tubastatin-a has been researched along with Arthritis--Rheumatoid* in 1 studies
1 other study(ies) available for tubastatin-a and Arthritis--Rheumatoid
| Article | Year |
|---|---|
Marbostat-100 Defines a New Class of Potent and Selective Antiinflammatory and Antirheumatic Histone Deacetylase 6 Inhibitors.
Epigenetic modifiers of the histone deacetylase (HDAC) family contribute to autoimmunity, cancer, HIV infection, inflammation, and neurodegeneration. Hence, histone deacetylase inhibitors (HDACi), which alter protein acetylation, gene expression patterns, and cell fate decisions, represent promising new drugs for the therapy of these diseases. Whereas pan-HDACi inhibit all 11 Zn Topics: Animals; Anti-Inflammatory Agents; Antirheumatic Agents; Arthritis, Experimental; Arthritis, Rheumatoid; Benzamides; Binding Sites; Carbolines; Cell Line, Tumor; Collagen Type II; HEK293 Cells; Histone Deacetylase 6; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Male; Mice, Inbred DBA; Molecular Docking Simulation; Zebrafish | 2018 |