tryptophan and Nervous System Disorders

tryptophan has been researched along with Nervous System Disorders in 40 studies

Research

Studies (40)

TimeframeStudies, this research(%)All Research%
pre-199013 (32.50)18.7374
1990's12 (30.00)18.2507
2000's5 (12.50)29.6817
2010's6 (15.00)24.3611
2020's4 (10.00)2.80

Authors

AuthorsStudies
Brew, BJ; Guillemin, GJ; Heng, B; Krishnamurthy, S; Pires, AS; Sundaram, G1
Kozieł, K; Urbanska, EM1
Andrews, PI; Antony, J; Ardern-Holmes, S; Bandodkar, S; Chung, J; Dale, RC; Farrar, MA; Gill, D; Guillemin, GJ; Guller, A; Gupta, S; Han, VX; Heng, B; Jones, HF; Kandula, T; Keating, BA; Kothur, K; Menezes, MP; Mohammad, S; Patel, S; Pillai, SC; Sampaio, H; Tantsis, E; Troedson, C; Webster, R; Yan, J1
Alves-Filho, JC; Costa, VV; Cunha, TM; Dantzer, R; Marim, FM; Queiroz-Junior, CM; Teixeira, AL; Teixeira, DC; Teixeira, MM; Valiate, BVS1
Davis, I; Liu, A1
King, NJ; Terentis, AC; Thomas, SR; Yeung, AW1
Fujigaki, H; Saito, K; Yamamoto, Y1
Brew, BJ; Guillemin, GJ; Jacobs, K; Lennon, MJ; Lim, CK; Lovelace, MD; Sundaram, G; Varney, B1
Alexander, J; Brett, R; Henriquez, SA; Pratt, J; Roberts, CW1
Oxenkrug, GF1
Krzyściak, W1
HANSEN, S; HESTRIN, M; MACINTYRE, L; PERRY, TL1
Kurup, PA; Kurup, RK1
Favaron, E; Hafizi, S1
Hefti, F; Melamed, E; Wurtman, RJ1
Härkönen, M; Koskiniemi, ML; Laakso, JT; Wahlroos, O1
Freundlich, E; Statter, M; Yatziv, S1
Correia, MA; Litman, DA1
Fuchs, D; Gasse, T; Meyersbach, P; Murr, C; Schmutzhard, E; Wachter, H1
Mousseau, DD1
Yuki, N1
Curzon, G1
Stone, TW1
Arun, P; Devi, KV; Kurup, PA; Ravikumar, A1
Montini, M; Ongaro, A; Simonutti, M1
Hyyppä, MT; Jolma, T; Kytömäki, O; Långvik, VA; Syvälahti, E1
Fuchs, D; Reibnegger, G; Wachter, H; Weiss, G; Werner-Felmayer, G1
Young, SN1
Boni, RL; Heyes, MP; Markey, SP; Yergey, JA1
Lacour, JP; Ortonne, JP1
Beninger, RJ; Boegman, RJ; Jhamandas, K1
During, MJ; Freese, A; Martin, JB; Swartz, KJ1
Blaivas, M; Feldman, EL; Selwa, JF1
Bowles, CA; Duffy, J; Engel, AG; Gleich, GJ; Lie, JT; Martin, RW; Moyer, TP1
Bammer, HG1
Hamfelt, A; Wetterberg, L1
Milne, MD1
Rauch, H; Siegel, SJ1
Williams, R1
Gamstorp, I; Meeuwisse, G; Tryding, N1

Reviews

16 review(s) available for tryptophan and Nervous System Disorders

ArticleYear
Recent advances in clinical trials targeting the kynurenine pathway.
    Pharmacology & therapeutics, 2022, Volume: 236

    Topics: Humans; Kynurenine; Male; Nervous System Diseases; Quinolinic Acid; Tryptophan

2022
Kynurenine Pathway in Diabetes Mellitus-Novel Pharmacological Target?
    Cells, 2023, 01-31, Volume: 12, Issue:3

    Topics: Animals; Brain; Diabetes Mellitus; Diabetic Retinopathy; Humans; Kynurenine; Nervous System Diseases; Tryptophan

2023
Role of indoleamine 2,3-dioxygenase in health and disease.
    Clinical science (London, England : 1979), 2015, Volume: 129, Issue:7

    Topics: Animals; Bacterial Infections; Catalysis; Gene Expression Regulation, Enzymologic; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Mice; Models, Biological; Neoplasms; Nervous System Diseases; Oxidation-Reduction; Protein Conformation; Protein Processing, Post-Translational; Signal Transduction; Substrate Specificity; Tryptophan

2015
L-Tryptophan-kynurenine pathway enzymes are therapeutic target for neuropsychiatric diseases: Focus on cell type differences.
    Neuropharmacology, 2017, Volume: 112, Issue:Pt B

    Topics: Animals; Humans; Kynurenine; Metabolic Networks and Pathways; Nervous System Diseases; Tryptophan

2017
Recent evidence for an expanded role of the kynurenine pathway of tryptophan metabolism in neurological diseases.
    Neuropharmacology, 2017, Volume: 112, Issue:Pt B

    Topics: Animals; Humans; Kynurenine; Metabolic Networks and Pathways; Nervous System Diseases; Tryptophan

2017
Neuropsychiatric disease and Toxoplasma gondii infection.
    Neuroimmunomodulation, 2009, Volume: 16, Issue:2

    Topics: Animals; Behavior; Behavior, Animal; Cats; Cytokines; Depression; Dopamine; Female; Host-Parasite Interactions; Humans; Male; Mental Disorders; Mice; Nervous System Diseases; Neurons; Neurosecretory Systems; Protozoan Proteins; Rats; Risk Factors; Schizophrenia; Serotonin; Toxoplasma; Toxoplasmosis; Toxoplasmosis, Animal; Tryptophan

2009
Metabolic syndrome, age-associated neuroendocrine disorders, and dysregulation of tryptophan-kynurenine metabolism.
    Annals of the New York Academy of Sciences, 2010, Volume: 1199

    Topics: Aging; Animals; Endocrine System Diseases; Humans; Kynurenine; Metabolic Syndrome; Nervous System Diseases; Tryptophan

2010
Activity of selected aromatic amino acids in biological systems.
    Acta biochimica Polonica, 2011, Volume: 58, Issue:4

    Topics: Biomarkers; Cardiovascular Diseases; Enzyme Activation; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Levodopa; Melanins; Monophenol Monooxygenase; Nervous System Diseases; Oxidative Stress; Renal Insufficiency, Chronic; Serotonin; Tryptophan; Tyrosine

2011
Interferon-induced depression: mechanisms and management.
    British journal of hospital medicine (London, England : 2005), 2007, Volume: 68, Issue:6

    Topics: Cyclooxygenase 2; Depressive Disorder; Female; Humans; Hypothalamo-Hypophyseal System; Interferon-alpha; Kynurenine; Male; Nervous System Diseases; Tryptophan

2007
Tryptamine: a metabolite of tryptophan implicated in various neuropsychiatric disorders.
    Metabolic brain disease, 1993, Volume: 8, Issue:1

    Topics: Animals; Behavior, Animal; Binding Sites; Chemical Phenomena; Chemistry; Humans; Mental Disorders; Nervous System Diseases; Neurotransmitter Agents; Tissue Distribution; Tryptamines; Tryptophan

1993
Brain tryptophan. Normal and disturbed control.
    Advances in experimental medicine and biology, 1996, Volume: 398

    Topics: Animals; Anorexia; Brain; Depressive Disorder; Feeding and Eating Disorders; Female; Humans; Male; Nervous System Diseases; Serotonin; Tryptophan

1996
Endogenous neurotoxins from tryptophan.
    Toxicon : official journal of the International Society on Toxinology, 2001, Volume: 39, Issue:1

    Topics: Animals; Humans; Kynurenine; Nervous System Diseases; Neurotoxins; Quinolinic Acid; Tryptophan

2001
Mass spectrometric determinations of tryptophan and its metabolites.
    Advances in experimental medicine and biology, 1991, Volume: 294

    Topics: Animals; Body Fluids; Gas Chromatography-Mass Spectrometry; Humans; Mass Spectrometry; Melatonin; Molecular Structure; Nervous System Diseases; Pineal Gland; Quinolinic Acid; Quinolinic Acids; Schizophrenia; Serotonin; Tryptophan

1991
[Myalgia-hypereosinophilia syndrome caused by L-tryptophan].
    Annales de dermatologie et de venereologie, 1990, Volume: 117, Issue:12

    Topics: Adrenal Cortex Hormones; Centers for Disease Control and Prevention, U.S.; Eosinophilia; Humans; Muscular Diseases; Nervous System Diseases; Pain; Pruritus; Scleroderma, Systemic; Syndrome; Tryptophan; United States

1990
Kynurenine metabolites of tryptophan: implications for neurologic diseases.
    Neurology, 1990, Volume: 40, Issue:4

    Topics: Animals; Brain; Humans; Kynurenine; Nervous System Diseases; Tryptophan

1990
[Neurological aspects of the vitamin B complex].
    Zeitschrift fur Neurologie, 1972, Volume: 202, Issue:3

    Topics: Alcoholism; Anticonvulsants; Cyanides; Deficiency Diseases; Electroencephalography; Erythrocytes; Folic Acid Deficiency; Humans; Isoniazid; Nervous System Diseases; Neurocognitive Disorders; Pellagra; Polyneuropathies; Schilling Test; Spinal Cord Diseases; Thiamine Deficiency; Transketolase; Tryptophan; Vitamin B 12; Vitamin B 12 Deficiency; Vitamin B 6 Deficiency; Vitamin B Deficiency; Wernicke Encephalopathy

1972

Trials

1 trial(s) available for tryptophan and Nervous System Disorders

ArticleYear
[Controlled clinical study and clinico-psychological evaluation of a preparation with neurotrophic effects].
    La Clinica terapeutica, 1977, Aug-15, Volume: 82, Issue:3

    Topics: Aged; Arginine; Clinical Trials as Topic; Drug Combinations; Drug Evaluation; Female; Glutamine; Humans; Male; Mental Disorders; Middle Aged; Nervous System Diseases; Organophosphorus Compounds; Serine; Threonine; Tryptophan; Vitamin B 12

1977

Other Studies

23 other study(ies) available for tryptophan and Nervous System Disorders

ArticleYear
CSF neopterin, quinolinic acid and kynurenine/tryptophan ratio are biomarkers of active neuroinflammation.
    EBioMedicine, 2023, Volume: 91

    Topics: Adolescent; Biomarkers; Child; Child, Preschool; Humans; Infant; Inflammation; Kynurenine; Leukocytosis; Male; Neopterin; Nervous System Diseases; Neuroinflammatory Diseases; Quinolinic Acid; Tryptophan

2023
Inhibition of Tryptophan Catabolism Is Associated With Neuroprotection During
    Frontiers in immunology, 2021, Volume: 12

    Topics: Animals; Brain; Cells, Cultured; Disease Models, Animal; Mice; Mice, Inbred C57BL; Microcephaly; Nervous System Diseases; Neuroinflammatory Diseases; Neurons; Neuroprotection; Neuroprotective Agents; Tryptophan; Zika Virus; Zika Virus Infection

2021
What is the tryptophan kynurenine pathway and why is it important to neurotherapeutics?
    Expert review of neurotherapeutics, 2015, Volume: 15, Issue:7

    Topics: Animals; Humans; Kynurenine; Nervous System Diseases; Signal Transduction; Tryptophan

2015
EXOGENOUS URINARY AMINES OF PLANT ORIGIN.
    Clinica chimica acta; international journal of clinical chemistry, 1965, Volume: 11

    Topics: 5-Hydroxytryptophan; Amines; Benzaldehydes; Biomedical Research; Chromatography; Coffee; Condiments; Diet; Fruit; Hydroxyindoleacetic Acid; Indoleacetic Acids; Metabolism; Mustard Plant; Nervous System Diseases; Plants, Edible; Serotonin; Synephrine; Tea; Tryptophan; Urine

1965
Isoprenoid pathway-related membrane dysfunction in neuropsychiatric disorders.
    The International journal of neuroscience, 2003, Volume: 113, Issue:11

    Topics: Adult; Cholesterol; Digoxin; Dolichols; Erythrocyte Membrane; Female; Humans; Hydroxymethylglutaryl CoA Reductases; Male; Membrane Proteins; Mental Disorders; Middle Aged; Models, Biological; Nervous System Diseases; Neurons; Phospholipids; Sodium-Potassium-Exchanging ATPase; Terpenes; Tryptophan; Tyrosine; Ubiquinone

2003
Precursor control of neurotransmitter synthesis.
    Pharmacological reviews, 1980, Volume: 32, Issue:4

    Topics: Behavior; Choline; Feedback; Humans; Nervous System Diseases; Neurons; Neurotransmitter Agents; Phosphatidylcholines; Synapses; Synaptic Transmission; Tryptophan; Tyrosine

1980
Simultaneous determination of tryptophan and its 5-hydroxy metabolites in human cerebrospinal fluid by reversed phase liquid chromatography with electrochemical detection.
    Scandinavian journal of clinical and laboratory investigation, 1983, Volume: 43, Issue:6

    Topics: 5-Hydroxytryptophan; Chromatography, Liquid; Humans; Hydroxyindoleacetic Acid; Nervous System Diseases; Serotonin; Tryptophan

1983
Familial pellagra-like skin rash with neurological manifestations.
    Archives of disease in childhood, 1981, Volume: 56, Issue:2

    Topics: Adolescent; Humans; Male; Nervous System Diseases; Niacinamide; Pellagra; Skin Diseases; Tryptophan

1981
L-tryptophan: a common denominator of biochemical and neurological events of acute hepatic porphyria?
    Science (New York, N.Y.), 1983, Dec-02, Volume: 222, Issue:4627

    Topics: Animals; Brain; Heme; Liver; Liver Diseases; Male; Nervous System Diseases; Porphyrias; Rats; Rats, Inbred Strains; Serotonin; Tryptophan; Tryptophan Oxygenase

1983
Neopterin production and tryptophan degradation in acute Lyme neuroborreliosis versus late Lyme encephalopathy.
    European journal of clinical chemistry and clinical biochemistry : journal of the Forum of European Clinical Chemistry Societies, 1994, Volume: 32, Issue:9

    Topics: Acute Disease; Adult; Aged; Biopterins; Borrelia Infections; Chromatography, High Pressure Liquid; Female; Humans; Kynurenine; Longitudinal Studies; Male; Middle Aged; Neopterin; Nervous System Diseases; Tryptophan

1994
Tryptophan-immobilized column adsorbs immunoglobulin G anti-GQ1b antibody from Fisher's syndrome: A new approach to treatment.
    Neurology, 1996, Volume: 46, Issue:6

    Topics: Adolescent; Adult; Aged; Ataxia; Autoantibodies; Autoimmune Diseases; Child; Chromatography, Affinity; Enzyme-Linked Immunosorbent Assay; Female; Gangliosides; Humans; Immunoglobulin G; Immunosorbent Techniques; Male; Middle Aged; Nervous System Diseases; Ophthalmoplegia; Plasmapheresis; Polyradiculoneuropathy; Polyvinyl Alcohol; Syndrome; Tryptophan

1996
Endogenous strychnine, nicotine, and morphine--description of hypo and hyper-strychninergic, nicotinergic and morphinergic state in relation to neuropsychiatric diseases.
    Indian journal of experimental biology, 2000, Volume: 38, Issue:6

    Topics: Adult; Alkaloids; Brain Neoplasms; Chromatography, High Pressure Liquid; Erythrocyte Membrane; Glioma; Humans; Male; Mental Disorders; Middle Aged; Morphine; Neoplasm Proteins; Nervous System Diseases; Nicotine; Sodium-Potassium-Exchanging ATPase; Strychnine; Tryptophan; Tyrosine

2000
L-tryptophan and neuroendocrine regulation in neurologic patients: hormone responses to L-tryptophan loading in patients with hypothalamic lesions.
    Psychoneuroendocrinology, 1977, Volume: 2, Issue:4

    Topics: Acromegaly; Adult; Female; Follicle Stimulating Hormone; Growth Hormone; Humans; Hydrocortisone; Hypopituitarism; Hypothalamus; Leucine; Luteinizing Hormone; Male; Middle Aged; Nervous System Diseases; Tryptophan

1977
Immune activation and neuronal injury in AIDS.
    Trends in neurosciences, 1992, Volume: 15, Issue:7

    Topics: Acquired Immunodeficiency Syndrome; HIV-1; Humans; Interferon-gamma; Nervous System Diseases; Neurons; Quinolinic Acid; Quinolinic Acids; Receptors, N-Methyl-D-Aspartate; Serotonin; Tryptophan

1992
Acute effects of meals on brain tryptophan and serotonin in humans.
    Advances in experimental medicine and biology, 1991, Volume: 294

    Topics: Adult; Affect; Amino Acids; Animals; Brain Chemistry; Dietary Carbohydrates; Dietary Proteins; Female; Food; Food Preferences; Humans; Hydroxyindoleacetic Acid; Male; Nervous System Diseases; Rodentia; Serotonin; Tryptophan

1991
Neurotoxicity of tryptophan metabolites.
    Annals of the New York Academy of Sciences, 1990, Volume: 585

    Topics: Animals; Cerebral Cortex; Choline O-Acetyltransferase; Kynurenic Acid; Male; NADP; Nervous System Diseases; Neurons; Picolinic Acids; Pyridines; Quinolinic Acid; Quinolinic Acids; Rats; Rats, Inbred Strains; Tryptophan

1990
Mononeuropathy multiplex in tryptophan-associated eosinophilia-myalgia syndrome.
    Neurology, 1990, Volume: 40, Issue:10

    Topics: Eosinophilia; Humans; Male; Middle Aged; Muscles; Muscular Diseases; Nervous System Diseases; Sural Nerve; Syndrome; Tryptophan

1990
The clinical spectrum of the eosinophilia-myalgia syndrome associated with L-tryptophan ingestion. Clinical features in 20 patients and aspects of pathophysiology.
    Annals of internal medicine, 1990, Jul-15, Volume: 113, Issue:2

    Topics: Adult; Aged; Eosinophilia; Fasciitis; Female; Humans; Hypertension, Pulmonary; Inflammation; Male; Middle Aged; Muscular Diseases; Myocarditis; Nervous System Diseases; Pain; Pain Management; Pulmonary Fibrosis; Tryptophan

1990
Neuropathy in porphyria.
    Lancet (London, England), 1968, Jan-06, Volume: 1, Issue:7532

    Topics: Humans; Nervous System Diseases; Porphyrias; Pyridoxine; Tryptophan; Vitamin B 6 Deficiency

1968
Hartnup disease.
    The Biochemical journal, 1969, Volume: 111, Issue:3

    Topics: Child; Child, Preschool; Female; Hartnup Disease; Humans; Infant; Infant, Newborn; Male; Nervous System Diseases; Niacinamide; Renal Tubular Transport, Inborn Errors; Tryptophan; Vitamin B Deficiency

1969
Aromatic amino acid metabolism in the wabbler-lethal mouse.
    Biochemical genetics, 1969, Volume: 2, Issue:4

    Topics: Aging; Animals; Liver; Mice; Mixed Function Oxygenases; Nervous System Diseases; Phenylalanine; Rodent Diseases; Transaminases; Tryptophan; Tryptophan Oxygenase; Tyrosine; Tyrosine Transaminase

1969
Hepatic encephalopathy.
    Journal of the Royal College of Physicians of London, 1973, Volume: 8, Issue:1

    Topics: Acetaminophen; Ammonia; Animals; Brain; Brain Edema; Diet Therapy; Dopamine; Female; Humans; Lactulose; Liver Diseases; Liver Transplantation; Male; Neomycin; Nervous System Diseases; Parabiosis; Renal Dialysis; Serotonin; Suicide; Swine; Tryptophan

1973
Effect of phenytoin on the tryptophan load test.
    Acta paediatrica Scandinavica, 1968, Volume: 57, Issue:2

    Topics: Adolescent; Age Factors; Child; Child, Preschool; Diagnosis, Differential; Epilepsy; Female; Humans; Infant; Intellectual Disability; Male; Nervous System Diseases; Phenytoin; Pyridoxine; Tryptophan; Vitamin B 6 Deficiency; Xanthurenates

1968