tryptophan has been researched along with Parkinson Disease in 105 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 59 (56.19) | 18.7374 |
1990's | 8 (7.62) | 18.2507 |
2000's | 8 (7.62) | 29.6817 |
2010's | 20 (19.05) | 24.3611 |
2020's | 10 (9.52) | 2.80 |
Authors | Studies |
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Boros, FA; Vécsei, L | 1 |
Alavinejad, N; Apetz, N; Drzezga, A; Endepols, H; Neumaier, B; Vus, S; Zischler, J; Zlatopolskiy, BD | 1 |
Asakawa, T; Chen, W; Jia, X; Qin, W; Shi, Y | 1 |
Dai, L; Du, Z; Fang, Y; Jiang, H; Li, F; Li, H; Liu, C; Liu, Z; Meng, L; Tian, Y; Wang, Z; Xiong, M; Yan, Z; Yu, T; Yuan, X; Zhang, J; Zhang, Z | 1 |
Boda, K; Klivényi, P; Maszlag-Török, R; Molnár, K; Somogyvári, F; Szolnoki, Z; Tanaka, M; Török, N; Vécsei, L | 1 |
Fathi, M; Hajibeygi, R; Jazi, K; Klegeris, A; McElhinney, A; Sayehmiri, F; Shool, S; Sodeifian, F; Tavasol, A; Tavirani, MR; Vakili, K; Yaghoobpoor, S | 1 |
Augustin, A; Balasubramanian, K; Bjarnason, I; Charlett, A; Chekmeneva, E; DeSouza, N; Dobbs, RJ; Dobbs, SM; Guennec, AL; Hayee, BH; Ibrahim, MAA; Kendler-Rhodes, A; Lewis, M; Ma, Y; Mullish, BH; Ryan, S; Takis, P; Taylor, D; Tucker, RM; Umamahesan, C; Weller, C; Whelan, K | 1 |
Tanaka, M; Toldi, J; Vécsei, L | 1 |
Brundin, L; Brundin, P; Burmeister, AR; Capan, CD; Du, G; Escobar Galvis, ML; Heilman, PL; Huang, X; Krzyzanowski, S; Lewis, MM; Wang, EW | 1 |
Chen, S; Gao, Y; Liu, Y; Tan, J; Wang, Y; Wu, H; Xiao, Z; Yan, H; Yi, S | 1 |
Blackie, J; Chu, S; Ellis, M; Hayes, M; Kennerson, M; Lubomski, M; Nicholson, G; O'Sullivan, JD | 1 |
Amoussouvi, A; Haralampiev, I; Herrmann, A; Stöckl, M; Wietek, J | 1 |
Anderson, G; Maes, M | 2 |
Bezard, E; Ko, WK; Li, Q | 1 |
Majláth, Z; Vécsei, L | 1 |
Cai, Z; Chen, LL; Chua, KK; Li, M; Liu, LF; Luan, H; Meng, N; Mok, VC; Song, JX; Tang, Z; Xie, LX | 1 |
Barros, M; Curtis, JE; Gruschus, JM; Heinrich, F; Jiang, Z; Lee, JC; Pfefferkorn, CM; Sidransky, E; Yap, TL | 1 |
Cintra, AC; Martins, NM; Sampaio, SV; Santos, AC; Santos, NA; Sartim, MA | 1 |
Leavitt, BR; Mazarei, G | 1 |
Eskow Jaunarajs, KL; Figge, DA; Standaert, DG | 1 |
Anderson, G; Berk, M; Carvalho, AF; Maes, M; Seo, M | 1 |
Cryan, JF; Dinan, TG | 1 |
Anderson, TJ; Dalrymple-Alford, JC; Mace, JL; Porter, RJ; Wesnes, KA | 1 |
Anderson, TJ; Dalrymple-Alford, JC; Mace, JL; Porter, RJ | 1 |
Kincses, ZT; Szabó, N; Toldi, J; Vécsei, L | 1 |
Li, W; Yang, C; Yang, J; Zhou, Z | 1 |
Boskovic, R; Clark, M; Houle, S; Kish, SJ; Meyer, JH; Rabiner, EA; Rusjan, P; Sacher, J; Soliman, A; Wilson, AA | 1 |
Tan, L; Yu, JT | 1 |
Augustin, J; Ayrignac, X; Campion, D; Clanet, M; Coutant, S; Defebvre, L; Frébourg, T; Guyant-Maréchal, L; Hannequin, D; Krystkowiak, P; Labauge, P; Le Ber, I; Lefaucheur, R; Legallic, S; Maltête, D; Martinaud, O; Nicolas, G; Pariente, J; Pottier, C; Rousseau, S; Rovelet-Lecrux, A; Vaschalde, Y | 1 |
Fuchs, D; Leblhuber, F; Neurauter, G | 1 |
Kurup, PA; Kurup, RK | 1 |
Bodner, N; Edridge, S; Fink, AL; Hong, DP; Kaylor, J; Yamin, G | 1 |
Leentjens, AF; Scholtissen, B; Verhey, FR; Vreeling, FW | 1 |
Adam, JJ; Leentjens, AF; Prickaerts, J; Scholtissen, B; Verhey, FR | 1 |
Miller, EM; Nieburg, HA | 1 |
Rodgers, KJ; Shiozawa, N | 1 |
Wurtman, RJ | 1 |
Aguado, EG; de Yebenes, JG; Mena, MA | 1 |
Botteri, A; Hamfelt, A; Söderhjelm, L | 1 |
Anderson, GM; Chouinard, G; Gauthier, S; Purdy, WC; Young, SN | 1 |
Lehmann, J | 4 |
Riederer, P | 1 |
Beasley, BL; Chase, TN; Davenport, RW; Nutt, JG | 1 |
Bryant, RC | 1 |
Abe, T; Hamato, H; Takahashi, J; Takahashi, S; Tohgi, H | 1 |
Hesselink, JM | 1 |
Arun, P; Kurup, PA; Leelamma, S; Ravikumar, A | 1 |
Arun, P; Deepadevi, KV; Kurup, PA; Manojkumar, V; Ravikumar, A | 1 |
Fuchs, D; Leblhuber, F; Widner, B | 1 |
Daniel, PM; Moorhouse, RS; Pratt, OE | 1 |
Boulu, R; Poitou, P | 1 |
Bender, DA; Earl, CJ; Lees, AJ | 1 |
Olholm-Larsen, P | 1 |
Carlsson, A | 1 |
Askenazi, JJ; Rabey, JM; Streifler, M; Vardi, J | 1 |
Feigenson, JS; Goodell, H; Loranger, AW; McDowell, FH; Sweet, RD | 1 |
Birkmayer, W; Danielczyk, W; Neumayer, E; Riederer, P | 3 |
Campanelli, C; Campriani, S; Cozzolino, G | 1 |
Chazot, G; Confavreux, C; Maugiere, F; Schott, B | 1 |
Beal, MF; Bird, ED; Matson, WR; Milbury, P; Ogawa, T; Ryan, EA; Storey, E | 1 |
Marek, KL; McCance-Katz, EF; Price, LH | 1 |
Beal, MF; Bird, ED; Matson, WR; Milbury, P; Myers, RH; Ogawa, T; Saso, S | 1 |
Plewig, G; Reinauer, S | 1 |
Meltzer, HY; Parsa, MA; Ramirez, LF; Rohr, T | 1 |
van Praag, HM | 1 |
Fisher, H; Sandyk, R | 1 |
Dichgans, J; Scholz, E | 1 |
Leathwood, PD | 2 |
Schnaberth, G | 1 |
Birkmayer, W | 1 |
Harvey, NS | 1 |
Demling, J | 1 |
Slevin, JT; Sparks, DL | 1 |
Bermejo Pareja, F; de Yébenes, JG; Martinez-Martin, P; Muradas, V | 1 |
Hall, CD; Mozzis, CE; Prange, AJ; Weiss, EA | 1 |
Alunno, S; Campriani, S; Cozzolino, G; Giannini, R; Giombini, L | 1 |
Nistri, A | 1 |
Birkmayer, W; Neumayer, E | 2 |
Carroll, JD; Coppen, A; Metcalfe, M; Morris, JG | 1 |
Chase, TN; Murphy, DL; Pérez-Cruet, J | 1 |
Garelis, E; Lal, S; Sourkes, TL; Young, SN | 1 |
Shibasaki, H | 1 |
Shibazaki, H | 1 |
Matussek, N | 1 |
Presthus, J | 1 |
Brossi, A; Teitel, S | 1 |
Ahmed, R; Chow, R; Dowson, JH; Gillingham, FJ; Pullar, IA | 2 |
Curzon, G; Gumpert, J; Sharpe, D | 1 |
Fodor, A; Karczag, I; Molnár, G; Szilágyi, A; Ujvárosi, I | 1 |
Barbeau, A | 1 |
Cotzias, GC; Düby, S; Ginos, J; Papavasiliou, PS; Steck, A | 1 |
Hall, CD; Morris, CE; Prange, AJ; Weiss, EA | 1 |
Arushanian, EB; Stoliarov, GV; Tolpyshev, BA | 1 |
Sakharova, AV; Stepanova, VG | 1 |
Cooksey, B; Loncin, M; O'Reilly, S | 1 |
25 review(s) available for tryptophan and Parkinson Disease
Article | Year |
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Can kynurenine pathway be considered as a next-generation therapeutic target for Parkinson's disease? An update information.
Topics: 3-Hydroxyanthranilic Acid; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Levodopa; Parkinson Disease; Quinolinic Acid; Tryptophan | 2022 |
Dynamic changes in metabolites of the kynurenine pathway in Alzheimer's disease, Parkinson's disease, and Huntington's disease: A systematic Review and meta-analysis.
Topics: 3-Hydroxyanthranilic Acid; Adenosine; Alzheimer Disease; Humans; Huntington Disease; Hydroxyindoleacetic Acid; Kynurenic Acid; Kynurenine; NAD; Niacinamide; Parkinson Disease; Tryptophan | 2022 |
Exploring the Etiological Links behind Neurodegenerative Diseases: Inflammatory Cytokines and Bioactive Kynurenines.
Topics: Alzheimer Disease; Anti-Inflammatory Agents; Biomarkers; Cytokines; Humans; Huntington Disease; Inflammation; Kynurenine; Neurodegenerative Diseases; Parkinson Disease; Reactive Oxygen Species; Tryptophan | 2020 |
TRYCAT pathways link peripheral inflammation, nicotine, somatization and depression in the etiology and course of Parkinson's disease.
Topics: Animals; Depression; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inflammation; Nicotine; Parkinson Disease; Signal Transduction; Somatoform Disorders; Tryptophan | 2014 |
Neurodegeneration in Parkinson's disease: interactions of oxidative stress, tryptophan catabolites and depression with mitochondria and sirtuins.
Topics: Animals; Brain; Depression; Humans; Lipid Peroxidation; Mitochondria; Nerve Degeneration; Oxidative Stress; Parkinson Disease; Sirtuins; Tryptophan | 2014 |
Indoleamine 2,3 Dioxygenase as a Potential Therapeutic Target in Huntington's Disease.
Topics: Alzheimer Disease; Animals; Humans; Huntington Disease; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Parkinson Disease; Signal Transduction; Tryptophan | 2015 |
Gut Permeability and Microbiota in Parkinson's Disease: Role of Depression, Tryptophan Catabolites, Oxidative and Nitrosative Stress and Melatonergic Pathways.
Topics: Depression; Gastrointestinal Microbiome; Humans; Inflammation; Intestinal Mucosa; Intestines; Melatonin; Nitrosative Stress; Oxidation-Reduction; Parkinson Disease; Permeability; Tryptophan | 2016 |
The Microbiome-Gut-Brain Axis in Health and Disease.
Topics: Animals; Autistic Disorder; Brain; Cytokines; Depression; Fatty Acids, Volatile; gamma-Aminobutyric Acid; Gastrointestinal Microbiome; Gastrointestinal Tract; Humans; Irritable Bowel Syndrome; Parkinson Disease; Prebiotics; Probiotics; Tryptophan; Vagus Nerve | 2017 |
Altered tryptophan metabolism in Parkinson's disease: a possible novel therapeutic approach.
Topics: Antiparkinson Agents; Humans; Kynurenine; Levodopa; Parkinson Disease; Tryptophan | 2011 |
The kynurenine pathway in neurodegenerative diseases: mechanistic and therapeutic considerations.
Topics: Aging; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Animals; Enzyme Inhibitors; Humans; Huntington Disease; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inflammation; Kynurenic Acid; Kynurenine; Microglia; Molecular Targeted Therapy; Neurodegenerative Diseases; Neurons; Neuroprotective Agents; Neurotoxins; Parkinson Disease; Quinolinic Acid; Receptors, G-Protein-Coupled; Receptors, N-Methyl-D-Aspartate; Tryptophan | 2012 |
Misincorporation of amino acid analogues into proteins by biosynthesis.
Topics: Amino Acids; Amino Acids, Diamino; Aminoacylation; Animals; Bacteria; Canavanine; Ethionine; Humans; Levodopa; Lupus Erythematosus, Systemic; Oxidation-Reduction; Parkinson Disease; Plants; Protein Biosynthesis; Tryptophan | 2008 |
Effects of foods and nutrients on brain neurotransmitters.
Topics: Amino Acids; Animals; Biological Transport, Active; Brain; Choline; Dopamine; Humans; Kinetics; Neurons; Neurotransmitter Agents; Norepinephrine; Nutritional Physiological Phenomena; Parkinson Disease; Prolactin; Serotonin; Tryptophan; Tyrosine | 1984 |
Monoamine precursors and analogues.
Topics: 5-Hydroxytryptophan; Animals; Biogenic Amines; Dihydroxyphenylalanine; Dopamine beta-Hydroxylase; Drug Interactions; Drug Synergism; Humans; Levodopa; Mice; Parkinson Disease; Rats; Receptors, Drug; Stimulation, Chemical; Tremor; Tryptophan; Tyrosine | 1975 |
Affective disorders and aggression disorders: evidence for a common biological mechanism.
Topics: 5-Hydroxytryptophan; Aggression; Blood Platelets; Carrier Proteins; Celiac Disease; Depressive Disorder; Female; Humans; Hydrocortisone; Hydroxyindoleacetic Acid; Male; Parkinson Disease; Prolactin; Receptors, Drug; Receptors, Neurotransmitter; Receptors, Serotonin; Serotonin; Suicide; Tryptophan | 1986 |
Neurotransmitter precursors: from animal experiments to human applications.
Topics: Alzheimer Disease; Animals; Behavior, Animal; Brain; Humans; Neurotransmitter Agents; Parkinson Disease; Protein Precursors; Sleep Stages; Tryptophan | 1986 |
Psychiatric disorders in parkinsonism. 1. Functional illnesses and personality.
Topics: Antidepressive Agents; Clozapine; Depressive Disorder; Dopamine; Electroconvulsive Therapy; Female; Homovanillic Acid; Humans; Levodopa; Male; Mental Disorders; Nomifensine; Nortriptyline; Parkinson Disease; Personality; Psychotic Disorders; Serotonin; Tryptophan | 1986 |
[Modern treatment of parkinsonism].
Topics: Antiparkinson Agents; Brain Stem; Dihydroxyphenylalanine; Dopamine; Drug Synergism; Female; Gastrointestinal Diseases; Humans; Hydrazines; Hydroxyindoleacetic Acid; Male; Movement Disorders; Norepinephrine; Parkinson Disease; Psychoses, Substance-Induced; Serotonin; Tryptophan | 1972 |
Monoamine metabolites in lumbar CSF: the question of their origin in relation to clinical studies.
Topics: Animals; Biological Transport, Active; Brain; Cats; Cerebral Ventricles; Cerebrospinal Fluid; Choroid Plexus; Dihydroxyphenylalanine; Dogs; Dopamine; Fenclonine; Glycols; Haplorhini; Homovanillic Acid; Humans; Hydrocephalus; Hydroxyindoleacetic Acid; Levodopa; Methoxyhydroxyphenylglycol; Parkinson Disease; Phenylacetates; Probenecid; Serotonin; Spinal Cord; Spinal Cord Injuries; Tryptophan | 1974 |
Parkinson's syndrome. Recent progress in the medical treatment and its pharmacological basis.
Topics: Amantadine; Atropine; Catecholamines; Dihydroxyphenylalanine; Histamine H1 Antagonists; Humans; Imipramine; Parkinson Disease; Tryptophan | 1971 |
[Recent advances and pharmacological basis of the medical treatment of Parkinson's syndrome].
Topics: Amantadine; Catecholamines; Dihydroxyphenylalanine; Histamine H1 Antagonists; Humans; Imipramine; Parasympatholytics; Parkinson Disease; Tryptophan | 1971 |
[Biochemistry of depression].
Topics: Animals; Bipolar Disorder; Brain; Central Nervous System; Depression; Dihydroxyphenylalanine; Glycols; Humans; Hydroxyindoleacetic Acid; Norepinephrine; Parkinson Disease; Peripheral Nerves; Phenylacetates; Serotonin; Tryptophan; Tryptophan Hydroxylase | 1972 |
[Other trials with drug therapy in parkinsonism].
Topics: 5-Hydroxytryptophan; Amitriptyline; Animals; Dihydroxyphenylalanine; Disulfiram; Drug Evaluation; Drug Therapy, Combination; Humans; Imipramine; Methyldopa; Monoamine Oxidase Inhibitors; Parkinson Disease; Picolinic Acids; Rats; Serine; Time Factors; Tryptophan; Tyrosine | 1973 |
Alkaloids in the mammalian system.
Topics: 5-Hydroxytryptophan; Acetaldehyde; Alkaloids; Animals; Aporphines; Biogenic Amines; Catalysis; Cells, Cultured; Circular Dichroism; Cyclization; Dealkylation; Dihydroxyphenylalanine; Humans; Isoquinolines; Magnetic Resonance Spectroscopy; Mammals; Methylation; Molecular Conformation; Parkinson Disease; Stereoisomerism; Tryptophan | 1974 |
Dopamine and dopamine metabolites in Parkinson's disease-a review.
Topics: Brain Chemistry; Dopamine; Humans; Movement Disorders; Parkinson Disease; Phenylacetates; Tryptophan; Tyrosine | 1968 |
Metabolic modification of Parkinson's disease and of chronic manganese poisoning.
Topics: Animals; Brain; Choline; Chronic Disease; Dihydroxyphenylalanine; Drug Synergism; Humans; Manganese Poisoning; Melatonin; Methionine; Monoamine Oxidase Inhibitors; Parkinson Disease; Phenylalanine; Poisoning; Pyridoxine; Tryptophan; Tyrosine | 1971 |
9 trial(s) available for tryptophan and Parkinson Disease
Article | Year |
---|---|
Effects of acute tryptophan depletion on neuropsychological and motor function in Parkinson's disease.
Topics: Aged; Aged, 80 and over; Cognition; Cross-Over Studies; Deficiency Diseases; Double-Blind Method; Female; Humans; Male; Memory, Short-Term; Middle Aged; Movement Disorders; Neuropsychological Tests; Parkinson Disease; Psychomotor Performance; Reaction Time; Serotonin; Severity of Illness Index; Tryptophan | 2010 |
The effects of acute tryptophan depletion on mood in patients with Parkinson's disease and the healthy elderly.
Topics: Affect; Age Factors; Aged; Antiparkinson Agents; Cross-Over Studies; Depression; Double-Blind Method; Humans; Middle Aged; Parkinson Disease; Placebo Effect; Psychiatric Status Rating Scales; Serotonin; Severity of Illness Index; Tryptophan | 2010 |
Dynamic, adaptive changes in MAO-A binding after alterations in substrate availability: an in vivo [(11)C]-harmine positron emission tomography study.
Topics: Carbidopa; Carbon Radioisotopes; Corpus Striatum; Dopamine; Dopamine Agonists; Drug Combinations; Harmine; Humans; Levodopa; Monoamine Oxidase; Parkinson Disease; Positron-Emission Tomography; Prefrontal Cortex; Protein Binding; Serotonin; Substrate Specificity; Time Factors; Tryptophan | 2012 |
Hypothalamic digoxin-mediated model for Parkinson's disease.
Topics: Aged; Digoxin; Dolichols; Enzyme Inhibitors; Erythrocytes; Female; Glycoconjugates; Glycosaminoglycans; Humans; Hydroxymethylglutaryl CoA Reductases; Hypothalamus; Male; Membrane Proteins; Middle Aged; Models, Biological; Neurons; Parkinson Disease; Polyisoprenyl Phosphates; Sodium-Potassium-Exchanging ATPase; Tryptophan; Tyrosine; Ubiquinone | 2003 |
The serotonergic hypothesis for depression in Parkinson's disease: an experimental approach.
Topics: Affect; Aged; Brain; Causality; Cross-Over Studies; Depressive Disorder; Double-Blind Method; Female; Food, Formulated; Humans; Male; Middle Aged; Neuropsychological Tests; Parkinson Disease; Serotonin; Surveys and Questionnaires; Synaptic Transmission; Tryptophan | 2006 |
Effects of acute tryptophan depletion on cognition, memory and motor performance in Parkinson's disease.
Topics: Aged; Amino Acids; Cognition; Cross-Over Studies; Double-Blind Method; Female; Humans; Male; Memory; Middle Aged; Neuropsychological Tests; Parkinson Disease; Psychomotor Performance; Reaction Time; Severity of Illness Index; Tryptophan | 2006 |
L-tryptophan in the treatment of levodopa induced psychiatric disorders.
Topics: Aged; Aged, 80 and over; Antiparkinson Agents; Brain; Female; Humans; Levodopa; Male; Mental Disorders; Middle Aged; Parkinson Disease; Serotonin; Single-Blind Method; Treatment Outcome; Tryptophan | 1974 |
Mental symptoms in Parkinson's disease during chronic treatment with levodopa.
Topics: Adult; Aged; Delirium; Dementia; Female; Humans; Levodopa; Male; Mental Disorders; Middle Aged; Parkinson Disease; Parkinson Disease, Postencephalitic; Tryptophan | 1976 |
Levodopa and L-tryptophan therapy in Parkinsonism.
Topics: Aged; Depression; Dihydroxyphenylalanine; Female; Gait; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Nausea; Occupational Therapy; Parkinson Disease; Personality Inventory; Physical Therapy Modalities; Posture; Psychiatric Status Rating Scales; Spasm; Speech Therapy; Tremor; Tryptophan | 1972 |
71 other study(ies) available for tryptophan and Parkinson Disease
Article | Year |
---|---|
Tryptophan 2,3-dioxygenase, a novel therapeutic target for Parkinson's disease.
Topics: Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Parkinson Disease; Tryptophan; Tryptophan Oxygenase | 2021 |
Imaging of cerebral tryptophan metabolism using 7-[
Topics: Animals; Disease Models, Animal; Fluorine Radioisotopes; Hippocampus; Kynurenine; Male; Melatonin; Oxidopamine; Parkinson Disease; Pineal Gland; Positron-Emission Tomography; Radiopharmaceuticals; Rats; Rats, Long-Evans; Serotonin; Tryptophan | 2022 |
Exposure to the environmentally toxic pesticide maneb induces Parkinson's disease-like neurotoxicity in mice: A combined proteomic and metabolomic analysis.
Topics: alpha-Synuclein; Animals; Environmental Pollutants; Fungicides, Industrial; Humans; Maneb; Metabolomics; Mice; Neuroblastoma; Neurotoxicity Syndromes; Paraquat; Parkinson Disease; Pesticides; Phenylalanine; Proteomics; Tryptophan | 2022 |
Single Nucleotide Polymorphisms of Indoleamine 2,3-Dioxygenase 1 Influenced the Age Onset of Parkinson's Disease.
Topics: Biomarkers; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Parkinson Disease; Polymorphism, Single Nucleotide; Tryptophan | 2022 |
Faecal metabolite deficit, gut inflammation and diet in Parkinson's disease: Integrative analysis indicates inflammatory response syndrome.
Topics: Benzoates; Diet; Humans; Inflammation; Leukocyte L1 Antigen Complex; Maltose; Parkinson Disease; Tryptophan | 2023 |
Tryptophan Metabolites Are Associated With Symptoms and Nigral Pathology in Parkinson's Disease.
Topics: Biomarkers; Humans; Kynurenine; Parkinson Disease; Substantia Nigra; Tryptophan | 2020 |
Tryptophan in the diet ameliorates motor deficits in a rotenone-induced rat Parkinson's disease model via activating the aromatic hydrocarbon receptor pathway.
Topics: Animals; Diet; Disease Models, Animal; Hydrocarbons, Aromatic; Neuroprotective Agents; Parkinson Disease; Rats; Rotenone; Tryptophan | 2021 |
A novel Parkinson's disease risk variant, p. W378R, in the Gaucher's disease GBA gene.
Topics: Adult; Aged; Arginine; Family Health; Female; Gaucher Disease; Glucosylceramidase; Humans; Male; Middle Aged; Mutation; Parkinson Disease; Tryptophan | 2018 |
Membrane bound α-synuclein is fully embedded in the lipid bilayer while segments with higher flexibility remain.
Topics: Acrylamide; alpha-Synuclein; Amino Acid Sequence; Cell Membrane; Humans; Lipid Bilayers; Lipids; Micelles; Molecular Sequence Data; Parkinson Disease; Phosphatidylcholines; Phosphatidylserines; Protein Binding; Protein Structure, Tertiary; Tryptophan | 2013 |
Effects of L-tryptophan on L-DOPA-induced dyskinesia in the L-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-treated macaque model of Parkinson's disease.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Antiparkinson Agents; Corpus Striatum; Dopamine; Dyskinesia, Drug-Induced; Female; Levodopa; Macaca fascicularis; Motor Activity; Parkinson Disease; Tryptophan | 2014 |
NMDA antagonists as Parkinson's disease therapy: disseminating the evidence.
Topics: Animals; Antiparkinson Agents; Excitatory Amino Acid Antagonists; Glutamic Acid; Humans; Parkinson Disease; Receptors, N-Methyl-D-Aspartate; Tryptophan | 2014 |
LC-MS-based urinary metabolite signatures in idiopathic Parkinson's disease.
Topics: alpha-Synuclein; Animals; Biomarkers; Chromatography, Liquid; Drosophila melanogaster; Fatty Acids; Histidine; Humans; Kynurenine; Mass Spectrometry; Metabolomics; Nucleotides; Parkinson Disease; Phenotype; Phenylalanine; Steroids; Tryptophan; Tyrosine | 2015 |
Structural features of membrane-bound glucocerebrosidase and α-synuclein probed by neutron reflectometry and fluorescence spectroscopy.
Topics: alpha-Synuclein; Gaucher Disease; Glucosylceramidase; Humans; Lipid Bilayers; Mutation; Neutron Diffraction; Parkinson Disease; Protein Binding; Spectrometry, Fluorescence; Surface Plasmon Resonance; Tryptophan | 2015 |
A tripeptide isolated from Bothrops atrox venom has neuroprotective and neurotrophic effects on a cellular model of Parkinson's disease.
Topics: 1-Methyl-4-phenylpyridinium; Animals; Apoptosis; Bothrops; Caspase 3; Caspase 9; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dopamine; Dopaminergic Neurons; Glutamic Acid; Mitochondria; Models, Biological; Neuroprotective Agents; Parkinson Disease; PC12 Cells; Peptides; Rats; Tryptophan; Valine; Venoms | 2015 |
Dynamic DNA Methylation Regulates Levodopa-Induced Dyskinesia.
Topics: Analysis of Variance; Animals; Antiparkinson Agents; Corpus Striatum; Dioxygenases; Disease Models, Animal; DNA Methylation; Dopamine; Dyskinesia, Drug-Induced; Enzyme Inhibitors; GADD45 Proteins; Gene Expression Regulation; Immunoprecipitation; Intracellular Signaling Peptides and Proteins; Levodopa; Male; Medial Forebrain Bundle; Oxidopamine; Parkinson Disease; Parkinson Disease, Secondary; Phthalimides; Rats; Rats, Sprague-Dawley; Tryptophan | 2016 |
Is Ro 61-8048 a potential fast-acting antidepressant?
Topics: Humans; Parkinson Disease; Tryptophan | 2012 |
Mutation of the PDGFRB gene as a cause of idiopathic basal ganglia calcification.
Topics: Adult; Aged; Amino Acid Substitution; Arginine; Basal Ganglia Diseases; Calcinosis; Child; Databases, Genetic; Exome; Female; Humans; Leucine; Magnetic Resonance Imaging; Male; Middle Aged; Mutation; Neurologic Examination; Parkinson Disease; Pedigree; Polymerase Chain Reaction; Proline; Receptor, Platelet-Derived Growth Factor beta; Tomography, X-Ray Computed; Tryptophan | 2013 |
Oxidative damage and cytogenic analysis in leukocytes of Parkinson's disease patients.
Topics: Cytogenetic Analysis; Homocysteine; Humans; Inflammation; Interferon-gamma; Leukocytes; Macrophages; Neopterin; Oxidative Stress; Parkinson Disease; T-Lymphocytes; Tryptophan | 2003 |
Characterization of oligomeric intermediates in alpha-synuclein fibrillation: FRET studies of Y125W/Y133F/Y136F alpha-synuclein.
Topics: alpha-Synuclein; Anilino Naphthalenesulfonates; Benzothiazoles; Fluorescence Resonance Energy Transfer; Fluorescent Dyes; Humans; Mutagenesis, Site-Directed; Nerve Tissue Proteins; Parkinson Disease; Protein Structure, Secondary; Spectroscopy, Fourier Transform Infrared; Synucleins; Thiazoles; Tryptophan; Tyrosine | 2005 |
Monoamine metabolites in human cerebrospinal fluid. HPLC/ED method.
Topics: 3,4-Dihydroxyphenylacetic Acid; Alzheimer Disease; Chromatography, High Pressure Liquid; Depression; Dihydroxyphenylalanine; Electrochemistry; Glycols; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Methoxyhydroxyphenylglycol; Parkinson Disease; Phenylacetates; Subarachnoid Hemorrhage; Tryptophan; Tyrosine | 1984 |
Pyridoxal phosphate, tryptophan, and tyrosine in blood and cerebrospinal fluid in elderly patients.
Topics: Adult; Age Factors; Aged; Humans; Hydrocephalus; Middle Aged; Parkinson Disease; Pyridoxal Phosphate; Tryptophan; Tyrosine | 1984 |
The effect of carbidopa and benserazide on human plasma 5-hydroxytryptophan levels.
Topics: 5-Hydroxytryptophan; Adult; Benserazide; Carbidopa; Chlorpromazine; Dihydroxyphenylalanine; Humans; Hydrazines; Middle Aged; Parkinson Disease; Schizophrenia; Tryptophan | 1982 |
Tryptophan deficiency stupor--a new psychiatric syndrome.
Topics: Aged; Animals; Carcinoid Tumor; Female; Humans; Levodopa; Malabsorption Syndromes; Male; Mental Disorders; Middle Aged; Muscles; Parkinson Disease; Serotonin; Syndrome; Tryptophan | 1982 |
L-dopa competes with tyrosine and tryptophan for human brain uptake.
Topics: Aged; Benserazide; Blood-Brain Barrier; Brain; Female; Humans; Levodopa; Male; Parkinson Disease; Tryptophan; Tyrosine | 1980 |
Treatment with tryptophan of levodopa-associated psychiatric disturbances.
Topics: Aged; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Psychiatric Status Rating Scales; Psychoses, Substance-Induced; Tryptophan | 1980 |
Duration of illness and response to tryptophan in Parkinson's disease.
Topics: Dreams; Female; Humans; Male; Parkinson Disease; Psychiatric Status Rating Scales; Tryptophan | 1980 |
Concentrations of serotonin and its related substances in the cerebrospinal fluid of parkinsonian patients and their relations to the severity of symptoms.
Topics: 5-Hydroxytryptophan; Humans; Hydroxyindoleacetic Acid; Kynurenine; Middle Aged; Parkinson Disease; Reference Values; Serotonin; Tryptophan | 1993 |
Serotonin and Parkinson's disease.
Topics: Basal Ganglia Diseases; Depressive Disorder; Dopamine; Drug Therapy, Combination; Fluoxetine; Humans; Levodopa; Parkinson Disease; Serotonin; Tryptophan | 1993 |
Endogenous alkaloids in the brain of rats loaded with tyrosine/tryptophan & in the serum of patients of neurodegenerative & psychiatric disorders.
Topics: Alkaloids; Animals; Bipolar Disorder; Brain; Chromatography, High Pressure Liquid; Epilepsy; Female; Humans; Parkinson Disease; Rats; Rats, Sprague-Dawley; Tryptophan; Tyrosine | 1998 |
Tryptophan and tyrosine catabolic pattern in neuropsychiatric disorders.
Topics: Adult; Biogenic Monoamines; Brain Diseases; Brain Neoplasms; Digoxin; Epilepsy, Generalized; Erythrocytes; Fatty Acids, Nonesterified; Female; Glioma; Glycine Agents; Humans; Hydroxymethylglutaryl CoA Reductases; Kynurenic Acid; Magnesium; Male; Microvascular Angina; Middle Aged; Morphine; Narcotics; Nicotine; Nicotinic Agonists; Parkinson Disease; Quinolinic Acid; Schizophrenia; Serum Albumin; Sodium-Potassium-Exchanging ATPase; Strychnine; Tryptophan; Tyrosine; Ubiquinone | 2000 |
Increased neopterin production and tryptophan degradation in advanced Parkinson's disease.
Topics: Aged; Chromatography, High Pressure Liquid; Female; Humans; Immunity, Cellular; Kynurenine; Male; Neopterin; Parkinson Disease; Tryptophan | 2002 |
Letter: Do changes in blood levels of other aromatic aminoacids influence levodopa therapy?
Topics: Amino Acids; Blood-Brain Barrier; Histidine; Humans; Levodopa; Parkinson Disease; Phenylalanine; Tryptophan | 1976 |
[Psychopharmacology of tryptophan (author's transl)].
Topics: Animals; Bipolar Disorder; Depression; Humans; Mental Disorders; Parkinson Disease; Schizophrenia; Serotonin; Sleep; Tryptophan | 1977 |
Niacin depletion in Parkinsonian patients treated with L-dopa, benserazide and carbidopa.
Topics: Adolescent; Adult; Benserazide; Bromocriptine; Carbidopa; Female; Humans; Hydrazines; Levodopa; Male; Micrococcus; Middle Aged; Nicotinamidase; Nicotinic Acids; Parkinson Disease; Tryptophan | 1979 |
Untreated acrodermatitis enteropathica in adults.
Topics: Acrodermatitis; Adult; Age Factors; Female; Humans; Malabsorption Syndromes; Male; Parkinson Disease; Paronychia; Syndrome; Tryptophan; Zinc | 1978 |
L-tryptophan administration in L-dopa-induced hallucinations in elderly Parkinsonian patients.
Topics: Aged; Female; Hallucinations; Humans; Levodopa; Male; Middle Aged; Parkinson Disease; Tryptophan | 1977 |
Dopaminergic supersensitivity in parkinsonism.
Topics: Aged; Benzyl Compounds; Brain; Brain Chemistry; Dopamine; Drug Therapy, Combination; Female; Humans; Hydrazines; Hydroxyindoleacetic Acid; Levodopa; Nerve Degeneration; Norepinephrine; Parkinson Disease; Psychoses, Substance-Induced; Serotonin; Tryptophan; Tyrosine | 1975 |
Tryptophan/nicotinic acid pathway during levodopa treatment of Parkinsonism.
Topics: Adult; Aged; Female; Humans; Levodopa; Male; Middle Aged; Nicotinic Acids; Parkinson Disease; Tryptophan | 1975 |
[Letter: Effectiveness of L-tryptophan on Parkinsonian tremor. Preliminary study].
Topics: Adult; Aged; Drug Evaluation; Female; Humans; Male; Middle Aged; Parkinson Disease; Tryptophan | 1976 |
Kynurenic acid concentrations are reduced in Huntington's disease cerebral cortex.
Topics: Aged; Alzheimer Disease; Cerebral Cortex; Energy Metabolism; Free Radicals; Humans; Huntington Disease; Kynurenic Acid; Kynurenine; Middle Aged; Parkinson Disease; Purines; Tryptophan; Tyrosine | 1992 |
Serotonergic dysfunction in depression associated with Parkinson's disease.
Topics: Depressive Disorder; Fluvoxamine; Humans; Male; Middle Aged; Neurotransmitter Uptake Inhibitors; Parkinson Disease; Serotonin; Tryptophan | 1992 |
Kynurenine pathway abnormalities in Parkinson's disease.
Topics: Aged; Autopsy; Brain; Female; Humans; Kynurenine; Male; Parkinson Disease; Tryptophan; Tyrosine | 1992 |
[Eosinophilia-myalgia syndrome].
Topics: Aged; Biopsy; Electromyography; Eosinophilia; Female; Humans; Middle Aged; Muscles; Neuromuscular Diseases; Parkinson Disease; Scleroderma, Systemic; Skin; Sleep Initiation and Maintenance Disorders; Syndrome; Tryptophan | 1991 |
Neuroleptic malignant syndrome without neuroleptics.
Topics: Aged; Aged, 80 and over; Antiparkinson Agents; Carbidopa; Depressive Disorder; Drug Combinations; Drug Therapy, Combination; Female; Humans; Levodopa; Neuroleptic Malignant Syndrome; Parkinson Disease; Substance Withdrawal Syndrome; Tranylcypromine; Tryptophan | 1990 |
L-tryptophan supplementation in Parkinson's disease.
Topics: Aged; Drug Therapy, Combination; Female; Humans; Levodopa; Middle Aged; Parkinson Disease; Tryptophan | 1989 |
Treatment of drug-induced exogenous psychosis in parkinsonism with clozapine and fluperlapine.
Topics: Aged; Antipsychotic Agents; Benserazide; Bromocriptine; Clozapine; Delusions; Dibenzazepines; Dose-Response Relationship, Drug; Drug Therapy, Combination; Hallucinations; Humans; Hydrazines; Levodopa; Male; Middle Aged; Parkinson Disease; Psychoses, Substance-Induced; Tryptophan | 1985 |
Neurotransmitter precursors and brain function.
Topics: Aged; Aging; Alzheimer Disease; Animals; Biological Transport; Brain; Diet; Humans; Learning; Levodopa; Memory; Neurotransmitter Agents; Parkinson Disease; Phosphatidylcholines; Serotonin; Sleep; Tryptophan | 1986 |
[Depression and Parkinson syndrome].
Topics: Antidepressive Agents; Brain; Depressive Disorder; Drug Therapy, Combination; Humans; Levodopa; Neurotransmitter Agents; Parkinson Disease; Tryptophan | 1986 |
Milestones in the development of modern Parkinson therapy.
Topics: 2,3-Diketogulonic Acid; Alloxan; Behavior; Bromocriptine; Drug Combinations; Drug Therapy, Combination; Ferric Compounds; Humans; Levodopa; Neurology; Parkinson Disease; Selegiline; Tryptophan | 1987 |
[L-dopa-induced psychoses and their treatment with L-tryptophan].
Topics: Humans; Levodopa; Parkinson Disease; Psychoses, Substance-Induced; Tryptophan | 1986 |
Determination of tyrosine, tryptophan and their metabolic derivatives by liquid chromatography-electrochemical detection: application to post mortem samples from patients with Parkinson's and Alzheimer's disease.
Topics: Aged; Alzheimer Disease; Animals; Chromatography, High Pressure Liquid; Electrochemistry; Female; Humans; Male; Middle Aged; Parkinson Disease; Rats; Tryptophan; Tyrosine | 1985 |
Carbidopa dosage modifies L-dopa induced side effects and blood levels of L-dopa and other amino acids in advanced parkinsonism.
Topics: Aged; Carbidopa; Drug Therapy, Combination; Female; Homovanillic Acid; Humans; Kinetics; Levodopa; Male; Middle Aged; Parkinson Disease; Tryptophan; Tyrosine | 1985 |
Levodopa and depression in parkinsonism.
Topics: Depression; Dihydroxyphenylalanine; Drug Synergism; Humans; Parkinson Disease; Tryptophan | 1971 |
Inefficacy of tryptophan-pyridoxine in essential tremor.
Topics: Basal Ganglia; Dihydroxyphenylalanine; Drug Synergism; Female; Humans; Male; Parkinson Disease; Pyridoxine; Tremor; Tryptophan | 1971 |
Tryptophan nicotinic-acid metabolism during levodopa treatment of parkinsonism.
Topics: Dihydroxyphenylalanine; Humans; Male; Middle Aged; Nicotinic Acids; Parkinson Disease; Tryptophan | 1971 |
Levodopa and L-tryptophan in parkinsonism.
Topics: Brain; Dihydroxyphenylalanine; Drug Synergism; Humans; Parkinson Disease; Tryptophan | 1972 |
Dietary regulation of brain tryptophan metabolism by plasma ratio of free tryptophan and neutral amino acids in humans.
Topics: Amino Acids; Blood Proteins; Brain; Diet; Eating; Fasting; Feeding Behavior; Humans; Huntington Disease; Hydroxyindoleacetic Acid; Parkinson Disease; Protein Binding; Tryptophan | 1974 |
[Malignant melanoma and L-dopa. Review of literature on the problem of causal relationship].
Topics: Humans; Levodopa; Male; Melanins; Melanoma; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Parkinson Disease; Skin Neoplasms; Tryptophan | 1974 |
[L-tryptophan therapy of DOPA psychoses].
Topics: Aged; Athetosis; Cardiovascular Diseases; Chorea; Constipation; Dihydroxyphenylalanine; Feeding and Eating Disorders; Female; Humans; Male; Middle Aged; Parkinson Disease; Psychoses, Substance-Induced; Seizures; Sleep Wake Disorders; Tryptophan; Vertigo; Vomiting | 1972 |
The balance of biogenic amines as condition for normal behaviour.
Topics: Aged; Benzyl Compounds; Brain; Dihydroxyphenylalanine; Dopamine; Electroencephalography; Female; Humans; Hydrazines; Hydroxyindoleacetic Acid; Male; Middle Aged; Norepinephrine; Parkinson Disease; Phenylacetates; Psychoses, Substance-Induced; Serine; Serotonin; Tryptophan | 1972 |
Biochemical investigations in Parkinsonism. A study of the metabolites of the biogenic amines in the lumbar CSF.
Topics: Dihydroxyphenylalanine; Dopamine; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Microscopy, Fluorescence; Parkinson Disease; Phenylacetates; Tryptophan | 1972 |
Amine metabolites in the cerebrospinal fluid in Parkinson's disease and the response to levodopa.
Topics: Adult; Aged; Dihydroxyphenylalanine; Dopamine; Dose-Response Relationship, Drug; Electroencephalography; Evaluation Studies as Topic; Female; Follow-Up Studies; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Parkinson Disease; Phenylacetates; Serotonin; Tryptophan | 1973 |
Tryptophan malabsorption in levodopa-treated parkinsonian patients. Effect of tryptophan on mental disturbances.
Topics: Aged; Brain; Dementia; Depression, Chemical; Dihydroxyphenylalanine; Female; Humans; Hydroxyindoleacetic Acid; Intestinal Absorption; Male; Mental Disorders; Middle Aged; Parkinson Disease; Serotonin; Tryptophan | 1973 |
5-Hydroxyindoleacetic acid in cerebrospinal fluid.
Topics: Adult; Age Factors; Brain Diseases; Brain Stem; Depression; Epilepsy; Humans; Hydroxyindoleacetic Acid; Mental Disorders; Middle Aged; Neurocognitive Disorders; Paralysis; Parkinson Disease; Probenecid; Spectrometry, Fluorescence; Spinal Cord Compression; Tabes Dorsalis; Tryptophan | 1973 |
[Serum tryptophan in cases with senile dementia, parkinsonism and normal cases].
Topics: Adult; Aged; Dementia; Dihydroxyphenylalanine; Female; Humans; Male; Middle Aged; Parkinson Disease; Time Factors; Tryptophan | 1974 |
Nucleus ruber and L-dopa psychosis: biochemical post-mortem findings.
Topics: Aged; Amygdala; Autopsy; Biogenic Amines; Caudate Nucleus; Corpus Striatum; Dihydroxyphenylalanine; Dopamine; Female; Globus Pallidus; Gyrus Cinguli; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Norepinephrine; Parkinson Disease; Psychoses, Substance-Induced; Red Nucleus; Serotonin; Substantia Nigra; Tryptophan; Tyrosine | 1974 |
Rapid deterioration in patients with parkinsonism following tryptophan-pyridoxine administration.
Topics: Adult; Brain; Drug Synergism; Humans; Male; Middle Aged; Parkinson Disease; Pyridoxine; Reaction Time; Tryptophan | 1972 |
Biochemical investigations in Parkinsonism. A study of the metabolites of the biogenic amines in the lumbar CSF.
Topics: Caudate Nucleus; Dihydroxyphenylalanine; Humans; Hydroxyindoleacetic Acid; Microscopy, Fluorescence; Parkinson Disease; Phenylacetates; Serotonin; Tryptophan | 1972 |
[The effect of phenamine on medicinal parkinsonism and retardation of movement upon stimulation of the caudate nucleus (a clinico-experimental study)].
Topics: Amphetamine; Caudate Nucleus; Female; Haloperidol; Humans; Male; Parkinson Disease; Parkinson Disease, Secondary; Schizophrenia; Tryptophan | 1970 |
[The protein nature of specific cellular inclusions (Lewy's bodies) in Parkinson's disease].
Topics: Acetylcholinesterase; Acid Phosphatase; Alkaline Phosphatase; Amino Acids; Cholinesterases; Cystine; Cytoplasmic Granules; Histidine; Histocytochemistry; Humans; Lipase; Lysine; Microscopy, Electron; Neurons; Parkinson Disease; Proteins; Substantia Nigra; Sulfites; Tryptophan; Tyrosine | 1967 |
Dopamine and basal ganglia disorders.
Topics: Adult; Basal Ganglia; Dopamine; Female; Hepatolenticular Degeneration; Humans; Hydroxyindoleacetic Acid; In Vitro Techniques; Infant, Newborn; Male; Malignant Carcinoid Syndrome; Middle Aged; Movement Disorders; Parkinson Disease; Phenylalanine; Pregnancy; Serotonin; Tryptophan; Urine | 1965 |