tryptophan and Schizophrenia

tryptophan has been researched along with Schizophrenia in 232 studies

Research

Studies (232)

TimeframeStudies, this research(%)All Research%
pre-1990144 (62.07)18.7374
1990's15 (6.47)18.2507
2000's20 (8.62)29.6817
2010's38 (16.38)24.3611
2020's15 (6.47)2.80

Authors

AuthorsStudies
Butler, MI; Clarke, G; Cryan, JF; Dinan, TG; Long-Smith, C; Moloney, GM; Morkl, S; O'Mahony, SM1
Al-Hakeim, HK; Almulla, AF; Maes, M; Solmi, M; Tunvirachaisakul, C; Vasupanrajit, A; Verkerk, R1
Maes, M1
Guo, L; He, H; Li, R; Liu, JC; Shi, QQ; Yu, H; Zhou, CH1
Adhikari, BM; Buchanan, RW; Chen, S; Hare, SM; Kane-Gerard, S; Kelly, DL; Mo, C; Notarangelo, FM; Rowland, LM; Sathyasaikumar, KV; Schwarcz, R; Seneviratne, C; Wijtenburg, SA1
Chen, J; Fang, X; Ling, Y; Liu, S; Su, KP; Tang, W; Wang, G; Wang, Y; Yang, Y; Zhang, C; Zhang, X; Zhou, C1
Brix, S; Chen, C; Chen, Y; Dang, Y; Fan, Y; Gao, C; Guo, L; Guo, R; He, X; Jia, H; Jie, Z; Ju, Y; Kristiansen, K; Liu, B; Ma, Q; Ma, X; Madsen, L; Sun, Q; Wang, J; Wang, Q; Wang, W; Xiao, L; Xie, Y; Xu, X; Yang, H; Yang, L; Yang, Z; Zhang, T; Zhao, B; Zhu, F1
Barbosa, DS; Geffard, M; Kanchanatawan, B; Maes, M; Michelin, AP; Moreira, EG; Semeão, LO; Sirivichayakul, S; Vojdani, A1
Fan, N; Lu, H; Luo, Y; Ni, X; Wen, Y; Zhang, M; Zhang, Z1
Coppens, V; De Picker, L; Kampen, JK; Morrens, M1
Cao, B; Chen, Y; McIntyre, RS; Pan, Z; Ren, Z; Wang, D1
Chiappelli, J; Cui, Y; Hong, LE; Huang, J; Kochunov, P; Tan, S; Tan, Y; Tian, B; Tian, L; Tong, J; Wang, Z; Yang, F; Zhang, P; Zhou, Y1
Cathomas, F; Guetter, K; Kaiser, S; Klaus, F; Seifritz, E1
Bartoli, F; Callovini, T; Carrà, G; Cavaleri, D; Cioni, RM; Crocamo, C1
Miller, BJ; Wang, AK1
Anderson, G; Carvalho, AF; Galecki, P; Kanchanatawan, B; Maes, M; Sirivichayakul, S1
Anderson, G; Carvalho, AF; Geffard, M; Hemrungrojn, S; Kanchanatawan, B; Maes, M; Ruxrungtham, K; Sirivichayakul, S; Thika, S1
Costa, AC; Gattaz, WF; Joaquim, HPG; Talib, LL1
Carvalho, AF; Geffard, M; Kanchanatawan, B; Maes, M; Sirivichayakul, S; Sriswasdi, S; Stoyanov, D; Thika, S1
Kanchanatawan, B; Maes, M1
Guadagno, E; Li, C; Ramamurthy, J; Trakadis, Y; Wang, A; Wang, C; Zhang, E1
Carvalho, AF; Kanchanatawan, B; Maes, M; Sirivichayakul, S; Thika, S1
Kanchanatawan, B; Maes, M; Sriswasdi, S1
Fujigaki, H; Mouri, A; Nabeshima, T; Saito, K; Yamamoto, Y1
Baldessarini, RJ; Comparelli, A; Corigliano, V; Curto, M; Fazio, F; Ferracuti, S; Lionetto, L; Nicoletti, F; Simmaco, M1
Agartz, I; Andreassen, OA; Bogdanov, M; Dieset, I; Djurovic, S; Hope, S; Jönsson, EG; Kaddurah-Daouk, R; Matson, W; Melle, I; Smeland, OB; Steen, NE; Vedal, TSJ1
Bhat, M; Blennow, K; Cannon, TD; Engberg, G; Erhardt, S; Hultman, CM; Johansson, V; Kegel, M; Landén, M; Schwieler, L; Wetterberg, L; Zetterberg, H1
Flegr, J1
Aoyama, Y; Fukushima, T; Ichiba, H; Iizuka, H; Koshikawa, M; Matsumoto, Y; Nabeshima, T; Watanabe, S1
Dippel, C; Krause, D; Müller, N; Myint, AM; Riedel, M; Schwarz, MJ; Weidinger, E1
Banister, SD; Guillemin, GJ; Karl, T; Kassiou, M; Lim, CK; Purves-Tyson, T; Weickert, CS; Zavitsanou, K1
Gabaeva, MV; Ganisheva, TK; Golimbet, VE; Kasparov, SV; Kolesina, NIu; Korovaĭtseva, GI; Savel'eva, TM; Snegireva, AA; Velikaia, NV1
Abdelmoaty, S; Bhat, M; Dahl, ML; Engberg, G; Erhardt, S; Finn, A; Kegel, ME; Larsson, MK; Lundberg, K; Orhan, F; Samuelsson, M; Schuppe-Koistinen, I; Schwieler, L; Sellgren, C; Skogh, E; Svensson, C1
De Picker, L; Dedeurwaerdere, S; Kosten, L; Staelens, S; Stroobants, S; Thomae, D; Van Eetveldt, A; Verhaeghe, J; Verkerk, R; Wyffels, L1
Can, A; Chiappelli, J; Du, X; Fuchs, D; Hong, LE; Kochunov, P; Lowry, CA; Postolache, TT; Rowland, LM; Savransky, A; Shukla, DK; Tagamets, M; Wijtenburg, SA1
Fukuwatari, T; Kuroki, Y; Mori, N; Sekine, A; Urata, T1
Brenner, LA; Cook, TB; Eaton, WW; Friedl, M; Fuchs, D; Giegling, I; Groer, M; Hartmann, AM; Hoisington, AJ; Kelly, DL; Konte, B; Lowry, CA; Okusaga, O; Pandey, JP; Postolache, TT; Reeves, G; Rujescu, D; Stearns-Yoder, KA1
Cordeiro, RC; da Silva Araújo, T; de Freitas Lima, R; de Jesus Souza Machado, M; Freitas de Lucena, D; Isabelle de Góis Queiroz, A; Macêdo, D; Maes, M; Maia Chaves Filho, AJ; Monte, AS1
Bhat, M; Cannon, TD; Engberg, G; Erhardt, S; Hultman, CM; Johansson, V; Kegel, ME; Landén, M; Schuppe-Koistinen, I; Schwieler, L; Wetterberg, L1
Anderson, G; Carvalho, AF; Geffard, M; Ivanova, R; Kanchanatawan, B; Maes, M; Noto, C; Ruxrungtham, K; Sirivichayakul, S; Thika, S1
Anderson, G; Carvalho, AF; Geffard, M; Kanchanatawan, B; Maes, M; Ruxrungtham, K; Sirivichayakul, S1
Barry, S; Clarke, G; Dinan, TG; Scully, P1
Alexander, J; Brett, R; Henriquez, SA; Pratt, J; Roberts, CW1
Costantino, G1
Kim, YK; Leonard, B; Myint, AM; Scharpe, S; Steinbusch, H; Verkerk, R1
Dougherty, GG; Kaddurah-Daouk, R; Keshavan, MS; Krishnan, RR; Matson, WR; McEvoy, J; Montrose, DM; Reddy, RD; Rozen, S; Yao, JK1
Derakhshandeh, S; Farrashbandi, H; Saadat, I; Saadat, M1
Bechter, K; Fuchs, D; Herzog, S; Maxeiner, HG; Reiber, H; Tumani, H1
Dai, J; Jayathilake, K; Lee, M; Meltzer, HY1
Dahl, ML; Engberg, G; Erhardt, S; Holtze, M; Linderholm, KR; Olsson, SK; Samuelsson, M; Skogh, E1
Condray, R; Dougherty, GG; Haas, GL; Kaddurah-Daouk, R; Keshavan, MS; Matson, WR; McEvoy, J; Montrose, DM; Reddy, RD; Yao, JK1
Müller, N; Myint, AM; Schwarz, MJ3
Kim, YK; Leonard, BE; Mueller, HH; Myint, AM; Scharpé, S; Schwarz, MJ; Steinbusch, HW; Verkerk, R; Zach, J1
Du Preez, JL; Harvey, BH; Möller, M1
Anderson, G; Maes, M1
Anderson, G; Berk, M; Maes, M1
Aymard, N; Caroli, F; Clement, MN; Gauillard, J; Jacquot, M; Vacheron, MN; Viala, A1
Kurup, AR; Kurup, PA1
CAFRUNY, EJ; DOMINO, EF1
AGARWAL, PS; BANERJEE, S1
BECKETT, PG; FROHMAN, CE; GOODMAN, M; LUBY, ED; SENF, R1
BERNSOHN, J; INSKIP, WM; LAUER, JW; ZELLER, EA1
KOPIN, IJ1
FLEISCHHACKER, HH; LANCASTER, JB; WHEELER, AP1
EDELSTEIN, EL; KRASSILOWSKY, D1
BROWN, RR; PETERS, HA; PRICE, JM1
CARDON, PV; KETY, SS; POLLIN, W1
BRENGELMANN, JC; PARE, CM; SANDLER, M1
BROWN, FC; KENNEDY, JK; WHITE, JB1
DIBNER, IM; FELDSTEIN, A; FREEMAN, H; HOAGLAND, H; HOPE, JM1
HEATH, RG1
GOOD, MH; YUWILER, A1
ALEXANDER, F; CROSLEY, AP; CURTIS, GC; SPRINCE, H1
ALEXANDER, F; JAMESON, D; PARKER, CM; SPRINCE, H1
BENASSI, P1
CHANG, LT; CHI, M1
LEE, SJ1
ALLEGRI, G; BENASSI, CA; BENASSI, P; RABASSINI, A1
FISCHL, J; RABIAH, S1
BERLET, HH; BULL, C; HIMWICH, HE; PSCHEIDT, GR; SPAIDE, J1
FELIX, WR; KOPIN, IJ; LABROSSE, EH; WESTLAKE, RJ1
BENASSI, CA; MUSAJO, L1
Faurbye, A; Pind, K1
BERLET, HH; BULL, C; HIMWICH, HE; KOHL, H; SPAIDE, J1
BERNIER, JJ; PAUPE, J1
ARONSON, H; BERTINO, J; GOODMAN, A; KLEE, GD1
LUCAS, J; RABINOVITCH, RD; SHAW, CR1
Bloch, Y; Fennig, S; Grauer, E; Levkovitz, Y; Ophir-Shaham, O; Treves, I1
Brahmachari, SK; Chauhan, C; Gandhi, C; Jain, S; Saleem, Q; Verma, R1
Sanders-Bush, E; Sodhi, MS1
Fekkes, D; Kahn, RS; Sijben, AE; Tuinier, S; van der Heijden, FM; Verhoeven, WM1
Crayton, JW; Hedeker, D; Hitsman, B; Pingitore, R; Spring, B; Wolf, W1
Bell, CJ; Hood, SD; Nutt, DJ1
Croft, RJ; Harrison, BJ; Leung, S; Nathan, PJ; O'Neill, BV; Phan, KL; Pipingas, A; Scholes, KE1
Kim, YK; Leonard, BE; Myint, AM; Park, SH; Scharpé, S; Steinbusch, HW; Verkerk, R1
Miüller, N; Schwarz, MJ1
Cwik, M; Llenos, IC; Miller, CL; Walkup, J; Weis, S1
Annable, L; Chouinard, G; Collu, R; Jones, BD1
Sedvall, G1
Arató, M; Banki, CM; Papp, Z1
Anderson, GM; Cohen, DJ; Fairbanks, L; Gerner, RH; Hare, TA; Linnoila, M; Scheinin, M; Shaywitz, BA; Young, JG1
Bender, DA3
McDonald, A1
Anderson, GM; Chouinard, G; Gauthier, S; Purdy, WC; Young, SN1
Cannon-Spoor, HE; DeLisi, LE; Neckers, LM; Potkin, SG; Wyatt, RJ1
Ervin, FR; Morand, C; Young, SN1
Hyyppä, M; Kampman, R; Latvala, M; Rimón, R1
Uebelhack, R1
Belendiuk, GW; Belendiuk, K; Crayton, JW; Freedman, DX1
Neumann, J; Sperschneider, H; Spustova, V; Stein, G1
Benyacoub, K; Bousquet, B; Cuche, H; Deniker, P; Dreux, C; Escande, C; Loo, H; Zarifian, E1
Breier, A1
Hemmings, GP; Ramchand, CN; Wei, J; Xu, H1
Bräunig, P; Gross, G; Halaris, A; Huber, G; Marler, M; Rao, ML; Strebel, B1
Bartko, JJ; Freedman, R; Gamache, PH; Gerhardt, GA; Issa, F; Kirch, DG; Lynch, M; Suddath, RL; Wyatt, RJ1
Bartko, JJ; Freedman, R; Gerhardt, GA; Issa, F; Kirch, DG; Suddath, RL; Wyatt, RJ1
Askenazy, F; Candito, M; Chambon, P; Darcourt, G; Myquel, M1
Azorin, JM; Dassa, D; Jeanningros, R; Serres, F1
Catalano, M; Lucca, A; Lucini, V; Smeraldi, E1
Davis, JM; Kamath, SK; Shapiro, LE; Sharma, RP; Soll, EA; Watanabe, MD1
Aymard, N; Baldacci, C; Caroli, F; Smagghe, PO; Vacheron, MN; Viala, A1
Arun, P; Deepadevi, KV; Kurup, PA; Manojkumar, V; Ravikumar, A1
Gallagher, P; Golightly, KL; Hobson, JE; Lloyd, JA; Mercer, G; Young, AH1
Degen, K; George, TP; McDougle, CJ; Potenza, MN; Sernyak, MJ; Woods, S1
Bartlett, JR; Bridges, PK; Curzon, G; Kantamaneni, BD1
Bousquet, B; Deniker, P; Dreux, C; Escande, C; Lôo, H; Zarifian, E1
Bousquet, B; Dreux, C; Escande, C1
Baker, HF; Cross, AJ; Crow, TJ; Glover, V; Joseph, MH; Killpack, WS; Lofthouse, R; Longden, A; Owen, F; Riley, GJ1
Guchhait, RB; Janson, C; Price, WH1
Stewart, BM1
Smythies, JR1
Fromen, Ch; Gottlib, D1
Demetriou, S; Domino, EF; Klinge, V; Tuttle, T1
Curzon, G; Kantamaneni, BD1
Baker, HF; Crow, TJ; Jospeh, MH; Riley, GJ; Risby, D1
Baumann, P; Gaillard, JM; Grasset, F; Laurian, S; Perey, M; Steck, A1
Baumann, P; Gaillard, JM; Grasset, F; Laurian, S; Steck, A1
Gaillard, JM; Tissot, R1
Boulu, R; Poitou, P1
Annable, L; Chouinard, Q; Sourkes, TL; Young, SN1
Anokhina, IP; Gamaleia, NB1
Chouinard, G; Jones, BD1
Faktor, MI; Mukhin, AG1
Bowers, MB; Heninger, GR1
Boleaga, B; Castellanos, G; Eisenring, JJ; Estrada, E; Gaillard, JM; Hovaguimian, T; Hyde, A; Miranda, R; Tissot, R1
Ax, AF; Frohman, CE; Gorham, JC; Novelly, RA1
Taylor, WM1
Chang, A; Neziroglu, F; Yaryura-Tobias, JA1
Mukhin, AG1
Dickerson, JW; Wiryanti, J1
Barthelemy, L; Degiovanni, A; Sizaret, P1
Tissot, R2
Gillin, JC; Kaplan, JA; Wyatt, RJ1
Lovett Doust, JW1
Cowen, MA3
Baumann, P; MGaillard, J1
Bartlett, JR; Bridges, PK; Curzon, G; Kantamaneni, BD; Sepping, P1
Gilka, L1
Doust, JW; Huszka, L; Zabek, DH1
Jakomow, B; Puzyński, S1
Bender, DA; Gruzelier, J; Hammond, N; Pigache, RM1
Banay-Schwartz, M; Deutsch, SI; Peace, TD; Rosse, RB; Schwartz, BL; Trinidad, AC; Zlotolow, S1
Ancill, RJ; Goumeniouk, AD; Koczapski, AB; MacEwan, GW1
Boni, RL; Heyes, MP; Markey, SP; Yergey, JA1
Davis, P; Dewey, DA; DiGiambattista, S; DiJohnson, C; Kramer, MS1
Nightingale, SL1
Goodman, SI; Kleinman, JE; Korpi, ER; Wyatt, RJ2
Alfredsson, G; Wiesel, FA1
Gerner, RH; Ninan, PT; van Kammen, DP1
Malek-Ahmadi, P1
Cowen, PJ; Kolakowska, T; Murdock, P1
Cowen, PJ; Gadhvi, H; Gosden, B; Kolakowska, T1
Gorynia, I; Uebelhack, R1
Abou-Saleh, MT; Coppen, A1
Kitzrow, W; Uebelhack, R1
Frohman, CE; Gottlieb, JS; Harmison, CR1
Arthur, RE; Frohman, CE; Gottlieb, JS; Harmison, CR1
Frohman, CE; Gottlieb, JS; Warner, KA1
Frohman, CE; Harmison, CR1
Arthur, RE; Frohman, CE; Gottlieb, JS; Yoon, HS1
Laplante, M; St-Laurent, J1
Arthur, RE; Caldwell, DF; Frohman, CE; Gottlieb, JS; Thomas, N; Zellers, R1
Ananth, JV; Ban, TA; Lehmann, HE1
Huszka, L; Lovett Doust, JW2
Beckett, PG; Frohman, CE; Gottlieb, JS1
Arthur, RE; Barry, CT; Frohman, CE; Warner, KA1
Bueno, J; Ginther, R; Himwich, HE; Spaide, J; Tanimukai, H1
Chiancone, FM1
Kanig, K; Oesterle, W1
Ottosson, JO; Rapp, W1
Kolpakov, VG1
Huttunen, MO1
Gottesman, II; Nicol, S; Seal, US1
Cerone, G; Feriozzi, F; Mancini, GM; Murri, L; Nurzia, A1
Bamji, AN; Bender, DA1
Filip, V; Haskovec, L; Hyánek, J; Krulík, R1
Doust, JW1
Bowers, MB2
Domino, EF; Krause, RR2
Caldwell, DF; Frohman, CE; Gottlieb, JS1
Stancer, HC1
Durkó, I; Huszák, I; Karsai, K1
Gilmour, DG; Manowitz, P; Racevskis, J1
Frosch, WA; Gilmour, DG; Manowitz, P; Shopsin, B1
Doust, JW; Huszka, L; Little, MH1
Caridroit, M; Duc-Aublet, F; Fontan, M; Miens, C; Testegute, T1
Payne, IR; Walsh, EM; Whittenburg, EJ1
Faurbye, A2
Szafranek, J; Szafranek, K1
Boulton, AA1
Ban, TA1
Bueno, JR; Ginther, R; Himwich, HE; Spaide, J; Tanimukai, H1
Himwich, HE; Neveln, L; Spaide, J; Tolentino, J1
Fujimori, M; Haskovec, L; Heller, B; Himwich, HE; Narasimhachari, N; Spaide, J; Tabushi, K1
Arushanian, EB; Stoliarov, GV; Tolpyshev, BA1
Szafranek, J1
Bueno, JR; Himwich, HE1
Gershon, ES; Shader, RI1
Berlet, HH; Bull, C; Himwich, HE; Matsumoto, K; Pscheidt, GR; Spaide, J1
Bennett, JL; Forrest, F; Hollister, LE; Moore, FF1

Reviews

34 review(s) available for tryptophan and Schizophrenia

ArticleYear
The tryptophan catabolite or kynurenine pathway in schizophrenia: meta-analysis reveals dissociations between central, serum, and plasma compartments.
    Molecular psychiatry, 2022, Volume: 27, Issue:9

    Topics: Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenic Acid; Kynurenine; Quinolinic Acid; Schizophrenia; Tryptophan

2022
Blood-based kynurenine pathway alterations in schizophrenia spectrum disorders: A meta-analysis.
    Schizophrenia research, 2020, Volume: 223

    Topics: Aged; Humans; Kynurenic Acid; Kynurenine; Quinolinic Acid; Schizophrenia; Tryptophan

2020
Dysregulation of kynurenine pathway and potential dynamic changes of kynurenine in schizophrenia: A systematic review and meta-analysis.
    Neuroscience and biobehavioral reviews, 2021, Volume: 123

    Topics: Humans; Kynurenic Acid; Kynurenine; Quinolinic Acid; Schizophrenia; Tryptophan

2021
Meta-analysis of Cerebrospinal Fluid Cytokine and Tryptophan Catabolite Alterations in Psychiatric Patients: Comparisons Between Schizophrenia, Bipolar Disorder, and Depression.
    Schizophrenia bulletin, 2018, 01-13, Volume: 44, Issue:1

    Topics: Bipolar Disorder; Cytokines; Depressive Disorder, Major; Humans; Inflammation; Schizophrenia; Tryptophan

2018
Metabolomics in patients with psychosis: A systematic review.
    American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, 2018, Volume: 177, Issue:6

    Topics: 3-Hydroxybutyric Acid; Aspartic Acid; Biomarkers; Bipolar Disorder; Creatine; Female; Glutamic Acid; Glutathione; Humans; Kynurenine; Lactic Acid; Linoleic Acid; Male; Metabolome; Metabolomics; Psychotic Disorders; Schizophrenia; Serine; Tryptophan

2018
Linking phencyclidine intoxication to the tryptophan-kynurenine pathway: Therapeutic implications for schizophrenia.
    Neurochemistry international, 2019, Volume: 125

    Topics: Animals; Brain; Humans; Kynurenine; Phencyclidine; Schizophrenia; Signal Transduction; Tryptophan

2019
Neuropsychiatric disease and Toxoplasma gondii infection.
    Neuroimmunomodulation, 2009, Volume: 16, Issue:2

    Topics: Animals; Behavior; Behavior, Animal; Cats; Cytokines; Depression; Dopamine; Female; Host-Parasite Interactions; Humans; Male; Mental Disorders; Mice; Nervous System Diseases; Neurons; Neurosecretory Systems; Protozoan Proteins; Rats; Risk Factors; Schizophrenia; Serotonin; Toxoplasma; Toxoplasmosis; Toxoplasmosis, Animal; Tryptophan

2009
New promises for manipulation of kynurenine pathway in cancer and neurological diseases.
    Expert opinion on therapeutic targets, 2009, Volume: 13, Issue:2

    Topics: Animals; Drug Delivery Systems; Drug Discovery; Humans; Huntington Disease; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Neoplasms; Schizophrenia; Tryptophan

2009
Kynurenine pathway in schizophrenia: pathophysiological and therapeutic aspects.
    Current pharmaceutical design, 2011, Volume: 17, Issue:2

    Topics: Animals; Anti-Inflammatory Agents; Antipsychotic Agents; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inflammation; Kynurenic Acid; Kynurenine; Mice; Molecular Targeted Therapy; Rats; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Synaptic Transmission; Tryptophan

2011
Immunological treatment options for schizophrenia.
    Current pharmaceutical biotechnology, 2012, Volume: 13, Issue:8

    Topics: Animals; Antipsychotic Agents; Astrocytes; Cyclooxygenase 2 Inhibitors; Humans; Kynurenine; Microglia; Schizophrenia; Tryptophan

2012
Schizophrenia: linking prenatal infection to cytokines, the tryptophan catabolite (TRYCAT) pathway, NMDA receptor hypofunction, neurodevelopment and neuroprogression.
    Progress in neuro-psychopharmacology & biological psychiatry, 2013, Apr-05, Volume: 42

    Topics: Animals; Brain; Cytokines; Disease Progression; Female; Humans; Infections; Pregnancy; Prenatal Exposure Delayed Effects; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Tryptophan

2013
Inflammation in schizophrenia.
    Advances in protein chemistry and structural biology, 2012, Volume: 88

    Topics: Antipsychotic Agents; Brain; Humans; Inflammation; Kynurenine; Macrophages; Microglia; Monocytes; Schizophrenia; Tryptophan

2012
Schizophrenia is primed for an increased expression of depression through activation of immuno-inflammatory, oxidative and nitrosative stress, and tryptophan catabolite pathways.
    Progress in neuro-psychopharmacology & biological psychiatry, 2013, Apr-05, Volume: 42

    Topics: Animals; Comorbidity; Depressive Disorder; Humans; Inflammation; Nitrosation; Oxidative Stress; Schizophrenia; Signal Transduction; Tryptophan

2013
ASPECTS OF DISORDERS OF THE KYNURENINE PATHWAY OF TRYPTOPHAN METABOLISM IN MAN.
    Advances in clinical chemistry, 1964, Volume: 7

    Topics: Amino Acids; Diabetes Mellitus; Fluids and Secretions; Geriatrics; Hodgkin Disease; Humans; Kidney Calculi; Kynurenine; Leukemia; Liver Diseases; Lymphoma; Metabolic Diseases; Pregnancy; Schizophrenia; Seizures; Tryptophan; Urine; Urologic Diseases; Vitamin B 6 Deficiency; Xanthurenates

1964
Serotonin and brain development.
    International review of neurobiology, 2004, Volume: 59

    Topics: Animals; Anxiety; Autistic Disorder; Brain; Brain Chemistry; Down Syndrome; Humans; Learning; Models, Animal; Mood Disorders; Neuronal Plasticity; Receptors, Serotonin; Schizophrenia; Serotonin; Stress, Physiological; Synapses; Tryptophan

2004
Acute tryptophan depletion. Part II: clinical effects and implications.
    The Australian and New Zealand journal of psychiatry, 2005, Volume: 39, Issue:7

    Topics: Alleles; Alzheimer Disease; Autistic Disorder; Bipolar Disorder; Cognitive Behavioral Therapy; Depressive Disorder, Major; Disruptive, Impulse Control, and Conduct Disorders; Feeding and Eating Disorders; Female; Humans; Hydroxyindoleacetic Acid; Monoamine Oxidase Inhibitors; Premenstrual Syndrome; Promoter Regions, Genetic; Schizophrenia; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins; Sleep Wake Disorders; Sleep, REM; Surveys and Questionnaires; Tryptophan

2005
The immunological basis of glutamatergic disturbance in schizophrenia: towards an integrated view.
    Journal of neural transmission. Supplementum, 2007, Issue:72

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Astrocytes; Brain; Carrier Proteins; Cyclooxygenase 2 Inhibitors; Cytokines; Dinoprostone; Dopamine; Dysbindin; Dystrophin-Associated Proteins; Glutamine; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenic Acid; Neuregulins; Psychoneuroimmunology; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Schizophrenic Psychology; Tryptophan; Tryptophan Oxygenase

2007
Biochemistry of tryptophan in health and disease.
    Molecular aspects of medicine, 1983, Volume: 6, Issue:2

    Topics: Animals; Appetite Regulation; Brain Chemistry; Depressive Disorder; Female; Hartnup Disease; Humans; Male; Malignant Carcinoid Syndrome; Pellagra; Pineal Gland; Rats; Schizophrenia; Serotonin; Sleep; Tryptophan; Tryptophan Hydroxylase; Tryptophan Oxygenase; Urinary Bladder Neoplasms

1983
Mushrooms and madness. Hallucinogenic mushrooms and some psychopharmacological implications.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1980, Volume: 25, Issue:7

    Topics: Amanita; Basidiomycota; Chemistry; Guatemala; Hallucinogens; History, Medieval; History, Modern 1601-; Humans; India; Mexico; Monoamine Oxidase; N,N-Dimethyltryptamine; Phenylalanine; Schizophrenia; Siberia; Tryptophan

1980
Serotonin, schizophrenia and antipsychotic drug action.
    Schizophrenia research, 1995, Volume: 14, Issue:3

    Topics: Antipsychotic Agents; Basal Ganglia Diseases; Clozapine; Humans; Isoxazoles; Piperazines; Piperidines; Risperidone; Schizophrenia; Serotonin; Tryptophan

1995
[Current biochemical conceptions of mental disorders. I. Biogenic amines in the pathogenesis of schizophrenia].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1979, Volume: 79, Issue:8

    Topics: Animals; Biogenic Amines; Blood Platelets; Brain Chemistry; Catechol O-Methyltransferase; Disease Models, Animal; Dopamine; Dopamine beta-Hydroxylase; Ethylene Glycols; Growth Hormone; Hallucinogens; Homovanillic Acid; Humans; Hydroxydopamines; Monoamine Oxidase; Norepinephrine; Psychoses, Substance-Induced; Receptors, Dopamine; Schizophrenia; Serotonin; Tryptophan; Vanilmandelic Acid

1979
The common pathophysiology of monaminergic psychoses: a new hypothesis.
    Neuropsychobiology, 1975, Volume: 1, Issue:4

    Topics: 5-Hydroxytryptophan; Amino Acids; Biological Transport, Active; Bipolar Disorder; Blood-Brain Barrier; Brain; Catecholamines; Clomipramine; Dihydroxyphenylalanine; Dopamine; Electroconvulsive Therapy; Humans; Lithium; Lysergic Acid Diethylamide; Models, Biological; Monoamine Oxidase Inhibitors; Psychotic Disorders; Schizophrenia; Serotonin; Tranquilizing Agents; Tryptophan; Tyrosine

1975
Disturbances in tryptophan and serotonin metabolism in affective psychoses and schizophrenia.
    Polish journal of pharmacology and pharmacy, 1975, Volume: 27, Issue:Suppl

    Topics: Affective Symptoms; Depression; Humans; Psychotic Disorders; Schizophrenia; Serotonin; Tryptophan

1975
Mass spectrometric determinations of tryptophan and its metabolites.
    Advances in experimental medicine and biology, 1991, Volume: 294

    Topics: Animals; Body Fluids; Gas Chromatography-Mass Spectrometry; Humans; Mass Spectrometry; Melatonin; Molecular Structure; Nervous System Diseases; Pineal Gland; Quinolinic Acid; Quinolinic Acids; Schizophrenia; Serotonin; Tryptophan

1991
The biology of folate in depression: implications for nutritional hypotheses of the psychoses.
    Journal of psychiatric research, 1986, Volume: 20, Issue:2

    Topics: Anorexia Nervosa; Biogenic Amines; Brain; Depressive Disorder; Diet; Folic Acid; Folic Acid Deficiency; Homocystinuria; Humans; Models, Theoretical; Pellagra; Pterins; S-Adenosylmethionine; Schizophrenia; Tryptophan; Vitamin B 12 Deficiency

1986
[Research into the biochemical bases of schizophrenic syndromes: a review].
    L'union medicale du Canada, 1973, Volume: 102, Issue:11

    Topics: Alpha-Globulins; Amphetamine; Ceruloplasmin; Energy Metabolism; Fenclonine; gamma-Globulins; Hallucinogens; Humans; Hydroxydopamines; Models, Theoretical; Porphyrins; Schizophrenia; Synaptic Transmission; Tryptophan; Tyrosine

1973
[Biochemical treatment possibilities in psychoses].
    Die Medizinische Welt, 1969, Sep-06, Volume: 36

    Topics: Amino Acids; Ascorbic Acid; Dihydroxyphenylalanine; Humans; Methionine; Niacinamide; Nicotinic Acids; Phenylalanine; Psychotic Disorders; Pyridoxine; Schizophrenia; Tryptophan; Tyrosine

1969
[Inadequacy of the monoamine oxidase system--the probable pathogenetic factor in schizophrenia (review)].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1974, Volume: 74, Issue:8

    Topics: Adenosine Triphosphatases; Adrenochrome; Amines; Animals; Brain Chemistry; Dimethoxyphenylethylamine; Dopamine; Epinephrine; Ethanolamines; Humans; Hydroxydopamines; Metabolic Diseases; Methionine; Mice; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Norepinephrine; Oxidation-Reduction; Phenylalanine; Rats; Reserpine; Schizophrenia; Tryptamines; Tryptophan

1974
[The biochemistry of mental disorders].
    Duodecim; laaketieteellinen aikakauskirja, 1970, Volume: 86, Issue:24

    Topics: Bipolar Disorder; Catecholamines; Humans; Indoles; Monoamine Oxidase Inhibitors; Receptors, Neurotransmitter; Schizophrenia; Tryptophan

1970
Psychopharmacology. Yesterday, today and tomorrow: a point of view.
    Canadian Psychiatric Association journal, 1973, Volume: 18, Issue:5

    Topics: Affective Symptoms; Amitriptyline; Antidepressive Agents; Canada; Carbonates; Depression; Dihydroxyphenylalanine; Drug Industry; Electroconvulsive Therapy; Humans; Imipramine; Lithium; Mental Disorders; Methoxyhydroxyphenylglycol; Monoamine Oxidase Inhibitors; Nicotinic Acids; Psychopharmacology; Research Support as Topic; Schizophrenia; Tranquilizing Agents; Tryptophan; Vitamins

1973
The role of amines in the etiology of schizophrenia.
    Comprehensive psychiatry, 1968, Volume: 9, Issue:2

    Topics: Adrenochrome; Amines; Amphetamine; Brain Chemistry; Dopamine; Epinephrine; Humans; Indoles; Kynurenine; Mescaline; Monoamine Oxidase Inhibitors; Norepinephrine; Phenethylamines; Phenylalanine; Psychoses, Substance-Induced; Schizophrenia; Serotonin; Tryptamines; Tryptophan

1968
[Tryptophan and its metabolism in schizophrenia].
    Psychiatria polska, 1970, Volume: 4, Issue:5

    Topics: Chlorpromazine; Drug Synergism; Haloperidol; Humans; Monoamine Oxidase Inhibitors; Neurologic Manifestations; Nicotinic Acids; Schizophrenia; Serotonin; Tryptophan; Xanthurenates

1970
Biochemical research in schizophrenia.
    Nature, 1971, May-07, Volume: 231, Issue:5297

    Topics: Brain; Chromatography, Paper; Hallucinogens; Humans; Methionine; Methylation; Motor Activity; Phenethylamines; Phenylalanine; Schizophrenia; Tryptamines; Tryptophan

1971
Drug treatment in schizophrenia.
    Canadian Psychiatric Association journal, 1971, Volume: 16, Issue:6

    Topics: Butyrophenones; Chlorpromazine; Evaluation Studies as Topic; Humans; Phenothiazines; Phenylalanine; Reserpine; Schizophrenia; Thiothixene; Tranquilizing Agents; Tryptophan; Xanthenes

1971

Trials

22 trial(s) available for tryptophan and Schizophrenia

ArticleYear
Tryptophan challenge in individuals with schizophrenia and healthy controls: acute effects on circulating kynurenine and kynurenic acid, cognition and cerebral blood flow.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2023, Volume: 48, Issue:11

    Topics: Animals; Cerebrovascular Circulation; Cognition; Cross-Over Studies; Humans; Kynurenic Acid; Kynurenine; Rats; Rats, Wistar; Schizophrenia; Tryptophan

2023
Cytokine changes and tryptophan metabolites in medication-naïve and medication-free schizophrenic patients.
    Neuropsychobiology, 2009, Volume: 59, Issue:2

    Topics: Adult; Antipsychotic Agents; Cytokines; Female; Humans; Kynurenine; Male; Schizophrenia; Time Factors; Tryptophan

2009
3-Hydroxykynurenine and clinical symptoms in first-episode neuroleptic-naive patients with schizophrenia.
    The international journal of neuropsychopharmacology, 2011, Volume: 14, Issue:6

    Topics: Adolescent; Adult; Antipsychotic Agents; Brief Psychiatric Rating Scale; Chromatography, High Pressure Liquid; Diagnostic and Statistical Manual of Mental Disorders; Humans; Kynurenine; Monte Carlo Method; Neuropsychological Tests; Psychotic Disorders; Schizophrenia; Tryptophan; Young Adult

2011
Effect of L-tryptophan on memory in patients with schizophrenia.
    The Journal of nervous and mental disease, 2003, Volume: 191, Issue:9

    Topics: Adult; Antipsychotic Agents; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Memory; Memory Disorders; Neuropsychological Tests; Psychiatric Status Rating Scales; Schizophrenia; Schizophrenic Psychology; Tryptophan

2003
Acute serotonin and dopamine depletion improves attentional control: findings from the stroop task.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2007, Volume: 32, Issue:7

    Topics: Adult; Attention; Biogenic Monoamines; Brain; Brain Chemistry; Dopamine; Double-Blind Method; Humans; Male; Mood Disorders; Neural Pathways; Neuropsychological Tests; Placebos; Schizophrenia; Serotonin; Synaptic Transmission; Tryptophan; Tyrosine

2007
Lack of tolerance to long-term neuroleptic treatment in dopamine tuberoinfundibular system.
    Acta psychiatrica Scandinavica, 1981, Volume: 64, Issue:5

    Topics: Adult; Aged; Antipsychotic Agents; Benserazide; Chlorpromazine; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Middle Aged; Prolactin; Receptors, Dopamine; Schizophrenia; Time Factors; Tryptophan

1981
A multidimensional approach to analysis of cerebrospinal fluid biogenic amines in schizophrenia: I. Comparisons with healthy control subjects and neuroleptic-treated/unmedicated pairs analyses.
    Psychiatry research, 1994, Volume: 52, Issue:3

    Topics: Adult; Biogenic Amines; Chromatography, High Pressure Liquid; Chronic Disease; Dopamine; Double-Blind Method; Female; Haloperidol; Humans; Kynurenine; Male; Norepinephrine; Schizophrenia; Schizophrenic Psychology; Serotonin; Tryptophan; Tyrosine

1994
A multidimensional approach to analysis of cerebrospinal fluid biogenic amines in schizophrenia: II. Correlations with psychopathology.
    Psychiatry research, 1994, Volume: 52, Issue:3

    Topics: Adult; Biogenic Amines; Dopamine; Double-Blind Method; Female; Haloperidol; Humans; Kynurenine; Male; Norepinephrine; Psychiatric Status Rating Scales; Schizophrenia; Schizophrenic Psychology; Serotonin; Tryptophan; Tyrosine

1994
Neutral amino acid availability in two major psychiatric disorders.
    Progress in neuro-psychopharmacology & biological psychiatry, 1995, Volume: 19, Issue:4

    Topics: Adolescent; Adult; Aged; Amino Acids; Depressive Disorder; Diet; Female; Humans; Male; Middle Aged; Schizophrenia; Tryptophan

1995
Acute dietary tryptophan depletion: effects on schizophrenic positive and negative symptoms.
    Neuropsychobiology, 1997, Volume: 35, Issue:1

    Topics: Adult; Brain; Cross-Over Studies; Delusions; Depression; Double-Blind Method; Female; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Psychotic Disorders; Schizophrenia; Schizophrenic Psychology; Serotonin; Tryptophan

1997
Pharmacoclinical strategy in neuroleptic resistant schizophrenic patients treated by clozapine: clinical evolution, concentration of plasma and red blood cell clozapine and desmethylclozapine, whole blood serotonin and tryptophan.
    Progress in neuro-psychopharmacology & biological psychiatry, 1999, Volume: 23, Issue:1

    Topics: Adult; Antidepressive Agents, Second-Generation; Antipsychotic Agents; Brief Psychiatric Rating Scale; Clozapine; Depressive Disorder; Drug Monitoring; Female; Fluoxetine; Humans; Male; Middle Aged; Schizophrenia; Serotonin; Tryptophan

1999
Acute tryptophan depletion in schizophrenia.
    Psychological medicine, 2001, Volume: 31, Issue:1

    Topics: Administration, Oral; Adult; Affect; Amino Acids; Blood-Brain Barrier; Cognition; Cross-Over Studies; Double-Blind Method; Female; Humans; Male; Middle Aged; Protein Biosynthesis; Schizophrenia; Severity of Illness Index; Treatment Outcome; Tryptophan

2001
Acute tryptophan depletion in schizophrenic patients treated with clozapine.
    Archives of general psychiatry, 2002, Volume: 59, Issue:3

    Topics: Adult; Brain; Clozapine; Double-Blind Method; Female; Humans; Male; Middle Aged; Psychiatric Status Rating Scales; Schizophrenia; Schizophrenic Psychology; Serotonin; Tryptophan

2002
A controlled study of tryptophan-benserazide in schizophrenia.
    Communications in psychopharmacology, 1978, Volume: 2, Issue:1

    Topics: Adult; Aged; Benserazide; Chlorpromazine; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrazines; Kynurenine; Male; Middle Aged; Psychiatric Status Rating Scales; Schizophrenia; Tryptophan

1978
Evidence of brain dopamine deficiency in schizophrenia.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1979, Volume: 24, Issue:7

    Topics: Benserazide; Brain; Chlorpromazine; Dopamine; Double-Blind Method; Drug Therapy, Combination; Humans; Methyldopa; Receptors, Dopamine; Rubidium; Schizophrenia; Serotonin; Tryptophan

1979
Clinical effects of tryptophan in chronic schizophrenic patients.
    Biological psychiatry, 1976, Volume: 11, Issue:5

    Topics: Adult; Chronic Disease; Clinical Trials as Topic; Drug Evaluation; Humans; Male; Placebos; Pyridoxine; Schizophrenia; Tryptophan

1976
Effect of a low-tryptophan diet as an adjuvant to conventional neuroleptic therapy in schizophrenia.
    Clinical neuropharmacology, 1992, Volume: 15, Issue:2

    Topics: Adjuvants, Pharmaceutic; Adult; Affect; Antipsychotic Agents; Behavior; Combined Modality Therapy; Humans; Irritable Mood; Male; Middle Aged; Psychiatric Status Rating Scales; Schizophrenia; Schizophrenic Psychology; Time Factors; Tryptophan

1992
Monoamine metabolites and amino acids in serum from schizophrenic patients before and during sulpiride treatment.
    Psychopharmacology, 1989, Volume: 99, Issue:3

    Topics: Adolescent; Adult; Amino Acids; Biogenic Monoamines; Female; Glutamates; Glutamine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Meglutol; Schizophrenia; Sulpiride; Tryptophan; Tyrosine

1989
Potentiation of therapeutic effects of nicotinic acid by pyridoxine in chronic schizophrenics.
    Canadian Psychiatric Association journal, 1973, Volume: 18, Issue:5

    Topics: Adult; Aminobutyrates; Antipsychotic Agents; Canada; Clinical Trials as Topic; Drug Synergism; Female; Hospitals, Psychiatric; Humans; Length of Stay; Male; Methionine; Middle Aged; Nicotinic Acids; Phenothiazines; Placebos; Psychiatric Status Rating Scales; Pyridoxine; Schizophrenia; Tryptophan

1973
Influence of some psychoactive drugs on mineral metabolism in man.
    International pharmacopsychiatry, 1973, Volume: 8, Issue:3

    Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Adult; Analysis of Variance; Antipsychotic Agents; Benztropine; Body Weight; Butyrophenones; Calcium; Female; Glycine; Humans; Magnesium; Middle Aged; Phenelzine; Phenothiazines; Placebos; Potassium; Psychiatric Status Rating Scales; Schizophrenia; Sodium; Tryptophan

1973
Free and bound serum tryptophan in drug-free normal controls and chronic schizophrenic patients.
    Biological psychiatry, 1974, Volume: 8, Issue:3

    Topics: Adult; Chronic Disease; Clinical Trials as Topic; Drug Tolerance; Fasting; Fluorometry; Humans; Male; Middle Aged; Protein Binding; Schizophrenia; Time Factors; Tryptophan

1974
Metabolic control of body temperature in man.
    International pharmacopsychiatry, 1973, Volume: 8, Issue:4

    Topics: Adult; Body Temperature Regulation; Circadian Rhythm; Female; Humans; Middle Aged; Norepinephrine; Phenelzine; Placebos; Schizophrenia; Serotonin; Time Factors; Tryptophan

1973

Other Studies

176 other study(ies) available for tryptophan and Schizophrenia

ArticleYear
The immune-kynurenine pathway in social anxiety disorder.
    Brain, behavior, and immunity, 2022, Volume: 99

    Topics: Female; Humans; Kynurenic Acid; Kynurenine; Male; Phobia, Social; Schizophrenia; Tryptophan

2022
Major neurocognitive psychosis: a novel schizophrenia endophenotype class that is based on machine learning and resembles Kraepelin's and Bleuler's conceptions.
    Acta neuropsychiatrica, 2023, Volume: 35, Issue:3

    Topics: Endophenotypes; Humans; Machine Learning; Psychotic Disorders; Schizophrenia; Tryptophan

2023
A Preliminary Comparison of Plasma Tryptophan Metabolites and Medium- and Long-Chain Fatty Acids in Adult Patients with Major Depressive Disorder and Schizophrenia.
    Medicina (Kaunas, Lithuania), 2023, Feb-20, Volume: 59, Issue:2

    Topics: Adult; Depressive Disorder, Major; Fatty Acids; Fatty Acids, Omega-3; Humans; Reproducibility of Results; Schizophrenia; Tryptophan

2023
The association between inflammation and kynurenine pathway metabolites in electroconvulsive therapy for schizophrenia: Implications for clinical efficacy.
    Brain, behavior, and immunity, 2023, Volume: 113

    Topics: Electroconvulsive Therapy; Humans; Interleukin-18; Kynurenic Acid; Kynurenine; RNA, Messenger; Schizophrenia; Treatment Outcome; Tryptophan

2023
Transplantation of microbiota from drug-free patients with schizophrenia causes schizophrenia-like abnormal behaviors and dysregulated kynurenine metabolism in mice.
    Molecular psychiatry, 2020, Volume: 25, Issue:11

    Topics: Animals; Case-Control Studies; Dopamine; Fecal Microbiota Transplantation; Gastrointestinal Microbiome; Humans; Kynurenic Acid; Kynurenine; Male; Mice; Schizophrenia; Schizophrenic Psychology; Serotonin; Tryptophan

2020
Schizophrenia phenomenology comprises a bifactorial general severity and a single-group factor, which are differently associated with neurotoxic immune and immune-regulatory pathways.
    Biomolecular concepts, 2019, Nov-17, Volume: 10, Issue:1

    Topics: Adult; Biomarkers; Female; Humans; Immunoglobulin A; Immunoglobulin M; Male; Neurotoxins; Schizophrenia; Severity of Illness Index; Tryptophan

2019
Preliminary comparative analysis of kynurenine pathway metabolites in chronic ketamine users, schizophrenic patients, and healthy controls.
    Human psychopharmacology, 2020, Volume: 35, Issue:4

    Topics: Adult; Case-Control Studies; Chromatography, High Pressure Liquid; Female; Humans; Ketamine; Kynurenic Acid; Kynurenine; Male; Middle Aged; Psychiatric Status Rating Scales; Schizophrenia; Substance-Related Disorders; Tandem Mass Spectrometry; Time Factors; Tryptophan; Young Adult

2020
Effects of neuroactive metabolites of the tryptophan pathway on working memory and cortical thickness in schizophrenia.
    Translational psychiatry, 2021, 04-01, Volume: 11, Issue:1

    Topics: Humans; Kynurenic Acid; Kynurenine; Memory, Short-Term; Quinolinic Acid; Schizophrenia; Tryptophan

2021
Quinolinic acid is associated with cognitive deficits in schizophrenia but not major depressive disorder.
    Scientific reports, 2021, 05-11, Volume: 11, Issue:1

    Topics: Adult; Case-Control Studies; Cognition; Cognitive Dysfunction; Depressive Disorder, Major; Female; Humans; Kynurenine; Male; Middle Aged; Quinolinic Acid; Schizophrenia; Tryptophan; Young Adult

2021
The kynurenine pathway in schizophrenia and other mental disorders: Insight from meta-analyses on the peripheral blood levels of tryptophan and related metabolites.
    Schizophrenia research, 2021, Volume: 232

    Topics: Bipolar Disorder; Humans; Kynurenic Acid; Kynurenine; Schizophrenia; Tryptophan

2021
Depressive, anxiety and hypomanic symptoms in schizophrenia may be driven by tryptophan catabolite (TRYCAT) patterning of IgA and IgM responses directed to TRYCATs.
    Progress in neuro-psychopharmacology & biological psychiatry, 2018, Jan-03, Volume: 80, Issue:Pt C

    Topics: Adolescent; Adult; Aged; Anxiety Disorders; Case-Control Studies; Cyclothymic Disorder; Depression; Female; Humans; Immunoglobulin A; Immunoglobulin M; Male; Middle Aged; Schizophrenia; Signal Transduction; Tryptophan; Young Adult

2018
Changes in Tryptophan Catabolite (TRYCAT) Pathway Patterning Are Associated with Mild Impairments in Declarative Memory in Schizophrenia and Deficits in Semantic and Episodic Memory Coupled with Increased False-Memory Creation in Deficit Schizophrenia.
    Molecular neurobiology, 2018, Volume: 55, Issue:6

    Topics: Adult; Case-Control Studies; Female; Humans; Linear Models; Male; Memory Disorders; Memory, Episodic; Multivariate Analysis; Neuropsychological Tests; Schizophrenia; Semantics; Tryptophan

2018
Kynurenine is correlated with IL-1β in plasma of schizophrenia patients.
    Journal of neural transmission (Vienna, Austria : 1996), 2018, Volume: 125, Issue:5

    Topics: Adult; Female; Humans; Interleukin-1beta; Kynurenine; Male; Schizophrenia; Tryptophan

2018
Towards a new classification of stable phase schizophrenia into major and simple neuro-cognitive psychosis: Results of unsupervised machine learning analysis.
    Journal of evaluation in clinical practice, 2018, Volume: 24, Issue:4

    Topics: Adult; Behavioral Symptoms; Cognitive Reserve; Cytokines; Female; Humans; Inflammation; Male; Middle Aged; Neurocognitive Disorders; Neuroimmunomodulation; Patient Acuity; Psychiatric Status Rating Scales; Psychotic Disorders; Quality of Life; Schizophrenia; Schizophrenic Psychology; Tryptophan; Unsupervised Machine Learning

2018
The Effects of Tryptophan Catabolites on Negative Symptoms and Deficit Schizophrenia are Partly Mediated by Executive Impairments: Results of Partial Least Squares Path Modeling.
    CNS & neurological disorders drug targets, 2018, Volume: 17, Issue:6

    Topics: Adolescent; Adult; Aged; Analysis of Variance; Cognition Disorders; Executive Function; Female; Humans; Immunoglobulin A; Immunoglobulin M; Kynurenic Acid; Kynurenine; Kynurenine 3-Monooxygenase; Male; Middle Aged; Neuropsychological Tests; Picolinic Acids; Psychiatric Status Rating Scales; Quinolinic Acid; Schizophrenia; Schizophrenic Psychology; Tryptophan; Xanthurenates; Young Adult

2018
A New Schizophrenia Model: Immune Activation is Associated with the Induction of Different Neurotoxic Products which Together Determine Memory Impairments and Schizophrenia Symptom Dimensions.
    CNS & neurological disorders drug targets, 2019, Volume: 18, Issue:2

    Topics: Anxiety; Anxiety Disorders; Humans; Memory Disorders; Neuropsychological Tests; Schizophrenia; Tryptophan; Xanthurenates

2019
Supervised machine learning to decipher the complex associations between neuro-immune biomarkers and quality of life in schizophrenia.
    Metabolic brain disease, 2019, Volume: 34, Issue:1

    Topics: Adolescent; Adult; Aged; Anxiety; Biomarkers; Case-Control Studies; Depression; Female; Humans; Male; Middle Aged; Neuropsychological Tests; Quality of Life; Schizophrenia; Schizophrenic Psychology; Supervised Machine Learning; Tryptophan; Young Adult

2019
Serum xanthurenic acid levels: Reduced in subjects at ultra high risk for psychosis.
    Schizophrenia research, 2019, Volume: 208

    Topics: Adolescent; Adult; Disease Progression; Female; Humans; Hydroxyindoleacetic Acid; Kynurenic Acid; Kynurenine; Male; ortho-Aminobenzoates; Prodromal Symptoms; Psychotic Disorders; Quinolinic Acid; Risk; Schizophrenia; Tryptophan; Xanthurenates; Young Adult

2019
Metabolic dysfunctions in the kynurenine pathway, noradrenergic and purine metabolism in schizophrenia and bipolar disorders.
    Psychological medicine, 2020, Volume: 50, Issue:4

    Topics: Adolescent; Adult; Bipolar Disorder; Female; Humans; Kynurenine; Male; Metabolic Networks and Pathways; Metabolomics; Middle Aged; Psychotic Disorders; Schizophrenia; Tryptophan; Tyrosine; Young Adult

2020
Twin study shows association between monocyte chemoattractant protein-1 and kynurenic acid in cerebrospinal fluid.
    European archives of psychiatry and clinical neuroscience, 2020, Volume: 270, Issue:7

    Topics: Adult; Aged; Bipolar Disorder; Chemokine CCL2; Cohort Studies; Female; Humans; Kynurenic Acid; Male; Middle Aged; Quinolinic Acid; Schizophrenia; Sweden; Tryptophan

2020
How and why Toxoplasma makes us crazy.
    Trends in parasitology, 2013, Volume: 29, Issue:4

    Topics: Accidents, Occupational; Accidents, Traffic; Animals; Behavior; Brain; Cats; Dopamine; Female; Humans; Male; Mice; Pregnancy; Risk Factors; Schizophrenia; Sexually Transmitted Diseases; Suicide; Testosterone; Toxoplasma; Toxoplasmosis; Tryptophan

2013
Decreased L-tryptophan concentration in distinctive brain regions of mice treated repeatedly with phencyclidine.
    Analytical and bioanalytical chemistry, 2013, Volume: 405, Issue:25

    Topics: Animals; Brain; Chromatography, High Pressure Liquid; Excitatory Amino Acid Antagonists; Isothiocyanates; Male; Mice; Oxadiazoles; Phencyclidine; Schizophrenia; Tryptophan

2013
Impact of different antipsychotics on cytokines and tryptophan metabolites in stimulated cultures from patients with schizophrenia.
    Psychiatria Danubina, 2013, Volume: 25, Issue:4

    Topics: Antipsychotic Agents; Cell Culture Techniques; Cytokines; Female; Humans; Male; Psychiatric Status Rating Scales; Schizophrenia; Tryptophan

2013
Effect of maternal immune activation on the kynurenine pathway in preadolescent rat offspring and on MK801-induced hyperlocomotion in adulthood: amelioration by COX-2 inhibition.
    Brain, behavior, and immunity, 2014, Volume: 41

    Topics: Animals; Brain; Celecoxib; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; Dizocilpine Maleate; Female; Gestational Age; Hyperkinesis; Kynurenic Acid; Kynurenine; Male; Picolinic Acids; Poly I-C; Pregnancy; Prenatal Exposure Delayed Effects; Pyrazoles; Quinolinic Acid; Random Allocation; Rats; Rats, Wistar; Schizophrenia; Sexual Maturation; Sulfonamides; Tryptophan

2014
[A study of IL-1Β and IDO gene polymorphisms in patients with schizophrenia].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2014, Volume: 114, Issue:5

    Topics: Adult; Alleles; Female; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interleukin-1beta; Kynurenine; Male; Metabolic Networks and Pathways; Minisatellite Repeats; Polymorphism, Genetic; Schizophrenia; Tryptophan; Young Adult

2014
Increased levels of IL-6 in the cerebrospinal fluid of patients with chronic schizophrenia--significance for activation of the kynurenine pathway.
    Journal of psychiatry & neuroscience : JPN, 2015, Volume: 40, Issue:2

    Topics: Adult; Astrocytes; Cells, Cultured; Cerebral Cortex; Chronic Disease; Female; Humans; Interleukin-6; Interleukin-8; Kynurenic Acid; Kynurenine; Male; Middle Aged; Schizophrenia; Tryptophan; Young Adult

2015
Multiprobe molecular imaging of an NMDA receptor hypofunction rat model for glutamatergic dysfunction.
    Psychiatry research. Neuroimaging, 2016, Feb-28, Volume: 248

    Topics: Animals; Brain; Disease Models, Animal; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; Kynurenine; Male; Molecular Imaging; Positron-Emission Tomography; Rats; Rats, Sprague-Dawley; Receptor, Metabotropic Glutamate 5; Receptors, N-Methyl-D-Aspartate; Schizophrenia; Tryptophan

2016
Tryptophan Metabolism and White Matter Integrity in Schizophrenia.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2016, Volume: 41, Issue:10

    Topics: Adult; Analysis of Variance; Anisotropy; Diffusion Tensor Imaging; Female; Glutamic Acid; Humans; Kynurenine; Magnetic Resonance Spectroscopy; Male; Middle Aged; Psychiatric Status Rating Scales; Schizophrenia; Tryptophan; White Matter; Young Adult

2016
Inhibition of Large Neutral Amino Acid Transporters Suppresses Kynurenic Acid Production Via Inhibition of Kynurenine Uptake in Rodent Brain.
    Neurochemical research, 2016, Volume: 41, Issue:9

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Amino Acid Transport Systems, Neutral; Animals; Brain; Kynurenic Acid; Kynurenine; Male; Rats, Wistar; Schizophrenia; Tryptophan

2016
Kynurenine and Tryptophan Levels in Patients With Schizophrenia and Elevated Antigliadin Immunoglobulin G Antibodies.
    Psychosomatic medicine, 2016, Volume: 78, Issue:8

    Topics: Adult; Female; Gliadin; Humans; Immunoglobulin G; Kynurenine; Male; Middle Aged; Schizophrenia; Tryptophan

2016
Reversal of schizophrenia-like symptoms and immune alterations in mice by immunomodulatory drugs.
    Journal of psychiatric research, 2017, Volume: 84

    Topics: Animals; Antipsychotic Agents; Brain; Disease Models, Animal; Immunologic Factors; Immunomodulation; Interleukin-4; Interleukin-6; Ketamine; Male; Melatonin; Mice; Neuroimmunomodulation; Random Allocation; Risperidone; Schizophrenia; Schizophrenic Psychology; Tryptophan

2017
Kynurenic acid and psychotic symptoms and personality traits in twins with psychiatric morbidity.
    Psychiatry research, 2017, Volume: 247

    Topics: Bipolar Disorder; Female; Humans; Interleukin-6; Interleukin-8; Kynurenic Acid; Male; Middle Aged; Personality; Psychotic Disorders; Quinolinic Acid; Schizophrenia; Schizophrenic Psychology; Tryptophan; Tumor Necrosis Factor-alpha; Twins

2017
Physio-somatic symptoms in schizophrenia: association with depression, anxiety, neurocognitive deficits and the tryptophan catabolite pathway.
    Metabolic brain disease, 2017, Volume: 32, Issue:4

    Topics: Adolescent; Adult; Aged; Anxiety; Cognition Disorders; Depression; Female; Humans; Male; Middle Aged; Schizophrenia; Schizophrenic Psychology; Symptom Assessment; Tryptophan; Young Adult

2017
Deficit Schizophrenia Is Characterized by Defects in IgM-Mediated Responses to Tryptophan Catabolites (TRYCATs): a Paradigm Shift Towards Defects in Natural Self-Regulatory Immune Responses Coupled with Mucosa-Derived TRYCAT Pathway Activation.
    Molecular neurobiology, 2018, Volume: 55, Issue:3

    Topics: Adult; Biomarkers; Female; Humans; Immunity, Cellular; Immunoglobulin M; Kynurenic Acid; Male; Metabolism; Middle Aged; Quinolinic Acid; Schizophrenia; Schizophrenic Psychology; Signal Transduction; Tryptophan; Xanthurenates

2018
Kynurenine pathway in psychosis: evidence of increased tryptophan degradation.
    Journal of psychopharmacology (Oxford, England), 2009, Volume: 23, Issue:3

    Topics: Adult; Chromatography, High Pressure Liquid; Enzyme-Linked Immunosorbent Assay; Female; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferon-gamma; Kynurenine; Male; Middle Aged; Psychotic Disorders; Schizophrenia; Severity of Illness Index; Tryptophan; Up-Regulation

2009
Altered interactions of tryptophan metabolites in first-episode neuroleptic-naive patients with schizophrenia.
    Molecular psychiatry, 2010, Volume: 15, Issue:9

    Topics: Adolescent; Adult; Antipsychotic Agents; Female; Humans; Hydroxyindoleacetic Acid; Kynurenine; Male; Melatonin; Oxidative Stress; Schizophrenia; Serotonin; Tryptophan; Young Adult

2010
Association between genetic polymorphism of XRCC1 Arg194Trp and risk of schizophrenia.
    Psychiatry research, 2009, Sep-30, Volume: 169, Issue:2

    Topics: Arginine; Case-Control Studies; Chi-Square Distribution; DNA-Binding Proteins; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Humans; Male; Polymorphism, Single Nucleotide; Risk Factors; Schizophrenia; Tryptophan; X-ray Repair Cross Complementing Protein 1

2009
Cerebrospinal fluid analysis in affective and schizophrenic spectrum disorders: identification of subgroups with immune responses and blood-CSF barrier dysfunction.
    Journal of psychiatric research, 2010, Volume: 44, Issue:5

    Topics: Adult; Cohort Studies; Female; Humans; Immunoglobulins; International Classification of Diseases; Kynurenine; Male; Middle Aged; Mood Disorders; Neopterin; Psychiatric Status Rating Scales; Schizophrenia; Statistics, Nonparametric; Tomography, X-Ray Computed; Tryptophan

2010
Decreased plasma tryptophan and tryptophan/large neutral amino acid ratio in patients with neuroleptic-resistant schizophrenia: relationship to plasma cortisol concentration.
    Psychiatry research, 2011, Feb-28, Volume: 185, Issue:3

    Topics: Adult; Amino Acids, Neutral; Analysis of Variance; Antipsychotic Agents; Female; Humans; Hydrocortisone; Male; Psychiatric Status Rating Scales; Radioimmunoassay; Schizophrenia; Statistics as Topic; Tryptophan; Young Adult

2011
Increased levels of kynurenine and kynurenic acid in the CSF of patients with schizophrenia.
    Schizophrenia bulletin, 2012, Volume: 38, Issue:3

    Topics: Adult; Antipsychotic Agents; Benzodiazepines; Humans; Kynurenic Acid; Kynurenine; Male; Middle Aged; Olanzapine; Schizophrenia; Tryptophan; Up-Regulation; Young Adult

2012
Reversal of imbalance between kynurenic acid and 3-hydroxykynurenine by antipsychotics in medication-naïve and medication-free schizophrenic patients.
    Brain, behavior, and immunity, 2011, Volume: 25, Issue:8

    Topics: Adult; Algorithms; Antipsychotic Agents; Chromatography, High Pressure Liquid; Diagnostic and Statistical Manual of Mental Disorders; Female; Humans; Kynurenic Acid; Kynurenine; Male; Middle Aged; Patient Discharge; Schizophrenia; Schizophrenic Psychology; Spectrophotometry, Ultraviolet; Treatment Outcome; Tryptophan

2011
Development and validation of a single analytical method for the determination of tryptophan, and its kynurenine metabolites in rat plasma.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2012, Jun-01, Volume: 898

    Topics: 3-Hydroxyanthranilic Acid; Animals; Charcoal; Chromatography, High Pressure Liquid; Depression; Kynurenic Acid; Kynurenine; Linear Models; Male; ortho-Aminobenzoates; Quinolinic Acid; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Schizophrenia; Social Isolation; Solid Phase Extraction; Tandem Mass Spectrometry; Tryptophan

2012
Long-term pharmacoclinical follow-up in schizophrenic patients treated with risperidone. Plasma and red blood cell concentrations of risperidone and its 9-hydroxymetabolite and their relationship to whole blood serotonin and tryptophan, plasma homovanilli
    Progress in neuro-psychopharmacology & biological psychiatry, 2002, Volume: 26, Issue:5

    Topics: Adult; Aged; Analysis of Variance; Biomarkers; Female; Follow-Up Studies; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Methoxyhydroxyphenylglycol; Middle Aged; Risperidone; Schizophrenia; Serotonin; Tryptophan

2002
Membrane Na(+)-K+ ATPase mediated cascade in bipolar mood disorder, major depressive disorder, and schizophrenia--relationship to hemispheric dominance.
    The International journal of neuroscience, 2002, Volume: 112, Issue:8

    Topics: Adult; Bipolar Disorder; Depressive Disorder, Major; Digoxin; Dominance, Cerebral; Humans; Hydroxymethylglutaryl CoA Reductases; Magnesium; Sampling Studies; Schizophrenia; Sodium-Potassium-Exchanging ATPase; Tryptophan; Tyrosine

2002
Urinary excretion of some products of tryptophan metabolism in schizophrenic patients.
    A.M.A. archives of neurology and psychiatry, 1958, Volume: 79, Issue:3

    Topics: Humans; Schizophrenia; Tryptophan

1958
Tryptophan-nicotinic acid metabolism in schizophrenia.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1958, Volume: 97, Issue:3

    Topics: Biochemical Phenomena; Niacin; Schizophrenia; Tryptophan

1958
Ceruloplasmin, transferrin, and tryptophan in schizophrenia.
    A.M.A. archives of neurology and psychiatry, 1958, Volume: 79, Issue:6

    Topics: Ceruloplasmin; Globulins; Humans; Iron; Oxidation-Reduction; Schizophrenia; Serum Globulins; Transferrin; Tryptophan

1958
Observations of schizophrenic patients after iproniazid and tryptophan.
    A.M.A. archives of neurology and psychiatry, 1958, Volume: 80, Issue:1

    Topics: Iproniazid; Isomerism; Niacin; Nicotinic Acids; Schizophrenia; Tryptophan

1958
Tryptophan loading and excretion of 5-hydroxyindoleacetic acid in normal and schizophrenic subjects.
    Science (New York, N.Y.), 1959, Mar-27, Volume: 129, Issue:3352

    Topics: Biological Transport; Humans; Hydroxyindoleacetic Acid; Indoleacetic Acids; Schizophrenia; Tryptophan

1959
Studies in schizophrenia, V. Disturbances of protein and tryptophan metabolism and toxicity of urine.
    The Journal of mental science, 1959, Volume: 105, Issue:439

    Topics: Humans; Proteins; Schizophrenia; Tryptophan; Urine

1959
Investigations on the tryptophan content of urines from schizophrenics and other psychotic patients.
    The Journal of nervous and mental disease, 1959, Volume: 128, Issue:5

    Topics: Humans; Mental Disorders; Psychotic Disorders; Schizophrenia; Tryptophan

1959
Tryptophan metabolism in porphyria, schizophrenia, and a variety of neurologic and psychiatric diseases.
    Neurology, 1959, Volume: 9, Issue:7

    Topics: Humans; Mental Disorders; Porphyrias; Schizophrenia; Tryptophan

1959
Effects of amino acid feedings in schizophrenic patients treated with iproniazid.
    Science (New York, N.Y.), 1961, Jan-13, Volume: 133, Issue:3446

    Topics: Amino Acids; Diet; Humans; Iproniazid; Methionine; Nutrition Assessment; Schizophrenia; Tryptophan

1961
Effects of 5-hydroxytryptophan on schizophrenia.
    The Journal of mental science, 1959, Volume: 105

    Topics: 5-Hydroxytryptophan; Brain; Humans; Neurochemistry; Schizophrenia; Serotonin; Tryptophan

1959
Urinary excretion of tryptophan metabolites by schizophrenic individuals.
    The American journal of psychiatry, 1960, Volume: 117

    Topics: Humans; Schizophrenia; Tryptophan

1960
The administration of BAS, 5-HTP, and marsilid to schizophrenic patients.
    The American journal of psychiatry, 1959, Volume: 116

    Topics: 5-Hydroxytryptophan; Humans; Isoniazid; Schizophrenia; Serotonin; Tryptophan

1959
Reappraisal of biological aspects of psychiatry.
    Journal of neuropsychiatry, 1961, Volume: 3

    Topics: Biochemical Phenomena; Blood; Blood Chemical Analysis; Humans; Psychiatry; Schizophrenia; Tryptophan

1961
Chromatographic study of "Reigelhaupt" chromogens in urine.
    Journal of psychiatric research, 1962, Volume: 1

    Topics: Chromatography; Humans; Indican; Indoles; Naphthalenesulfonates; Schizophrenia; Tryptophan

1962
L-METHIONINE AND L-TRYPTOPHAN FEEDINGS IN NON-PSYCHOTIC AND SCHIZOPHRENIC PATIENTS WITH AND WITHOUT TRANYLCYPROMINE.
    The Journal of nervous and mental disease, 1963, Volume: 137

    Topics: Ammonia; Chlorides; Humans; Jews; Methionine; Neurotic Disorders; Potassium; Schizophrenia; Sodium; Toxicology; Tranylcypromine; Tryptophan; Urine

1963
URINARY INDOLES IN SCHIZOPHRENIC AND PSYCHONEUROTIC PATIENTS AFTER ADMINISTRATION OF TRANYLCYPROMINE (PARNATE) AND METHIONINE OR TRYPTOPHAN.
    The Journal of nervous and mental disease, 1963, Volume: 137

    Topics: Chromatography; Creatine; Creatinine; Humans; Indoles; Methionine; Neurotic Disorders; Placebos; Schizophrenia; Tranylcypromine; Tryptophan; Urine

1963
[CONTRIBUTION TO THE KNOWLEDGE OF THE NEUROCHEMICAL ASPECTS OF SCHIZOPHRENIA].
    Rivista sperimentale di freniatria e medicina legale delle alienazioni mentali, 1963, Jun-30, Volume: 87

    Topics: Biochemical Phenomena; Biochemistry; Humans; Metabolism; Nervous System; Schizophrenia; Tryptophan

1963
AN INVESTIGATION INTO THE PROTEIN METABOLISM OF SCHIZOPHRENICS AND ITS CLINICAL SIGNIFICANCE.
    Chinese medical journal (Peking, China : 1932), 1963, Volume: 82

    Topics: China; Chromatography; Cysteine; Cystine; Indoles; Kidney; Proteins; Renal Aminoacidurias; Schizophrenia; Tryptophan

1963
[STUDIES ON URINARY EXCRETION OF 5-HYDROXYINDOLEACETIC ACID].
    Taehan Naekwa Hakhoe chapchi = The Korean journal of internal medicine, 1963, Volume: 6

    Topics: Asian People; Child; China; Humans; Hydroxyindoleacetic Acid; Indoleacetic Acids; Korea; Metabolism; Peptic Ulcer; Republic of Korea; Schizophrenia; Serotonin; Tranquilizing Agents; Tryptophan; Urine

1963
TRYPTOPHAN METABOLISM IN SPECIAL PAIRS OF TWINS.
    Clinica chimica acta; international journal of clinical chemistry, 1964, Volume: 9

    Topics: Chromatography; Diseases in Twins; Genetics, Medical; Kynurenic Acid; Kynurenine; Metabolic Diseases; ortho-Aminobenzoates; Proteins; Schizophrenia; Spectrophotometry; Tryptophan; Urine; Xanthurenates

1964
DETERMINATION OF FREE AND TOTAL INDOLE-3-ACETIC ACID AND OF THE INDOLE INDEX.
    Clinical chemistry, 1964, Volume: 10

    Topics: Friedreich Ataxia; Humans; Indoleacetic Acids; Indoles; Intestines; Kynurenine; Metabolism; Myotonia; Phenylketonurias; Poisoning; Research; Schizophrenia; Tryptophan; Urine

1964
EXCRETION OF CATECHOLAMINES AND EXACERBATION OF SYMPTOMS IN SCHIZOPHRENIC PATIENTS.
    Journal of psychiatric research, 1964, Volume: 2

    Topics: Catecholamines; Dopamine; Epinephrine; Fluids and Secretions; Mandelic Acids; Metabolism; Methionine; Norepinephrine; Schizophrenia; Tryptophan; Urine

1964
URINARY TRYPTAMINE AND INDOLE-3-ACETIC ACID EXCRETION BY SCHIZOPHRENIC PATIENTS: USE OF THE TRYPTAMINE/INDOLE ACETIC ACID RATIO AS AN INDEX OF MONOAMINE OXIDASE INHIBITION.
    Journal of psychiatric research, 1964, Volume: 2

    Topics: Amino Acids; Fluids and Secretions; Glutamine; Glycine; Histidine; Humans; Indoleacetic Acids; Indoles; Iproniazid; Metabolism; Methionine; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Pharmacology; Phenylalanine; Schizophrenia; Tryptamines; Tryptophan; Urine

1964
INVESTIGATIONS ON THE TRYPTOPHANE METABOLISM (VIA KYNURENINE) IN SCHIZOPHRENIC PATIENTS.
    Acta psychiatrica Scandinavica, 1964, Volume: 40, Issue:3

    Topics: Amino Acids; Humans; Kynurenine; Schizophrenia; Tryptophan; Urine; Xanthurenates

1964
EFFECTS OF REDUCTION OF TRYPTOPHAN AND METHIONINE INTAKE ON URINARY INDOLE COMPOUNDS AND SCHIZOPHRENIC BEHAVIOR.
    The Journal of nervous and mental disease, 1965, Volume: 140

    Topics: Behavior; Biochemical Phenomena; Biochemistry; Dietary Proteins; Humans; Indoles; Methionine; Proteins; Schizophrenia; Tryptophan; Urine

1965
[AN ENDOGENOUS METABOLIC FACTOR IN SCHIZOPHRENIC BEHAVIOR].
    Concours medical, 1965, Apr-03, Volume: 87

    Topics: Amino Acids; Humans; Methionine; Research; Schizophrenia; Tryptophan

1965
The effects of 5-hydroxytryptophan (a serotonin precursor) in schizophrenic patients.
    The Journal of mental science, 1960, Volume: 106

    Topics: 5-Hydroxytryptophan; Schizophrenia; Serotonin; Tryptophan

1960
Metabolic studies in childhood schizophrenia. Effect of tryptophan loading on indole excretion.
    A.M.A. archives of general psychiatry, 1959, Volume: 1

    Topics: Child; Indoleacetic Acids; Indoles; Infant; Schizophrenia; Schizophrenia, Childhood; Tryptophan

1959
A nonsense mutation in the synaptogyrin 1 gene in a family with schizophrenia.
    Biological psychiatry, 2004, Jan-15, Volume: 55, Issue:2

    Topics: Blotting, Northern; Brain; Codon, Nonsense; DNA Mutational Analysis; Exons; Family Health; Female; Humans; Male; Molecular Biology; Nerve Tissue Proteins; Pedigree; Phosphoric Monoester Hydrolases; Polymorphism, Single Nucleotide; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Schizophrenia; Threonine; Tryptophan

2004
Amino acids in schizophrenia: evidence for lower tryptophan availability during treatment with atypical antipsychotics?
    Journal of neural transmission (Vienna, Austria : 1996), 2005, Volume: 112, Issue:4

    Topics: Adult; Amino Acids, Neutral; Antipsychotic Agents; Brain; Down-Regulation; Drug Resistance; Female; Humans; Male; Middle Aged; Schizophrenia; Serotonin; Tryptophan

2005
Effects of acute tryptophan depletion on negative symptoms and smoking topography in nicotine-dependent schizophrenics and nonpsychiatric controls.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2005, Volume: 30, Issue:3

    Topics: Adult; Female; Humans; Male; Middle Aged; Psychotic Disorders; Reference Values; Schizophrenia; Smoking; Tobacco Use Disorder; Tryptophan

2005
Tryptophan breakdown pathway in bipolar mania.
    Journal of affective disorders, 2007, Volume: 102, Issue:1-3

    Topics: Adult; Aspartic Acid; Bipolar Disorder; Brief Psychiatric Rating Scale; Female; Gyrus Cinguli; Humans; Kynurenic Acid; Kynurenine; Male; Schizophrenia; Severity of Illness Index; Tryptophan

2007
Alterations in kynurenine precursor and product levels in schizophrenia and bipolar disorder.
    Neurochemistry international, 2008, Volume: 52, Issue:6

    Topics: 3-Hydroxyanthranilic Acid; Adult; Biomarkers; Bipolar Disorder; Brain; Chromatography, High Pressure Liquid; Female; Gyrus Cinguli; Humans; Kynurenine; Middle Aged; Niacinamide; Predictive Value of Tests; Schizophrenia; Signal Transduction; Suicide; Tryptophan; Tryptophan Oxygenase

2008
Serotonin metabolite concentrations in cerebrospinal fluid from schizophrenic patients -- relationships to family history.
    Advances in experimental medicine and biology, 1981, Volume: 133

    Topics: Female; Humans; Hydroxyindoleacetic Acid; Male; Reference Values; Schizophrenia; Serotonin; Sex Factors; Tryptophan

1981
Cerebrospinal fluid biochemical examinations: do they reflect clinical or biological differences?
    Biological psychiatry, 1983, Volume: 18, Issue:9

    Topics: Adult; Aged; Alcoholism; Bipolar Disorder; Calcium; Depressive Disorder; Dexamethasone; Female; Homovanillic Acid; Humans; Hydrocortisone; Hydroxyindoleacetic Acid; Middle Aged; Schizophrenia; Tryptophan

1983
CSF neurochemistry in depressed, manic, and schizophrenic patients compared with that of normal controls.
    The American journal of psychiatry, 1984, Volume: 141, Issue:12

    Topics: Adolescent; Adult; Age Factors; Aged; Bipolar Disorder; Calcium; Choline; Depressive Disorder; Female; gamma-Aminobutyric Acid; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Methoxyhydroxyphenylglycol; Middle Aged; Research Design; Schizophrenia; Tryptophan; Tyrosine

1984
The effect of carbidopa and benserazide on human plasma 5-hydroxytryptophan levels.
    Journal of neural transmission, 1982, Volume: 53, Issue:1

    Topics: 5-Hydroxytryptophan; Adult; Benserazide; Carbidopa; Chlorpromazine; Dihydroxyphenylalanine; Humans; Hydrazines; Middle Aged; Parkinson Disease; Schizophrenia; Tryptophan

1982
Plasma phenylalanine, tyrosine, and tryptophan in schizophrenia.
    Archives of general psychiatry, 1983, Volume: 40, Issue:7

    Topics: Administration, Oral; Adult; Heterozygote; Humans; Infusions, Parenteral; Phenylalanine; Phenylketonurias; Schizophrenia; Tryptophan; Tyrosine

1983
Clinical response of aggressive schizophrenics to oral tryptophan.
    Biological psychiatry, 1983, Volume: 18, Issue:5

    Topics: Administration, Oral; Adult; Aggression; Humans; Male; Psychiatric Status Rating Scales; Schizophrenia; Schizophrenic Psychology; Social Adjustment; Tryptophan

1983
Cerebrospinal fluid tryptophan and brain atrophy in patients with chronic schizophrenia.
    Annals of clinical research, 1982, Volume: 14, Issue:3

    Topics: Adult; Atrophy; Brain; Female; Humans; Male; Middle Aged; Schizophrenia; Sex Factors; Tryptophan

1982
[Studies of the indolamine metabolism in endogenous psychoses].
    Sammlung zwangloser Abhandlungen aus dem Gebiete der Psychiatrie und Neurologie, 1982, Volume: 50

    Topics: Blood Platelets; Brain; Depressive Disorder; Humans; Methyltransferases; Monoamine Oxidase; Psychotic Disorders; Schizophrenia; Serotonin; Tryptophan

1982
Blood tryptophan metabolism in chronic schizophrenics.
    Archives of general psychiatry, 1981, Volume: 38, Issue:6

    Topics: Adult; Blood Platelets; Chronic Disease; Humans; Male; Monoamine Oxidase; Oxidoreductases Acting on CH-NH Group Donors; Schizophrenia; Schizophrenia, Paranoid; Serotonin; Tryptophan

1981
Middle molecular weight substances and tryptophan in cerebrospinal fluid of schizophrenic patients.
    Artificial organs, 1981, Volume: 5, Issue:2

    Topics: Adolescent; Adult; Aged; Chromatography, Gel; Female; Humans; Male; Middle Aged; Schizophrenia; Toxins, Biological; Tryptophan

1981
Measurement of the plasmatic level of free and protein-bound tryptophan in mental pathology.
    Neuropsychobiology, 1980, Volume: 6, Issue:3

    Topics: Bipolar Disorder; Humans; Reference Values; Schizophrenia; Schizophrenic Psychology; Serotonin; Tryptophan

1980
Low concentrations of serum tyrosine in neuroleptic-free schizophrenics with an early onset.
    Schizophrenia research, 1995, Volume: 14, Issue:3

    Topics: Adult; Age of Onset; Brain; Chromatography, High Pressure Liquid; Homovanillic Acid; Humans; Male; Middle Aged; Phenylalanine; Schizophrenia; Tryptophan; Tyrosine

1995
Circadian rhythm of tryptophan, serotonin, melatonin, and pituitary hormones in schizophrenia.
    Biological psychiatry, 1994, Feb-01, Volume: 35, Issue:3

    Topics: Adolescent; Adult; Aged; Antipsychotic Agents; Circadian Rhythm; Female; Growth Hormone; Humans; Hypothalamo-Hypophyseal System; Male; Melatonin; Middle Aged; Neural Inhibition; Pituitary Hormones; Prolactin; Reference Values; Schizophrenia; Schizophrenic Psychology; Serotonin; Thyrotropin; Tryptophan

1994
Tryptophanemia and tyrosinemia in adolescents with impulsive behavior.
    International clinical psychopharmacology, 1993,Summer, Volume: 8, Issue:2

    Topics: Adolescent; Aggression; Amino Acids; Anorexia Nervosa; Borderline Personality Disorder; Female; Humans; Impulsive Behavior; Male; Schizophrenia; Schizophrenic Psychology; Serotonin; Social Behavior Disorders; Tryptophan; Tyrosine

1993
Decrease in red blood cell L-tryptophan uptake in schizophrenic patients: possible link with loss of impulse control.
    Progress in neuro-psychopharmacology & biological psychiatry, 1995, Volume: 19, Issue:5

    Topics: Adult; Aged; Erythrocytes; Female; Humans; Kinetics; Male; Middle Aged; Radioligand Assay; Schizophrenia; Tryptophan

1995
Tryptophan and tyrosine catabolic pattern in neuropsychiatric disorders.
    Neurology India, 2000, Volume: 48, Issue:3

    Topics: Adult; Biogenic Monoamines; Brain Diseases; Brain Neoplasms; Digoxin; Epilepsy, Generalized; Erythrocytes; Fatty Acids, Nonesterified; Female; Glioma; Glycine Agents; Humans; Hydroxymethylglutaryl CoA Reductases; Kynurenic Acid; Magnesium; Male; Microvascular Angina; Middle Aged; Morphine; Narcotics; Nicotine; Nicotinic Agonists; Parkinson Disease; Quinolinic Acid; Schizophrenia; Serum Albumin; Sodium-Potassium-Exchanging ATPase; Strychnine; Tryptophan; Tyrosine; Ubiquinone

2000
Transmitter precursors and metabolites in human ventricular cerebrospinal fluid.
    Journal of neurochemistry, 1976, Volume: 26, Issue:3

    Topics: Cerebral Ventricles; Frontal Lobe; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Neurotic Disorders; Neurotransmitter Agents; Phenylacetates; Schizophrenia; Tryptophan; Tyrosine

1976
[Study of free and total tryptophan in the plasma. It value in psychiatry].
    L'Encephale, 1976, Volume: 2, Issue:2

    Topics: Adult; Chlorpromazine; Female; Humans; Lithium; Male; Middle Aged; Phenothiazines; Schizophrenia; Spectrometry, Fluorescence; Tryptophan

1976
[Fluorometric determination of free and total tryptophan in blood plasma].
    Annales de biologie clinique, 1977, Volume: 35, Issue:5

    Topics: Depression; Fluorometry; Heparin; Humans; Hydrogen-Ion Concentration; Protein Binding; Schizophrenia; Temperature; Tryptophan; Ultracentrifugation; Ultrafiltration

1977
Monoamine mechanisms in chronic schizophrenia: post-mortem neurochemical findings.
    The British journal of psychiatry : the journal of mental science, 1979, Volume: 134

    Topics: Aged; Brain Chemistry; Catechol O-Methyltransferase; Chronic Disease; Dopamine; Dopamine beta-Hydroxylase; Female; Humans; Hydroxyindoleacetic Acid; Kynurenine; Male; Monoamine Oxidase; Norepinephrine; Phenylacetates; Schizophrenia; Serotonin; Tryptophan; Tyrosine 3-Monooxygenase

1979
Validity of plasma factor in schizophrenia as measured by tryptophan uptake.
    Biological psychiatry, 1975, Volume: 10, Issue:3

    Topics: Aged; Alpha-Globulins; Animals; Calcium; Chickens; Complement System Proteins; Edetic Acid; Erythrocytes; Guinea Pigs; Hemolysis; Humans; Male; Mental Disorders; Middle Aged; Plasma; Schizophrenia; Temperature; Tryptophan

1975
Letter: Serum-aminoacids and brain tryptophan uptake.
    Lancet (London, England), 1975, Aug-09, Volume: 2, Issue:7928

    Topics: Amino Acids; Animals; Brain; Chlorpromazine; Humans; Rats; Schizophrenia; Serotonin; Tryptophan

1975
Biochemical aspects of schizophrenia.
    The American journal of nursing, 1975, Volume: 75, Issue:12

    Topics: Adenosine Triphosphate; Alpha-Globulins; Autoantibodies; Citric Acid Cycle; Humans; Immunoglobulin G; Schizophrenia; Serotonin; Tryptophan

1975
Recent progress in schizophrenia research.
    Lancet (London, England), 1976, Jul-17, Volume: 2, Issue:7977

    Topics: Adolescent; Animals; Brain; Diet; Dopamine; Female; Humans; Methylation; Rats; Schizophrenia; Serotonin; Tryptophan; Tyrosine

1976
[Attempt to isolate an active enzyme fraction for use in the treatment of schizophrenia].
    Vestnik Akademii meditsinskikh nauk SSSR, 1975, Issue:9

    Topics: Alpha-Globulins; Brain; Humans; Molecular Conformation; Schizophrenia; Tryptophan

1975
Tryptophan and serotonin in schizophrenia.
    Lancet (London, England), 1976, Aug-21, Volume: 2, Issue:7982

    Topics: Brain; Humans; Receptors, Serotonin; Schizophrenia; Serotonin; Tryptophan

1976
Comparison of the visually evoked response in drug-free chronic schizophrenic patients and normal controls.
    Electroencephalography and clinical neurophysiology, 1979, Volume: 46, Issue:2

    Topics: Adult; Electroencephalography; Evoked Potentials; Humans; Male; Occipital Lobe; Photic Stimulation; Reaction Time; Schizophrenia; Schizophrenic Psychology; Tryptophan; Visual Perception

1979
Transmitters and related substances in brain material: an index of terminal and/or post-mortem biochemical change.
    Lancet (London, England), 1978, Jan-21, Volume: 1, Issue:8056

    Topics: Brain; Carboxy-Lyases; Cauda Equina; Glutamate Decarboxylase; Humans; Huntington Disease; Neurotransmitter Agents; Nucleus Accumbens; Postmortem Changes; Schizophrenia; Tryptophan

1978
Brain tryptophan metabolism in schizophrenia: a post mortem study of metabolites of the serotonin and kynurenine pathways in schizophrenic and control subjects.
    Psychopharmacology, 1979, Apr-25, Volume: 62, Issue:3

    Topics: Aged; Aging; Brain; Female; Humans; Hydroxyindoleacetic Acid; Kynurenine; Male; Middle Aged; Myocardial Infarction; Postmortem Changes; Schizophrenia; Serotonin; Sex Factors; Tryptophan

1979
Distribution of tryptophan in erythrocytes, leukocytes and thrombocytes, and its binding to plasma albumin.
    Journal of neural transmission. Supplementum, 1979, Issue:15

    Topics: Biological Transport, Active; Blood Platelets; Depression; Erythrocytes; Humans; Leukocytes; Schizophrenia; Serum Albumin; Tryptophan

1979
The influence of oral tryptophan on cortical evoked responses in normals and schizophrenics.
    Journal of neural transmission. Supplementum, 1979, Issue:15

    Topics: Administration, Oral; Brain; Dose-Response Relationship, Drug; Electroencephalography; Evoked Potentials; Humans; Male; Schizophrenia; Tryptophan; Vision, Ocular

1979
Blood-brain movements of tryptophan and tyrosine in manic-depressive illness and schizophrenia.
    Journal of neural transmission. Supplementum, 1979, Issue:15

    Topics: Adult; Bipolar Disorder; Blood-Brain Barrier; Brain; Dihydroxyphenylalanine; Humans; Middle Aged; Schizophrenia; Serotonin; Tryptophan; Tyrosine

1979
[Psychopharmacology of tryptophan (author's transl)].
    Pathologie-biologie, 1977, Volume: 25, Issue:8

    Topics: Animals; Bipolar Disorder; Depression; Humans; Mental Disorders; Parkinson Disease; Schizophrenia; Serotonin; Sleep; Tryptophan

1977
[Stimulating effect of schizophrenic patients' plasma on the cellular incorportation of tryptophan in vitro].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1979, Volume: 79, Issue:7

    Topics: Adenylate Kinase; Adult; Animals; Chickens; Creatine Kinase; Erythrocytes; Female; Hemolysis; Humans; Immune Sera; L-Lactate Dehydrogenase; Male; Middle Aged; Schizophrenia; Tryptophan

1979
Lithium: clinical effects and cerebrospinal fluid acid monoamine metabolites.
    Communications in psychopharmacology, 1977, Volume: 1, Issue:2

    Topics: Adult; Affective Symptoms; Aged; Biogenic Amines; Bipolar Disorder; Depression; Electroencephalography; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Lithium; Male; Middle Aged; Probenecid; Psychiatric Status Rating Scales; Schizophrenia; Tryptophan

1977
[Uptake of tryptophan and tyrosine in some cases of manic depressive psychosis and schizophrenia (author's transl)].
    Neuropsychobiology, 1978, Volume: 4, Issue:2

    Topics: Bipolar Disorder; Brain; Humans; Protein Binding; Schizophrenia; Tryptophan; Tyrosine

1978
Classically conditioned autonomic discrimination and tryptophan uptake in chronic schizophrenia.
    Psychophysiology, 1978, Volume: 15, Issue:2

    Topics: Adult; Autonomic Nervous System; Chronic Disease; Conditioning, Classical; Discrimination Learning; Humans; Male; Schizophrenia; Tryptophan

1978
Schizophrenia, rheumatoid arthritis and trytophan metabolism.
    The Journal of clinical psychiatry, 1978, Volume: 39, Issue:6

    Topics: Arthritis, Rheumatoid; Female; Humans; Male; Methionine; Methylation; Monoamine Oxidase; Protein Binding; Schizophrenia; Serotonin; Synovial Fluid; Tryptamines; Tryptophan

1978
A study of relationships of serum glucose, insulin, free fatty acids, and free and total tryptophan to mental illness.
    Biological psychiatry, 1978, Volume: 13, Issue:2

    Topics: Adolescent; Adult; Blood Glucose; Fatty Acids, Nonesterified; Female; Glucose; Glucose Tolerance Test; Hallucinations; Humans; Insulin; Male; Mental Disorders; Middle Aged; Neurotic Disorders; Schizophrenia; Time Factors; Tryptophan

1978
[Effect of schizophrenic patients' plasma on 14C-tryptophan incorporation in chicken erythrocytes].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1978, Volume: 78, Issue:6

    Topics: Adult; Animals; Chickens; Erythrocytes; Female; Humans; Immune Sera; Male; Middle Aged; Schizophrenia; Tryptophan

1978
Pellagra and mental disturbance.
    The Proceedings of the Nutrition Society, 1978, Volume: 37, Issue:2

    Topics: Animals; Brain; Diet; Hartnup Disease; Humans; Mental Disorders; Nicotinic Acids; Pellagra; Pyridoxine; Rats; Schizophrenia; Tryptophan; Zea mays

1978
[Schizophrenia and addiction].
    L'Encephale, 1978, Volume: 4, Issue:4

    Topics: Adult; Amphetamines; Cybernetics; Dopamine; Endorphins; Humans; Lysergic Acid Diethylamide; Male; Norepinephrine; Receptors, Dopamine; Receptors, Serotonin; Schizophrenia; Schizophrenic Psychology; Substance-Related Disorders; Tryptophan

1978
Cerebral circulation and EEG alpha frequency in relation to daily fluctuations in psychotic behavior.
    The Journal of nervous and mental disease, 1976, Volume: 162, Issue:3

    Topics: Adult; Alpha Rhythm; Bipolar Disorder; Circadian Rhythm; Female; Humans; Longitudinal Studies; Menstruation; Middle Aged; Periodicity; Phenelzine; Psychiatric Status Rating Scales; Psychotic Disorders; Remission, Spontaneous; Schizophrenia; Schizophrenia, Catatonic; Time Factors; Tryptophan

1976
An electrophysiological study on the effects of tryptophan and cortisol on schizophrenic and other mentally ill patient groups and on normal subjects.
    Biological psychiatry, 1976, Volume: 11, Issue:4

    Topics: Adolescent; Adult; Age Factors; Animals; Brain; Carbon Dioxide; Electrophysiology; Female; Frontal Lobe; Humans; Hydrocortisone; Hydroxylation; Indoles; Male; Menopause; Mental Disorders; Middle Aged; Psychotropic Drugs; Schizophrenia; Sex Factors; Tryptophan

1976
Insulin coma therapy: decrease of plasma tryptophan in man.
    Journal of neural transmission, 1976, Volume: 39, Issue:4

    Topics: Adult; Convulsive Therapy; Fatty Acids, Nonesterified; Female; Glucose; Humans; Hypoglycemia; Insulin Coma; Male; Schizophrenia; Tryptophan; Tyrosine

1976
Precursors and metabolites of 5-hydroxytryptamine and dopamine in the ventricular cerebrospinal fluid of psychiatric patients.
    Psychological medicine, 1976, Volume: 6, Issue:3

    Topics: Adult; Aged; Anxiety Disorders; Brain Diseases; Cerebral Ventricles; Depression; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Mental Disorders; Middle Aged; Obsessive-Compulsive Disorder; Phenylacetates; Schizophrenia; Tryptophan; Tyrosine

1976
Schizophrenia, a disorder of tryptophan metabolism.
    Acta psychiatrica Scandinavica. Supplementum, 1975, Volume: 258

    Topics: Catecholamines; Diet; Hallucinogens; Humans; Indoles; Metabolism, Inborn Errors; Monoamine Oxidase; Schizophrenia; Tryptophan

1975
Urinary excretion of n,n-dimethylated tryptamines in chronic schizophrenia. A review of the present status of the hypothesis.
    Canadian Psychiatric Association journal, 1976, Volume: 21, Issue:8

    Topics: 5-Methoxytryptamine; Adult; Bufotenin; Chronic Disease; Epinephrine; Female; Humans; Hydroxyindoleacetic Acid; Methylation; Middle Aged; N,N-Dimethyltryptamine; Norepinephrine; Phenelzine; Schizophrenia; Serotonin; Tryptamines; Tryptophan

1976
[Hypothetical concept: the physiopathological entity of monoaminergic psychoses].
    L'Encephale, 1975, Volume: 1, Issue:4

    Topics: 5-Hydroxytryptophan; Amino Acids; Animals; Behavior, Animal; Bipolar Disorder; Blood-Brain Barrier; Catecholamines; Diet; Humans; Levodopa; Neurons; Rats; Schizophrenia; Serotonin; Sexual Behavior; Tryptophan; Tyrosine

1975
Changes in serum tryptophan and albumin binding of tryptophan in chlorpromazine-treated chronic schizophrenics on withdrawal and restoration of drug therapy.
    Psychological medicine, 1975, Volume: 5, Issue:4

    Topics: Adult; Amino Acids; Brain; Chlorpromazine; Chronic Disease; Fatty Acids, Nonesterified; Humans; Male; Middle Aged; Placebos; Protein Binding; Schizophrenia; Serotonin; Serum Albumin; Tryptophan

1975
A case of drug-drug interaction involving clozapine.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1991, Volume: 36, Issue:3

    Topics: Adult; Ascorbic Acid; Clozapine; Drug Eruptions; Drug Interactions; Humans; Male; Niacin; Schizophrenia; Schizophrenic Psychology; Tryptophan

1991
L-tryptophan in neuroleptic-induced akathisia.
    Biological psychiatry, 1990, Mar-15, Volume: 27, Issue:6

    Topics: Adult; Akathisia, Drug-Induced; Antipsychotic Agents; Benztropine; Humans; Male; Middle Aged; Parasympatholytics; Pilot Projects; Psychomotor Agitation; Schizophrenia; Tryptophan

1990
From the Food and Drug Administration.
    JAMA, 1990, Jan-12, Volume: 263, Issue:2

    Topics: Clozapine; Dibenzazepines; Humans; Methadone; Schizophrenia; Tryptophan; United States; United States Food and Drug Administration

1990
Relationship between tryptophan and serotonin concentrations in postmortem human brain.
    Medical biology, 1987, Volume: 65, Issue:4

    Topics: Brain; Humans; Hydroxyindoleacetic Acid; Indoles; Schizophrenia; Serotonin; Suicide; Tryptophan

1987
Cerebrospinal fluid cholecystokinin, bombesin and somatostatin in schizophrenia and normals.
    Progress in neuro-psychopharmacology & biological psychiatry, 1985, Volume: 9, Issue:1

    Topics: Adolescent; Adult; Bombesin; Cholecystokinin; Female; Humans; Hydrocortisone; Male; Middle Aged; Peptides; Pimozide; Probenecid; Schizophrenia; Somatostatin; Tryptophan

1985
Rheumatoid arthritis and schizophrenia: are they mutually exclusive?
    Seminars in arthritis and rheumatism, 1985, Volume: 15, Issue:1

    Topics: Anti-Inflammatory Agents; Antipsychotic Agents; Arthritis, Rheumatoid; Endorphins; Environment; Humans; Prostaglandins; Schizophrenia; Serotonin; Tryptophan

1985
Endocrine responses to tryptophan infusion in schizophrenic patients treated with neuroleptics.
    Psychoneuroendocrinology, 1987, Volume: 12, Issue:3

    Topics: Adult; Antipsychotic Agents; Female; Growth Hormone; Humans; Male; Pituitary Gland, Anterior; Prolactin; Schizophrenia; Tryptophan

1987
Neurotransmitter amino acids in post-mortem brains of chronic schizophrenic patients.
    Psychiatry research, 1987, Volume: 22, Issue:4

    Topics: Adult; Aged; Amino Acids; Amygdala; Brain Chemistry; Chronic Disease; Female; gamma-Aminobutyric Acid; Humans; Male; Middle Aged; Neurotransmitter Agents; Postmortem Changes; Schizophrenia; Tryptophan

1987
Responses of prolactin and growth hormone to L-tryptophan infusion: effects in normal subjects and schizophrenic patients receiving neuroleptics.
    Psychopharmacology, 1985, Volume: 86, Issue:1-2

    Topics: Adult; Cyproheptadine; Female; Growth Hormone; Humans; Hypothalamo-Hypophyseal System; Male; Prolactin; Reference Values; Schizophrenia; Serotonin; Sleep Stages; Synaptic Transmission; Tryptophan

1985
[Alpha-rhythm asymmetry of schizophrenic patients before and after tryptophan administration].
    Psychiatrie, Neurologie, und medizinische Psychologie, 1987, Volume: 39, Issue:10

    Topics: Acute Disease; Adult; Alpha Rhythm; Dominance, Cerebral; Female; Hallucinations; Humans; Male; Schizophrenia; Schizophrenia, Paranoid; Schizophrenic Psychology; Tryptophan

1987
[Tryptophan-loading in schizophrenia and endogenous depression].
    Psychiatrie, Neurologie, und medizinische Psychologie, 1987, Volume: 39, Issue:1

    Topics: Administration, Oral; Adult; Depressive Disorder; Female; Humans; Kinetics; Male; Schizophrenia; Tryptophan

1987
Schizophrenia--new concepts.
    Southern medical journal, 1971, Volume: 64, Issue:6

    Topics: Alpha-Globulins; Brain; Chronic Disease; Humans; Lipoproteins; Schizophrenia; Synaptic Transmission; Tryptophan

1971
Conformation of a unique plasma protein in schizophrenia.
    Biological psychiatry, 1971, Volume: 3, Issue:2

    Topics: 5-Hydroxytryptophan; Adult; Alpha-Globulins; Amino Acids; Animals; Brain; Brain Chemistry; Chemical Phenomena; Chemistry; Chickens; Chromatography, DEAE-Cellulose; Electrophoresis, Disc; Humans; Male; Nerve Tissue Proteins; Optical Rotatory Dispersion; Schizophrenia; Tryptophan

1971
The effect of the plasma factor on the uptake of amino acids by neural tissue.
    Biological psychiatry, 1972, Volume: 5, Issue:2

    Topics: Adolescent; Adult; Alpha-Globulins; Animals; Brain; Brain Chemistry; Calcium; Histocytochemistry; Humans; In Vitro Techniques; Male; Neurons; Oxygen; Potassium; Rats; Schizophrenia; Sodium; Time Factors; Tryptophan

1972
Conformational variation in a human plasma lipoprotein.
    Biochemistry, 1972, Dec-19, Volume: 11, Issue:26

    Topics: Adult; Alpha-Globulins; Amino Acids; Animals; Biological Transport; Centrifugation, Density Gradient; Cholesterol; Chromatography; Circular Dichroism; Electrophoresis; Electrophoresis, Disc; Humans; Lipids; Lipoproteins; Male; Middle Aged; Molecular Weight; Oleic Acids; Optical Rotatory Dispersion; Protein Conformation; Rats; Schizophrenia; Stearic Acids; Tryptophan

1972
Electrophysiological phenomena associated with the S-protein system in normal and schizophrenic subjects.
    Biological psychiatry, 1973, Volume: 7, Issue:2

    Topics: 5-Hydroxytryptophan; Adult; Alpha-Globulins; Animals; Chickens; Electrophysiology; Erythrocytes; Female; Frontal Lobe; Glutamates; Humans; In Vitro Techniques; Male; Middle Aged; Proline; Protein Conformation; Pyrrolidonecarboxylic Acid; Rats; Schizophrenia; Serotonin; Tryptophan

1973
Distribution and mechanism of action of the anti-S protein in human brain.
    Biological psychiatry, 1973, Volume: 7, Issue:1

    Topics: Adult; Alpha-Globulins; Animals; Brain; Brain Chemistry; Chickens; Erythrocytes; Humans; In Vitro Techniques; Middle Aged; Nerve Tissue Proteins; Schizophrenia; Tissue Extracts; Tryptophan

1973
The effects of the S-protein on intracranial self-stimulation in the rat.
    Biological psychiatry, 1974, Volume: 8, Issue:2

    Topics: Alpha-Globulins; Animals; Behavior, Animal; Cattle; Conditioning, Operant; Electric Stimulation; Humans; Hypothalamus; Male; Molecular Weight; N,N-Dimethyltryptamine; Protein Conformation; Rats; Reinforcement Schedule; Reward; Schizophrenia; Self Stimulation; Tryptophan

1974
A theory of neuronal malfunction in schizophrenia.
    The American journal of psychiatry, 1969, Volume: 126, Issue:2

    Topics: Alpha-Globulins; Amino Acids; Animals; Antigens; Autoantibodies; Beta-Globulins; Cell Membrane Permeability; Chickens; Erythrocytes; Glutamates; Hemolysin Proteins; Humans; In Vitro Techniques; Neurons; Phenylalanine; Rats; Schizophrenia; Synapses; Synaptic Transmission; Tryptophan

1969
Amino acid transport and the plasma factor in schizophrenia.
    Biological psychiatry, 1969, Volume: 1, Issue:3

    Topics: 5-Hydroxytryptophan; Alpha-Globulins; Amino Acids; Animals; Biological Transport; Carbon Isotopes; Chickens; Erythrocytes; Glutamates; Humans; Ouabain; Schizophrenia; Tryptophan

1969
Schizophrenic behavior and urinary tryptophan metabolites associated with cysteine given with and without a monoamine oxidase inhibitor (tranylcypromine).
    Life sciences, 1967, Mar-01, Volume: 6, Issue:5

    Topics: Adult; Catatonia; Creatine; Cysteine; Humans; Indoleacetic Acids; Male; Middle Aged; Niacinamide; Paranoid Disorders; Schizophrenia; Tranylcypromine; Tryptamines; Tryptophan

1967
[Tryptophan-nicotinic acid metabolism in psychiatric diseases].
    Acta vitaminologica et enzymologica, 1968, Volume: 22, Issue:3

    Topics: Adult; Child; Child, Preschool; Chromatography; Down Syndrome; Female; Humans; Intellectual Disability; Male; Nicotinic Acids; Schizophrenia; Sex Factors; Tryptophan

1968
Serum levels of phenylalanine and tyrosine in Huntington's chorea.
    Acta psychiatrica Scandinavica. Supplementum, 1971, Volume: 221

    Topics: Adult; Aged; Analysis of Variance; Antidepressive Agents; Body Weight; Dopamine; Female; Humans; Huntington Disease; Male; Middle Aged; Norepinephrine; Parasympatholytics; Phenylalanine; Psychotic Disorders; Reserpine; Schizophrenia; Tryptophan; Tyrosine

1971
Serum from schizophrenic patients. Effect on cellular lactate stimulation and tryptophan uptake.
    Archives of general psychiatry, 1973, Volume: 29, Issue:6

    Topics: Animals; Blood; Chickens; Chromatography, Affinity; Complement System Proteins; Edetic Acid; Erythrocytes; Guinea Pigs; Hemolysis; Humans; Immunoglobulin M; Lactates; Lipoproteins; Lipoproteins, LDL; Male; Rabbits; Schizophrenia; Tryptophan

1973
[Effect of tryptophan on the somatotropic hormone during sleep in schizophrenics].
    Bollettino della Societa italiana di biologia sperimentale, 1973, Dec-30, Volume: 49, Issue:24

    Topics: Adult; Chronic Disease; Circadian Rhythm; Growth Hormone; Humans; Middle Aged; Pituitary Gland; Schizophrenia; Sleep; Sleep Stages; Sleep, REM; Tryptophan

1973
Serum tryptophan binding in chlorpromazine-treated chronic schizophrenics.
    Journal of neurochemistry, 1974, Volume: 22, Issue:5

    Topics: Chlorpromazine; Chronic Disease; Diffusion; Fatty Acids, Nonesterified; Humans; Liver; Male; Orphenadrine; Protein Binding; Schizophrenia; Serum Albumin; Time Factors; Tryptophan; Tryptophan Oxygenase

1974
The effect of insulin load on plasma tryptophan levels in schizophrenic patients.
    Activitas nervosa superior, 1974, Volume: 16, Issue:3

    Topics: Depression, Chemical; Humans; Insulin; Schizophrenia; Tryptophan

1974
Cerebral hemodynamic effects of chronic tryptophan feeding in man as measured by quantified cerebral impedance plethysmography.
    Biological psychiatry, 1974, Volume: 9, Issue:2

    Topics: Administration, Oral; Adult; Blood Circulation Time; Blood Pressure; Carotid Arteries; Cerebrovascular Circulation; Female; Heart Rate; Humans; Middle Aged; Phenelzine; Plethysmography, Impedance; Regional Blood Flow; Schizophrenia; Tryptophan; Vascular Resistance; Vertebral Artery

1974
Fluorometric measurement of 5-hydroxyindoleacetic acid (5HIAA) and tryptophan in human CSF: effects of high doses of probenecid.
    Biological psychiatry, 1974, Volume: 9, Issue:1

    Topics: Administration, Oral; Adolescent; Adult; Bipolar Disorder; Brain Chemistry; Depression; Female; Fluorometry; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Probenecid; Schizophrenia; Tryptophan

1974
Plasma tryptophan tolerance curves in drug free normal controls, schizophrenic patients and prisoner volunteers.
    Journal of psychiatric research, 1974, Volume: 10, Issue:3-4

    Topics: Acute Disease; Administration, Oral; Adult; Chlorpromazine; Chronic Disease; Circadian Rhythm; Depression; Fasting; Food; Half-Life; Humans; Male; Middle Aged; Personality Disorders; Prisoners; Schizophrenia; Tryptophan

1974
Abnormalities in tryptophan metabolites in schizophrenia.
    Psychopharmacology bulletin, 1974, Volume: 10, Issue:3

    Topics: Animals; Cattle; Electrodes, Implanted; Humans; Proteins; Rats; Schizophrenia; Tryptophan

1974
Experimental data to the pathogenesis of cryptopyrrole excretion in schizophrenia, I.
    Acta physiologica Academiae Scientiarum Hungaricae, 1972, Volume: 42, Issue:1

    Topics: Chromatography; Depression; Epilepsy; Humans; Mass Screening; Paranoid Disorders; Periodicity; Porphyrins; Psychotic Disorders; Pyrroles; Schizophrenia; Tryptophan

1972
Low plasma tryptophan levels in recently hospitalized schizophrenics.
    Biological psychiatry, 1973, Volume: 6, Issue:2

    Topics: Acute Disease; Adolescent; Adult; Age Factors; Aged; Bipolar Disorder; Chronic Disease; Depression; Diet; Female; Hospitalization; Humans; Length of Stay; Male; Middle Aged; Phenylalanine; Racial Groups; Schizophrenia; Sex Factors; Tryptophan; Tyrosine

1973
Association of plasma tryptophan levels with clinical change in female schizophrenic patients.
    Biological psychiatry, 1973, Volume: 6, Issue:2

    Topics: Acute Disease; Adolescent; Adult; Aged; Chronic Disease; Female; Hospitalization; Humans; Length of Stay; Male; Middle Aged; Phenylalanine; Racial Groups; Remission, Spontaneous; Schizophrenia; Sex Factors; Tryptophan; Tyrosine

1973
[Biochemical study of a schizophreniac].
    Lille medical : journal de la Faculte de medecine et de pharmacie de l'Universite de Lille, 1973, Volume: 18, Issue:10

    Topics: Adult; Cysteine; Humans; Male; Methylation; Monoamine Oxidase Inhibitors; Phenylalanine; Schizophrenia; Transferases; Tryptophan

1973
Relationship of dietary tryptophan and niacin to tryptophan metabolism in schizophrenics and nonschizophrenics.
    The American journal of clinical nutrition, 1974, Volume: 27, Issue:6

    Topics: Acetates; Aminohippuric Acids; Diet; Female; Humans; Hydroxyindoleacetic Acid; Indican; Indoles; Kynurenic Acid; Kynurenine; Male; Nicotinic Acids; ortho-Aminobenzoates; Schizophrenia; Tryptophan; Tryptophan Hydroxylase; Tryptophan Oxygenase; Vitamin B 6 Deficiency; Xanthurenates

1974
Amines and aphrodisiacs in chronic schizophrenia.
    The Journal of nervous and mental disease, 1972, Volume: 155, Issue:4

    Topics: Adult; Aphrodisiacs; Epinephrine; Evaluation Studies as Topic; Female; Humans; Hydroxyindoleacetic Acid; Middle Aged; Phenelzine; Psychiatric Status Rating Scales; Schizophrenia; Sexual Behavior; Tranquilizing Agents; Tryptamines; Tryptophan

1972
Detection of psychotomimetic N,N-dimethylated indoleamines in the urine of four schizophrenic patients.
    The British journal of psychiatry : the journal of mental science, 1970, Volume: 117, Issue:539

    Topics: 5-Hydroxytryptophan; Adult; Chromatography, Gas; Chromatography, Paper; Chromatography, Thin Layer; Cysteine; Hallucinogens; Humans; Male; Methionine; Middle Aged; Schizophrenia; Serotonin; Tranylcypromine; Tryptamines; Tryptophan

1970
Methionine and tryptophan loading in schizophrenic patients receiving a MAO inhibitor: correlation of behavioral and biochemical changes.
    Biological psychiatry, 1969, Volume: 1, Issue:3

    Topics: Adult; Creatinine; Drug Synergism; Humans; Indoleacetic Acids; Male; Methionine; Middle Aged; Schizophrenia; Schizophrenic Psychology; Tranylcypromine; Tryptamines; Tryptophan

1969
Comparative behavioral and biochemical effects of tranylcypromine and cysteine on normal controls and schizophrenic patients.
    Life sciences. Pt. 1: Physiology and pharmacology, 1970, Sep-15, Volume: 9, Issue:18

    Topics: Adult; Amines; Behavior; Chromatography, Gas; Chromatography, Ion Exchange; Chromatography, Thin Layer; Creatinine; Cysteine; Diet; Hallucinogens; Humans; Indoleacetic Acids; Male; Methionine; Middle Aged; Schizophrenia; Spectrum Analysis; Tranylcypromine; Tryptamines; Tryptophan

1970
Electrophysiological studies on the brain. Effects of nucleotide and tryptophan metabolites as modified by polyamines in normal and psychotic subjects.
    Diseases of the nervous system, 1970, Volume: 31, Issue:11

    Topics: Amines; Anxiety; Brain; Capillary Permeability; Electrophysiology; Feedback; Humans; Neurotic Disorders; Nucleoproteins; Nucleotides; Psychotic Disorders; Schizophrenia; Tranquilizing Agents; Tryptophan

1970
Cerebrospinal fluid 5-hydroxyindoles and behavior after L-tryptophan and pyridoxine adminstration to psychiatric patients.
    Neuropharmacology, 1970, Volume: 9, Issue:6

    Topics: Adolescent; Adult; Behavior; Depression; Female; Humans; Indoles; Male; Middle Aged; Psychological Tests; Pyridoxine; Schizophrenia; Tryptophan

1970
[The effect of phenamine on medicinal parkinsonism and retardation of movement upon stimulation of the caudate nucleus (a clinico-experimental study)].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1970, Volume: 70, Issue:9

    Topics: Amphetamine; Caudate Nucleus; Female; Haloperidol; Humans; Male; Parkinson Disease; Parkinson Disease, Secondary; Schizophrenia; Tryptophan

1970
[Blood serum tryptophan in schizophrenic patients and the dependence of its level on treatment with neuroleptics].
    Annales Academiae Medicae Stetinensis, 1970, Volume: 16

    Topics: Adolescent; Adult; Female; Humans; Male; Middle Aged; Schizophrenia; Tranquilizing Agents; Tryptophan

1970
[Basic research in schizophrenia].
    Ugeskrift for laeger, 1971, Jul-16, Volume: 133, Issue:28

    Topics: Adrenal Glands; Amphetamine; Chemical Phenomena; Chemistry; Dopamine; Female; Hirsutism; Humans; Monoamine Oxidase Inhibitors; Phenethylamines; Schizophrenia; Thyroid Gland; Tryptamines; Tryptophan

1971
Excretion of indoleamines in schizophrenia.
    International journal of neurology, 1967, Volume: 6, Issue:1

    Topics: Amines; Humans; Indoles; Methionine; Monoamine Oxidase Inhibitors; Schizophrenia; Tryptamines; Tryptophan

1967
Screening for aminoacidurias in psychiatric inpatients.
    Archives of general psychiatry, 1969, Volume: 21, Issue:1

    Topics: Affective Symptoms; Amino Acid Metabolism, Inborn Errors; Brain Damage, Chronic; Depression; Drug Synergism; Hartnup Disease; Homocystinuria; Hospitals, Psychiatric; Humans; Intellectual Disability; Mass Screening; Massachusetts; Mental Disorders; Methionine; Monoamine Oxidase Inhibitors; Neurotic Disorders; Personality Disorders; Phenylketonurias; Schizophrenia; Substance-Related Disorders; Tryptophan

1969
Biochemical correlates of behavior in schizophrenic patients. Schizophrenic patients receiving tryptophan and methionine or methionine together with a monoamine oxidase inhibitor.
    Archives of general psychiatry, 1965, Volume: 13, Issue:6

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Catecholamines; Humans; Male; Methionine; Middle Aged; Norepinephrine; Psychopharmacology; Schizophrenia; Tranylcypromine; Tryptamines; Tryptophan; Urine

1965
Antipyridoxine effect of D-penicillamine in schizophrenic men.
    The American journal of clinical nutrition, 1966, Volume: 19, Issue:5

    Topics: Adult; Ceruloplasmin; Copper; Fluorometry; Humans; Male; Middle Aged; Penicillamine; Pyridoxine; Schizophrenia; Tryptophan; Xanthurenates

1966