Compounds > tyloxapol
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tyloxapol and Hyperlipidemias

tyloxapol has been researched along with Hyperlipidemias in 99 studies

Research

Studies (99)

TimeframeStudies, this research(%)All Research%
pre-199020 (20.20)18.7374
1990's12 (12.12)18.2507
2000's15 (15.15)29.6817
2010's44 (44.44)24.3611
2020's8 (8.08)2.80

Authors

AuthorsStudies
Feng, H; Jin, M; Qin, H; Wang, Q; Wei, Y; Yan, S; Zhang, D; Zhao, L; Zheng, L1
Askın, H; Askın, S; Avcı, B; Demir, Y; Palabıyık, E; Sulumer, AN; Uguz, H1
Amrani, S; Hakmaoui, A; Harnafi, H; Harnafi, M; Milenkovic, D; Mokhtari, C; Mokhtari, I; Moumou, M1
Cai, D; Chen, Y; Gan, H; Hu, Z; Huang, D; Huang, X; Jiang, J; Li, R; Li, Y; Xie, K; Yao, N; Zhan, X1
Ara, J; Haque, SE; Ruqqia, -; Sarwar, G; Sohail, N; Sultana, V; Taj, D1
Alem, C; Bouhlali, EDT; Bourkhis, B; Filali-Zegzouti, Y; Harnafi, H; Hmidani, A; Khouya, T1
Cheng, L; Guo, M; He, Y; Jiang, H; Liu, J; Ren, C; Shi, Y; Sun, M; Wang, B; Wang, W; Wang, X; Xie, Y; Xu, X1
Botelho, FV; de Moura, FBR; de Souza, AV; Espindola, FS; Franco, RR; Justino, AB; Ramos, LPA; Saraiva, AL; Silva, HCG; Tavernelli, N1
Al-Dhabi, NA; Balakrishna, K; Darvin, SS; Esakkimuthu, S; Ignacimuthu, S; Pandikumar, P; Sivasankaran, K; Stalin, A; Toppo, E1
Bucio, L; Cordero-Pérez, P; Galindo-Rodríguez, SA; Leos-Rivas, C; Moreno-Pena, DP; Munoz-Espinosa, LE; Rivas-Morales, C; Viveros-Valdez, JE1
Allgayer, MDC; de Barros Falcão Ferraz, A; de Sousa, JA; Marroni, NP; Pereira, P; Picada, JN1
Bahekar, R; Jain, MR; Joharapurkar, A; Kshirsagar, S; Pandey, D; Patel, D; Patel, HM; Patel, M; Patel, V; Sutariya, B1
Al-Hiari, Y; Al-Qirim, T; Bkhaitan, MM; Hamadneh, L; Kalloush, H; Khalaf, RA; Sheikha, GA1
Chakrabarti, A; Garg, G; Kaushik, N; Pal, A; Patil, A; Praksah, A; Singh, J1
Huang, X; Lan, T; Wu, X; Yan, S1
Aboumair, MS; Abu Sheikha, GM; Abuzaid, HM; Al-Qirim, TM; Ala, SA; Bkhaitan, MM; Jasim, SH; Sabbah, DA; Shattat, GF; Sweidan, KA1
Gonzalez, FJ; Hu, D; Li, F; Xiao, X; Yang, R; Zhang, T; Zhao, Q; Zhu, X1
Chi, G; Feng, H; Han, L; Li, Z; Shen, B; Tian, Y; Wang, Y; Wu, L; Zhang, Q1
Chekir-Ghedira, L; Dhaouefi, Z; Ghedira, K; Kalboussi, Z; Khlifi, R; Kilani-Jaziri, S; Lahmar, A; Maatouk, M1
Baldissera, L; Duarte, SM; Lima, AR; Paula, FB; Pereira, RG; Rodrigues, MR; Silvério, Ados S1
Arya, N; Dwivedi, J; Jagdale, AY; Jain, KS; Munde, MK1
Duraipandiyan, V; Ignacimuthu, S; Irudayaraj, SS; Sunil, C1
Iyer, D; Patil, UK1
Korolenko, TA; Loginova, VM; Tuzikov, FV; Tuzikova, NA1
Arya, N; Coutinho, EC; Dwivedi, J; Jain, KS; Khedkar, VM1
Iyer, D; Patil, UK; Sharma, BK1
Aziz, N; Gilani, AH; Mehmood, MH1
Jo, SP; Kim, JK; Lim, YH1
Ajith, TA; Janardhanan, KK; Nima, N; Rony, KA1
Bhatia, G; Dodda, RP; Palnati, GR; Sashidhara, KV; Sonkar, R1
Ashok, P; Poulose, DN; Singh, D; Suresh, B1
Rekka, EA; Theodosis-Nobelos, P; Tooulia, KK1
Kourounakis, PN; Kourti, M; Rekka, EA; Theodosis-Nobelos, P; Tziona, P1
Abu Farha, R; Abu Shiekha, G; Al-Hiari, Y; Al-Qirim, T; Albashiti, R; Bustanji, Y1
Al-Dhabi, NA; Antony, PJ; Balakrishna, K; Gandhi, GR; Ignacimuthu, S; Sivasankaran, K; Stalin, A; Toppo, E1
Abu Sheikha, G; Al-Essa, L; Al-Hiari, Y; Al-Qirim, T; Azmy, N; Hamadneh, L; Hikmat, S; Shattat, G1
Choi, HY; Ham, I; Lee, J; Lee, KJ; Yang, G1
da Rocha, JT; Nogueira, CW; Sperança, A; Zeni, G1
Bhatia, A; Bhatia, G; Khan, MM; Khanna, AK; Saxena, JK; Sethi, A; Srivastava, S1
Chander, R; Khanna, AK; Kumar, V; Mahdi, AA; Mahdi, F; Saxena, JK; Singh, P; Singh, R; Singh, S; Singh, VK1
Adeneye, AA; Adeyemi, OO; Agbaje, EO1
Al-Hiari, Y; Al-Qirim, T; El-Huneidi, W; Shahwan, M; Shattat, G; Sweidan, K1
Cherkanova, MS; Korolenko, TA; Tuzikov, FV; Tuzikova, NA; Vasil'eva, ED1
Al-Hiari, Y; Al-Qirim, R; Al-Qirim, T; El-Huneidi, W; Shahwan, M; Shattat, G; Sheikha, GA1
Cherkanova, MS; Johnston, TP; Kaledin, VI; Korolenko, TA; Loginova, VM; Tuzikov, FV; Tuzikova, NA1
Ignacimuthu, S; Pandikumar, P; Prakash Babu, N; Saravanan, M1
Ignacimuthu, S; Kumarappan, C; Sunil, C1
Muthukumar, K; Nachiappan, V; Sabarirajan, J; Vijayaraj, P1
Al-Hiari, Y; Al-Qirim, T; El-Huneidi, W; Hikmat, S; Shattat, G; Sheikha, GA1
He, XH; Jia, HY; Li, W; Shi, WG; Zhong, BH1
Brandys, J; Gawlik, M; Gawlik, MB1
Al-Hiari, Y; Al-Kouz, S; Al-Qirim, R; Al-Qirim, T; Hamadneh, L; Hikmat, S; Shattat, G; Sheikha, GA; Sweidan, K1
Cui, JC; Du, TL; He, RR; Hiroshi, K; Huang, XJ; Yao, N; Zeng, XH1
Bhatia, G; Dodda, RP; Khanna, AK; Palnati, GR; Sashidhara, KV; Sonkar, R1
Bhatia, G; Chaturvedi, U; Saxena, JK; Shrivastava, A; Singh, SV1
Ahmad, VU; Ara, J; Qasim, R; Sultana, V1
Hadjipetrou, L; Kourounakis, AP; Kourounakis, PN; Peroulis, N; Stefanou, N; Victoratos, P; Yiangou, M1
HIRSCH, RL; KELLNER, A2
ORIENTE, P; SCANU, A1
COURTICE, FC; GARLICK, DG1
TANAKA, H1
COURTICE, FC; MUNOZ-MARCUS, M1
Mcpherson, JC; Moore, WT; Tidwell, HC1
Dixit, VK; Patil, UK; Saraf, S1
Lee, SJ; Lim, KT; Oh, PS2
Li, F; Sun, JB; Wang, YJ; Zhang, SW1
Amrani, S; Aziz, M; Besco, E; Bouanani, Nel H; Bravo, E; Caid, HS; Harnafi, H; Manfredini, S; Napolitano, M1
Bhatia, G; Faridi, S; Khan, MM; Khanna, AK; Maurya, A; Saxena, JK; Sethi, A; Srivastava, S; Tewari, V1
Kim, DH; Min, SW1
Jain, KS; Kadam, SS; Kathiravan, MK; Kumar, KG; Mahadik, KR; Roy, SK; Shishoo, CJ1
Brunet, C; Cazin, M; Chaoui, A; Delacourte, A; Lesieur, D; Lesieur, I; Luyckx, M1
Chistiakova, AM; Miroshkina, VN; Parfenova, NS; Ryzhenkov, VE; Shanygina, KI1
Dixit, VP; Joshi, S1
Cayen, MN; Dubuc, J; Dvornik, D; Greselin, E; Kallai-Sanfacon, MA1
Kojima, T; Marumo, H; Shuto, K; Tanaka, M; Yamada, K1
Baldwin, JR; Cavestri, RC; Feller, DR; Loh, W; Minatelli, JA; Newman, HA; Sober, CL; Witiak, DT1
Erdman, JW; Gerber, LE1
Ito, T; Shiomi, M1
Alcindor, LG; Antébi, H; Giudicelli, Y; Malagrida, L; Olichon, D; Pecquery, R; Zimmermann, L1
Inoue, Y; Kurogi, Y; Nagao, K; Nakamura, S; Tsuda, Y; Tsutsumi, K; Yoshitsugu, H1
Baczako, K; Büchler, MW; Dervenis, C; Friess, H; Hofbauer, B; Kisling, P; Schilling, M; Uhl, W; Weber, A1
Goto, K; Kondo, M; Morioka, Y; Naito, S; Nakamura, S; Tsutsumi, K1
Alcindor, LG; Antébi, H; Morvan-Bourcier, C; Zimmermann, L1
Aoyama, K; Higuchi, S; Uchida, T; Watanabe, T1
Aragane, K; Kitamine, T; Kusunoki, J; Ohnishi, H; Yamaura, T1
Friedman, M; Hoffman, A; Lomnicky, Y; Luria, MH; Raz, I1
Friedman, M; Gilhar, D; Hoffman, A; Lomnicky, Y; Luria, MH1
Cuparencu, B; Horák, A; Horák, J1
Batra, S; Bhaduri, AP; Chander, R; Joshi, BS; Khanna, AK; Roy, R1
Cuparencu, B; Hâncu, N; Horák, J; Vincze, J1
Chiba, S; Obara, K; Saito, T; Sato, H; Shoji, Y; Soma, J; Yoshinaga, K1
Oguchi, K; Okazaki, M; Suzuki, M1
Ikeda, S; Kusama, H; Nishiyama, M1
Ito, T; Shiomi, M; Watanabe, Y1
Apostolova, Iu; Kavrŭkova, Iu; Kiriakov, A; Tinterova, Z; Vŭlkova, S1
Kasugai, O; Mino, M; Shimizu, T1
Brunet, C; Cazin, M; Delacourte, A; Lesieur, D; Lesieur, I; Lespagnol, C; Luyckx, M; Mallevais, ML1

Other Studies

99 other study(ies) available for tyloxapol and Hyperlipidemias

ArticleYear
Lipopolysaccharide and tyloxapol accelerate the development of atherosclerosis in mice.
    Lipids, 2022, Volume: 57, Issue:2

    Topics: Animals; Atherosclerosis; Hypercholesterolemia; Hyperlipidemias; Inflammation; Lipid Metabolism; Lipopolysaccharides; Liver; Mice; Polyethylene Glycols; Triglycerides

2022
Assessment of hypolipidemic and anti-inflammatory properties of walnut (Juglans regia) seed coat extract and modulates some metabolic enzymes activity in triton WR-1339-induced hyperlipidemia in rat kidney, liver, and heart.
    Journal of molecular recognition : JMR, 2023, Volume: 36, Issue:3

    Topics: Acetylcholinesterase; Animals; Anti-Inflammatory Agents; Butyrylcholinesterase; Hyperlipidemias; Juglans; Kidney; Liver; Plant Extracts; Rats; Seeds

2023
Polyphenol-rich extract from loquat fruit peel prevents hyperlipidemia and hepato-nephrotoxicity in mice:
    Food & function, 2023, Aug-14, Volume: 14, Issue:16

    Topics: Animals; Antioxidants; Hyperlipidemias; Liver; Mice; Molecular Docking Simulation; Oxidative Stress; Plant Extracts; Polyphenols

2023
Tanshinol A Ameliorates Triton-1339W-Induced Hyperlipidemia and Liver Injury in C57BL/6J Mice by Regulating mRNA Expression of Lipemic-Oxidative Injury Genes.
    Lipids, 2020, Volume: 55, Issue:2

    Topics: Animals; Caffeic Acids; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Gene Expression Profiling; Gene Expression Regulation; Gene Regulatory Networks; Hyperlipidemias; Lipid Metabolism; Lipids; Male; Mice; Mice, Inbred C57BL; Oxidative Stress; Polyethylene Glycols; Signal Transduction

2020
Hypolipidemic potential of sterol containing fractions of Jolyna laminarioides: a brown alga.
    Pakistan journal of pharmaceutical sciences, 2020, Volume: 33, Issue:1

    Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Diet, High-Fat; Hyperlipidemias; Hypolipidemic Agents; L-Lactate Dehydrogenase; Male; Phaeophyceae; Plant Extracts; Plant Leaves; Polyethylene Glycols; Rats; Sterols

2020
Effect of Phoenix dactylifera seeds (dates) extract in triton WR-1339 and high fat diet induced hyperlipidaemia in rats: A comparison with simvastatin.
    Journal of ethnopharmacology, 2020, Sep-15, Volume: 259

    Topics: Animals; Antioxidants; Biomarkers; Diet, High-Fat; Disease Models, Animal; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Hypolipidemic Agents; Lipid Peroxidation; Lipids; Male; Obesity; Phoeniceae; Plant Extracts; Polyethylene Glycols; Polyphenols; Rats, Wistar; Seeds; Simvastatin; Solvents; Weight Gain

2020
The combination of sesamol and clofibric acid moieties leads to a novel potent hypolipidemic agent with antioxidant, anti-inflammatory and hepatoprotective activity.
    Bioorganic & medicinal chemistry letters, 2021, 07-15, Volume: 44

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antioxidants; Benzodioxoles; Clofibric Acid; Dose-Response Relationship, Drug; Hyperlipidemias; Hypolipidemic Agents; Inflammation; Liver; Mice; Mice, Inbred Strains; Molecular Docking Simulation; Molecular Structure; Oxidative Stress; Phenols; Polyethylene Glycols; Protective Agents; Structure-Activity Relationship

2021
Antioxidant compounds from Annona crassiflora fruit peel reduce lipid levels and oxidative damage and maintain the glutathione defense in hepatic tissue of Triton WR-1339-induced hyperlipidemic mice.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2021, Volume: 142

    Topics: Animals; Annona; Antioxidants; Cholesterol; Fruit; Glutathione; Hyperlipidemias; Hypolipidemic Agents; Lipid Metabolism; Lipid Peroxidation; Liver; Male; Mice, Inbred C57BL; Oxidative Stress; Oxidoreductases; Plant Extracts; Polyethylene Glycols; Polyphenols; Protein Carbonylation; Triglycerides

2021
Antihyperlipidemic and hepatoprotective effects of Gardenin A in cellular and high fat diet fed rodent models.
    Chemico-biological interactions, 2017, May-01, Volume: 269

    Topics: Animals; Cell Survival; Diet, High-Fat; Flavones; Gardenia; Hep G2 Cells; Humans; Hyperlipidemias; Hypolipidemic Agents; Lipids; Liver; Male; Non-alcoholic Fatty Liver Disease; Oleic Acid; Palmitates; Polyethylene Glycols; Protective Agents; Rats; Rats, Wistar

2017
Evaluation of hypocholesterolemic activity of extracts of Bidens odorata and Brickellia eupatorioides.
    Pakistan journal of pharmaceutical sciences, 2017, Volume: 30, Issue:2(Suppl.)

    Topics: Alanine Transaminase; Animals; Antioxidants; Aspartate Aminotransferases; Asteraceae; Bidens; Cholesterol; Hyperlipidemias; Hypolipidemic Agents; Liver; Male; Plant Extracts; Polyethylene Glycols; Rats; Triglycerides

2017
Evaluation of DNA damage in Wistar rat tissues with hyperlipidemia induced by tyloxapol.
    Experimental and molecular pathology, 2017, Volume: 103, Issue:1

    Topics: Animals; Brain; Cholesterol, HDL; Cholesterol, LDL; Comet Assay; Creatinine; DNA Damage; Genomic Instability; Hyperlipidemias; Hypolipidemic Agents; Kidney; Liver; Male; Micronucleus Tests; Oxidoreductases; Polyethylene Glycols; Rats; Rats, Wistar; Triglycerides; Urea

2017
Balanced Coagonist of GLP-1 and Glucagon Receptors Corrects Dyslipidemia by Improving FGF21 Sensitivity in Hamster Model.
    Drug research, 2017, Volume: 67, Issue:12

    Topics: Adipose Tissue; Aminoisobutyric Acids; Animals; Bile; Cholesterol; Cricetinae; Diet, High-Fat; Dipeptides; Disease Models, Animal; Fibroblast Growth Factors; Glucagon; Glucagon-Like Peptide 1; Homeostasis; Hyperlipidemias; Lipolysis; Liver; Male; Peptide Fragments; Polyethylene Glycols; Receptors, Fibroblast Growth Factor; Receptors, Glucagon; Triglycerides

2017
Synthesis of Novel Benzimidazole-2-carboxamide Derivatives and in Vivo Antihyperlipidemic Activity Evaluation.
    Chemical & pharmaceutical bulletin, 2018, Volume: 66, Issue:4

    Topics: Animals; Benzimidazoles; Disease Models, Animal; Dose-Response Relationship, Drug; Hyperlipidemias; Hypolipidemic Agents; Injections, Intraperitoneal; Male; Molecular Structure; Polyethylene Glycols; Rats; Rats, Wistar; Structure-Activity Relationship

2018
Pharmacological evaluation of Convolvulus pluricaulis as hypolipidaemic agent in Triton WR-1339-induced hyperlipidaemia in rats.
    The Journal of pharmacy and pharmacology, 2018, Volume: 70, Issue:11

    Topics: Animals; Atherosclerosis; Biomarkers; Convolvulus; Disease Models, Animal; Female; Fenofibrate; Hyperlipidemias; Hypolipidemic Agents; Lipids; Male; Oxidative Stress; Plant Extracts; Plaque, Atherosclerotic; Polyethylene Glycols; Rats, Wistar

2018
[Lipid-lowering effect of propolis in mice with Triton-WR1339-induced hyperlipidemia and its mechanism for regulating lipid metabolism].
    Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2018, Jul-30, Volume: 38, Issue:8

    Topics: Animals; Hyperlipidemias; Lipid Metabolism; Lipids; Liver; Mice; Mice, Inbred C57BL; Polyethylene Glycols; Propolis; Random Allocation; Triglycerides

2018
Synthesis and in Vivo Lipid-Lowering Activity of Novel Imidazoles-5-carboxamide Derivatives in Triton-WR-1339-Induced Hyperlipidemic Wistar Rats.
    Chemical & pharmaceutical bulletin, 2018, Volume: 66, Issue:10

    Topics: Animals; Hyperlipidemias; Hypolipidemic Agents; Imidazoles; Intubation, Gastrointestinal; Lipids; Lipoproteins, HDL; Male; Molecular Structure; Polyethylene Glycols; Rats; Rats, Wistar; Solubility

2018
Modulation of Lipid Metabolism by Celastrol.
    Journal of proteome research, 2019, 03-01, Volume: 18, Issue:3

    Topics: 1-Acylglycerophosphocholine O-Acyltransferase; 3T3-L1 Cells; Adipocytes; Animals; Cell Differentiation; Diet, High-Fat; Gene Expression Regulation; Humans; Hyperlipidemias; Lipid Metabolism; Liver; Lysophosphatidylcholines; Mice; Pentacyclic Triterpenes; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipase D; Polyethylene Glycols; Proteasome Inhibitors; Sphingomyelin Phosphodiesterase; Sphingomyelins; Triterpenes

2019
Morin reduces inflammatory responses and alleviates lipid accumulation in hepatocytes.
    Journal of cellular physiology, 2019, Volume: 234, Issue:11

    Topics: Acetyl-CoA Carboxylase; AMP-Activated Protein Kinase Kinases; Animals; Flavonoids; Hep G2 Cells; Hepatocytes; Humans; Hyperlipidemias; Inflammation; Lipid Metabolism; Mice; Non-alcoholic Fatty Liver Disease; Oleic Acid; Phosphorylation; Polyethylene Glycols; PPAR alpha; Protein Kinases; Proto-Oncogene Proteins c-akt; Signal Transduction; Sterol Regulatory Element Binding Protein 1; Triglycerides

2019
Assessment of hypolipidemic, anti-inflammatory and antioxidant properties of medicinal plant Erica multiflora in triton WR-1339-induced hyperlipidemia and liver function repair in rats: A comparison with fenofibrate.
    Regulatory toxicology and pharmacology : RTP, 2019, Volume: 107

    Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Ericaceae; Fenofibrate; Hyperlipidemias; Hypolipidemic Agents; Liver; Male; Phytochemicals; Plant Extracts; Plant Leaves; Polyethylene Glycols; Rats, Wistar

2019
The effects of the decaffeination of coffee samples on platelet aggregation in hyperlipidemic rats.
    Plant foods for human nutrition (Dordrecht, Netherlands), 2013, Volume: 68, Issue:3

    Topics: Animals; Brazil; Caffeine; Chlorogenic Acid; Coffea; Coffee; Food Handling; Hyperlipidemias; Lipids; Male; Partial Thromboplastin Time; Phenols; Platelet Aggregation; Polyethylene Glycols; Prothrombin Time; Rats; Rats, Wistar; Seeds

2013
Design, synthesis, and antihyperlipidemic evaluation of novel 2-[1-(substitutedphenyl)-4-oxo-azetidin-2-yl]-5,6-disubstitutedthieno[2,3-d]pyrimidin-4(3H)-ones.
    Archiv der Pharmazie, 2013, Volume: 346, Issue:8

    Topics: Animals; Azetidines; Biomarkers; Cholesterol; Disease Models, Animal; Drug Design; Gemfibrozil; Hyperlipidemias; Hypolipidemic Agents; Intestinal Absorption; Intestinal Mucosa; Intestines; Molecular Structure; Polyethylene Glycols; Pyrimidinones; Rats; Rats, Wistar; Structure-Activity Relationship; Triglycerides

2013
In vitro antioxidant and antihyperlipidemic activities of Toddalia asiatica (L) Lam. leaves in Triton WR-1339 and high fat diet induced hyperlipidemic rats.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2013, Volume: 60

    Topics: Animals; Antioxidants; Cholesterol, HDL; Cholesterol, LDL; Diet, High-Fat; Hexanes; Hyperlipidemias; Hypolipidemic Agents; Liver; Male; Methanol; Plant Extracts; Plant Leaves; Polyethylene Glycols; Rats; Rats, Wistar; Rutaceae; Triglycerides

2013
Evaluation of antihyperlipidemic and antitumor activities of isolated coumarins from Salvadora indica.
    Pharmaceutical biology, 2014, Volume: 52, Issue:1

    Topics: Animals; Antineoplastic Agents, Phytogenic; Coumarins; Disease Models, Animal; Hyperlipidemias; Hypolipidemic Agents; Male; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Plant Extracts; Polyethylene Glycols; Rats; Salvadoraceae; Skin Neoplasms; Survival Rate

2014
Comparative characteristics of lipemia models induced by injections of Triton WR-1339 and poloxamer 407 in mice.
    Bulletin of experimental biology and medicine, 2013, Volume: 155, Issue:2

    Topics: Animals; Cholesterol; Disease Models, Animal; Hyperlipidemias; Lipoproteins, HDL; Lipoproteins, LDL; Macrophages; Mice; Poloxamer; Polyethylene Glycols; Surface-Active Agents; Triglycerides

2013
Design, synthesis and biological evaluation of some 2-azetidinone derivatives as potential antihyperlipidemic agents.
    Archiv der Pharmazie, 2013, Volume: 346, Issue:12

    Topics: Animals; Azetidines; Binding Sites; Biomarkers; Crystallography, X-Ray; Disease Models, Animal; Drug Design; Ezetimibe; Female; Hyperlipidemias; Hypolipidemic Agents; Lipids; Male; Membrane Proteins; Membrane Transport Proteins; Models, Molecular; Molecular Docking Simulation; Molecular Structure; Polyethylene Glycols; Protein Conformation; Rats; Rats, Wistar

2013
Isolation of bioactive phytoconstituent from Alpinia galanga L. with anti-hyperlipidemic activity.
    Journal of dietary supplements, 2013, Volume: 10, Issue:4

    Topics: Alpinia; Animals; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Dose-Response Relationship, Drug; Female; Furaldehyde; Hyperlipidemias; Hypolipidemic Agents; Lipids; Lipoproteins, LDL; Male; Phytotherapy; Plant Extracts; Polyethylene Glycols; Rats; Rhizome; Triglycerides

2013
Studies on two polyherbal formulations (ZPTO and ZTO) for comparison of their antidyslipidemic, antihypertensive and endothelial modulating activities.
    BMC complementary and alternative medicine, 2013, Dec-26, Volume: 13

    Topics: Analysis of Variance; Animals; Antihypertensive Agents; Antioxidants; Aorta; Blood Glucose; Blood Pressure; Dose-Response Relationship, Drug; Endothelium, Vascular; Hyperlipidemias; Lipid Regulating Agents; Lipids; Magnoliopsida; Mice; Plant Extracts; Polyethylene Glycols; Rats; Rats, Inbred SHR; Rats, Wistar; Vasoconstriction

2013
Antihyperlipidemic effects of stilbenoids isolated from Morus alba in rats fed a high-cholesterol diet.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2014, Volume: 65

    Topics: Animals; Body Weight; Cholesterol, Dietary; Disaccharides; Hyperlipidemias; Hypolipidemic Agents; Lipids; Male; Morus; Plant Extracts; Polyethylene Glycols; Rats; Rats, Sprague-Dawley; Stilbenes

2014
Hypolipidemic activity of Phellinus rimosus against triton WR-1339 and high cholesterol diet induced hyperlipidemic rats.
    Environmental toxicology and pharmacology, 2014, Volume: 37, Issue:2

    Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Basidiomycota; Complex Mixtures; Diet, High-Fat; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Hypolipidemic Agents; Lipids; Liver; Male; Myocardium; Polyethylene Glycols; Rats, Wistar; Thiobarbituric Acid Reactive Substances

2014
Design and synthesis of novel indole-chalcone fibrates as lipid lowering agents.
    European journal of medicinal chemistry, 2014, Jun-23, Volume: 81

    Topics: Animals; Antioxidants; Chalcone; Disease Models, Animal; Drug Design; Hyperlipidemias; Hypolipidemic Agents; Indoles; Lipoproteins; Lipoproteins, HDL; Lipoproteins, LDL; Male; Molecular Structure; Polyethylene Glycols; Rats

2014
Evaluation of antihyperlipidemic potency of a polyherbomineral formulation (AF-LIP) in experimental animal models.
    Pakistan journal of biological sciences : PJBS, 2014, Feb-01, Volume: 17, Issue:3

    Topics: Acyl Coenzyme A; Animals; Atherosclerosis; Cholesterol; Diet, High-Fat; Dose-Response Relationship, Drug; Feces; Female; Fenofibrate; Hyperlipidemias; Hypolipidemic Agents; Lipoproteins; Male; Plant Extracts; Polyethylene Glycols; Rats; Rats, Wistar; Simvastatin

2014
Thiomorpholine Derivatives with Hypolipidemic and Antioxidant Activity.
    Archiv der Pharmazie, 2015, Volume: 348, Issue:9

    Topics: Animals; Anticholesteremic Agents; Antioxidants; Biomarkers; Cholesterol; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Design; Enzyme Inhibitors; Farnesyl-Diphosphate Farnesyltransferase; Hyperlipidemias; Lipid Peroxidation; Lipoproteins, LDL; Molecular Structure; Morpholines; Polyethylene Glycols; Rats; Structure-Activity Relationship; Triglycerides

2015
Esters of some non-steroidal anti-inflammatory drugs with cinnamyl alcohol are potent lipoxygenase inhibitors with enhanced anti-inflammatory activity.
    Bioorganic & medicinal chemistry letters, 2015, Nov-15, Volume: 25, Issue:22

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cinnamates; Edema; Esters; Glycine max; Hyperlipidemias; Indoleacetic Acids; Lipoxygenase Inhibitors; Polyethylene Glycols; Propanols; Propionates; Rats; Thioctic Acid

2015
Lipid lowering activity of novel N-(benzoylphenyl)pyridine-3-carboxamide derivatives in Triton WR-1339-induced hyperlipidemic rats.
    Journal of enzyme inhibition and medicinal chemistry, 2016, Volume: 31, Issue:sup4

    Topics: Animals; Antihyperkalemic Agents; Disease Models, Animal; Hyperlipidemias; Lipids; Male; Molecular Structure; Polyethylene Glycols; Pyridines; Rats; Rats, Wistar

2016
Myoinositol ameliorates high-fat diet and streptozotocin-induced diabetes in rats through promoting insulin receptor signaling.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 88

    Topics: Administration, Oral; Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Diet, High-Fat; Drinking Behavior; Fasting; Feeding Behavior; Gene Expression Regulation; Glucose Tolerance Test; Hyperlipidemias; Immunohistochemistry; Inositol; Insulin; Insulin Resistance; Kidney; Lipids; Liver; Male; Molecular Docking Simulation; Polyethylene Glycols; Rats, Wistar; Receptor, Insulin; RNA, Messenger; Signal Transduction

2017
N-(3-Benzoylphenyl)-1H-Indole-2-Carboxamide decreases triglyceride levels by downregulation of Apoc3 gene expression in acute hyperlipidemic rat model.
    Molecular and cellular biochemistry, 2017, Volume: 431, Issue:1-2

    Topics: Animals; Apolipoprotein C-III; Disease Models, Animal; Down-Regulation; Hyperlipidemias; Imidazoles; Male; Polyethylene Glycols; Rats; Rats, Sprague-Dawley; Triglycerides

2017
Hypolipidemic effect of MeOH extract of Bambusae Caulis in Taeniam in hyperlipidemia induced by Triton WR-1339 and high cholesterol diet in rats.
    Immunopharmacology and immunotoxicology, 2009, Volume: 31, Issue:3

    Topics: Animals; Cholesterol; Detergents; Diet; Hyperlipidemias; Hypolipidemic Agents; Male; Plant Extracts; Poaceae; Polyethylene Glycols; Rats; Rats, Sprague-Dawley

2009
Hypolipidaemic activity of orally administered diphenyl diselenide in Triton WR-1339-induced hyperlipidaemia in mice.
    The Journal of pharmacy and pharmacology, 2009, Volume: 61, Issue:12

    Topics: Animals; Benzene Derivatives; Cholesterol; Hyperlipidemias; Hypolipidemic Agents; Liver; Male; Mice; Organoselenium Compounds; Polyethylene Glycols; Selenium; Triglycerides

2009
Pregnane glycoside from Hemidesmus indicus as a potential anti-oxidant and anti-dyslipidemic agent.
    Natural product research, 2010, Volume: 24, Issue:15

    Topics: Animals; Antioxidants; Glycosides; Hemidesmus; Hyperlipidemias; Hypolipidemic Agents; Magnetic Resonance Spectroscopy; Male; Polyethylene Glycols; Pregnanes; Rats

2010
Hypolipidemic activity of Hibiscus rosa sinensis root in rats.
    Indian journal of biochemistry & biophysics, 2009, Volume: 46, Issue:6

    Topics: Animals; Cholesterol; Dietary Fats; Hibiscus; Hyperlipidemias; Hypolipidemic Agents; Liver; Male; Phytotherapy; Plant Extracts; Plant Roots; Polyethylene Glycols; Rats

2009
Anti-obesity and antihyperlipidaemic effect of Hunteria umbellata seed extract in experimental hyperlipidaemia.
    Journal of ethnopharmacology, 2010, Jul-20, Volume: 130, Issue:2

    Topics: Administration, Oral; Animals; Anti-Obesity Agents; Apocynaceae; Cardiovascular Diseases; Disease Models, Animal; Dose-Response Relationship, Drug; Feeding Behavior; Female; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Hypolipidemic Agents; Lipids; Liver; Male; Olive Oil; Plant Extracts; Plant Oils; Polyethylene Glycols; Rats; Rats, Wistar; Seeds; Simvastatin; Time Factors; Weight Gain

2010
The hypolipidemic activity of novel benzofuran-2-carboxamide derivatives in Triton WR-1339-induced hyperlipidemic rats: a comparison with bezafibrate.
    Journal of enzyme inhibition and medicinal chemistry, 2010, Volume: 25, Issue:6

    Topics: Animals; Anthracenes; Atherosclerosis; Benzofurans; Bezafibrate; Cholesterol; Cholesterol, HDL; Detergents; Drug Design; Hyperlipidemias; Hypolipidemic Agents; Lipids; Male; Molecular Structure; Polyethylene Glycols; Random Allocation; Rats; Rats, Wistar; Time Factors; Triglycerides

2010
Fractional composition of blood serum lipoproteins in mice and rats with Triton WR 1339-induced lipemia.
    Bulletin of experimental biology and medicine, 2010, Volume: 149, Issue:5

    Topics: Animals; Atherosclerosis; Cholesterol; Cholesterol, VLDL; Disease Models, Animal; Female; Hyperlipidemias; Lipoproteins; Lipoproteins, LDL; Mice; Mice, Inbred ICR; Polyethylene Glycols; Rats; Rats, Wistar; Triglycerides

2010
Synthesis and anti-hyperlipidemic evaluation of N‑(benzoylphenyl)-5-fluoro-1H-indole-2-carboxamide derivatives in Triton WR-1339-induced hyperlipidemic rats.
    Molecules (Basel, Switzerland), 2010, Aug-26, Volume: 15, Issue:9

    Topics: Animals; Bezafibrate; Cholesterol, HDL; Hyperlipidemias; Hypolipidemic Agents; Indoles; Male; Polyethylene Glycols; Rats; Rats, Wistar; Structure-Activity Relationship

2010
Influence of atorvastatin on fractional and subfractional composition of serum lipoproteins and MMP activity in mice with Triton WR 1339-induced lipaemia.
    The Journal of pharmacy and pharmacology, 2011, Volume: 63, Issue:6

    Topics: Animals; Anti-Inflammatory Agents; Atorvastatin; Cholesterol; Heptanoic Acids; Hyperlipidemias; Hypolipidemic Agents; Lipoproteins; Liver; Male; Matrix Metalloproteinases; Mice; Mice, Inbred ICR; Polyethylene Glycols; Pyrroles; Scattering, Small Angle; Triglycerides; X-Ray Diffraction

2011
Antihyperlipidemic activity of Ichnocarpus frutescens in triton WR-1339-induced and high-fat diet animals.
    Pharmaceutical biology, 2011, Volume: 49, Issue:10

    Topics: Administration, Oral; Animals; Apocynaceae; Cholesterol; Detergents; Diet, High-Fat; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Hyperlipidemias; Hypolipidemic Agents; Lipids; Male; Mice; Obesity; Phytotherapy; Plant Extracts; Plant Leaves; Polyethylene Glycols; Rats; Rats, Wistar; Triglycerides

2011
Hypolipidemic activity of Symplocos cochinchinensis S. Moore leaves in hyperlipidemic rats.
    Journal of natural medicines, 2012, Volume: 66, Issue:1

    Topics: Animals; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Chromatography, High Pressure Liquid; Diet, High-Fat; Disease Models, Animal; Dose-Response Relationship, Drug; Fenofibrate; Hexanes; Hyperlipidemias; Hypolipidemic Agents; Lipids; Liver; Magnoliopsida; Male; Plant Extracts; Plant Leaves; Polyethylene Glycols; Rats; Rats, Wistar; Solvents; Triglycerides

2012
Antihyperlipidemic activity of Cassia auriculata flowers in triton WR 1339 induced hyperlipidemic rats.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 2013, Volume: 65, Issue:1-2

    Topics: Animals; Antioxidants; Blood Glucose; Cassia; Cholesterol; Flowers; Hyperlipidemias; Hypolipidemic Agents; Lipid Peroxidation; Male; Oxidative Stress; Plant Extracts; Polyethylene Glycols; Rats; Rats, Wistar; Triglycerides

2013
Antihyperlipidemic properties of novel N-(benzoylphenyl)-5-substituted-1H-indole-2-carboxamides in Triton WR-1339-induced hyperlipidemic rats.
    Molecules (Basel, Switzerland), 2011, Sep-29, Volume: 16, Issue:10

    Topics: Animals; Bezafibrate; Cholesterol, HDL; Hyperlipidemias; Hypolipidemic Agents; Indoles; Male; Polyethylene Glycols; Rats; Rats, Wistar; Triglycerides

2011
Novel phenoxyalkylcarboxylic acid derivatives as hypolipidaemic agents.
    Journal of enzyme inhibition and medicinal chemistry, 2012, Volume: 27, Issue:2

    Topics: Animals; Carboxylic Acids; Cholesterol; Diabetes Mellitus, Experimental; Fenofibrate; Flavonoids; Hyperlipidemias; Hypolipidemic Agents; Magnetic Resonance Spectroscopy; Male; Mice; Models, Molecular; Molecular Structure; Polyethylene Glycols; Resveratrol; Stilbenes; Surface-Active Agents; Triglycerides

2012
The impact of Triton WR-1339 induced hyperlipidemia on the effects of benzo(a)pyrene or guaiacol on α- and γ-tocopherol pools and selected markers of pro-/antioxidative balance in rat plasma and erythrocytes.
    Environmental toxicology and pharmacology, 2012, Volume: 33, Issue:3

    Topics: alpha-Tocopherol; Animals; Benzo(a)pyrene; Carcinogens; Erythrocytes; gamma-Tocopherol; Guaiacol; Hyperlipidemias; Lipid Peroxidation; Lipids; Male; Malondialdehyde; Polyethylene Glycols; Rats; Rats, Wistar; Superoxide Dismutase; Surface-Active Agents

2012
The pharmacological effects of novel 5-fluoro-N-(9,10-dihydro-9,10-dioxoanthracen-8-yl)-1H-indole-2-carboxamide derivatives on plasma lipid profile of Triton-WR-1339-induced Wistar rats.
    Journal of enzyme inhibition and medicinal chemistry, 2013, Volume: 28, Issue:4

    Topics: Animals; Anthraquinones; Dose-Response Relationship, Drug; Hyperlipidemias; Hypolipidemic Agents; Indoles; Lipids; Male; Molecular Structure; Polyethylene Glycols; Rats; Rats, Wistar

2013
Hypotriglyceridemic effects of apple polyphenols extract via up-regulation of lipoprotein lipase in triton WR-1339-induced mice.
    Chinese journal of integrative medicine, 2014, Volume: 20, Issue:1

    Topics: Animals; Chlorogenic Acid; Cholesterol; Flavonoids; Hyperlipidemias; Hypolipidemic Agents; Lipoprotein Lipase; Male; Mice; Phytotherapy; Polyethylene Glycols; PPAR alpha; RNA, Messenger; Tannins; Triglycerides; Up-Regulation

2014
Discovery of amide based fibrates as possible antidyslipidemic and antioxidant agents.
    European journal of medicinal chemistry, 2012, Volume: 57

    Topics: Amides; Animals; Antioxidants; Enzyme Activation; Fibric Acids; Free Radicals; Hyperlipidemias; Hypolipidemic Agents; Lipid Peroxidation; Lipoprotein Lipase; Male; Polyethylene Glycols; Rats; Structure-Activity Relationship

2012
Lipid lowering and antioxidant effect of miglitol in triton treated hyperlipidemic and high fat diet induced obese rats.
    Lipids, 2013, Volume: 48, Issue:6

    Topics: 1-Deoxynojirimycin; 3T3-L1 Cells; Adipogenesis; Animals; Antioxidants; Body Weight; Diet, High-Fat; Eating; Hyperlipidemias; Hypoglycemic Agents; Lipids; Liver; Male; Mice; Obesity; Polyethylene Glycols; Rats

2013
Hypolipidaemic activity of seaweed from Karachi coast.
    Phytotherapy research : PTR, 2002, Volume: 16, Issue:5

    Topics: Administration, Oral; Animals; Dietary Fats; Disease Models, Animal; Hyperlipidemias; Hypolipidemic Agents; Male; Pakistan; Phytotherapy; Plant Extracts; Polyethylene Glycols; Rats; Seaweed

2002
Experimental hyperlipidemia and the effect of NSAIDs.
    Experimental and molecular pathology, 2002, Volume: 73, Issue:2

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cholesterol; Cholesterol, LDL; Cyclooxygenase Inhibitors; Detergents; Female; Hyperlipidemias; Injections, Intraperitoneal; Male; Polyethylene Glycols; Rats; Rats, Inbred F344; Triglycerides

2002
The pathogenesis of hyperlipemia induced by means of surface-active agents. I. Increased total body cholesterol in mice given triton WR 1339 parenterally.
    The Journal of experimental medicine, 1956, Jul-01, Volume: 104, Issue:1

    Topics: Animals; Cholesterol; Hyperlipidemias; Lipid Metabolism; Mice; Polyethylene Glycols; Surface-Active Agents

1956
The pathogenesis of hyperlipemia induced by means of surface-active agents. II. Failure of exchange of cholesterol between the plasma and the liver in rabbits given triton WR 1339.
    The Journal of experimental medicine, 1956, Jul-01, Volume: 104, Issue:1

    Topics: Animals; Blood; Cholesterol; Hypercholesterolemia; Hyperlipidemias; Lipid Metabolism; Lipoproteins; Liver; Plasma; Polyethylene Glycols; Rabbits; Surface-Active Agents

1956
Triton hyperlipemia in dogs. I. In vitro effects of the detergent on serum lipoproteins and chylomcrons.
    The Journal of experimental medicine, 1961, Apr-01, Volume: 113

    Topics: Animals; Detergents; Dogs; Hyperlipidemias; In Vitro Techniques; Lipids; Lipoproteins; Polyethylene Glycols; Proteins; Surface-Active Agents; Triglycerides; Ultracentrifugation

1961
The composition of the lipoproteins in the plasma of rabbits with hypercholesterolaemia or triton WR-1339-induced hyperlipaemia.
    Quarterly journal of experimental physiology and cognate medical sciences, 1962, Volume: 47

    Topics: Animals; Cholesterol; Hypercholesterolemia; Hyperlipidemias; Lipids; Lipoproteins; Polyethylene Glycols; Rabbits; Surface-Active Agents

1962
Study on tuberculostatic activities of body fluids of rabbits given triton WR 1339 with special reference to the role of lipemia.
    Acta tuberculosea Japonica, 1962, Sep-28, Volume: 12

    Topics: Animals; Body Fluids; Hyperlipidemias; Lipids; Polyethylene Glycols; Rabbits; Surface-Active Agents; Tuberculosis

1962
THE COMPOSITION OF THE PLASMA LIPOPROTEINS IN EXPERIMENTAL HYPERLIPAEMIA INDUCED BY TRITON WR-1339, CORTISONE, ALLOXAN AND HAEMORRHAGE IN RABBITS.
    Quarterly journal of experimental physiology and cognate medical sciences, 1964, Volume: 49

    Topics: Alloxan; Animals; Blood Proteins; Cholesterol; Cortisone; Hemorrhage; Hyperlipidemias; Lipoproteins; Pharmacology; Polyethylene Glycols; Rabbits; Research; Surface-Active Agents

1964
THE FATE OF CHYLOMICRONS IN RATS TREATED WITH TRITON WR-1339.
    The American journal of clinical nutrition, 1965, Volume: 16

    Topics: Blood Chemical Analysis; Carbon Isotopes; Chylomicrons; Dietary Fats; Emulsions; Fatty Acids; Hyperlipidemias; Lipid Metabolism; Lipids; Lipoproteins; Palmitic Acid; Pharmacology; Polyethylene Glycols; Rats; Research; Surface-Active Agents; Toxicology; Zea mays

1965
Hypolipidemic activity of seeds of Cassia tora Linn.
    Journal of ethnopharmacology, 2004, Volume: 90, Issue:2-3

    Topics: Animals; Cassia; Female; Hyperlipidemias; Hypolipidemic Agents; Male; Phytotherapy; Plant Extracts; Polyethylene Glycols; Rats; Rats, Wistar; Seeds

2004
Hypolipidemic and antioxidative effects of the plant glycoprotein (36 kDa) from Rhus verniciflua stokes fruit in Triton WR-1339-induced hyperlipidemic mice.
    Bioscience, biotechnology, and biochemistry, 2006, Volume: 70, Issue:2

    Topics: Acyl Coenzyme A; Animals; Antioxidants; Cholesterol; Fruit; Glycoproteins; Hyperlipidemias; Lipid Peroxidation; Male; Mice; Mice, Inbred ICR; Molecular Weight; Nitric Oxide; Phytotherapy; Polyethylene Glycols; Rhus

2006
Hyperlipidemia intensifies cerulein-induced acute pancreatitis associated with activation of protein kinase C in rats.
    World journal of gastroenterology, 2006, May-14, Volume: 12, Issue:18

    Topics: Acute Disease; Amylases; Animals; Apoptosis; Ascites; Ceruletide; Enzyme Activation; Hyperlipidemias; In Situ Nick-End Labeling; Lipids; Male; Organ Size; Pancreas; Pancreatitis; Polyethylene Glycols; Protein Kinase C; Rats; Rats, Sprague-Dawley

2006
Hepatoprotective and hypolipidaemic effects of glycoprotein isolated from Gardenia jasminoides ellis in mice.
    Clinical and experimental pharmacology & physiology, 2006, Volume: 33, Issue:10

    Topics: Animals; Antioxidants; Carbon Tetrachloride; Corn Oil; Cytochromes c; Drug Evaluation, Preclinical; Gardenia; Glycoproteins; Hyperlipidemias; Hypolipidemic Agents; L-Lactate Dehydrogenase; Lipid Peroxidation; Liver; Male; Mice; Mice, Inbred ICR; NF-kappa B; Nitric Oxide; Polyethylene Glycols; Reactive Oxygen Species; Thiobarbituric Acid Reactive Substances; Transcription Factor AP-1

2006
Hypolipidaemic activity of aqueous Ocimum basilicum extract in acute hyperlipidaemia induced by triton WR-1339 in rats and its antioxidant property.
    Phytotherapy research : PTR, 2006, Volume: 20, Issue:12

    Topics: Animals; Antioxidants; Cholesterol, HDL; Cholesterol, LDL; Female; Fenofibrate; Hyperlipidemias; Hypolipidemic Agents; Ocimum basilicum; Plant Extracts; Polyethylene Glycols; Rats; Rats, Wistar

2006
Expeditious and convenient synthesis of pregnanes and its glycosides as potential anti-dyslipidemic and anti-oxidant agents.
    Bioorganic & medicinal chemistry, 2007, Jul-01, Volume: 15, Issue:13

    Topics: Animals; Antioxidants; Cholesterol; Glycosides; Hyperlipidemias; Hypolipidemic Agents; Indicators and Reagents; Male; Malondialdehyde; Phospholipids; Polyethylene Glycols; Pregnanes; Rats; Superoxides; Triglycerides

2007
Kakkalide and irisolidone: HMG-CoA reductase inhibitors isolated from the flower of Pueraria thunbergiana.
    Biological & pharmaceutical bulletin, 2007, Volume: 30, Issue:10

    Topics: Animals; Cholesterol; Cholesterol, HDL; Flavonoids; Flowers; Glycosides; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Isoflavones; Male; Mice; Mice, Inbred ICR; Plant Extracts; Polyethylene Glycols; Pueraria; Rats; Rats, Sprague-Dawley; Spectrometry, Mass, Fast Atom Bombardment; Surface-Active Agents; Triglycerides

2007
Synthesis and antihyperlipidemic activity of some novel condensed 2-chloroalkyl-4-chloro/hydroxy-5,6-disubstituted pyrimidines.
    Arzneimittel-Forschung, 2007, Volume: 57, Issue:9

    Topics: Alkanes; Animals; Chemical Phenomena; Chemistry, Physical; Cholesterol; Gemfibrozil; Hyperlipidemias; Hypolipidemic Agents; Indicators and Reagents; Magnetic Resonance Spectroscopy; Polyethylene Glycols; Pyrimidines; Quantitative Structure-Activity Relationship; Rats; Rats, Wistar; Triglycerides

2007
Preliminary note: effect of microtubule inhibitors with acrylophenone structure on Triton WR 1339 induced hyperlipidemia in rats.
    Methods and findings in experimental and clinical pharmacology, 1984, Volume: 6, Issue:5

    Topics: Acrylates; Animals; Cholesterol; Colchicine; Hyperlipidemias; Male; Microtubules; Polyethylene Glycols; Rats; Rats, Inbred Strains; Triglycerides

1984
[Effect of arginine on the lipid and lipoprotein content of animal blood].
    Voprosy meditsinskoi khimii, 1984, Volume: 30, Issue:6

    Topics: Animals; Arginine; Cholesterol; Electrophoresis, Polyacrylamide Gel; Guinea Pigs; Hyperlipidemias; Lipids; Lipoproteins; Male; Polyethylene Glycols; Rabbits; Rats; Triglycerides

1984
Effect of Aloe barbedensis & clofibrate on serum lipids in triton-induced hyperlipidaemia in Presbytis monkeys.
    The Indian journal of medical research, 1983, Volume: 78

    Topics: Aloe; Animals; Cercopithecidae; Clofibrate; Hyperlipidemias; Lipids; Male; Plants, Medicinal; Polyethylene Glycols

1983
Evaluation of the lipid-lowering activity of AY-25,712 in rats.
    Atherosclerosis, 1982, Volume: 45, Issue:3

    Topics: Animals; Bile Acids and Salts; Cholesterol; Diabetes Mellitus, Experimental; Furans; Glycerolphosphate Dehydrogenase; Hyperlipidemias; Hypolipidemic Agents; Lipids; Liver; Male; Polyethylene Glycols; Rats; Rats, Inbred Strains

1982
Lipid-lowering effects of N-[4-methylbenzylthiocarbonyl]-L-phenylalanine (KF1492), a new phenylalanine derivative.
    Journal of pharmacobio-dynamics, 1982, Volume: 5, Issue:8

    Topics: Animals; Cholesterol; Clofibrate; Diet; Glycerol; Hyperlipidemias; Hypolipidemic Agents; Male; Phenylalanine; Polyethylene Glycols; Rats; Rats, Inbred Strains; Thiouracil

1982
Antilipidemic activity of 4-oxo-functionalized ethyl 6-chlorochroman-2-carboxylate analogs and a related tricyclic lactone in three rat models.
    Lipids, 1981, Volume: 16, Issue:1

    Topics: Animals; Anticholesteremic Agents; Benzopyrans; Chromans; Chromones; Clofibrate; Disease Models, Animal; Hydroxymethylglutaryl CoA Reductases; Hyperlipidemias; Hypolipidemic Agents; Liver; Male; Polyethylene Glycols; Rats; Structure-Activity Relationship; Sucrose; Triglycerides

1981
Hyperlipidemia in rats fed retinoic acid.
    Lipids, 1981, Volume: 16, Issue:7

    Topics: Animals; Cholesterol; Hyperlipidemias; Lipoprotein Lipase; Lipoproteins, HDL; Lipoproteins, LDL; Lipoproteins, VLDL; Male; Phospholipids; Polyethylene Glycols; Rats; Tretinoin; Triglycerides

1981
Pravastatin sodium, a competitive inhibitor of hepatic 3-hydroxy-3-methylglutaryl coenzyme A reductase, decreases the cholesterol content of newly secreted very-low-density lipoprotein in Watanabe heritable hyperlipidemic rabbits.
    Metabolism: clinical and experimental, 1994, Volume: 43, Issue:5

    Topics: Animals; Cholesterol; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperlipidemias; Injections, Intravenous; Lipids; Lipoproteins; Lipoproteins, VLDL; Liver; Male; Particle Size; Polyethylene Glycols; Pravastatin; Rabbits

1994
Weak resistance to oxidation of native lipoproteins in Wistar rats.
    Annals of nutrition & metabolism, 1993, Volume: 37, Issue:2

    Topics: Animals; Ascorbic Acid; Fatty Acids; Hyperlipidemias; Lipids; Lipoproteins; Male; Oxidation-Reduction; Polyethylene Glycols; Rats; Rats, Wistar; Surface-Active Agents; Vitamin E

1993
Synthesis and hypolipidemic activities of novel 2-[4-[diethoxyphosphoryl)methyl]phenyl]quinazolines and 4(3H)-quinazolinones.
    Journal of medicinal chemistry, 1996, Mar-29, Volume: 39, Issue:7

    Topics: Animals; Arteriosclerosis; Benzamides; Biological Availability; Cholesterol; Chromatography, High Pressure Liquid; Hyperlipidemias; Hypolipidemic Agents; Magnetic Resonance Spectroscopy; Molecular Structure; Organophosphorus Compounds; Polyethylene Glycols; Quinazolines; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Triglycerides

1996
Hyperlipaemia intensifies the course of acute oedematous and acute necrotising pancreatitis in the rat.
    Gut, 1996, Volume: 38, Issue:5

    Topics: Acute Disease; Amylases; Animals; Cholesterol; Disease Models, Animal; Disease Progression; Edema; Hyperlipidemias; Lipase; Male; Necrosis; Pancreatitis; Polyethylene Glycols; Rats; Rats, Wistar; Surface-Active Agents; Triglycerides

1996
Synthesis and biological activity of the metabolites of diethyl 4-[(4-bromo-2-cyanophenyl)carbamoyl]benzylphosphonate (NO-1886).
    Chemical & pharmaceutical bulletin, 1996, Volume: 44, Issue:3

    Topics: Animals; Benzamides; Biotransformation; Chromatography, High Pressure Liquid; Enzyme Inhibitors; Hyperlipidemias; Lipoprotein Lipase; Magnetic Resonance Spectroscopy; Male; Organophosphorus Compounds; Polyethylene Glycols; Rats; Rats, Sprague-Dawley; Triglycerides

1996
[In vitro peroxidation of plasma and erythrocyte lipids during WR-1339 induced hyperlipidemia in Wistar rats].
    Annales pharmaceutiques francaises, 1997, Volume: 55, Issue:6

    Topics: Animals; Ascorbic Acid; Disease Models, Animal; Erythrocytes; Fatty Acids; Humans; Hyperlipidemias; In Vitro Techniques; Lipid Peroxidation; Lipids; Male; Polyethylene Glycols; Rats; Rats, Wistar; Surface-Active Agents; Vitamin E

1997
Relationship between bioavailability and hypocholesterolemic activity of YM17E, an inhibitor of ACAT, in cholesterol-fed rats.
    Atherosclerosis, 1998, Volume: 137, Issue:1

    Topics: Animals; Anticholesteremic Agents; Biological Availability; Cholesterol; Cholesterol Esters; Cholesterol, Dietary; Data Interpretation, Statistical; Diet, Atherogenic; Digestive System; Digestive System Physiological Phenomena; Dose-Response Relationship, Drug; Enzyme Inhibitors; Hyperlipidemias; Intestinal Absorption; Iodine Radioisotopes; Lipoproteins, LDL; Liver; Male; Metabolic Clearance Rate; Phenylurea Compounds; Polyethylene Glycols; Rats; Rats, Sprague-Dawley; Sterol O-Acyltransferase; Surface-Active Agents; Tissue Distribution

1998
Effects of F-1394, an acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor, on ACAT activity in HepG2 cells and on hepatic secretion of lipids in Triton WR-1339-induced hyperlipidemic rats: possible role of hepatic ACAT in very low density lipoprotein se
    Japanese journal of pharmacology, 1998, Volume: 76, Issue:3

    Topics: Animals; Anticholesteremic Agents; Cell Line; Cyclohexanes; Dioxanes; Enzyme Inhibitors; Humans; Hyperlipidemias; Lipid Metabolism; Lipoproteins, VLDL; Liver; Polyethylene Glycols; Rats; Sterol O-Acyltransferase

1998
The effect of the mode of administration on the hypolipidaemic activity of niacin: continuous gastrointestinal administration of low-dose niacin improves lipid-lowering efficacy in experimentally-induced hyperlipidaemic rats.
    The Journal of pharmacy and pharmacology, 1998, Volume: 50, Issue:11

    Topics: Animals; Aspartate Aminotransferases; Cholesterol; Cholesterol, Dietary; Drug Administration Schedule; Duodenum; Hyperlipidemias; In Vitro Techniques; Injections, Intravenous; Intubation, Gastrointestinal; Lipoproteins, HDL; Male; Niacin; Polyethylene Glycols; Rats; Surface-Active Agents; Time Factors; Triglycerides

1998
Improved lipid lowering activity of bezafibrate following continuous gastrointestinal administration: pharmacodynamic rationale for sustained release preparation of the drug.
    Pharmaceutical research, 1999, Volume: 16, Issue:7

    Topics: Animals; Bezafibrate; Cholesterol; Cholesterol, Dietary; Cholesterol, HDL; Delayed-Action Preparations; Disease Models, Animal; Drug Administration Routes; Duodenum; Enzyme Inhibitors; Hyperlipidemias; Hypolipidemic Agents; Lipase; Lipids; Lipoproteins, HDL; Male; Polyethylene Glycols; Rats; Rats, Inbred Lew; Surface-Active Agents

1999
Acute effects of zopiclone on blood glucose level and serum lipids in hyperlipidemic rats. Interactions with PK 11195 and flumazenil.
    Acta physiologica Hungarica, 2000, Volume: 87, Issue:2

    Topics: Animals; Azabicyclo Compounds; Blood Glucose; Central Nervous System; Cholesterol; Flumazenil; GABA Modulators; Hyperlipidemias; Hypnotics and Sedatives; Isoquinolines; Lipids; Male; Peripheral Nervous System; Piperazines; Polyethylene Glycols; Rats; Rats, Wistar; Receptors, GABA-A; Triglycerides

2000
Syntheses and biological evaluation of alkanediamines as antioxidant and hypolipidemic agents.
    Bioorganic & medicinal chemistry, 2001, Volume: 9, Issue:12

    Topics: Alkenes; Animals; Antioxidants; Biochemistry; Diamines; Drug Evaluation, Preclinical; Heparin; Humans; Hydroxyl Radical; Hyperlipidemias; Hypolipidemic Agents; Male; Polyethylene Glycols; Rats

2001
Effects of the hypolipidaemic benzodiazepine derivatives on plasma viscosity in Triton WR-1339 induced hyperlipidaemia in rats.
    Agressologie: revue internationale de physio-biologie et de pharmacologie appliquees aux effets de l'agression, 1979, Volume: 20, Issue:3

    Topics: Animals; Benzodiazepines; Blood Viscosity; Drug Interactions; Hyperlipidemias; Hypolipidemic Agents; Male; Polyethylene Glycols; Rats

1979
Administration of Triton WR 1339 aggravates chronic aminonucleoside nephrosis.
    Nephron, 1992, Volume: 60, Issue:1

    Topics: Animals; Cholesterol; Chronic Disease; Disease Models, Animal; Drug Synergism; Hyperlipidemias; Injections, Intravenous; Lipid Metabolism; Male; Nephrosis; Polyethylene Glycols; Puromycin Aminonucleoside; Rats; Rats, Inbred Strains; Triglycerides

1992
Changes in coagulative and fibrinolytic activities in Triton WR-1339-induced hyperlipidemia in rats.
    Japanese journal of pharmacology, 1990, Volume: 52, Issue:2

    Topics: alpha-2-Antiplasmin; Animals; Antithrombin III; Blood Cell Count; Blood Coagulation; Cholesterol; Factor XIII; Fibrinogen; Fibrinolysis; Hyperlipidemias; Lipids; Male; Partial Thromboplastin Time; Plasminogen; Polyethylene Glycols; Prothrombin Time; Rats; Rats, Inbred Strains

1990
[Pharmacological investigation of bezafibrate, a hypolipidemic agent (1). Effects of bezafibrate on normal and experimental hyperlipidemia in rats].
    Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1988, Volume: 92, Issue:3

    Topics: Administration, Oral; Animals; Bezafibrate; Cholesterol, Dietary; Depression, Chemical; Fructose; Hyperlipidemias; Male; Polyethylene Glycols; Rats; Triglycerides

1988
Increase in hepatic low-density lipoprotein receptor activity during pregnancy in Watanabe heritable hyperlipidemic rabbits; an animal model for familial hypercholesterolemia.
    Biochimica et biophysica acta, 1987, Jan-13, Volume: 917, Issue:1

    Topics: Animals; Cholesterol; Disease Models, Animal; Ethinyl Estradiol; Female; Hyperlipidemias; Hyperlipoproteinemia Type II; Infertility, Female; Kinetics; Lipoproteins; Lipoproteins, LDL; Liver; Phospholipids; Polyethylene Glycols; Pregnancy; Pregnancy Complications; Rabbits; Receptors, LDL; Triglycerides

1987
[In vivo effects of triton WR 1339 on plasma lipoproteins and the postheparin activity of lipoprotein lipase and liver triglyceride lipase (triton hyperlipidemia in rabbits)].
    Eksperimentalna meditsina i morfologiia, 1985, Volume: 24, Issue:4

    Topics: Animals; Detergents; Heparin; Hyperlipidemias; Lipase; Lipolysis; Lipoprotein Lipase; Lipoproteins; Liver; Male; Polyethylene Glycols; Rabbits; Surface-Active Agents; Time Factors

1985
Red blood cell tocopherol and liver tocopherol in hyperlipemic rats as compared with plasma tocopherol.
    Lipids, 1985, Volume: 20, Issue:7

    Topics: Animals; Detergents; Erythrocytes; Hyperlipidemias; Liver; Male; Polyethylene Glycols; Rats; Rats, Inbred Strains; Vitamin E

1985
Pharmacological study of nine antimicrotubular drugs with acrylophenone structure on Triton WR 1339-induced hyperlipidemia in rats.
    Methods and findings in experimental and clinical pharmacology, 1985, Volume: 7, Issue:11

    Topics: Animals; Cholesterol, HDL; Hyperlipidemias; Hypolipidemic Agents; Male; Microtubules; Phospholipids; Polyethylene Glycols; Propiophenones; Rats; Rats, Inbred Strains; Triglycerides

1985