Page last updated: 2024-08-17

tubercidin and Disease Models, Animal

tubercidin has been researched along with Disease Models, Animal in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19902 (8.00)18.7374
1990's5 (20.00)18.2507
2000's10 (40.00)29.6817
2010's8 (32.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cao, X; Chen, J; Fan, L; Liu, P; Qiu, S; Xu, Y; Yu, L; Zhang, M; Zhang, X1
Faingold, CL; Kommajosyula, SP; Randall, ME1
Bourderioux, A; Doležal, D; Džubák, P; Elbert, T; Hajdúch, M; Harvanová, M; Hlaváč, J; Hocek, M; Motyka, K; Nauš, P; Nová, A; Perlíková, P; Rylová, G; Šiller, M; Slavětínská, LP; Tloušťová, E; Znojek, P1
Kaptein, SJ; Marques, RE; Neyts, J; Schols, D; Verbeken, E; Zmurko, J1
Faingold, CL; Kommajosyula, SP; Randall, M1
Blair, IA; Gong, W; Huang, Y; Lorent, K; Mañoral-Mobias, R; Matthews, RP; Murray, IV; Pack, M1
Boison, D; Li, T; Shen, HY1
Fukuda, M; Hino, H; Ishii, E; Kuzume, K; Morimoto, T; Suzuki, Y1
Abe, H; Chayama, K; Hayes, CN; Hiraga, N; Hirata, D; Imamura, M; Iwao, E; Kamiya, N; Kawaoka, T; Kono, T; Mitsui, F; Ochi, H; Ohara, E; Onishi, M; Takahashi, S; Tanaka, S; Tateno, C; Tsuge, M; Yamada, I; Yoshizato, K1
Braun-Dullaeus, RC; Dietrich, S; Haberbosch, W; Kummer, W; Leithaeuser, B; Matthias, RF; Schoaff, MJ; Seay, U; Sedding, DG; Tillmanns, H; Walker, G1
Bohle, RM; Braun-Dullaeus, RC; Dreyer, T; Fink, L; Haberbosch, W; Jeide, I; Langheinrich, AC; Schilling, R; Tammoscheit, K; Walker, G1
Boison, D; Fritschy, JM; Gouder, N; Scheurer, L1
Ashline, D; Milhalik, S; Ortiz, D; Rogers, E; Shea, TB1
Boison, D; Crestani, F; Fedele, DE; Gabernet, L; Gouder, N; Güttinger, M; Rülicke, T; Scheurer, L1
Graves, M; Ortiz, D; Rogers, E; Shea, TB; Tchantchou, F1
Flamand, M; Liu, W; Schul, W; Vasudevan, SG; Xu, HY1
Bea, F; Blessing, E; Isermann, B; Katus, HA; Kreuzer, J; Pedal, I; Preusch, MR; Rosenfeld, ME; Yang, SH1
Carneiro, FS; Carneiro, ZN; Giachini, FRC; Inscho, EW; Leite, R; Lima, VV; Tostes, RC; Webb, RC1
Cha, S; Diop, D; el Kouni, MH1
Bullough, DA; Montag, A; Mullane, KM; Young, MA; Zhang, C1
Poon, A; Sawynok, J1
Jarvis, MF; Kowaluk, EA; Lynch, JJ1
Bray, M; Huggins, J; Zhang, ZX1
Bohle, RM; Braun-Dullaeus, RC; Dennhauser, E; Dreyer, T; Haberbosch, W; Kreuzer, J; Langheinrich, AC; Tillmanns, H; Walker, G1
De Clercq, E; Robins, MJ1

Other Studies

25 other study(ies) available for tubercidin and Disease Models, Animal

ArticleYear
EZH2 inhibitor DZNep modulates microglial activation and protects against ischaemic brain injury after experimental stroke.
    European journal of pharmacology, 2019, Aug-15, Volume: 857

    Topics: Animals; Apoptosis; Disease Models, Animal; Enhancer of Zeste Homolog 2 Protein; Infarction, Middle Cerebral Artery; Male; Mice; Mice, Inbred C57BL; Microglia; Neuroprotective Agents; Reperfusion Injury; STAT3 Transcription Factor; Tubercidin; Up-Regulation

2019
Inhibition of adenosine metabolism induces changes in post-ictal depression, respiration, and mortality in genetically epilepsy prone rats.
    Epilepsy research, 2016, Volume: 119

    Topics: Adenine; Adenosine; Animals; Blood Gas Analysis; Brugada Syndrome; Disease Models, Animal; Enzyme Inhibitors; Epilepsy; Female; Genetic Predisposition to Disease; Incidence; Male; Oxygen; Rats; Respiration; Respiration Disorders; Seizures; Sex Characteristics; Tubercidin

2016
7-(2-Thienyl)-7-Deazaadenosine (AB61), a New Potent Nucleoside Cytostatic with a Complex Mode of Action.
    Molecular cancer therapeutics, 2016, Volume: 15, Issue:5

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Membrane Permeability; Cell Proliferation; Disease Models, Animal; DNA; DNA Damage; Fibroblasts; Gene Expression Regulation, Neoplastic; Humans; Mice; Neoplasms; Protein Biosynthesis; Protein Folding; RNA, Messenger; Survival Analysis; Treatment Outcome; Tubercidin; Xenograft Model Antitumor Assays

2016
The Viral Polymerase Inhibitor 7-Deaza-2'-C-Methyladenosine Is a Potent Inhibitor of In Vitro Zika Virus Replication and Delays Disease Progression in a Robust Mouse Infection Model.
    PLoS neglected tropical diseases, 2016, Volume: 10, Issue:5

    Topics: Animals; Antiviral Agents; Chlorocebus aethiops; Disease Models, Animal; Male; Mice; Tubercidin; Vero Cells; Virus Replication; Zika Virus; Zika Virus Infection

2016
Susceptibility to seizure-induced sudden death in DBA/2 mice is altered by adenosine.
    Epilepsy research, 2016, Volume: 124

    Topics: Adenosine; Animals; Caffeine; Death, Sudden; Disease Models, Animal; Disease Susceptibility; Dose-Response Relationship, Drug; Female; Male; Mice, Inbred DBA; Purinergic P1 Receptor Antagonists; Pyrazoles; Pyrimidines; Receptors, Purinergic P1; Respiration; Respiration Disorders; Seizures; Tubercidin; Xanthines

2016
TNFalpha-dependent hepatic steatosis and liver degeneration caused by mutation of zebrafish S-adenosylhomocysteine hydrolase.
    Development (Cambridge, England), 2009, Volume: 136, Issue:5

    Topics: Adenosylhomocysteinase; Animals; Base Sequence; Disease Models, Animal; DNA Primers; Fatty Liver; Humans; Larva; Lipogenesis; Liver Diseases; Male; Methionine; Mitochondria, Liver; Models, Biological; Mutation; Oxidative Stress; Phenotype; Species Specificity; Tubercidin; Tumor Necrosis Factor-alpha; Zebrafish; Zebrafish Proteins

2009
A novel mouse model for sudden unexpected death in epilepsy (SUDEP): role of impaired adenosine clearance.
    Epilepsia, 2010, Volume: 51, Issue:3

    Topics: Adenine; Adenosine; Adenosine Deaminase Inhibitors; Adenosine Kinase; Animals; Caffeine; Cause of Death; Death, Sudden; Disease Models, Animal; Enzyme Inhibitors; Epilepsy; Kainic Acid; Mice; Purinergic P1 Receptor Antagonists; Receptors, Purinergic P1; Risk Factors; Seizures; Survival Analysis; Tubercidin

2010
Adenosine A1 receptor blockage mediates theophylline-associated seizures.
    Epilepsia, 2010, Volume: 51, Issue:3

    Topics: Adenosine; Adenosine A1 Receptor Agonists; Adenosine A1 Receptor Antagonists; Adenosine Kinase; Animals; Behavior, Animal; Body Temperature; Brain; Disease Models, Animal; Dose-Response Relationship, Drug; Electroencephalography; Enzyme Inhibitors; Hyperthermia, Induced; Injections, Intraperitoneal; Male; Rats; Rats, Inbred Lew; Seizures; Theophylline; Tubercidin

2010
Elimination of hepatitis C virus by short term NS3-4A and NS5B inhibitor combination therapy in human hepatocyte chimeric mice.
    Journal of hepatology, 2011, Volume: 54, Issue:5

    Topics: Animals; Antiviral Agents; Cells, Cultured; Chimerism; Disease Models, Animal; Drug Therapy, Combination; Hepacivirus; Hepatitis C, Chronic; Hepatocytes; Humans; Mice; Mice, SCID; Oligopeptides; Tubercidin; Viral Nonstructural Proteins; Virus Replication

2011
Protective effect of 3-deazaadenosine in a rat model of lipopolysaccharide-induced myocardial dysfunction.
    Shock (Augusta, Ga.), 2003, Volume: 19, Issue:3

    Topics: Animals; Cell Adhesion Molecules; Disease Models, Animal; Gene Expression Regulation; Heart; Isomerism; Lipopolysaccharides; Male; Myocardium; Rats; Rats, Wistar; Sepsis; Tubercidin

2003
Effects of 3-deazaadenosine on homocysteine and atherosclerosis in apolipoprotein E-deficient mice.
    Atherosclerosis, 2003, Volume: 171, Issue:2

    Topics: Analysis of Variance; Animals; Apolipoproteins E; Arteriosclerosis; Base Sequence; Biopsy, Needle; Cholesterol; Diet, Atherogenic; Disease Models, Animal; DNA, Complementary; Flow Cytometry; Homocysteine; Immunohistochemistry; Male; Mice; Mice, Knockout; Molecular Sequence Data; Polymerase Chain Reaction; Probability; Reference Values; RNA, Messenger; Sinus of Valsalva; Transaminases; Tubercidin; Tunica Intima

2003
Overexpression of adenosine kinase in epileptic hippocampus contributes to epileptogenesis.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2004, Jan-21, Volume: 24, Issue:3

    Topics: Action Potentials; Adenosine A1 Receptor Antagonists; Adenosine Kinase; Animals; Anticonvulsants; Astrocytes; Brain; Disease Models, Animal; Disease Progression; Electroencephalography; Enzyme Inhibitors; Epilepsy, Temporal Lobe; Glial Fibrillary Acidic Protein; Hippocampus; Immunohistochemistry; Kainic Acid; Mice; Neurons; Tubercidin; Xanthines

2004
The S-adenosyl homocysteine hydrolase inhibitor 3-deaza-adenosine prevents oxidative damage and cognitive impairment following folate and vitamin E deprivation in a murine model of age-related, oxidative stress-induced neurodegeneration.
    Neuromolecular medicine, 2004, Volume: 5, Issue:2

    Topics: Adenosylhomocysteinase; Animals; Apolipoproteins E; Brain; Brain Chemistry; Cognition Disorders; Disease Models, Animal; Down-Regulation; Enzyme Inhibitors; Female; Folic Acid Deficiency; Homocysteine; Male; Methionine; Mice; Mice, Knockout; Neurodegenerative Diseases; Neuroprotective Agents; Oxidative Stress; Tubercidin; Vitamin E Deficiency

2004
Astrogliosis in epilepsy leads to overexpression of adenosine kinase, resulting in seizure aggravation.
    Brain : a journal of neurology, 2005, Volume: 128, Issue:Pt 10

    Topics: Adenosine Kinase; Animals; Astrocytes; Behavior, Animal; Brain; Cerebral Cortex; Disease Models, Animal; Electroencephalography; Enzyme Inhibitors; Epilepsy, Temporal Lobe; Gliosis; Hippocampus; Kainic Acid; Locomotion; Male; Mice; Mice, Transgenic; Neurons; Transgenes; Tubercidin; Up-Regulation

2005
Dietary supplementation with 3-deaza adenosine, N-acetyl cysteine, and S-adenosyl methionine provide neuroprotection against multiple consequences of vitamin deficiency and oxidative challenge: relevance to age-related neurodegeneration.
    Neuromolecular medicine, 2004, Volume: 6, Issue:2-3

    Topics: Acetylcysteine; Animals; Apolipoproteins E; Cell Line, Tumor; Dietary Supplements; Disease Models, Animal; Folic Acid Deficiency; Glutathione; Glutathione Synthase; Maze Learning; Mice; Mice, Knockout; Neuroblastoma; Neuroprotective Agents; Oxidative Stress; S-Adenosylmethionine; Thiobarbituric Acid Reactive Substances; Tubercidin; Vitamin E Deficiency

2004
A dengue fever viremia model in mice shows reduction in viral replication and suppression of the inflammatory response after treatment with antiviral drugs.
    The Journal of infectious diseases, 2007, Mar-01, Volume: 195, Issue:5

    Topics: 1-Deoxynojirimycin; Animals; Antiviral Agents; Dengue; Disease Models, Animal; Dose-Response Relationship, Drug; Indolizines; Mice; Ribavirin; Time Factors; Tubercidin; Viremia; Virus Replication

2007
Long-term administration of 3-deazaadenosine does not alter progression of advanced atherosclerotic lesions in apolipoprotein E-deficient mice.
    Journal of cardiovascular pharmacology, 2007, Volume: 50, Issue:2

    Topics: Actins; Adenosine; Animals; Aorta, Thoracic; Apolipoproteins E; Atherosclerosis; Disease Models, Animal; Electrophoretic Mobility Shift Assay; Female; Homocysteine; Intercellular Adhesion Molecule-1; Interleukin-10; Interleukin-1beta; Mice; Mice, Inbred C57BL; Mice, Knockout; NF-kappa B; Transcription Factor AP-1; Tubercidin; Vascular Cell Adhesion Molecule-1

2007
Adenosine actions are preserved in corpus cavernosum from obese and type II diabetic db/db mouse.
    The journal of sexual medicine, 2008, Volume: 5, Issue:5

    Topics: Acetylcholine; Adenosine; Adenosine Kinase; Animals; Diabetes Mellitus, Type 2; Dipyridamole; Disease Models, Animal; Electric Stimulation; Enzyme Inhibitors; Male; Mice; Mice, Mutant Strains; Mice, Obese; Muscle Contraction; Muscle, Smooth; Nitroprusside; Penis; Phenylephrine; Phosphodiesterase Inhibitors; Tubercidin; Vasoconstrictor Agents; Vasodilator Agents

2008
Combination therapy of schistosomiasis by tubercidin and nitrobenzylthioinosine 5'-monophosphate.
    Proceedings of the National Academy of Sciences of the United States of America, 1983, Volume: 80, Issue:21

    Topics: Animals; Biological Transport; Disease Models, Animal; Drug Therapy, Combination; Female; Inosine; Mice; Ribonucleosides; Schistosomiasis; Thioinosine; Thionucleotides; Tubercidin

1983
Adenosine-mediated inhibition of platelet aggregation by acadesine. A novel antithrombotic mechanism in vitro and in vivo.
    The Journal of clinical investigation, 1994, Volume: 94, Issue:4

    Topics: Adenosine; Adenosine Deaminase; Adenosine Kinase; Aminoimidazole Carboxamide; Animals; Aspirin; Blood Physiological Phenomena; Coronary Thrombosis; Coronary Vessels; Dipyridamole; Disease Models, Animal; Dogs; Erythrocytes; Humans; Male; Plasma; Platelet Aggregation; Purinergic P1 Receptor Antagonists; Regional Blood Flow; Ribonucleosides; Theophylline; Tubercidin

1994
Antinociception by adenosine analogs and inhibitors of adenosine metabolism in an inflammatory thermal hyperalgesia model in the rat.
    Pain, 1998, Volume: 74, Issue:2-3

    Topics: Adenosine; Adenosine Deaminase; Animals; Antihypertensive Agents; Carrageenan; Deoxyadenosines; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Edema; Enzyme Inhibitors; Excipients; Hot Temperature; Hyperalgesia; Male; Neuritis; Neurons; Nociceptors; Pentostatin; Phenethylamines; Purinergic P1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Tubercidin

1998
An adenosine kinase inhibitor attenuates tactile allodynia in a rat model of diabetic neuropathic pain.
    European journal of pharmacology, 1999, Jan-08, Volume: 364, Issue:2-3

    Topics: Adenosine Kinase; Animals; Anti-Bacterial Agents; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Male; Morphine; Narcotics; Pain; Pain Threshold; Rats; Rats, Sprague-Dawley; Streptozocin; Theophylline; Tubercidin

1999
Antiviral drug therapy of filovirus infections: S-adenosylhomocysteine hydrolase inhibitors inhibit Ebola virus in vitro and in a lethal mouse model.
    The Journal of infectious diseases, 1999, Volume: 179 Suppl 1

    Topics: Adenosylhomocysteinase; Animals; Antiviral Agents; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation; Drug Evaluation, Preclinical; Ebolavirus; Enzyme Inhibitors; Hemorrhagic Fever, Ebola; Hydrolases; In Vitro Techniques; Liver; Mice; Mice, Inbred BALB C; Spleen; Time Factors; Tubercidin; Vero Cells

1999
3-deazaadenosine prevents adhesion molecule expression and atherosclerotic lesion formation in the aortas of C57BL/6J mice.
    Arteriosclerosis, thrombosis, and vascular biology, 1999, Volume: 19, Issue:11

    Topics: Animals; Aorta, Thoracic; Arteriosclerosis; Cell Adhesion; Diet, Atherogenic; Disease Models, Animal; Female; Hypercholesterolemia; Intercellular Adhesion Molecule-1; Macrophages; Mice; Mice, Inbred C57BL; Monocytes; Tubercidin; Tunica Intima; Vascular Cell Adhesion Molecule-1

1999
Xylotubercidin against herpes simplex virus type 2 in mice.
    Antimicrobial agents and chemotherapy, 1986, Volume: 30, Issue:5

    Topics: Acyclovir; Animals; Antiviral Agents; Disease Models, Animal; Herpes Simplex; Mice; Mice, Inbred Strains; Ribonucleosides; Tubercidin

1986