tyramine has been researched along with Multiple Sclerosis in 2 studies
Multiple Sclerosis: An autoimmune disorder mainly affecting young adults and characterized by destruction of myelin in the central nervous system. Pathologic findings include multiple sharply demarcated areas of demyelination throughout the white matter of the central nervous system. Clinical manifestations include visual loss, extra-ocular movement disorders, paresthesias, loss of sensation, weakness, dysarthria, spasticity, ataxia, and bladder dysfunction. The usual pattern is one of recurrent attacks followed by partial recovery (see MULTIPLE SCLEROSIS, RELAPSING-REMITTING), but acute fulminating and chronic progressive forms (see MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE) also occur. (Adams et al., Principles of Neurology, 6th ed, p903)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Dissociating glucocorticoid receptor (GR) ligands hold great promise for treating inflammatory disorders since it is assumed that they exert beneficial activities mediated by transrepression but avoid adverse effects of GR action requiring transactivation." | 1.35 | Therapeutic and adverse effects of a non-steroidal glucocorticoid receptor ligand in a mouse model of multiple sclerosis. ( Hanisch, UK; John, M; Lühder, F; Menzfeld, C; Reichardt, HM; Tischner, D; Tuckermann, JP; van den Brandt, J; Wüst, S, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| van Loo, G | 1 |
| Sze, M | 1 |
| Bougarne, N | 1 |
| Praet, J | 1 |
| Mc Guire, C | 1 |
| Ullrich, A | 1 |
| Haegeman, G | 1 |
| Prinz, M | 1 |
| Beyaert, R | 1 |
| De Bosscher, K | 1 |
| Wüst, S | 1 |
| Tischner, D | 1 |
| John, M | 1 |
| Tuckermann, JP | 1 |
| Menzfeld, C | 1 |
| Hanisch, UK | 1 |
| van den Brandt, J | 1 |
| Lühder, F | 1 |
| Reichardt, HM | 1 |
2 other studies available for tyramine and Multiple Sclerosis
| Article | Year |
|---|---|
Antiinflammatory properties of a plant-derived nonsteroidal, dissociated glucocorticoid receptor modulator in experimental autoimmune encephalomyelitis.
Topics: Acetates; Animals; Anti-Inflammatory Agents, Non-Steroidal; Astrocytes; Cells, Cultured; Cytokines; | 2010 |
Therapeutic and adverse effects of a non-steroidal glucocorticoid receptor ligand in a mouse model of multiple sclerosis.
Topics: Acetates; Animals; Apoptosis; Aziridines; Cell Adhesion Molecules; Disease Models, Animal; Dose-Resp | 2009 |