N; Nakanishi, M | 1 |
| Hanashiro, K; Kosugi, T; Nakamura, M; Nakasone, T; Sunagawa, M | 1 |
| Furuno, T; Ikebuchi, H; Nakanishi, M; Sawada, J; Terao, T; Teshima, R | 1 |
| Hagmann, W | 1 |
| Benhamou, M; Kawakami, T; Kawakami, Y; Minoguchi, K; Siraganian, RP; Swaim, WD | 1 |
| Ikebuchi, H; Nakanishi, M; Sawada, J; Teshima, R | 1 |
| Mao, SY; Metzger, H; Yamashita, T | 1 |
| Brugge, JS; Rivera, VM | 1 |
| Goldstein, B; Kent, UM; Mao, SY; Metzger, H; Wofsy, C | 1 |
| Berenstein, EH; Siraganian, RP; Swaim, WD; Swieter, M | 1 |
| Blumberg, PM; Chang, EY; Haleem-Smith, H; Rivera, J; Szallasi, Z | 1 |
| Anderson, WB; Blumberg, PM; Chang, EY; Denning, MF; Lehel, C; Olah, Z; Rivera, J; Szallasi, Z; Yuspa, SH | 1 |
| Arai, T; Matsui, K; Miyamoto, H | 1 |
| Kumada, T; Miyata, H; Nozawa, Y | 1 |
| Beaven, MA; Santini, F | 1 |
| Fujimiya, H; Kato, Y; Kumada, T; Miyata, H; Nakamura, Y; Nakashima, S; Nozawa, Y | 1 |
| Bombien, E; Jones, SV; Offermanns, S; Schultz, G | 1 |
| Beaven, MA; Hirasawa, N; Rider, LG; Santini, F | 1 |
| Matsui, K; Miyamoto, H | 1 |
| Atkinson, TP; Yang, Q | 1 |
| Choe, YK; Han, MY; Koh, WS; Park, YM; Yoon, SY | 1 |
| Fischler, C; Hamawy, MM; Siraganian, RP; Zhang, J | 1 |
| Baird, B; Goldstein, B; Holowka, D; Xu, K | 1 |
| Aktories, K; Barth, H; Prepens, U; Wilting, J | 1 |
| Goldstein, B; Kent, UM; Metzger, H; Torigoe, C; Wofsy, C | 1 |
| de Mol, NJ; Fischer, MJ; Janssen, LH; Paulussen, JJ; Roozendaal, RL; van der Heijden, VC; van Dijken, P | 1 |
| Honda, Z; Nada, S; Okada, M; Shoji, S; Suzuki, T; Yamamoto, K; Yamamoto, T | 1 |
| Pecht, I; Seger, R; Xu, R | 1 |
| Siraganian, RP; Zhang, J | 1 |
| Dráber, P; Dráberová, E; Dráberová, L; Surviladze, Z | 1 |
| Murakami, K; Nagasawa, S; Sato, S; Yamashita, T | 1 |
| Hayakawa, S; Matsui, T; Shimizu, K; Suzuki, Y; Suzuki-Karasaki, M; Yamaki, M; Yamashita, K; Yoshimaru, T | 1 |
| Atkinson, TP; Hohman, RJ; Kaliner, MA | 1 |
| Benhamou, M; Gutkind, JS; Robbins, KC; Siraganian, RP; Stephan, V | 1 |
| Benhamou, M; Robbins, KC; Siraganian, RP; Stephan, V | 1 |
| Bolen, JB; Eiseman, E | 1 |
| Deanin, GG; Li, W; Margolis, B; Oliver, JM; Schlessinger, J | 1 |
| Min, HK; Park, DJ; Rhee, SG | 1 |
| Conklyn, MJ; Connelly, PA; Farrell, CA; Merenda, JM; Showell, HJ | 1 |
| Haimovich, J; Jariwala, N; Lyall, R; Yu, KT; Zilberstein, A | 1 |
47 other study(ies) available for tyrosine and Basophilic Leukemia, Acute
| Article | Year |
|---|---|
Saikosaponin-d inhibits β-conglycinin induced activation of rat basophilic leukemia-2H3 cells.
Topics: Animals; Anti-Allergic Agents; Antigens, Plant; beta-N-Acetylhexosaminidases; Calcium Signaling; Cell Degranulation; Cell Line, Tumor; Food Hypersensitivity; Globulins; Glycine max; Humans; Immunoglobulin E; Leukemia, Basophilic, Acute; Mast Cells; Medicine, Chinese Traditional; Oleanolic Acid; Phosphorylation; Rats; Reactive Oxygen Species; Saponins; Seed Storage Proteins; Signal Transduction; Soybean Proteins; Tyrosine | 2012 |
A mechanistic model of early FcεRI signaling: lipid rafts and the question of protection from dephosphorylation.
Topics: Animals; Calcium; Cell Membrane; Computer Simulation; Haptens; Immunoglobulin E; Intracellular Signaling Peptides and Proteins; Leukemia, Basophilic, Acute; Lipoylation; Mast Cells; Membrane Microdomains; Models, Biological; Mutation; Phosphorylation; Protein-Tyrosine Kinases; Rats; Receptors, IgE; Signal Transduction; src-Family Kinases; Syk Kinase; Tumor Cells, Cultured; Tyrosine | 2012 |
Regulation of FcepsilonRI-mediated degranulation by an adaptor protein 3BP2 in rat basophilic leukemia RBL-2H3 cells.
Topics: Animals; Antigens, CD; Carrier Proteins; Cell Degranulation; Isoenzymes; Leukemia, Basophilic, Acute; MAP Kinase Signaling System; Membrane Proteins; Phospholipase C gamma; Phosphorylation; Rats; Receptors, Fc; Receptors, IgE; Signal Transduction; src Homology Domains; Transfection; Tumor Cells, Cultured; Type C Phospholipases; Tyrosine | 2002 |
Silver activates calcium signals in rat basophilic leukemia-2H3 mast cells by a mechanism that differs from the Fc epsilon RI-activated response.
Topics: Animals; Calcium; Calcium Signaling; Carrier Proteins; Cell Degranulation; Enzyme Precursors; Immunity, Innate; Interleukin-4; Intracellular Signaling Peptides and Proteins; Isoenzymes; Leukemia, Basophilic, Acute; Leukotriene C4; Mast Cells; Mitogen-Activated Protein Kinases; Phospholipase C gamma; Phosphoproteins; Protein-Tyrosine Kinases; Rats; Receptors, IgE; Silver; Silver Nitrate; src-Family Kinases; Syk Kinase; Thapsigargin; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Type C Phospholipases; Tyrosine | 2002 |
Negative regulation of Lyn protein-tyrosine kinase by c-Cbl ubiquitin-protein ligase in Fc epsilon RI-mediated mast cell activation.
Topics: Animals; beta-N-Acetylhexosaminidases; Cell Line, Tumor; Chlorocebus aethiops; COS Cells; Enzyme Activation; Gene Expression Regulation; Leukemia, Basophilic, Acute; Mast Cells; Phosphorylation; Precipitin Tests; Proto-Oncogene Proteins; Rats; Receptors, IgE; src-Family Kinases; Tyrosine; Ubiquitin | 2003 |
Requirement of the tyrosines at residues 258 and 270 of MAIR-I in inhibitory effect on degranulation from basophilic leukemia RBL-2H3.
Topics: Amino Acid Substitution; Animals; Antibodies, Monoclonal; Basophils; Cell Degranulation; Cell Line, Tumor; Immunoglobulin E; Leukemia, Basophilic, Acute; Mast Cells; Mutation; Phosphorylation; Protein Tyrosine Phosphatases; Rats; Receptors, IgE; Receptors, Polymeric Immunoglobulin; Tyrosine | 2005 |
Regulation of rat basophilic leukemia-2H3 mast cell secretion by a constitutive Lyn kinase interaction with the high affinity IgE receptor (Fc epsilon RI).
Topics: Adaptor Proteins, Signal Transducing; Animals; Calcium; Cell Line, Tumor; Cell Membrane; Enzyme Precursors; Histamine; Intracellular Signaling Peptides and Proteins; Kinetics; Leukemia, Basophilic, Acute; Mast Cells; Mice; Phosphoproteins; Phosphorylation; Protein Structure, Tertiary; Protein-Tyrosine Kinases; Rats; Receptors, IgE; Signal Transduction; src-Family Kinases; Syk Kinase; Transfection; Tumor Necrosis Factor-alpha; Tyrosine | 2005 |
Flotillin-1 regulates IgE receptor-mediated signaling in rat basophilic leukemia (RBL-2H3) cells.
Topics: Animals; Calcium; Calcium Signaling; Cell Degranulation; Cell Line, Tumor; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Leukemia, Basophilic, Acute; Mast Cells; Membrane Microdomains; Membrane Proteins; Phosphorylation; Rats; Receptors, IgE; Signal Transduction; src-Family Kinases; Transfection; Tyrosine | 2006 |
Inhibition of IgE-mediated phosphorylation of FcepsilonRIgamma protein by antiallergic drugs in rat basophilic leukemia (RBL-2H3) cells: a novel action of antiallergic drugs.
Topics: Animals; Anti-Allergic Agents; Dibenzazepines; Down-Regulation; Imidazoles; Immunoglobulin E; Immunoprecipitation; Leukemia, Basophilic, Acute; Mast Cells; Phosphorylation; Phthalazines; Protein Binding; Rats; Receptors, IgE; Signal Transduction; Tumor Cells, Cultured; Tyrosine | 2007 |
Effects of herbimycin A and ST638 on Fc epsilon receptor-mediated histamine release and Ca2+ signals in rat basophilic leukemia (RBL-2H3) cells.
Topics: Animals; Antibodies, Monoclonal; Benzoquinones; Calcium; Cell Line; Cinnamates; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Fura-2; Histamine Release; Inositol 1,4,5-Trisphosphate; Kinetics; Lactams, Macrocyclic; Leukemia, Basophilic, Acute; Molecular Weight; Phosphoproteins; Phosphotyrosine; Protein-Tyrosine Kinases; Quinones; Rats; Receptors, IgG; Rifabutin; Sulfides; Tumor Cells, Cultured; Tyrosine | 1994 |
Cell proliferation status, cytokine action and protein tyrosine phosphorylation modulate leukotriene biosynthesis in a basophil leukaemia and a mastocytoma cell line.
Topics: Animals; Benzoquinones; Catechols; Cell Division; Cell Line; Genistein; Interleukin-3; Interleukin-4; Ionomycin; Isoflavones; Kinetics; Lactams, Macrocyclic; Leukemia, Basophilic, Acute; Leukotrienes; Mast-Cell Sarcoma; Mice; Nitriles; Phosphoproteins; Phosphotyrosine; Protein-Tyrosine Kinases; Quinones; Rats; Rifabutin; Tumor Cells, Cultured; Tyrosine; Tyrphostins | 1994 |
Activation of protein tyrosine kinase p72syk by Fc epsilon RI aggregation in rat basophilic leukemia cells. p72syk is a minor component but the major protein tyrosine kinase of pp72.
Topics: Amino Acid Sequence; Animals; Antibodies; Cell Line; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Enzyme Precursors; Immunoblotting; Intracellular Signaling Peptides and Proteins; Leukemia, Basophilic, Acute; Molecular Sequence Data; Molecular Weight; Peptides; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Rabbits; Rats; Receptors, IgE; Syk Kinase; Tumor Cells, Cultured; Tyrosine | 1994 |
Stimulatory effect of pervanadate on calcium signals and histamine secretion of RBL-2H3 cells.
Topics: Animals; Calcium; Catalase; Histamine Release; Hydrogen Peroxide; Inositol 1,4,5-Trisphosphate; Leukemia, Basophilic, Acute; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Rats; Signal Transduction; Tumor Cells, Cultured; Tyrosine; Vanadates | 1994 |
Chemical cross-linking of IgE-receptor complexes in RBL-2H3 cells.
Topics: Animals; Blotting, Western; Cell Membrane Permeability; Cross-Linking Reagents; Electrophoresis, Polyacrylamide Gel; Immunoglobulin E; Immunosorbent Techniques; Leukemia, Basophilic, Acute; Macromolecular Substances; Mast Cells; Phosphorylation; Phosphotyrosine; Rats; Receptors, IgE; Succinimides; Tumor Cells, Cultured; Tyrosine | 1995 |
Clustering of Syk is sufficient to induce tyrosine phosphorylation and release of allergic mediators from rat basophilic leukemia cells.
Topics: Animals; Cell Line; Cell Membrane; Cytokines; Enzyme Precursors; Genetic Vectors; Humans; Interleukins; Intracellular Signaling Peptides and Proteins; Leukemia, Basophilic, Acute; Leukotrienes; Mast Cells; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Rats; Receptors, IgE; Recombinant Fusion Proteins; Syk Kinase; Tumor Cells, Cultured; Tyrosine; Vaccinia virus | 1995 |
Kinetics of tyrosine phosphorylation when IgE dimers bind to FC epsilon receptors on rat basophilic leukemia cells.
Topics: Animals; Antibodies, Monoclonal; Cell Line; Immunoglobulin E; Leukemia, Basophilic, Acute; Macromolecular Substances; Mathematics; Mice; Models, Structural; Models, Theoretical; Phosphorylation; Phosphotyrosine; Rabbits; Rats; Receptors, IgE; Tumor Cells, Cultured; Tyrosine | 1995 |
Aggregation of IgE receptors in rat basophilic leukemia 2H3 cells induces tyrosine phosphorylation of the cytosolic protein-tyrosine phosphatase HePTP.
Topics: Amino Acid Sequence; Animals; Base Sequence; Blotting, Northern; Brain; Calcimycin; Calcium; Cell Line; Cloning, Molecular; Cytosol; DNA Primers; Gene Expression; Immunoblotting; Intracellular Signaling Peptides and Proteins; Leukemia, Basophilic, Acute; Mice; Molecular Sequence Data; Organ Specificity; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatase, Non-Receptor Type 6; Protein Tyrosine Phosphatases; Protein Tyrosine Phosphatases, Non-Receptor; Rats; Receptors, IgE; RNA, Messenger; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tyrosine | 1995 |
Tyrosine phosphorylation of protein kinase C-delta in response to the activation of the high-affinity receptor for immunoglobulin E modifies its substrate recognition.
Topics: Animals; Antigens; Cell Line; Cell Membrane; Immunoglobulin E; Isoenzymes; Kinetics; Leukemia, Basophilic, Acute; Phosphorylation; Phosphotyrosine; Protein Kinase C; Rats; Receptors, IgE; Signal Transduction; Substrate Specificity; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured; Tyrosine | 1995 |
Development of a rapid approach to identification of tyrosine phosphorylation sites: application to PKC delta phosphorylated upon activation of the high affinity receptor for IgE in rat basophilic leukemia cells.
Topics: Amino Acid Sequence; Animals; Cell Line; Isoenzymes; Leukemia, Basophilic, Acute; Molecular Sequence Data; Oligopeptides; Phosphorylation; Phosphotyrosine; Protein Kinase C; Rats; Receptors, IgE; src-Family Kinases; Substrate Specificity; Tumor Cells, Cultured; Tyrosine | 1995 |
The effect of a naphthalene derivative, TEI-6472, on histamine release and tyrosine phosphorylation in rat basophilic leukemia cells.
Topics: Animals; Basophils; Cinnamates; Dinitrophenols; Haptens; Histamine Release; Immunoblotting; Immunoglobulin E; Immunosuppressive Agents; Leukemia, Basophilic, Acute; Naphthalenes; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein Kinase C; Protein-Tyrosine Kinases; Rats; Receptors, IgE; Serum Albumin; Signal Transduction; Sulfides; Time Factors; Tumor Cells, Cultured; Tyrosine | 1995 |
Involvement of tyrosine phosphorylation in IgE receptor-mediated phospholipase D activation in rat basophilic leukemia (RBL-2H3) cells.
Topics: Animals; Antigens; Basophils; Cinnamates; Enzyme Activation; Genistein; Immunoglobulin E; In Vitro Techniques; Isoflavones; Leukemia, Basophilic, Acute; Phospholipase D; Phosphorylation; Phosphotyrosine; Protein Kinase C; Protein-Tyrosine Kinases; Rats; Receptors, IgE; Signal Transduction; Sulfides; Tumor Cells, Cultured; Tyrosine | 1993 |
Tyrosine phosphorylation of a mitogen-activated protein kinase-like protein occurs at a late step in exocytosis. Studies with tyrosine phosphatase inhibitors and various secretagogues in rat RBL-2H3 cells.
Topics: Actins; Animals; Arachidonic Acid; Calcimycin; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Carbachol; Cell Line; Electrophoresis, Polyacrylamide Gel; Exocytosis; Hexosaminidases; Hydrogen Peroxide; Inositol Phosphates; Kinetics; Leukemia, Basophilic, Acute; Phospholipids; Phosphoproteins; Phosphorylation; Phosphotyrosine; Protein Tyrosine Phosphatases; Rats; Tumor Cells, Cultured; Tyrosine; Vanadates | 1993 |
Effects of an antiallergic drug, pemirolast potassium on tyrosine phosphorylation and map kinase activation in antigen-stimulated rat basophilic leukemia (RBL-2H3) cells.
Topics: Animals; Antigens; Calcium-Calmodulin-Dependent Protein Kinases; Enzyme Activation; Histamine Antagonists; Leukemia, Basophilic, Acute; Phosphorylation; Pyridines; Pyrimidinones; Rats; Tumor Cells, Cultured; Tyrosine | 1995 |
Stimulation of mitogen-activated protein kinase activity by different secretory stimuli in rat basophilic leukemia cells.
Topics: Animals; Calcimycin; Calcium-Calmodulin-Dependent Protein Kinases; Cell Degranulation; Enzyme Activation; Leukemia, Basophilic, Acute; Mitogen-Activated Protein Kinase 1; Mitogens; Molecular Weight; Phosphorylation; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Rats; Receptors, IgE; Serotonin; Signal Transduction; Tumor Cells, Cultured; Tyrosine | 1994 |
Activation of the mitogen-activated protein kinase cascade is suppressed by low concentrations of dexamethasone in mast cells.
Topics: Animals; Antigens; Arachidonic Acids; Calcium-Calmodulin-Dependent Protein Kinases; Dexamethasone; Dose-Response Relationship, Immunologic; Enzyme Activation; Immunosuppressive Agents; Leukemia, Basophilic, Acute; MAP Kinase Kinase 1; Mast Cells; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase Kinases; Phospholipases A; Phospholipases A2; Phosphorylation; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-raf; Rats; Receptors, IgE; src-Family Kinases; Thapsigargin; Tumor Cells, Cultured; Tyrosine | 1996 |
The characterization of tyrosine phosphorylation of 78 and 92 kDa proteins in rat basophilic RBL-2H3 cells.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Cells, Cultured; Cinnamates; Histamine Release; Leukemia, Basophilic, Acute; Molecular Weight; Naphthalenes; Phosphorylation; Protein Kinase C; Proteins; Rats; Receptors, IgE; Sulfides; Tyrosine | 1996 |
Translocation of phospholipase C-gamma 2 induced by in vitro activation of protein tyrosine kinase activity in mast cell lysates.
Topics: Adenosine Triphosphate; Animals; Biological Transport; Cations, Divalent; Cell Membrane; Enzyme Activation; Enzyme Inhibitors; Genistein; Isoenzymes; Isoflavones; Leukemia, Basophilic, Acute; Magnesium; Manganese; Mast Cells; Phospholipase C gamma; Phosphorylation; Protein-Tyrosine Kinases; Rats; Sonication; Tumor Cells, Cultured; Type C Phospholipases; Tyrosine; Vanadates | 1996 |
Fc epsilon RI-ligation induces association of tyrosine phosphorylated proteins with Src homology 2 domains of phospholipase C gamma 1 in RBL-2H3 rat basophilic leukemia cells.
Topics: Animals; Antibodies; Antibody Specificity; Binding Sites; Dinitrophenols; Immunoglobulin E; Isoenzymes; Leukemia, Basophilic, Acute; Neoplasm Proteins; Phospholipase C gamma; Phosphorylation; Protein-Tyrosine Kinases; Rats; Receptors, IgE; Serum Albumin, Bovine; Signal Transduction; src Homology Domains; Stimulation, Chemical; Tumor Cells, Cultured; Type C Phospholipases; Tyrosine | 1997 |
Fc epsilon RI aggregation induces tyrosine phosphorylation of a novel 72 kDa protein downstream of Syk.
Topics: Animals; Antibodies, Monoclonal; Antibody Specificity; Antigen-Antibody Complex; Enzyme Precursors; Intracellular Signaling Peptides and Proteins; Leukemia, Basophilic, Acute; Mice; Mice, Inbred BALB C; Molecular Weight; Phosphoproteins; Phosphorylation; Protein-Tyrosine Kinases; Rats; Receptor Aggregation; Receptors, IgE; Signal Transduction; Syk Kinase; Tumor Cells, Cultured; Tyrosine | 1997 |
Kinetics of multivalent antigen DNP-BSA binding to IgE-Fc epsilon RI in relationship to the stimulated tyrosine phosphorylation of Fc epsilon RI.
Topics: Animals; Cattle; Cross-Linking Reagents; Dinitrophenols; Fluorescein-5-isothiocyanate; Haptens; Immunoglobulin E; Kinetics; Leukemia, Basophilic, Acute; Ligands; Models, Immunological; Phosphorylation; Protein Binding; Rats; Receptors, IgE; Serum Albumin, Bovine; Spectrometry, Fluorescence; Time Factors; Tumor Cells, Cultured; Tyrosine | 1998 |
Influence of Clostridium botulinum C2 toxin on Fc epsilonRI-mediated secretion and tyrosine phosphorylation in RBL cells.
Topics: Actins; Animals; Botulinum Toxins; Dose-Response Relationship, Drug; Leukemia, Basophilic, Acute; Phosphorylation; Rats; Receptors, IgE; Serotonin; Tumor Cells, Cultured; Tyrosine | 1998 |
Exploiting the difference between intrinsic and extrinsic kinases: implications for regulation of signaling by immunoreceptors.
Topics: Animals; Enzyme Activation; Kinetics; Leukemia, Basophilic, Acute; Models, Immunological; Phosphorylation; Rats; Receptor Protein-Tyrosine Kinases; Receptors, Immunologic; Signal Transduction; src-Family Kinases; Tumor Cells, Cultured; Tyrosine | 1997 |
Effects of oxatomide and derivatives on high affinity IgE receptor-activated signal transduction pathways in rat basophilic leukemia cells: role of protein tyrosine hyperphosphorylation and inhibition of extracellular calcium influx.
Topics: Animals; Anti-Allergic Agents; Calcium; Calcium Radioisotopes; Cell Adhesion; Enzyme Inhibitors; Exocytosis; Extracellular Space; Fibronectins; Inositol 1,4,5-Trisphosphate; Leukemia, Basophilic, Acute; Neoplasm Proteins; Phosphorylation; Piperazines; Rats; Receptors, IgE; Signal Transduction; Thapsigargin; Tumor Cells, Cultured; Tyrosine | 1998 |
Essential roles of Lyn in fibronectin-mediated filamentous actin assembly and cell motility in mast cells.
Topics: Actins; Amino Acid Sequence; Animals; Cell Adhesion; Cell Movement; CSK Tyrosine-Protein Kinase; Fibronectins; Humans; Leukemia, Basophilic, Acute; Mast Cells; Membrane Proteins; Molecular Sequence Data; Phosphorylation; Protein-Tyrosine Kinases; Rats; src-Family Kinases; Tumor Cells, Cultured; Tyrosine | 1998 |
Cutting edge: extracellular signal-regulated kinase activates syk: a new potential feedback regulation of Fc epsilon receptor signaling.
Topics: Animals; Antigens; Calcium-Calmodulin-Dependent Protein Kinases; Cell Degranulation; Enzyme Activation; Enzyme Inhibitors; Enzyme Precursors; Feedback; Intracellular Signaling Peptides and Proteins; Leukemia, Basophilic, Acute; MAP Kinase Kinase Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Phosphorylation; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Rats; Receptors, IgE; Recombinant Proteins; Signal Transduction; Subcellular Fractions; Syk Kinase; Tumor Cells, Cultured; Tyrosine | 1999 |
CD45 is essential for Fc epsilon RI signaling by ZAP70, but not Syk, in Syk-negative mast cells.
Topics: Animals; Cell Degranulation; Enzyme Precursors; Intracellular Signaling Peptides and Proteins; Leukemia, Basophilic, Acute; Leukocyte Common Antigens; Lymphocyte Activation; Mast Cells; Phosphorylation; Protein Binding; Protein-Tyrosine Kinases; Rats; Receptors, IgE; Receptors, Immunologic; Signal Transduction; Syk Kinase; Transfection; Tumor Cells, Cultured; Tyrosine; ZAP-70 Protein-Tyrosine Kinase | 1999 |
Protein tyrosine kinase p53/p56(lyn) forms complexes with gamma-tubulin in rat basophilic leukemia cells.
Topics: Animals; Antibodies, Monoclonal; Basophils; Centrifugation, Density Gradient; Fluorescent Antibody Technique; Leukemia, Basophilic, Acute; Lymphocyte Activation; Phosphorylation; Rats; src-Family Kinases; Tubulin; Tumor Cells, Cultured; Tyrosine | 1999 |
Regulation of mast cell signaling through high-affinity IgE receptor by CD45 protein tyrosine phosphatase.
Topics: Animals; Calcium; Flow Cytometry; Gene Expression Regulation; Leukemia, Basophilic, Acute; Leukocyte Common Antigens; Mast Cells; Phosphorylation; Rats; Receptors, IgE; Signal Transduction; src-Family Kinases; Tumor Cells, Cultured; Tyrosine | 2000 |
Epigallocatechin gallate inhibits histamine release from rat basophilic leukemia (RBL-2H3) cells: role of tyrosine phosphorylation pathway.
Topics: Animals; Antineoplastic Agents; Catechin; Histamine Release; Leukemia, Basophilic, Acute; Leukemia, Experimental; Mast Cells; Phosphorylation; Rats; Signal Transduction; Tumor Cells, Cultured; Tyrosine | 2000 |
Phospholipase C-gamma 1 is translocated to the membrane of rat basophilic leukemia cells in response to aggregation of IgE receptors.
Topics: Animals; Antigens, Differentiation, B-Lymphocyte; Biological Transport; Cell Membrane; Cytosol; Enzyme Activation; Immunoglobulin E; Leukemia, Basophilic, Acute; Mice; Phosphatidylinositols; Phosphorylation; Rabbits; Rats; Receptors, Fc; Receptors, IgE; Temperature; Type C Phospholipases; Tyrosine | 1992 |
Fc epsilon RI-induced protein tyrosine phosphorylation of pp72 in rat basophilic leukemia cells (RBL-2H3). Evidence for a novel signal transduction pathway unrelated to G protein activation and phosphatidylinositol hydrolysis.
Topics: 3T3 Cells; Animals; Antigens, Differentiation, B-Lymphocyte; Carbachol; Cell Line; Genistein; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Immunoglobulin E; Inositol Phosphates; Isoflavones; Kinetics; Leukemia, Basophilic, Acute; Mice; Models, Biological; Phosphatidylinositols; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Rats; Receptors, Fc; Receptors, IgE; Receptors, Muscarinic; Signal Transduction; Transfection; Type C Phospholipases; Tyrosine | 1992 |
High-affinity IgE receptor-mediated stimulation of rat basophilic leukemia (RBL-2H3) cells induces early and late protein-tyrosine phosphorylations.
Topics: Animals; Antigens, Differentiation, B-Lymphocyte; Basophils; Biological Transport; Blotting, Western; Calcimycin; Calcium; Electrophoresis, Polyacrylamide Gel; Genistein; Histamine Release; Immunoglobulin E; Isoflavones; Leukemia, Basophilic, Acute; Mast Cells; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Proteins; Rats; Receptors, Fc; Receptors, IgE; Signal Transduction; Tumor Cells, Cultured; Tyrosine | 1992 |
Signal transduction by the cytoplasmic domains of Fc epsilon RI-gamma and TCR-zeta in rat basophilic leukemia cells.
Topics: Animals; Antibodies, Monoclonal; Cell Membrane; Kinetics; Leukemia, Basophilic, Acute; Macromolecular Substances; Phosphotyrosine; Proto-Oncogene Proteins pp60(c-src); Rats; Receptors, Antigen, T-Cell; Receptors, IgE; Recombinant Fusion Proteins; Serotonin; Signal Transduction; Transfection; Tumor Cells, Cultured; Tyrosine | 1992 |
Fc epsilon R1-mediated tyrosine phosphorylation of multiple proteins, including phospholipase C gamma 1 and the receptor beta gamma 2 complex, in RBL-2H3 rat basophilic leukemia cells.
Topics: Animals; Antigens, Differentiation, B-Lymphocyte; Cross-Linking Reagents; Enzyme Activation; Leukemia, Basophilic, Acute; Mast Cells; Phosphoproteins; Phosphorylation; Rats; Receptors, Fc; Receptors, IgE; Signal Transduction; Tumor Cells, Cultured; Type C Phospholipases; Tyrosine | 1992 |
IgE-induced tyrosine phosphorylation of phospholipase C-gamma 1 in rat basophilic leukemia cells.
Topics: Animals; Benzoquinones; Blotting, Western; Enzyme Activation; Immunoglobulin E; Isoenzymes; Lactams, Macrocyclic; Leukemia, Basophilic, Acute; Phosphorylation; Phosphotransferases; Phosphotransferases (Alcohol Group Acceptor); Precipitin Tests; Quinones; Rats; Rifabutin; Tumor Cells, Cultured; Type C Phospholipases; Tyrosine | 1991 |
Tyrosine phosphorylation is an early signaling event common to Fc receptor crosslinking in human neutrophils and rat basophilic leukemia cells (RBL-2H3).
Topics: Animals; Antigens, Differentiation, B-Lymphocyte; Cell Line; Complement C5a; Cross-Linking Reagents; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; In Vitro Techniques; Ionomycin; Kinetics; Leukemia, Basophilic, Acute; Neutrophils; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Rats; Receptors, Fc; Receptors, IgE; Signal Transduction; Tetradecanoylphorbol Acetate; Tyrosine | 1991 |
Antigen- and ionophore-induced signal transduction in rat basophilic leukemia cells involves protein tyrosine phosphorylation.
Topics: Animals; Antigens; Antigens, Differentiation, B-Lymphocyte; Calcimycin; Calcium; Catechols; Cell Line; Dinitrophenols; Immunoblotting; Immunoglobulin E; Kinetics; Leukemia, Basophilic, Acute; Magnesium; Nitriles; Peptide Mapping; Phosphopeptides; Phosphoproteins; Phosphorylation; Protein-Tyrosine Kinases; Rats; Receptors, Fc; Receptors, IgE; Serotonin; Serum Albumin, Bovine; Signal Transduction; Tyrosine; Tyrphostins | 1991 |