tryptophan and Malignant Melanoma

tryptophan has been researched along with Malignant Melanoma in 49 studies

Research

Studies (49)

TimeframeStudies, this research(%)All Research%
pre-19908 (16.33)18.7374
1990's2 (4.08)18.2507
2000's13 (26.53)29.6817
2010's6 (12.24)24.3611
2020's20 (40.82)2.80

Authors

AuthorsStudies
Allorge, D; Brochez, L; Demeyer, A; Ferdinande, L; Haspeslagh, M; Hennart, B; Meireson, A; Ost, P; Spaas, M; Sundahl, N1
Agami, R; Altelaar, M; Berkers, CR; Bleijerveld, OB; Blommaert, N; Champagne, J; Faller, WJ; Kenski, J; Nagel, R; Pataskar, A; Peeper, DS; Ramalho, S; Wernaart, D; Zaal, EA1
Birková, A; Čižmárová, B; Hubková, B; Mareková, M; Valko-Rokytovská, M; Zábavníková, M1
Conroy, JM; DePietro, P; Fujiwara, Y; Kato, S; Kurzrock, R; Nesline, MK; Pabla, S1
Gerkowicz, A; Krasowska, D; Walczak, K1
Bender, MJ; Bruno, TC; Cannon, N; Cervantes-Barragan, L; Davar, D; Gelhaus, SL; Gocher-Demske, AM; Hinterleitner, R; Joglekar, AV; Laughlin, CR; Lee, STM; McCulloch, JA; McPherson, AC; Medina Sanchez, L; Meisel, M; Mims, TS; Mullett, SJ; Pandey, SP; Phelps, CM; Pierre, JF; Rana, M; Richie, TG; Shapira, JH; Vignali, DAA; Zarour, HM1
Belladonna, ML; Gargaro, M; Mondanelli, G; Orabona, C; Pallotta, MT; Panfili, E; Rossini, S; Suvieri, C; Volpi, C1
Abernethy-Leinwand, A; Bouchard, DM; Collichio, FA; Ezzell, JA; Giglio, BC; Googe, PB; Ivanova, A; Ivanovic, M; Kowalski, MH; Lee, YZ; Li, Z; Long, PK; Meyers, MO; Moschos, SJ; Nikolaishvili-Feinberg, N; Oldan, JD; Ollila, DW; Smith, E; Thomas, NE; Trembath, DG; Wallack, DE; Wong, TZ; Zhao, W1
Li, B; Wang, J; Wei, W; Zhao, T1
Dréno, B; Khammari, A; Knol, AC; Le Naour, S; Pandolfino, MC1
Azimi, A; Baumgartner, R; Hansson, J; Kamleh, MA; Ketelhuth, DFJ; Kiani, NA; Lundqvist, A; Morikawa, H; Rad Pour, S; Shafi, G; Shang, M; Tegnér, J; Wheelock, CE; Yang, M1
Amaro, F; Duarte, D; Fresco, P; Gonçalves, J; Oliveira, JC; Reguengo, H; Silva, D; Silva, I; Vale, N1
Bossé, D; Braun, D; Bullock, K; Choueiri, TK; Clish, CB; Freeman, GJ; Garraway, LA; Giannakis, M; Gopal, S; Gurjao, C; Horak, C; Jin, C; Lalani, AA; Li, H; McDermott, DF; Schreiber, SL; Sellers, WR; Shukla, SA; Signoretti, S; Stephen Hodi, F; Van Allen, EM; Wind-Rotolo, M1
Almquist, DR; Block, MS; Bryce, AH; DeLeon, TT; Dronca, RS; Joseph, RW; Kipp, BR; Kosiorek, HE; Kottschade, LA; Langlais, BT; Mangold, A; Markovic, SN; McWilliams, RR; Rumilla, KM; Seetharam, M; Sekulic, A; Voss, JS; Winters, JL1
Arcisio-Miranda, M; da Silva, AMB; de Almeida, MTG; de Souza, BM; Dos Santos Cabrera, MP; Martins, DB; Pacca, CC; Palma, MS1
Campa, A; Consolaro, MEL; da Costa Souza, P; Faião-Flores, F; Felipe-Silva, A; Maria-Engler, SS; Migliorini, S; Oliveira, EA; Sandri, S; Tiago, M; Vazquez, VL; Watanabe, LRM1
Feng, X; He, X; Li, Y; Qi, D; Shen, X; Xia, X; Zeng, Z; Zhou, Z; Zhu, C1
Baptista, MS; de Faria Lopes, L; Hua, A; Jandova, J; Justiniano, R; Park, SL; Perer, J; Wondrak, GT1
Agami, R; Alon, M; Altelaar, M; Bartok, O; Berkers, CR; Bleijerveld, OB; Brandis, A; Champagne, J; Geiger, T; Goldfarb, E; Hayoun, D; Huang, X; Kenski, J; Körner, PR; Kreuger, IZM; Laos, M; Lebon, S; Levin, Y; Levy, R; Mizrahi, O; Nagel, R; Nielsen, MM; Olweus, J; Pataskar, A; Peeper, DS; Samuels, Y; Stern-Ginossar, N; Wargo, J; Yang, W; Zaal, EA1
Plech, T; Szelest, M; Walczak, K1
Birková, A; Hubková, B; Mareková, M; Valko-Rokytovská, M; Zábavníková, M1
Brincks, EL; Drabick, J; Grossmann, KF; Kennedy, EP; Kolhe, R; Link, CJ; McWilliams, RR; Milhem, M; Munn, D; Pacholczyk, R; Rixe, O; Rossi, GR; Sadek, R; Shaheen, MF; Shen, SS; Smith, CM; Tennant, LL; Vahanian, NN; Yu, J; Zakharia, Y1
Lachota, M; Lennikov, A; Malmberg, KJ; Zagozdzon, R1
Arndt, S; Boskovic, M; Bosserhoff, AK; Dettmer, K; Fadil, F; Gronwald, W; Gruber, M; Karrer, S; Samol, C; Unger, P; Zimmermann, JL1
Schmidt, C1
Cresswell, P; Graham, M; Hee, JS; Leonhardt, RM; Vigneron, N1
Boyle, GM; Brown, DL; Chen, W; Cook, AL; Leonard, JH; Marks, LH; Parsons, PG; Smit, DJ; Stow, JL; Sturm, RA1
Capuron, L; Fuchs, D; Lawson, DH; Miller, AH; Musselman, DL; Nemeroff, CB; Neurauter, G1
Capuron, L; Frick, B; Fuchs, D; Lawson, DH; Miller, AH; Musselman, DL; Nemeroff, CB; Schröcksnadel, K1
Bannink, M; Eggermont, AM; Fekkes, D; Kruit, WH; Mulder, PG; Stoter, G; Van Gool, AR; van Ojik, HH1
Chiarugi, A; Feder-Mengus, C; Frey, DM; Heberer, M; Misteli, H; Oertli, D; Reschner, A; Rosenthal, R; Schumacher, R; Spagnoli, GC; Weber, WP; Zajac, P1
Fuchs, D; Murr, C; Richardsen, L; Weinlich, G; Winkler, C1
Becker, JC; Eggert, AO; Freiwald, M; Houben, R; Kaemmerer, U; Kaempgen, E; Schrama, D; Voigt, H; Wobser, M1
Chen, PW; He, YG; Hogan, N; Mayhew, E; Mellon, JK; Niederkorn, JY; Wang, S1
Bannink, M; Eggermont, AM; Fekkes, D; Hengeveld, MW; Kruit, WH; Sleijfer, S; Stoter, G; van der Holt, B; Van Gool, AR1
Blagoeva, PM1
Allegri, G; Baccichetti, F; Cardin de' Stefani, EL; Costa, C; De Antoni, A; Vanzan, S1
Allegri, G; Bertazzo, A; Costa, CV; Lise, M; Nitti, D1
Hu, DN; McCormick, SA; Roberts, JE1
Chidambaram, A; Fraser, MC; Goldstein, AM; Struewing, JP; Tucker, MA1
Pham, HT; Ruediger, R; Walter, G1
Pisarchik, A; Semak, I; Slominski, A; Sweatman, T; Szczesniewski, A; Wortsman, J1
Campbell, IT; Harvie, MN; Howell, A; Thatcher, N1
Allegri, G; Costa, C; De Antoni, A1
Reynolds, RD1
Gold, J1
Hollins, B; Howard, CH; Rudman, D; Treadwell, PE; Vogler, WR1
Allegri, G; Bordin, F; Costa, C; De Antoni, A1

Reviews

3 review(s) available for tryptophan and Malignant Melanoma

ArticleYear
Indoleamine 2,3-dioxygenase (IDO) inhibitors and cancer immunotherapy.
    Cancer treatment reviews, 2022, Volume: 110

    Topics: B7-H1 Antigen; Class I Phosphatidylinositol 3-Kinases; CTLA-4 Antigen; Enzyme Inhibitors; Humans; Immune Checkpoint Inhibitors; Immunotherapy; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Melanoma; Programmed Cell Death 1 Receptor; Receptors, Aryl Hydrocarbon; Tryptophan; Tryptophan Oxygenase; Tumor Microenvironment

2022
PPARs and the Kynurenine Pathway in Melanoma-Potential Biological Interactions.
    International journal of molecular sciences, 2023, 02-04, Volume: 24, Issue:4

    Topics: Humans; Kynurenine; Melanoma; Peroxisome Proliferator-Activated Receptors; Skin Neoplasms; Tryptophan; Tumor Microenvironment

2023
A New Insight into the Potential Role of Tryptophan-Derived AhR Ligands in Skin Physiological and Pathological Processes.
    International journal of molecular sciences, 2021, Jan-22, Volume: 22, Issue:3

    Topics: Animals; Carbazoles; Chloracne; Dermatitis, Atopic; Humans; Hyperpigmentation; Kynurenic Acid; Kynurenine; Ligands; Melanoma; Mice; Microbiota; Oxidative Stress; Psoriasis; Receptors, Aryl Hydrocarbon; Skin; Skin Diseases; Skin Neoplasms; Skin Physiological Phenomena; Tryptophan; Vitiligo

2021

Trials

5 trial(s) available for tryptophan and Malignant Melanoma

ArticleYear
Strong Dependence between Tryptophan-Related Fluorescence of Urine and Malignant Melanoma.
    International journal of molecular sciences, 2021, Feb-13, Volume: 22, Issue:4

    Topics: Adult; Aged; Female; Fluorescence; Humans; Male; Melanoma; Middle Aged; Neoplasm Staging; Spectrometry, Fluorescence; Tryptophan

2021
Phase II trial of the IDO pathway inhibitor indoximod plus pembrolizumab for the treatment of patients with advanced melanoma.
    Journal for immunotherapy of cancer, 2021, Volume: 9, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Female; Humans; Immunotherapy; Male; Melanoma; Middle Aged; Tryptophan

2021
Interferon-alpha-induced changes in tryptophan metabolism. relationship to depression and paroxetine treatment.
    Biological psychiatry, 2003, Nov-01, Volume: 54, Issue:9

    Topics: Adult; Aged; Antidepressive Agents, Second-Generation; Anxiety; Depression; Double-Blind Method; Female; Humans; Interferon-alpha; Kynurenine; Male; Melanoma; Middle Aged; Neopterin; Paroxetine; Selective Serotonin Reuptake Inhibitors; Time Factors; Tryptophan

2003
Pegylated interferon-alpha2b treatment in melanoma patients: influence on amino acids, 5-hydroxyindolacetic acid and pteridine plasma concentrations.
    Anti-cancer drugs, 2004, Volume: 15, Issue:6

    Topics: Adult; Aged; Amino Acids; Biopterins; Drug Administration Schedule; Female; Humans; Hydroxyindoleacetic Acid; Injections, Subcutaneous; Interferon alpha-2; Interferon-alpha; Male; Melanoma; Middle Aged; Neopterin; Phenylalanine; Pilot Projects; Polyethylene Glycols; Pteridines; Randomized Controlled Trials as Topic; Recombinant Proteins; Time Factors; Tryptophan; Tyrosine

2004
Interferon-alpha influences tryptophan metabolism without inducing psychiatric side effects.
    Neuropsychobiology, 2007, Volume: 55, Issue:3-4

    Topics: Adult; Aged; Behavioral Symptoms; Female; Humans; Immunologic Factors; Interferon-alpha; Male; Melanoma; Middle Aged; Psychiatric Status Rating Scales; Statistics, Nonparametric; Time Factors; Tryptophan

2007

Other Studies

41 other study(ies) available for tryptophan and Malignant Melanoma

ArticleYear
Clinical Relevance of Serum Kyn/Trp Ratio and Basal and IFNγ-Upregulated IDO1 Expression in Peripheral Monocytes in Early Stage Melanoma.
    Frontiers in immunology, 2021, Volume: 12

    Topics: Adult; Cells, Cultured; Enzyme Induction; Female; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferon-gamma; Kynurenine; Male; Melanoma; Middle Aged; Monocytes; Neoplasm Recurrence, Local; Neoplasm Staging; Retrospective Studies; Skin Neoplasms; Time Factors; Treatment Outcome; Tryptophan; Tumor Escape

2021
Oncogene-dependent sloppiness in mRNA translation.
    Molecular cell, 2021, 11-18, Volume: 81, Issue:22

    Topics: Animals; Carcinogenesis; Cell Membrane; Disease Progression; Drug Resistance, Neoplasm; Frameshift Mutation; Frameshifting, Ribosomal; Humans; Immunotherapy; MAP Kinase Signaling System; Melanoma; Mice; Neoplasms; Oncogenes; Peptides; Protein Biosynthesis; Protein Kinase Inhibitors; Ribosomes; RNA, Messenger; T-Lymphocytes; Tryptophan

2021
Tryptophan: Its Metabolism along the Kynurenine, Serotonin, and Indole Pathway in Malignant Melanoma.
    International journal of molecular sciences, 2022, Aug-15, Volume: 23, Issue:16

    Topics: Humans; Indoles; Kynurenine; Melanoma; Melanoma, Cutaneous Malignant; Serotonin; Skin Neoplasms; Tryptophan

2022
Dietary tryptophan metabolite released by intratumoral Lactobacillus reuteri facilitates immune checkpoint inhibitor treatment.
    Cell, 2023, 04-27, Volume: 186, Issue:9

    Topics: CD8-Positive T-Lymphocytes; Diet; Humans; Immune Checkpoint Inhibitors; Limosilactobacillus reuteri; Melanoma; Receptors, Aryl Hydrocarbon; Tryptophan; Tumor Microenvironment

2023
The catalytic inhibitor epacadostat can affect the non-enzymatic function of IDO1.
    Frontiers in immunology, 2023, Volume: 14

    Topics: Humans; Kynurenine; Melanoma; Oximes; Tryptophan

2023
Increased tryptophan, but not increased glucose metabolism, predict resistance of pembrolizumab in stage III/IV melanoma.
    Oncoimmunology, 2023, Volume: 12, Issue:1

    Topics: Fluorodeoxyglucose F18; Glucose; Humans; Kynurenine; Melanoma; Melanoma, Cutaneous Malignant; Prospective Studies; Tryptophan

2023
Tryptophan metabolism-related gene expression patterns: unveiling prognostic insights and immune landscapes in uveal melanoma.
    Aging, 2023, 10-13, Volume: 15, Issue:20

    Topics: Gene Expression; Humans; Melanoma; Prognosis; Tryptophan; Tumor Microenvironment

2023
Effect of Indoleamine 2,3 Dioxygenase Inhibitor on the Cytotoxic Activity of Tumour-infiltrating Lymphocytes.
    Acta dermato-venereologica, 2019, Nov-01, Volume: 99, Issue:12

    Topics: Antineoplastic Agents; Cell Line, Tumor; Coculture Techniques; Enzyme Inhibitors; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Lymphocytes, Tumor-Infiltrating; Melanoma; Skin Neoplasms; Tryptophan

2019
Exhaustion of CD4+ T-cells mediated by the Kynurenine Pathway in Melanoma.
    Scientific reports, 2019, 08-21, Volume: 9, Issue:1

    Topics: B7-H1 Antigen; CD4-Positive T-Lymphocytes; Cell Line; Cell Proliferation; Coculture Techniques; Culture Media, Conditioned; Forkhead Transcription Factors; Gene Expression Regulation; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferon-gamma; Kynurenic Acid; Kynurenine; Melanoma; Melanoma, Cutaneous Malignant; Metabolic Networks and Pathways; Metabolomics; Proto-Oncogene Proteins B-raf; Skin Neoplasms; Tryptophan; Tumor Microenvironment; Up-Regulation

2019
Carbidopa Alters Tryptophan Metabolism in Breast Cancer and Melanoma Cells Leading to the Formation of Indole-3-Acetonitrile, a Pro-Proliferative Metabolite.
    Biomolecules, 2019, 08-24, Volume: 9, Issue:9

    Topics: Breast Neoplasms; Carbidopa; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chromatography, High Pressure Liquid; Female; Humans; Indoles; Melanoma; Skin Neoplasms; Spectrometry, Mass, Electrospray Ionization; Tryptophan

2019
Metabolomic adaptations and correlates of survival to immune checkpoint blockade.
    Nature communications, 2019, 09-25, Volume: 10, Issue:1

    Topics: Adaptation, Physiological; Aged; Antineoplastic Agents; Carcinoma, Renal Cell; Clinical Trials as Topic; Everolimus; Female; Humans; Kaplan-Meier Estimate; Kidney Neoplasms; Kynurenine; Male; Melanoma; Metabolomics; Middle Aged; Nivolumab; Programmed Cell Death 1 Receptor; Treatment Outcome; Tryptophan

2019
Assessment of clinical outcomes with immune checkpoint inhibitor therapy in melanoma patients with CDKN2A and TP53 pathogenic mutations.
    PloS one, 2020, Volume: 15, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antineoplastic Agents, Immunological; CTLA-4 Antigen; Cyclin-Dependent Kinase Inhibitor p16; Female; Humans; Immunotherapy; Ipilimumab; Male; Melanoma; Middle Aged; Mutation; Nivolumab; Programmed Cell Death 1 Receptor; Survival Analysis; Tryptophan; Tumor Suppressor Protein p53

2020
Comparing activity, toxicity and model membrane interactions of Jelleine-I and Trp/Arg analogs: analysis of peptide aggregation.
    Amino acids, 2020, Volume: 52, Issue:5

    Topics: Animals; Anti-Infective Agents; Antimicrobial Cationic Peptides; Antineoplastic Agents; Arginine; Candida; Cell Membrane; Hemolysis; Humans; Melanoma; Mice; Oligopeptides; Staphylococcus aureus; Streptococcus pneumoniae; Tryptophan

2020
Indoleamine 2,3-dioxygenase in melanoma progression and BRAF inhibitor resistance.
    Pharmacological research, 2020, Volume: 159

    Topics: Antineoplastic Agents; Cell Line, Tumor; Databases, Genetic; Drug Resistance, Neoplasm; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Melanoma; Molecular Targeted Therapy; Protein Kinase Inhibitors; Proto-Oncogene Proteins B-raf; Skin Neoplasms; Tryptophan; Vemurafenib

2020
Highly uniform self-assembled microspheres from single macromolecule self-recognition for enhanced cancer immunotherapy.
    Chemical communications (Cambridge, England), 2020, Aug-18, Volume: 56, Issue:64

    Topics: Animals; Antibodies; Antineoplastic Agents; Cell Line, Tumor; Drug Carriers; Drug Synergism; Enzyme Inhibitors; Female; Immunotherapy; Indoleamine-Pyrrole 2,3,-Dioxygenase; Melanoma; Mice, Inbred C57BL; Microspheres; Polyethylene Glycols; Programmed Cell Death 1 Receptor; Tryptophan

2020
The Endogenous Tryptophan-derived Photoproduct 6-formylindolo[3,2-b]carbazole (FICZ) is a Nanomolar Photosensitizer that Can be Harnessed for the Photodynamic Elimination of Skin Cancer Cells in Vitro and in Vivo.
    Photochemistry and photobiology, 2021, Volume: 97, Issue:1

    Topics: Animals; Carbazoles; Carcinoma, Squamous Cell; Cell Death; Cell Line, Tumor; Epidermis; Humans; Keratinocytes; Melanoma; Mice; Mitochondria; Oxidative Stress; Photochemotherapy; Photosensitizing Agents; Skin Neoplasms; Tryptophan; Ultraviolet Therapy

2021
Anti-tumour immunity induces aberrant peptide presentation in melanoma.
    Nature, 2021, Volume: 590, Issue:7845

    Topics: Antigen Presentation; Cell Line; Codon; Frameshift Mutation; Frameshifting, Ribosomal; Histocompatibility Antigens Class I; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferon-gamma; Melanoma; Peptides; Protein Biosynthesis; Proteome; Ribosomes; T-Lymphocytes; Tryptophan

2021
Bioinformatic Analysis Reveals Central Role for Tumor-Infiltrating Immune Cells in Uveal Melanoma Progression.
    Journal of immunology research, 2021, Volume: 2021

    Topics: Adult; Aged; Aged, 80 and over; Carcinogenesis; CD8-Positive T-Lymphocytes; Computational Biology; Data Mining; Disease Progression; Female; Humans; Lymphocytes, Tumor-Infiltrating; Male; Melanoma; Middle Aged; Neoplasm Metastasis; Tryptophan; Uveal Neoplasms; Young Adult

2021
Cold Atmospheric Plasma Changes the Amino Acid Composition of Solutions and Influences the Anti-Tumor Effect on Melanoma Cells.
    International journal of molecular sciences, 2021, Jul-23, Volume: 22, Issue:15

    Topics: Apoptosis; Cells, Cultured; Cyclin-Dependent Kinase Inhibitor p16; Humans; Melanocytes; Melanoma; Plasma Gases; Reactive Nitrogen Species; Reactive Oxygen Species; Tryptophan; Tyrosine

2021
The benefits of immunotherapy combinations.
    Nature, 2017, 12-21, Volume: 552, Issue:7685

    Topics: Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antigens, Neoplasm; Antineoplastic Agents, Immunological; Antineoplastic Combined Chemotherapy Protocols; B7-H1 Antigen; Biomarkers, Tumor; Cancer Vaccines; Cell Cycle Checkpoints; Clinical Trials as Topic; Combined Modality Therapy; CTLA-4 Antigen; Drug Costs; Humans; Immunotherapy; Indoleamine-Pyrrole 2,3,-Dioxygenase; Ipilimumab; Lung Neoplasms; Male; Melanoma; Nivolumab; Oncolytic Virotherapy; Patient Selection; Precision Medicine; Programmed Cell Death 1 Receptor; Survival Analysis; T-Lymphocytes; Tryptophan; Tumor Escape

2017
Critical residues in the PMEL/Pmel17 N-terminus direct the hierarchical assembly of melanosomal fibrils.
    Molecular biology of the cell, 2013, Volume: 24, Issue:7

    Topics: Amino Acid Sequence; Amyloid; Aspartic Acid; Binding Sites; Blotting, Western; Cell Line, Tumor; gp100 Melanoma Antigen; Humans; Melanins; Melanoma; Melanosomes; Microscopy, Electron, Transmission; Microscopy, Fluorescence; Molecular Sequence Data; Mutation; Organelles; Proline; Protein Transport; Proteolysis; Sequence Homology, Amino Acid; Tryptophan

2013
Screening of human primary melanocytes of defined melanocortin-1 receptor genotype: pigmentation marker, ultrastructural and UV-survival studies.
    Pigment cell research, 2003, Volume: 16, Issue:3

    Topics: Alleles; alpha-MSH; Antigens; Arginine; Cell Survival; Cells, Cultured; Cystine; Dihydroxyphenylalanine; DNA; Genetic Markers; Genotype; Heterozygote; Homozygote; Humans; Male; Melanins; Melanocytes; Melanoma; Melanosomes; Microscopy, Electron; Microscopy, Fluorescence; Monophenol Monooxygenase; Phenotype; Pigmentation; Tryptophan; Ultraviolet Rays

2003
Plasma homocysteine and immune activation in patients with malignant melanoma undergoing treatment with IFN-alpha.
    Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research, 2004, Volume: 24, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents; Female; Folic Acid; Homocysteine; Humans; Interferon alpha-2; Interferon-alpha; Kynurenine; Macrophage Activation; Male; Melanoma; Middle Aged; Neopterin; Predictive Value of Tests; Recombinant Proteins; Tryptophan; Vitamin B 12

2004
Differential effects of the tryptophan metabolite 3-hydroxyanthranilic acid on the proliferation of human CD8+ T cells induced by TCR triggering or homeostatic cytokines.
    European journal of immunology, 2006, Volume: 36, Issue:2

    Topics: 3-Hydroxyanthranilic Acid; Antigen Presentation; CD8-Positive T-Lymphocytes; Cell Line, Tumor; Cell Proliferation; Cytokines; Dendritic Cells; Free Radical Scavengers; Homeostasis; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Melanoma; Neoplasm Proteins; Receptors, Antigen, T-Cell; Tryptophan

2006
Decreased serum tryptophan concentration predicts poor prognosis in malignant melanoma patients.
    Dermatology (Basel, Switzerland), 2007, Volume: 214, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Chromatography, High Pressure Liquid; Disease Progression; Female; Follow-Up Studies; Humans; Male; Melanoma; Middle Aged; Neoplasm Staging; Neopterin; Prognosis; Retrospective Studies; Skin Neoplasms; Survival Rate; Tryptophan

2007
Dendritic cell based antitumor vaccination: impact of functional indoleamine 2,3-dioxygenase expression.
    Cancer immunology, immunotherapy : CII, 2007, Volume: 56, Issue:7

    Topics: Adult; Animals; Blotting, Western; Cancer Vaccines; Dendritic Cells; Female; Forkhead Transcription Factors; Humans; Immunohistochemistry; Immunotherapy; Indoleamine-Pyrrole 2,3,-Dioxygenase; Lymphocytes, Tumor-Infiltrating; Male; Melanoma; Middle Aged; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tryptophan

2007
Uveal melanoma expression of indoleamine 2,3-deoxygenase: establishment of an immune privileged environment by tryptophan depletion.
    Experimental eye research, 2007, Volume: 85, Issue:5

    Topics: Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Humans; Immune Tolerance; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferon-gamma; Liver Neoplasms; Melanoma; Metabolism; Recombinant Proteins; Reverse Transcriptase Polymerase Chain Reaction; Transcription, Genetic; Tryptophan; Tumor Cells, Cultured; Up-Regulation; Uveal Neoplasms

2007
Aminoacids--precursors of melanin synthesis in hamster melanoma.
    Journal of cancer research and clinical oncology, 1984, Volume: 108, Issue:3

    Topics: Amino Acids; Animals; Cricetinae; Ferrous Compounds; Iron; Levodopa; Male; Melanins; Melanoma; Mesocricetus; Neoplasm Transplantation; Phenylalanine; Tryptophan; Tyrosine

1984
Enzyme activities and metabolites along the kynurenine pathway in mice with Harding-Passey melanoma.
    Acta vitaminologica et enzymologica, 1983, Volume: 5, Issue:2

    Topics: Animals; Hydrolases; Kynurenine; Lyases; Melanoma; Mice; Neoplasm Transplantation; Transaminases; Tryptophan; Tryptophan Oxygenase

1983
Occurrence of indoleamine 2,3-dioxygenase in human cutaneous malignant melanoma.
    Advances in experimental medicine and biology, 1996, Volume: 398

    Topics: Humans; Lymph Nodes; Melanoma; Skin; Skin Neoplasms; Tryptophan; Tryptophan Oxygenase

1996
Effects of melatonin, its precursors and derivatives on the growth of cultured human uveal melanoma cells.
    Melanoma research, 1998, Volume: 8, Issue:3

    Topics: Cell Division; Dose-Response Relationship, Drug; Humans; Kynurenine; Melanoma; Melatonin; Serotonin; Tryptophan; Tumor Cells, Cultured; Uveal Neoplasms

1998
Genotype-phenotype relationships in U.S. melanoma-prone families with CDKN2A and CDK4 mutations.
    Journal of the National Cancer Institute, 2000, Jun-21, Volume: 92, Issue:12

    Topics: Adolescent; Adult; Age Factors; Aged; Arginine; Aspartic Acid; Cyclin-Dependent Kinases; Cysteine; Genes, p16; Genotype; Germ-Line Mutation; Glycine; Haplotypes; Humans; Melanoma; Middle Aged; Nevus; Pancreatic Neoplasms; Phenotype; Skin Neoplasms; Statistics, Nonparametric; Tryptophan; United States; Valine

2000
Disruption of protein phosphatase 2A subunit interaction in human cancers with mutations in the A alpha subunit gene.
    Oncogene, 2001, Jan-04, Volume: 20, Issue:1

    Topics: Amino Acid Sequence; Arginine; Aspartic Acid; Breast Neoplasms; Female; Glutamic Acid; Glycine; Humans; Lung Neoplasms; Melanoma; Molecular Sequence Data; Neoplasms; Peptide Fragments; Phosphoprotein Phosphatases; Point Mutation; Protein Binding; Protein Phosphatase 2; Protein Structure, Secondary; Tryptophan

2001
Conversion of L-tryptophan to serotonin and melatonin in human melanoma cells.
    FEBS letters, 2002, Jan-30, Volume: 511, Issue:1-3

    Topics: Acetylserotonin O-Methyltransferase; Chromatography, High Pressure Liquid; Humans; Melanoma; Melatonin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Serotonin; Spectrometry, Mass, Electrospray Ionization; Tryptophan; Tryptophan Hydroxylase; Tumor Cells, Cultured

2002
Acceptability and tolerance of a low tyrosine and phenylalanine diet in patients with advanced cancer -- a pilot study.
    Journal of human nutrition and dietetics : the official journal of the British Dietetic Association, 2002, Volume: 15, Issue:3

    Topics: Adult; Aged; Breast Neoplasms; Depression; Female; Humans; Male; Melanoma; Middle Aged; Neoplasm Metastasis; Nutritional Status; Phenylalanine; Pilot Projects; Quality of Life; Treatment Outcome; Tryptophan; Tyrosine

2002
Studies on melanogenesis of tryptophan in Harding-Passey mouse melanoma.
    Acta vitaminologica et enzymologica, 1975, Volume: 29, Issue:1-6

    Topics: Animals; Melanins; Melanoma; Mice; Neoplasms, Experimental; Pigments, Biological; Tryptophan

1975
Vitamin B6 deficiency and carcinogenesis.
    Advances in experimental medicine and biology, 1986, Volume: 206

    Topics: Animals; Humans; Melanoma; Neoplasms; Neoplasms, Experimental; Pyridoxine; Tryptophan; Vitamin B 6 Deficiency

1986
Inhibition of gluconeogenesis at the phosphoenolpyruvate carboxykinase and pyruvate carboxylase reactions, as a means of cancer chemotherapy.
    Oncology, 1974, Volume: 29, Issue:1

    Topics: Animals; Carcinoma 256, Walker; Female; Gluconeogenesis; HeLa Cells; Hydrazines; Liver; Lymphoma, Non-Hodgkin; Male; Melanoma; Mice; Neoplasms, Experimental; Phosphoenolpyruvate Carboxykinase (GTP); Pyruvate Carboxylase; Rats; Tryptophan

1974
[Malignant melanoma and L-dopa. Review of literature on the problem of causal relationship].
    Fortschritte der Medizin, 1974, Sep-26, Volume: 92, Issue:27

    Topics: Humans; Levodopa; Male; Melanins; Melanoma; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Parkinson Disease; Skin Neoplasms; Tryptophan

1974
An abnormal orosomucoid in the plasma of patients with neoplastic disease.
    Cancer research, 1972, Volume: 32, Issue:9

    Topics: Adult; Amino Acids; Carcinoma, Bronchogenic; Chromatography, Gel; Chromatography, Ion Exchange; Colonic Neoplasms; Female; Glucosamine; Glycoproteins; Hexoses; Humans; Immunodiffusion; Immunoelectrophoresis; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Melanoma; Middle Aged; Neoplasm Metastasis; Neoplasms; Neuraminic Acids; Ovarian Neoplasms; Tryptophan

1972
Melanogenesis from tryptophan. Biogenetic experiments with Harding-Passey mouse melanoma.
    Experientia, 1974, Jun-15, Volume: 30, Issue:6

    Topics: Animals; Carbon Radioisotopes; Kynurenine; Melanins; Melanoma; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Tryptophan; Tyrosine

1974