tyrosine has been researched along with Arteriosclerosis in 78 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 8 (10.26) | 18.7374 |
1990's | 25 (32.05) | 18.2507 |
2000's | 45 (57.69) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Heinecke, JW | 3 |
Ballinger, SW; Burow, DL; Conklin, CA; Horaist, C; Hu, Z; Hunter, GC; Knight-Lozano, CA; Lebovitz, R; McIntyre, K; Patterson, C; Reuf, J; Runge, MS | 1 |
Chade, AR; Grande, JP; Krier, JD; Lerman, A; Lerman, LO; Napoli, C; Rodriguez-Porcel, M; Romero, JC | 1 |
Brinkman, WT; Chaikof, EL; Najibi, S; Terramani, TT | 1 |
d'Uscio, LV; Katusic, ZS; Milstien, S; Richardson, D; Smith, L | 1 |
Astern, J; Chen, J; Huang, PL; Ichinose, H; Kuhlencordt, P; Urano, F | 1 |
Atik, U; Aytacoglu, B; Dikmengil, M; Ercan, B; Sucu, N; Tamer, L; Unlü, A | 1 |
Abdalla, DS; Aldrighi, JM; Bertolami, MC; Campos, MF; Faludi, AA; Ferderbar, S; Lima, ES; Pereira, IR | 1 |
Agellon, LB; Francis, GA; Macdonald, DL; Nation, PN; Terry, TL | 1 |
Aviles, RJ; Brennan, ML; Fu, X; Hazen, SL; Penn, MS; Shishehbor, MH; Sprecher, DL | 1 |
Furuhashi, M; Higashiura, K; Hyakukoku, M; Murakami, H; Shimamoto, K; Ura, N; Yamaguchi, K | 1 |
Brennan, ML; Hazen, SL | 1 |
Hashimoto, N; Horiuchi, S; Makino, H; Saito, Y; Sano, H; Seki, N; Yagui, K | 1 |
El Khoury, JB; Hatters, DM; Howlett, GJ; Khan, T; Lopez, R; Medeiros, LA; Moore, KJ; O'Brien, KD; Pham, CL | 1 |
Fisher, MT; Khor, HK; Schöneich, C | 1 |
Cameron, AJ; Hillyard, DZ; Jardine, AG; McDonald, KJ | 1 |
Bentley, MD; Caplice, N; Chade, AR; Lerman, A; Lerman, LO; Napoli, C; Ritman, EL; Rodriguez-Porcel, M; Sica, V; Zhu, XY | 1 |
Ling, W; Ma, J; Xia, M; Zhang, R; Zhu, H | 1 |
Bergt, C; Brunzell, J; Byun, J; Chait, A; Geary, RL; Green, PS; Heinecke, JW; Kassim, SY; McDonald, TO; O'brien, K; Oram, JF; Pennathur, S; Shao, B; Singh, P | 1 |
Brennan, ML; Fox, PL; Fu, X; Goormastic, M; Hazen, SL; Ischiropoulos, H; Kinter, M; Nukuna, B; Schmitt, D; Settle, M; Smith, JD; Sun, M; Thomson, L; Zheng, L | 1 |
Anantharamaiah, GM; Bergt, C; Brunzell, J; Byun, J; Chait, A; Fu, X; Geary, RL; Heinecke, JW; McDonald, TO; O'Brien, K; Oram, JF; Pennathur, S; Singh, P | 1 |
Beall, HD; Brooks, DM; Bunderson, M; Coffin, JD; Rosenfeld, ME; Walker, DL | 1 |
Ballinger, SW; Ischiropoulos, H; Knight, CA; Madamanchi, NR; Runge, MS; Vickers, KC; Westbrook, D; Young, CG | 1 |
Descamps-Latscha, B; Drüeke, TB; Ivanovski, O; Lacour, B; Massy, ZA; Nguyen-Khoa, T; Phan, O; Ruellan, N; Szumilak, D | 1 |
Ferns, GA; Hourani, SM; Lamb, DJ; Tickner, ML | 1 |
Fontana, P | 1 |
Baromedov, MM | 1 |
Miller, YI; Shaklai, N | 1 |
Buttery, LD; Chester, AH; Evans, TJ; Parums, DV; Polak, JM; Springall, DR; Standfield, EN; Yacoub, MH | 1 |
Evans, P; Halliwell, B; Kaur, H; Mitchinson, MJ | 1 |
Hardy, MM; Hazen, SL; Heinecke, JW; Leeuwenburgh, C; Oh-ishi, S; Steinbrecher, UP; Wagner, P | 1 |
Heinecke, JW; Hsu, FF; Leeuwenburgh, C; Mueller, DM; Pennathur, S; Rasmussen, JE | 1 |
Abdalla, DS; Moriel, P | 1 |
Hazen, SL; Heinecke, JW | 1 |
Crowley, JR; Hazen, SL; Heinecke, JW; Mueller, DM | 1 |
Gon, Y; Hashimoto, N; Kikuchi, H; Nishiyama, A; Nozaki, K; Sono, H; Takagi, Y; Todaka, T; Yodoi, J | 1 |
Bian, H; Harris, PE; Reed, EF | 1 |
Britigan, BE; Buettner, GR; Gaut, JP; Heinecke, JW; Lin, TS; McCormick, ML | 1 |
Crowley, JR; Hazen, SL; Heinecke, JW; Hsu, FF; Leeuwenburgh, C; Mueller, DM; Rasmussen, JE; Turk, J | 1 |
Baker, CS; Creminon, C; Evans, TJ; Hall, RJ; Maclouf, J; Polak, JM; Pomerance, A; Yacoub, MH | 1 |
Stanbro, WD | 1 |
Hazen, SL; Hegele, RA; Heinecke, JW; Huff, MW; Miller, DB; Whitman, SC | 1 |
Leist, M; Ullrich, V; Zou, MH | 1 |
Gmeiner, B; Held, I; Hermann, M; Hofbauer, R; Kapiotis, S; Seelos, C | 1 |
Huang, Y; Jaffa, A; Koskinen, S; Lopes-Virella, MF; Takei, A | 1 |
Cummings, RD | 1 |
Francis, GA; Perry, RJ | 1 |
Sax, FL; Snapinn, SM; Théroux, P; Zhao, XQ | 1 |
Sutherland, WH; Upritchard, JE | 1 |
Gómez-Muñoz, A; Martens, JS; Steinbrecher, UP | 1 |
Beelaerts, WJ; Bosmans, JM; Bult, H; Cromheeke, KM; De Meyer, GR; Herman, AG; Kockx, MM; Vrints, CJ | 1 |
Crowley, JR; Hazen, SL; Heinecke, JW; Heller, JI; Pennathur, S; Salvay, DM; Wagner, P | 1 |
Haginaka, J; Kagota, S; Kunitomo, M; Yamaguchi, Y | 1 |
Kato, Y; Kitamoto, N; Naito, M; Nomura, H; Osawa, T; Wu, X | 1 |
Abu-Soud, HM; Hazen, SL; Podrez, EA | 1 |
Cap, A; Cohen, R; Eberhardt, RT; Farber, HW; Forgione, MA; Goldschmidt-Clermont, PJ; Heydrick, S; Klings, ES; Leopold, JA; Loscalzo, J; Moldovan, NI; Rudd, MA; Stark, R; Trolliet, M; Yaghoubi, M | 1 |
Brown, KK; Glass, CK; Li, AC; Palinski, W; Silvestre, MJ; Willson, TM | 1 |
Crowley, JR; Gaut, JP; Hazen, SL; Heinecke, JW; Hsu, FF | 1 |
Montalescot, G | 1 |
Averbook, A; Busuttil, SJ; Graham, DJ; Snajdar, RM | 1 |
Anderson, MM; Brennan, ML; Crowley, JR; Hazen, SL; Heinecke, JW; Jacob, JS; Lim, LL; Lusis, AJ; Mehta, AC; Qu, XD; Shi, W; Shih, DM; Wang, X | 1 |
Heinecke, JW; Leeuwenburgh, C; Litwak, KN; Pennathur, S; Wagner, JD | 1 |
Amarenco, P; Arveiler, D; Cambien, F; Elbaz, A; Evans, A; Gariepy, J; Grandchamp, B; Hetet, G; Kee, F; Morrison, C; Nicaud, V; Simon, A | 1 |
Heinecke, JW; Kirk, EA; LeBoeuf, RC | 1 |
Hirano, K; Hokari, S; Inoue, I; Katayama, S; Kawai, S; Komoda, T; Koyama, I; Matsunaga, T; Nakajima, T; Sonoda, M | 1 |
Arnal, JF; Darblade, B; Escargueil-Blanc, I; Jürgens, G; Nègre-Salvayre, A; Parthasarathy, S; Salvayre, R; Vacaresse, N | 1 |
Brown, AJ; Dean, RT; Kettle, AJ; Mashima, R; Niu, X; Senthilmohan, R; Stocker, R; Upston, JM; Wang, H | 1 |
Ballinger, SW; Burow, DL; Hu, ZY; Ischiropoulos, H; Knight-Lozano, CA; Pinkerton, KE; Uyeminami, D; Young, CG | 1 |
Chikara, S; Fukuda, N; Hu, WY; Kanmatsuse, K; Kishioka, H; Nakayama, M; Teng, J | 1 |
Sandberg, LB | 1 |
Franklin, EC; Rosenthal, CJ | 1 |
LaBella, FS | 1 |
Korotkina, RN; Perova, NV; Zhadanov, VS | 1 |
Loeper, J; Mouret, A | 1 |
Beneke, G; Buddecke, E; Platt, D | 1 |
Perova, NV | 1 |
11 review(s) available for tyrosine and Arteriosclerosis
Article | Year |
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Tyrosyl radical production by myeloperoxidase: a phagocyte pathway for lipid peroxidation and dityrosine cross-linking of proteins.
Topics: Arteriosclerosis; Cross-Linking Reagents; Free Radicals; Humans; Lipid Peroxidation; Oxidation-Reduction; Peroxidase; Phagocytes; Proteins; Tyrosine | 2002 |
Platelets: is aspirin sufficient or must we know how to pronounce abciximab?
Topics: Abciximab; Antibodies, Monoclonal; Arteriosclerosis; Aspirin; Blood Platelets; Clopidogrel; Endarterectomy, Carotid; Humans; Immunoglobulin Fab Fragments; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Pyridines; Ticlopidine; Tirofiban; Tyrosine | 2002 |
Amino acid and protein oxidation in cardiovascular disease.
Topics: Amino Acids; Animals; Arteriosclerosis; Cardiovascular Diseases; Free Radicals; Humans; Oxidation-Reduction; Phagocytes; Proteins; Reactive Nitrogen Species; Tyrosine | 2003 |
[Update on antithrombotic treatments in arterial diseases].
Topics: Abciximab; Antibodies, Monoclonal; Anticoagulants; Arteriosclerosis; Aspirin; Dipyridamole; Eptifibatide; Humans; Immunoglobulin Fab Fragments; Peptides; Platelet Aggregation Inhibitors; Pyridines; Thrombosis; Tirofiban; Treatment Outcome; Tyrosine | 2007 |
Pathways for oxidation of low density lipoprotein by myeloperoxidase: tyrosyl radical, reactive aldehydes, hypochlorous acid and molecular chlorine.
Topics: Aldehydes; Animals; Arteriosclerosis; Chlorine; Cholesterol, LDL; Free Radicals; Humans; Hypochlorous Acid; Lipoproteins, LDL; Macrophages; Oxidants; Oxidation-Reduction; Peroxidase; Tyrosine | 1997 |
Mechanisms of oxidative damage by myeloperoxidase in atherosclerosis and other inflammatory disorders.
Topics: Aldehydes; Arteriosclerosis; Chlorine; Humans; Inflammation; Oxidative Stress; Peroxidase; Phagocytes; Tyrosine | 1999 |
Structure and function of the selectin ligand PSGL-1.
Topics: Arteriosclerosis; Cell Adhesion; E-Selectin; Humans; Lectins; Ligands; Membrane Glycoproteins; Neutrophils; Structure-Activity Relationship; Tyrosine | 1999 |
Targeting HDL-mediated cellular cholesterol efflux for the treatment and prevention of atherosclerosis.
Topics: Arteriosclerosis; Biological Transport; Cholesterol; Free Radicals; Humans; Lipoproteins, HDL; Oxidation-Reduction; Tyrosine | 1999 |
Myeloperoxidase-generated oxidants and atherosclerosis.
Topics: Aldehydes; Amino Acids; Animals; Arteriosclerosis; Catalysis; Free Radicals; Humans; Lipoproteins, LDL; Nitro Compounds; Oxidants; Oxidation-Reduction; Peroxidase; Tyrosine | 2000 |
Value of antiplatelet therapy in preventing thrombotic events in generalized vascular disease.
Topics: Arteriosclerosis; Clopidogrel; Eptifibatide; Humans; Myocardial Infarction; Peptides; Platelet Aggregation Inhibitors; Stroke; Ticlopidine; Tirofiban; Tyrosine | 2000 |
Elastin structure in health and disease.
Topics: Aging; Amino Acid Sequence; Amino Acids; Animals; Arteriosclerosis; Calcium; Cholesterol; Copper; Cyanogen Bromide; Desmosine; Diet; Elastin; Microbial Collagenase; Models, Chemical; Molecular Weight; Protein Conformation; Swine; Tyrosine | 1976 |
2 trial(s) available for tyrosine and Arteriosclerosis
Article | Year |
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Statins promote potent systemic antioxidant effects through specific inflammatory pathways.
Topics: Antioxidants; Arteriosclerosis; Atorvastatin; Biomarkers; C-Reactive Protein; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Inflammation; Lipoproteins; Male; Middle Aged; Oxidation-Reduction; Prospective Studies; Pyrroles; Reactive Oxygen Species; Signal Transduction; Statistics, Nonparametric; Tyrosine | 2003 |
Intracoronary thrombus and platelet glycoprotein IIb/IIIa receptor blockade with tirofiban in unstable angina or non-Q-wave myocardial infarction. Angiographic results from the PRISM-PLUS trial (Platelet receptor inhibition for ischemic syndrome managemen
Topics: Aged; Angina, Unstable; Anticoagulants; Arteriosclerosis; Coronary Angiography; Coronary Artery Disease; Coronary Circulation; Coronary Thrombosis; Double-Blind Method; Drug Therapy, Combination; Electrocardiography; Female; Fibrinolytic Agents; Heparin; Humans; Male; Middle Aged; Myocardial Infarction; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Tirofiban; Treatment Outcome; Tyrosine | 1999 |
65 other study(ies) available for tyrosine and Arteriosclerosis
Article | Year |
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Mitochondrial integrity and function in atherogenesis.
Topics: Animals; Aorta; Apolipoproteins E; Arteriosclerosis; Disease Models, Animal; Disease Progression; DNA Damage; DNA, Mitochondrial; Heterozygote; Homozygote; Humans; Immunohistochemistry; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitochondria; Phenotype; Reactive Oxygen Species; Superoxide Dismutase; Tyrosine | 2002 |
Distinct renal injury in early atherosclerosis and renovascular disease.
Topics: Animals; Antioxidants; Arteriosclerosis; Cholesterol, Dietary; Disease Models, Animal; Disease Progression; Glomerular Filtration Rate; Hemodynamics; Hypercholesterolemia; Hypertension; Immunohistochemistry; Kidney; Kidney Function Tests; Kidney Tubules; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxidation-Reduction; Regional Blood Flow; Renal Artery Obstruction; Swine; Tomography, X-Ray Computed; Tyrosine; Vasodilator Agents | 2002 |
Long-term vitamin C treatment increases vascular tetrahydrobiopterin levels and nitric oxide synthase activity.
Topics: Animals; Aorta; Apolipoproteins E; Arteriosclerosis; Ascorbic Acid; Biopterins; Cyclic AMP; Cyclic GMP; Dietary Supplements; Disease Models, Animal; Endothelium, Vascular; Enzyme Activation; In Vitro Techniques; Lipids; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Superoxides; Time; Tyrosine; Vasomotor System; Vitamin E | 2003 |
Effects of chronic treatment with L-arginine on atherosclerosis in apoE knockout and apoE/inducible NO synthase double-knockout mice.
Topics: Animals; Aorta; Apolipoproteins E; Arginine; Arteriosclerosis; Biopterins; Blotting, Western; Cholesterol; Disease Models, Animal; Immunohistochemistry; Isoenzymes; Malondialdehyde; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Staining and Labeling; Thiobarbituric Acid Reactive Substances; Tyrosine | 2003 |
3-Nitrotyrosine in atherosclerotic blood vessels.
Topics: Arteriosclerosis; Blood Vessels; Case-Control Studies; Humans; Molecular Diagnostic Techniques; Nitrates; Nitrites; Spectrophotometry; Thoracic Arteries; Tyrosine; Up-Regulation | 2003 |
Lipid peroxidation and nitric oxide inactivation in postmenopausal women.
Topics: Adult; Aged; Arteriosclerosis; Cholesterol; Estradiol; Estrogens; Female; Humans; Lipid Peroxidation; Middle Aged; Nitric Oxide; Postmenopause; Premenopause; S-Nitrosothiols; Tyrosine; Vasodilation | 2003 |
Administration of tyrosyl radical-oxidized HDL inhibits the development of atherosclerosis in apolipoprotein E-deficient mice.
Topics: Animals; Aorta; Apolipoproteins E; Arteriosclerosis; Cells, Cultured; Cholesterol; Cholesterol, HDL; Female; Fibroblasts; Free Radicals; Humans; Lipoproteins, HDL; Male; Mice; Mice, Inbred C57BL; Oxidation-Reduction; Skin; Sterol O-Acyltransferase; Tyrosine | 2003 |
The effect of tumor necrosis factor-alpha on tissue specificity and selectivity to insulin signaling.
Topics: Animals; Antimetabolites; Antineoplastic Agents; Arteriosclerosis; Cells, Cultured; Deoxyglucose; Insulin; Insulin Receptor Substrate Proteins; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Muscle, Skeletal; Phosphoproteins; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Rats; Receptor, Insulin; Sensitivity and Specificity; Tumor Necrosis Factor-alpha; Tyrosine | 2003 |
Mechanisms involved in the stimulatory effect of advanced glycation end products on growth of rat aortic smooth muscle cells.
Topics: Animals; Aorta, Thoracic; Arteriosclerosis; Blood Glucose; Blotting, Western; Cell Count; Cell Division; CHO Cells; Cricetinae; Electrophoretic Mobility Shift Assay; Galectin 3; Glycation End Products, Advanced; Muscle, Smooth, Vascular; NF-kappa B; Phosphorylation; Rats; Rats, Inbred WKY; Receptor, Platelet-Derived Growth Factor beta; Reverse Transcriptase Polymerase Chain Reaction; Serum Albumin, Bovine; Stimulation, Chemical; Thymidine; Tyrosine | 2003 |
Fibrillar amyloid protein present in atheroma activates CD36 signal transduction.
Topics: Amyloid; Animals; Arteriosclerosis; Blotting, Western; CD36 Antigens; Cell Line, Tumor; Cells, Cultured; Foam Cells; Humans; Immunohistochemistry; Macrophages; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Protein Binding; Protein Conformation; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; src-Family Kinases; Time Factors; Transfection; Tumor Necrosis Factor-alpha; Tyrosine | 2004 |
Potential role of methionine sulfoxide in the inactivation of the chaperone GroEL by hypochlorous acid (HOCl) and peroxynitrite (ONOO-).
Topics: Amino Acid Sequence; Arteriosclerosis; Chaperonin 60; Chromatography; Chromatography, High Pressure Liquid; Electrophoresis, Polyacrylamide Gel; Humans; Hydrolysis; Hypochlorous Acid; Mass Spectrometry; Methionine; Methionine Sulfoxide Reductases; Molecular Chaperones; Molecular Sequence Data; Oxidants; Oxidoreductases; Oxygen; Peptides; Peroxynitrous Acid; Phagocytes; Protein Binding; Time Factors; Trypsin; Tyrosine | 2004 |
Fluvastatin inhibits raft dependent Fcgamma receptor signalling in human monocytes.
Topics: Antigen-Antibody Complex; Arteriosclerosis; Blotting, Western; Cells, Cultured; Fatty Acids, Monounsaturated; Flow Cytometry; Fluvastatin; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Interleukin-6; Matrix Metalloproteinase 1; Membrane Microdomains; Monocytes; Phosphorylation; Receptors, IgG; Signal Transduction; Tyrosine | 2004 |
Antioxidant intervention attenuates myocardial neovascularization in hypercholesterolemia.
Topics: Animals; Antioxidants; Arteriosclerosis; Ascorbic Acid; Cardiotonic Agents; Coronary Circulation; Diet, Atherogenic; Dinoprost; Enzyme Induction; Female; Gene Expression Profiling; Gene Expression Regulation; Heart; Hypercholesterolemia; Hypoxia-Inducible Factor 1, alpha Subunit; Imaging, Three-Dimensional; Myocardial Ischemia; Neovascularization, Pathologic; Oxidative Stress; Superoxide Dismutase; Swine; Tomography, X-Ray Computed; Transcription Factors; Tyrosine; Vascular Endothelial Growth Factor A; Vitamin E | 2004 |
Mild hyperhomocysteinemia induced by feeding rats diets rich in methionine or deficient in folate promotes early atherosclerotic inflammatory processes.
Topics: Animals; Aorta; Arteriosclerosis; Chemokine CCL2; Diet; Endothelium, Vascular; Folic Acid; Folic Acid Deficiency; Hyperhomocysteinemia; Inflammation; Intercellular Adhesion Molecule-1; Male; Malondialdehyde; Methionine; NF-kappa B; Nitric Oxide Synthase; Nitrites; Oxidative Stress; Rats; Rats, Sprague-Dawley; Tyrosine | 2004 |
Human atherosclerotic intima and blood of patients with established coronary artery disease contain high density lipoprotein damaged by reactive nitrogen species.
Topics: Arteries; Arteriosclerosis; Coronary Artery Disease; Coronary Vessels; Dose-Response Relationship, Drug; Epitopes; Gas Chromatography-Mass Spectrometry; Humans; Immunohistochemistry; Inflammation; Lipid Peroxides; Lipoproteins, HDL; Mass Spectrometry; Nitric Oxide; Nitrogen; Oxygen; Peroxidase; Peroxynitrous Acid; Reactive Nitrogen Species; Taurine; Time Factors; Tunica Intima; Tyrosine | 2004 |
Apolipoprotein A-I is a selective target for myeloperoxidase-catalyzed oxidation and functional impairment in subjects with cardiovascular disease.
Topics: Aged; Animals; Aorta; Apolipoprotein A-I; Arteriosclerosis; ATP Binding Cassette Transporter 1; ATP-Binding Cassette Transporters; Blotting, Western; Cardiovascular Diseases; Catalysis; Cell Line; Cholesterol; Cohort Studies; Female; Femoral Artery; Humans; Lipoproteins, HDL; Macrophages; Male; Mice; Middle Aged; Nitro Compounds; Oxidation-Reduction; Peroxidase; Tyrosine | 2004 |
The myeloperoxidase product hypochlorous acid oxidizes HDL in the human artery wall and impairs ABCA1-dependent cholesterol transport.
Topics: Amino Acid Sequence; Apolipoprotein A-I; Arteries; Arteriosclerosis; ATP Binding Cassette Transporter 1; ATP-Binding Cassette Transporters; Cholesterol, HDL; Chromatography, Liquid; Humans; Hypochlorous Acid; Mass Spectrometry; Molecular Sequence Data; Peroxidase; Tyrosine | 2004 |
Arsenic exposure exacerbates atherosclerotic plaque formation and increases nitrotyrosine and leukotriene biosynthesis.
Topics: Animals; Arachidonate 5-Lipoxygenase; Arsenites; Arteriosclerosis; Enzyme Inhibitors; Female; Leukotriene E4; Male; Mice; Muscle, Smooth, Vascular; Sodium Compounds; Tyrosine | 2004 |
Differential effects of exercise on aortic mitochondria.
Topics: Animals; Aorta; Apolipoproteins E; Arteriosclerosis; Cholesterol; Disease Models, Animal; Hypercholesterolemia; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Mitochondria; Mitochondrial ADP, ATP Translocases; Oxidative Stress; Physical Exertion; Risk Factors; Tyrosine | 2005 |
The antioxidant N-acetylcysteine prevents accelerated atherosclerosis in uremic apolipoprotein E knockout mice.
Topics: Acetylcysteine; Animals; Antioxidants; Aorta; Apolipoproteins E; Arteriosclerosis; Body Weight; Collagen; Female; Mice; Mice, Knockout; Tyrosine; Uremia | 2005 |
Dietary copper supplements modulate aortic superoxide dismutase, nitric oxide and atherosclerosis.
Topics: Animals; Aorta, Thoracic; Arteriosclerosis; Calcimycin; Carotid Arteries; Cholesterol; Copper; Dietary Supplements; Ionophores; Muscle, Smooth; Nitric Oxide; Oxidative Stress; Rabbits; Superoxide Dismutase; Tyrosine | 2005 |
[Histochemical characteristics of tyrosine in arteries of elastic and muscular types under normal conditions and in atherosclerosis].
Topics: Adolescent; Adult; Aged; Arteries; Arteriosclerosis; Female; Fetus; Histocytochemistry; Humans; Lipidoses; Middle Aged; Pregnancy; Tyrosine | 1966 |
Oxidative crosslinking of LDL protein induced by hemin: involvement of tyrosines.
Topics: Apolipoproteins B; Arteriosclerosis; Copper; Cross-Linking Reagents; Hemin; Humans; Lipoproteins, LDL; Oxidation-Reduction; Peroxides; Spectrometry, Fluorescence; Tyrosine | 1994 |
Inducible nitric oxide synthase is present within human atherosclerotic lesions and promotes the formation and activity of peroxynitrite.
Topics: Adult; Aged; Aged, 80 and over; Arteriosclerosis; Biomarkers; Blotting, Western; Female; Foam Cells; Humans; In Situ Hybridization; Macrophages; Male; Middle Aged; Muscle, Smooth, Vascular; Nitrates; Nitric Oxide Synthase; RNA, Messenger; Tyrosine | 1996 |
Do human atherosclerotic lesions contain nitrotyrosine?
Topics: Antibody Specificity; Arteriosclerosis; Blotting, Western; Chromatography, High Pressure Liquid; Humans; Immune Sera; Tyrosine | 1996 |
Reactive nitrogen intermediates promote low density lipoprotein oxidation in human atherosclerotic intima.
Topics: Arteries; Arteriosclerosis; Free Radicals; Humans; In Vitro Techniques; Lipoproteins, LDL; Nitrogen; Oxidation-Reduction; Serum Albumin, Bovine; Tyrosine | 1997 |
Mass spectrometric quantification of markers for protein oxidation by tyrosyl radical, copper, and hydroxyl radical in low density lipoprotein isolated from human atherosclerotic plaques.
Topics: Animals; Aorta; Arteriosclerosis; Cattle; Copper; Endothelium, Vascular; Gas Chromatography-Mass Spectrometry; Humans; Hydroxyl Radical; Lipoproteins, LDL; Mass Spectrometry; Oxidation-Reduction; Peroxidase; Phenylalanine; Tyrosine | 1997 |
Nitrotyrosine bound to beta-VLDL-apoproteins: a biomarker of peroxynitrite formation in experimental atherosclerosis.
Topics: Animals; Arteriosclerosis; Biomarkers; Blood Proteins; Cholesterol; Hypercholesterolemia; Lipoproteins, VLDL; Male; Nitrates; Rabbits; Triglycerides; Tyrosine | 1997 |
3-Chlorotyrosine, a specific marker of myeloperoxidase-catalyzed oxidation, is markedly elevated in low density lipoprotein isolated from human atherosclerotic intima.
Topics: Aorta; Apolipoproteins B; Arteriosclerosis; Biomarkers; Chlorine; Humans; Hypochlorous Acid; Lipoproteins; Lipoproteins, LDL; Oxidation-Reduction; Peroxidase; Phagocytes; Tyrosine | 1997 |
Mass spectrometric quantification of 3-chlorotyrosine in human tissues with attomole sensitivity: a sensitive and specific marker for myeloperoxidase-catalyzed chlorination at sites of inflammation.
Topics: Analysis of Variance; Aorta; Arteriosclerosis; Biomarkers; Calibration; Carbon; Carbon Isotopes; Catalysis; Chlorine; Female; Gas Chromatography-Mass Spectrometry; Humans; Hypochlorous Acid; Inflammation; Lipoproteins, LDL; Male; Peroxidase; Sensitivity and Specificity; Tyrosine | 1997 |
Expression of thioredoxin is enhanced in atherosclerotic plaques and during neointima formation in rat arteries.
Topics: Animals; Arteriosclerosis; Carotid Arteries; Catheterization; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Nude; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxidants; Rats; Rats, Wistar; RNA, Messenger; Thioredoxins; Tumor Cells, Cultured; Tunica Intima; Tyrosine | 1998 |
Ligation of HLA class I molecules on smooth muscle cells with anti-HLA antibodies induces tyrosine phosphorylation, fibroblast growth factor receptor expression and cell proliferation.
Topics: Antibodies; Arteriosclerosis; Cell Division; Cells, Cultured; Histocompatibility Antigens Class I; Humans; Muscle Proteins; Muscle, Smooth; Phosphorylation; Receptors, Fibroblast Growth Factor; Transplantation; Tyrosine | 1998 |
Electron paramagnetic resonance detection of free tyrosyl radical generated by myeloperoxidase, lactoperoxidase, and horseradish peroxidase.
Topics: Animals; Arteriosclerosis; Cattle; Electron Spin Resonance Spectroscopy; Free Radicals; Horseradish Peroxidase; Humans; Hydrogen Peroxide; Inflammation; Kinetics; Lactoperoxidase; Lipid Peroxidation; Oxidation-Reduction; Peroxidase; Pronase; Tyrosine | 1998 |
Detecting oxidative modification of biomolecules with isotope dilution mass spectrometry: sensitive and quantitative assays for oxidized amino acids in proteins and tissues.
Topics: Amino Acids; Arteriosclerosis; Gas Chromatography-Mass Spectrometry; Humans; Indicator Dilution Techniques; Isotopes; Lipoproteins, LDL; Oxidation-Reduction; Peroxidase; Phagocytes; Phenylalanine; Proteins; Reference Standards; Tyrosine | 1999 |
Cyclooxygenase-2 is widely expressed in atherosclerotic lesions affecting native and transplanted human coronary arteries and colocalizes with inducible nitric oxide synthase and nitrotyrosine particularly in macrophages.
Topics: Animals; Arteriosclerosis; Coronary Artery Bypass; Coronary Vessels; Cyclooxygenase 2; Graft Survival; Humans; Isoenzymes; Macrophages; Membrane Proteins; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitrogen Compounds; Prostaglandin-Endoperoxide Synthases; Rabbits; Tyrosine | 1999 |
A kinetic model of the system: tyrosyl radical-nitrogen oxide-superoxide ion.
Topics: Arteriosclerosis; Free Radicals; Humans; Ions; Lipid Peroxidation; Lipoproteins, LDL; Models, Chemical; Nitrates; Nitrogen Oxides; Superoxides; Tyrosine | 1999 |
Modification of type III VLDL, their remnants, and VLDL from ApoE-knockout mice by p-hydroxyphenylacetaldehyde, a product of myeloperoxidase activity, causes marked cholesteryl ester accumulation in macrophages.
Topics: Acetaldehyde; Animals; Apolipoproteins E; Arteriosclerosis; Cell Line; Cholesterol Esters; Esterification; Humans; Hyperlipoproteinemia Type III; Hypochlorous Acid; Interferon-gamma; Lipoprotein Lipase; Lipoproteins, VLDL; Macrophages; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Oxidation-Reduction; Peroxidase; Phenol; Poly I; Receptors, Immunologic; Receptors, Lipoprotein; Receptors, Scavenger; Scavenger Receptors, Class A; Scavenger Receptors, Class B; Sterol O-Acyltransferase; Triglycerides; Tyrosine | 1999 |
Selective nitration of prostacyclin synthase and defective vasorelaxation in atherosclerotic bovine coronary arteries.
Topics: Animals; Arteriosclerosis; Cattle; Coronary Vessels; Cytochrome P-450 Enzyme System; Immunohistochemistry; Intramolecular Oxidoreductases; Nitrates; Prostaglandins; Tyrosine; Vasodilation | 1999 |
Salicylate promotes myeloperoxidase-initiated LDL oxidation: antagonization by its metabolite gentisic acid.
Topics: Arteriosclerosis; Aspirin; Free Radical Scavengers; Free Radicals; Gentisates; Humans; Hydroxybenzoates; In Vitro Techniques; Lipid Peroxidation; Lipoproteins, LDL; Neutrophils; Oxidants; Oxidation-Reduction; Peroxidase; Phenols; Salicylic Acid; Tyrosine | 1999 |
Oxidized LDL-containing immune complexes induce Fc gamma receptor I-mediated mitogen-activated protein kinase activation in THP-1 macrophages.
Topics: Animals; Antigen-Antibody Complex; Arteriosclerosis; Autoantibodies; Calcium-Calmodulin-Dependent Protein Kinases; Cell Line; Enzyme Activation; Humans; Lipoproteins, LDL; Macrophages; Phosphorylation; Rabbits; Receptors, IgG; Tetradecanoylphorbol Acetate; Time Factors; Tyrosine | 1999 |
Oxidation of heparin-treated low density lipoprotein by peroxidases.
Topics: Antioxidants; Arteries; Arteriosclerosis; Binding Sites; Butylated Hydroxytoluene; Heparin; Horseradish Peroxidase; Humans; Hydrogen Peroxide; Lipoproteins, LDL; Oxidation-Reduction; Peroxidase; Peroxidases; Proteoglycans; Thiobarbituric Acid Reactive Substances; Tunica Intima; Tyrosine | 1999 |
Stimulation of phospholipase D activity by oxidized LDL in mouse peritoneal macrophages.
Topics: Animals; Arteriosclerosis; Calcium; Cells, Cultured; Ceramides; GTP-Binding Proteins; Lipoproteins, LDL; Lysophosphatidylcholines; Macrophages, Peritoneal; Mice; Mice, Knockout; Phospholipase D; Phosphorylation; Platelet Membrane Glycoproteins; Protein Kinase C; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Tyrosine | 2000 |
Inducible nitric oxide synthase colocalizes with signs of lipid oxidation/peroxidation in human atherosclerotic plaques.
Topics: Aged; Analysis of Variance; Arteriosclerosis; Biomarkers; Blotting, Western; Carotid Arteries; Ceroid; Endarterectomy, Carotid; Female; Humans; Immunohistochemistry; Lipid Peroxidation; Macrophages; Male; Microscopy, Electron; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tyrosine | 1999 |
p-hydroxyphenylacetaldehyde, an aldehyde generated by myeloperoxidase, modifies phospholipid amino groups of low density lipoprotein in human atherosclerotic intima.
Topics: Acetaldehyde; Arteriosclerosis; Humans; Hydrogen Peroxide; Kinetics; Lipoproteins, LDL; Neutrophils; Peroxidase; Phenol; Phosphatidylethanolamines; Phospholipids; Tunica Intima; Tyrosine | 2000 |
Peroxynitrite-generating species: good candidate oxidants in aqueous extracts of cigarette smoke.
Topics: Arteriosclerosis; Humans; Nicotiana; Nitrates; Oxidants; Plants, Toxic; Smoke; Smoking; Tyrosine | 2000 |
Immunochemical detection of protein dityrosine in atherosclerotic lesion of apo-E-deficient mice using a novel monoclonal antibody.
Topics: Animals; Antibodies, Monoclonal; Antibody Specificity; Antigens; Aorta, Thoracic; Apolipoproteins E; Arteriosclerosis; Binding, Competitive; Biomarkers; Crystallins; Enzyme-Linked Immunosorbent Assay; Haptens; Hydrogen Peroxide; Immune Sera; Immunohistochemistry; Male; Mice; Mice, Inbred BALB C; Molecular Weight; Oxidants; Phenylpropionates; Tyrosine | 2000 |
Endothelial dysfunction in a murine model of mild hyperhomocyst(e)inemia.
Topics: Acetylcholine; Animals; Aorta; Arteriosclerosis; Cystathionine beta-Synthase; Dinoprost; Disease Models, Animal; Endothelium, Vascular; F2-Isoprostanes; Heterozygote; Humans; Hyperhomocysteinemia; In Vitro Techniques; Lipid Peroxides; Mice; Mice, Mutant Strains; Nitroprusside; Reactive Oxygen Species; Risk Factors; Thrombosis; Tyrosine; Vasodilation | 2000 |
Peroxisome proliferator-activated receptor gamma ligands inhibit development of atherosclerosis in LDL receptor-deficient mice.
Topics: Animals; Arteriosclerosis; Base Sequence; CD36 Antigens; DNA Primers; Female; Gene Expression; Humans; Insulin Resistance; Ligands; Male; Matrix Metalloproteinase 9; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Oxazoles; Receptors, Cytoplasmic and Nuclear; Receptors, Immunologic; Receptors, LDL; Receptors, Lipoprotein; Receptors, Scavenger; RNA, Messenger; Rosiglitazone; Scavenger Receptors, Class B; Thiazoles; Thiazolidinediones; Transcription Factors; Tumor Necrosis Factor-alpha; Tyrosine | 2000 |
Elevated levels of protein-bound p-hydroxyphenylacetaldehyde, an amino-acid-derived aldehyde generated by myeloperoxidase, are present in human fatty streaks, intermediate lesions and advanced atherosclerotic lesions.
Topics: Acetaldehyde; Antioxidants; Aorta; Arteriosclerosis; Chlorides; Gas Chromatography-Mass Spectrometry; Humans; Lipid Metabolism; Lipoproteins, LDL; Lysine; Peroxidase; Phenol; Schiff Bases; Solubility; Tunica Intima; Tyrosine; Water | 2000 |
Inhibition of endothelial cell migration by cigarette smoke condensate.
Topics: Arteriosclerosis; Cell Movement; Cells, Cultured; Endothelium, Vascular; Humans; In Vitro Techniques; Phosphorylation; Signal Transduction; Smoking; Tyrosine; Umbilical Veins | 2001 |
Increased atherosclerosis in myeloperoxidase-deficient mice.
Topics: Animals; Arteriosclerosis; Candida albicans; Humans; Hypochlorous Acid; Mice; Mice, Inbred C57BL; Neutrophils; Oxidation-Reduction; Peroxidase; Phagocytes; Tyrosine | 2001 |
A hydroxyl radical-like species oxidizes cynomolgus monkey artery wall proteins in early diabetic vascular disease.
Topics: Animals; Aorta; Arteriosclerosis; Diabetes Mellitus, Experimental; Glucose; Glycated Hemoglobin; Hydroxyl Radical; Lipids; Macaca fascicularis; Male; Mass Spectrometry; Oxidation-Reduction; Time Factors; Tyrosine | 2001 |
Association studies between haemochromatosis gene mutations and the risk of cardiovascular diseases.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Arteriosclerosis; Aspartic Acid; Brain Infarction; Cardiovascular Diseases; Case-Control Studies; Cysteine; Female; France; Genetic Predisposition to Disease; Genotype; Hemochromatosis; Hemochromatosis Protein; Histidine; Histocompatibility Antigens Class I; HLA Antigens; Humans; Male; Membrane Proteins; Middle Aged; Mutation; Myocardial Infarction; Northern Ireland; Polymorphism, Genetic; Prevalence; Prospective Studies; Tyrosine; Ultrasonography; United Kingdom | 2001 |
Iron overload diminishes atherosclerosis in apoE-deficient mice.
Topics: Animals; Apolipoproteins E; Arteriosclerosis; Cholesterol; Female; Iron Carbonyl Compounds; Iron Overload; Liver; Mice; Mice, Knockout; Organometallic Compounds; Oxidation-Reduction; RNA, Messenger; Triglycerides; Tyrosine | 2001 |
Modulation of reactive oxygen species in endothelial cells by peroxynitrite-treated lipoproteins.
Topics: Arteriosclerosis; Catalase; Cell Survival; Cells, Cultured; Chromatography, High Pressure Liquid; Electron Spin Resonance Spectroscopy; Endothelium, Vascular; Free Radical Scavengers; Humans; Lipoproteins; Lipoproteins, HDL; NADPH Oxidases; Nitric Oxide; Nitric Oxide Synthase; Peroxynitrous Acid; Prostaglandin-Endoperoxide Synthases; Reactive Oxygen Species; Superoxide Dismutase; Tyrosine | 2001 |
Mildly oxidized LDL induces activation of platelet-derived growth factor beta-receptor pathway.
Topics: Aldehydes; Animals; Anti-Bacterial Agents; Antioxidants; Aorta; Arteriosclerosis; Autocrine Communication; Cells, Cultured; Ceramides; Chloroquine; Diet, Atherogenic; Enzyme Inhibitors; Humans; Hydrogen Peroxide; Lipoproteins, LDL; Macrolides; Male; Muscle, Smooth, Vascular; Oxidative Stress; Phosphorylation; Rabbits; Reactive Oxygen Species; Receptor, Platelet-Derived Growth Factor beta; Signal Transduction; Sphingomyelins; Tyrosine | 2001 |
Disease stage-dependent accumulation of lipid and protein oxidation products in human atherosclerosis.
Topics: Adult; Aged; Antioxidants; Aorta; Arteriosclerosis; Cholesterol; Cholesterol Esters; Disease Progression; Humans; Lipid Metabolism; Middle Aged; Oxidation-Reduction; Phenylalanine; Proteins; Tyrosine | 2002 |
Cigarette smoke exposure and hypercholesterolemia increase mitochondrial damage in cardiovascular tissues.
Topics: Animals; Aorta; Arteriosclerosis; Cardiovascular System; Disease Progression; DNA Damage; DNA, Mitochondrial; Hypercholesterolemia; Inhalation Exposure; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitochondria, Heart; Mitochondrial ADP, ATP Translocases; Myocardium; Oxidative Stress; Risk Factors; Superoxide Dismutase; Tobacco Smoke Pollution; Tyrosine | 2002 |
Troglitazone inhibits growth and improves insulin signaling by suppression of angiotensin II action in vascular smooth muscle cells from spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Arteriosclerosis; Cell Division; Cells, Cultured; Chromans; Depression, Chemical; DNA; Growth Substances; Insulin Receptor Substrate Proteins; Insulin Resistance; Male; Muscle, Smooth, Vascular; Phosphatidylinositol 3-Kinases; Phosphoproteins; Phosphorylation; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Signal Transduction; Thiazoles; Thiazolidinediones; Troglitazone; Tyrosine | 2002 |
Age-associated changes of an amyloid related serum component.
Topics: Acute Disease; Adolescent; Adult; Aged; Aging; Amyloid; Amyloidosis; Arteriosclerosis; Child; Child, Preschool; Chromatography, Gel; Chronic Disease; Diabetes Mellitus; Female; Follow-Up Studies; Humans; Infant; Infant, Newborn; Iodine Radioisotopes; Middle Aged; Osteoarthritis; Pregnancy; Radioimmunoassay; Tyrosine | 1974 |
Arterial mesenchyme and arteriosclerosis. Enzymic vs non-enzymic factors in the deterioration of connective tissue.
Topics: Adolescent; Adult; Age Factors; Aged; Aging; Animals; Aorta; Arteries; Arteriosclerosis; Blood Platelets; Cattle; Child; Collagen; Connective Tissue; Culture Techniques; Elastic Tissue; Elastin; Female; Fluorescence; Humans; Leukocytes; Male; Middle Aged; Pancreatic Elastase; Phenylalanine; Pregnancy; Proteins; Solubility; Tyrosine; Ultraviolet Rays; X-Ray Diffraction | 1974 |
[Distribution of parenterally administered C 14 -hyaluronidase in the organs and tissues in experimental arteriosclerosis].
Topics: Animals; Aorta; Arteriosclerosis; Blood Proteins; Brain; Carbon Isotopes; Diet, Atherogenic; Disease Models, Animal; Fibrin; Hyaluronoglucosaminidase; Kidney; Liver; Male; Methods; Muscles; Myocardium; Pancreas; Rats; Tendons; Time Factors; Tyrosine | 1971 |
[Contribution to the study of elastin in human and experimental atheroma].
Topics: Adult; Age Factors; Aged; Alanine; Amino Acids; Animals; Aorta; Arteries; Arteriosclerosis; Elastin; Humans; Infant; Infant, Newborn; Lysine; Methods; Middle Aged; Phenylalanine; Rabbits; Tyrosine | 1969 |
[Studies on the comparability of chemical and histochemical findings in human aortas changed by arteriosclerosis].
Topics: Adolescent; Adult; Age Factors; Aged; Aortic Diseases; Arteriosclerosis; Child; Child, Preschool; Cholesterol; Connective Tissue; Female; Hexosamines; Histocytochemistry; Humans; Hydroxyproline; Infant; Infant, Newborn; Male; Middle Aged; Tryptophan; Tyrosine | 1967 |
[A study of the biosynthesis of proteins of organs and tissue in experimental atherosclerosis].
Topics: Adrenal Glands; Animals; Aorta; Arteriosclerosis; Carbon Isotopes; Diet, Atherogenic; Glycine; Intestinal Mucosa; Kidney; Liver; Myocardium; Pancreas; Protein Biosynthesis; Rats; Spleen; Tyrosine | 1968 |