tubastatin-a has been researched along with Melanoma* in 2 studies
2 other study(ies) available for tubastatin-a and Melanoma
| Article | Year |
|---|---|
Rational Design of Suprastat: A Novel Selective Histone Deacetylase 6 Inhibitor with the Ability to Potentiate Immunotherapy in Melanoma Models.
Selective inhibition of histone deacetylase 6 (HDAC6) is being recognized as a therapeutic approach for cancers. In this study, we designed a new HDAC6 inhibitor, named Suprastat, using Topics: Animals; Cell Line, Tumor; Crystallography, X-Ray; Drug Design; Female; Histone Deacetylase 6; Histone Deacetylase Inhibitors; Humans; Hydrogen Bonding; Hydroxamic Acids; Immunologic Factors; Immunotherapy; Melanoma; Mice, Inbred C57BL; Microsomes, Liver; Molecular Dynamics Simulation; Phenylurea Compounds; Protein Binding; Rats | 2020 |
Discovery of a New Isoxazole-3-hydroxamate-Based Histone Deacetylase 6 Inhibitor SS-208 with Antitumor Activity in Syngeneic Melanoma Mouse Models.
Topics: Animals; Catalytic Domain; CD8-Positive T-Lymphocytes; Cell Line, Tumor; Drug Discovery; Histone Deacetylase 6; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Isoxazoles; Macrophages; Melanoma; Mice; Microsomes; Natural Killer T-Cells; Transplantation, Isogeneic; Zebrafish; Zinc | 2019 |