tryptophan and Obsessive-Compulsive Disorder

tryptophan has been researched along with Obsessive-Compulsive Disorder in 42 studies

Research

Studies (42)

TimeframeStudies, this research(%)All Research%
pre-199010 (23.81)18.7374
1990's18 (42.86)18.2507
2000's10 (23.81)29.6817
2010's4 (9.52)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Broyd, A; Hince, DA; Hood, SD; Hudaib, AR; Lee, J; Robinson, H1
Ashurov, D; Cunha, C; Mayilvahanan, K; Todorov, G1
Berk, M; Camfield, DA; Sarris, J1
Benkelfat, C; Berney, A; Blier, P; Diksic, M; Gravel, P; Leyton, M; Nakai, A; Nordahl, TE; Okazawa, H; Pinard, G; Rosa Neto, P; Sibon, I; Sookman, D; Todorov, C1
Kurup, PA; Kurup, RK2
Amiaz, R; Amital, D; Chopra, M; Sasson, Y; Zohar, J1
Callebert, J; Chabane, N; Delorme, R; Falissard, B; Launay, JM; Leboyer, M; Mouren-Siméoni, MC; Rouillon, F1
Feige, B; Kirschbaum, C; Kuelz, A; Riemann, D; Vielhaber, K; Voderholzer, U1
Benkelfat, C; Berney, A; Leyton, M; Sookman, D; Young, SN1
Berger, M; Bruestle, K; Hohagen, F; Huwig-Poppe, C; Kordon, A; Kuelz, AK; Riemann, D; Voderholzer, U1
Aldeghi, A; Arra, M; Emanuele, E; Falcone, C; Martinelli, V; Minoretti, P; Olivieri, V; Pesenti, S; Politi, P1
Kopasz, M; Külz, AK; Meinzer, S; Voderholzer, U1
Rasmussen, SA1
Anderson, GM; Chappell, PB; Goodman, WK; Leckman, JF; McDougle, CJ; McSwiggan-Hardin, M; North, WG; Pauls, DL; Price, LH; Riddle, MA1
Cowen, PJ; Fineberg, NA; Kirk, JW; Montgomery, SA1
Barr, LC; Charney, DS; Delgado, PL; Goodman, WK; Heninger, GR; McDougle, CJ; Price, LH1
Aronson, SC; Barr, LC; Goodman, WK; McDougle, CJ; Price, LH1
Bergeron, R; Blier, P1
Bellodi, L; Diaferia, G; Erzegovesi, S; Lucca, A; Moja, EA; Smeraldi, E1
Carpenter, LL; Epperson, CN; McDougle, CJ; Price, LH1
Anderson, GM; Cohen, DJ; Goodman, WK; Leckman, JF; Lynch, KA; Mazure, CM; McSwiggan-Hardin, M; Price, LH; Rasmusson, AM; Scahill, LD1
Bellodi, L; Bianchi, L; Conca, R; Erzegovesi, S; Lucca, A; Lucini, V1
McDougle, CJ1
Delgado, PL; Moreno, FA1
Baumgarten, HG; Grozdanovic, Z1
Backhaus, J; Hohagen, F; Huwig-Poppe, C; König, A; Riemann, D; Voderholzer, U1
Van der Does, AJ1
Bartlett, JR; Bellamy, C; Bridges, PK; O'Gormann, P; Patel, VK; Sepping, P; Wood, W1
Bhagavan, HN; Yaryura-Tobias, JA1
Bartlett, JR; Bridges, PK; Curzon, G; Kantamaneni, BD; Sepping, P1
Barr, LC; Goodman, WK; Price, LH1
Cowen, PJ; Power, AC1
Lucca, A; Lucini, V; Piatti, E; Ronchi, P; Smeraldi, E1
Abe, K; Terao, M; Terao, T; Yoshimura, R1
Myers, MF; Schechter, JB; Solyom, L1
Comings, BG; Comings, DE; Knell, E1
Charney, DS; Goodman, WK; Heninger, GR; Price, LH; Rasmussen, SA; Woods, SW1
Fontaine, R; Steiner, W1
Mattes, JA1
Carman, JS1
Baker, M; Bunney, WE; Goodwin, FK; Kotin, J; Miller, H; Murphy, DL1

Reviews

9 review(s) available for tryptophan and Obsessive-Compulsive Disorder

ArticleYear
Nutraceuticals in the treatment of obsessive compulsive disorder (OCD): a review of mechanistic and clinical evidence.
    Progress in neuro-psychopharmacology & biological psychiatry, 2011, Jun-01, Volume: 35, Issue:4

    Topics: 5-Hydroxytryptophan; Acetylcysteine; Dietary Supplements; Glycine; Humans; Hypericum; Inositol; Obsessive-Compulsive Disorder; Plant Preparations; Signal Transduction; Silybum marianum; Tryptophan

2011
Obsessive compulsive disorder: serotonin and beyond.
    The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry, 2000, Volume: 1, Issue:2

    Topics: Dopamine; Humans; Obsessive-Compulsive Disorder; Selective Serotonin Reuptake Inhibitors; Serotonin; Tryptophan

2000
Biological approaches to treatment-resistant obsessive compulsive disorder.
    The Journal of clinical psychiatry, 1993, Volume: 54 Suppl

    Topics: Behavior Therapy; Buspirone; Clonazepam; Combined Modality Therapy; Decision Trees; Drug Therapy, Combination; Electroconvulsive Therapy; Fenfluramine; Humans; Lithium; Obsessive-Compulsive Disorder; Phototherapy; Selective Serotonin Reuptake Inhibitors; Sleep Deprivation; Trazodone; Tryptophan

1993
A risk-benefit assessment of drugs used in the management of obsessive-compulsive disorder.
    Drug safety, 1996, Volume: 15, Issue:2

    Topics: 1-Naphthylamine; Adult; Aged; Antidepressive Agents; Buspirone; Child; Clomipramine; Clonazepam; Costs and Cost Analysis; Dopamine Antagonists; Drug Interactions; Drug Tolerance; Fenfluramine; Fluoxetine; Fluvoxamine; Humans; Lithium; Obsessive-Compulsive Disorder; Paroxetine; Risk Assessment; Selective Serotonin Reuptake Inhibitors; Sertraline; Tryptophan

1996
Update on pharmacologic management of OCD: agents and augmentation.
    The Journal of clinical psychiatry, 1997, Volume: 58 Suppl 12

    Topics: Clinical Trials as Topic; Clozapine; Dopamine Agents; Drug Therapy, Combination; Female; Fenfluramine; Haloperidol; Humans; Lithium; Middle Aged; Obsessive-Compulsive Disorder; Selective Serotonin Reuptake Inhibitors; Serotonin Agents; Treatment Outcome; Tryptophan

1997
Different roles for serotonin in anti-obsessional drug action and the pathophysiology of obsessive-compulsive disorder.
    The British journal of psychiatry. Supplement, 1998, Issue:35

    Topics: Hallucinogens; Humans; Obsessive-Compulsive Disorder; Selective Serotonin Reuptake Inhibitors; Time Factors; Tryptophan

1998
Role of serotonin in obsessive-compulsive disorder.
    The British journal of psychiatry. Supplement, 1998, Issue:35

    Topics: Biogenic Monoamines; Fenfluramine; Humans; Neuropeptides; Obsessive-Compulsive Disorder; Piperazines; Pyrazines; Pyrimidines; Serotonin; Serotonin Syndrome; Synaptic Transmission; Tryptophan

1998
The effects of tryptophan depletion on mood and psychiatric symptoms.
    Journal of affective disorders, 2001, Volume: 64, Issue:2-3

    Topics: Anorexia Nervosa; Bipolar Disorder; Brain; Bulimia; Cognition Disorders; Depressive Disorder, Major; Humans; Mood Disorders; Obsessive-Compulsive Disorder; Recurrence; Serotonin; Severity of Illness Index; Substance-Related Disorders; Tryptophan

2001
Neuroendocrine challenge tests: assessment of 5-HT function in anxiety and depression.
    Molecular aspects of medicine, 1992, Volume: 13, Issue:3

    Topics: Anxiety; Depression; Humans; Neurosecretory Systems; Obsessive-Compulsive Disorder; Panic Disorder; Serotonin; Synapses; Tryptophan

1992

Trials

13 trial(s) available for tryptophan and Obsessive-Compulsive Disorder

ArticleYear
Effects of tryptophan depletion on selective serotonin reuptake inhibitor-remitted patients with obsessive compulsive disorder.
    Journal of psychopharmacology (Oxford, England), 2017, Volume: 31, Issue:12

    Topics: Adolescent; Adult; Aged; Anxiety; Blood Pressure; Double-Blind Method; Female; Humans; Male; Middle Aged; Obsessive-Compulsive Disorder; Psychiatric Status Rating Scales; Remission Induction; Selective Serotonin Reuptake Inhibitors; Self-Control; Thinking; Tryptophan; Visual Analog Scale; Young Adult

2017
Platelet serotonergic predictors of clinical improvement in obsessive compulsive disorder.
    Journal of clinical psychopharmacology, 2004, Volume: 24, Issue:1

    Topics: Adolescent; Adult; Binding Sites; Biomarkers; Blood Platelets; Carrier Proteins; Cell Membrane; Child; Diet; Female; France; Humans; Imipramine; Inositol Phosphates; Iodine Isotopes; Lysergic Acid Diethylamide; Male; Membrane Glycoproteins; Membrane Transport Proteins; Middle Aged; Nerve Tissue Proteins; Obsessive-Compulsive Disorder; Paroxetine; Psychiatric Status Rating Scales; Radiochemistry; Receptor, Serotonin, 5-HT2A; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins; Treatment Outcome; Tritium; Tryptophan

2004
Impact of experimentally induced serotonin deficiency by tryptophan depletion on saliva cortisol concentrations.
    Pharmacopsychiatry, 2005, Volume: 38, Issue:2

    Topics: Adult; Cross-Over Studies; Depressive Disorder; Double-Blind Method; Female; Humans; Hydrocortisone; Hypothalamo-Hypophyseal System; Male; Obsessive-Compulsive Disorder; Pituitary-Adrenal System; Psychometrics; Saliva; Serotonin; Sleep Initiation and Maintenance Disorders; Tryptophan

2005
Lack of effects on core obsessive-compulsive symptoms of tryptophan depletion during symptom provocation in remitted obsessive-compulsive disorder patients.
    Biological psychiatry, 2006, May-01, Volume: 59, Issue:9

    Topics: Adult; Analysis of Variance; Cognitive Behavioral Therapy; Double-Blind Method; Female; Humans; Male; Obsessive-Compulsive Disorder; Psychiatric Status Rating Scales; Secondary Prevention; Selective Serotonin Reuptake Inhibitors; Treatment Outcome; Tryptophan

2006
Effects of tryptophan depletion on cognitive functioning, obsessive-compulsive symptoms and mood in obsessive-compulsive disorder: preliminary results.
    Neuropsychobiology, 2007, Volume: 56, Issue:2-3

    Topics: Adult; Affect; Anxiety; Cognition; Cross-Over Studies; Depression; Double-Blind Method; Female; Food, Formulated; Humans; Male; Neuropsychological Tests; Obsessive-Compulsive Disorder; Psychiatric Status Rating Scales; Selective Serotonin Reuptake Inhibitors; Statistics, Nonparametric; Tryptophan

2007
Lithium and tryptophan augmentation in clomipramine-resistant obsessive-compulsive disorder.
    The American journal of psychiatry, 1984, Volume: 141, Issue:10

    Topics: Adult; Clinical Trials as Topic; Clomipramine; Double-Blind Method; Drug Therapy, Combination; Humans; Lithium; Lithium Carbonate; Male; Obsessive-Compulsive Disorder; Psychiatric Status Rating Scales; Tryptophan

1984
Neuroendocrine responses to intravenous L-tryptophan in obsessive compulsive disorder.
    Journal of affective disorders, 1994, Volume: 32, Issue:2

    Topics: Adolescent; Adult; Arousal; Female; Growth Hormone; Humans; Male; Middle Aged; Obsessive-Compulsive Disorder; Prolactin; Receptors, Serotonin; Reference Values; Tryptophan

1994
Tryptophan depletion in patients with obsessive-compulsive disorder who respond to serotonin reuptake inhibitors.
    Archives of general psychiatry, 1994, Volume: 51, Issue:4

    Topics: Adult; Amino Acids; Brain; Brain Chemistry; Depression, Chemical; Diet; Double-Blind Method; Female; Humans; Male; Middle Aged; Obsessive-Compulsive Disorder; Personality Inventory; Placebos; Psychiatric Status Rating Scales; Selective Serotonin Reuptake Inhibitors; Serotonin; Tryptophan

1994
Tryptophan depletion in obsessive-compulsive patients.
    Biological psychiatry, 1996, Sep-01, Volume: 40, Issue:5

    Topics: Adult; Affect; Amino Acids; Amino Acids, Essential; Cross-Over Studies; Double-Blind Method; Female; Humans; Male; Obsessive-Compulsive Disorder; Psychiatric Status Rating Scales; Tryptophan

1996
A preliminary study of tryptophan depletion on tics, obsessive-compulsive symptoms, and mood in Tourette's syndrome.
    Biological psychiatry, 1997, Jan-01, Volume: 41, Issue:1

    Topics: Adult; Affect; Double-Blind Method; Female; Humans; Male; Middle Aged; Neurologic Examination; Obsessive-Compulsive Disorder; Serotonin; Tourette Syndrome; Tryptophan

1997
Studies of endocrine activity, plasma tryptophan and catecholamine excretion on psychosurgical patients.
    Acta psychiatrica Scandinavica, 1977, Volume: 56, Issue:1

    Topics: Adult; Anxiety; Clinical Trials as Topic; Depression; Dexamethasone; Epinephrine; Female; Humans; Hydrocortisone; Middle Aged; Norepinephrine; Obsessive-Compulsive Disorder; Personality Inventory; Psychosurgery; Tryptophan

1977
L-tryptophan in obsessive-compulsive disorders.
    The American journal of psychiatry, 1977, Volume: 134, Issue:11

    Topics: Adolescent; Adult; Aggression; Clinical Trials as Topic; Drug Evaluation; Female; Humans; Male; Obsessive-Compulsive Disorder; Remission, Spontaneous; Tryptophan

1977
L-tryptophan in affective disorders: indoleamine changes and differential clinical effects.
    Psychopharmacologia, 1974, Jan-09, Volume: 34, Issue:1

    Topics: Affective Symptoms; Blood Platelets; Clinical Trials as Topic; Depression; Humans; Hydroxyindoleacetic Acid; Indoles; Obsessive-Compulsive Disorder; Placebos; Probenecid; Serotonin; Sleep; Tryptophan

1974

Other Studies

20 other study(ies) available for tryptophan and Obsessive-Compulsive Disorder

ArticleYear
Amelioration of obsessive-compulsive disorder in three mouse models treated with one epigenetic drug: unraveling the underlying mechanism.
    Scientific reports, 2019, 06-19, Volume: 9, Issue:1

    Topics: Animals; Compulsive Behavior; Disease Models, Animal; DNA Methylation; Epigenesis, Genetic; Female; Humans; Male; Mice; Obsessive-Compulsive Disorder; Phthalimides; Tryptophan

2019
Brain regional α-[11C]methyl-L-tryptophan trapping in medication-free patients with obsessive-compulsive disorder.
    Archives of general psychiatry, 2011, Volume: 68, Issue:7

    Topics: Adolescent; Adult; Brain; Case-Control Studies; Caudate Nucleus; Female; Hippocampus; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Obsessive-Compulsive Disorder; Positron-Emission Tomography; Temporal Lobe; Tryptophan; Young Adult

2011
Hypothalamic digoxin deficiency in obsessive compulsive disorder and la Tourette's syndrome.
    The International journal of neuroscience, 2002, Volume: 112, Issue:7

    Topics: Cholesterol; Digoxin; Dolichols; Dominance, Cerebral; Erythrocyte Membrane; Functional Laterality; Glycosaminoglycans; Humans; Hydroxymethylglutaryl CoA Reductases; Hypothalamus; Obsessive-Compulsive Disorder; Polyisoprenyl Phosphates; Signal Transduction; Sodium-Potassium-Exchanging ATPase; Tourette Syndrome; Tryptophan; Tyrosine

2002
Familial hypothalamic digoxin deficiency syndrome.
    The Journal of neuropsychiatry and clinical neurosciences, 2004,Winter, Volume: 16, Issue:1

    Topics: Body Mass Index; Brain Chemistry; Depressive Disorder, Major; Digoxin; Dolichols; Dominance, Cerebral; Erythrocytes; Family Health; Female; Glycosaminoglycans; Humans; Hydroxymethylglutaryl CoA Reductases; Hypertension; Hypothalamic Diseases; Male; Obsessive-Compulsive Disorder; Osteoporosis; Respiration Disorders; Sexual Dysfunction, Physiological; Sodium-Potassium-Exchanging ATPase; Tics; Tryptophan; Tyrosine

2004
Sleep in obsessive compulsive disorder: polysomnographic studies under baseline conditions and after experimentally induced serotonin deficiency.
    European archives of psychiatry and clinical neuroscience, 2007, Volume: 257, Issue:3

    Topics: Adult; Aging; Electroencephalography; Female; Humans; Male; Middle Aged; Obsessive-Compulsive Disorder; Polysomnography; Psychiatric Status Rating Scales; Serotonin; Sleep; Sleep Stages; Sleep, REM; Tryptophan

2007
A W148R mutation in the human FOXD4 gene segregating with dilated cardiomyopathy, obsessive-compulsive disorder, and suicidality.
    International journal of molecular medicine, 2007, Volume: 19, Issue:3

    Topics: Adult; Amino Acid Sequence; Arginine; Base Sequence; Cardiomyopathy, Dilated; Chromosome Segregation; DNA Mutational Analysis; Fatal Outcome; Forkhead Transcription Factors; Humans; Male; Middle Aged; Molecular Sequence Data; Mutation; Obsessive-Compulsive Disorder; Pedigree; Suicide; Tryptophan

2007
Elevated cerebrospinal fluid levels of oxytocin in obsessive-compulsive disorder. Comparison with Tourette's syndrome and healthy controls.
    Archives of general psychiatry, 1994, Volume: 51, Issue:10

    Topics: Adolescent; Adult; Age of Onset; Arginine Vasopressin; Biogenic Amines; Comorbidity; Dynorphins; Family; Female; Humans; Hydroxyindoleacetic Acid; Male; Mental Disorders; Middle Aged; Obsessive-Compulsive Disorder; Oxytocin; Psychiatric Status Rating Scales; Severity of Illness Index; Tourette Syndrome; Tryptophan

1994
Sequential administration of augmentation strategies in treatment-resistant obsessive-compulsive disorder: preliminary findings.
    International clinical psychopharmacology, 1996, Volume: 11, Issue:1

    Topics: Adrenergic beta-Antagonists; Adult; Buspirone; Depression; Drug Resistance; Drug Therapy, Combination; Female; Humans; Male; Obsessive-Compulsive Disorder; Pindolol; Selective Serotonin Reuptake Inhibitors; Serotonin Receptor Agonists; Tryptophan

1996
Plasma tryptophan levels and tryptophan/neutral amino acid ratios in obsessive-compulsive patients with and without depression.
    Psychiatry research, 1997, Mar-03, Volume: 69, Issue:1

    Topics: Adult; Depressive Disorder; Female; Fluvoxamine; Humans; Male; Middle Aged; Obsessive-Compulsive Disorder; Retrospective Studies; Selective Serotonin Reuptake Inhibitors; Tryptophan

1997
The tryptophan depletion test. Impact on sleep in healthy subjects and patients with obsessive-compulsive disorder.
    Advances in experimental medicine and biology, 1999, Volume: 467

    Topics: Adult; Diet, Protein-Restricted; Electroencephalography; Eye Movements; Female; Humans; Male; Obsessive-Compulsive Disorder; Polysomnography; Psychometrics; Reference Values; Sleep; Sleep Stages; Sleep, REM; Tryptophan

1999
Precursors and metabolites of 5-hydroxytryptamine and dopamine in the ventricular cerebrospinal fluid of psychiatric patients.
    Psychological medicine, 1976, Volume: 6, Issue:3

    Topics: Adult; Aged; Anxiety Disorders; Brain Diseases; Cerebral Ventricles; Depression; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Male; Mental Disorders; Middle Aged; Obsessive-Compulsive Disorder; Phenylacetates; Schizophrenia; Tryptophan; Tyrosine

1976
Acute exacerbation of body dysmorphic disorder during tryptophan depletion.
    The American journal of psychiatry, 1992, Volume: 149, Issue:10

    Topics: Acute Disease; Adult; Body Image; Buspirone; Clomipramine; Delusions; Female; Humans; Neurotransmitter Uptake Inhibitors; Obsessive-Compulsive Disorder; Serotonin; Tryptophan

1992
Plasma tryptophan levels and plasma tryptophan/neutral amino acids ratio in patients with mood disorder, patients with obsessive-compulsive disorder, and normal subjects.
    Psychiatry research, 1992, Volume: 44, Issue:2

    Topics: Adolescent; Adult; Aged; Amino Acids; Bipolar Disorder; Blood-Brain Barrier; Depressive Disorder; Female; Humans; Male; Middle Aged; Obsessive-Compulsive Disorder; Serotonin; Tryptophan

1992
Restless legs syndrome induced by lithium.
    Biological psychiatry, 1991, Dec-01, Volume: 30, Issue:11

    Topics: Adolescent; Dose-Response Relationship, Drug; Humans; Lithium; Male; Methoxyhydroxyphenylglycol; Neurologic Examination; Obsessive-Compulsive Disorder; Restless Legs Syndrome; Tryptophan

1991
A case of obsessive-compulsive disorder related to AIDS: psychopharmacologic treatment.
    Canadian journal of psychiatry. Revue canadienne de psychiatrie, 1991, Volume: 36, Issue:2

    Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS Serodiagnosis; Clomipramine; Delusions; Dose-Response Relationship, Drug; Drug Therapy, Combination; Fear; Humans; Lithium; Male; Obsessive-Compulsive Disorder; Sick Role; Tryptophan

1991
Hypothesis: homozygosity in Tourette syndrome.
    American journal of medical genetics, 1989, Volume: 34, Issue:3

    Topics: Adult; Attention Deficit Disorder with Hyperactivity; Child; Epistasis, Genetic; Female; Genetic Linkage; Homozygote; Humans; Male; Mental Disorders; Obsessive-Compulsive Disorder; Panic; Pedigree; Serotonin; Substance-Related Disorders; Tic Disorders; Tourette Syndrome; Tryptophan

1989
Serotonin function in obsessive-compulsive disorder. A comparison of the effects of tryptophan and m-chlorophenylpiperazine in patients and healthy subjects.
    Archives of general psychiatry, 1988, Volume: 45, Issue:2

    Topics: Adult; Female; Growth Hormone; Humans; Hydrocortisone; Male; Obsessive-Compulsive Disorder; Personality Inventory; Piperazines; Prolactin; Psychiatric Status Rating Scales; Receptors, Serotonin; Serotonin; Sex Factors; Tryptophan

1988
Toxic reaction following the combined administration of fluoxetine and L-tryptophan: five case reports.
    Biological psychiatry, 1986, Volume: 21, Issue:11

    Topics: Adult; Akathisia, Drug-Induced; Arrhythmias, Cardiac; Drug Interactions; Female; Fluoxetine; Humans; Male; Middle Aged; Movement Disorders; Muscle Cramp; Nausea; Obsessive-Compulsive Disorder; Propylamines; Tryptophan

1986
A pilot study of combined trazodone and tryptophan in obsessive-compulsive disorder.
    International clinical psychopharmacology, 1986, Volume: 1, Issue:2

    Topics: Adolescent; Adult; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Obsessive-Compulsive Disorder; Serotonin; Trazodone; Tryptophan

1986
Hyperdopaminergic states: a continuum.
    Lancet (London, England), 1972, Dec-09, Volume: 2, Issue:7789

    Topics: Dihydroxyphenylalanine; Haloperidol; Humans; Obsessive-Compulsive Disorder; Physostigmine; Tryptophan

1972