tryptophan and Pancreatic Neoplasms

tryptophan has been researched along with Pancreatic Neoplasms in 30 studies

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19907 (23.33)18.7374
1990's1 (3.33)18.2507
2000's2 (6.67)29.6817
2010's8 (26.67)24.3611
2020's12 (40.00)2.80

Authors

AuthorsStudies
Brooks, DG; Chaharlangi, D; Ciudad, MT; Co, IL; Foerster, EG; Gallinger, S; Grünwald, BT; Guo, M; Halaby, MJ; Hezaveh, K; Jang, GH; Jin, R; Khokha, R; Klötgen, A; Lamorte, S; Liu, ZQ; Makhijani, P; Maughan, H; McGaha, TL; McGuigan, AP; Navarre, WW; Neufeld, L; O'Kane, GM; Ohashi, PS; Philpott, DJ; Pinto, DM; Pugh, TJ; Quevedo, R; Shinde, RS; Zhang, X1
Bhutia, YD; Ibrahim, AF; Korac, K; Rajasekaran, D; Schniers, BK; Sniegowski, T1
Graor, HJ; Hajihassani, O; Hue, JJ; Ji, K; Katayama, ES; Loftus, AW; Vaziri-Gohar, A; Winter, JM; Zarei, M1
Amend, L; Bielecka, AA; Boeck, S; Bokemeyer, C; Bröring, TS; Cortesi, F; Gagliani, N; Giannou, AD; Güngör, C; Huber, S; Izbicki, JR; Jung, M; Kimmelman, AC; Konczalla, L; Kylies, D; Lesker, TR; Pelczar, P; Peschka, M; Puelles, VG; Renné, T; Riecken, K; Schönlein, M; Sinn, M; Siveke, JT; Stein, A; Strowig, T; Tintelnot, J; Trajkovic-Arsic, M; Uzunoglu, FG; Xu, Y; Zhang, D1
Barranco, C1
Li, QQ; Liu, YM; Yang, B; Yang, T1
Agulló-Ortuño, MT; Flández, M; Grau, M; López-Martín, JA; Mancebo, E; Núñez Sobrino, JA; Paz-Ares, L1
Cao, Z; Hu, X; Luo, X; Wei, W; Wu, B; Zhang, N; Zhang, W1
Chen, X; Fu, Y; Gong, T; Han, X; Hu, Y; John Kao, W; Wang, M; Xu, Y; Zhang, ZR1
Bhutia, YD; Cai, A; Chen, R; Chen, Z; Ganapathy, V; Kou, L; Li, C; Lin, X; Yao, Q; Zheng, H1
Clauss, D; Pal, A; Schmidt, ME; Steindorf, K; Ulrich, CM; Wiskemann, J; Zimmer, P1
Athineos, D; Blyth, K; Falcone, M; Huerta Uribe, A; Maddocks, ODK; Newman, AC; Pietzke, M; Vazquez, A; Zhang, T1
Wu, KK1
Chang, CH; Jiang, J; Jiang, W; Liao, YP; Liu, X; Lu, J; Meng, H; Nel, AE; Salazar, F; Sun, B; Wang, X; Wu, AM1
Alahdal, M; Liang, J; Tang, T; Xing, Y1
Botwinick, IC; Chabot, JA; Cooper, T; Mann, JJ; Pursell, L; Yu, G1
Fukutake, N; Hiraoka, N; Imaizumi, A; Ito, T; Katayama, K; Kikuchi, S; Ono, N; Saruki, N; Shimada, K; Shiraishi, K; Ueno, M; Yamakado, M; Yamamoto, H1
Bonior, J; Goralska, M; Jastrzebska, M; Jaworek, J; Leja-Szpak, A; Link-Lenczowski, P; Nawrot-Porabka, K; Pierzchalski, P1
Bhutia, YD; Cao, S; Coothankandaswamy, V; Ganapathy, V; Ogura, J; Prasad, PD; Reynolds, CP; Singh, PK; Xu, Y; Yang, S1
Li, Y; Wang, C; Xu, J; Zou, H1
Bader, M; Peter, JU; Walther, DJ1
Hirayama, C; Yoshida, K1
Harper, PV; Kirchner, PT; Ryan, J; Zalutsky, M1
Hill, MJ1
Falconer, JS; Fearon, KC; McMillan, DC; Preston, T; Shenkin, A; Slater, C1
Chidambaram, A; Fraser, MC; Goldstein, AM; Struewing, JP; Tucker, MA1
Andrews, GA; Buonocore, E; Collmann, IR; Gibbs, WD; Hayes, RL; Hübner, KF; Washburn, LC1
Butler, TA; Byrd, BL; Hayes, RL; Sun, TT; Washburn, LC1
Buffa, R; Grimelius, L; Håkanson, R; Larsson, LI; Solcia, E; Sundler, F1
Debry, G; Laurent, J1

Reviews

2 review(s) available for tryptophan and Pancreatic Neoplasms

ArticleYear
Cytoguardin: A Tryptophan Metabolite against Cancer Growth and Metastasis.
    International journal of molecular sciences, 2021, Apr-26, Volume: 22, Issue:9

    Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line; Cell Movement; Cell Proliferation; Colorectal Neoplasms; Cyclooxygenase 2; Fibroblasts; Humans; Liver Neoplasms; Matrix Metalloproteinases; Mice; Neoplasm Metastasis; Neoplasms; Pancreatic Neoplasms; Serotonin; Tryptophan

2021
Bacterial metabolism and human carcinogenesis.
    British medical bulletin, 1980, Volume: 36, Issue:1

    Topics: Bacteria; Bile Acids and Salts; Biliary Tract Neoplasms; Cholesterol; Female; Gastrointestinal Neoplasms; Humans; Neoplasms; Nitrosamines; Nitroso Compounds; Pancreatic Neoplasms; Phenols; Schistosomiasis; Tryptophan; Tyrosine; Urinary Bladder Neoplasms; Uterine Cervical Neoplasms

1980

Trials

1 trial(s) available for tryptophan and Pancreatic Neoplasms

ArticleYear
Resistance Exercise Modulates Kynurenine Pathway in Pancreatic Cancer Patients.
    International journal of sports medicine, 2021, Volume: 42, Issue:1

    Topics: Biomarkers; Disease Progression; Down-Regulation; Humans; Interleukin-6; Kynurenine; Metabolic Networks and Pathways; Middle Aged; Pancreatic Neoplasms; Resistance Training; Tryptophan

2021

Other Studies

27 other study(ies) available for tryptophan and Pancreatic Neoplasms

ArticleYear
Tryptophan-derived microbial metabolites activate the aryl hydrocarbon receptor in tumor-associated macrophages to suppress anti-tumor immunity.
    Immunity, 2022, 02-08, Volume: 55, Issue:2

    Topics: Animals; Carcinoma, Pancreatic Ductal; CD8-Positive T-Lymphocytes; Humans; Immune Tolerance; Indoles; Lymphocytes, Tumor-Infiltrating; Mice; Microbiota; Pancreatic Neoplasms; Prognosis; Receptors, Aryl Hydrocarbon; Tryptophan; Tumor Microenvironment; Tumor-Associated Macrophages

2022
Carbidopa, an activator of aryl hydrocarbon receptor, suppresses IDO1 expression in pancreatic cancer and decreases tumor growth.
    The Biochemical journal, 2022, 09-16, Volume: 479, Issue:17

    Topics: Animals; Carbidopa; Indoleamine-Pyrrole 2,3,-Dioxygenase; Janus Kinases; Kynurenine; Mice; Mice, Nude; Pancreatic Neoplasms; Receptors, Aryl Hydrocarbon; Signal Transduction; STAT Transcription Factors; Tryptophan

2022
IDO1 Is a Therapeutic Target for Pancreatic Cancer-Associated Depression.
    Molecular cancer therapeutics, 2022, 12-02, Volume: 21, Issue:12

    Topics: Animals; Depression; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Mice; Pancreatic Neoplasms; Tryptophan

2022
Microbiota-derived 3-IAA influences chemotherapy efficacy in pancreatic cancer.
    Nature, 2023, Volume: 615, Issue:7950

    Topics: Animals; Autophagy; Carcinoma, Pancreatic Ductal; Disease Models, Animal; Fecal Microbiota Transplantation; Germ-Free Life; Glutathione Peroxidase; Humans; Indoleacetic Acids; Metabolomics; Metagenome; Mice; Microbiota; Neutrophils; Pancreatic Neoplasms; Peroxidase; Reactive Oxygen Species; Tryptophan

2023
Tryptophan metabolite improves PDAC response rates and survival.
    Nature reviews. Cancer, 2023, Volume: 23, Issue:5

    Topics: Carcinoma, Pancreatic Ductal; Humans; Pancreatic Neoplasms; Tryptophan

2023
T cells in pancreatic cancer stroma: Tryptophan metabolism plays an important role in immunoregulation.
    World journal of gastroenterology, 2023, May-07, Volume: 29, Issue:17

    Topics: Animals; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Mice; Pancreatic Neoplasms; Th17 Cells; Tryptophan

2023
Tryptophan Modulation in Cancer-Associated Cachexia Mouse Models.
    International journal of molecular sciences, 2023, Aug-21, Volume: 24, Issue:16

    Topics: Adenocarcinoma; Animals; Cachexia; Inflammation; Mice; Muscular Atrophy; Pancreatic Neoplasms; Quality of Life; Tryptophan

2023
Microbiota-Derived Tryptophan Metabolite Indole-3-Acetic Acid Improves Chemoresistance in Pancreatic Ductal Adenocarcinoma.
    Pancreas, 2023, May-01, Volume: 52, Issue:5

    Topics: Adenocarcinoma; Drug Resistance, Neoplasm; Humans; Microbiota; Pancreatic Neoplasms; Tryptophan

2023
Hierarchical assembly of hyaluronan coated albumin nanoparticles for pancreatic cancer chemoimmunotherapy.
    Nanoscale, 2019, Sep-21, Volume: 11, Issue:35

    Topics: Albumins; Animals; Cell Line, Tumor; Coated Materials, Biocompatible; Female; Humans; Hyaluronic Acid; Immunotherapy; Indoleamine-Pyrrole 2,3,-Dioxygenase; Mice; Nanoparticles; Neoplasm Proteins; Pancreatic Neoplasms; Pentacyclic Triterpenes; Triterpenes; Tryptophan; Tumor Microenvironment; Xenograft Model Antitumor Assays

2019
Synergism between SLC6A14 blockade and gemcitabine in pancreactic cancer: a 1H-NMR-based metabolomic study in pancreatic cancer cells.
    The Biochemical journal, 2020, 05-29, Volume: 477, Issue:10

    Topics: Amino Acid Transport Systems; Amino Acids; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tumor; Cell Movement; Cell Proliferation; Deoxycytidine; Drug Synergism; Gemcitabine; Humans; Metabolomics; Pancreatic Neoplasms; Tryptophan

2020
Immune-regulated IDO1-dependent tryptophan metabolism is source of one-carbon units for pancreatic cancer and stellate cells.
    Molecular cell, 2021, 06-03, Volume: 81, Issue:11

    Topics: Allografts; Animals; Antineoplastic Agents; Carbon; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Formates; Gene Expression Regulation, Neoplastic; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferon-gamma; Metabolic Networks and Pathways; Mice; Mice, Inbred C57BL; Mice, Nude; Oximes; Pancreatic Neoplasms; Pancreatic Stellate Cells; Proto-Oncogene Proteins p21(ras); Serine; Signal Transduction; Sulfonamides; Tryptophan; Tumor Escape; Tumor Suppressor Protein p53

2021
Nano-enabled pancreas cancer immunotherapy using immunogenic cell death and reversing immunosuppression.
    Nature communications, 2017, 11-27, Volume: 8, Issue:1

    Topics: Adaptive Immunity; Animals; Antineoplastic Agents; Apoptosis; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Drug Carriers; Feasibility Studies; Female; Forkhead Transcription Factors; Humans; Immune Tolerance; Immunity, Innate; Immunotherapy; Indoleamine-Pyrrole 2,3,-Dioxygenase; Male; Mice; Nanoparticles; Organoplatinum Compounds; Oxaliplatin; Pancreatic Neoplasms; Phospholipids; Porosity; Prodrugs; Silicon Dioxide; T-Lymphocytes, Cytotoxic; Tissue Distribution; Tryptophan; Xenograft Model Antitumor Assays

2017
1-Methyl-D-tryptophan Reduces Tumor CD133
    Scientific reports, 2018, 06-29, Volume: 8, Issue:1

    Topics: AC133 Antigen; Adenocarcinoma; Animals; Apoptosis; beta Catenin; Carcinogenesis; Caspase 3; Cell Line, Tumor; Enzyme Activation; Female; Lymphocytes; Mice; Mice, Inbred C57BL; Necrosis; Neoplastic Stem Cells; Pancreatic Neoplasms; Signal Transduction; STAT3 Transcription Factor; STAT4 Transcription Factor; Transcription Factor RelA; Tryptophan; Wnt Proteins

2018
A biological basis for depression in pancreatic cancer.
    HPB : the official journal of the International Hepato Pancreato Biliary Association, 2014, Volume: 16, Issue:8

    Topics: Adenocarcinoma; Affect; Aged; Aged, 80 and over; Depression; Female; Humans; Kynurenine; Lymphatic Metastasis; Male; Middle Aged; Pancreatic Neoplasms; Risk Factors; Signal Transduction; Surveys and Questionnaires; Tryptophan; Tumor Burden

2014
A Novel Multivariate Index for Pancreatic Cancer Detection Based On the Plasma Free Amino Acid Profile.
    PloS one, 2015, Volume: 10, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Alanine; Amino Acids; Area Under Curve; Asparagine; Body Mass Index; Cross-Sectional Studies; Early Detection of Cancer; Fasting; Female; Histidine; Humans; Isoleucine; Japan; Male; Middle Aged; Pancreatic Neoplasms; Pancreatitis, Chronic; ROC Curve; Serine; Tryptophan; Young Adult

2015
Kynuramines induce overexpression of heat shock proteins in pancreatic cancer cells via 5-hydroxytryptamine and MT1/MT2 receptors.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2015, Volume: 66, Issue:5

    Topics: Cell Line, Tumor; Heat-Shock Proteins; Humans; Ketanserin; Kynuramine; Melatonin; Pancreatic Neoplasms; Receptor, Melatonin, MT1; Receptor, Melatonin, MT2; Serotonin; Tropanes; Tryptamines; Tryptophan

2015
Amino acid transporter SLC6A14 is a novel and effective drug target for pancreatic cancer.
    British journal of pharmacology, 2016, Volume: 173, Issue:23

    Topics: Amino Acid Transport Systems; Amino Acid Transport Systems, Neutral; Animals; Antineoplastic Agents; Cell Line, Tumor; Female; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, Nude; Molecular Targeted Therapy; Pancreatic Neoplasms; RNA, Messenger; Tryptophan; Up-Regulation; Xenograft Model Antitumor Assays

2016
1-MT enhances potency of tumor cell lysate-pulsed dendritic cells against pancreatic adenocarcinoma by downregulating the percentage of Tregs.
    Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, 2010, Volume: 30, Issue:3

    Topics: Adenocarcinoma; Animals; Cancer Vaccines; Cell Line, Tumor; Dendritic Cells; Down-Regulation; Female; Male; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Pancreatic Neoplasms; T-Lymphocytes, Regulatory; Tryptophan

2010
7-Hydroxytryptophan, a novel, specific, cytotoxic agent for carcinoids and other serotonin-producing tumors.
    Cancer, 2002, Jun-15, Volume: 94, Issue:12

    Topics: 5,6-Dihydroxytryptamine; 5,7-Dihydroxytryptamine; Animals; Antineoplastic Agents; Carcinoid Tumor; Carcinoma, Small Cell; COS Cells; Humans; Lung Neoplasms; Pancreatic Neoplasms; Serotonin; Tryptophan; Tryptophan Hydroxylase; Tumor Cells, Cultured

2002
Clinical evaluation of serum levels of tryptophan in hepatobiliary disease.
    Clinica chimica acta; international journal of clinical chemistry, 1980, Feb-28, Volume: 101, Issue:2-3

    Topics: Acute Disease; Adult; Aged; Bile Duct Neoplasms; Biliary Tract Diseases; Carcinoma, Hepatocellular; Cholestasis; Chronic Disease; Fatty Acids, Nonesterified; Hepatic Encephalopathy; Hepatitis; Humans; Liver Cirrhosis; Liver Diseases; Liver Neoplasms; Middle Aged; Pancreatic Neoplasms; Serum Albumin; Tryptophan

1980
Positron emission tomography for the evaluation of pancreatic disease.
    Seminars in nuclear medicine, 1980, Volume: 10, Issue:4

    Topics: Carbon Radioisotopes; Humans; Isotope Labeling; Pancreas; Pancreatic Diseases; Pancreatic Neoplasms; Pancreatitis; Radiation Dosage; Tomography, Emission-Computed; Tryptophan

1980
Fibrinogen synthesis is elevated in fasting cancer patients with an acute phase response.
    The Journal of nutrition, 1998, Volume: 128, Issue:8

    Topics: Acute-Phase Reaction; Adenocarcinoma; Adult; Aged; Amino Acids; C-Reactive Protein; Cachexia; Fasting; Female; Fibrinogen; Glycine; Humans; Kinetics; Male; Middle Aged; Muscle Proteins; Pancreatic Neoplasms; Reference Values; Serine; Tryptophan

1998
Genotype-phenotype relationships in U.S. melanoma-prone families with CDKN2A and CDK4 mutations.
    Journal of the National Cancer Institute, 2000, Jun-21, Volume: 92, Issue:12

    Topics: Adolescent; Adult; Age Factors; Aged; Arginine; Aspartic Acid; Cyclin-Dependent Kinases; Cysteine; Genes, p16; Genotype; Germ-Line Mutation; Glycine; Haplotypes; Humans; Melanoma; Middle Aged; Nevus; Pancreatic Neoplasms; Phenotype; Skin Neoplasms; Statistics, Nonparametric; Tryptophan; United States; Valine

2000
Carbon-11-labeled amino acids for the rectilinear and positron tomographic imaging of the human pancreas.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1979, Volume: 20, Issue:6

    Topics: Carbon Radioisotopes; Humans; Injections, Intravenous; Pancreas; Pancreatic Neoplasms; Pancreatitis; Selenomethionine; Time Factors; Tomography, Emission-Computed; Tryptophan; Valine

1979
DL-[Carboxyl-11C]tryptophan, a potential agent for pancreatic imaging; production and preclinical investigations.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1979, Volume: 20, Issue:8

    Topics: Adenocarcinoma; Animals; Carbon Radioisotopes; Cholecystokinin; Cricetinae; Dogs; Female; Isotope Labeling; Male; Mesocricetus; Neoplasm Transplantation; Neoplasms, Experimental; Pancreas; Pancreatic Neoplasms; Rabbits; Radionuclide Imaging; Rats; Secretin; Stimulation, Chemical; Tissue Distribution; Transplantation, Homologous; Tryptophan

1979
Formaldehyde-ozone-induced fluorescence in gastrin-producing tumours.
    Virchows Archiv. A, Pathological anatomy and histology, 1975, Volume: 365, Issue:3

    Topics: Adult; Aged; Duodenal Neoplasms; Female; Fluorescence; Formaldehyde; Gastrins; Gastrointestinal Neoplasms; Glucagon; Humans; Insulin; Insulin Secretion; Male; Middle Aged; Ozone; Pancreatic Neoplasms; Stomach Neoplasms; Tryptophan; Zollinger-Ellison Syndrome

1975
[Biology and physiopathology of Doege-Potter syndrome].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1970, May-20, Volume: 46, Issue:24

    Topics: Blood Glucose; Endocrine System Diseases; Female; Glucose; Humans; Hypoglycemia; Insulin; Lactates; Lipid Metabolism; Lipids; Male; Mesoderm; Middle Aged; Neoplasms; Pancreatic Neoplasms; Tryptophan

1970