tryptophan and Neurodegenerative Diseases

tryptophan has been researched along with Neurodegenerative Diseases in 29 studies

Research

Studies (29)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	8 (27.59)	29.6817
2010's	11 (37.93)	24.3611
2020's	10 (34.48)	2.80

Authors

Authors	Studies
Dsouza, HS; Joshi, MB; Mumbrekar, KD; Narasimhamurthy, RK; Rodrigues, JA	1
Aaseth, JO; Alexander, J; Hestad, K; Rootwelt, H	1
Chen, L; Chen, Y; Li, H; Sun, D; Xiang, K; Yang, Y; Zhang, J	1
Buelow, KL; Chinnaiyan, P; Kant, S; Kesarwani, P; Miller, CR; Prabhu, A; Zhao, Y	1
Castro-Portuguez, R; Sutphin, GL	1
Tanaka, M; Toldi, J; Vécsei, L	1
Tanaka, M; Török, N; Vécsei, L	1
Hu, Y; Ji, X; Lv, H; Peng, B; Wang, J; Wang, S; Yin, J; Yu, Z; Zhang, B	1
Bencsik, K; Fricska-Nagy, Z; Sandi, D; Vécsei, L	1
Parasram, K	1
Craddock, TJA; Kurian, P; Obisesan, TO	1
Fallarino, F; Nollen, EAA; Opitz, CA; Platten, M; Röhrig, UF	1
Barone, P	1
Savitz, J	1
Anderson, G; Berk, M; Kubera, M; Maes, M	1
Giorgini, F; Maddison, DC	1
Fülöp, F; Klivényi, P; Szalárdy, L; Toldi, J; Vécsei, L; Veres, G; Zádori, D	1
Fülöp, F; Klivényi, P; Toldi, J; Vámos, E; Vécsei, L; Zádori, D	1
Fulop, F; Klivenyi, P; Szalardy, L; Toldi, J; Vecsei, L; Zadori, D	1
BaHammam, AS; Bharti, VK; Brown, GM; Cardinali, DP; Hardeland, R; Kaur, C; Pandi-Perumal, SR; Spence, DW	1
Tan, L; Yu, JT	1
Fülöp, F; Szalárdy, L; Toldi, J; Vécsei, L	1
Kurup, PA; Kurup, RK	1
Coyle, JT	1
Browndyke, J; Ghio, A; Schmechel, DE	1
Forouhar, F; Khan, JA; Tao, X; Tong, L	1
Darlington, LG; Forrest, CM; Mackay, GM; Stone, TW; Stoy, N	1
Groves, P; Palczewska, M	1
Daya, S; Parmar, P	1

Reviews

22 review(s) available for tryptophan and Neurodegenerative Diseases

Article	Year
Pesticides Exposure-Induced Changes in Brain Metabolome: Implications in the Pathogenesis of Neurodegenerative Disorders. Neurotoxicity research, 2022, Volume: 40, Issue:5 Topics: Animals; Biomarkers; Brain; Dopamine; Fatty Acids; Glutathione; Humans; Metabolome; Neurodegenerative Diseases; Pesticides; Tryptophan	2022
The Role of Tryptophan Dysmetabolism and Quinolinic Acid in Depressive and Neurodegenerative Diseases. Biomolecules, 2022, 07-18, Volume: 12, Issue:7 Topics: Cytokines; Humans; Kynurenine; Neurodegenerative Diseases; Quinolinic Acid; Tryptophan	2022
Kynurenine-3-monooxygenase (KMO): From its biological functions to therapeutic effect in diseases progression. Journal of cellular physiology, 2022, Volume: 237, Issue:12 Topics: Disease Progression; Humans; Kynurenic Acid; Kynurenine; Kynurenine 3-Monooxygenase; Neurodegenerative Diseases; Tryptophan	2022
Kynurenine pathway, NAD Experimental gerontology, 2020, Volume: 132 Topics: Aging; Animals; Brain; Humans; Kynurenine; Longevity; Metabolic Networks and Pathways; Mice; Mitochondria; Mitophagy; NAD; Neurodegenerative Diseases; Oxidation-Reduction; Oxidative Stress; Tryptophan	2020
Exploring the Etiological Links behind Neurodegenerative Diseases: Inflammatory Cytokines and Bioactive Kynurenines. International journal of molecular sciences, 2020, Mar-31, Volume: 21, Issue:7 Topics: Alzheimer Disease; Anti-Inflammatory Agents; Biomarkers; Cytokines; Humans; Huntington Disease; Inflammation; Kynurenine; Neurodegenerative Diseases; Parkinson Disease; Reactive Oxygen Species; Tryptophan	2020
Searching for Peripheral Biomarkers in Neurodegenerative Diseases: The Tryptophan-Kynurenine Metabolic Pathway. International journal of molecular sciences, 2020, Dec-08, Volume: 21, Issue:24 Topics: Animals; Biomarkers; Brain; Gastrointestinal Microbiome; Humans; Kynurenine; Neurodegenerative Diseases; Tryptophan	2020
Neurodegeneration in Multiple Sclerosis: Symptoms of Silent Progression, Biomarkers and Neuroprotective Therapy-Kynurenines Are Important Players. Molecules (Basel, Switzerland), 2021, Jun-05, Volume: 26, Issue:11 Topics: Animals; Biomarkers; Disease Progression; Humans; Kynurenine; Molecular Targeted Therapy; Multiple Sclerosis; Neurodegenerative Diseases; Signal Transduction; Tryptophan	2021
Phytochemical treatments target kynurenine pathway induced oxidative stress. Redox report : communications in free radical research, 2018, Volume: 23, Issue:1 Topics: Animals; Disease Models, Animal; Glutamic Acid; Humans; Kynurenine; Neurodegenerative Diseases; Neuroprotective Agents; Oxidative Stress; Phytochemicals; Plant Extracts; Quinolinic Acid; Tryptophan	2018
Tryptophan metabolism as a common therapeutic target in cancer, neurodegeneration and beyond. Nature reviews. Drug discovery, 2019, Volume: 18, Issue:5 Topics: Animals; Antineoplastic Agents; Clinical Trials as Topic; Humans; Metabolic Networks and Pathways; Neoplasms; Neurodegenerative Diseases; Tryptophan	2019
The 'Yin' and the 'Yang' of the kynurenine pathway: excitotoxicity and neuroprotection imbalance in stress-induced disorders. Behavioural pharmacology, 2019, Volume: 30, Issue:2 and 3-Sp Topics: Animals; Brain; Cytokines; Depressive Disorder, Major; Excitatory Amino Acid Agents; Humans; Hypothalamo-Hypophyseal System; Inflammation; Kynurenine; Neurodegenerative Diseases; Neuroprotection; Pituitary-Adrenal System; Tryptophan	2019
The kynurenine pathway: a finger in every pie. Molecular psychiatry, 2020, Volume: 25, Issue:1 Topics: Aging; Animals; Energy Metabolism; Humans; Kynurenine; Mental Disorders; NAD; Neurodegenerative Diseases; Signal Transduction; Tryptophan	2020
Targeting classical IL-6 signalling or IL-6 trans-signalling in depression? Expert opinion on therapeutic targets, 2014, Volume: 18, Issue:5 Topics: Acute-Phase Reaction; Animals; Antidepressive Agents; Autoimmunity; Bacterial Translocation; Cytokines; Depression; Depressive Disorder; Disease Models, Animal; Genetic Predisposition to Disease; Humans; Hypothalamo-Hypophyseal System; Inflammation; Interleukin-6; Meta-Analysis as Topic; Molecular Targeted Therapy; Neurodegenerative Diseases; Neuroimmunomodulation; Neurotransmitter Agents; Pituitary-Adrenal System; Receptors, Interleukin-6; Signal Transduction; Stress, Psychological; T-Lymphocyte Subsets; Tryptophan; Zinc	2014
The kynurenine pathway and neurodegenerative disease. Seminars in cell & developmental biology, 2015, Volume: 40 Topics: Animals; Humans; Kynurenine; Metabolic Networks and Pathways; Neurodegenerative Diseases; Tryptophan	2015
Inhibitors of the kynurenine pathway as neurotherapeutics: a patent review (2012-2015). Expert opinion on therapeutic patents, 2016, Volume: 26, Issue:7 Topics: Animals; Central Nervous System Neoplasms; Cognition Disorders; Drug Design; Enzyme Inhibitors; Humans; Kynurenine; Neurodegenerative Diseases; Patents as Topic; Structure-Activity Relationship; Tryptophan	2016
Kynurenines in chronic neurodegenerative disorders: future therapeutic strategies. Journal of neural transmission (Vienna, Austria : 1996), 2009, Volume: 116, Issue:11 Topics: Animals; Brain; Glutamic Acid; Humans; Kynurenic Acid; Mitochondrial Diseases; NAD; Neurodegenerative Diseases; Neuroprotective Agents; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Quinolinic Acid; Tryptophan	2009
Mitochondrial disturbances, tryptophan metabolites and neurodegeneration: medicinal chemistry aspects. Current medicinal chemistry, 2012, Volume: 19, Issue:13 Topics: Animals; Chemistry, Pharmaceutical; Humans; Kynurenine; Mitochondria; Neurodegenerative Diseases; Tryptophan	2012
Melatonin antioxidative defense: therapeutical implications for aging and neurodegenerative processes. Neurotoxicity research, 2013, Volume: 23, Issue:3 Topics: Aging; Animals; Antioxidants; Apoptosis; Brain Injuries; Circadian Rhythm; Clinical Trials as Topic; Double-Blind Method; Drug Evaluation, Preclinical; Free Radicals; Homeostasis; Humans; Light; Melatonin; Mice; Mice, Transgenic; Mitochondria; Multicenter Studies as Topic; Nerve Tissue Proteins; Neurodegenerative Diseases; Neurons; Neuroprotective Agents; Oxidative Stress; Pineal Gland; Sleep Initiation and Maintenance Disorders; Tryptophan	2013
The kynurenine pathway in neurodegenerative diseases: mechanistic and therapeutic considerations. Journal of the neurological sciences, 2012, Dec-15, Volume: 323, Issue:1-2 Topics: Aging; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Animals; Enzyme Inhibitors; Humans; Huntington Disease; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inflammation; Kynurenic Acid; Kynurenine; Microglia; Molecular Targeted Therapy; Neurodegenerative Diseases; Neurons; Neuroprotective Agents; Neurotoxins; Parkinson Disease; Quinolinic Acid; Receptors, G-Protein-Coupled; Receptors, N-Methyl-D-Aspartate; Tryptophan	2012
Kynurenines in the CNS: recent advances and new questions. Nature reviews. Drug discovery, 2013, Volume: 12, Issue:1 Topics: Animals; Autoimmune Diseases; Central Nervous System Diseases; Drug Design; Drug Evaluation, Preclinical; Humans; Immune Tolerance; Kynurenine; Migraine Disorders; Neurodegenerative Diseases; Pain; Tryptophan	2013
Glial metabolites of tryptophan and excitotoxicity: coming unglued. Experimental neurology, 2006, Volume: 197, Issue:1 Topics: Animals; Excitatory Amino Acid Agonists; Excitatory Amino Acids; Humans; Kainic Acid; Kynurenine; Mice; Mice, Knockout; Neurodegenerative Diseases; Neuroglia; Receptors, N-Methyl-D-Aspartate; Tryptophan	2006
Nicotinamide adenine dinucleotide metabolism as an attractive target for drug discovery. Expert opinion on therapeutic targets, 2007, Volume: 11, Issue:5 Topics: Acrylamides; Adenosine Diphosphate Ribose; Aging; Animals; Antineoplastic Agents; Autoimmune Diseases; Clinical Trials, Phase II as Topic; Cyclic ADP-Ribose; DNA Damage; Drug Design; Enzyme Inhibitors; Humans; Kynurenine; Mice; NAD; Neoplasms; Neurodegenerative Diseases; Neuroprotective Agents; Piperidines; Poly Adenosine Diphosphate Ribose; Signal Transduction; Sirtuins; Tryptophan	2007
Tryptophan, adenosine, neurodegeneration and neuroprotection. Metabolic brain disease, 2007, Volume: 22, Issue:3-4 Topics: Adenosine; Animals; Hepatic Encephalopathy; Humans; Kynurenine; NAD; Neurodegenerative Diseases; Neuroprotective Agents; Oxidative Stress; Quinolinic Acid; Receptors, N-Methyl-D-Aspartate; Receptors, Purinergic P1; Tryptophan	2007

Other Studies

7 other study(ies) available for tryptophan and Neurodegenerative Diseases

Article	Year
Quinolinate promotes macrophage-induced immune tolerance in glioblastoma through the NMDAR/PPARγ signaling axis. Nature communications, 2023, 03-16, Volume: 14, Issue:1 Topics: Animals; Biological Products; Brain Neoplasms; Glioblastoma; Immune Tolerance; Macrophages; Mice; Neurodegenerative Diseases; PPAR gamma; Quinolinic Acid; Receptors, N-Methyl-D-Aspartate; Tryptophan; Tumor Microenvironment	2023
Ameliorative Effect of Dietary Tryptophan on Neurodegeneration and Inflammation in d-Galactose-Induced Aging Mice with the Potential Mechanism Relying on AMPK/SIRT1/PGC-1α Pathway and Gut Microbiota. Journal of agricultural and food chemistry, 2021, Apr-28, Volume: 69, Issue:16 Topics: Aging; AMP-Activated Protein Kinases; Animals; Diet; Galactose; Gastrointestinal Microbiome; Inflammation; Mice; Neurodegenerative Diseases; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha; Sirtuin 1; Tryptophan	2021
Oxidative species-induced excitonic transport in tubulin aromatic networks: Potential implications for neurodegenerative disease. Journal of photochemistry and photobiology. B, Biology, 2017, Volume: 175 Topics: Amyloid beta-Peptides; Cytoskeleton; Humans; Mitochondria; Molecular Dynamics Simulation; Neurodegenerative Diseases; Oxidative Stress; Photons; Protein Structure, Tertiary; Quantum Theory; Reactive Oxygen Species; Signal Transduction; tau Proteins; Tryptophan; Tubulin	2017
Endogenous strychnine: description of hypo- and hyperstrychninergic state in relation to neuropsychiatric diseases. The International journal of neuroscience, 2002, Volume: 112, Issue:10 Topics: Adult; Cell Membrane; Chromatography, High Pressure Liquid; Erythrocytes; Humans; Ions; Male; Middle Aged; Neurodegenerative Diseases; Ouabain; Strychnine; Tryptophan	2002
Strategies for dissecting genetic-environmental interactions in neurodegenerative disorders. Neurotoxicology, 2006, Volume: 27, Issue:5 Topics: Adult; Age Factors; Age of Onset; Aged; Aged, 80 and over; Aging; alpha 1-Antitrypsin; Analysis of Variance; Apolipoprotein E4; Apolipoproteins E; Chi-Square Distribution; Cysteine; DNA Mutational Analysis; Environment; Female; Gene Frequency; Genetic Predisposition to Disease; Hemochromatosis; Humans; Male; Middle Aged; Mutation; Neurodegenerative Diseases; Phenotype; Retrospective Studies; Tryptophan	2006
Cation binding properties of calretinin, an EF-hand calcium-binding protein. Acta biochimica Polonica, 2001, Volume: 48, Issue:1 Topics: Animals; Binding, Competitive; Cadmium; Calbindin 2; Calcium; Cations; Dose-Response Relationship, Drug; Electron Spin Resonance Spectroscopy; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Manganese; Neurodegenerative Diseases; Protein Binding; Rats; S100 Calcium Binding Protein G; Spectrometry, Fluorescence; Terbium; Tryptophan	2001
The effect of copper on (3H)-tryptophan metabolism in organ cultures of rat pineal glands. Metabolic brain disease, 2001, Volume: 16, Issue:3-4 Topics: Animals; Copper; Free Radicals; Indoles; Male; Melatonin; Neurodegenerative Diseases; Organ Culture Techniques; Pineal Gland; Rats; Rats, Wistar; Tryptophan	2001