tyrosine has been researched along with Adenocarcinoma in 98 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (12.24) | 18.7374 |
| 1990's | 23 (23.47) | 18.2507 |
| 2000's | 45 (45.92) | 29.6817 |
| 2010's | 15 (15.31) | 24.3611 |
| 2020's | 3 (3.06) | 2.80 |
| Authors | Studies |
|---|---|
| Govindarajan, V; Kuracha, MR; Loggie, BW; McVicker, BL; Tobi, M | 1 |
| Anzai, N; Furihata, T; Higuchi, K; Kaneko, M; Morio, H; Muto, Y; Nakagawa, K; Ohno, Y; Okunushi, K; Otsuka, Y; Reien, Y; Sakamoto, S; Shimojo, N; Wakashin, H; Watanabe, Y | 1 |
| Alexeev, EE; Cartwright, IM; Colgan, SP; Dowdell, AS; Henen, MA; Lanis, JM; Lee, JS; Onyiah, JC; Ornelas, A; Schaefer, REM; Vögeli, B | 1 |
| Awasthi, S; Bansal, M; Belkina, N; Biswas, R; Califano, A; Chaerkady, R; Charles Jacob, HK; Cultraro, CM; Gao, S; Guha, U; Kashyap, MK; Kirkali, G; Maity, T; Marimuthu, A; Pandey, A; Pitts, S; Singh, S; Venugopalan, A; Zhang, X | 1 |
| Choi, S; Jang, B; Lee, ST; Lee, W; Oh, ES; Park, J; Shin, DH; Yun, JH | 1 |
| Ghishan, FK; Jagadish, B; Kiela, PR; Kojs, P; Martinez, JD; Mash, EA; Radhakrishnan, VM; Ramalingam, R; Young, G | 1 |
| Altiok, S; Doshi, P; Fulp, W; Haura, EB; Sasser, K; Smith, MA; Song, L | 1 |
| Hirano, H; Ito, H; Kimura, Y; Kurata, Y; Miyagi, Y; Nakayama, H; Nishi, M; Okayama, A; Oshita, F; Ryo, A | 1 |
| De Maria, R; Duranti, E; Eramo, A; Fecchi, K; Gallo, E; Milella, M; Mottolese, M; Pilozzi, E; Policicchio, E; Salvati, V; Sette, G; Tartaglia, M; Visca, P | 1 |
| Dai, Z; Diao, Y; Kang, H; Lin, S; Ma, X; Min, W; Wang, X; Zhao, Y | 1 |
| Hua, SF; Wang, YM; Xue, FX; Zhang, LZ; Zhao, J | 1 |
| Ahn, D; Ang, M; Bronte-Tinkew, DM; Franco, A; Jones, NL; Mimuro, H; Peek, RM; Ropeleski, MJ; Sasakawa, C; Terebiznik, M | 1 |
| Hao, X; Ju, J; Lambert, JD; Lee, MJ; Lu, G; Newmark, HL; Xiao, H; Yang, CS | 1 |
| Hikri, E; Nir, U; Shpungin, S | 1 |
| Allameh, A; Nasseri-Moghaddam, S; Rasmi, Y; Sadreddini, M; Sharifi, R; Tavangar, SM | 1 |
| Unger, EC | 1 |
| Becker, A; Chiappori, A; Haura, EB; Sommers, E; Song, L | 1 |
| Ren, YP; Tang, AG; Xiang, ZY; Zhou, QX | 1 |
| Endo, K; Hanaoka, H; Ishioka, NS; Ohshima, Y; Oriuchi, N; Sugo, Y; Tominaga, H; Watanabe, S | 1 |
| Carneiro, F; Ferreira, RM; Figueiredo, C; Leite, M; Machado, JC | 1 |
| Kita, K; Koizumi, H; Matsumoto, K; Mitsudomi, T; Nakagawa, T; Nakamura, T; Suda, K; Takeuchi, S; Yamada, T; Yano, S | 1 |
| Geng, SM; He, C; Kuang, YY; Lao, WF; Mo, LJ; Wang, D | 1 |
| Aghi, MK; Brumwell, AN; Chapman, HA; Jablons, DM; Kwan, I; McDonald, DM; Sennino, B; Tan, K; Ulsamer, A; Wei, Y; Xi, Y | 1 |
| Broussard, SR; Dantzer, R; Freund, GG; Kelley, KW; Shen, WH; Zhou, JH | 1 |
| Wei, L; Yang, Y; Yu, Q; Zhang, X | 1 |
| Benjannet, S; Chrétien, M; Khatib, AM; Seidah, NG; Siegfried, G | 1 |
| Baba, T; Koizumi, M; Kudo, R; Suzuki, T; Yamanaka, I; Yamashita, S | 1 |
| Lai, YP; Lin, JT; Lin, TZ; Wang, JT; Yang, JC | 1 |
| Cotarla, I; Furth, PA; Gehan, E; Ren, S; Singh, B; Zhang, Y | 1 |
| Ashley, SW; Duxbury, MS; Ito, H; Whang, EE; Zinner, MJ | 1 |
| Ahn, B; Hahm, KB; Jang, DD; Kim, DY; Kim, YB; Nam, KT; Oh, SY; Yang, KH | 1 |
| Kohno, H; Sugie, S; Suzuki, R; Tanaka, T | 1 |
| Koh, Y; Koizumi, F; Nishio, K; Saijo, N; Taguchi, F; Tamura, T | 1 |
| Arbeille, B; Fauvel-Lafeve, F; Gomes, N; Lebos, C; Legrand, C; Vassy, J | 1 |
| Choudary, A; Freeman, JW; Venkatasubbarao, K | 1 |
| Battistini, L; Borsellino, G; Bronte, V; Gallana, K; Gri, G; Iafrate, M; Kasic, T; Marigo, I; Pagano, F; Prayer-Galetti, T; Viola, A | 1 |
| Li, LG; Xu, HM | 1 |
| Kucerová, D; Sloncová, E; Tuhácková, Z; Turecková, J; Vojtechová, M | 1 |
| Cody, DD; Dackor, J; Fujimoto, N; Hanna, AE; Herbst, R; Iwanaga, K; Kalyankrishna, S; Kurie, JM; Massarelli, E; Minna, JD; Peyton, M; Price, RE; Sato, M; Shay, JW; Tang, X; Threadgill, DW; Wislez, M; Wistuba, II; Zhang, J | 1 |
| Bancel, B; Esteve, J; Ohshima, H; Pignatelli, B; Souquet, JC; Toyokuni, S | 1 |
| Samant, GV; Sylvester, PW | 1 |
| Aburatani, H; Akiyama, T; Azuma, T; Hatakeyama, M; Higashi, H; Kurashima, Y; Murata-Kamiya, N; Peek, RM; Saito, Y; Teishikata, Y; Yamahashi, Y | 1 |
| Aggarwal, BB; Ahn, KS; Chaturvedi, MM; Sethi, G | 1 |
| Cerny, RL; Gendler, SJ; Hollingsworth, MA; Kazlauskas, A; Shanmugam, K; Singh, PK; Swanson, BJ; Wen, Y | 1 |
| Bouancheau, D; Denis, MG; Jarry, A; Laboisse, CL; Masson, D; Mosnier, JF; Mottier, S; Toquet, C | 1 |
| Casson, AG; Geldenhuys, L; Guernsey, DL; Hainaut, P; Porter, GA; Risch, H; Vaninetti, NM | 1 |
| Aburatani, H; Fukayama, M; Goto, A; Ishikawa, S; Matsubara, D; Miyazawa, K; Nakamura, Y; Niki, T; Ota, S; Sachiko, O | 1 |
| Chen, Z; Ghafourifar, P; Parihar, A; Parihar, MS | 1 |
| Finegold, MJ; Weinberg, AG | 1 |
| Daya-Makin, M; Hogg, JC; Lipp, M; Mogentale, TL; Parchomchuk, J; Pelech, SL; Sanghera, JS | 1 |
| Homma, MK; Homma, Y; Namba, M; Yuasa, Y | 1 |
| Chess, PR; Finkelstein, JN; Ryan, RM | 1 |
| Jia, XS; Sun, AJ; Zhang, DR | 1 |
| Dizdaroglu, M; Hiai, H; Mori, T; Toyokuni, S | 1 |
| Iwase, T; Kino, I; Naito, Y; Sugimura, H; Suzuki, M; Tanaka, M | 1 |
| Fontecave, M; Henry, Y; Lepoivre, M; Roy, B | 1 |
| Capolongo, L; Ciomei, M; Geroni, C; Grandi, M; Melegaro, G; Pastori, W; Pennella, G | 1 |
| Falkow, S; Segal, ED; Tompkins, LS | 1 |
| Akedo, H; Imamura, F; Isoai, A; Kitagawa, I; Kobayashi, M; Mukai, M; Shinkai, K | 1 |
| Hosoe, S; Kijima, T; Kishimoto, T; Kumagai, T; Mori, M; Osaki, T; Sakuma, T; Tachibana, I; Tanio, Y; Ueno, K | 1 |
| Abe, H; Chihara, K; Kaji, H; Mizuno, I; Okimura, Y; Takahashi, T; Takahashi, Y; Uchiyama, T | 1 |
| Fujishima, H; Masumoto, N; Nakano, S; Niho, Y; Tatsumoto, T | 1 |
| Chen, X; Curtis, SK; Goldstein, SR; Yang, CS; Yang, GY | 1 |
| Birembault, P; Nawrocki, B; Polette, M; Tournier, JM; Van Hengel, J; Van Roy, F | 1 |
| Cai, J; Jiang, WG; Mansel, RE | 1 |
| Hioki, K; Kameshita, I; Mohri, T; Suzuki, S; Takatani, S; Tokunaga, R | 1 |
| Ellis, C; Green, M; MacMillan-Crow, LA; Thompson, JA; Vickers, SM | 1 |
| Kojima, M; Matsunari, Y; Mibu, R; Morisaki, T; Tanaka, M; Tsukahara, Y; Uchiyama, A | 1 |
| Horseman, ND; Lockefeer, JA; Pratt, SL; Vomachka, AJ | 1 |
| Greendorfer, JS; MacMillan-Crow, LA; Thompson, JA; Vickers, SM | 1 |
| Oberley, LW; Oberley, TD; Szweda, LI; Zhong, W | 1 |
| Cho, H; Dean, M; Gerrard, B; Han, SU; Jennings, B; Lee, JH; Schmidt, L; Vande Woude, GF; Zbar, B | 1 |
| Campbell, CL; Jiang, Z; Savarese, DM; Savarese, TM | 1 |
| Wei, L; Yang, Y; Yu, Q | 1 |
| Eguchi, K; Hirohashi, S; Iba, S; Imamura, H; Kondo, H; Matsuno, Y; Niki, T; Saitoh, Y; Tokunou, M; Tsuda, H; Yamada, T | 1 |
| Akaike, T; Hayashida, K; Maeda, H; Okamoto, T; Okuyama, A; Wu, J | 1 |
| Gabius, HJ; Lala, PK; Lan, Y; Timoshenko, AV | 1 |
| Backert, S; Brinkmann, V; Meyer, TF; Moese, S; Selbach, M | 1 |
| El-Hariry, I; Lemoine, NR; Pignatelli, M | 1 |
| Angelberger, P; Dudczak, R; Füger, B; Kletter, K; Kurtaran, A; Leimer, M; Li, SR; Novotny, C; Patri, P; Raderer, M; Traub, T; Virgolini, I; Wogritsch, S | 1 |
| Ahmed, F; Albanese, C; Bouzahzah, B; Chan, A; Condeelis, J; Der, CJ; Joyce, D; Lisanti, MP; Minden, A; Pestell, RG; Pixley, F; Segall, JD; Symons, M | 1 |
| Echizenya, M; Hiai, H; Imamura, M; Kondo, S; Onodera, H; Ozeki, M; Tachibana, T; Toyokuni, S; Tsuruyama, T | 1 |
| Adriance, MC; Gendler, SJ; McConnell, EJ; Pockaj, B; Schroeder, JA; Thompson, MC | 1 |
| Arvanitakis, C; Greenberger, NJ | 1 |
| Goldfeder, A; Mukerjee, H | 1 |
| Khazaie, K; Kittmann, A; Lichtner, RB; Schirrmacher, V; Ullrich, A; Wiedemuth, M | 1 |
| Flaman, JM; Henry, Y; Lepoivre, M | 1 |
| Baba, M; Iishi, H; Taniguchi, H; Tatsuta, M | 1 |
| Raubenheimer, EJ; Thein, T; van Heerden, WF | 1 |
| Bolen, JB; DeSeau, V; Rosen, N | 1 |
| Bistrian, BR; Blackburn, GL; Hunter, DC; Weintraub, M | 1 |
| Harris, BR; Shipkey, F | 1 |
| Brandt, MB; Kuttner, RE; Lorincz, AB | 1 |
| Korfsmeier, KH | 1 |
| Good, RA; Jose, DG | 1 |
| Barth, RF; Dunn, DR | 1 |
| Lindblad, B | 1 |
| Theuer, RC | 1 |
2 review(s) available for tyrosine and Adenocarcinoma
| Article | Year |
|---|---|
Primary hepatic tumors of childhood.
Topics: Adenocarcinoma; Adenoma; Adolescent; Adult; Bile Duct Neoplasms; Bile Ducts; Carcinoma, Hepatocellular; Child; Child, Preschool; Female; Hemangioma; Hemangiosarcoma; Hepatitis; Hepatitis B; Humans; Hyperplasia; Infant; Liver Cirrhosis, Biliary; Liver Neoplasms; Male; Metabolism, Inborn Errors; Neoplasms, Germ Cell and Embryonal; Prognosis; Sex Factors; Tyrosine | 1983 |
Tyrosine-rich crystalloids in a polymorphous low-grade adenocarcinoma.
Topics: Adenocarcinoma; Adult; Crystallization; Female; Humans; Salivary Gland Neoplasms; Salivary Glands, Minor; Tyrosine | 1990 |
1 trial(s) available for tyrosine and Adenocarcinoma
| Article | Year |
|---|---|
Branched chain amino acids as the protein component of parenteral nutrition in cancer cachexia.
Topics: Abdominal Neoplasms; Adenocarcinoma; Amino Acids; Amino Acids, Branched-Chain; Cachexia; Humans; Leucine; Parenteral Nutrition, Total; Prospective Studies; Proteins; Random Allocation; Tyrosine | 1989 |
95 other study(ies) available for tyrosine and Adenocarcinoma
| Article | Year |
|---|---|
Pictilisib-Induced Resistance Is Mediated through FOXO1-Dependent Activation of Receptor Tyrosine Kinases in Mucinous Colorectal Adenocarcinoma Cells.
Topics: Adenocarcinoma; Colorectal Neoplasms; Forkhead Box Protein O1; Forkhead Transcription Factors; Humans; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Receptor Protein-Tyrosine Kinases; Tyrosine | 2023 |
JPH203, a newly developed anti-cancer drug, shows a preincubation inhibitory effect on L-type amino acid transporter 1 function.
Topics: Adenocarcinoma; Antineoplastic Agents; Benzoxazoles; Colonic Neoplasms; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; HT29 Cells; Humans; Large Neutral Amino Acid-Transporter 1; Leucine; Time Factors; Tyrosine | 2020 |
Microbial-derived indoles inhibit neutrophil myeloperoxidase to diminish bystander tissue damage.
Topics: Adenocarcinoma; Animals; Bystander Effect; Colitis; Colorectal Neoplasms; Halogenation; Humans; Indoles; Mice; Mice, Inbred C57BL; Microbiota; Neutrophils; Peroxidase; Tumor Cells, Cultured; Tyrosine | 2021 |
Quantitative Tyrosine Phosphoproteomics of Epidermal Growth Factor Receptor (EGFR) Tyrosine Kinase Inhibitor-treated Lung Adenocarcinoma Cells Reveals Potential Novel Biomarkers of Therapeutic Response.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Afatinib; Biomarkers, Tumor; Cell Line, Tumor; Cluster Analysis; ErbB Receptors; Erlotinib Hydrochloride; Humans; Isotope Labeling; Lung Neoplasms; Mass Spectrometry; Mutation; Phosphorylation; Phosphotyrosine; Protein Kinase Inhibitors; Proteomics; Quinazolines; Reproducibility of Results; Signal Transduction; Tyrosine | 2017 |
Tyrosine 51 residue of the syndecan-2 extracellular domain is involved in the interaction with and activation of pro-matrix metalloproteinase-7.
Topics: Adenocarcinoma; Carcinogenesis; Cell Membrane; Colonic Neoplasms; Enzyme Activation; Extracellular Matrix; HT29 Cells; Humans; Magnetic Resonance Spectroscopy; Matrix Metalloproteinase 7; Molecular Docking Simulation; Mutagenesis; Protein Conformation, alpha-Helical; Protein Domains; Signal Transduction; Syndecan-2; Transfection; Tyrosine | 2019 |
pTyr421 cortactin is overexpressed in colon cancer and is dephosphorylated by curcumin: involvement of non-receptor type 1 protein tyrosine phosphatase (PTPN1).
Topics: Adenocarcinoma; Antineoplastic Agents; Blotting, Western; Catenins; Cell Line, Tumor; Cell Membrane; Cell Movement; Colorectal Neoplasms; Cortactin; Curcumin; Delta Catenin; Gene Expression Regulation, Neoplastic; HCT116 Cells; HT29 Cells; Humans; Immunohistochemistry; Microscopy, Confocal; Phosphorylation; Protein Binding; Protein Processing, Post-Translational; Protein Tyrosine Phosphatase, Non-Receptor Type 1; Reverse Transcriptase Polymerase Chain Reaction; Tyrosine | 2014 |
Antitumor efficacy of the anti-interleukin-6 (IL-6) antibody siltuximab in mouse xenograft models of lung cancer.
Topics: Adenocarcinoma; Animals; Antibodies, Monoclonal; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cell Line, Tumor; Disease Models, Animal; Erlotinib Hydrochloride; Female; Fibroblasts; Humans; Interleukin-6; Lung Neoplasms; Mice; Phosphorylation; Proto-Oncogene Proteins; Proto-Oncogene Proteins p21(ras); Quinazolines; ras Proteins; Serine; STAT3 Transcription Factor; Tyrosine | 2014 |
Identification of Tyrosine-Phosphorylated Proteins Upregulated during Epithelial-Mesenchymal Transition Induced with TGF-β.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Adult; Aged; Aged, 80 and over; Cell Line, Tumor; Early Diagnosis; Epithelial Cells; Epithelial-Mesenchymal Transition; Female; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Lymphotoxin-alpha; Male; Microfilament Proteins; Middle Aged; Neoplasm Staging; Peptides; Phosphorylation; Prognosis; Proto-Oncogene Proteins c-met; Receptor, trkC; Survival Analysis; Tensins; Tyrosine | 2015 |
Tyr1068-phosphorylated epidermal growth factor receptor (EGFR) predicts cancer stem cell targeting by erlotinib in preclinical models of wild-type EGFR lung cancer.
Topics: Adenocarcinoma; Aged; Animals; Antineoplastic Agents; Apoptosis; Biomarkers, Pharmacological; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cell Line, Tumor; Drug Evaluation, Preclinical; ErbB Receptors; Erlotinib Hydrochloride; Female; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Male; Mice; Mice, SCID; Middle Aged; Neoplasm Staging; Neoplastic Stem Cells; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins p21(ras); Receptor, ErbB-2; Signal Transduction; Tyrosine; Xenograft Model Antitumor Assays | 2015 |
Dasatinib promotes paclitaxel-induced necroptosis in lung adenocarcinoma with phosphorylated caspase-8 by c-Src.
Topics: A549 Cells; Adenocarcinoma; Adenocarcinoma of Lung; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Caspase 8; Cisplatin; Dasatinib; Disease-Free Survival; Drug Resistance, Neoplasm; Female; Humans; Kaplan-Meier Estimate; Lung Neoplasms; Male; Mice, Inbred BALB C; Mice, Nude; Middle Aged; Necrosis; Paclitaxel; Phosphorylation; Pregnancy; Protein Kinase Inhibitors; Proto-Oncogene Proteins pp60(c-src); Receptor-Interacting Protein Serine-Threonine Kinases; RNA Interference; Signal Transduction; Time Factors; Transfection; Treatment Outcome; Tyrosine; Xenograft Model Antitumor Assays | 2016 |
[Expression and activation of insulin receptor substrate-1 in endometrial carcinoma].
Topics: Adenocarcinoma; C-Peptide; Case-Control Studies; Endometrial Hyperplasia; Endometrial Neoplasms; Endometrium; Female; Humans; Insulin Receptor Substrate Proteins; Lymphatic Metastasis; Middle Aged; Neoplasm Staging; Phosphorylation; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tyrosine | 2008 |
Helicobacter pylori cytotoxin-associated gene A activates the signal transducer and activator of transcription 3 pathway in vitro and in vivo.
Topics: Adenocarcinoma; Animals; Antigens, Bacterial; Bacterial Proteins; Cell Line, Tumor; Cell Nucleus; Cytokine Receptor gp130; Gerbillinae; HeLa Cells; Helicobacter Infections; Helicobacter pylori; Humans; Male; Phosphorylation; Receptors, Interleukin-6; STAT3 Transcription Factor; Stomach Neoplasms; Transcription, Genetic; Tyrosine | 2009 |
A gamma-tocopherol-rich mixture of tocopherols inhibits colon inflammation and carcinogenesis in azoxymethane and dextran sulfate sodium-treated mice.
Topics: Adenocarcinoma; Adenoma; Animals; Antioxidants; Apoptosis; Azoxymethane; Carcinogens; Cell Transformation, Neoplastic; Cocarcinogenesis; Colon; Colonic Neoplasms; Dextran Sulfate; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; gamma-Tocopherol; Inflammation; Leukotriene B4; Male; Mice; Tyrosine | 2009 |
Hsp90 and a tyrosine embedded in the Hsp90 recognition loop are required for the Fer tyrosine kinase activity.
Topics: Adenocarcinoma; Amino Acid Motifs; Amino Acid Substitution; Animals; Binding Sites; Breast Neoplasms; Catalysis; Cell Line; Cell Line, Tumor; Epithelial Cells; Female; HSP90 Heat-Shock Proteins; Humans; Male; Mice; Mutagenesis, Site-Directed; Phosphorylation; Point Mutation; Prostatic Neoplasms; Protein Processing, Post-Translational; Protein-Tyrosine Kinases; Recombinant Fusion Proteins; Structure-Activity Relationship; Tyrosine | 2009 |
Immunohistochemical analysis of selected molecular markers in esophagus precancerous, adenocarcinoma and squamous cell carcinoma in Iranian subjects.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Barrett Esophagus; Biomarkers, Tumor; Carcinoma, Squamous Cell; Case-Control Studies; Cyclin-Dependent Kinase Inhibitor p21; Cyclooxygenase 2; Disease Progression; Esophageal Neoplasms; Esophagus; Female; Gastroesophageal Reflux; Glutathione S-Transferase pi; Humans; Immunohistochemistry; Iran; Male; Middle Aged; Precancerous Conditions; Tumor Suppressor Protein p53; Tyrosine; Young Adult | 2009 |
Science to practice: will randomized prospective clinical trials be necessary for RF ablation of large liver tumors with liposomal doxorubicin?
Topics: 8-Hydroxy-2'-Deoxyguanosine; Acetylcysteine; Adenocarcinoma; Aldehydes; Animals; Antibiotics, Antineoplastic; Apoptosis; Caspase 3; Catheter Ablation; Chemotherapy, Adjuvant; Combined Modality Therapy; Deoxyguanosine; DNA Damage; Doxorubicin; Histones; HSP70 Heat-Shock Proteins; Humans; Liver Neoplasms; Mammary Neoplasms, Experimental; Oxidative Stress; Prospective Studies; Randomized Controlled Trials as Topic; Rats; Tyrosine | 2010 |
A pilot study of preoperative gefitinib for early-stage lung cancer to assess intratumor drug concentration and pathways mediating primary resistance.
Topics: Adenocarcinoma; Aged; Antineoplastic Agents; Blotting, Western; Carcinoma, Squamous Cell; Drug Resistance, Neoplasm; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Female; Gefitinib; Humans; Lung Neoplasms; Male; Neoplasm Staging; Phosphorylation; Pilot Projects; Prognosis; Proto-Oncogene Proteins c-akt; Quinazolines; Signal Transduction; STAT3 Transcription Factor; Survival Rate; Tissue Distribution; Tyrosine | 2010 |
Clinical significance of simultaneous determination of serum tryptophan and tyrosine in patients with lung cancer.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Biomarkers, Tumor; Case-Control Studies; Chromatography, High Pressure Liquid; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Sensitivity and Specificity; Tryptophan; Tyrosine | 2011 |
Preparation and biological evaluation of 3-[(76)Br]bromo-α-methyl-L-tyrosine, a novel tyrosine analog for positron emission tomography imaging of tumors.
Topics: Adenocarcinoma; Animals; Biological Transport; Cell Line, Tumor; Colonic Neoplasms; Drug Design; Drug Stability; Humans; Male; Mice; Positron-Emission Tomography; Tyrosine | 2011 |
The number of Helicobacter pylori CagA EPIYA C tyrosine phosphorylation motifs influences the pattern of gastritis and the development of gastric carcinoma.
Topics: Adenocarcinoma; Adult; Amino Acid Motifs; Antigens, Bacterial; Bacterial Proteins; DNA, Bacterial; Female; Gastritis; Helicobacter Infections; Helicobacter pylori; Humans; Male; Middle Aged; Phosphorylation; Stomach Neoplasms; Tyrosine | 2012 |
Hsp90 inhibition overcomes HGF-triggering resistance to EGFR-TKIs in EGFR-mutant lung cancer by decreasing client protein expression and angiogenesis.
Topics: Adenocarcinoma; Animals; Apoptosis; Benzoquinones; Blotting, Western; Drug Resistance, Neoplasm; ErbB Receptors; Female; Hepatocyte Growth Factor; HSP90 Heat-Shock Proteins; Humans; Lactams, Macrocyclic; Lung Neoplasms; Mice; Mutation; Prognosis; Protein Kinase Inhibitors; Tyrosine; Xenograft Model Antitumor Assays | 2012 |
A novel variant of the RON receptor tyrosine kinase derived from colorectal carcinoma cells which lacks tyrosine phosphorylation but induces cell migration.
Topics: Adenocarcinoma; Alternative Splicing; Cell Movement; Colorectal Neoplasms; Genetic Variation; HCT116 Cells; HEK293 Cells; HT29 Cells; Humans; Phosphorylation; Receptor Protein-Tyrosine Kinases; Tyrosine | 2012 |
Identification of pY654-β-catenin as a critical co-factor in hypoxia-inducible factor-1α signaling and tumor responses to hypoxia.
Topics: Adenocarcinoma; Adenoma; Adenoma, Islet Cell; Animals; Antibodies, Neutralizing; beta Catenin; Cell Hypoxia; Cell Line, Tumor; Epithelial-Mesenchymal Transition; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Lung Neoplasms; Mice; Mice, Transgenic; Neuroendocrine Tumors; Phosphorylation; Reactive Oxygen Species; Signal Transduction; Smad2 Protein; src-Family Kinases; Tyrosine; Vascular Endothelial Growth Factor A | 2013 |
Proinflammatory cytokines block growth of breast cancer cells by impairing signals from a growth factor receptor.
Topics: Adenocarcinoma; Apoptosis; Breast Neoplasms; Cell Cycle; Cell Division; DNA, Neoplasm; Humans; Insulin Receptor Substrate Proteins; Insulin-Like Growth Factor I; Interleukin-1; Interleukin-6; Phosphoproteins; Phosphorylation; Receptor, IGF Type 1; Signal Transduction; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Tyrosine | 2002 |
Anchorage-independent phosphorylation of p130(Cas) protects lung adenocarcinoma cells from anoikis.
Topics: Adenocarcinoma; Animals; Anoikis; Apoptosis; Bronchi; Cell Line; Cell Survival; Crk-Associated Substrate Protein; Dogs; Dose-Response Relationship, Drug; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Humans; Immunoblotting; Lung Neoplasms; Neoplasm Metastasis; Phosphoproteins; Phosphorylation; Plasmids; Precipitin Tests; Protein-Tyrosine Kinases; Proteins; Retinoblastoma-Like Protein p130; Signal Transduction; src-Family Kinases; Transfection; Tumor Cells, Cultured; Tyrosine | 2002 |
The proteolytic processing of pro-platelet-derived growth factor-A at RRKR(86) by members of the proprotein convertase family is functionally correlated to platelet-derived growth factor-A-induced functions and tumorigenicity.
Topics: 3T3 Cells; Adenocarcinoma; Animals; Binding Sites; CHO Cells; Colonic Neoplasms; Cricetinae; Furin; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Mutagenesis, Site-Directed; Phosphorylation; Platelet-Derived Growth Factor; Polymerase Chain Reaction; Proprotein Convertase 5; Proprotein Convertases; Protein Precursors; Serine Endopeptidases; Serine Proteinase Inhibitors; Substrate Specificity; Subtilisins; Transfection; Tumor Cells, Cultured; Tyrosine | 2003 |
Epidermal growth factor increased the expression of alpha2beta1-integrin and modulated integrin-mediated signaling in human cervical adenocarcinoma cells.
Topics: Adenocarcinoma; Antibodies; Cell Movement; Cell Size; Collagen Type IV; Enzyme Inhibitors; Epidermal Growth Factor; ErbB Receptors; Female; Fibronectins; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Humans; Integrin alpha2beta1; Phosphorylation; Protein-Tyrosine Kinases; Pseudopodia; Signal Transduction; Tumor Cells, Cultured; Tyrosine; Uterine Cervical Neoplasms | 2003 |
CagA tyrosine phosphorylation in gastric epithelial cells caused by Helicobacter pylori in patients with gastric adenocarcinoma.
Topics: Adenocarcinoma; Amino Acid Sequence; Antigens, Bacterial; Bacterial Proteins; Cells, Cultured; DNA, Bacterial; Epithelial Cells; Genetic Variation; Helicobacter Infections; Helicobacter pylori; Humans; Molecular Sequence Data; Phosphorylation; Stomach; Stomach Neoplasms; Tyrosine | 2003 |
Stat5a is tyrosine phosphorylated and nuclear localized in a high proportion of human breast cancers.
Topics: Adenocarcinoma; Adult; Aged; Breast Neoplasms; Cell Differentiation; Cell Nucleus; DNA-Binding Proteins; Female; Humans; Microfilament Proteins; Milk Proteins; Muscle Proteins; Phosphorylation; STAT3 Transcription Factor; STAT5 Transcription Factor; Trans-Activators; Tumor Suppressor Proteins; Tyrosine | 2004 |
Inhibition of SRC tyrosine kinase impairs inherent and acquired gemcitabine resistance in human pancreatic adenocarcinoma cells.
Topics: Adenocarcinoma; Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Apoptosis; Blotting, Northern; Blotting, Western; Caspases; Cell Cycle Proteins; Cell Division; Cell Line, Tumor; Cell Nucleus; Deoxycytidine; DNA-Binding Proteins; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; E2F Transcription Factors; E2F1 Transcription Factor; Gemcitabine; Genes, Dominant; Humans; Inhibitory Concentration 50; Mice; Mice, Nude; Neoplasm Metastasis; Neoplasm Transplantation; Pancreatic Neoplasms; Phosphorylation; Pyrimidines; Ribonucleoside Diphosphate Reductase; src-Family Kinases; Transcription Factors; Tyrosine | 2004 |
Decreased Helicobacter pylori associated gastric carcinogenesis in mice lacking inducible nitric oxide synthase.
Topics: Adenocarcinoma; Adenoma; Animals; Cell Transformation, Neoplastic; Gastric Mucosa; Gastritis; Helicobacter Infections; Helicobacter pylori; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Stomach; Stomach Neoplasms; Tyrosine | 2004 |
Sequential observations on the occurrence of preneoplastic and neoplastic lesions in mouse colon treated with azoxymethane and dextran sodium sulfate.
Topics: Adenocarcinoma; Animals; Azoxymethane; Carcinogens; Colitis; Colon; Colonic Neoplasms; Dextran Sulfate; Immunoenzyme Techniques; Incidence; Injections, Intraperitoneal; Intestinal Mucosa; Male; Mice; Mice, Inbred ICR; Precancerous Conditions; Tyrosine | 2004 |
Anticancer effects of ZD6474, a VEGF receptor tyrosine kinase inhibitor, in gefitinib ("Iressa")-sensitive and resistant xenograft models.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Proliferation; Drug Resistance, Neoplasm; Enzyme Inhibitors; Female; Gefitinib; Lung Neoplasms; Mice; Mice, Nude; Neovascularization, Pathologic; Phosphorylation; Piperidines; Quinazolines; Receptors, Vascular Endothelial Growth Factor; Tumor Cells, Cultured; Tyrosine; Xenograft Model Antitumor Assays | 2004 |
Breast adenocarcinoma cell adhesion to the vascular subendothelium in whole blood and under flow conditions: effects of alphavbeta3 and alphaIIbbeta3 antagonists.
Topics: Abciximab; Acetates; Adenocarcinoma; Antibodies, Monoclonal; Blood Platelets; Blood Vessels; Breast Neoplasms; Cell Adhesion; Endothelium, Vascular; Extracellular Matrix; Female; Humans; Immunoglobulin Fab Fragments; Integrin alphaVbeta3; Platelet Adhesiveness; Platelet Aggregation Inhibitors; Platelet Glycoprotein GPIIb-IIIa Complex; Pyridines; Receptors, Vitronectin; Regional Blood Flow; Tumor Cells, Cultured; Tyrosine | 2004 |
Farnesyl transferase inhibitor (R115777)-induced inhibition of STAT3(Tyr705) phosphorylation in human pancreatic cancer cell lines require extracellular signal-regulated kinases.
Topics: Adenocarcinoma; Alkyl and Aryl Transferases; Cell Cycle Proteins; Cell Growth Processes; Cyclin-Dependent Kinase Inhibitor p21; DNA-Binding Proteins; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Farnesyltranstransferase; Humans; Interleukin-6; Pancreatic Neoplasms; Phosphorylation; Proto-Oncogene Proteins c-myc; Quinolones; Serine; STAT3 Transcription Factor; Trans-Activators; Tyrosine; Up-Regulation | 2005 |
Boosting antitumor responses of T lymphocytes infiltrating human prostate cancers.
Topics: Adenocarcinoma; Animals; Arginase; Arginine; CD8-Positive T-Lymphocytes; Cell Line, Tumor; Humans; Interferon-gamma; Lymphocyte Count; Lymphocytes, Tumor-Infiltrating; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Nitric Oxide Synthase; Organ Culture Techniques; Prostatic Neoplasms; T-Lymphocyte Subsets; Tyrosine | 2005 |
Inducible nitric oxide synthase, nitrotyrosine and apoptosis in gastric adenocarcinomas and their correlation with a poor survival.
Topics: Adenocarcinoma; Adult; Aged; Apoptosis; Female; Humans; Male; Middle Aged; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Stomach Neoplasms; Survival Analysis; Tyrosine | 2005 |
Expression of beta-catenin is regulated by PI-3 kinase and sodium butyrate in colorectal cancer cells.
Topics: Adenocarcinoma; Alkaline Phosphatase; Androstadienes; beta Catenin; Butyrates; Cell Line, Tumor; Colorectal Neoplasms; Humans; Immunohistochemistry; Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Ribosomal Protein S6 Kinases; Ribosomal Protein S6 Kinases, 70-kDa; Serine; Signal Transduction; Tyrosine; Wortmannin | 2006 |
High expression of ErbB family members and their ligands in lung adenocarcinomas that are sensitive to inhibition of epidermal growth factor receptor.
Topics: Adenocarcinoma; Adenocarcinoma, Bronchiolo-Alveolar; Animals; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Drug Resistance, Neoplasm; ErbB Receptors; Gefitinib; Genes, ras; Humans; Ligands; Lung Neoplasms; Mice; Mice, Knockout; Mutation; Neoplasms, Glandular and Epithelial; Phosphorylation; Proto-Oncogene Proteins c-akt; Quinazolines; Receptor, ErbB-2; Receptor, ErbB-3; Tumor Cells, Cultured; Tyrosine | 2005 |
Differences in oxidative stress dependence between gastric adenocarcinoma subtypes.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Biomarkers; Carcinoma in Situ; Deoxyguanine Nucleotides; DNA, Neoplasm; Female; Gastric Mucosa; Humans; Immunohistochemistry; Male; Middle Aged; Neoplasm Proteins; Nitric Oxide; Nitric Oxide Synthase Type II; Oxidative Stress; Precancerous Conditions; Retrospective Studies; Stomach Neoplasms; Tyrosine | 2006 |
gamma-Tocotrienol inhibits ErbB3-dependent PI3K/Akt mitogenic signalling in neoplastic mammary epithelial cells.
Topics: Adenocarcinoma; alpha-Tocopherol; Animals; Cell Line, Tumor; Cell Survival; Chromans; Epithelial Cells; Female; Mammary Neoplasms, Animal; Mice; Mice, Inbred BALB C; Mitosis; Phosphatidylinositol 3-Kinases; Phosphorylation; Proto-Oncogene Proteins c-akt; Receptor, ErbB-3; Signal Transduction; Tyrosine; Vitamin E; Vitamins | 2006 |
Helicobacter pylori CagA interacts with E-cadherin and deregulates the beta-catenin signal that promotes intestinal transdifferentiation in gastric epithelial cells.
Topics: Adenocarcinoma; Antigens, Bacterial; Bacterial Proteins; beta Catenin; Cadherins; Cell Line; Cell Nucleus; Cell Transformation, Neoplastic; Cyclin-Dependent Kinase Inhibitor p21; Cytoplasm; Gastric Mucosa; Gene Expression Regulation, Neoplastic; Homeodomain Proteins; Humans; Intestinal Mucosa; Mucin-2; Mucins; Phosphorylation; Precancerous Conditions; Stomach Neoplasms; Transcriptional Activation; Tyrosine | 2007 |
Epidermal growth factor (EGF) activates nuclear factor-kappaB through IkappaBalpha kinase-independent but EGF receptor-kinase dependent tyrosine 42 phosphorylation of IkappaBalpha.
Topics: Adenocarcinoma; Carcinoma, Non-Small-Cell Lung; Cell Nucleus; Enzyme Activation; Epidermal Growth Factor; ErbB Receptors; Humans; I-kappa B Kinase; NF-kappa B; Phosphorylation; Tumor Necrosis Factor-alpha; Tyrosine; Ubiquitination | 2007 |
Platelet-derived growth factor receptor beta-mediated phosphorylation of MUC1 enhances invasiveness in pancreatic adenocarcinoma cells.
Topics: Adenocarcinoma; Amino Acid Motifs; Amino Acid Sequence; Animals; Antigens, Neoplasm; beta Catenin; Binding Sites; Cell Line, Tumor; Cell Nucleus; Female; Humans; Mass Spectrometry; Mice; Mice, Nude; Molecular Sequence Data; Mucin-1; Mucins; Neoplasm Invasiveness; Pancreatic Neoplasms; Phosphorylation; Receptor, Platelet-Derived Growth Factor beta; Tyrosine | 2007 |
Low expression of ORF4, a dominant negative variant of peroxisome proliferator-activated receptor gamma, in colorectal adenocarcinoma.
Topics: Adenocarcinoma; Aged; Aged, 80 and over; Alternative Splicing; Caco-2 Cells; Cell Line, Tumor; Colorectal Neoplasms; Female; Gene Expression Regulation, Neoplastic; HT29 Cells; Humans; Male; Middle Aged; Oxazoles; PPAR gamma; Protein Isoforms; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tyrosine | 2007 |
Inducible nitric oxide synthase, nitrotyrosine and p53 mutations in the molecular pathogenesis of Barrett's esophagus and esophageal adenocarcinoma.
Topics: Adenocarcinoma; Adolescent; Adult; Aged; Aged, 80 and over; Barrett Esophagus; Chronic Disease; Esophageal Neoplasms; Female; Genes, p53; Humans; Inflammation Mediators; Male; Middle Aged; Nitric Oxide; Nitric Oxide Synthase Type II; Point Mutation; Tumor Suppressor Protein p53; Tyrosine | 2008 |
Constitutive activation of c-Met is correlated with c-Met overexpression and dependent on cell-matrix adhesion in lung adenocarcinoma cell lines.
Topics: Acetylcysteine; Adenocarcinoma; Animals; Antibodies; Blotting, Western; Cadherins; Cell Adhesion; Cell Line, Tumor; Culture Media, Conditioned; DNA, Neoplasm; Dogs; Down-Regulation; Extracellular Matrix; Hepatocyte Growth Factor; Humans; Lung Neoplasms; Oligonucleotide Array Sequence Analysis; Phosphorylation; Polymorphism, Single Nucleotide; Proto-Oncogene Proteins c-met; Tyrosine | 2008 |
mAtNOS1 induces apoptosis of human mammary adenocarcinoma cells.
Topics: Adenocarcinoma; Apoptosis; Arabidopsis Proteins; Breast Neoplasms; Calcium; Cell Line, Tumor; Cytochromes c; Female; Humans; Immunochemistry; Mitochondria; Nitric Oxide; Nitric Oxide Synthase; Transfection; Tyrosine | 2008 |
Activation of a tumor-associated protein kinase (p40TAK) and casein kinase 2 in human squamous cell carcinomas and adenocarcinomas of the lung.
Topics: Adenocarcinoma; Amino Acid Sequence; Antibodies; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Casein Kinases; Caseins; Chromatography, Ion Exchange; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Humans; Kinetics; Lung; Lung Neoplasms; Molecular Sequence Data; Myelin Basic Protein; Peptides; Phosphoserine; Phosphothreonine; Phosphotyrosine; Protein Kinases; Protein Serine-Threonine Kinases; Ribosomal Protein S6; Ribosomal Proteins; Substrate Specificity; Tyrosine | 1994 |
Enhanced phosphoinositide metabolism in colorectal carcinoma cells derived from familial adenomatous polyposis patients.
Topics: Adenocarcinoma; Adenomatous Polyposis Coli; Cell Line; Chromatography, Affinity; Colorectal Neoplasms; Diglycerides; Electrophoresis, Polyacrylamide Gel; Gene Expression; Humans; Inositol 1,4,5-Trisphosphate; Isoenzymes; Phosphatidylinositols; Phosphoproteins; Phosphorylation; Phosphotyrosine; RNA, Messenger; Second Messenger Systems; Tumor Cells, Cultured; Type C Phospholipases; Tyrosine | 1994 |
Tyrosine kinase activity is necessary for growth factor-stimulated rabbit type II pneumocyte proliferation.
Topics: Adenocarcinoma; Animals; Blotting, Western; Catechols; Cell Division; Cell Line; Cells, Cultured; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Genistein; Humans; Isoflavones; Kinetics; Lung; Male; Molecular Weight; Nitriles; Phosphoproteins; Phosphotyrosine; Protein-Tyrosine Kinases; Rabbits; Transforming Growth Factor alpha; Tumor Cells, Cultured; Tyrosine; Tyrphostins | 1994 |
[The expression of C-FOS, C-JUN and phosphotyrosine gene products in lung cancer].
Topics: Adenocarcinoma; Carcinoma, Squamous Cell; Gene Expression; Humans; Lung Neoplasms; Phosphotyrosine; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Tyrosine | 1994 |
Treatment of Wistar rats with a renal carcinogen, ferric nitrilotriacetate, causes DNA-protein cross-linking between thymine and tyrosine in their renal chromatin.
Topics: Adenocarcinoma; Animals; Carcinogens; Chromatin; Cross-Linking Reagents; DNA Damage; DNA, Neoplasm; Ferric Compounds; Kidney; Kidney Neoplasms; Kidney Tubules, Proximal; Male; Neoplasm Proteins; Nitrilotriacetic Acid; Rats; Rats, Wistar; Thymine; Tyrosine | 1995 |
Identification of protein-tyrosine kinase genes preferentially expressed in embryo stomach and gastric cancer.
Topics: Adenocarcinoma; Aging; Amino Acid Sequence; Animals; Base Sequence; Blotting, Northern; DNA; DNA, Neoplasm; Embryonic and Fetal Development; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Gene Library; Humans; Molecular Sequence Data; Open Reading Frames; Phosphotyrosine; Poly A; Protein-Tyrosine Kinases; Rats; Rats, Wistar; RNA; RNA, Messenger; Sequence Homology, Amino Acid; Sequence Homology, Nucleic Acid; Stomach; Stomach Neoplasms; Tyrosine | 1993 |
Inhibition of ribonucleotide reductase by nitric oxide derived from thionitrites: reversible modifications of both subunits.
Topics: Adenocarcinoma; Animals; Cell Line; Cysteine; Electron Spin Resonance Spectroscopy; Escherichia coli; Free Radicals; Kinetics; Leukemia L1210; Macromolecular Substances; Mice; Nitric Oxide; Nitrites; Ribonucleotide Reductases; Spectrophotometry; Tumor Cells, Cultured; Tyrosine | 1995 |
Decreased tyrosine phosphorylation in tumour cells resistant to FCE 24517 (tallimustine).
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Colonic Neoplasms; Distamycins; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Enzyme Inhibitors; Humans; Leukemia L1210; Mice; Neoplasm Proteins; Nitrogen Mustard Compounds; Phosphorylation; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Sensitivity and Specificity; Tumor Cells, Cultured; Tyrosine; Vanadates | 1995 |
Helicobacter pylori attachment to gastric cells induces cytoskeletal rearrangements and tyrosine phosphorylation of host cell proteins.
Topics: Adenocarcinoma; Bacterial Adhesion; Cell Line; Cytoskeletal Proteins; Cytoskeleton; Escherichia coli; Fluorescent Antibody Technique; Helicobacter pylori; Humans; Microscopy, Confocal; Microscopy, Electron; Microscopy, Immunoelectron; Microvilli; Phosphoproteins; Phosphorylation; Phosphotyrosine; Stomach Neoplasms; Tumor Cells, Cultured; Tyrosine | 1996 |
Inhibition of in vitro tumor cell invasion by ginsenoside Rg3.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Carbohydrate Sequence; Carcinoma, Small Cell; Ginsenosides; Humans; Liver Neoplasms, Experimental; Lung Neoplasms; Lysophospholipids; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Neoplasm Invasiveness; Neoplasm Metastasis; Neoplasm Proteins; Pancreatic Neoplasms; Phosphorylation; Rats; Rats, Inbred Strains; Saponins; Tyrosine | 1996 |
A 100-kDa protein tyrosine phosphorylation is concurrent with beta 1 integrin-mediated morphological differentiation in neuroblastoma and small cell lung cancer cells.
Topics: Adenocarcinoma; Benzoquinones; Blotting, Western; Carcinoma, Small Cell; Cell Adhesion; Cell Adhesion Molecules; Cell Differentiation; Enzyme Inhibitors; Flow Cytometry; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Humans; Integrin beta1; Lactams, Macrocyclic; Lung Neoplasms; Neuroblastoma; Phosphorylation; Protein-Tyrosine Kinases; Quinones; Receptor, Insulin; Rifabutin; Signal Transduction; Tumor Cells, Cultured; Tyrosine | 1996 |
Leptin induces tyrosine phosphorylation of cellular proteins including STAT-1 in human renal adenocarcinoma cells, ACHN.
Topics: Adenocarcinoma; Blotting, Western; DNA-Binding Proteins; Humans; Kidney Neoplasms; Leptin; Obesity; Phosphorylation; Proteins; Recombinant Proteins; STAT1 Transcription Factor; Trans-Activators; Tumor Cells, Cultured; Tyrosine | 1996 |
Interferon-alpha and -gamma inhibit the growth and neoplastic potential of v-src-transformed human epithelial cells by reducing Src tyrosine kinase activity.
Topics: Adenocarcinoma; Antineoplastic Agents; Cell Line, Transformed; Epithelial Cells; Gallbladder Neoplasms; Genes, ras; Genes, src; Humans; Interferon-alpha; Interferon-gamma; Phosphorylation; Protein-Tyrosine Kinases; src-Family Kinases; Transfection; Tyrosine | 1998 |
Studies of iron deposits, inducible nitric oxide synthase and nitrotyrosine in a rat model for esophageal adenocarcinoma.
Topics: Adenocarcinoma; Anastomosis, Surgical; Animals; Barrett Esophagus; Duodenum; Esophageal Neoplasms; Esophagus; Iron; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitro Compounds; Rats; Rats, Sprague-Dawley; Tyrosine | 1998 |
Cytoplasmic redistribution of E-cadherin-catenin adhesion complex is associated with down-regulated tyrosine phosphorylation of E-cadherin in human bronchopulmonary carcinomas.
Topics: Adenocarcinoma; alpha Catenin; beta Catenin; Cadherins; Carcinoma, Bronchogenic; Carcinoma, Squamous Cell; Cytoskeletal Proteins; Down-Regulation; Humans; Lung Neoplasms; Macromolecular Substances; Neoplasm Invasiveness; Phosphorylation; Trans-Activators; Tumor Cells, Cultured; Tyrosine | 1998 |
Gap junctional communication and the tyrosine phosphorylation of connexin 43 in interaction between breast cancer and endothelial cells.
Topics: Adenocarcinoma; Breast Neoplasms; Cell Adhesion; Cell Line; Connexin 43; Endothelium, Vascular; Female; Gap Junctions; Humans; Phosphorylation; Tumor Cells, Cultured; Tyrosine | 1998 |
Rapid adhesion and spread of non-adherent colon cancer Colo201 cells induced by the protein kinase inhibitors, K252a and KT5720 and suppression of the adhesion by the immunosuppressants FK506 and cyclosporin A.
Topics: Adenocarcinoma; Carbazoles; Cell Adhesion; Cell Adhesion Molecules; Colonic Neoplasms; Cyclosporine; Cytoskeletal Proteins; Enzyme Inhibitors; Extracellular Matrix; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Humans; Immunosuppressive Agents; Indole Alkaloids; Indoles; Integrins; Neoplasm Metastasis; Paxillin; Phosphoproteins; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Pyrroles; Sulfonamides; Tacrolimus; Tumor Cells, Cultured; Tyrosine | 1998 |
Association of increased immunostaining for inducible nitric oxide synthase and nitrotyrosine with fibroblast growth factor transformation in pancreatic cancer.
Topics: Adenocarcinoma; Aged; Aged, 80 and over; Fibroblast Growth Factors; Humans; Immunohistochemistry; Nitric Oxide Synthase; Pancreatic Neoplasms; Retrospective Studies; Tyrosine | 1999 |
Nitric oxide synthase expression and nitric oxide production in human colon carcinoma tissue.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Colonic Neoplasms; Female; Humans; Immunohistochemistry; Male; Middle Aged; Nitric Oxide; Nitric Oxide Synthase; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sigmoid Neoplasms; Tyrosine | 1999 |
Prolactin gene-disruption arrests mammary gland development and retards T-antigen-induced tumor growth.
Topics: Adenocarcinoma; Animals; Antigens, Polyomavirus Transforming; DNA-Binding Proteins; Female; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice; Mice, Mutant Strains; Mice, Transgenic; Milk Proteins; Phosphorylation; Pituitary Gland; Pregnancy; Prolactin; STAT1 Transcription Factor; STAT5 Transcription Factor; Trans-Activators; Tyrosine | 2000 |
Tyrosine nitration of c-SRC tyrosine kinase in human pancreatic ductal adenocarcinoma.
Topics: Adenocarcinoma; Blotting, Western; Chromatography, High Pressure Liquid; Cortactin; Humans; Microfilament Proteins; Nitrates; Pancreatic Neoplasms; Phosphorylation; Phosphotyrosine; Precipitin Tests; Protein Conformation; Protein Folding; Proto-Oncogene Proteins pp60(c-src); Tumor Cells, Cultured; Tyrosine | 2000 |
Localization of antioxidant enzymes and oxidative damage products in normal and malignant prostate epithelium.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Adenocarcinoma; Antibodies, Monoclonal; Antioxidants; Bone Neoplasms; Catalase; Deoxyguanosine; Glutathione Peroxidase; Humans; Immunoenzyme Techniques; Lipofuscin; Male; Prostate; Prostatic Neoplasms; Reactive Oxygen Species; Superoxide Dismutase; Tyrosine | 2000 |
A novel germ line juxtamembrane Met mutation in human gastric cancer.
Topics: 3T3 Cells; Adenocarcinoma; Amino Acid Sequence; Animals; Cell Membrane; DNA, Neoplasm; Exons; Female; Gene Amplification; Gene Expression Regulation, Neoplastic; Germ-Line Mutation; Hepatocyte Growth Factor; Humans; Mice; Mice, Nude; Molecular Sequence Data; Mutation, Missense; Phosphorylation; Protein Structure, Tertiary; Proto-Oncogene Proteins c-met; Stomach Neoplasms; Tyrosine | 2000 |
Increased expression of the interleukin-11 receptor and evidence of STAT3 activation in prostate carcinoma.
Topics: Adenocarcinoma; Blotting, Western; Cell Line; DNA-Binding Proteins; Gene Expression Regulation, Neoplastic; Humans; Hyperplasia; Immunohistochemistry; Interleukin-11; Interleukin-11 Receptor alpha Subunit; Male; Phosphorylation; Prostate; Prostatic Neoplasms; Receptors, Interleukin; Receptors, Interleukin-11; RNA, Messenger; STAT3 Transcription Factor; Trans-Activators; Tumor Cells, Cultured; Tyrosine | 2001 |
Tyrosine kinase-dependent, phosphatidylinositol 3'-kinase, and mitogen-activated protein kinase-independent signaling pathways prevent lung adenocarcinoma cells from anoikis.
Topics: Adenocarcinoma; Anoikis; Cell Adhesion; Cell Survival; Enzyme Inhibitors; Genistein; Humans; Lung Neoplasms; MAP Kinase Signaling System; Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Substrate Specificity; Tumor Cells, Cultured; Tyrosine | 2001 |
c-MET expression in myofibroblasts: role in autocrine activation and prognostic significance in lung adenocarcinoma.
Topics: Adenocarcinoma; Autocrine Communication; Cell Line; Computer Systems; Dissection; Fibroblasts; Hepatocyte Growth Factor; Humans; Lasers; Lung Neoplasms; Muscle, Smooth; Phosphorylation; Prognosis; Proto-Oncogene Proteins c-met; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tyrosine | 2001 |
Enhanced vascular permeability in solid tumor involving peroxynitrite and matrix metalloproteinases.
Topics: Adenocarcinoma; Animals; Azoles; Bradykinin; Capillary Permeability; Collagenases; Colonic Neoplasms; Dose-Response Relationship, Drug; Enzyme Precursors; Free Radical Scavengers; Gelatinases; Guinea Pigs; Isoindoles; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Matrix Metalloproteinase Inhibitors; Metalloendopeptidases; Mice; Mice, Inbred C57BL; Nitrates; Oligopeptides; Organoselenium Compounds; Protease Inhibitors; Sarcoma 180; Skin; Tyrosine; Uric Acid | 2001 |
Immunotherapy of C3H/HeJ mammary adenocarcinoma with interleukin-2, mistletoe lectin or their combination. effects on tumour growth, capillary leakage and nitric oxide (NO) production.
Topics: Adenocarcinoma; Adjuvants, Immunologic; Animals; Capillary Permeability; Female; Interleukin-2; Kidney; Lung Neoplasms; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C3H; Neoplasm Transplantation; Nitric Oxide; Plant Preparations; Plant Proteins; Pleural Effusion, Malignant; Recombinant Proteins; Ribosome Inactivating Proteins, Type 2; Toxins, Biological; Tumor Cells, Cultured; Tyrosine | 2001 |
Phosphorylation of tyrosine 972 of the Helicobacter pylori CagA protein is essential for induction of a scattering phenotype in gastric epithelial cells.
Topics: Adenocarcinoma; Antigens, Bacterial; Bacterial Proteins; Epithelial Cells; Gastric Mucosa; Helicobacter Infections; Helicobacter pylori; Humans; Immunoblotting; Microscopy, Confocal; Phenotype; Phosphorylation; Stomach Neoplasms; Tumor Cells, Cultured; Tyrosine; Virulence | 2001 |
FGF-1 and FGF-2 regulate the expression of E-cadherin and catenins in pancreatic adenocarcinoma.
Topics: Adenocarcinoma; alpha Catenin; beta Catenin; Cadherins; Cell Communication; Cytoskeletal Proteins; Fibroblast Growth Factor 1; Fibroblast Growth Factor 2; Humans; Pancreatic Neoplasms; Phosphorylation; Trans-Activators; Tumor Cells, Cultured; Tyrosine | 2001 |
Comparative somatostatin receptor scintigraphy using in-111-DOTA-lanreotide and in-111-DOTA-Tyr3-octreotide versus F-18-FDG-PET for evaluation of somatostatin receptor-mediated radionuclide therapy.
Topics: Adenocarcinoma; Adult; Carcinoid Tumor; Fluorodeoxyglucose F18; Heterocyclic Compounds; Humans; Intestinal Neoplasms; Ligands; Lung Neoplasms; Lymphoma; Neuroendocrine Tumors; Octreotide; Peptides, Cyclic; Radiopharmaceuticals; Receptors, Somatostatin; Tomography, Emission-Computed; Tyrosine | 2001 |
Rho family GTPases regulate mammary epithelium cell growth and metastasis through distinguishable pathways.
Topics: Adenocarcinoma; Animals; cdc42 GTP-Binding Protein; Cell Division; Chemotaxis; Epidermal Growth Factor; Epithelium; Lung Neoplasms; Mammary Neoplasms, Experimental; Multigene Family; Rats; rho GTP-Binding Proteins; Signal Transduction; Stress Fibers; Transfection; Tumor Cells, Cultured; Tyrosine | 2001 |
Peroxynitrite-mediated stress is associated with proliferation of human metastatic colorectal carcinoma in the liver.
Topics: Adenocarcinoma; Aged; Apoptosis; Cell Division; Colorectal Neoplasms; Female; Humans; Immunoenzyme Techniques; Liver Neoplasms; Male; Middle Aged; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Oxidants; Oxidative Stress; Proliferating Cell Nuclear Antigen; Reactive Oxygen Species; Tyrosine | 2002 |
ErbB-beta-catenin complexes are associated with human infiltrating ductal breast and murine mammary tumor virus (MMTV)-Wnt-1 and MMTV-c-Neu transgenic carcinomas.
Topics: Adenocarcinoma; Animals; beta Catenin; Breast Neoplasms; Cytoskeletal Proteins; ErbB Receptors; Humans; Immunoblotting; Immunohistochemistry; Ligands; Mammary Tumor Virus, Mouse; Mice; Mice, Transgenic; Microscopy, Fluorescence; Phosphorylation; Precipitin Tests; Protein Binding; Proto-Oncogene Proteins; Receptor, ErbB-2; Signal Transduction; Trans-Activators; Tumor Cells, Cultured; Tyrosine; Wnt Proteins; Wnt1 Protein; Zebrafish Proteins | 2002 |
Diagnosis of pancreatic disease by a synthetic peptide. A new test of exocrine pancreatic function.
Topics: 4-Aminobenzoic Acid; Adenocarcinoma; Adult; Aminobenzoates; Chronic Disease; Dipeptides; Female; Humans; Male; Middle Aged; Pancreas; Pancreatic Neoplasms; Pancreatitis; para-Aminobenzoates; Tyrosine | 1976 |
Transfer RNA species in tumors of different growth rates.
Topics: Adenocarcinoma; Animals; Cell Division; Female; Histidine; Liver; Lymphoma; Lysine; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice; Mice, Inbred DBA; Neoplasms, Experimental; Phenylalanine; RNA, Neoplasm; RNA, Transfer; Time Factors; Tyrosine | 1976 |
Ligand-induced activation of epidermal growth factor receptor in intact rat mammary adenocarcinoma cells without detectable receptor phosphorylation.
Topics: Adenocarcinoma; Animals; Autoradiography; Blotting, Northern; Blotting, Western; Cell Membrane; Cross-Linking Reagents; ErbB Receptors; Ligands; Mammary Neoplasms, Experimental; Phosphorylation; Precipitin Tests; Protein-Tyrosine Kinases; Rats; RNA, Neoplasm; Substrate Specificity; Tumor Cells, Cultured; Tyrosine | 1992 |
Early loss of the tyrosyl radical in ribonucleotide reductase of adenocarcinoma cells producing nitric oxide.
Topics: Adenocarcinoma; Amino Acid Oxidoreductases; Animals; Arginine; Blotting, Western; Citrulline; Electron Spin Resonance Spectroscopy; Enzyme Induction; Free Radicals; Kinetics; Mammary Neoplasms, Experimental; Mice; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Nitroarginine; Ribonucleotide Reductases; Tumor Cells, Cultured; Tyrosine | 1992 |
Enhancement by tyrosine methyl ester of gastric carcinogenesis induced by N-methyl-N'-nitro-N-nitrosoguanidine in Wistar rats.
Topics: Adenocarcinoma; Animals; Catecholamines; Drug Synergism; Epinephrine; Gastric Acidity Determination; Gastric Mucosa; Gastrins; Male; Methylnitronitrosoguanidine; Muscle, Smooth; Norepinephrine; Rats; Rats, Inbred Strains; Stomach; Stomach Neoplasms; Tyrosine | 1991 |
Analysis of pp60c-src tyrosine kinase activity and phosphotyrosyl phosphatase activity in human colon carcinoma and normal human colon mucosal cells.
Topics: Adenocarcinoma; Buffers; Cells, Cultured; Colonic Neoplasms; Humans; Immunologic Techniques; Intestinal Mucosa; Oncogene Protein pp60(v-src); Peptide Mapping; Phosphoprotein Phosphatases; Phosphotyrosine; Protein Tyrosine Phosphatases; Protein-Tyrosine Kinases; Retroviridae Proteins; Tyrosine; Vanadates | 1987 |
Tyrosine-rich crystalloids in neoplasms and tissues of the head and neck.
Topics: Adenocarcinoma; Adolescent; Adult; Aged; Female; Head and Neck Neoplasms; Humans; Laryngeal Neoplasms; Male; Microscopy, Electron; Middle Aged; Parotid Neoplasms; Salivary Gland Neoplasms; Tyrosine | 1986 |
Tumor response to phenylalanine-tyrosine-limited diets.
Topics: Adenocarcinoma; Amino Acids; Animals; Carcinoma, Hepatocellular; Cystadenoma; Deficiency Diseases; Diet Therapy; Female; Humans; Liver Neoplasms; Mammary Neoplasms, Experimental; Mice; Middle Aged; Neoplasms, Experimental; Ovarian Neoplasms; Phenylalanine; Sarcoma, Experimental; Tyrosine | 1969 |
[Effect of 5-fluorouracil on protein metabolism of tumors and normal tissues in culture].
Topics: Adenocarcinoma; Animals; Autoradiography; Carcinoma, Basal Cell; Cell Line; Cell Transformation, Neoplastic; Culture Techniques; Depression, Chemical; Fluorouracil; Haplorhini; Humans; Kidney; Leucine; Neoplasm Proteins; Protein Biosynthesis; Simian virus 40; Skin; Tritium; Tyrosine | 1970 |
Quantitative effects of nutritional essential amino acid deficiency upon immune responses to tumors in mice.
Topics: Adenocarcinoma; Amino Acids; Animals; Antibodies, Neoplasm; Antigen-Antibody Complex; Arginine; Cells, Cultured; Cysteine; Cytotoxicity Tests, Immunologic; Deficiency Diseases; Diet; Histidine; Immunity, Cellular; Isoleucine; Lysine; Male; Mammary Neoplasms, Experimental; Methionine; Mice; Mice, Inbred C3H; Mice, Inbred CBA; Phenylalanine; Threonine; Time Factors; Tryptophan; Tyrosine; Valine | 1973 |
Identification of melanoma cells by formaldehyde-induced fluorescence.
Topics: Adenocarcinoma; Cell Line; Culture Techniques; Cysteine; Dopamine; Fluorescence; Formaldehyde; HeLa Cells; Humans; Melanoma; Tyrosine; Ultraviolet Rays | 1974 |
Radiochemical assays for p-hydroxyphenylpyruvate hydroxylase activity in human liver.
Topics: Adenocarcinoma; Amino Acid Oxidoreductases; Carbon Dioxide; Carbon Isotopes; Cholecystitis; Chromatography, Thin Layer; Cold Temperature; Drug Stability; Homogentisic Acid; Humans; Hydrogen-Ion Concentration; Kinetics; Liver; Liver Cirrhosis; Liver Neoplasms; Methods; Mixed Function Oxygenases; Phenylpyruvic Acids; Statistics as Topic; Stomach Neoplasms; Tyrosine | 1971 |
Effect of essential amino acid restriction on the growth of female C57BL mice and their implanted BW10232 adenocarcinomas.
Topics: Adenocarcinoma; Amino Acids; Animals; Body Weight; Deficiency Diseases; Female; Isoleucine; Leucine; Lysine; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Phenylalanine; Rats; Threonine; Transplantation, Homologous; Tryptophan; Tyrosine; Valine | 1971 |