tryptophan and Parkinson Disease

tryptophan has been researched along with Parkinson Disease in 105 studies

Research

Studies (105)

TimeframeStudies, this research(%)All Research%
pre-199059 (56.19)18.7374
1990's8 (7.62)18.2507
2000's8 (7.62)29.6817
2010's20 (19.05)24.3611
2020's10 (9.52)2.80

Authors

AuthorsStudies
Boros, FA; Vécsei, L1
Alavinejad, N; Apetz, N; Drzezga, A; Endepols, H; Neumaier, B; Vus, S; Zischler, J; Zlatopolskiy, BD1
Asakawa, T; Chen, W; Jia, X; Qin, W; Shi, Y1
Dai, L; Du, Z; Fang, Y; Jiang, H; Li, F; Li, H; Liu, C; Liu, Z; Meng, L; Tian, Y; Wang, Z; Xiong, M; Yan, Z; Yu, T; Yuan, X; Zhang, J; Zhang, Z1
Boda, K; Klivényi, P; Maszlag-Török, R; Molnár, K; Somogyvári, F; Szolnoki, Z; Tanaka, M; Török, N; Vécsei, L1
Fathi, M; Hajibeygi, R; Jazi, K; Klegeris, A; McElhinney, A; Sayehmiri, F; Shool, S; Sodeifian, F; Tavasol, A; Tavirani, MR; Vakili, K; Yaghoobpoor, S1
Augustin, A; Balasubramanian, K; Bjarnason, I; Charlett, A; Chekmeneva, E; DeSouza, N; Dobbs, RJ; Dobbs, SM; Guennec, AL; Hayee, BH; Ibrahim, MAA; Kendler-Rhodes, A; Lewis, M; Ma, Y; Mullish, BH; Ryan, S; Takis, P; Taylor, D; Tucker, RM; Umamahesan, C; Weller, C; Whelan, K1
Tanaka, M; Toldi, J; Vécsei, L1
Brundin, L; Brundin, P; Burmeister, AR; Capan, CD; Du, G; Escobar Galvis, ML; Heilman, PL; Huang, X; Krzyzanowski, S; Lewis, MM; Wang, EW1
Chen, S; Gao, Y; Liu, Y; Tan, J; Wang, Y; Wu, H; Xiao, Z; Yan, H; Yi, S1
Blackie, J; Chu, S; Ellis, M; Hayes, M; Kennerson, M; Lubomski, M; Nicholson, G; O'Sullivan, JD1
Amoussouvi, A; Haralampiev, I; Herrmann, A; Stöckl, M; Wietek, J1
Anderson, G; Maes, M2
Bezard, E; Ko, WK; Li, Q1
Majláth, Z; Vécsei, L1
Cai, Z; Chen, LL; Chua, KK; Li, M; Liu, LF; Luan, H; Meng, N; Mok, VC; Song, JX; Tang, Z; Xie, LX1
Barros, M; Curtis, JE; Gruschus, JM; Heinrich, F; Jiang, Z; Lee, JC; Pfefferkorn, CM; Sidransky, E; Yap, TL1
Cintra, AC; Martins, NM; Sampaio, SV; Santos, AC; Santos, NA; Sartim, MA1
Leavitt, BR; Mazarei, G1
Eskow Jaunarajs, KL; Figge, DA; Standaert, DG1
Anderson, G; Berk, M; Carvalho, AF; Maes, M; Seo, M1
Cryan, JF; Dinan, TG1
Anderson, TJ; Dalrymple-Alford, JC; Mace, JL; Porter, RJ; Wesnes, KA1
Anderson, TJ; Dalrymple-Alford, JC; Mace, JL; Porter, RJ1
Kincses, ZT; Szabó, N; Toldi, J; Vécsei, L1
Li, W; Yang, C; Yang, J; Zhou, Z1
Boskovic, R; Clark, M; Houle, S; Kish, SJ; Meyer, JH; Rabiner, EA; Rusjan, P; Sacher, J; Soliman, A; Wilson, AA1
Tan, L; Yu, JT1
Augustin, J; Ayrignac, X; Campion, D; Clanet, M; Coutant, S; Defebvre, L; Frébourg, T; Guyant-Maréchal, L; Hannequin, D; Krystkowiak, P; Labauge, P; Le Ber, I; Lefaucheur, R; Legallic, S; Maltête, D; Martinaud, O; Nicolas, G; Pariente, J; Pottier, C; Rousseau, S; Rovelet-Lecrux, A; Vaschalde, Y1
Fuchs, D; Leblhuber, F; Neurauter, G1
Kurup, PA; Kurup, RK1
Bodner, N; Edridge, S; Fink, AL; Hong, DP; Kaylor, J; Yamin, G1
Leentjens, AF; Scholtissen, B; Verhey, FR; Vreeling, FW1
Adam, JJ; Leentjens, AF; Prickaerts, J; Scholtissen, B; Verhey, FR1
Miller, EM; Nieburg, HA1
Rodgers, KJ; Shiozawa, N1
Wurtman, RJ1
Aguado, EG; de Yebenes, JG; Mena, MA1
Botteri, A; Hamfelt, A; Söderhjelm, L1
Anderson, GM; Chouinard, G; Gauthier, S; Purdy, WC; Young, SN1
Lehmann, J4
Riederer, P1
Beasley, BL; Chase, TN; Davenport, RW; Nutt, JG1
Bryant, RC1
Abe, T; Hamato, H; Takahashi, J; Takahashi, S; Tohgi, H1
Hesselink, JM1
Arun, P; Kurup, PA; Leelamma, S; Ravikumar, A1
Arun, P; Deepadevi, KV; Kurup, PA; Manojkumar, V; Ravikumar, A1
Fuchs, D; Leblhuber, F; Widner, B1
Daniel, PM; Moorhouse, RS; Pratt, OE1
Boulu, R; Poitou, P1
Bender, DA; Earl, CJ; Lees, AJ1
Olholm-Larsen, P1
Carlsson, A1
Askenazi, JJ; Rabey, JM; Streifler, M; Vardi, J1
Feigenson, JS; Goodell, H; Loranger, AW; McDowell, FH; Sweet, RD1
Birkmayer, W; Danielczyk, W; Neumayer, E; Riederer, P3
Campanelli, C; Campriani, S; Cozzolino, G1
Chazot, G; Confavreux, C; Maugiere, F; Schott, B1
Beal, MF; Bird, ED; Matson, WR; Milbury, P; Ogawa, T; Ryan, EA; Storey, E1
Marek, KL; McCance-Katz, EF; Price, LH1
Beal, MF; Bird, ED; Matson, WR; Milbury, P; Myers, RH; Ogawa, T; Saso, S1
Plewig, G; Reinauer, S1
Meltzer, HY; Parsa, MA; Ramirez, LF; Rohr, T1
van Praag, HM1
Fisher, H; Sandyk, R1
Dichgans, J; Scholz, E1
Leathwood, PD2
Schnaberth, G1
Birkmayer, W1
Harvey, NS1
Demling, J1
Slevin, JT; Sparks, DL1
Bermejo Pareja, F; de Yébenes, JG; Martinez-Martin, P; Muradas, V1
Hall, CD; Mozzis, CE; Prange, AJ; Weiss, EA1
Alunno, S; Campriani, S; Cozzolino, G; Giannini, R; Giombini, L1
Nistri, A1
Birkmayer, W; Neumayer, E2
Carroll, JD; Coppen, A; Metcalfe, M; Morris, JG1
Chase, TN; Murphy, DL; Pérez-Cruet, J1
Garelis, E; Lal, S; Sourkes, TL; Young, SN1
Shibasaki, H1
Shibazaki, H1
Matussek, N1
Presthus, J1
Brossi, A; Teitel, S1
Ahmed, R; Chow, R; Dowson, JH; Gillingham, FJ; Pullar, IA2
Curzon, G; Gumpert, J; Sharpe, D1
Fodor, A; Karczag, I; Molnár, G; Szilágyi, A; Ujvárosi, I1
Barbeau, A1
Cotzias, GC; Düby, S; Ginos, J; Papavasiliou, PS; Steck, A1
Hall, CD; Morris, CE; Prange, AJ; Weiss, EA1
Arushanian, EB; Stoliarov, GV; Tolpyshev, BA1
Sakharova, AV; Stepanova, VG1
Cooksey, B; Loncin, M; O'Reilly, S1

Reviews

25 review(s) available for tryptophan and Parkinson Disease

ArticleYear
Can kynurenine pathway be considered as a next-generation therapeutic target for Parkinson's disease? An update information.
    Bioscience trends, 2022, Sep-17, Volume: 16, Issue:4

    Topics: 3-Hydroxyanthranilic Acid; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Levodopa; Parkinson Disease; Quinolinic Acid; Tryptophan

2022
Dynamic changes in metabolites of the kynurenine pathway in Alzheimer's disease, Parkinson's disease, and Huntington's disease: A systematic Review and meta-analysis.
    Frontiers in immunology, 2022, Volume: 13

    Topics: 3-Hydroxyanthranilic Acid; Adenosine; Alzheimer Disease; Humans; Huntington Disease; Hydroxyindoleacetic Acid; Kynurenic Acid; Kynurenine; NAD; Niacinamide; Parkinson Disease; Tryptophan

2022
Exploring the Etiological Links behind Neurodegenerative Diseases: Inflammatory Cytokines and Bioactive Kynurenines.
    International journal of molecular sciences, 2020, Mar-31, Volume: 21, Issue:7

    Topics: Alzheimer Disease; Anti-Inflammatory Agents; Biomarkers; Cytokines; Humans; Huntington Disease; Inflammation; Kynurenine; Neurodegenerative Diseases; Parkinson Disease; Reactive Oxygen Species; Tryptophan

2020
TRYCAT pathways link peripheral inflammation, nicotine, somatization and depression in the etiology and course of Parkinson's disease.
    CNS & neurological disorders drug targets, 2014, Volume: 13, Issue:1

    Topics: Animals; Depression; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inflammation; Nicotine; Parkinson Disease; Signal Transduction; Somatoform Disorders; Tryptophan

2014
Neurodegeneration in Parkinson's disease: interactions of oxidative stress, tryptophan catabolites and depression with mitochondria and sirtuins.
    Molecular neurobiology, 2014, Volume: 49, Issue:2

    Topics: Animals; Brain; Depression; Humans; Lipid Peroxidation; Mitochondria; Nerve Degeneration; Oxidative Stress; Parkinson Disease; Sirtuins; Tryptophan

2014
Indoleamine 2,3 Dioxygenase as a Potential Therapeutic Target in Huntington's Disease.
    Journal of Huntington's disease, 2015, Volume: 4, Issue:2

    Topics: Alzheimer Disease; Animals; Humans; Huntington Disease; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Parkinson Disease; Signal Transduction; Tryptophan

2015
Gut Permeability and Microbiota in Parkinson's Disease: Role of Depression, Tryptophan Catabolites, Oxidative and Nitrosative Stress and Melatonergic Pathways.
    Current pharmaceutical design, 2016, Volume: 22, Issue:40

    Topics: Depression; Gastrointestinal Microbiome; Humans; Inflammation; Intestinal Mucosa; Intestines; Melatonin; Nitrosative Stress; Oxidation-Reduction; Parkinson Disease; Permeability; Tryptophan

2016
The Microbiome-Gut-Brain Axis in Health and Disease.
    Gastroenterology clinics of North America, 2017, Volume: 46, Issue:1

    Topics: Animals; Autistic Disorder; Brain; Cytokines; Depression; Fatty Acids, Volatile; gamma-Aminobutyric Acid; Gastrointestinal Microbiome; Gastrointestinal Tract; Humans; Irritable Bowel Syndrome; Parkinson Disease; Prebiotics; Probiotics; Tryptophan; Vagus Nerve

2017
Altered tryptophan metabolism in Parkinson's disease: a possible novel therapeutic approach.
    Journal of the neurological sciences, 2011, Nov-15, Volume: 310, Issue:1-2

    Topics: Antiparkinson Agents; Humans; Kynurenine; Levodopa; Parkinson Disease; Tryptophan

2011
The kynurenine pathway in neurodegenerative diseases: mechanistic and therapeutic considerations.
    Journal of the neurological sciences, 2012, Dec-15, Volume: 323, Issue:1-2

    Topics: Aging; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Animals; Enzyme Inhibitors; Humans; Huntington Disease; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inflammation; Kynurenic Acid; Kynurenine; Microglia; Molecular Targeted Therapy; Neurodegenerative Diseases; Neurons; Neuroprotective Agents; Neurotoxins; Parkinson Disease; Quinolinic Acid; Receptors, G-Protein-Coupled; Receptors, N-Methyl-D-Aspartate; Tryptophan

2012
Misincorporation of amino acid analogues into proteins by biosynthesis.
    The international journal of biochemistry & cell biology, 2008, Volume: 40, Issue:8

    Topics: Amino Acids; Amino Acids, Diamino; Aminoacylation; Animals; Bacteria; Canavanine; Ethionine; Humans; Levodopa; Lupus Erythematosus, Systemic; Oxidation-Reduction; Parkinson Disease; Plants; Protein Biosynthesis; Tryptophan

2008
Effects of foods and nutrients on brain neurotransmitters.
    Current concepts in nutrition, 1984, Volume: 13

    Topics: Amino Acids; Animals; Biological Transport, Active; Brain; Choline; Dopamine; Humans; Kinetics; Neurons; Neurotransmitter Agents; Norepinephrine; Nutritional Physiological Phenomena; Parkinson Disease; Prolactin; Serotonin; Tryptophan; Tyrosine

1984
Monoamine precursors and analogues.
    Pharmacology & therapeutics. Part B: General & systematic pharmacology, 1975, Volume: 1, Issue:3

    Topics: 5-Hydroxytryptophan; Animals; Biogenic Amines; Dihydroxyphenylalanine; Dopamine beta-Hydroxylase; Drug Interactions; Drug Synergism; Humans; Levodopa; Mice; Parkinson Disease; Rats; Receptors, Drug; Stimulation, Chemical; Tremor; Tryptophan; Tyrosine

1975
Affective disorders and aggression disorders: evidence for a common biological mechanism.
    Suicide & life-threatening behavior, 1986,Summer, Volume: 16, Issue:2

    Topics: 5-Hydroxytryptophan; Aggression; Blood Platelets; Carrier Proteins; Celiac Disease; Depressive Disorder; Female; Humans; Hydrocortisone; Hydroxyindoleacetic Acid; Male; Parkinson Disease; Prolactin; Receptors, Drug; Receptors, Neurotransmitter; Receptors, Serotonin; Serotonin; Suicide; Tryptophan

1986
Neurotransmitter precursors: from animal experiments to human applications.
    Nutrition reviews, 1986, Volume: 44 Suppl

    Topics: Alzheimer Disease; Animals; Behavior, Animal; Brain; Humans; Neurotransmitter Agents; Parkinson Disease; Protein Precursors; Sleep Stages; Tryptophan

1986
Psychiatric disorders in parkinsonism. 1. Functional illnesses and personality.
    Psychosomatics, 1986, Volume: 27, Issue:2

    Topics: Antidepressive Agents; Clozapine; Depressive Disorder; Dopamine; Electroconvulsive Therapy; Female; Homovanillic Acid; Humans; Levodopa; Male; Mental Disorders; Nomifensine; Nortriptyline; Parkinson Disease; Personality; Psychotic Disorders; Serotonin; Tryptophan

1986
[Modern treatment of parkinsonism].
    Zeitschrift fur Neurologie, 1972, Volume: 202, Issue:4

    Topics: Antiparkinson Agents; Brain Stem; Dihydroxyphenylalanine; Dopamine; Drug Synergism; Female; Gastrointestinal Diseases; Humans; Hydrazines; Hydroxyindoleacetic Acid; Male; Movement Disorders; Norepinephrine; Parkinson Disease; Psychoses, Substance-Induced; Serotonin; Tryptophan

1972
Monoamine metabolites in lumbar CSF: the question of their origin in relation to clinical studies.
    Brain research, 1974, Oct-11, Volume: 79, Issue:1

    Topics: Animals; Biological Transport, Active; Brain; Cats; Cerebral Ventricles; Cerebrospinal Fluid; Choroid Plexus; Dihydroxyphenylalanine; Dogs; Dopamine; Fenclonine; Glycols; Haplorhini; Homovanillic Acid; Humans; Hydrocephalus; Hydroxyindoleacetic Acid; Levodopa; Methoxyhydroxyphenylglycol; Parkinson Disease; Phenylacetates; Probenecid; Serotonin; Spinal Cord; Spinal Cord Injuries; Tryptophan

1974
Parkinson's syndrome. Recent progress in the medical treatment and its pharmacological basis.
    Minnesota medicine, 1971, Volume: 54, Issue:10

    Topics: Amantadine; Atropine; Catecholamines; Dihydroxyphenylalanine; Histamine H1 Antagonists; Humans; Imipramine; Parkinson Disease; Tryptophan

1971
[Recent advances and pharmacological basis of the medical treatment of Parkinson's syndrome].
    Shinkei kenkyu no shimpo. Advances in neurological sciences, 1971, Volume: 15, Issue:4

    Topics: Amantadine; Catecholamines; Dihydroxyphenylalanine; Histamine H1 Antagonists; Humans; Imipramine; Parasympatholytics; Parkinson Disease; Tryptophan

1971
[Biochemistry of depression].
    Journal of neural transmission, 1972, Volume: 33, Issue:3

    Topics: Animals; Bipolar Disorder; Brain; Central Nervous System; Depression; Dihydroxyphenylalanine; Glycols; Humans; Hydroxyindoleacetic Acid; Norepinephrine; Parkinson Disease; Peripheral Nerves; Phenylacetates; Serotonin; Tryptophan; Tryptophan Hydroxylase

1972
[Other trials with drug therapy in parkinsonism].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1973, Oct-10, Volume: 93, Issue:28

    Topics: 5-Hydroxytryptophan; Amitriptyline; Animals; Dihydroxyphenylalanine; Disulfiram; Drug Evaluation; Drug Therapy, Combination; Humans; Imipramine; Methyldopa; Monoamine Oxidase Inhibitors; Parkinson Disease; Picolinic Acids; Rats; Serine; Time Factors; Tryptophan; Tyrosine

1973
Alkaloids in the mammalian system.
    Lloydia, 1974, Volume: 37, Issue:2

    Topics: 5-Hydroxytryptophan; Acetaldehyde; Alkaloids; Animals; Aporphines; Biogenic Amines; Catalysis; Cells, Cultured; Circular Dichroism; Cyclization; Dealkylation; Dihydroxyphenylalanine; Humans; Isoquinolines; Magnetic Resonance Spectroscopy; Mammals; Methylation; Molecular Conformation; Parkinson Disease; Stereoisomerism; Tryptophan

1974
Dopamine and dopamine metabolites in Parkinson's disease-a review.
    Proceedings of the Australian Association of Neurologists, 1968, Volume: 5, Issue:1

    Topics: Brain Chemistry; Dopamine; Humans; Movement Disorders; Parkinson Disease; Phenylacetates; Tryptophan; Tyrosine

1968
Metabolic modification of Parkinson's disease and of chronic manganese poisoning.
    Annual review of medicine, 1971, Volume: 22

    Topics: Animals; Brain; Choline; Chronic Disease; Dihydroxyphenylalanine; Drug Synergism; Humans; Manganese Poisoning; Melatonin; Methionine; Monoamine Oxidase Inhibitors; Parkinson Disease; Phenylalanine; Poisoning; Pyridoxine; Tryptophan; Tyrosine

1971

Trials

9 trial(s) available for tryptophan and Parkinson Disease

ArticleYear
Effects of acute tryptophan depletion on neuropsychological and motor function in Parkinson's disease.
    Journal of psychopharmacology (Oxford, England), 2010, Volume: 24, Issue:10

    Topics: Aged; Aged, 80 and over; Cognition; Cross-Over Studies; Deficiency Diseases; Double-Blind Method; Female; Humans; Male; Memory, Short-Term; Middle Aged; Movement Disorders; Neuropsychological Tests; Parkinson Disease; Psychomotor Performance; Reaction Time; Serotonin; Severity of Illness Index; Tryptophan

2010
The effects of acute tryptophan depletion on mood in patients with Parkinson's disease and the healthy elderly.
    Journal of psychopharmacology (Oxford, England), 2010, Volume: 24, Issue:4

    Topics: Affect; Age Factors; Aged; Antiparkinson Agents; Cross-Over Studies; Depression; Double-Blind Method; Humans; Middle Aged; Parkinson Disease; Placebo Effect; Psychiatric Status Rating Scales; Serotonin; Severity of Illness Index; Tryptophan

2010
Dynamic, adaptive changes in MAO-A binding after alterations in substrate availability: an in vivo [(11)C]-harmine positron emission tomography study.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2012, Volume: 32, Issue:3

    Topics: Carbidopa; Carbon Radioisotopes; Corpus Striatum; Dopamine; Dopamine Agonists; Drug Combinations; Harmine; Humans; Levodopa; Monoamine Oxidase; Parkinson Disease; Positron-Emission Tomography; Prefrontal Cortex; Protein Binding; Serotonin; Substrate Specificity; Time Factors; Tryptophan

2012
Hypothalamic digoxin-mediated model for Parkinson's disease.
    The International journal of neuroscience, 2003, Volume: 113, Issue:4

    Topics: Aged; Digoxin; Dolichols; Enzyme Inhibitors; Erythrocytes; Female; Glycoconjugates; Glycosaminoglycans; Humans; Hydroxymethylglutaryl CoA Reductases; Hypothalamus; Male; Membrane Proteins; Middle Aged; Models, Biological; Neurons; Parkinson Disease; Polyisoprenyl Phosphates; Sodium-Potassium-Exchanging ATPase; Tryptophan; Tyrosine; Ubiquinone

2003
The serotonergic hypothesis for depression in Parkinson's disease: an experimental approach.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2006, Volume: 31, Issue:5

    Topics: Affect; Aged; Brain; Causality; Cross-Over Studies; Depressive Disorder; Double-Blind Method; Female; Food, Formulated; Humans; Male; Middle Aged; Neuropsychological Tests; Parkinson Disease; Serotonin; Surveys and Questionnaires; Synaptic Transmission; Tryptophan

2006
Effects of acute tryptophan depletion on cognition, memory and motor performance in Parkinson's disease.
    Journal of the neurological sciences, 2006, Oct-25, Volume: 248, Issue:1-2

    Topics: Aged; Amino Acids; Cognition; Cross-Over Studies; Double-Blind Method; Female; Humans; Male; Memory; Middle Aged; Neuropsychological Tests; Parkinson Disease; Psychomotor Performance; Reaction Time; Severity of Illness Index; Tryptophan

2006
L-tryptophan in the treatment of levodopa induced psychiatric disorders.
    Diseases of the nervous system, 1974, Volume: 35, Issue:1

    Topics: Aged; Aged, 80 and over; Antiparkinson Agents; Brain; Female; Humans; Levodopa; Male; Mental Disorders; Middle Aged; Parkinson Disease; Serotonin; Single-Blind Method; Treatment Outcome; Tryptophan

1974
Mental symptoms in Parkinson's disease during chronic treatment with levodopa.
    Neurology, 1976, Volume: 26, Issue:4

    Topics: Adult; Aged; Delirium; Dementia; Female; Humans; Levodopa; Male; Mental Disorders; Middle Aged; Parkinson Disease; Parkinson Disease, Postencephalitic; Tryptophan

1976
Levodopa and L-tryptophan therapy in Parkinsonism.
    Lancet (London, England), 1972, Mar-25, Volume: 1, Issue:7752

    Topics: Aged; Depression; Dihydroxyphenylalanine; Female; Gait; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Nausea; Occupational Therapy; Parkinson Disease; Personality Inventory; Physical Therapy Modalities; Posture; Psychiatric Status Rating Scales; Spasm; Speech Therapy; Tremor; Tryptophan

1972

Other Studies

71 other study(ies) available for tryptophan and Parkinson Disease

ArticleYear
Tryptophan 2,3-dioxygenase, a novel therapeutic target for Parkinson's disease.
    Expert opinion on therapeutic targets, 2021, Volume: 25, Issue:10

    Topics: Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Parkinson Disease; Tryptophan; Tryptophan Oxygenase

2021
Imaging of cerebral tryptophan metabolism using 7-[
    NeuroImage, 2022, 02-15, Volume: 247

    Topics: Animals; Disease Models, Animal; Fluorine Radioisotopes; Hippocampus; Kynurenine; Male; Melatonin; Oxidopamine; Parkinson Disease; Pineal Gland; Positron-Emission Tomography; Radiopharmaceuticals; Rats; Rats, Long-Evans; Serotonin; Tryptophan

2022
Exposure to the environmentally toxic pesticide maneb induces Parkinson's disease-like neurotoxicity in mice: A combined proteomic and metabolomic analysis.
    Chemosphere, 2022, Volume: 308, Issue:Pt 2

    Topics: alpha-Synuclein; Animals; Environmental Pollutants; Fungicides, Industrial; Humans; Maneb; Metabolomics; Mice; Neuroblastoma; Neurotoxicity Syndromes; Paraquat; Parkinson Disease; Pesticides; Phenylalanine; Proteomics; Tryptophan

2022
Single Nucleotide Polymorphisms of Indoleamine 2,3-Dioxygenase 1 Influenced the Age Onset of Parkinson's Disease.
    Frontiers in bioscience (Landmark edition), 2022, 09-27, Volume: 27, Issue:9

    Topics: Biomarkers; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Parkinson Disease; Polymorphism, Single Nucleotide; Tryptophan

2022
Faecal metabolite deficit, gut inflammation and diet in Parkinson's disease: Integrative analysis indicates inflammatory response syndrome.
    Clinical and translational medicine, 2023, Volume: 13, Issue:1

    Topics: Benzoates; Diet; Humans; Inflammation; Leukocyte L1 Antigen Complex; Maltose; Parkinson Disease; Tryptophan

2023
Tryptophan Metabolites Are Associated With Symptoms and Nigral Pathology in Parkinson's Disease.
    Movement disorders : official journal of the Movement Disorder Society, 2020, Volume: 35, Issue:11

    Topics: Biomarkers; Humans; Kynurenine; Parkinson Disease; Substantia Nigra; Tryptophan

2020
Tryptophan in the diet ameliorates motor deficits in a rotenone-induced rat Parkinson's disease model via activating the aromatic hydrocarbon receptor pathway.
    Brain and behavior, 2021, Volume: 11, Issue:8

    Topics: Animals; Diet; Disease Models, Animal; Hydrocarbons, Aromatic; Neuroprotective Agents; Parkinson Disease; Rats; Rotenone; Tryptophan

2021
A novel Parkinson's disease risk variant, p. W378R, in the Gaucher's disease GBA gene.
    Movement disorders : official journal of the Movement Disorder Society, 2018, Volume: 33, Issue:10

    Topics: Adult; Aged; Arginine; Family Health; Female; Gaucher Disease; Glucosylceramidase; Humans; Male; Middle Aged; Mutation; Parkinson Disease; Tryptophan

2018
Membrane bound α-synuclein is fully embedded in the lipid bilayer while segments with higher flexibility remain.
    FEBS letters, 2013, Aug-19, Volume: 587, Issue:16

    Topics: Acrylamide; alpha-Synuclein; Amino Acid Sequence; Cell Membrane; Humans; Lipid Bilayers; Lipids; Micelles; Molecular Sequence Data; Parkinson Disease; Phosphatidylcholines; Phosphatidylserines; Protein Binding; Protein Structure, Tertiary; Tryptophan

2013
Effects of L-tryptophan on L-DOPA-induced dyskinesia in the L-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated macaque model of Parkinson's disease.
    Neuroscience letters, 2014, Apr-30, Volume: 566

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Antiparkinson Agents; Corpus Striatum; Dopamine; Dyskinesia, Drug-Induced; Female; Levodopa; Macaca fascicularis; Motor Activity; Parkinson Disease; Tryptophan

2014
NMDA antagonists as Parkinson's disease therapy: disseminating the evidence.
    Neurodegenerative disease management, 2014, Volume: 4, Issue:1

    Topics: Animals; Antiparkinson Agents; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Parkinson Disease; Receptors, N-Methyl-D-Aspartate; Tryptophan

2014
LC-MS-based urinary metabolite signatures in idiopathic Parkinson's disease.
    Journal of proteome research, 2015, Jan-02, Volume: 14, Issue:1

    Topics: alpha-Synuclein; Animals; Biomarkers; Chromatography, Liquid; Drosophila melanogaster; Fatty Acids; Histidine; Humans; Kynurenine; Mass Spectrometry; Metabolomics; Nucleotides; Parkinson Disease; Phenotype; Phenylalanine; Steroids; Tryptophan; Tyrosine

2015
Structural features of membrane-bound glucocerebrosidase and α-synuclein probed by neutron reflectometry and fluorescence spectroscopy.
    The Journal of biological chemistry, 2015, Jan-09, Volume: 290, Issue:2

    Topics: alpha-Synuclein; Gaucher Disease; Glucosylceramidase; Humans; Lipid Bilayers; Mutation; Neutron Diffraction; Parkinson Disease; Protein Binding; Spectrometry, Fluorescence; Surface Plasmon Resonance; Tryptophan

2015
A tripeptide isolated from Bothrops atrox venom has neuroprotective and neurotrophic effects on a cellular model of Parkinson's disease.
    Chemico-biological interactions, 2015, Jun-25, Volume: 235

    Topics: 1-Methyl-4-phenylpyridinium; Animals; Apoptosis; Bothrops; Caspase 3; Caspase 9; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dopamine; Dopaminergic Neurons; Glutamic Acid; Mitochondria; Models, Biological; Neuroprotective Agents; Parkinson Disease; PC12 Cells; Peptides; Rats; Tryptophan; Valine; Venoms

2015
Dynamic DNA Methylation Regulates Levodopa-Induced Dyskinesia.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2016, 06-15, Volume: 36, Issue:24

    Topics: Analysis of Variance; Animals; Antiparkinson Agents; Corpus Striatum; Dioxygenases; Disease Models, Animal; DNA Methylation; Dopamine; Dyskinesia, Drug-Induced; Enzyme Inhibitors; GADD45 Proteins; Gene Expression Regulation; Immunoprecipitation; Intracellular Signaling Peptides and Proteins; Levodopa; Male; Medial Forebrain Bundle; Oxidopamine; Parkinson Disease; Parkinson Disease, Secondary; Phthalimides; Rats; Rats, Sprague-Dawley; Tryptophan

2016
Is Ro 61-8048 a potential fast-acting antidepressant?
    Journal of the neurological sciences, 2012, Apr-15, Volume: 315, Issue:1-2

    Topics: Humans; Parkinson Disease; Tryptophan

2012
Mutation of the PDGFRB gene as a cause of idiopathic basal ganglia calcification.
    Neurology, 2013, Jan-08, Volume: 80, Issue:2

    Topics: Adult; Aged; Amino Acid Substitution; Arginine; Basal Ganglia Diseases; Calcinosis; Child; Databases, Genetic; Exome; Female; Humans; Leucine; Magnetic Resonance Imaging; Male; Middle Aged; Mutation; Neurologic Examination; Parkinson Disease; Pedigree; Polymerase Chain Reaction; Proline; Receptor, Platelet-Derived Growth Factor beta; Tomography, X-Ray Computed; Tryptophan

2013
Oxidative damage and cytogenic analysis in leukocytes of Parkinson's disease patients.
    Neurology, 2003, Feb-25, Volume: 60, Issue:4

    Topics: Cytogenetic Analysis; Homocysteine; Humans; Inflammation; Interferon-gamma; Leukocytes; Macrophages; Neopterin; Oxidative Stress; Parkinson Disease; T-Lymphocytes; Tryptophan

2003
Characterization of oligomeric intermediates in alpha-synuclein fibrillation: FRET studies of Y125W/Y133F/Y136F alpha-synuclein.
    Journal of molecular biology, 2005, Oct-21, Volume: 353, Issue:2

    Topics: alpha-Synuclein; Anilino Naphthalenesulfonates; Benzothiazoles; Fluorescence Resonance Energy Transfer; Fluorescent Dyes; Humans; Mutagenesis, Site-Directed; Nerve Tissue Proteins; Parkinson Disease; Protein Structure, Secondary; Spectroscopy, Fourier Transform Infrared; Synucleins; Thiazoles; Tryptophan; Tyrosine

2005
Monoamine metabolites in human cerebrospinal fluid. HPLC/ED method.
    Acta neurologica Scandinavica, 1984, Volume: 69, Issue:4

    Topics: 3,4-Dihydroxyphenylacetic Acid; Alzheimer Disease; Chromatography, High Pressure Liquid; Depression; Dihydroxyphenylalanine; Electrochemistry; Glycols; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Methoxyhydroxyphenylglycol; Parkinson Disease; Phenylacetates; Subarachnoid Hemorrhage; Tryptophan; Tyrosine

1984
Pyridoxal phosphate, tryptophan, and tyrosine in blood and cerebrospinal fluid in elderly patients.
    Upsala journal of medical sciences, 1984, Volume: 89, Issue:3

    Topics: Adult; Age Factors; Aged; Humans; Hydrocephalus; Middle Aged; Parkinson Disease; Pyridoxal Phosphate; Tryptophan; Tyrosine

1984
The effect of carbidopa and benserazide on human plasma 5-hydroxytryptophan levels.
    Journal of neural transmission, 1982, Volume: 53, Issue:1

    Topics: 5-Hydroxytryptophan; Adult; Benserazide; Carbidopa; Chlorpromazine; Dihydroxyphenylalanine; Humans; Hydrazines; Middle Aged; Parkinson Disease; Schizophrenia; Tryptophan

1982
Tryptophan deficiency stupor--a new psychiatric syndrome.
    Acta psychiatrica Scandinavica. Supplementum, 1982, Volume: 300

    Topics: Aged; Animals; Carcinoid Tumor; Female; Humans; Levodopa; Malabsorption Syndromes; Male; Mental Disorders; Middle Aged; Muscles; Parkinson Disease; Serotonin; Syndrome; Tryptophan

1982
L-dopa competes with tyrosine and tryptophan for human brain uptake.
    Nutrition and metabolism, 1980, Volume: 24, Issue:6

    Topics: Aged; Benserazide; Blood-Brain Barrier; Brain; Female; Humans; Levodopa; Male; Parkinson Disease; Tryptophan; Tyrosine

1980
Treatment with tryptophan of levodopa-associated psychiatric disturbances.
    Archives of neurology, 1980, Volume: 37, Issue:3

    Topics: Aged; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Psychiatric Status Rating Scales; Psychoses, Substance-Induced; Tryptophan

1980
Duration of illness and response to tryptophan in Parkinson's disease.
    Archives of neurology, 1980, Volume: 37, Issue:10

    Topics: Dreams; Female; Humans; Male; Parkinson Disease; Psychiatric Status Rating Scales; Tryptophan

1980
Concentrations of serotonin and its related substances in the cerebrospinal fluid of parkinsonian patients and their relations to the severity of symptoms.
    Neuroscience letters, 1993, Feb-05, Volume: 150, Issue:1

    Topics: 5-Hydroxytryptophan; Humans; Hydroxyindoleacetic Acid; Kynurenine; Middle Aged; Parkinson Disease; Reference Values; Serotonin; Tryptophan

1993
Serotonin and Parkinson's disease.
    The American journal of psychiatry, 1993, Volume: 150, Issue:5

    Topics: Basal Ganglia Diseases; Depressive Disorder; Dopamine; Drug Therapy, Combination; Fluoxetine; Humans; Levodopa; Parkinson Disease; Serotonin; Tryptophan

1993
Endogenous alkaloids in the brain of rats loaded with tyrosine/tryptophan & in the serum of patients of neurodegenerative & psychiatric disorders.
    The Indian journal of medical research, 1998, Volume: 107

    Topics: Alkaloids; Animals; Bipolar Disorder; Brain; Chromatography, High Pressure Liquid; Epilepsy; Female; Humans; Parkinson Disease; Rats; Rats, Sprague-Dawley; Tryptophan; Tyrosine

1998
Tryptophan and tyrosine catabolic pattern in neuropsychiatric disorders.
    Neurology India, 2000, Volume: 48, Issue:3

    Topics: Adult; Biogenic Monoamines; Brain Diseases; Brain Neoplasms; Digoxin; Epilepsy, Generalized; Erythrocytes; Fatty Acids, Nonesterified; Female; Glioma; Glycine Agents; Humans; Hydroxymethylglutaryl CoA Reductases; Kynurenic Acid; Magnesium; Male; Microvascular Angina; Middle Aged; Morphine; Narcotics; Nicotine; Nicotinic Agonists; Parkinson Disease; Quinolinic Acid; Schizophrenia; Serum Albumin; Sodium-Potassium-Exchanging ATPase; Strychnine; Tryptophan; Tyrosine; Ubiquinone

2000
Increased neopterin production and tryptophan degradation in advanced Parkinson's disease.
    Journal of neural transmission (Vienna, Austria : 1996), 2002, Volume: 109, Issue:2

    Topics: Aged; Chromatography, High Pressure Liquid; Female; Humans; Immunity, Cellular; Kynurenine; Male; Neopterin; Parkinson Disease; Tryptophan

2002
Letter: Do changes in blood levels of other aromatic aminoacids influence levodopa therapy?
    Lancet (London, England), 1976, Jan-10, Volume: 1, Issue:7950

    Topics: Amino Acids; Blood-Brain Barrier; Histidine; Humans; Levodopa; Parkinson Disease; Phenylalanine; Tryptophan

1976
[Psychopharmacology of tryptophan (author's transl)].
    Pathologie-biologie, 1977, Volume: 25, Issue:8

    Topics: Animals; Bipolar Disorder; Depression; Humans; Mental Disorders; Parkinson Disease; Schizophrenia; Serotonin; Sleep; Tryptophan

1977
Niacin depletion in Parkinsonian patients treated with L-dopa, benserazide and carbidopa.
    Clinical science (London, England : 1979), 1979, Volume: 56, Issue:1

    Topics: Adolescent; Adult; Benserazide; Bromocriptine; Carbidopa; Female; Humans; Hydrazines; Levodopa; Male; Micrococcus; Middle Aged; Nicotinamidase; Nicotinic Acids; Parkinson Disease; Tryptophan

1979
Untreated acrodermatitis enteropathica in adults.
    Dermatologica, 1978, Volume: 156, Issue:3

    Topics: Acrodermatitis; Adult; Age Factors; Female; Humans; Malabsorption Syndromes; Male; Parkinson Disease; Paronychia; Syndrome; Tryptophan; Zinc

1978
L-tryptophan administration in L-dopa-induced hallucinations in elderly Parkinsonian patients.
    Gerontology, 1977, Volume: 23, Issue:6

    Topics: Aged; Female; Hallucinations; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Tryptophan

1977
Dopaminergic supersensitivity in parkinsonism.
    Advances in neurology, 1975, Volume: 9

    Topics: Aged; Benzyl Compounds; Brain; Brain Chemistry; Dopamine; Drug Therapy, Combination; Female; Humans; Hydrazines; Hydroxyindoleacetic Acid; Levodopa; Nerve Degeneration; Norepinephrine; Parkinson Disease; Psychoses, Substance-Induced; Serotonin; Tryptophan; Tyrosine

1975
Tryptophan/nicotinic acid pathway during levodopa treatment of Parkinsonism.
    Acta vitaminologica et enzymologica, 1975, Volume: 29, Issue:1-6

    Topics: Adult; Aged; Female; Humans; Levodopa; Male; Middle Aged; Nicotinic Acids; Parkinson Disease; Tryptophan

1975
[Letter: Effectiveness of L-tryptophan on Parkinsonian tremor. Preliminary study].
    La Nouvelle presse medicale, 1976, Jan-31, Volume: 5, Issue:5

    Topics: Adult; Aged; Drug Evaluation; Female; Humans; Male; Middle Aged; Parkinson Disease; Tryptophan

1976
Kynurenic acid concentrations are reduced in Huntington's disease cerebral cortex.
    Journal of the neurological sciences, 1992, Volume: 108, Issue:1

    Topics: Aged; Alzheimer Disease; Cerebral Cortex; Energy Metabolism; Free Radicals; Humans; Huntington Disease; Kynurenic Acid; Kynurenine; Middle Aged; Parkinson Disease; Purines; Tryptophan; Tyrosine

1992
Serotonergic dysfunction in depression associated with Parkinson's disease.
    Neurology, 1992, Volume: 42, Issue:9

    Topics: Depressive Disorder; Fluvoxamine; Humans; Male; Middle Aged; Neurotransmitter Uptake Inhibitors; Parkinson Disease; Serotonin; Tryptophan

1992
Kynurenine pathway abnormalities in Parkinson's disease.
    Neurology, 1992, Volume: 42, Issue:9

    Topics: Aged; Autopsy; Brain; Female; Humans; Kynurenine; Male; Parkinson Disease; Tryptophan; Tyrosine

1992
[Eosinophilia-myalgia syndrome].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1991, Volume: 42, Issue:3

    Topics: Aged; Biopsy; Electromyography; Eosinophilia; Female; Humans; Middle Aged; Muscles; Neuromuscular Diseases; Parkinson Disease; Scleroderma, Systemic; Skin; Sleep Initiation and Maintenance Disorders; Syndrome; Tryptophan

1991
Neuroleptic malignant syndrome without neuroleptics.
    Journal of clinical psychopharmacology, 1990, Volume: 10, Issue:6

    Topics: Aged; Aged, 80 and over; Antiparkinson Agents; Carbidopa; Depressive Disorder; Drug Combinations; Drug Therapy, Combination; Female; Humans; Levodopa; Neuroleptic Malignant Syndrome; Parkinson Disease; Substance Withdrawal Syndrome; Tranylcypromine; Tryptophan

1990
L-tryptophan supplementation in Parkinson's disease.
    The International journal of neuroscience, 1989, Volume: 45, Issue:3-4

    Topics: Aged; Drug Therapy, Combination; Female; Humans; Levodopa; Middle Aged; Parkinson Disease; Tryptophan

1989
Treatment of drug-induced exogenous psychosis in parkinsonism with clozapine and fluperlapine.
    European archives of psychiatry and neurological sciences, 1985, Volume: 235, Issue:1

    Topics: Aged; Antipsychotic Agents; Benserazide; Bromocriptine; Clozapine; Delusions; Dibenzazepines; Dose-Response Relationship, Drug; Drug Therapy, Combination; Hallucinations; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease; Psychoses, Substance-Induced; Tryptophan

1985
Neurotransmitter precursors and brain function.
    Bibliotheca nutritio et dieta, 1986, Issue:38

    Topics: Aged; Aging; Alzheimer Disease; Animals; Biological Transport; Brain; Diet; Humans; Learning; Levodopa; Memory; Neurotransmitter Agents; Parkinson Disease; Phosphatidylcholines; Serotonin; Sleep; Tryptophan

1986
[Depression and Parkinson syndrome].
    Wiener medizinische Wochenschrift (1946), 1986, Aug-31, Volume: 136, Issue:15-16

    Topics: Antidepressive Agents; Brain; Depressive Disorder; Drug Therapy, Combination; Humans; Levodopa; Neurotransmitter Agents; Parkinson Disease; Tryptophan

1986
Milestones in the development of modern Parkinson therapy.
    Journal of neural transmission. Supplementum, 1987, Volume: 25

    Topics: 2,3-Diketogulonic Acid; Alloxan; Behavior; Bromocriptine; Drug Combinations; Drug Therapy, Combination; Ferric Compounds; Humans; Levodopa; Neurology; Parkinson Disease; Selegiline; Tryptophan

1987
[L-dopa-induced psychoses and their treatment with L-tryptophan].
    Fortschritte der Medizin, 1986, Apr-30, Volume: 104, Issue:17

    Topics: Humans; Levodopa; Parkinson Disease; Psychoses, Substance-Induced; Tryptophan

1986
Determination of tyrosine, tryptophan and their metabolic derivatives by liquid chromatography-electrochemical detection: application to post mortem samples from patients with Parkinson's and Alzheimer's disease.
    Life sciences, 1985, Feb-04, Volume: 36, Issue:5

    Topics: Aged; Alzheimer Disease; Animals; Chromatography, High Pressure Liquid; Electrochemistry; Female; Humans; Male; Middle Aged; Parkinson Disease; Rats; Tryptophan; Tyrosine

1985
Carbidopa dosage modifies L-dopa induced side effects and blood levels of L-dopa and other amino acids in advanced parkinsonism.
    Acta neurologica Scandinavica, 1985, Volume: 72, Issue:5

    Topics: Aged; Carbidopa; Drug Therapy, Combination; Female; Homovanillic Acid; Humans; Kinetics; Levodopa; Male; Middle Aged; Parkinson Disease; Tryptophan; Tyrosine

1985
Levodopa and depression in parkinsonism.
    Lancet (London, England), 1971, Jan-16, Volume: 1, Issue:7690

    Topics: Depression; Dihydroxyphenylalanine; Drug Synergism; Humans; Parkinson Disease; Tryptophan

1971
Inefficacy of tryptophan-pyridoxine in essential tremor.
    Lancet (London, England), 1971, Jul-17, Volume: 2, Issue:7716

    Topics: Basal Ganglia; Dihydroxyphenylalanine; Drug Synergism; Female; Humans; Male; Parkinson Disease; Pyridoxine; Tremor; Tryptophan

1971
Tryptophan nicotinic-acid metabolism during levodopa treatment of parkinsonism.
    Lancet (London, England), 1971, Volume: 2, Issue:7732

    Topics: Dihydroxyphenylalanine; Humans; Male; Middle Aged; Nicotinic Acids; Parkinson Disease; Tryptophan

1971
Levodopa and L-tryptophan in parkinsonism.
    Lancet (London, England), 1972, Apr-22, Volume: 1, Issue:7756

    Topics: Brain; Dihydroxyphenylalanine; Drug Synergism; Humans; Parkinson Disease; Tryptophan

1972
Dietary regulation of brain tryptophan metabolism by plasma ratio of free tryptophan and neutral amino acids in humans.
    Nature, 1974, Apr-19, Volume: 248, Issue:5450

    Topics: Amino Acids; Blood Proteins; Brain; Diet; Eating; Fasting; Feeding Behavior; Humans; Huntington Disease; Hydroxyindoleacetic Acid; Parkinson Disease; Protein Binding; Tryptophan

1974
[Malignant melanoma and L-dopa. Review of literature on the problem of causal relationship].
    Fortschritte der Medizin, 1974, Sep-26, Volume: 92, Issue:27

    Topics: Humans; Levodopa; Male; Melanins; Melanoma; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Parkinson Disease; Skin Neoplasms; Tryptophan

1974
[L-tryptophan therapy of DOPA psychoses].
    Der Nervenarzt, 1972, Volume: 43, Issue:2

    Topics: Aged; Athetosis; Cardiovascular Diseases; Chorea; Constipation; Dihydroxyphenylalanine; Feeding and Eating Disorders; Female; Humans; Male; Middle Aged; Parkinson Disease; Psychoses, Substance-Induced; Seizures; Sleep Wake Disorders; Tryptophan; Vertigo; Vomiting

1972
The balance of biogenic amines as condition for normal behaviour.
    Journal of neural transmission, 1972, Volume: 33, Issue:2

    Topics: Aged; Benzyl Compounds; Brain; Dihydroxyphenylalanine; Dopamine; Electroencephalography; Female; Humans; Hydrazines; Hydroxyindoleacetic Acid; Male; Middle Aged; Norepinephrine; Parkinson Disease; Phenylacetates; Psychoses, Substance-Induced; Serine; Serotonin; Tryptophan

1972
Biochemical investigations in Parkinsonism. A study of the metabolites of the biogenic amines in the lumbar CSF.
    Confinia neurologica, 1972, Volume: 34, Issue:2

    Topics: Dihydroxyphenylalanine; Dopamine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Microscopy, Fluorescence; Parkinson Disease; Phenylacetates; Tryptophan

1972
Amine metabolites in the cerebrospinal fluid in Parkinson's disease and the response to levodopa.
    Journal of the neurological sciences, 1973, Volume: 19, Issue:1

    Topics: Adult; Aged; Dihydroxyphenylalanine; Dopamine; Dose-Response Relationship, Drug; Electroencephalography; Evaluation Studies as Topic; Female; Follow-Up Studies; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Parkinson Disease; Phenylacetates; Serotonin; Tryptophan

1973
Tryptophan malabsorption in levodopa-treated parkinsonian patients. Effect of tryptophan on mental disturbances.
    Acta medica Scandinavica, 1973, Volume: 194, Issue:3

    Topics: Aged; Brain; Dementia; Depression, Chemical; Dihydroxyphenylalanine; Female; Humans; Hydroxyindoleacetic Acid; Intestinal Absorption; Male; Mental Disorders; Middle Aged; Parkinson Disease; Serotonin; Tryptophan

1973
5-Hydroxyindoleacetic acid in cerebrospinal fluid.
    Acta medica Academiae Scientiarum Hungaricae, 1973, Volume: 30, Issue:3

    Topics: Adult; Age Factors; Brain Diseases; Brain Stem; Depression; Epilepsy; Humans; Hydroxyindoleacetic Acid; Mental Disorders; Middle Aged; Neurocognitive Disorders; Paralysis; Parkinson Disease; Probenecid; Spectrometry, Fluorescence; Spinal Cord Compression; Tabes Dorsalis; Tryptophan

1973
[Serum tryptophan in cases with senile dementia, parkinsonism and normal cases].
    Lakartidningen, 1974, Mar-27, Volume: 71, Issue:13

    Topics: Adult; Aged; Dementia; Dihydroxyphenylalanine; Female; Humans; Male; Middle Aged; Parkinson Disease; Time Factors; Tryptophan

1974
Nucleus ruber and L-dopa psychosis: biochemical post-mortem findings.
    Journal of neural transmission, 1974, Volume: 35, Issue:2

    Topics: Aged; Amygdala; Autopsy; Biogenic Amines; Caudate Nucleus; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Female; Globus Pallidus; Gyrus Cinguli; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Norepinephrine; Parkinson Disease; Psychoses, Substance-Induced; Red Nucleus; Serotonin; Substantia Nigra; Tryptophan; Tyrosine

1974
Rapid deterioration in patients with parkinsonism following tryptophan-pyridoxine administration.
    Neurology, 1972, Volume: 22, Issue:3

    Topics: Adult; Brain; Drug Synergism; Humans; Male; Middle Aged; Parkinson Disease; Pyridoxine; Reaction Time; Tryptophan

1972
Biochemical investigations in Parkinsonism. A study of the metabolites of the biogenic amines in the lumbar CSF.
    Confinia neurologica, 1972, Volume: 34, Issue:1

    Topics: Caudate Nucleus; Dihydroxyphenylalanine; Humans; Hydroxyindoleacetic Acid; Microscopy, Fluorescence; Parkinson Disease; Phenylacetates; Serotonin; Tryptophan

1972
[The effect of phenamine on medicinal parkinsonism and retardation of movement upon stimulation of the caudate nucleus (a clinico-experimental study)].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1970, Volume: 70, Issue:9

    Topics: Amphetamine; Caudate Nucleus; Female; Haloperidol; Humans; Male; Parkinson Disease; Parkinson Disease, Secondary; Schizophrenia; Tryptophan

1970
[The protein nature of specific cellular inclusions (Lewy's bodies) in Parkinson's disease].
    Arkhiv patologii, 1967, Volume: 29, Issue:9

    Topics: Acetylcholinesterase; Acid Phosphatase; Alkaline Phosphatase; Amino Acids; Cholinesterases; Cystine; Cytoplasmic Granules; Histidine; Histocytochemistry; Humans; Lipase; Lysine; Microscopy, Electron; Neurons; Parkinson Disease; Proteins; Substantia Nigra; Sulfites; Tryptophan; Tyrosine

1967
Dopamine and basal ganglia disorders.
    Neurology, 1965, Volume: 15, Issue:11

    Topics: Adult; Basal Ganglia; Dopamine; Female; Hepatolenticular Degeneration; Humans; Hydroxyindoleacetic Acid; In Vitro Techniques; Infant, Newborn; Male; Malignant Carcinoid Syndrome; Middle Aged; Movement Disorders; Parkinson Disease; Phenylalanine; Pregnancy; Serotonin; Tryptophan; Urine

1965