tryptophan and Huntington Disease

tryptophan has been researched along with Huntington Disease in 33 studies

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-199010 (30.30)18.7374
1990's7 (21.21)18.2507
2000's7 (21.21)29.6817
2010's7 (21.21)24.3611
2020's2 (6.06)2.80

Authors

AuthorsStudies
Fathi, M; Hajibeygi, R; Jazi, K; Klegeris, A; McElhinney, A; Sayehmiri, F; Shool, S; Sodeifian, F; Tavasol, A; Tavirani, MR; Vakili, K; Yaghoobpoor, S1
Tanaka, M; Toldi, J; Vécsei, L1
Breda, C; Giorgini, F; Sathyasaikumar, KV; Schwarcz, R1
Adomat, H; Budac, DP; Leavitt, BR; Lu, G; Mazarei, G; Möller, T; Tomlinson Guns, ES1
Leavitt, BR; Mazarei, G1
Costantino, G1
Guidetti, P; Muchowski, PJ; Sathyasaikumar, KV; Schwarcz, R1
Amori, L; Guidetti, P; Muchowski, PJ; Sathyasaikumar, KV; Schwarcz, R; Stachowski, EK1
Breda, C; Campesan, S; Giorgini, F; Green, EW; Kyriacou, CP; Muchowski, PJ; Sathyasaikumar, KV; Schwarcz, R1
Tan, L; Yu, JT1
Bader, M; Bauer, A; Bauer, I; Grasshoff, U; Holzmann, C; Jones, L; Kask, A; Kobbe, P; Krotova, J; Landwehrmeyer, B; Li, XJ; Lindenberg, KS; Nguyen, HP; Pabst, R; Paul, M; Rathke-Hartlieb, S; Riess, O; Schmidt, T; Schmitt, I; Schulz, JB; Stiller, D; Vaarmann, A; Vieira-Saecker, AM; von Hörsten, S; Walther, T1
Clark, CJ; Darlington, LG; Forrest, CM; Mackay, GM; Stone, TW1
Christofides, J; Darlington, LG; Egerton, M; Forrest, CM; Mackay, GM; Stone, TW; Stoy, N1
Bridel, M; Christofides, J; Darlington, LG; Egerton, M; Forrest, CM; Mackay, GM; Stone, TW; Stoy, N1
Kato, Y; Kurita, J; Miyakawa, T; Tanokura, M1
Perez-De La Cruz, V; Santamaria, A1
Belendiuk, GW; Belendiuk, K; Freedman, DX1
Pearson, SJ; Reynolds, GP2
Pascoe, M1
Benitez, J; Díaz Neira, W; García de Yebenes, J; García Ruiz, PJ; Gimenez Roldan, S; Mena, MA; Sanchez Bernardos, V1
Fuchs, D; Jellinger, K; Laccone, F; Leblhuber, F; Tilz, GP; Walli, J; Widner, B1
Demel, U; Fuchs, D; Leblhuber, F; Tilz, GP; Walli, J; Widner, B1
Curzon, G; Kantamaneni, BD1
Bird, ED; Phillipson, OT1
Growdon, JH; Wurtman, RJ1
Beal, MF; Bird, ED; Matson, WR; Milbury, P; Ogawa, T; Ryan, EA; Storey, E1
Beal, MF; Bird, ED; Gamache, PH; Matson, WR; Swartz, KJ1
Oepen, H; Oepen, I1
Ottosson, JO; Rapp, W1
Horne, DJ; McLeod, WR1
Davidson, D; Magill, BE; Murray, LG; Pullar, IA; Wilson, H; Yates, CM1
Chase, TN; Murphy, DL; Pérez-Cruet, J1

Reviews

9 review(s) available for tryptophan and Huntington Disease

ArticleYear
Dynamic changes in metabolites of the kynurenine pathway in Alzheimer's disease, Parkinson's disease, and Huntington's disease: A systematic Review and meta-analysis.
    Frontiers in immunology, 2022, Volume: 13

    Topics: 3-Hydroxyanthranilic Acid; Adenosine; Alzheimer Disease; Humans; Huntington Disease; Hydroxyindoleacetic Acid; Kynurenic Acid; Kynurenine; NAD; Niacinamide; Parkinson Disease; Tryptophan

2022
Exploring the Etiological Links behind Neurodegenerative Diseases: Inflammatory Cytokines and Bioactive Kynurenines.
    International journal of molecular sciences, 2020, Mar-31, Volume: 21, Issue:7

    Topics: Alzheimer Disease; Anti-Inflammatory Agents; Biomarkers; Cytokines; Humans; Huntington Disease; Inflammation; Kynurenine; Neurodegenerative Diseases; Parkinson Disease; Reactive Oxygen Species; Tryptophan

2020
Indoleamine 2,3 Dioxygenase as a Potential Therapeutic Target in Huntington's Disease.
    Journal of Huntington's disease, 2015, Volume: 4, Issue:2

    Topics: Alzheimer Disease; Animals; Humans; Huntington Disease; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Parkinson Disease; Signal Transduction; Tryptophan

2015
New promises for manipulation of kynurenine pathway in cancer and neurological diseases.
    Expert opinion on therapeutic targets, 2009, Volume: 13, Issue:2

    Topics: Animals; Drug Delivery Systems; Drug Discovery; Humans; Huntington Disease; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Neoplasms; Schizophrenia; Tryptophan

2009
Of mice, rats and men: Revisiting the quinolinic acid hypothesis of Huntington's disease.
    Progress in neurobiology, 2010, Feb-09, Volume: 90, Issue:2

    Topics: Animals; Disease Models, Animal; Dopamine; Humans; Huntington Disease; Kynurenine; Mice; Mutation; Peptides; Quinolinic Acid; Rats; Receptors, Glutamate; Serotonin Plasma Membrane Transport Proteins; Tryptophan

2010
The kynurenine pathway in neurodegenerative diseases: mechanistic and therapeutic considerations.
    Journal of the neurological sciences, 2012, Dec-15, Volume: 323, Issue:1-2

    Topics: Aging; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Animals; Enzyme Inhibitors; Humans; Huntington Disease; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inflammation; Kynurenic Acid; Kynurenine; Microglia; Molecular Targeted Therapy; Neurodegenerative Diseases; Neurons; Neuroprotective Agents; Neurotoxins; Parkinson Disease; Quinolinic Acid; Receptors, G-Protein-Coupled; Receptors, N-Methyl-D-Aspartate; Tryptophan

2012
Tryptophan metabolites and brain disorders.
    Clinical chemistry and laboratory medicine, 2003, Volume: 41, Issue:7

    Topics: AIDS Dementia Complex; Brain Diseases; Central Nervous System Diseases; Humans; Huntington Disease; Kynurenine; Quinolinic Acid; Tryptophan

2003
Integrative hypothesis for Huntington's disease: a brief review of experimental evidence.
    Physiological research, 2007, Volume: 56, Issue:5

    Topics: Animals; Calcium; Cell Death; Disease Models, Animal; Energy Metabolism; Excitatory Amino Acids; Humans; Huntington Disease; Inflammation; Kynurenic Acid; Mice; Mice, Transgenic; Mutation; Neurons; Nitro Compounds; Oxidative Stress; Propionates; Quinolinic Acid; Serotonin Plasma Membrane Transport Proteins; Trinucleotide Repeats; Tryptophan

2007
Neurochemical-clinical correlates in Huntington's disease--applications of brain banking techniques.
    Journal of neural transmission. Supplementum, 1993, Volume: 39

    Topics: Brain Chemistry; Humans; Huntington Disease; Neurotransmitter Agents; Tissue Banks; Tryptophan

1993

Trials

1 trial(s) available for tryptophan and Huntington Disease

ArticleYear
Dietary enhancement of CNS neurotransmitters.
    Hospital practice, 1978, Volume: 13, Issue:3

    Topics: Acetylcholine; Administration, Oral; Brain; Choline; Clinical Trials as Topic; Diet; Dyskinesia, Drug-Induced; Humans; Huntington Disease; Physostigmine; Serotonin; Tryptophan

1978

Other Studies

23 other study(ies) available for tryptophan and Huntington Disease

ArticleYear
Assessing and Modulating Kynurenine Pathway Dynamics in Huntington's Disease: Focus on Kynurenine 3-Monooxygenase.
    Methods in molecular biology (Clifton, N.J.), 2018, Volume: 1780

    Topics: Aged; Animals; Brain; Disease Models, Animal; Enzyme Inhibitors; Female; Humans; Huntingtin Protein; Huntington Disease; Kynurenine; Kynurenine 3-Monooxygenase; Male; Metabolic Networks and Pathways; Middle Aged; Neuroprotective Agents; Tryptophan

2018
Age-dependent alterations of the kynurenine pathway in the YAC128 mouse model of Huntington disease.
    Journal of neurochemistry, 2013, Volume: 127, Issue:6

    Topics: Aging; Animals; Brain; Cerebellum; Corpus Striatum; Female; Genotype; Huntington Disease; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Male; Mice; Quinolinic Acid; Serotonin; Signal Transduction; Tryptophan; Tryptophan Oxygenase

2013
Dysfunctional kynurenine pathway metabolism in the R6/2 mouse model of Huntington's disease.
    Journal of neurochemistry, 2010, Volume: 113, Issue:6

    Topics: Age Factors; Animals; Brain; Chromatography, High Pressure Liquid; Disease Models, Animal; Female; Huntingtin Protein; Huntington Disease; Kynurenine; Metabolic Diseases; Metabolic Networks and Pathways; Mice; Mice, Inbred C57BL; Mice, Transgenic; Nerve Tissue Proteins; Nuclear Proteins; Time Factors; Tritium; Tryptophan

2010
The kynurenine pathway modulates neurodegeneration in a Drosophila model of Huntington's disease.
    Current biology : CB, 2011, Jun-07, Volume: 21, Issue:11

    Topics: Animals; Animals, Genetically Modified; Disease Models, Animal; Drosophila melanogaster; Huntington Disease; Kynurenic Acid; Kynurenine; Kynurenine 3-Monooxygenase; Nerve Degeneration; Neuroprotective Agents; Tryptophan; Tryptophan Oxygenase

2011
Transgenic rat model of Huntington's disease.
    Human molecular genetics, 2003, Mar-15, Volume: 12, Issue:6

    Topics: Animals; Animals, Genetically Modified; Cell Nucleus; Disease Models, Animal; Disease Progression; DNA, Complementary; Glucose; Huntingtin Protein; Huntington Disease; Immunohistochemistry; Magnetic Resonance Imaging; Models, Genetic; Nerve Tissue Proteins; Neurons; Nuclear Proteins; Phenotype; Promoter Regions, Genetic; Rats; Time Factors; Tissue Distribution; Tomography, Emission-Computed; Transgenes; Trinucleotide Repeat Expansion; Tryptophan

2003
Tryptophan metabolism and oxidative stress in patients with Huntington's disease.
    Journal of neurochemistry, 2005, Volume: 93, Issue:3

    Topics: Adolescent; Adult; Aged; Aldehydes; Brain; Female; Humans; Huntington Disease; Kynurenine; Male; Malondialdehyde; Middle Aged; Neopterin; Nerve Growth Factors; Oxidative Stress; S100 Calcium Binding Protein beta Subunit; S100 Proteins; Tryptophan

2005
Blood 5-hydroxytryptamine, 5-hydroxyindoleacetic acid and melatonin levels in patients with either Huntington's disease or chronic brain injury.
    Journal of neurochemistry, 2006, Volume: 97, Issue:4

    Topics: Administration, Oral; Aged; Biomarkers; Brain; Brain Injury, Chronic; Down-Regulation; Female; Food, Formulated; Humans; Huntington Disease; Hydroxyindoleacetic Acid; Lipid Peroxidation; Male; Melatonin; Middle Aged; Neopterin; Oxidative Stress; Reference Values; Serotonin; Tryptophan; Up-Regulation

2006
Structure of FBP11 WW1-PL ligand complex reveals the mechanism of proline-rich ligand recognition by group II/III WW domains.
    The Journal of biological chemistry, 2006, Dec-29, Volume: 281, Issue:52

    Topics: Amino Acid Motifs; Carrier Proteins; Humans; Huntington Disease; Leucine; Ligands; Magnetic Resonance Spectroscopy; Peptides; Proline; Proline-Rich Protein Domains; Protein Structure, Tertiary; Rett Syndrome; Ribonucleoprotein, U1 Small Nuclear; Saccharomyces cerevisiae Proteins; Sequence Homology, Amino Acid; Tryptophan

2006
Blood monoamine metabolism in Huntington's disease.
    Archives of general psychiatry, 1980, Volume: 37, Issue:3

    Topics: Adolescent; Adult; Aged; Blood Platelets; Central Nervous System; Dopamine; Epinephrine; Female; Humans; Huntington Disease; Male; Middle Aged; Monoamine Oxidase; Neurotransmitter Agents; Norepinephrine; Serotonin; Tryptophan

1980
Huntington's disease and low tryptophan diet.
    Medical hypotheses, 1993, Volume: 41, Issue:4

    Topics: Brain; Female; Humans; Huntington Disease; Models, Biological; Nerve Degeneration; Quinolinic Acid; Tryptophan

1993
Cerebrospinal fluid homovanillic acid is reduced in untreated Huntington's disease.
    Clinical neuropharmacology, 1995, Volume: 18, Issue:1

    Topics: Adolescent; Adult; Female; Homovanillic Acid; Humans; Huntington Disease; Hydroxyindoleacetic Acid; Male; Middle Aged; Tryptophan

1995
Activated immune system in patients with Huntington's disease.
    Clinical chemistry and laboratory medicine, 1998, Volume: 36, Issue:10

    Topics: Adult; Antigens, CD; Complement C3; Female; Humans; Huntington Disease; Immunoglobulins; Kynurenine; Male; Middle Aged; Neopterin; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Type I; Tryptophan

1998
Degradation of tryptophan in neurodegenerative disorders.
    Advances in experimental medicine and biology, 1999, Volume: 467

    Topics: Alzheimer Disease; Biomarkers; Humans; Huntington Disease; Intellectual Disability; Interleukin-2; Kynurenine; Neopterin; Receptors, Interleukin-2; Receptors, Tumor Necrosis Factor; Tryptophan; Tumor Necrosis Factor-alpha

1999
Transmitters and related substances in brain material: an index of terminal and/or post-mortem biochemical change.
    Lancet (London, England), 1978, Jan-21, Volume: 1, Issue:8056

    Topics: Brain; Carboxy-Lyases; Cauda Equina; Glutamate Decarboxylase; Humans; Huntington Disease; Neurotransmitter Agents; Nucleus Accumbens; Postmortem Changes; Schizophrenia; Tryptophan

1978
Plasma glucose, non-esterified fatty acids and amino acids in Huntington's chorea.
    Clinical science and molecular medicine, 1977, Volume: 52, Issue:3

    Topics: Amino Acids; Blood Glucose; Fasting; Fatty Acids, Nonesterified; Glucose; Glucose Tolerance Test; Humans; Huntington Disease; Insulin; Serum Albumin; Tryptophan

1977
Kynurenic acid concentrations are reduced in Huntington's disease cerebral cortex.
    Journal of the neurological sciences, 1992, Volume: 108, Issue:1

    Topics: Aged; Alzheimer Disease; Cerebral Cortex; Energy Metabolism; Free Radicals; Humans; Huntington Disease; Kynurenic Acid; Kynurenine; Middle Aged; Parkinson Disease; Purines; Tryptophan; Tyrosine

1992
Kynurenine pathway measurements in Huntington's disease striatum: evidence for reduced formation of kynurenic acid.
    Journal of neurochemistry, 1990, Volume: 55, Issue:4

    Topics: Aged; Autopsy; Corpus Striatum; Female; Humans; Huntington Disease; Kynurenic Acid; Kynurenine; Male; Middle Aged; Putamen; Reference Values; Tryptophan; Tyrosine

1990
Increased brain 3-hydroxykynurenine in Huntington's disease.
    Lancet (London, England), 1989, Oct-21, Volume: 2, Issue:8669

    Topics: Brain Chemistry; Cerebral Cortex; Humans; Huntington Disease; Kynurenine; Tryptophan

1989
[Tryptophan loading test in Huntington's chorea].
    Humangenetik, 1969, Volume: 7, Issue:3

    Topics: Adolescent; Adult; Amino Acids; Chromatography, Ion Exchange; Female; Humans; Huntington Disease; Male; Middle Aged; Tryptophan

1969
Serum levels of phenylalanine and tyrosine in Huntington's chorea.
    Acta psychiatrica Scandinavica. Supplementum, 1971, Volume: 221

    Topics: Adult; Aged; Analysis of Variance; Antidepressive Agents; Body Weight; Dopamine; Female; Humans; Huntington Disease; Male; Middle Aged; Norepinephrine; Parasympatholytics; Phenylalanine; Psychotic Disorders; Reserpine; Schizophrenia; Tryptophan; Tyrosine

1971
Huntington's chorea and tryptophan.
    Journal of neurology, neurosurgery, and psychiatry, 1972, Volume: 35, Issue:4

    Topics: Extrapyramidal Tracts; Humans; Huntington Disease; Motor Skills; Pyridoxine; Serotonin; Tryptophan

1972
Lysosomal enzymes, amino acids and acid metabolites of amines in Huntington's chorea.
    Clinica chimica acta; international journal of clinical chemistry, 1973, Feb-28, Volume: 44, Issue:1

    Topics: Acid Phosphatase; Adult; Aged; Amines; Amino Acids; Blood Proteins; Cerebrospinal Fluid Proteins; Dopamine; Female; Humans; Huntington Disease; Hydroxyindoleacetic Acid; Lysosomes; Male; Middle Aged; Phenylacetates; Serotonin; Sulfatases; Tryptophan; Tyrosine

1973
Dietary regulation of brain tryptophan metabolism by plasma ratio of free tryptophan and neutral amino acids in humans.
    Nature, 1974, Apr-19, Volume: 248, Issue:5450

    Topics: Amino Acids; Blood Proteins; Brain; Diet; Eating; Fasting; Feeding Behavior; Humans; Huntington Disease; Hydroxyindoleacetic Acid; Parkinson Disease; Protein Binding; Tryptophan

1974