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tyramine and Aging

tyramine has been researched along with Aging in 43 studies

Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.

Research Excerpts

ExcerptRelevanceReference
" Do the changes in brain related to aging also differentially affect these two groups of molecules? In order to check this point, the brain levels of p- and m-octopamine, p-tyramine, noradrenaline, and dopamine, as well as the activities of metabolizing enzymes, were determined in young adult and aging rats (20-26 months)."7.67Effects of aging on p- and m-octopamine, catecholamines, and their metabolizing enzymes in the rat. ( Cavoy, A; Coulon, JF; David, JC; Delacour, J, 1989)
" Norepinephrine was elevated in p75-/- atria, but stimulating norepinephrine release with tyramine produced less tachycardia in p75-/- mice than wild type mice."3.74Regulation of cardiac innervation and function via the p75 neurotrophin receptor. ( Bilimoria, P; Birren, SJ; Gritman, K; Habecker, BA; Linick, C; Lorentz, CU; Woodward, W, 2008)
" To test the hypothesis that octopamine influences honey bee division of labor we treated bees orally with octopamine or its immediate precursor tyramine and determined whether these treatments increased the probability of initiating foraging."3.71Octopamine influences division of labor in honey bee colonies. ( Robinson, GE; Schulz, DJ, 2001)
" Do the changes in brain related to aging also differentially affect these two groups of molecules? In order to check this point, the brain levels of p- and m-octopamine, p-tyramine, noradrenaline, and dopamine, as well as the activities of metabolizing enzymes, were determined in young adult and aging rats (20-26 months)."3.67Effects of aging on p- and m-octopamine, catecholamines, and their metabolizing enzymes in the rat. ( Cavoy, A; Coulon, JF; David, JC; Delacour, J, 1989)
" Bioavailability of tetrahydrobiopterin (BH4), an essential cofactor for catecholamine synthesis, is reduced with aging."2.78Oral sapropterin augments reflex vasoconstriction in aged human skin through noradrenergic mechanisms. ( Alexander, LM; Kenney, WL; Stanhewicz, AE, 2013)
" These data are consistent with the concept that reduced bioavailability of BH(4) and/or tyrosine may impair noradrenaline synthesis and contribute to the attenuated vasoconstrictor response in aged skin."1.36Localized tyrosine or tetrahydrobiopterin supplementation corrects the age-related decline in cutaneous vasoconstriction. ( Holowatz, LA; Kenney, WL; Lang, JA, 2010)
" Local BH(4) supplementation augments reflex and tyramine-induced VC in aged skin, suggesting that reduced BH(4) bioavailability may contribute to attenuated VC during whole-body cooling."1.35Local tetrahydrobiopterin administration augments cutaneous vasoconstriction in aged humans. ( Holowatz, LA; Kenney, WL; Lang, JA, 2009)
"No physiological senile Horner's syndrome was detected."1.28[Age effects of topical tyramine and cocaine on the pupil]. ( Miyashita, Y; Moriya, S; Sugazawa, J; Sugiyama, T; Utsumi, T, 1992)

Research

Studies (43)

TimeframeStudies, this research(%)All Research%
pre-199021 (48.84)18.7374
1990's6 (13.95)18.2507
2000's10 (23.26)29.6817
2010's6 (13.95)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Petrascheck, M1
Ye, X1
Buck, LB1
Stanhewicz, AE1
Alexander, LM1
Kenney, WL3
Nyberg, M1
Piil, P1
Egelund, J1
Sprague, RS1
Mortensen, SP2
Hellsten, Y1
Estep, PW1
Warner, JB1
Bulyk, ML1
Hart, EC1
Joyner, MJ3
Wallin, BG1
Johnson, CP1
Curry, TB1
Eisenach, JH1
Charkoudian, N1
Lang, JA2
Holowatz, LA2
Behrends, A1
Scheiner, R1
Casey, DP1
Padilla, J1
Saltin, B1
Dinenno, FA2
Masuki, S1
Smith, EG1
Voyles, WF1
Kirby, BS1
Markwald, RR1
Donato, AJ1
Švíglerová, J1
Kuncová, J1
Nalos, L1
Slavíková, J1
Stengl, M1
Habecker, BA1
Bilimoria, P1
Linick, C1
Gritman, K1
Lorentz, CU1
Woodward, W1
Birren, SJ1
Bowman, WC1
Osuide, G1
Knehans, AW1
Romsos, DR1
Kiang-Ulrich, M2
Horvath, SM2
Tabsh, K1
Nuwayhid, B1
Murad, S1
Ushioda, E1
Erkkola, R1
Brinkman, CR1
Assali, NS1
Mackenzie, E1
Standen, NB1
Cerrito, F1
Aloisi, G1
Arminio, P1
Cabassi, A1
Bergamaschi, E1
Mutti, A1
Franchini, I1
Borghetti, A1
Slater, M1
Murphy, CR1
Schulz, DJ1
Robinson, GE1
Dalmaz, Y1
Peyrin, L1
Slotkin, TA1
Kuromi, H1
Hasegawa, S1
Davis, AJ1
Holzbauer, M1
Sharman, DF1
Strahan, ME1
Crowe, A1
Morgan, EH1
Snyder, DL1
Aloyo, VJ1
McIlvain, HB1
Johnson, MD1
Roberts, J2
Moriya, S1
Sugiyama, T1
Miyashita, Y1
Sugazawa, J1
Utsumi, T1
Tanaka, H1
Kasuya, Y1
Shigenobu, K1
David, JC1
Coulon, JF1
Cavoy, A1
Delacour, J1
Phillips, MT1
Kirby, ML1
Stewart, DE1
Custer, JR1
Hales, CA1
Kreider, MS1
Goldberg, PB1
Dawes, GS1
Lewis, BV1
Milligan, JE1
Roach, MR1
Talner, NS1
Shibata, S2
Kuchii, M1
Kurahashi, K1
Hattori, K1
Sakurai, I1
Mori, J1
Fujiwara, M1
Leduc, J1
Rivest, P1
Siro-Brigiani, G1
Chieppa, D1
Agrawal, HC1
Glisson, SN1
Himwich, WA1

Reviews

1 review available for tyramine and Aging

ArticleYear
Inefficient functional sympatholysis is an overlooked cause of malperfusion in contracting skeletal muscle.
    The Journal of physiology, 2012, Dec-15, Volume: 590, Issue:24

    Topics: Adenosine Triphosphate; Age Factors; Aging; Animals; Blood Vessels; Cardiovascular Diseases; Energy

2012

Trials

3 trials available for tyramine and Aging

ArticleYear
Oral sapropterin augments reflex vasoconstriction in aged human skin through noradrenergic mechanisms.
    Journal of applied physiology (Bethesda, Md. : 1985), 2013, Oct-01, Volume: 115, Issue:7

    Topics: Aged; Aging; Arterial Pressure; Biopterins; Cross-Over Studies; Double-Blind Method; Female; Humans;

2013
Age-related differences in the sympathetic-hemodynamic balance in men.
    Hypertension (Dallas, Tex. : 1979), 2009, Volume: 54, Issue:1

    Topics: Adrenergic alpha-Agonists; Adult; Aging; Blood Flow Velocity; Cardiac Output; Forearm; Hemodynamics;

2009
Impaired modulation of sympathetic alpha-adrenergic vasoconstriction in contracting forearm muscle of ageing men.
    The Journal of physiology, 2005, Aug-15, Volume: 567, Issue:Pt 1

    Topics: Adenosine; Adrenergic alpha-Agonists; Adult; Aged; Aging; Clonidine; Forearm; Hand Strength; Humans;

2005

Other Studies

39 other studies available for tyramine and Aging

ArticleYear
An antidepressant that extends lifespan in adult Caenorhabditis elegans.
    Nature, 2007, Nov-22, Volume: 450, Issue:7169

    Topics: Aging; Animals; Antidepressive Agents; Caenorhabditis elegans; Caloric Restriction; Humans; Longevit

2007
Effect of PDE5 inhibition on the modulation of sympathetic α-adrenergic vasoconstriction in contracting skeletal muscle of young and older recreationally active humans.
    American journal of physiology. Heart and circulatory physiology, 2015, Dec-01, Volume: 309, Issue:11

    Topics: Adenosine Triphosphate; Age Factors; Aged; Aging; Blood Flow Velocity; Blood Vessels; Humans; Hypere

2015
Short-term calorie restriction in male mice feminizes gene expression and alters key regulators of conserved aging regulatory pathways.
    PloS one, 2009, Volume: 4, Issue:4

    Topics: Aging; Animals; Apoptosis; Caloric Restriction; Carrier Proteins; Cell Cycle; Female; Gene Expressio

2009
Local tetrahydrobiopterin administration augments cutaneous vasoconstriction in aged humans.
    The Journal of physiology, 2009, Aug-01, Volume: 587, Issue:Pt 15

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Aged; Aging; Biopterins; Body Temp

2009
Localized tyrosine or tetrahydrobiopterin supplementation corrects the age-related decline in cutaneous vasoconstriction.
    The Journal of physiology, 2010, Apr-15, Volume: 588, Issue:Pt 8

    Topics: Adrenergic Uptake Inhibitors; Aged; Aging; Biopterins; Dose-Response Relationship, Drug; Female; Hum

2010
Octopamine improves learning in newly emerged bees but not in old foragers.
    The Journal of experimental biology, 2012, Apr-01, Volume: 215, Issue:Pt 7

    Topics: Aging; Animals; Association Learning; Bees; Dopamine; Feeding Behavior; Learning; Octopamine; Seroto

2012
α-adrenergic vasoconstriction contributes to the age-related increase in conduit artery retrograde and oscillatory shear.
    Hypertension (Dallas, Tex. : 1979), 2012, Volume: 60, Issue:4

    Topics: Adrenergic alpha-Antagonists; Adrenergic Uptake Inhibitors; Adult; Aged; Aged, 80 and over; Aging; A

2012
Ageing and leg postjunctional alpha-adrenergic vasoconstrictor responsiveness in healthy men.
    The Journal of physiology, 2007, Jul-01, Volume: 582, Issue:Pt 1

    Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonist

2007
Ageing and vascular adrenoceptor desensitization: too little, too late?
    The Journal of physiology, 2007, Jul-01, Volume: 582, Issue:Pt 1

    Topics: Adrenergic alpha-1 Receptor Agonists; Adrenergic alpha-2 Receptor Agonists; Adrenergic alpha-Agonist

2007
Depressed cardiac contractility and its postnatal development in rats after chemical sympathectomy.
    Physiological research, 2008, Volume: 57, Issue:4

    Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Aging; Animals; Animals, Newborn; Myocardial

2008
Regulation of cardiac innervation and function via the p75 neurotrophin receptor.
    Autonomic neuroscience : basic & clinical, 2008, Volume: 140, Issue:1-2

    Topics: Adrenergic Uptake Inhibitors; Aging; Animals; Cell Differentiation; Growth Cones; Heart; Heart Atria

2008
Effects of tremorine and harmine in the chick.
    European journal of pharmacology, 1967, Volume: 1, Issue:1

    Topics: Acetylcholine; Aging; Animals; Body Temperature; Brain Chemistry; Chickens; Dopamine; Ergothioneine;

1967
Norepinephrine turnover in obese (ob/ob) mice: effects of age, fasting, and acute cold.
    The American journal of physiology, 1983, Volume: 244, Issue:6

    Topics: Adipose Tissue, Brown; Aging; Animals; Cold Temperature; Fasting; Female; Growth; Heart; Hexamethoni

1983
Age-related metabolic modifications in male F344 rats.
    Experimental aging research, 1984,Summer, Volume: 10, Issue:2

    Topics: Aging; Animals; Basal Metabolism; Body Temperature; Male; Oxygen Consumption; Rats; Rats, Inbred F34

1984
Metabolic responses to tyramine and cold in young male Sprague-Dawley and Fischer 344 rats.
    The American journal of physiology, 1984, Volume: 246, Issue:2 Pt 1

    Topics: Acclimatization; Aging; Animals; Body Temperature; Cold Temperature; Colon; Male; Oxygen Consumption

1984
Circulatory effects of chemical sympathectomy in fetal, neonatal, and adult sheep.
    The American journal of physiology, 1982, Volume: 243, Issue:1

    Topics: Acetylcholine; Aging; Animals; Animals, Newborn; Blood Pressure; Cardiovascular Physiological Phenom

1982
The postnatal development of adrenoceptor responses in isolated papillary muscles from rat.
    Pflugers Archiv : European journal of physiology, 1980, Volume: 383, Issue:2

    Topics: Aging; Animals; Animals, Newborn; Female; Heart; In Vitro Techniques; Isoproterenol; Male; Norepinep

1980
Age-related changes in rat brain monoamines release: peculiarity of dopamine release.
    Journal of neuroscience research, 1993, Feb-15, Volume: 34, Issue:3

    Topics: Aging; Amphetamine; Animals; Biogenic Monoamines; Brain Chemistry; Calcimycin; Caudate Nucleus; Cere

1993
Age-related changes in interstitial norepinephrine. A microdialysis study in spontaneously hypertensive rats.
    American journal of hypertension, 1996, Volume: 9, Issue:9

    Topics: Adipose Tissue; Adrenergic alpha-Agonists; Aging; Analysis of Variance; Animals; Hypertension; Male;

1996
Detection of apoptotic DNA damage in prostate hyperplasia using tyramide-amplified avidin-HRP.
    The Histochemical journal, 1999, Volume: 31, Issue:11

    Topics: Aging; Animals; Apoptosis; Avidin; Cell Nucleus; DNA Damage; DNA, Mitochondrial; Horseradish Peroxid

1999
Octopamine influences division of labor in honey bee colonies.
    Journal of comparative physiology. A, Sensory, neural, and behavioral physiology, 2001, Volume: 187, Issue:1

    Topics: Adrenergic alpha-Agonists; Aging; Animals; Bees; Behavior, Animal; Biogenic Amines; Brain Chemistry;

2001
[Relations between urinary 3-methoxytyramine and the peripheral metabolism of dopamine in human adults and children].
    Archives internationales de physiologie et de biochimie, 1978, Volume: 86, Issue:2

    Topics: Adolescent; Adult; Aging; Child; Child, Preschool; Creatinine; Dopamine; Female; Humans; Infant; Inf

1978
Maturation of the adrenal medulla. III. Practical and theoretical considerations of age-dependent alterations in kinetics of incorporation of catecholamines and non-catecholamines.
    Biochemical pharmacology, 1975, Jan-01, Volume: 24, Issue:1

    Topics: Adrenal Glands; Adrenal Medulla; Aging; Amines; Animals; Carbon Radioisotopes; Catecholamines; Epine

1975
Changes in acetylcholine and noradrenaline sensitivity of chick smooth muscle wholly innervated by sympathetic nerve during development.
    European journal of pharmacology, 1975, Volume: 33, Issue:1

    Topics: Acetylcholine; Aging; Animals; Chickens; Cholinesterases; In Vitro Techniques; Muscle Contraction; M

1975
Postnatal development of dopamine deamination in the striatum of the rat.
    British journal of pharmacology, 1975, Volume: 55, Issue:4

    Topics: 3,4-Dihydroxyphenylacetic Acid; Aging; Animals; Corpus Striatum; Deamination; Dopamine; Female; Homo

1975
Iron uptake in relation to transferrin degradation in brain and other tissues of rats.
    The American journal of physiology, 1992, Volume: 263, Issue:4 Pt 2

    Topics: Aging; Animals; Brain; Cellobiose; Female; Femur; Iron; Kidney; Liver; Male; Rats; Rats, Wistar; Ret

1992
Effect of age on potassium- and tyramine-induced release of norepinephrine from cardiac synaptosomes in male F344 rats.
    Journal of gerontology, 1992, Volume: 47, Issue:6

    Topics: Adrenergic Fibers; Aging; Animals; Desipramine; Heart; Male; Myocardium; Norepinephrine; Oxidopamine

1992
[Age effects of topical tyramine and cocaine on the pupil].
    Nippon Ganka Gakkai zasshi, 1992, Volume: 96, Issue:4

    Topics: Adolescent; Adult; Aged; Aging; Child; Cocaine; Horner Syndrome; Humans; Middle Aged; Mydriatics; Op

1992
Altered responsiveness to autonomic transmitters of hearts from neonatal spontaneously hypertensive rats.
    Journal of cardiovascular pharmacology, 1988, Volume: 12, Issue:6

    Topics: Acetylcholine; Aging; Animals; Animals, Newborn; Autonomic Nervous System; Dose-Response Relationshi

1988
Effects of aging on p- and m-octopamine, catecholamines, and their metabolizing enzymes in the rat.
    Journal of neurochemistry, 1989, Volume: 53, Issue:1

    Topics: 2-Hydroxyphenethylamine; Aging; Animals; Aromatic-L-Amino-Acid Decarboxylases; Brain; Catecholamines

1989
Cyclic AMP in normal and sympathetically aneural chick hearts during development.
    Journal of molecular and cellular cardiology, 1986, Volume: 18, Issue:8

    Topics: Adrenergic beta-Antagonists; Aging; Animals; Chick Embryo; Cyclic AMP; Embryonic and Fetal Developme

1986
Chemical sympathectomy decreases alveolar hypoxic vasoconstriction in lambs but not in sheep.
    Journal of applied physiology (Bethesda, Md. : 1985), 1986, Volume: 60, Issue:1

    Topics: Aging; Animals; Animals, Newborn; Blood Pressure; Cardiac Output; Dinoprost; Hydroxydopamines; Hypox

1986
The effect of age on release of norepinephrine by tyramine from rat heart.
    Mechanisms of ageing and development, 1986, Nov-14, Volume: 36, Issue:3

    Topics: Aging; Animals; Heart Rate; In Vitro Techniques; Male; Myocardium; Neuroeffector Junction; Norepinep

1986
Vasomotor responses in the hind limbs of foetal and new-born lambs to asphyxia and aortic chemoreceptor stimulation.
    The Journal of physiology, 1968, Volume: 195, Issue:1

    Topics: Acetylcholine; Aging; Animals; Animals, Newborn; Asphyxia; Atropine; Bradykinin; Chemoreceptor Cells

1968
The supersensitivity of isolated rabbit atria and aortic strips produced by 6-hydroxydopamine.
    European journal of pharmacology, 1972, Volume: 18, Issue:2

    Topics: Aging; Animals; Aorta; Barium; Dimethylphenylpiperazinium Iodide; Dopamine; Drug Interactions; Drug

1972
Adrenergic innervation and cocaine-induced potentiation of adrenergic responses of aortic strips from young and old rabbits.
    The Journal of pharmacology and experimental therapeutics, 1971, Volume: 177, Issue:3

    Topics: Aging; Animals; Aorta, Thoracic; Calcium; Cobalt; Cocaine; Cold Temperature; Drug Synergism; Histocy

1971
[Effects of ablation of interscapular brown fat on cold acclimation in rats].
    Revue canadienne de biologie, 1969, Volume: 28, Issue:1

    Topics: Adaptation, Physiological; Adipose Tissue; Adipose Tissue, Brown; Aging; Animals; Body Temperature R

1969
[The relaxing response of the coronary vessels to sympathic stimuli diminishes with age].
    Bollettino della Societa italiana di biologia sperimentale, 1965, Aug-31, Volume: 41, Issue:16

    Topics: Aging; Animals; Cattle; Coronary Vessels; Epinephrine; Horses; In Vitro Techniques; Isoproterenol; T

1965
Changes in monoamines of rat brain during postnatal ontogeny.
    Biochimica et biophysica acta, 1966, Dec-28, Volume: 130, Issue:2

    Topics: Aging; Animals; Animals, Newborn; Behavior, Animal; Brain; Brain Chemistry; Dopamine; Norepinephrine

1966