tryptophan and Lung Neoplasms

tryptophan has been researched along with Lung Neoplasms in 59 studies

Research

Studies (59)

Timeframe	Studies, this research(%)	All Research%
pre-1990	6 (10.17)	18.7374
1990's	2 (3.39)	18.2507
2000's	9 (15.25)	29.6817
2010's	20 (33.90)	24.3611
2020's	22 (37.29)	2.80

Authors

Authors	Studies
Chen, J; Dong, B; Dong, Y; Guo, G; Hou, Z; Jiang, H; Li, H; Li, J; Li, X; Sun, Z; Wang, Y; Xue, X; Yang, JH; Yang, Y; Zhang, A; Zhang, G; Zhang, L; Zhu, Q	1
Azuma, K; Hoshino, T; Imaizumi, A; Ishii, H; Karakawa, S; Kasajima, R; Kato, Y; Kawahara, A; Kikuchi, S; Matsuo, N; Miyagi, Y; Murotani, K; Sasada, T; Tagami, T; Tokito, T; Xiang, H	1
Cao, B; Feng, H; Peng, X; Wei, Q	1
Abd El-Fattah, EE	1
Bi, N; Chen, Y; Qian, M; Wang, D; Wang, L; Wu, L; Xu, X; Zhang, T	1
DI, LQ; Huang, X; Lu, YY; Luo, ZC; Qi, MY; Shan, JJ; Zhang, W	1
Arslan, AA; Behndig, AF; Brennan, P; Cai, Q; Chen, C; Chen, Y; Fanidi, A; Freedman, ND; Gaziano, JM; Giles, GG; Huang, WY; Johansson, M; Koh, WP; Langhammer, A; Le Marchand, L; Manjer, J; Meyer, K; Midttun, Ø; Prentice, R; Robbins, HA; Sandsveden, M; Sesso, HD; Shu, XO; Stevens, VL; Sørgjerd, EP; Ueland, PM; Ulvik, A; Visvanathan, K; Wang, Y; Weinstein, SJ; Yuan, JM; Zahed, H; Zhang, X; Zheng, W	1
Chen, L; Du, H; Guan, J; Hu, Y; Huang, P; Huo, B; Liu, Q; Liu, W; Liu, Y; Lu, W; Luan, T; Luo, Y; Wang, X; Xie, C; Yang, J; Yao, Y; Yu, T; Zhang, H; Zhao, M	1
Cai, H; Guo, Y; Jiang, H; Juhasz, C; Muzik, O; Shields, AF; Viola, N	1
Bai, Y; Chen, F; Ma, J; Wang, D; Xue, P; Zhang, L; Zhou, F	1
Cao, B; Fei, F; Jiang, J; Jin, D; Li, J; Sun, R; Wang, M; Xu, Z; Yang, G; Yang, N	1
Bessede, A; Cabart, M; Chomy, F; Cousin, S; Guegan, JP; Italiano, A; Lara, O; Le Moulec, S; Nafia, I; Odin, O; Peyraud, F; Rey, C	1
Bader, B; Batra, AS; Baumann, D; Carretero, R; Cichon, F; Elmadany, N; Gorjánácz, M; Gutcher, I; Hartung, IV; Irlbacher, H; Kober, C; Kreft, B; Leder, G; Lefranc, J; Lesche, R; Oezcan-Wahlbrink, M; Oezen, I; Offringa, R; Olesch, C; Opitz, CA; Platten, M; Prinz, F; Roehn, U; Roese, L; Roewe, J; Roider, HG; Sadik, A; Sahm, K; Schmees, N; Stoeckigt, D; Weinmann, H	1
Conacci-Sorrell, M; DeBerardinis, RJ; Gao, B; Mendelson, CR; Minna, JD; Nawas, AF; Solmonson, A	1
Ambrosino, S; Belladonna, ML; De Marchis, F; Gargaro, M; Mandarano, M; Mondanelli, G; Orabona, C; Pallotta, MT; Panfili, E; Rossini, S; Suvieri, C; Volpi, C	1
Chang, YJ; Kuo, YT; Liang, PH; Liu, YJ	1
Enomoto, N; Fujisawa, T; Furuhashi, K; Hozumi, H; Inui, N; Karayama, M; Maekawa, M; Masuda, J; Mori, K; Nakamura, Y; Suda, T; Sugimura, H; Suzuki, Y; Takada, A; Yasui, H	1
Bui, MM; Gong, L; Sun, X; Yi, D; Zhang, M; Zhang, W	1
An, C; Cho, SY; Chung, H; Jang, M; Jeon, BN; Jeong, JJ; Kim, G; Kim, H; Kim, HS; Kim, S; Kim, SG; Kim, Y; Kim, YY; Kwon, JY; Lee, C; Lee, EJ; Lee, GB; Lee, S; Lee, SH; Moon, MH; Nam, MH; Park, C; Park, H; Park, JS; Sohn, J; Weinstock, GM; Won, S; Yang, HS; Yoon, KW; Yoon, Y	1
Baglivo, S; Belladonna, ML; Bellezza, G; Chiari, R; Loreti, E; Ludovini, V; Mandarano, M; Orecchini, E; Puma, F; Sidoni, A; Tofanetti, FR; Vannucci, J	1
Cai, J; Cao, Y; Fan, X; Fu, Y; Hsiao, WW; Huang, J; Jiang, Z; Khan, I; Lai, H; Leung, EL; Li, J; Li, R; Liao, J; Liu, D; Liu, H; Liu, L; Liu, Z; Lu, J; Luo, L; Shi, A; Wang, L; Wang, W; Wang, Y; Wei, H; Wu, J; Wu, Q; Xie, Y; Yan, P; Yang, M; Yao, X; Yuan, J; Zhang, Y	1
Aojula, HS; Freeman, S; Haitham Abusara, O	1
Huang, L; Jin, JY; Jolly, S; Kong, FS; Li, L; Mellor, AL; Pi, W; Wang, W; Wu, H; Yan, L; Zang, Y	1
Schmidt, C	1
Abu Eid, R; Ahmad, S; Berrong, Z; Hammond, S; Janik, JE; Khleif, SN; Matevosyan, A; Mkrtichyan, M; Mohamed, E; Okoev, G; Shrimali, R; Webb, M	1
Barsoumian, HB; Caetano, MS; Cortez, MA; Cushman, TR; Li, A; Li, G; Niknam, S; Schoenhals, JE; Valdecanas, DR; Wang, X; Welsh, JW; Woodward, WA; Younes, AI	1
Chang, TC; Chen, HL; Cheng, HH; Huang, SK; Kuo, CC; Wu, KK; Yuan, CY	1
Botticelli, A; Cerbelli, B; Federica, M; Lionetto, L; Marchetti, P; Nuti, M; Pisano, A; Salati, M; Simmaco, M; Zizzari, I	1
Albanes, D; Alcala, K; Arslan, AA; Blot, WJ; Brennan, P; Buring, JE; Cai, Q; Caporaso, NE; Fanidi, A; Freedman, ND; Gao, YT; Gaziano, JM; Giles, GG; Grankvist, K; Haiman, CA; Han, J; Hodge, AM; Huang, JY; Hveem, K; Johansson, M; Koh, WP; Lan, Q; Langhammer, A; Larose, TL; Le Marchand, L; Lee, IM; Li, HL; Luu, HN; Manjer, J; Midttun, Ø; Pettinger, M; Prentice, RL; Purdue, MP; Relton, C; Sesso, HD; Severi, G; Shu, XO; Stampfer, MJ; Stevens, VL; Thomson, CA; Ueland, PM; Ulvi, A; Visvanathan, K; Wang, R; Weinstein, SJ; Wilkens, LR; Wu, J; Xiang, YB; Yuan, JM; Zeleniuch-Jacquotte, A; Zhang, X; Zheng, W; Ziegler, RG	1
Andersen, MH; Andersen, R; Bjoern, J; Ellebaek, E; Engell-Noerregaard, L; Gouttefangeas, C; Holm, B; Iversen, TZ; Larsen, SK; Mellemgaard, A; Svane, IM; Thomsen, BM; Thor Straten, P; Zeyher, C	1
Ametamey, SM; Chiotellis, A; Keller, C; Krämer, SD; Mu, L; Müller, A; Schibli, R; Selivanova, SV	1
Agnoli, C; Agudo, A; Aicua, EA; Boeing, H; Boutron-Ruault, MC; Brennan, PJ; Bueno-de-Mesquita, HB; Chirlaque, MD; Chuang, SC; Clavel-Chapelon, F; Fagherazzi, G; Fanidi, A; Grankvist, K; Gunter, MJ; Johansson, M; Kaaks, R; Kuehn, T; Lagiou, P; Midttun, O; Naccarati, A; Palli, D; Peeters, PH; Quirós, JR; Relton, C; Riboli, E; Sánchez, MJ; Seckl, MJ; Travis, RC; Trichopoulos, D; Trichopoulou, A; Tumino, R; Ueland, PM; Vineis, P; Vollset, SE; Wareham, N; Weiderpass, E; Wientzek, A	1
Ametamey, SM; Chiotellis, A; Keller, C; Krämer, SD; Mu, L; Muller, A; Schibli, R	1
Levine, A; Sun, Y; Yi, L	1
Chen, HL; Cheng, HH; Chiang, LY; Chu, LY; Kuo, CC; Wu, KK	1
Armutlulu, A; Balaram, H; Balasubramanian, S; Bartosh, TJ; Broda, M; Brown, LE; Burroughs, LM; Burrows, F; Cardoso, JR; Carregaro, RL; Cho, J; Cui, Q; Dela Bela, LF; Dias, JM; Dutta, NK; Flowers, ME; Gallo, S; Hari, P; He, R; He, Y; Heimfeld, S; Jia, B; Jin, X; Jin, YJ; Karakousis, PC; Karmakar, T; Kiem, HP; Kreager, DA; Lebedev, D; Li, F; Li, S; Liang, N; Liu, Z; Luo, J; Luo, Y; Mazuquin, BF; Meng, Y; Mosialos, G; Moura, FA; Müller, CR; Naeem, MA; Nagappa, LK; Nguyen, H; Pelegrinelli, AR; Pinn, ML; Prahlada Rao, VS; Pulsipher, MA; Ragan, DT; Richards, J; Roy, S; Sandmaier, BM; Selfe, J; Selim, MA; Shi, J; Shi, X; Staff, J; Storb, R; Storer, BE; Wang, F; Wang, M; Wang, S; Woolfrey, AE; Wright, T; Ylostalo, JH; Zhang, JY; Zhang, ZY; Zheng, K; Zhu, Z	1
Cheng, X; Hao, H; Li, Q; Liu, F; Liu, H; Wang, G; Wang, H; Xing, R; Ye, H; Zhao, M	1
Chakraborty, PK; Chugani, DC; Jahania, MS; Juhász, C; Khalaf, M; Lu, X; Mangner, TJ; Muzik, O; Peng, F; Soubani, AO	1
Chida, K; Fujie, M; Furuhashi, K; Hahimoto, D; Inui, N; Nakamura, H; Nakamura, Y; Suda, T; Suzuki, M; Suzuki, Y	1
Drozdov, I; Gustafsson, BI; Joseph, R; Kidd, M; Modlin, IM; Pfragner, R; Svejda, B	1
Hu, B; Hu, S; Shen, G; Xu, W; Yin, S	1
Ren, YP; Tang, AG; Xiang, ZY; Zhou, QX	1
Li, J; Li, L; Qiang, M; Sun, S; Tang, B; Xu, K	1
Denz, HA; Fiegl, M; Fuchs, D; Giesinger, J; Holzner, B; Kurz, K; Pircher, M; Weiss, G	1
Carranza, A; Coveñas, R; González-Ortega, A; Muñoz, M; Robles-Frias, MJ; Rosso, M; Salinas-Martín, MV	1
Bader, M; Peter, JU; Walther, DJ	1
Bencko, V; Boffetta, P; Borel, S; Brennan, P; Canzian, F; Chabrier, A; Fabianova, E; Foretova, L; Hall, J; Hung, RJ; Janout, V; Lissowska, J; Mates, D; Rudnai, P; Szeszenia-Dabrowska, N; Zaridze, D	1
Hu, B; Hu, SL; Shen, G; Wang, H; Wang, WD; Xu, WP; Yin, S; Zhang, Q	1
Kaur, P; Pachouri, SS; Singh, J; Sobti, RC	1
de Villiers, EM; Fei, JW	1
Blanck, G; Eason, DD; Shepherd, AT	1
Pham, HT; Ruediger, R; Walter, G	1
Cangiano, C; Cascino, A; Ceci, F; Laviano, A; Mulieri, M; Muscaritoli, M; Rossi-Fanelli, F	1
Hayaishi, O; Takai, K; Yasui, H; Yoshida, R	1
Leodolter, I; Petzelbauer, L; Sieberth, E	1
Dzhioev, FK	1
Ehrhart, H	1
Brown, RR; DeGeorge, FV	1
Grover, V; Kazi, MU	1

Reviews

1 review(s) available for tryptophan and Lung Neoplasms

Article	Year
IDO/kynurenine pathway in cancer: possible therapeutic approaches. Journal of translational medicine, 2022, 08-02, Volume: 20, Issue:1 Topics: Female; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Lung Neoplasms; Male; Tryptophan; Tumor Microenvironment	2022

Trials

2 trial(s) available for tryptophan and Lung Neoplasms

Article	Year
Long-lasting disease stabilization in the absence of toxicity in metastatic lung cancer patients vaccinated with an epitope derived from indoleamine 2,3 dioxygenase. Clinical cancer research : an official journal of the American Association for Cancer Research, 2014, Jan-01, Volume: 20, Issue:1 Topics: Adenocarcinoma; Adjuvants, Immunologic; Aged; Cancer Vaccines; Carcinoma, Non-Small-Cell Lung; Disease-Free Survival; Female; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kaplan-Meier Estimate; Kynurenine; Lung Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Statistics, Nonparametric; T-Lymphocytes, Regulatory; Treatment Outcome; Tryptophan; Vaccination	2014
[The effect of amino acid nutritional support on serum tryptophan and melatonin in lung cancer patients receiving chemotherapy]. Zhonghua zhong liu za zhi [Chinese journal of oncology], 2006, Volume: 28, Issue:11 Topics: Aged; Amino Acids; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Cisplatin; Female; Humans; Lung Neoplasms; Male; Melatonin; Neoplasm Staging; Parenteral Nutrition; Treatment Outcome; Tryptophan; Vinblastine; Vinorelbine	2006

Article

Year

Long-lasting disease stabilization in the absence of toxicity in metastatic lung cancer patients vaccinated with an epitope derived from indoleamine 2,3 dioxygenase.

Clinical cancer research : an official journal of the American Association for Cancer Research, 2014, Jan-01, Volume: 20, Issue:1

Topics: Adenocarcinoma; Adjuvants, Immunologic; Aged; Cancer Vaccines; Carcinoma, Non-Small-Cell Lung; Disease-Free Survival; Female; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kaplan-Meier Estimate; Kynurenine; Lung Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Statistics, Nonparametric; T-Lymphocytes, Regulatory; Treatment Outcome; Tryptophan; Vaccination

2014

[The effect of amino acid nutritional support on serum tryptophan and melatonin in lung cancer patients receiving chemotherapy].

Zhonghua zhong liu za zhi [Chinese journal of oncology], 2006, Volume: 28, Issue:11

Topics: Aged; Amino Acids; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Cisplatin; Female; Humans; Lung Neoplasms; Male; Melatonin; Neoplasm Staging; Parenteral Nutrition; Treatment Outcome; Tryptophan; Vinblastine; Vinorelbine

2006

Other Studies

56 other study(ies) available for tryptophan and Lung Neoplasms

Article	Year
Open Search-Based Proteomics Reveals Widespread Tryptophan Modifications Associated with Hypoxia in Lung Cancer. Oxidative medicine and cellular longevity, 2022, Volume: 2022 Topics: Carcinoma, Non-Small-Cell Lung; Humans; Hypoxia; Lung Neoplasms; Proteome; Proteomics; Tryptophan	2022
Clinical significance of plasma-free amino acids and tryptophan metabolites in patients with non-small cell lung cancer receiving PD-1 inhibitor: a pilot cohort study for developing a prognostic multivariate model. Journal for immunotherapy of cancer, 2022, Volume: 10, Issue:5 Topics: Amino Acids; Arginine; Carcinoma, Non-Small-Cell Lung; Glycine; Humans; Immune Checkpoint Inhibitors; Leukocytes, Mononuclear; Lung Neoplasms; Neopterin; Pilot Projects; Prognosis; Quinolinic Acids; Tryptophan	2022
Cancer-associated fibroblasts strengthen cell proliferation and EGFR TKIs resistance through aryl hydrocarbon receptor dependent signals in non-small cell lung cancer. BMC cancer, 2022, Jul-13, Volume: 22, Issue:1 Topics: Cancer-Associated Fibroblasts; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; ErbB Receptors; Humans; Lung Neoplasms; Protein Kinase Inhibitors; Receptors, Aryl Hydrocarbon; Tryptophan; Tumor Microenvironment	2022
Dynamic change of IDO1 activity predicts survival in patients with unresectable stage III NSCLC and chemoradiotherapy. Frontiers in immunology, 2022, Volume: 13 Topics: Carcinoma, Non-Small-Cell Lung; Chemoradiotherapy; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Lung Neoplasms; Tryptophan	2022
[Mechanism of Cordyceps militaris against non-small cell lung cancer: based on serum metabolomics]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 2022, Volume: 47, Issue:18 Topics: Alanine; Animals; Arginine; Aspartic Acid; Carcinoma, Non-Small-Cell Lung; Cisplatin; Cordyceps; Glutamic Acid; Glutamine; Glyoxylates; Humans; Lung Neoplasms; Metabolomics; Mice; Mice, Nude; Nitrogen; Phenylalanine; RNA, Transfer; Tryptophan; Tyrosine	2022
A cross-sectional study of inflammatory markers as determinants of circulating kynurenines in the Lung Cancer Cohort Consortium. Scientific reports, 2023, 01-18, Volume: 13, Issue:1 Topics: Biomarkers; C-Reactive Protein; Cross-Sectional Studies; Humans; Inflammation; Interferon-gamma; Kynurenine; Lung Neoplasms; NAD; Neopterin; Tryptophan	2023
Metabolomic differentiation of benign vs malignant pulmonary nodules with high specificity via high-resolution mass spectrometry analysis of patient sera. Nature communications, 2023, 04-24, Volume: 14, Issue:1 Topics: Adenocarcinoma of Lung; Cell Differentiation; Diagnosis, Differential; Humans; Lung Neoplasms; Multiple Pulmonary Nodules; Tryptophan	2023
Automated radiosynthesis of 1-(2-[ Journal of labelled compounds & radiopharmaceuticals, 2023, Volume: 66, Issue:7-8 Topics: Fluorine Radioisotopes; Humans; Lung Neoplasms; Male; Positron-Emission Tomography; Prostatic Neoplasms; Radiopharmaceuticals; Tryptophan	2023
MicroRNA-185-5p targets tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta to regulate non-small cell lung cancer progression. Journal of cardiothoracic surgery, 2023, Jul-31, Volume: 18, Issue:1 Topics: Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Humans; Luciferases; Lung Neoplasms; MicroRNAs; Tryptophan; Tyrosine 3-Monooxygenase	2023
Integration of metabolomics and machine learning revealed tryptophan metabolites are sensitive biomarkers of pemetrexed efficacy in non-small cell lung cancer. Cancer medicine, 2023, Volume: 12, Issue:18 Topics: Biomarkers; Carcinoma, Non-Small-Cell Lung; Chromatography, Liquid; Humans; Lung Neoplasms; Pemetrexed; Pyruvates; Tandem Mass Spectrometry; Tryptophan	2023
Upregulation of Indoleamine 2,3-Dioxygenase 1 in Tumor Cells and Tertiary Lymphoid Structures is a Hallmark of Inflamed Non-Small Cell Lung Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research, 2023, Dec-01, Volume: 29, Issue:23 Topics: B7-H1 Antigen; Carcinoma, Non-Small-Cell Lung; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Lung Neoplasms; Tertiary Lymphoid Structures; Tryptophan; Up-Regulation	2023
Targeting the aryl hydrocarbon receptor (AhR) with BAY 2416964: a selective small molecule inhibitor for cancer immunotherapy. Journal for immunotherapy of cancer, 2023, Volume: 11, Issue:11 Topics: Animals; Carcinoma, Non-Small-Cell Lung; Dioxygenases; Head and Neck Neoplasms; Humans; Immunologic Factors; Immunotherapy; Kynurenine; Leukocytes, Mononuclear; Lung Neoplasms; Mice; Receptors, Aryl Hydrocarbon; Squamous Cell Carcinoma of Head and Neck; Tryptophan; Tumor Microenvironment	2023
IL-1β mediates the induction of immune checkpoint regulators IDO1 and PD-L1 in lung adenocarcinoma cells. Cell communication and signaling : CCS, 2023, Nov-20, Volume: 21, Issue:1 Topics: Adenocarcinoma of Lung; B7-H1 Antigen; Humans; Kynurenine; Lung Neoplasms; RNA, Messenger; Tryptophan; Tumor Microenvironment	2023
Membrane Localization and Phosphorylation of Indoleamine 2,3-Dioxygenase 2 (IDO2) in A549 Human Lung Adenocarcinoma Cells: First Steps in Exploring Its Signaling Function. International journal of molecular sciences, 2023, Nov-12, Volume: 24, Issue:22 Topics: Adenocarcinoma of Lung; Carcinoma, Non-Small-Cell Lung; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Lung Neoplasms; Phosphorylation; Tryptophan	2023
Targeting β-tubulin/CCT-β complex induces apoptosis and suppresses migration and invasion of highly metastatic lung adenocarcinoma. Carcinogenesis, 2020, 07-10, Volume: 41, Issue:5 Topics: Adenocarcinoma of Lung; Apoptosis; Cell Movement; Cell Proliferation; Chaperonin Containing TCP-1; Epithelial-Mesenchymal Transition; Humans; Lung Neoplasms; Neoplasm Invasiveness; Tryptophan; Tubulin; Tumor Cells, Cultured	2020
Comprehensive assessment of multiple tryptophan metabolites as potential biomarkers for immune checkpoint inhibitors in patients with non-small cell lung cancer. Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2021, Volume: 23, Issue:2 Topics: 3-Hydroxyanthranilic Acid; Adult; Aged; Aged, 80 and over; B7-H1 Antigen; Biomarkers; Carcinoma, Non-Small-Cell Lung; Female; Humans; Immune Checkpoint Inhibitors; Lung Neoplasms; Male; Middle Aged; Progression-Free Survival; Prospective Studies; Regression Analysis; ROC Curve; Sensitivity and Specificity; Treatment Outcome; Tryptophan; Xanthurenates	2021
H3F3A G34 mutation DNA sequencing and G34W immunohistochemistry analysis in 366 cases of giant cell tumors of bone and other bone tumors. Histology and histopathology, 2021, Volume: 36, Issue:1 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Bone Neoplasms; Child; Child, Preschool; Diagnosis, Differential; Female; Giant Cell Tumor of Bone; Glycine; Histones; Humans; Immunohistochemistry; Lung Neoplasms; Male; Middle Aged; Mutation; Sequence Analysis, DNA; Tryptophan; Young Adult	2021
Bifidobacterium bifidum strains synergize with immune checkpoint inhibitors to reduce tumour burden in mice. Nature microbiology, 2021, Volume: 6, Issue:3 Topics: Animals; Bifidobacterium bifidum; Carcinoma, Non-Small-Cell Lung; Drug Therapy, Combination; Gastrointestinal Microbiome; Humans; Immune Checkpoint Inhibitors; Interferon-gamma; Lung Neoplasms; Metabolome; Mice; Neoplasms, Experimental; Probiotics; Species Specificity; Transcriptome; Tryptophan; Tumor Burden	2021
Kynurenine/Tryptophan Ratio as a Potential Blood-Based Biomarker in Non-Small Cell Lung Cancer. International journal of molecular sciences, 2021, Apr-22, Volume: 22, Issue:9 Topics: Adenocarcinoma of Lung; Adult; Aged; Aged, 80 and over; B7-H1 Antigen; Biomarkers, Tumor; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Female; Follow-Up Studies; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Lung Neoplasms; Lymphocytes, Tumor-Infiltrating; Male; Middle Aged; Neoplasm Recurrence, Local; Prognosis; Survival Rate; Tryptophan	2021
Ginseng polysaccharides alter the gut microbiota and kynurenine/tryptophan ratio, potentiating the antitumour effect of antiprogrammed cell death 1/programmed cell death ligand 1 (anti-PD-1/PD-L1) immunotherapy. Gut, 2022, Volume: 71, Issue:4 Topics: Animals; Antibodies, Monoclonal; Apoptosis; B7-H1 Antigen; Carcinoma, Non-Small-Cell Lung; Cell Death; Gastrointestinal Microbiome; Humans; Immunologic Factors; Immunotherapy; Kynurenine; Ligands; Lung Neoplasms; Mice; Panax; Polysaccharides; Tryptophan	2022
Pentapeptides for the treatment of small cell lung cancer: Optimisation by N European journal of medicinal chemistry, 2017, Sep-08, Volume: 137 Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Lung Neoplasms; Molecular Structure; Oligopeptides; Small Cell Lung Carcinoma; Structure-Activity Relationship; Tryptophan	2017
IDO Immune Status after Chemoradiation May Predict Survival in Lung Cancer Patients. Cancer research, 2018, 02-01, Volume: 78, Issue:3 Topics: Adenocarcinoma; Aged; Biomarkers, Tumor; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Chemoradiotherapy; Disease Progression; Female; Follow-Up Studies; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Lung Neoplasms; Male; Prognosis; Prospective Studies; Survival Rate; Tryptophan	2018
The benefits of immunotherapy combinations. Nature, 2017, 12-21, Volume: 552, Issue:7685 Topics: Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antigens, Neoplasm; Antineoplastic Agents, Immunological; Antineoplastic Combined Chemotherapy Protocols; B7-H1 Antigen; Biomarkers, Tumor; Cancer Vaccines; Cell Cycle Checkpoints; Clinical Trials as Topic; Combined Modality Therapy; CTLA-4 Antigen; Drug Costs; Humans; Immunotherapy; Indoleamine-Pyrrole 2,3,-Dioxygenase; Ipilimumab; Lung Neoplasms; Male; Melanoma; Nivolumab; Oncolytic Virotherapy; Patient Selection; Precision Medicine; Programmed Cell Death 1 Receptor; Survival Analysis; T-Lymphocytes; Tryptophan; Tumor Escape	2017
Antigen-Specific Antitumor Responses Induced by OX40 Agonist Are Enhanced by the IDO Inhibitor Indoximod. Cancer immunology research, 2018, Volume: 6, Issue:2 Topics: Animals; Antigens, Differentiation; Cancer Vaccines; Epitopes, T-Lymphocyte; Female; Humans; Immunotherapy; Lung Neoplasms; Mice; Mice, Inbred C57BL; Tryptophan; Tryptophan Oxygenase; Xenograft Model Antitumor Assays	2018
Indoleamine 2,3-dioxygenase 1 inhibition targets anti-PD1-resistant lung tumors by blocking myeloid-derived suppressor cells. Cancer letters, 2018, 09-01, Volume: 431 Topics: Animals; Cell Line, Tumor; Enzyme Inhibitors; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Immunosuppression Therapy; Immunosuppressive Agents; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Lung Neoplasms; Mice; Myeloid-Derived Suppressor Cells; Neoplasm Transplantation; Tryptophan; Tumor Microenvironment	2018
Restoration of hydroxyindole The Journal of biological chemistry, 2018, 07-13, Volume: 293, Issue:28 Topics: Acetylserotonin O-Methyltransferase; Animals; Apoptosis; Cell Proliferation; Humans; Lung Neoplasms; Male; Mice; Mice, SCID; Serotonin; Tryptophan; Tumor Cells, Cultured; Xenograft Model Antitumor Assays	2018
Can IDO activity predict primary resistance to anti-PD-1 treatment in NSCLC? Journal of translational medicine, 2018, 08-06, Volume: 16, Issue:1 Topics: Aged; Carcinoma, Non-Small-Cell Lung; Disease Progression; Drug Resistance, Neoplasm; Female; Humans; Immunotherapy; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kaplan-Meier Estimate; Kynurenine; Lung Neoplasms; Male; Multivariate Analysis; Programmed Cell Death 1 Receptor; Quinolinic Acid; Tryptophan	2018
Circulating markers of cellular immune activation in prediagnostic blood sample and lung cancer risk in the Lung Cancer Cohort Consortium (LC3). International journal of cancer, 2020, 05-01, Volume: 146, Issue:9 Topics: Adenocarcinoma of Lung; Adult; Aged; Biomarkers, Tumor; Carcinoma, Large Cell; Carcinoma, Squamous Cell; Case-Control Studies; Female; Follow-Up Studies; Humans; Inflammation; Kynurenine; Lung Neoplasms; Male; Middle Aged; Neopterin; Prognosis; Prospective Studies; Risk Factors; Small Cell Lung Carcinoma; Tryptophan	2020
Synthesis and biological evaluation of ¹⁸F-labeled fluoropropyl tryptophan analogs as potential PET probes for tumor imaging. European journal of medicinal chemistry, 2013, Volume: 70 Topics: Animals; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Contrast Media; Fluorine Radioisotopes; Humans; Lung Neoplasms; Mice; Mice, Inbred Strains; Mice, Nude; Molecular Structure; Positron-Emission Tomography; Radiopharmaceuticals; Tissue Distribution; Tryptophan	2013
Circulating biomarkers of tryptophan and the kynurenine pathway and lung cancer risk. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2014, Volume: 23, Issue:3 Topics: Adult; Aged; Biomarkers, Tumor; Case-Control Studies; Cohort Studies; Europe; Female; Humans; Kynurenine; Lung Neoplasms; Male; Middle Aged; Prospective Studies; Risk Factors; Surveys and Questionnaires; Tryptophan	2014
Synthesis and biological evaluation of (18)F-labeled Fluoroethoxy tryptophan analogues as potential PET tumor imaging agents. Molecular pharmaceutics, 2014, Nov-03, Volume: 11, Issue:11 Topics: 5-Hydroxytryptophan; Amino Acid Transport System y+; Amino Acid Transport System y+L; Animals; Cell Line, Tumor; Drug Design; Female; Fluorine Radioisotopes; Humans; Lung Neoplasms; Mice; Mice, Nude; Neoplasm Transplantation; Positron-Emission Tomography; Radiopharmaceuticals; Tryptophan	2014
Selected drugs that inhibit DNA methylation can preferentially kill p53 deficient cells. Oncotarget, 2014, Oct-15, Volume: 5, Issue:19 Topics: Animals; Anticarcinogenic Agents; Azacitidine; Catechin; Cell Line, Tumor; Cell Proliferation; Cytidine; Decitabine; DNA Methylation; Humans; Lung Neoplasms; Mice; Mice, Inbred C57BL; Mice, Knockout; Mutation; Neoplasm Transplantation; Phthalimides; Tryptophan; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays	2014
Inhibition of cancer cell epithelial mesenchymal transition by normal fibroblasts via production of 5-methoxytryptophan. Oncotarget, 2016, May-24, Volume: 7, Issue:21 Topics: A549 Cells; Animals; Cadherins; Cell Line; Coculture Techniques; Epithelial-Mesenchymal Transition; Fibroblasts; Humans; Lung Neoplasms; Mice, SCID; NF-kappa B; p38 Mitogen-Activated Protein Kinases; RNA Interference; Transforming Growth Factor beta1; Tryptophan; Tryptophan Hydroxylase; Vimentin; Xenograft Model Antitumor Assays	2016
Journal of developmental and life-course criminology, 2016, Volume: 2, Issue:2 Topics: Adolescent; Adult; Age Factors; Aged; Amino Acid Substitution; Anemia, Aplastic; Athletes; Athletic Performance; Bone Marrow Transplantation; Carcinoma, Non-Small-Cell Lung; Catalytic Domain; Cell Count; Child; Child, Preschool; Escherichia coli; Female; Gene Expression; Graft Survival; Graft vs Host Disease; Histocompatibility Testing; Humans; Hydrogen Bonding; Immunosuppression Therapy; Inosine Monophosphate; Integrin alphaVbeta3; Kinetics; Knee Joint; Lung Neoplasms; Lymphatic Metastasis; Male; Mediastinal Neoplasms; Middle Aged; Molecular Dynamics Simulation; Muscle, Skeletal; Mutation; Organotechnetium Compounds; Pentosyltransferases; Peptides, Cyclic; Phenylalanine; Plasmodium falciparum; Protein Interaction Domains and Motifs; Protein Structure, Secondary; Protozoan Proteins; Radiopharmaceuticals; Recombinant Proteins; Running; Sensitivity and Specificity; Serine; Siblings; Single Photon Emission Computed Tomography Computed Tomography; Soccer; Structure-Activity Relationship; Substrate Specificity; Thermodynamics; Threonine; Time Factors; Torque; Treatment Outcome; Tryptophan; Tyrosine; Young Adult	2016
De-novo NAD+ synthesis regulates SIRT1-FOXO1 apoptotic pathway in response to NQO1 substrates in lung cancer cells. Oncotarget, 2016, 09-20, Volume: 7, Issue:38 Topics: A549 Cells; Animals; Apoptosis; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Forkhead Box Protein O1; Gene Expression Regulation, Neoplastic; Humans; Large Neutral Amino Acid-Transporter 1; Lung Neoplasms; Mice; Mice, Nude; NAD; NAD(P)H Dehydrogenase (Quinone); Neoplasm Transplantation; Oxidative Stress; Oxygen; Signal Transduction; Sirtuin 1; Tryptophan	2016
Quantification of tryptophan transport and metabolism in lung tumors using PET. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2009, Volume: 50, Issue:3 Topics: Adult; Aged; Carcinoma, Non-Small-Cell Lung; Feasibility Studies; Female; Fluorodeoxyglucose F18; Humans; Lung Neoplasms; Male; Middle Aged; Pilot Projects; Positron-Emission Tomography; Radiopharmaceuticals; Rectal Neoplasms; Tryptophan	2009
Increased serum kynurenine/tryptophan ratio correlates with disease progression in lung cancer. Lung cancer (Amsterdam, Netherlands), 2010, Volume: 67, Issue:3 Topics: Aged; Disease Progression; Female; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Lung Neoplasms; Male; Middle Aged; Prognosis; Tryptophan	2010
Autoregulatory effects of serotonin on proliferation and signaling pathways in lung and small intestine neuroendocrine tumor cell lines. Cancer, 2009, Nov-01, Volume: 115, Issue:21 Topics: Cell Line, Tumor; Cell Proliferation; Homeostasis; Humans; Intestinal Neoplasms; JNK Mitogen-Activated Protein Kinases; Ketanserin; Lung Neoplasms; Mitogen-Activated Protein Kinase 3; Neuroendocrine Tumors; Phosphorylation; Receptors, Serotonin; Serotonin; Signal Transduction; Tryptophan	2009
Melatonin and tryptophan circadian profiles in patients with advanced non-small cell lung cancer. Advances in therapy, 2009, Volume: 26, Issue:9 Topics: Aged; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Case-Control Studies; Circadian Rhythm; Female; Humans; Lung Neoplasms; Male; Melatonin; Middle Aged; Tryptophan	2009
Clinical significance of simultaneous determination of serum tryptophan and tyrosine in patients with lung cancer. Journal of clinical laboratory analysis, 2011, Volume: 25, Issue:4 Topics: Adenocarcinoma; Adenocarcinoma of Lung; Biomarkers, Tumor; Case-Control Studies; Chromatography, High Pressure Liquid; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Sensitivity and Specificity; Tryptophan; Tyrosine	2011
A near-infrared fluorescent probe for monitoring ozone and imaging in living cells. Chemical communications (Cambridge, England), 2012, Jan-18, Volume: 48, Issue:5 Topics: Animals; Carbocyanines; Cell Line, Tumor; Fluorescent Dyes; Half-Life; Humans; Lung Neoplasms; Macrophages; Magnetic Resonance Spectroscopy; Mice; Microscopy, Confocal; Molecular Imaging; Ozone; Reactive Oxygen Species; Sensitivity and Specificity; Spectroscopy, Near-Infrared; Tetradecanoylphorbol Acetate; Tryptophan	2012
Fatigue in patients with lung cancer is related with accelerated tryptophan breakdown. PloS one, 2012, Volume: 7, Issue:5 Topics: Anemia; Biomarkers, Tumor; Fatigue; Female; Humans; Inflammation; Lung Neoplasms; Male; Neoplasm Staging; Psychological Tests; Quality of Life; Tryptophan	2012
The substance P/neurokinin-1 receptor system in lung cancer: focus on the antitumor action of neurokinin-1 receptor antagonists. Peptides, 2012, Volume: 38, Issue:2 Topics: Antineoplastic Agents; Apoptosis; Aprepitant; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Lung Neoplasms; Morpholines; Neurokinin-1 Receptor Antagonists; Piperidines; Receptors, Neurokinin-1; Structure-Activity Relationship; Substance P; Tryptophan; Tumor Cells, Cultured	2012
7-Hydroxytryptophan, a novel, specific, cytotoxic agent for carcinoids and other serotonin-producing tumors. Cancer, 2002, Jun-15, Volume: 94, Issue:12 Topics: 5,6-Dihydroxytryptamine; 5,7-Dihydroxytryptamine; Animals; Antineoplastic Agents; Carcinoid Tumor; Carcinoma, Small Cell; COS Cells; Humans; Lung Neoplasms; Pancreatic Neoplasms; Serotonin; Tryptophan; Tryptophan Hydroxylase; Tumor Cells, Cultured	2002
Large-scale investigation of base excision repair genetic polymorphisms and lung cancer risk in a multicenter study. Journal of the National Cancer Institute, 2005, Apr-20, Volume: 97, Issue:8 Topics: Adenocarcinoma; Adult; Aged; Arginine; Case-Control Studies; Confounding Factors, Epidemiologic; Cysteine; DNA Repair; Europe, Eastern; Female; Genotype; Humans; Logistic Models; Lung Neoplasms; Male; Middle Aged; Multivariate Analysis; Odds Ratio; Polymorphism, Genetic; Research Design; Risk Assessment; Risk Factors; Selection Bias; Serine; Smoking; Tryptophan	2005
Contrasting impact of DNA repair gene XRCC1 polymorphisms Arg399Gln and Arg194Trp on the risk of lung cancer in the north-Indian population. DNA and cell biology, 2007, Volume: 26, Issue:3 Topics: Amino Acid Substitution; Arginine; Case-Control Studies; Codon; DNA Repair; DNA-Binding Proteins; Female; Genotype; Glutamine; Humans; India; Lung Neoplasms; Male; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Population; Risk; Tryptophan; X-ray Repair Cross Complementing Protein 1	2007
Degradation of HPV20E6 by p53: Delta Np63 alpha and mutant p53R248W protect the wild type p53 mediated caspase-degradation. International journal of cancer, 2008, Jul-01, Volume: 123, Issue:1 Topics: Apoptosis; Arginine; Blotting, Western; Carcinoma, Non-Small-Cell Lung; Caspase 3; Cell Line, Tumor; DNA-Binding Proteins; Glutathione Transferase; Humans; Immunoprecipitation; Lung Neoplasms; Mass Spectrometry; Mutation; Oncogene Proteins, Viral; Papillomavirus Infections; Trans-Activators; Transcription Factors; Tryptophan; Tumor Suppressor Protein p53; Tumor Suppressor Proteins; Tumor Virus Infections; Ubiquitin; Vimentin	2008
Interferon regulatory factor 1 tryptophan 11 to arginine point mutation abolishes DNA binding. Biochimica et biophysica acta, 1999, Jul-07, Volume: 1446, Issue:1-2 Topics: Arginine; Carcinoma, Non-Small-Cell Lung; DNA-Binding Proteins; Electrophoresis; Humans; Interferon Regulatory Factor-1; Lung Neoplasms; Phosphoproteins; Point Mutation; Reverse Transcriptase Polymerase Chain Reaction; Transcription Factors; Transcription, Genetic; Transfection; Tryptophan; Tumor Cells, Cultured; Urinary Bladder Neoplasms	1999
Disruption of protein phosphatase 2A subunit interaction in human cancers with mutations in the A alpha subunit gene. Oncogene, 2001, Jan-04, Volume: 20, Issue:1 Topics: Amino Acid Sequence; Arginine; Aspartic Acid; Breast Neoplasms; Female; Glutamic Acid; Glycine; Humans; Lung Neoplasms; Melanoma; Molecular Sequence Data; Neoplasms; Peptide Fragments; Phosphoprotein Phosphatases; Point Mutation; Protein Binding; Protein Phosphatase 2; Protein Structure, Secondary; Tryptophan	2001
Plasma and CSF tryptophan in cancer anorexia. Journal of neural transmission. General section, 1990, Volume: 81, Issue:3 Topics: Aged; Amino Acids; Anorexia; Breast Neoplasms; Feeding and Eating Disorders; Female; Humans; Lung Neoplasms; Male; Middle Aged; Tryptophan	1990
Interferon enhances tryptophan metabolism by inducing pulmonary indoleamine 2,3-dioxygenase: its possible occurrence in cancer patients. Proceedings of the National Academy of Sciences of the United States of America, 1986, Volume: 83, Issue:17 Topics: Cycloheximide; Dactinomycin; Enzyme Induction; In Vitro Techniques; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferons; Liver; Lung; Lung Neoplasms; Oxygenases; Pneumothorax; Tryptophan; Tryptophan Oxygenase	1986
[Chemotherapy of malignant tumors as seen from the aspect of various specific laboratory studies]. Wiener medizinische Wochenschrift (1946), 1967, Oct-07, Volume: 117, Issue:40 Topics: Aged; Blood Proteins; Carcinoma, Bronchogenic; DNA, Neoplasm; Female; Humans; L-Lactate Dehydrogenase; Lung Neoplasms; Male; Neoplasms; Perchlorates; Tryptophan	1967
[Study of the carcinogenic action of tryptophan and certain of its metabolites]. Voprosy onkologii, 1974, Volume: 20, Issue:8 Topics: Adenocarcinoma; Adenofibroma; Animals; Carcinogens; Cystadenoma; Female; Hydroxy Acids; Indoles; Injections, Subcutaneous; Kidney Neoplasms; Leiomyosarcoma; Leukemia, Experimental; Liver Neoplasms; Lung Neoplasms; Lymphoma, Large B-Cell, Diffuse; Male; Mammary Neoplasms, Experimental; Mice; Mice, Inbred C57BL; Neoplasm Metastasis; Neoplasms, Experimental; ortho-Aminobenzoates; Polyps; Rats; Time Factors; Tryptophan; Uterine Neoplasms	1974
[Proceedings: Endogenous carcinogens. Experimental induction of malignant tumors and leukemias by the tryptophan metabolites 3-hydroxyanthranilic acid and 3-hydroxykynurenine]. Zeitschrift fur klinische Chemie und klinische Biochemie, 1972, Volume: 10, Issue:4 Topics: 3-Hydroxyanthranilic Acid; Animals; Carcinoma; Kynurenine; Leukemia, Experimental; Lung Neoplasms; Mice; Neoplasms, Experimental; ortho-Aminobenzoates; Tryptophan; Urinary Bladder Neoplasms	1972
Differences in tryptophan metabolism between breast cancer patients with and without cancer at other sites. Cancer, 1970, Volume: 26, Issue:4 Topics: Bone Neoplasms; Brain Neoplasms; Breast Neoplasms; Female; Humans; Kynurenic Acid; Kynurenine; Lung Neoplasms; Male; Neoplasm Metastasis; Ovarian Neoplasms; Tryptophan; Urinary Bladder Neoplasms; Xanthurenates	1970
Carcinoid tumors and the carcinoid syndrome. Journal of the American Geriatrics Society, 1969, Volume: 17, Issue:8 Topics: Adult; Aged; Bradykinin; Carcinoid Tumor; Female; Gastrointestinal Neoplasms; Humans; Kinins; Lung Neoplasms; Male; Malignant Carcinoid Syndrome; Middle Aged; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Norepinephrine; Phenylalanine; Serotonin; Tryptophan; Tyramine	1969