tyrosine and Acute Confusional Senile Dementia

Topics: Alzheimer Disease; Humans; Microglia; Parkinson Disease; Protein-Tyrosine Kinases; src-Family Kinases; Tyrosine

Topics: Alzheimer Disease; Brain; Humans; Phosphorylation; Protein Tyrosine Phosphatases, Non-Receptor; Signal Transduction; Tyrosine

Topics: Alzheimer Disease; Amyotrophic Lateral Sclerosis; Biomarkers; Humans; Huntington Disease; Parkinson Disease; Prion Diseases; Tyrosine

Topics: Alzheimer Disease; Amino Acid Sequence; Animals; Humans; Microtubules; Molecular Sequence Data; Phosphorylation; Proto-Oncogene Proteins c-fyn; tau Proteins; Tauopathies; Tyrosine

Topics: Aldehydes; Alzheimer Disease; Brain; Disease Progression; Humans; Nerve Tissue Proteins; Oxidation-Reduction; Oxidative Stress; Tyrosine

Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Ascorbic Acid; Copper; Histidine; Humans; Hydroxyl Radical; Hydroxylation; Oxidation-Reduction; Peptide Fragments; Tyrosine

Topics: Adaptor Proteins, Signal Transducing; Alzheimer Disease; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Brain; Endopeptidases; GRB2 Adaptor Protein; Humans; Models, Neurological; Phosphorylation; Protein Binding; src Homology Domains; Tyrosine

Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Chelating Agents; Curcumin; DNA; Enzyme Inhibitors; Ginkgo biloba; Humans; Lipid Peroxidation; Metals; Oxidation-Reduction; Oxygen; Oxygen Consumption; Peptides; Plant Extracts; Reactive Oxygen Species; Tyrosine

Topics: Alzheimer Disease; Amino Acids; Choline; Choline O-Acetyltransferase; Diabetes Mellitus; Dopa Decarboxylase; Humans; Intellectual Disability; Memory; Myasthenia Gravis; Neurotransmitter Agents; Nutritional Physiological Phenomena; Serotonin; Tryptophan; Tyrosine

Topics: Alzheimer Disease; DNA Damage; Free Radicals; Glycation End Products, Advanced; Humans; Lipid Peroxidation; Models, Neurological; Neurofilament Proteins; Oxidative Stress; RNA; Tyrosine

Topics: Alzheimer Disease; Biomarkers; DNA Damage; Glycation End Products, Advanced; Histocytochemistry; Humans; Immunohistochemistry; Metals; Oxidation-Reduction; Oxidative Stress; Phenylhydrazines; Tyrosine

Topics: Age of Onset; Aged; Aged, 80 and over; Alzheimer Disease; Amino Acid Substitution; Female; Histidine; Humans; Male; Membrane Proteins; Middle Aged; Pedigree; Penetrance; Point Mutation; Presenilin-1; Tyrosine

Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Autophagy; Disease Models, Animal; Hippocampus; Mice, Inbred C57BL; Mice, Transgenic; Neuroprotective Agents; Presenilin-1; Psychomotor Performance; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Receptors, Cannabinoid; Spatial Memory; Tyrosine

Topics: Alzheimer Disease; Animals; Disks Large Homolog 4 Protein; Hippocampus; Male; Phosphorylation; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Transcription Factors; Tyrosine

Topics: Alzheimer Disease; Animals; Humans; Mice; Microtubules; Peptides; Tubulin; Tyrosine

Topics: Alzheimer Disease; Animals; Dipeptides; Disease Models, Animal; Mice; Mice, Transgenic; tau Proteins; Tauopathies; Tryptophan; Tyrosine

Topics: Alzheimer Disease; Humans; Phosphoprotein Phosphatases; Phosphorylation; Protein Phosphatase 2; Proto-Oncogene Proteins c-fyn; Proto-Oncogene Proteins pp60(c-src); src-Family Kinases; tau Proteins; Tyrosine

Topics: alpha-Synuclein; Alzheimer Disease; Humans; Neurofibrillary Tangles; Protein Conformation, alpha-Helical; tau Proteins; Tyrosine

Topics: Alzheimer Disease; Amyloid; Amyloid beta-Peptides; Flavonoids; Humans; Peptide Fragments; Quercetin; Tyrosine

Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Disease Models, Animal; Down Syndrome; Drosophila; Dyrk Kinases; Humans; Neurotoxicity Syndromes; Phosphorylation; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; tau Proteins; Tyrosine

Topics: Alzheimer Disease; Amyloid; Amyloid beta-Peptides; Animals; Disease Models, Animal; Frontotemporal Dementia; Humans; Mice; Mice, Transgenic; Protein Tyrosine Phosphatases; Protein Tyrosine Phosphatases, Non-Receptor; tau Proteins; Tyrosine

Topics: Alzheimer Disease; Humans; Immunotherapy; Microglia; Signal Transduction; Syk Kinase; Tyrosine

Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Aspartic Acid Endopeptidases; Humans; Metal Nanoparticles; Metal-Organic Frameworks; Silver; Tyrosine

Topics: Alzheimer Disease; Humans; Molecular Docking Simulation; Neoplasms; Phytochemicals; Proto-Oncogene Proteins c-fyn; Tyrosine

Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Cognition; Donepezil; Humans; Metabolome; Methionine; Mice; Mice, Inbred ICR; Neuroblastoma; Phenylalanine; Reactive Oxygen Species; Scopolamine Derivatives; Tyrosine

Topics: Acetone; Aged; Alzheimer Disease; Biomarkers; Cognitive Dysfunction; Glutamates; Histidine; Humans; Isobutyrates; Isoleucine; Leucine; Magnetic Resonance Spectroscopy; Tyrosine; Valine

Topics: Alzheimer Disease; Amyloid beta-Peptides; Copper; Humans; Ions; Spectrometry, Fluorescence; Tyrosine

Topics: Alzheimer Disease; Animals; Basal Ganglia; Brain; Carbohydrates; Catalysis; Colon; Densitometry; Diabetes Mellitus, Type 2; Dietary Carbohydrates; Gastrointestinal Microbiome; Gene Expression Regulation, Enzymologic; Humans; Hydroxylation; Immunohistochemistry; Levodopa; Male; Phoeniceae; Phytochemicals; Rats; Tyrosine; Tyrosine 3-Monooxygenase

Topics: Aged; Aged, 80 and over; Alzheimer Disease; Erythrocytes; Humans; Phosphorylation; Signal Transduction; Tyrosine

Topics: Adult; Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Protein Precursor; Biomarkers; Cells, Cultured; Female; Humans; Induced Pluripotent Stem Cells; Male; Middle Aged; Neural Stem Cells; Neurons; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-fyn; Transfection; Tyrosine

Topics: Alzheimer Disease; Amyloid beta-Peptides; Fluorescence; Humans; Islet Amyloid Polypeptide; Microscopy, Electron, Scanning; Protein Aggregates; Protein Aggregation, Pathological; Protein Structure, Secondary; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Static Electricity; Tyrosine

Topics: Administration, Oral; Alzheimer Disease; Animals; Behavior, Animal; Calcium Channel Agonists; Calcium Channels, T-Type; Cognition; Disease Models, Animal; Drug Administration Schedule; Hippocampus; Imidazoles; Male; Mice; Microglia; Molecular Structure; Olfactory Bulb; Oxidative Stress; Spatial Memory; Spiro Compounds; Tyrosine

Topics: alpha-MSH; Alzheimer Disease; Amyloid beta-Peptides; Animals; Astrocytes; Hippocampus; Humans; Mice; Mice, Inbred C57BL; Neuroprotective Agents; Peptides, Cyclic; Receptors, Melanocortin; Tyrosine

Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Imidazoles; Janus Kinase 2; Janus Kinases; Male; Mice; Rats; Receptor for Advanced Glycation End Products; Signal Transduction; STAT Transcription Factors; Tyrosine

Topics: Aged; Aged, 80 and over; Alzheimer Disease; Biomarkers; Cognition; Cognitive Dysfunction; Cohort Studies; Female; Humans; Lewy Body Disease; Male; Tyrosine

Topics: Alzheimer Disease; Animals; Biomarkers; Brain; Disease Models, Animal; Drugs, Chinese Herbal; Gastrointestinal Microbiome; Inflammation; Mass Spectrometry; Medicine, Chinese Traditional; Metabolomics; Nervous System; Panax; Phenylalanine; Plant Extracts; Rats; Reproducibility of Results; Schisandra; Tandem Mass Spectrometry; Tyrosine; Urinalysis

Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Glycopeptides; Humans; Tyrosine

Topics: Alzheimer Disease; Amyloid beta-Peptides; Brain; Brain Chemistry; Humans; Mass Spectrometry; Protein Multimerization; Tyrosine

Topics: Activating Transcription Factor 6; Alzheimer Disease; Animals; Brain; Cyclic AMP Response Element-Binding Protein; Disease Models, Animal; eIF-2 Kinase; Endoplasmic Reticulum Stress; Glycogen Synthase Kinase 3; Male; Membrane Proteins; Phosphorylation; Protein Serine-Threonine Kinases; Rats, Sprague-Dawley; Serine; Spatial Memory; Tunicamycin; Tyrosine; Unfolded Protein Response

Topics: Alzheimer Disease; Amyloid beta-Peptides; Cacao; Catechols; Cinnamates; Dihydroxyphenylalanine; Humans; Inhibitory Concentration 50; Structure-Activity Relationship; Tyrosine

Topics: Aged; Aged, 80 and over; Alzheimer Disease; Brain; Disease Progression; Female; Humans; Male; Middle Aged; Phosphorylation; Psychiatric Status Rating Scales; Serine; Statistics, Nonparametric; tau Proteins; Threonine; Tyrosine

Topics: Alzheimer Disease; Chromatography, Liquid; Copper; Electrochemical Techniques; Humans; Neuropeptide Y; Nitrates; Nitrosative Stress; Oxidative Stress; Protein Binding; Spectrometry, Fluorescence; Spectrometry, Mass, Electrospray Ionization; Spectrophotometry, Ultraviolet; Tyrosine

Topics: Aldehydes; Alzheimer Disease; Amyloid beta-Protein Precursor; Amyloidosis; Animals; CA1 Region, Hippocampal; Cytokines; Disease Models, Animal; Encephalitis; Humans; Lithium; Mice, Transgenic; Mutation; Plaque, Amyloid; Rats; Tyrosine

Topics: Aged; Aged, 80 and over; Alzheimer Disease; Antioxidants; Biomarkers; Case-Control Studies; CD3 Complex; Cell Separation; Cytoskeletal Proteins; Energy Metabolism; Female; Gene Expression; Humans; Lymphocytes; Male; Middle Aged; Nitro Compounds; Nitrosative Stress; Oxidative Stress; Primary Cell Culture; Proteome; Signal Transduction; Tyrosine

Topics: Alzheimer Disease; Amyloid; Amyloid beta-Peptides; Benzothiazoles; Copper; Humans; Hydrogen Peroxide; Microscopy, Electron, Transmission; Oxidation-Reduction; Oxidative Stress; Peptide Fragments; Plaque, Amyloid; Protein Multimerization; Tyrosine

Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Antibodies; Basic Helix-Loop-Helix Transcription Factors; Disease Models, Animal; Female; Hippocampus; Humans; Induced Pluripotent Stem Cells; Long-Term Potentiation; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Nerve Tissue Proteins; Neural Inhibition; Peptide Fragments; Synapses; Tyrosine

Topics: Alzheimer Disease; Apoptosis Regulatory Proteins; Biophysical Phenomena; Caspase 3; Cell Nucleus; Circular Dichroism; Dynamic Light Scattering; Fluorescence; Genes, Tumor Suppressor; Humans; Hydrogen-Ion Concentration; NF-kappa B; Protein Aggregation, Pathological; Protein Domains; Protein Folding; Proto-Oncogene Proteins c-bcl-2; Tyrosine

Topics: Aged; Alzheimer Disease; Amyloid beta-Peptides; Case-Control Studies; Chromatography, Liquid; Female; Glycopeptides; Humans; Male; Middle Aged; Molecular Structure; Tandem Mass Spectrometry; Tyrosine

Topics: Age Factors; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Brain; Diet, Ketogenic; Disease Models, Animal; Humans; Mice; Mice, Transgenic; Movement Disorders; Muscle, Skeletal; Presenilin-1; Reaction Time; Tyrosine

Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Brain; Down-Regulation; Humans; Mice; Mice, Transgenic; Neurons; Phosphoprotein Phosphatases; Phosphorylation; Protein Phosphatase 2; Protein Tyrosine Phosphatase, Non-Receptor Type 1; tau Proteins; Tyrosine; Up-Regulation

Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cognition Disorders; Enzyme-Linked Immunosorbent Assay; Female; Humans; Kynurenine; Male; Middle Aged; Neopterin; Neuropsychological Tests; Phenylalanine; Psychiatric Status Rating Scales; Single-Blind Method; Statistics, Nonparametric; Tyrosine

Topics: Alzheimer Disease; Amyloid beta-Peptides; Dimerization; Hemin; Humans; Kinetics; Nitrates; Oxidation-Reduction; Peptide Fragments; Tyrosine

Topics: Alzheimer Disease; Catechols; Cognition Disorders; Humans; Metabolic Networks and Pathways; Methionine; Models, Biological; Molecular Structure; Oxidative Stress; Parkinson Disease; Phenylalanine; Phenylketonurias; Tyrosine

Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Biomarkers; Cells, Cultured; Copper; Female; Humans; Male; Neuroblastoma; Oxidative Stress; Peptide Fragments; Plaque, Amyloid; Tyrosine

Topics: Alzheimer Disease; Animals; Autophagy; Cell Line; Cell Line, Tumor; Dioxoles; Dyrk Kinases; Enzyme Inhibitors; Humans; Imidazoles; Mice; Microtubule-Associated Proteins; Osteosarcoma; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; TOR Serine-Threonine Kinases; Tyrosine

Topics: Aged; Albumins; Alzheimer Disease; Amyloid beta-Peptides; Brain; Cells, Cultured; Dose-Response Relationship, Drug; Endothelial Cells; Female; Glycosylation; Humans; Male; Molsidomine; Neurons; Peptide Fragments; Protein Aggregates; Protein Processing, Post-Translational; tau Proteins; Trypsin; Tyrosine

Topics: Adult; Alzheimer Disease; Amino Acid Substitution; Asian People; Asparagine; Codon; Female; Genes, Dominant; Genetic Association Studies; Humans; Male; Middle Aged; Mutation, Missense; Pedigree; Phenotype; Presenilin-2; Tyrosine

Topics: Alzheimer Disease; Amyloid beta-Peptides; Electrochemical Techniques; Electrodes; Graphite; Humans; Microscopy, Atomic Force; Oxidation-Reduction; Peptide Fragments; Tyrosine

Topics: Abdomen; Acetylcholine; Adipose Tissue; Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Arterioles; Endothelial Cells; Female; Humans; Male; Meninges; Middle Aged; Oxidative Stress; Papaverine; Peptide Fragments; Reactive Oxygen Species; Tyrosine; Vasodilator Agents

Topics: Alzheimer Disease; Amino Acid Sequence; Amyloid beta-Peptides; Animals; Arginine; Heme; Histidine; Humans; Mice; Molecular Sequence Data; Mutation; Oxidation-Reduction; Peptide Fragments; Peroxidases; Solutions; Tyrosine

Topics: Alzheimer Disease; Epigenesis, Genetic; Gene Expression Regulation; HeLa Cells; Histone Deacetylase 2; Humans; Neurons; Phosphorylation; Proto-Oncogene Proteins c-abl; Tyrosine

Topics: Activities of Daily Living; Aged; Aged, 80 and over; Alzheimer Disease; Case-Control Studies; Female; Gene Expression; Humans; Lipoproteins, LDL; Male; Middle Aged; Neuropsychological Tests; Severity of Illness Index; Tyrosine

Topics: Aged; Alzheimer Disease; Feces; Female; Humans; Leukocyte L1 Antigen Complex; Male; Phenylalanine; Tryptophan; Tyrosine

Topics: Alzheimer Disease; Amyloid beta-Peptides; Copper; Humans; Peptide Fragments; Peroxidase; Protein Aggregation, Pathological; Tyrosine

Topics: Alzheimer Disease; Amyloid beta-Peptides; Humans; Serum Albumin; Spectrometry, Fluorescence; Tyrosine

Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Ascorbic Acid; Calcium Signaling; Cell Membrane Permeability; Cells, Cultured; Copper; Humans; Lipid Peroxidation; Mice, Inbred C57BL; Neurons; Peptide Fragments; Protein Aggregates; Pyrrolidonecarboxylic Acid; Reactive Oxygen Species; Tyrosine

Topics: Acetylcholinesterase; Alzheimer Disease; Amyloid Precursor Protein Secretases; Aspartic Acid Endopeptidases; Binding Sites; Butyrylcholinesterase; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Ginsenosides; Molecular Docking Simulation; Oxidative Stress; Peroxynitrous Acid; Protease Inhibitors; Protein Binding; Protein Conformation; Structure-Activity Relationship; Tyrosine

Topics: Aging; Alzheimer Disease; Animals; Disease Models, Animal; Energy Metabolism; Glutamic Acid; Hippocampus; Mice, Transgenic; Microelectrodes; Mitochondria; Neurotransmitter Agents; Nitric Oxide; Oxidative Phosphorylation; Oxygen Consumption; Peroxynitrous Acid; Receptors, N-Methyl-D-Aspartate; Synaptic Transmission; Tyrosine

Topics: Alzheimer Disease; Amyloid beta-Peptides; Base Sequence; Case-Control Studies; Cell Line, Tumor; Frontal Lobe; Genes, Reporter; Humans; Luciferases; MicroRNAs; Models, Biological; Neurons; Oligoribonucleotides, Antisense; Peptide Fragments; Phosphorylation; Protein Processing, Post-Translational; Proto-Oncogene Proteins c-fyn; RNA, Small Interfering; Signal Transduction; tau Proteins; Temporal Lobe; Tyrosine

Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Brain; Cell Line; Chromosomes, Human, Pair 21; Down Syndrome; Down-Regulation; Dyrk Kinases; Enzyme Inhibitors; Fibroblasts; Harmine; Humans; Neprilysin; Phosphorylation; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Tyrosine

Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Blood Proteins; Cerebrospinal Fluid Proteins; Female; Humans; Male; Middle Aged; Nitroso Compounds; Oxidation-Reduction; Oxidative Stress; Protein Carbonylation; Reference Values; Tyrosine

Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amino Acid Sequence; Antibodies, Monoclonal; Antibody Specificity; Astrocytes; Brain; Female; Glial Fibrillary Acidic Protein; Gliosis; Humans; Immunohistochemistry; Male; Neurofibrillary Tangles; Nitrates; Plaque, Amyloid; Protein Processing, Post-Translational; tau Proteins; Tyrosine

Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Blotting, Western; Case-Control Studies; Cell Line; Cell Line, Tumor; Frontal Lobe; Humans; Immunohistochemistry; Mice; Mice, Transgenic; Microscopy, Atomic Force; Microscopy, Confocal; Microscopy, Electron; Models, Molecular; Neuroblastoma; Neurofibrillary Tangles; Oxidative Stress; Peroxynitrous Acid; Phosphorylation; tau Proteins; Triose-Phosphate Isomerase; Tyrosine

Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid; Analysis of Variance; Case-Control Studies; Female; Hippocampus; Humans; Immunoprecipitation; Male; Microscopy, Confocal; Middle Aged; Neurofilament Proteins; Phosphorylation; Proto-Oncogene Proteins c-abl; Subcellular Fractions; tau Proteins; Threonine; Tyrosine

Topics: Alzheimer Disease; Amino Acid Sequence; Amyloid beta-Peptides; Cholesterol; Ergosterol; Fluorescence Polarization; Fluorescence Resonance Energy Transfer; Lipid Bilayers; Molecular Sequence Data; Peptide Fragments; Protein Binding; Time Factors; Tyrosine

Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Female; Humans; Magnetic Resonance Imaging; Middle Aged; Mutation; Peptide Fragments; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Threonine; Tyrosine

Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Brain; CD40 Antigens; Disease Models, Animal; Female; Humans; Immunoprecipitation; Male; Matrix Metalloproteinase 9; Maze Learning; Mice; Mice, Transgenic; Minocycline; Nerve Growth Factor; Nerve Growth Factors; Nitric Oxide Synthase Type II; Peptide Fragments; Peroxynitrous Acid; Protein Precursors; Rats; Rats, Inbred F344; Reaction Time; Tyrosine; Up-Regulation

Topics: Alzheimer Disease; Amyloid beta-Peptides; Binding Sites; Biophysics; Chemistry, Physical; Histidine; Humans; Ligands; Magnetic Resonance Spectroscopy; Molecular Conformation; Monte Carlo Method; Peptides; Protein Binding; Tyrosine; Zinc

Topics: Alzheimer Disease; Humans; Microtubules; Molecular Sequence Data; Mutagenesis, Site-Directed; Neurofibrillary Tangles; Protein Binding; Protein Multimerization; Protein Structure, Tertiary; Repetitive Sequences, Amino Acid; tau Proteins; Tyrosine

Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Astrocytes; Brain; Bridged Bicyclo Compounds; Disease Models, Animal; Encephalitis; Glial Fibrillary Acidic Protein; Gliosis; Humans; Maze Learning; Memory Disorders; Mice; Mice, Transgenic; Oxidative Stress; Phloroglucinol; Terpenes; Tyrosine

Topics: Aged; Aged, 80 and over; Aldehydes; Alzheimer Disease; Antioxidants; Biomarkers; Disease Progression; Female; Frontal Lobe; Humans; Male; Mental Status Schedule; Oxidative Stress; Protein Carbonylation; Synapses; Thiobarbituric Acid Reactive Substances; Tissue Distribution; Tyrosine

Topics: Adenosine Triphosphate; Alzheimer Disease; Analysis of Variance; Brain; Cell Line, Tumor; Humans; Immunoprecipitation; Microtubules; Neuroblastoma; Neurofibrillary Tangles; Phosphorylation; Protein Binding; Protein-Tyrosine Kinases; Proto-Oncogene Proteins c-abl; tau Proteins; Time Factors; Transfection; Tyrosine

Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Case-Control Studies; Electrophoresis, Gel, Two-Dimensional; Enzyme-Linked Immunosorbent Assay; Female; Humans; Lipid Peroxidation; Male; Oxidative Stress; Parietal Lobe; Peptide Fragments; Protein Carbonylation; Proteomics; Spectrum Analysis; Tyrosine

Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; CA1 Region, Hippocampal; Disease Models, Animal; Disks Large Homolog 4 Protein; Enzyme Activation; Feedback, Physiological; Intracellular Signaling Peptides and Proteins; Male; Membrane Proteins; Neurons; Peptide Fragments; Phosphorylation; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; src-Family Kinases; Synaptic Transmission; Tyrosine; Up-Regulation

Topics: Alzheimer Disease; Cholinesterase Inhibitors; Chromatography, Liquid; Gels; Humans; Neuroprotective Agents; Phenylcarbamates; Rivastigmine; Tandem Mass Spectrometry; Tyrosine

Topics: Age Factors; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Brain; Caspase 3; Cell Death; Disease Models, Animal; Humans; Luciferases; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Nerve Growth Factor; Neurons; Nitric Oxide Synthase Type II; PC12 Cells; Peptide Fragments; Phosphorylation; Presenilin-1; Rats; Receptors, TNF-Related Apoptosis-Inducing Ligand; RNA, Small Interfering; Signal Transduction; STAT3 Transcription Factor; Time Factors; Transfection; TYK2 Kinase; Tyrosine

Topics: Acetylcysteine; Aged; Alzheimer Disease; Amyloid beta-Peptides; Cell Survival; Cells, Cultured; DNA, Mitochondrial; Female; Glutathione; Humans; Hybrid Cells; Male; Mitochondria; Mitogen-Activated Protein Kinases; Nerve Growth Factors; Neurons; NF-kappa B; Peptide Fragments; Phosphorylation; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Receptor, trkA; Receptors, Nerve Growth Factor; Signal Transduction; Tyrosine

Topics: Alzheimer Disease; Animals; Disease Models, Animal; Disease Progression; Fluorescent Antibody Technique; Humans; Mice; Mice, Transgenic; Microscopy, Confocal; Microscopy, Immunoelectron; Phosphorylation; Proliferating Cell Nuclear Antigen; Proto-Oncogene Proteins c-fyn; src-Family Kinases; tau Proteins; Tauopathies; Tyrosine

Topics: Alzheimer Disease; Amyloid beta-Peptides; Anisotropy; Buffers; Catalysis; Dimerization; Dose-Response Relationship, Drug; Humans; Kinetics; Peptide Fragments; Peptides; Protein Structure, Tertiary; Proteins; Rhodamines; Thermodynamics; Tyrosine

Topics: Aged; Alzheimer Disease; Amyloid beta-Peptides; Arginine; Female; Humans; Male; Malondialdehyde; Middle Aged; Nitric Oxide; Nitric Oxide Synthase Type II; Oxidative Stress; Peptide Fragments; Peroxynitrous Acid; Reactive Oxygen Species; Tyrosine

Topics: Adult; Aged; Alzheimer Disease; Codon, Nonsense; Depressive Disorder, Major; Female; Glutamine; Humans; Memory Disorders; Memory, Short-Term; Middle Aged; Neurofibrillary Tangles; Neuropsychological Tests; Phenotype; Prion Diseases; Prion Proteins; Prions; tau Proteins; Tyrosine

Topics: Alzheimer Disease; Brain; Cell Line; Citric Acid Cycle; Enzyme Activation; Humans; Ketoglutarate Dehydrogenase Complex; Mitochondria; Mitochondrial Proteins; Peroxynitrous Acid; Tyrosine

Topics: Aged; Aged, 80 and over; Aldehydes; Alzheimer Disease; Blotting, Western; Brain; Cerebellum; Cognitive Dysfunction; Female; Heme Oxygenase (Decyclizing); Hippocampus; Homeostasis; Humans; Immunoprecipitation; Male; Nitric Oxide Synthase Type II; Oxidative Stress; Oxidoreductases Acting on CH-CH Group Donors; Protein Carbonylation; Reactive Nitrogen Species; Tyrosine

Topics: Aged; Aged, 80 and over; Alzheimer Disease; Blotting, Western; Enzyme-Linked Immunosorbent Assay; Female; Fluorescent Antibody Technique; Humans; Immunohistochemistry; Inclusion Bodies; Male; Middle Aged; Nitrosation; Proline; tau Proteins; Tyrosine

Topics: Alzheimer Disease; Amino Acid Sequence; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Chromatography, Liquid; Glycosylation; Humans; Molecular Sequence Data; Proteomics; Serine; Tandem Mass Spectrometry; Threonine; Tyrosine

Topics: Alzheimer Disease; Analysis of Variance; Animals; Axonal Transport; Brain; Decapodiformes; Enzyme-Linked Immunosorbent Assay; Humans; Mutation; Neural Inhibition; Phosphorylation; Protein Interaction Domains and Motifs; Protein Isoforms; Proto-Oncogene Proteins c-fyn; Signal Transduction; tau Proteins; Time Factors; Tyrosine

Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Cells, Cultured; Female; Hippocampus; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Nerve Growth Factor; Phosphorylation; Receptor, trkA; Signal Transduction; Tyrosine

Topics: Age Factors; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloidosis; Animals; Biophysics; Brain; Disease Models, Animal; Drug Combinations; Electric Stimulation; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation; Hippocampus; Humans; Immunoprecipitation; In Vitro Techniques; Long-Term Potentiation; Maze Learning; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Neurons; Nitric Oxide Synthase Type II; Patch-Clamp Techniques; Peptide Fragments; Peroxynitrous Acid; Plaque, Amyloid; Presenilin-1; Tyrosine

Topics: Adolescent; Adult; Age Factors; Aldehydes; Alzheimer Disease; Amyloid beta-Peptides; Biomarkers; Down Syndrome; Female; Frontal Lobe; Humans; Male; Middle Aged; Nitrosation; Oxidation-Reduction; Oxidative Stress; Superoxide Dismutase; Superoxide Dismutase-1; Tyrosine

Topics: Age Factors; Alzheimer Disease; Amyloid beta-Peptides; Analysis of Variance; Animals; Animals, Newborn; Antioxidants; Caspases; Cell Death; Cells, Cultured; Cerebral Cortex; Disease Models, Animal; Enzyme Inhibitors; Enzyme-Linked Immunosorbent Assay; Glial Fibrillary Acidic Protein; Gliosis; Glutathione; Humans; Lipid Peroxidation; Maze Learning; Memory Disorders; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mitochondria; Neurons; Organophosphorus Compounds; Oxidative Stress; Peptide Fragments; Retention, Psychology; Rhodamines; Space Perception; Time Factors; Tyrosine; Ubiquinone

Topics: Adult; Aged; Aged, 80 and over; Alzheimer Disease; Antibodies, Monoclonal; Female; Humans; Immunohistochemistry; Male; Middle Aged; Neurons; Nitrates; Phosphorylation; Pick Disease of the Brain; Supranuclear Palsy, Progressive; tau Proteins; Tauopathies; Tyrosine

Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Cell Line, Tumor; Circular Dichroism; Dendrimers; Humans; Mice; Microscopy, Electron, Transmission; Phosphorus; tau Proteins; Tyrosine

Topics: Adaptor Proteins, Signal Transducing; Alzheimer Disease; Amyloid beta-Protein Precursor; Biochemistry; Biophysics; Crystallography, X-Ray; DNA Mutational Analysis; HEK293 Cells; Humans; Kinetics; Magnetic Resonance Spectroscopy; Molecular Conformation; Nerve Tissue Proteins; Neurons; Protein Binding; Protein Structure, Tertiary; Tyrosine

Topics: Alzheimer Disease; Amino Acid Sequence; Amino Acid Substitution; Amyloid beta-Peptides; Humans; Oxidative Stress; Peptide Fragments; Tyrosine

Topics: Alzheimer Disease; Amyloid; Anisotropy; Conserved Sequence; Detergents; Fluorescent Dyes; Humans; Kinetics; Models, Molecular; Molecular Conformation; Neurons; Peptides; Protein Conformation; Protein Structure, Tertiary; Spectrometry, Fluorescence; Tyrosine

Topics: Alzheimer Disease; Amino Acid Substitution; Amyloid beta-Peptides; Animals; Cells, Cultured; Humans; Hydrogen Peroxide; Neurons; Peptide Fragments; Phenylalanine; Protein Aggregation, Pathological; Protein Folding; Protein Structure, Secondary; Rats, Sprague-Dawley; Tyrosine

Topics: Acetylcholinesterase; Alzheimer Disease; Animals; Avoidance Learning; Benzene Derivatives; Brain; Dietary Supplements; Disease Models, Animal; Energy Metabolism; Male; Maze Learning; Neuroprotective Agents; Organoselenium Compounds; Oxidative Stress; Rats; Rats, Wistar; Streptozocin; Tyrosine

Topics: Alzheimer Disease; Amino Acid Sequence; Amyloid beta-Peptides; Animals; Fluorescent Dyes; Humans; Mice; Molecular Sequence Data; Protein Binding; Tyrosine

Topics: Alzheimer Disease; Amino Acid Motifs; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Aspartic Acid Endopeptidases; Blotting, Western; Brain; Cell Differentiation; Cell Line; Cell Nucleus; Cells, Cultured; Cytoplasm; Endopeptidases; Glutathione Transferase; Humans; Immunohistochemistry; Luciferases; Membrane Proteins; Mice; Mice, Knockout; Microscopy, Fluorescence; Nerve Tissue Proteins; Point Mutation; Precipitin Tests; Protein Binding; Protein Structure, Tertiary; Receptors, Notch; Transcription, Genetic; Transcriptional Activation; Tyrosine

Topics: Aged; Aged, 80 and over; Alzheimer Disease; Biomarkers; Brain; Female; Humans; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxidative Stress; Peroxynitrous Acid; Pyramidal Cells; Tyrosine

Topics: Adult; Aged; Aged, 80 and over; Alzheimer Disease; Amino Acids; Analysis of Variance; Body Composition; Body Mass Index; Case-Control Studies; Chi-Square Distribution; Creatinine; Disabled Persons; Female; Humans; Insulin-Like Growth Factor I; Male; Middle Aged; Phenylalanine; Tyrosine

Topics: Aged; Aged, 80 and over; Alzheimer Disease; Blotting, Western; Brain Chemistry; Electrophoresis, Gel, Two-Dimensional; Female; Humans; Male; Nerve Tissue Proteins; Nitrates; Oxidative Stress; Peroxynitrous Acid; Phosphopyruvate Hydratase; Proteins; Proteomics; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Triose-Phosphate Isomerase; Tyrosine

Topics: Adult; Alzheimer Disease; Amino Acid Substitution; Amyloid beta-Peptides; Blotting, Western; Brain; DNA Mutational Analysis; Enzyme-Linked Immunosorbent Assay; Family Health; Female; Glutamine; Histidine; Humans; Immunohistochemistry; Membrane Proteins; Mutation, Missense; Pedigree; Peptide Fragments; Plaque, Amyloid; Presenilin-1; Serine; Tyrosine

Topics: Aged; Aged, 80 and over; Alzheimer Disease; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Case-Control Studies; Female; Humans; Immunohistochemistry; Male; Mental Status Schedule; Olfaction Disorders; Olfactory Receptor Neurons; Sensory Thresholds; Thiolester Hydrolases; Tyrosine; Ubiquitin Thiolesterase

Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Chemical Precipitation; Humans; Mathematics; Peptide Fragments; Solubility; Spectrometry, Fluorescence; Thermodynamics; Tyrosine

Topics: Age of Onset; Aged; Aged, 80 and over; Alzheimer Disease; Amyloid Precursor Protein Secretases; Apolipoprotein E4; Apolipoproteins E; Asparagine; Case-Control Studies; Female; Genotype; Humans; Male; Membrane Glycoproteins; Mutation, Missense; Polymorphism, Single-Stranded Conformational; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tyrosine

Topics: Alzheimer Disease; Amino Acid Sequence; Amyloid beta-Peptides; Animals; Copper; Cross-Linking Reagents; Humans; Molecular Sequence Data; Oxidation-Reduction; Peptide Fragments; Rats; Sodium Dodecyl Sulfate; Spectrometry, Fluorescence; Spectrometry, Mass, Electrospray Ionization; Tyrosine

Topics: Age Factors; Alzheimer Disease; Animals; Antibodies, Monoclonal; Antibody Affinity; Antibody Specificity; Brain; Cell Line; Chlorocebus aethiops; Humans; Immunohistochemistry; Mice; Microtubules; Nerve Degeneration; Phosphorylation; Protein Tyrosine Phosphatases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-fyn; tau Proteins; Tyrosine

Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cell Death; Humans; Immunohistochemistry; Middle Aged; Nerve Degeneration; Nerve Tissue Proteins; Neurons; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Pyramidal Cells; Temporal Lobe; Tyrosine

Topics: Adult; Aged; Aged, 80 and over; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Biomarkers; Female; Humans; Male; Middle Aged; Tyrosine

Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Cerebrovascular Circulation; Free Radical Scavengers; Free Radicals; Humans; Hyperemia; Mice; Oxidative Stress; Peptide Fragments; Physical Stimulation; Reactive Oxygen Species; Regional Blood Flow; Somatosensory Cortex; Tyrosine

Topics: Alzheimer Disease; Animals; Anisomycin; Anthracenes; Brain; Cell Line; Cell Line, Tumor; COS Cells; Down-Regulation; Enzyme Inhibitors; Estradiol; Flavonoids; Genetic Vectors; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hippocampus; Humans; Immunohistochemistry; In Vitro Techniques; Mice; Microscopy, Fluorescence; Mitogen-Activated Protein Kinases; Neurons; Oxidoreductases; Phosphorylation; Precipitin Tests; Protein Binding; Protein Structure, Tertiary; Retroviridae; RNA, Small Interfering; Serine; tau Proteins; Temperature; Threonine; Time Factors; Tumor Suppressor Proteins; Two-Hybrid System Techniques; Tyrosine; WW Domain-Containing Oxidoreductase

Topics: Aged; Aged, 80 and over; Alzheimer Disease; Analysis of Variance; Apolipoproteins E; Case-Control Studies; Chi-Square Distribution; Cholesterol 24-Hydroxylase; Cysteine; Female; Follow-Up Studies; Gene Frequency; Genetic Predisposition to Disease; Genotype; Humans; Introns; Male; Mental Status Schedule; Odds Ratio; Polymorphism, Genetic; Reverse Transcriptase Polymerase Chain Reaction; Risk Factors; RNA, Messenger; Steroid Hydroxylases; Time Factors; Tyrosine

Topics: Alanine; Alzheimer Disease; Amino Acid Substitution; Amyloid beta-Peptides; Catalysis; Copper; Electron Transport; Hydrogen Peroxide; Mutation; Solubility; Tyrosine

Topics: Aging; Aldehydes; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Biomarkers; Brain; Cells, Cultured; Disease Models, Animal; Down-Regulation; Glutamate-Ammonia Ligase; Lipid Peroxidation; Memory Disorders; Mice; Mice, Inbred Strains; Neurons; Oligonucleotides, Antisense; Oxidative Stress; Rats; Rats, Sprague-Dawley; Thiobarbituric Acid Reactive Substances; Tyrosine

Topics: Alzheimer Disease; Asparagine; Female; Humans; Male; Membrane Proteins; Middle Aged; Mutation; Paraparesis, Spastic; Pedigree; Presenilin-1; Tyrosine

Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Astrocytes; Blotting, Western; Cerebral Cortex; Disease Models, Animal; Female; Glial Fibrillary Acidic Protein; Immunohistochemistry; Mice; Mice, Transgenic; Microscopy, Confocal; Neurons; Nitric Oxide; Nitric Oxide Synthase; Plaque, Amyloid; Tyrosine

Topics: Aged; Alzheimer Disease; Biomarkers; Cerebrospinal Fluid Proteins; Cognition Disorders; Female; Glycosylation; Humans; Lysine; Male; Neuropsychological Tests; Nitrates; Nitroso Compounds; Oxidation-Reduction; Reference Values; Tyrosine

Topics: Alzheimer Disease; Amino Acid Sequence; Cross-Linking Reagents; Electrophoresis, Polyacrylamide Gel; Light; Molecular Sequence Data; Mutagenesis, Site-Directed; Nitrates; Oxidation-Reduction; Peroxynitrous Acid; Phosphorylation; Protein Processing, Post-Translational; Scattering, Radiation; Sodium Dodecyl Sulfate; tau Proteins; Tyrosine

Topics: Alzheimer Disease; Amino Acid Sequence; Amyloid beta-Peptides; Azides; Chromatography, High Pressure Liquid; Dimerization; Dose-Response Relationship, Radiation; Electrons; Electrophoresis, Polyacrylamide Gel; Free Radicals; Gamma Rays; Humans; Hydrogen Peroxide; Ions; Mass Spectrometry; Methionine; Models, Chemical; Molecular Sequence Data; Oxidation-Reduction; Oxygen; Peptide Fragments; Peptides; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Spectrophotometry; Spectrum Analysis, Raman; Trypsin; Tyrosine

Topics: Acetylcholine; Afferent Pathways; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Axons; Cerebral Cortex; Choline O-Acetyltransferase; Cholinergic Fibers; Denervation; Disease Models, Animal; Female; Hippocampus; Humans; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Oxidative Stress; Presynaptic Terminals; Serotonin; Superoxide Dismutase; Tyrosine; Wallerian Degeneration

Topics: Aged; Alzheimer Disease; Amyloid beta-Peptides; Analysis of Variance; Animals; Antioxidants; Blotting, Western; Brain; Case-Control Studies; Cells, Cultured; Electrophoresis, Gel, Two-Dimensional; Endothelial Cells; Enzyme Activation; Estradiol; Female; Humans; Male; Mice; Neurons; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Proteins; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tyrosine

Topics: Aging; Alzheimer Disease; Animals; Brain; Disease Models, Animal; Female; Humans; Inclusion Bodies; Male; Mice; Mice, Transgenic; Mutation, Missense; Nerve Degeneration; Neurons; Phosphorylation; Protein Isoforms; tau Proteins; Tauopathies; Tyrosine; Up-Regulation

Topics: Alkaloids; Alzheimer Disease; Animals; Binding Sites; Calcium; Calcium Channels; Cholinesterase Inhibitors; Dose-Response Relationship, Drug; Humans; Hydrogen Bonding; Inhibitory Concentration 50; Kinetics; Models, Chemical; Models, Molecular; Molecular Conformation; Neutrophils; Protein Binding; Protein Conformation; Torpedo; Tyrosine

Topics: Alzheimer Disease; Amyloid beta-Peptides; Cadmium; Chromatography, Gel; Circular Dichroism; Humans; Hydrogen-Ion Concentration; Nuclear Magnetic Resonance, Biomolecular; Peptide Fragments; Tyrosine; Zinc

Topics: Alternative Splicing; Alzheimer Disease; Amino Acid Motifs; Animals; Exons; Genes, Dominant; Glutathione Transferase; Humans; Immunohistochemistry; Kinetics; Mice; Mice, Transgenic; Microtubules; Models, Genetic; Mutation; Mutation, Missense; Neurodegenerative Diseases; Phosphorylation; Protein Binding; Protein Structure, Tertiary; Proto-Oncogene Proteins c-fyn; Recombinant Proteins; src Homology Domains; Surface Plasmon Resonance; tau Proteins; Time Factors; Tyrosine

Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Apoptosis; Aspartic Acid; Biological Assay; Brain; Cell Death; Cell Line, Tumor; Cell Survival; Chromosomal Proteins, Non-Histone; Cytoplasm; DNA-Binding Proteins; Down-Regulation; Histone Chaperones; Humans; Immunohistochemistry; Mass Spectrometry; Models, Biological; Neurons; Oligonucleotides, Antisense; Peptides; Protein Binding; Protein Structure, Tertiary; Rats; Recombinant Proteins; Silver Staining; Transcription Factors; Tyrosine

Topics: Alzheimer Disease; Amino Acid Sequence; Amyloid beta-Peptides; Circular Dichroism; Dimethyl Sulfoxide; Disulfides; Humans; Microscopy, Electron; Microscopy, Fluorescence; Molecular Sequence Data; Molecular Weight; Mutation; Peptides; Protein Binding; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Solvents; Spectroscopy, Fourier Transform Infrared; Time Factors; Tyrosine

Topics: Alzheimer Disease; Amino Acid Sequence; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Asparagine; Aspartic Acid Endopeptidases; Binding Sites; Catalysis; Computer Simulation; Crystallography, X-Ray; Endopeptidases; Enzyme Inhibitors; Humans; Hydrogen Bonding; Kinetics; Models, Molecular; Molecular Sequence Data; Oligopeptides; Protein Conformation; Protein Structure, Secondary; Protons; Serine; Substrate Specificity; Temperature; Tyrosine; Water

Topics: Alzheimer Disease; Amyloid beta-Peptides; Cations; Electron Spin Resonance Spectroscopy; Free Radicals; Kinetics; Methionine; Models, Biological; Models, Molecular; Oxidation-Reduction; Oxidative Stress; Peptide Fragments; Peptides; Sulfhydryl Compounds; Tyrosine

Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Brain; Brain Chemistry; Caspase 3; Caspases; Cholinergic Fibers; Disease Models, Animal; Immunohistochemistry; Memory Disorders; Mice; Mice, Transgenic; Pedunculopontine Tegmental Nucleus; REM Sleep Behavior Disorder; Tyrosine

Topics: Aged; Aged, 80 and over; Alzheimer Disease; ATP Synthetase Complexes; Carbonic Anhydrase II; Female; Glyceraldehyde 3-Phosphate Dehydrogenase (NADP+); Hippocampus; Humans; Male; Nerve Degeneration; Nerve Tissue Proteins; Nitrates; Oxidation-Reduction; Oxidative Stress; Phosphopyruvate Hydratase; Phosphorylation; Proteomics; Tyrosine; Voltage-Dependent Anion Channel 1

Topics: Alzheimer Disease; Animals; Embryo, Mammalian; Epithelium; Golgi Apparatus; Melanins; Melanocytes; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Microscopy, Electron, Transmission; Monophenol Monooxygenase; Mutation; Pigmentation; Presenilin-1; Presenilin-2; Protein Transport; Retina; Skin; Tyrosine

Topics: Aldehydes; Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Brain; Bridged-Ring Compounds; Disease Models, Animal; Free Radicals; Gerbillinae; Lipid Peroxidation; Male; Nerve Degeneration; Neurons; Norbornanes; Oxidative Stress; Peptide Fragments; Reactive Oxygen Species; Synaptosomes; Thiocarbamates; Thiones; Type C Phospholipases; Tyrosine

Topics: Alanine; Alzheimer Disease; Animals; Brain; Cattle; Cells, Cultured; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Mutation; Phosphorylation; Serine; tau Proteins; Transfection; Tyrosine

Topics: Adult; Aged; Aged, 80 and over; Alleles; Alzheimer Disease; Case-Control Studies; Chi-Square Distribution; China; DNA Mutational Analysis; Female; Gene Frequency; Genetics, Population; Humans; Male; Middle Aged; Polymorphism, Genetic; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serine; Sex Factors; Tyrosine; Ubiquitin Thiolesterase

Topics: Aging; Alzheimer Disease; Amyloid beta-Peptides; Animals; Brain; Cerebral Cortex; Disease Models, Animal; Homozygote; Mice; Mice, Mutant Strains; Mice, Transgenic; Mitochondria; Oxidative Stress; Respiration; Superoxide Dismutase; Tyrosine

Topics: Aged; Alzheimer Disease; Blood Platelets; Calcium; Diphenylhexatriene; Female; Humans; Male; Middle Aged; Nitric Oxide; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Peroxynitrous Acid; Sodium-Potassium-Exchanging ATPase; Tyrosine

Topics: Alzheimer Disease; Amyloid beta-Peptides; Aspartic Acid; Binding Sites; Copper; Humans; Peptide Fragments; Protein Binding; Spectrum Analysis; Thermodynamics; Tyrosine

Topics: Alzheimer Disease; Animals; Antibodies, Monoclonal; Female; Humans; Mice; Mice, Inbred BALB C; Neurofibrillary Tangles; Nitrates; tau Proteins; Tauopathies; Tyrosine

Topics: Aldehydes; Alzheimer Disease; Animals; Antioxidants; Behavior Therapy; Behavior, Animal; Brain; Disease Models, Animal; Dogs; Electrophoresis, Gel, Two-Dimensional; Gene Expression Regulation; Glutathione Transferase; Heme Oxygenase-1; Proteomics; Superoxide Dismutase; Tyrosine

Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amino Acid Sequence; Biomarkers; Brain; Cytoplasmic Granules; Extracellular Signal-Regulated MAP Kinases; Hippocampus; Humans; Immunohistochemistry; MAP Kinase Kinase 1; MAP Kinase Signaling System; Neurofibrillary Tangles; Phosphorylation; Proto-Oncogene Proteins c-raf; Pyramidal Cells; ras Proteins; Serine; Signal Transduction; Tyrosine; Up-Regulation

Topics: Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Analysis of Variance; Animals; Behavior, Animal; Brain; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Humans; Isoleucine; Magnetic Resonance Imaging; Maze Learning; Mice; Mice, Transgenic; Neurons; Peptide Fragments; Psychomotor Performance; Tyrosine

Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Apoptosis; Brain; Bridged-Ring Compounds; Cytochromes c; Gerbillinae; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Injections, Intraperitoneal; Lipid Peroxidation; Male; Mitochondria; Neurodegenerative Diseases; Neuroprotective Agents; Norbornanes; Oxidation-Reduction; Oxidative Stress; Thiocarbamates; Thiones; Type C Phospholipases; Tyrosine

Topics: Acetylcarnitine; Aldehydes; Alzheimer Disease; Animals; Apoptosis; Cell Survival; Cerebral Cortex; Cyclic GMP-Dependent Protein Kinases; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Lipid Peroxidation; Nerve Degeneration; Neurons; Neuroprotective Agents; Oxidation-Reduction; Oxidative Stress; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Signal Transduction; Thioctic Acid; Tyrosine

Topics: Alzheimer Disease; Amyloid beta-Peptides; Copper; Humans; Solubility; Tyrosine

Topics: Aged, 80 and over; Alzheimer Disease; Amnesia; Biomarkers; Brain; Cognition Disorders; Disease Progression; Early Diagnosis; Female; Hippocampus; Humans; Immunohistochemistry; Male; Nerve Tissue Proteins; Nitrates; Oxidative Stress; Parietal Lobe; Predictive Value of Tests; Prognosis; Tyrosine; Up-Regulation

Topics: Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Cell Line; Down Syndrome; Dyrk Kinases; Gene Expression Regulation; Humans; Mice; Mice, Transgenic; PC12 Cells; Phosphorylation; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Rats; Threonine; Tyrosine

Topics: Aging; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Animals; Antipsychotic Agents; Anxiety; Brain; Dibenzothiazepines; Disease Models, Animal; Female; Male; Memory Disorders; Mice; Mice, Transgenic; Plaque, Amyloid; Presenilin-1; Protease Nexins; Proto-Oncogene Proteins c-bcl-2; Quetiapine Fumarate; Receptors, Cell Surface; Tyrosine

Topics: Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Peptides; Apolipoprotein E4; Case-Control Studies; Cohort Studies; Comorbidity; Complement Factor H; DNA Mutational Analysis; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Histidine; Humans; Macular Degeneration; Male; Middle Aged; Polymorphism, Single Nucleotide; tau Proteins; Tyrosine

Topics: Aldehydes; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Animals, Newborn; Brain; Cell Respiration; Cells, Cultured; Disease Models, Animal; Humans; Membrane Potential, Mitochondrial; Metalloporphyrins; Mice; Mice, Transgenic; Mitochondria; Mitochondrial Diseases; Mutation; Neurons; Oxidative Stress; Presenilin-1; Protein Carbonylation; Superoxide Dismutase; Superoxide Dismutase-1; Tyrosine

Topics: Aged, 80 and over; Alzheimer Disease; Amnesia; Apoptosis; Brain; Cognition Disorders; Female; Humans; Male; Nitrogen; Oxidation-Reduction; Oxidative Stress; Protein Binding; Tumor Suppressor Protein p53; Tyrosine

Topics: Acetylation; Alzheimer Disease; Animals; Biological Transport; Calcium Chloride; Calcium Hydroxide; Cells, Cultured; Cerebral Cortex; Drug Combinations; Dyneins; Enzyme Inhibitors; Microtubules; Neurons; Okadaic Acid; Phosphorylation; Potassium Chloride; Protein Phosphatase 2; Protein Processing, Post-Translational; Rats; Sodium Bicarbonate; Sodium Chloride; Tubulin; Tyrosine

Topics: 3,4-Dihydroxyphenylacetic Acid; Alzheimer Disease; Chromatography, High Pressure Liquid; Depression; Dihydroxyphenylalanine; Electrochemistry; Glycols; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Methoxyhydroxyphenylglycol; Parkinson Disease; Phenylacetates; Subarachnoid Hemorrhage; Tryptophan; Tyrosine

Topics: Alzheimer Disease; Amino Acid Sequence; Calcium-Calmodulin-Dependent Protein Kinases; Glycogen Synthase Kinase 3; Humans; Kinetics; Microtubule-Associated Proteins; Molecular Sequence Data; Peptide Fragments; Phosphopeptides; Phosphorylation; Phosphoserine; Phosphothreonine; Phosphotyrosine; Substrate Specificity; tau Proteins; Tyrosine

Topics: Alzheimer Disease; Amino Acid Sequence; Antibodies, Monoclonal; Genes, Synthetic; Humans; Immunodominant Epitopes; Molecular Sequence Data; Peptide Fragments; Phosphoproteins; Phosphorylation; Phosphoserine; Phosphotyrosine; Protein Conformation; Protein Processing, Post-Translational; Spectroscopy, Fourier Transform Infrared; tau Proteins; Tyrosine

Topics: Aged; Aged, 80 and over; Alzheimer Disease; Antibodies, Monoclonal; Blotting, Western; Chymotrypsin; Epitopes; Humans; Microscopy, Immunoelectron; Neurofibrillary Tangles; Neurofilament Proteins; Peptide Fragments; Peptide Mapping; Phosphotyrosine; tau Proteins; Trypsin; Tyrosine; Ubiquitins

Topics: Aged; Aged, 80 and over; Alzheimer Disease; Blotting, Western; Cell Membrane; Electrophoresis, Polyacrylamide Gel; Female; Hippocampus; Humans; Magnesium; Male; Middle Aged; Molecular Weight; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Proto-Oncogene Proteins pp60(c-src); Tyrosine; Zinc

Topics: Alzheimer Disease; Animals; Blotting, Western; Calcium-Calmodulin-Dependent Protein Kinases; Cattle; Electrophoresis, Polyacrylamide Gel; Female; Fluorescent Antibody Technique; Hippocampus; Humans; Microinjections; Microtubules; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Neurons; Phosphorylation; Phosphotyrosine; Pregnancy; Rats; tau Proteins; Tyrosine

Topics: 3,4-Dihydroxyphenylacetic Acid; Alzheimer Disease; Basal Ganglia; Brain; Brain Chemistry; Caudate Nucleus; Cerebral Cortex; Choline O-Acetyltransferase; Dopamine; Homovanillic Acid; Humans; Lewy Bodies; Parietal Lobe; Putamen; Reference Values; Regression Analysis; Temporal Lobe; Tyrosine; Tyrosine 3-Monooxygenase

Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alzheimer Disease; Antibodies, Monoclonal; Cerebral Cortex; Child, Preschool; Hippocampus; Humans; Immunohistochemistry; Infant, Newborn; Middle Aged; Neurofibrillary Tangles; Neurons; Oxidative Stress; Tyrosine

Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cerebral Cortex; Entorhinal Cortex; Hippocampus; Humans; Immunohistochemistry; Middle Aged; Neurons; Nitrates; Oxidative Stress; Tyrosine

Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cell Nucleus; DNA Damage; DNA Nucleotidylexotransferase; Humans; Middle Aged; Neurofibrillary Tangles; Neurons; Reference Values; Tyrosine; Visual Cortex

Topics: 3-Methoxy-4-hydroxyphenylethanol; Aged; Aged, 80 and over; Alzheimer Disease; Dementia, Vascular; Event-Related Potentials, P300; Humans; Lysine; Middle Aged; Neurotransmitter Agents; Norepinephrine; Tyrosine

Topics: Aged; Aged, 80 and over; Alzheimer Disease; Brain; Brain Chemistry; Chromatography, High Pressure Liquid; Electrochemistry; Female; Free Radical Scavengers; Humans; Male; Nitrates; Nitrites; Oxidation-Reduction; Tyrosine; Uric Acid

Topics: Alzheimer Disease; Amino Acid Substitution; Amyloid beta-Peptides; Animals; Apoptosis; Calcium; Cell Survival; Chromosomes, Human, Pair 14; Humans; Intracellular Membranes; Lipid Peroxidation; Membrane Lipids; Membrane Potentials; Membrane Proteins; Mitochondria; Mutagenesis, Site-Directed; Neurons; PC12 Cells; Peptide Fragments; Presenilin-1; Rats; Reactive Oxygen Species; Recombinant Proteins; Superoxide Dismutase; Superoxides; Tyrosine

Topics: Aldehydes; Alzheimer Disease; Analysis of Variance; Biomarkers; DNA Damage; Glycation End Products, Advanced; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Histocytochemistry; Humans; Iron; Membrane Proteins; Neurodegenerative Diseases; Neurofibrillary Tangles; Neurons; Nitrates; Oxidation-Reduction; Oxidative Stress; Oxygen; Phenylhydrazines; Plaque, Amyloid; Tyrosine

Topics: Adult; Aged; Alzheimer Disease; Antibodies; Biomarkers; Female; Humans; Male; Middle Aged; Nitrates; Nitrogen; Oxidative Stress; Parkinson Disease; Precipitin Tests; Superoxide Dismutase; Tyrosine

Topics: Aged; Aging; Alzheimer Disease; Female; Humans; Male; Middle Aged; Tyrosine

Topics: Alzheimer Disease; Amino Acids; Amyloid beta-Peptides; Arginine; Catalysis; Chromatography, High Pressure Liquid; Copper; Glutamic Acid; Glutamine; Histidine; Humans; Hydrogen Peroxide; Iron; Oxidation-Reduction; Oxygen; Peptide Fragments; Protein Processing, Post-Translational; Time Factors; Tyrosine

Topics: Alzheimer Disease; Amyloid beta-Peptides; Chromatography, High Pressure Liquid; Humans; Hydroxyl Radical; Hydroxylation; Inflammation; Levodopa; Oxidation-Reduction; Oxidative Stress; Peptide Fragments; Tyrosine

Topics: alpha-Synuclein; Alzheimer Disease; Antibodies, Monoclonal; Blotting, Western; Brain; Brain Chemistry; Enzyme-Linked Immunosorbent Assay; Fluorescent Antibody Technique; Humans; Immunohistochemistry; Lewy Bodies; Lewy Body Disease; Microscopy, Immunoelectron; Multiple System Atrophy; Nerve Tissue Proteins; Neurodegenerative Diseases; Neurons; Oxidative Stress; Parkinson Disease; Synucleins; Tyrosine

Topics: Adolescent; Adult; Aged; Alzheimer Disease; Amyloid beta-Protein Precursor; Antibodies; Blotting, Western; Densitometry; Down Syndrome; Female; Humans; Male; Middle Aged; Peptide Fragments; Phosphotyrosine; Pyrrolidonecarboxylic Acid; Tyrosine

Topics: Adaptor Proteins, Signal Transducing; Adaptor Proteins, Vesicular Transport; Alzheimer Disease; Amino Acid Sequence; Amyloid beta-Protein Precursor; Animals; Cell Line; Cell Line, Transformed; Cell Membrane; COS Cells; DNA, Complementary; Glutathione Transferase; Low Density Lipoprotein Receptor-Related Protein-1; Mass Spectrometry; Models, Biological; Molecular Sequence Data; Mutation; Oncogene Protein pp60(v-src); Phosphorylation; Precipitin Tests; Protein Binding; Protein Structure, Tertiary; Proteins; ras Proteins; Receptors, Immunologic; Recombinant Fusion Proteins; Sequence Homology, Amino Acid; Shc Signaling Adaptor Proteins; Signal Transduction; Tyrosine

Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alzheimer Disease; Cerebellum; Child; Child, Preschool; DNA, Mitochondrial; Electron Transport Complex IV; Frontal Lobe; Guanosine; Hippocampus; Humans; Immunohistochemistry; In Situ Hybridization; Microscopy, Electron; Middle Aged; Mitochondria; Neurons; Oxidative Stress; Temporal Lobe; Tyrosine

Topics: Aging; Aldehydes; Alzheimer Disease; Amyloid beta-Peptides; Animals; Benzothiazoles; Brain; Disease Models, Animal; Immunohistochemistry; Mice; Mice, Neurologic Mutants; Mice, Transgenic; Nerve Degeneration; Neurofibrillary Tangles; Oxidative Stress; Thiazoles; Tyrosine

Topics: Aged; Alzheimer Disease; Amyloid beta-Peptides; Apolipoproteins E; Brain; Disease Progression; Female; Genotype; Guanosine; Heterozygote; Humans; Male; Middle Aged; Neurofibrillary Tangles; Neurons; Oxidative Stress; Plaque, Amyloid; Tyrosine

Topics: Aged; alpha-Tocopherol; Alzheimer Disease; Brain; Free Radicals; Glutathione; Humans; Middle Aged; Oxidative Stress; Tyrosine

Topics: Adaptor Proteins, Signal Transducing; Aged; Aged, 80 and over; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Astrocytes; Brain; Enzyme Activation; GRB2 Adaptor Protein; Humans; Immunohistochemistry; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Phosphorylation; Proteins; Rats; Rats, Sprague-Dawley; Signal Transduction; Thrombin; Tyrosine

Topics: Aged; Alzheimer Disease; Amyloid; Animals; Brain Chemistry; Dementia; Female; Histocytochemistry; Humans; Male; Mice; Middle Aged; Organ Specificity; Tryptophan; Tyrosine

Topics: 5-Hydroxytryptophan; Aged; Alzheimer Disease; Carbidopa; Dementia; Dopamine; Drug Combinations; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Neurocognitive Disorders; Probenecid; Serotonin; Tyrosine

Topics: Alzheimer Disease; Animals; Brain; Calcium-Calmodulin-Dependent Protein Kinases; Cattle; Chromatography, Ion Exchange; Cloning, Molecular; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Humans; Molecular Weight; Phosphorylation; Phosphotyrosine; Protein Kinases; Recombinant Proteins; Reference Values; Substrate Specificity; Swine; tau Proteins; Tyrosine

Topics: Aged; Alzheimer Disease; Cerebral Cortex; Energy Metabolism; Free Radicals; Humans; Huntington Disease; Kynurenic Acid; Kynurenine; Middle Aged; Parkinson Disease; Purines; Tryptophan; Tyrosine

Topics: Aged; Alzheimer Disease; Blotting, Western; Humans; Immunohistochemistry; Phosphorylation; Phosphotyrosine; Protein-Tyrosine Kinases; Tyrosine

Topics: Aged; Aged, 80 and over; Alzheimer Disease; Cerebral Cortex; Hippocampus; Humans; Immunohistochemistry; Phosphorylation; Phosphotyrosine; Tyrosine

Topics: Adrenal Gland Neoplasms; Alzheimer Disease; Amyloid; Amyloid beta-Protein Precursor; Animals; Blotting, Western; Carbohydrates; Electrophoresis, Polyacrylamide Gel; Heparin; Immunoassay; Molecular Weight; Peptide Fragments; Pheochromocytoma; Protease Inhibitors; Protein Precursors; Rats; Tumor Cells, Cultured; Tyrosine

Topics: Aged; Alzheimer Disease; Animals; Chromatography, High Pressure Liquid; Electrochemistry; Female; Humans; Male; Middle Aged; Parkinson Disease; Rats; Tryptophan; Tyrosine