Compounds > tryptophan

tryptophan and HIV Coinfection

tryptophan has been researched along with HIV Coinfection in 91 studies

Research

Studies (91)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's10 (10.99)18.2507
2000's16 (17.58)29.6817
2010's40 (43.96)24.3611
2020's25 (27.47)2.80

Authors

AuthorsStudies
Barve, S; Bryant, K; Bryant, V; Cohen, R; Cook, RL; Gautam, S; Ghare, S; Ghooray, D; Govind, V; Hoffman, K; McClain, CJ; Petrosino, J; Reyes-Vega, A; Singhal, R; Srisailam, PK; Tirumala, CC1
Groves, N; Haider, T; Jolly, C; Mesner, D; Snetkov, X; van Engelenburg, SB1
Benfield, T; Gelpi, M; Hansen, SH; Hov, JR; Høgh, J; Kofoed, KF; Midttun, Ø; Nielsen, SD; Raju, SC; Trøseid, M; Ueland, PM; Ueland, T; Vestad, B1
Mannan, A; Prabhakar, NK; Sharma, VK; Singh, TG1
Björkman, P; Jansson, M; Mulleta, D; Olsson, O; Skogmar, S; Tesfaye, F1
Anastos, K; Bullock, K; Burgess, HJ; Clish, C; French, AL; Gustafson, D; Morack, R; Qi, Q; Rogando, AC; Sharma, A; Weber, KM; Xing, J; Xue, X; Yohannes, T1
Carrico, AW; Chavez, JV; Cherenack, EM; Ghanooni, D; Klatt, NR; McIntosh, R; Paul, RH; Rubin, LH1
Feng, XY; Gan, HL; Jin, HL; Wang, M; Yuan, ZW; Zhang, J; Zhou, HP1
Cao, H; Chen, X; Gao, X; Gong, Z; Huang, P; Huang, Y; Li, Y; Lun, J; Zhou, B; Zhou, C; Zou, J1
Alisjahbana, B; Ardiansyah, E; Avila-Pacheco, J; Bang, ND; Bullock, K; Chau, TTH; Clish, CB; Dian, S; Donovan, J; Estiasari, R; Ganiem, AR; Hai, HT; Hamers, RL; Heemskerk, D; Imran, D; Koeken, VACM; Kumar, V; Maharani, K; Netea, MG; Nhat, LTH; Ruslami, R; Thuong, NTT; Thwaites, G; Tram, TTB; van Crevel, R; van Laarhoven, A; Vinh, DN1
Basrur, V; Carrington, M; Cieslik, M; Grigorova, I; Kaur, A; Mumphrey, MB; Nesvizhskii, AI; Raghavan, M; Surnilla, A; Zaitouna, AJ1
Belin de Chantemèle, E; Bensreti, H; Elengickal, A; Hamrick, MW; McGee-Lawrence, ME; Sultana, S1
Gelpi, M; Lebech, AM; Lundgren, J; Midttun, Ø; Mocroft, A; Nielsen, SD; Trøseid, M; Ueland, PM; Ullum, H1
Guaraldi, G; Milic, J1
Adu-Gyamfi, CG; George, JA; Savulescu, D; Suchard, MS1
Chen, J; Han, Y; Jin, X; Li, T; Lu, H; Ma, L; Qiu, X; Sun, L; Sun, WW; Wang, JH; Zhao, QX; Zhou, YH1
Colson, P; Delerce, J; Dhiver, C; Gaudin, M; Glazunova, OO; Levasseur, A; Raoult, D; Tamalet, C1
Carrico, AW; Chahine, A; Cohn, M; Dilworth, SE; Fuchs, D; Gouse, H; Lee, J; Lee, JY; Magidson, JF; Meade, CS1
Adu-Gyamfi, CG; Chaisson, R; Darboe, F; Fisher, M; George, JA; Hoffmann, C; Makhathini, L; Martinson, N; Otwombe, K; Penn-Nicholson, A; Savulescu, D; Scriba, TJ; Snyman, T; Suchard, MS1
Ahn, H; Aweeka, FT; Beck-Engeser, G; Deeks, SG; Deitchman, AN; Hartig, H; Hecht, FM; Hunt, PW; Martin, JN; Schnittman, SR; York, VA1
Carrico, AW; Dilworth, SE; Feaster, DJ; Fuchs, D; Glynn, TR; Lee, JY; Moskowitz, JT; Neilands, TB; Rodriguez, A1
Drivsholm, N; Faurholt-Jepsen, M; Gelpi, M; Kirkegaard-Klitbo, DM; Knudsen, AD; Midttun, Ø; Nielsen, SD; Trøseid, M; Ueland, PM1
Adu-Gyamfi, C; Chaisson, R; George, J; Martinson, N; Mikhathani, L; Otwombe, K; Salazar-Austin, N; Savulescu, D; Suchard, M1
Carrico, AW; Dilworth, SE; Flentje, A; Fuchs, D; Moskowitz, JT; Neilands, TB; Vincent, W1
Abdelnabi, R; Boonen, A; Camarasa, MJ; Gago, F; Illescas, BM; Martí-Marí, O; Martín, N; Mills, A; Neyts, J; Noppen, S; Ruiz-Santaquiteria, M; San-Félix, A; Schols, D1
Cheng, D; Emenyonu, N; Forman, LS; Hahn, JA; Huang, Y; Hunt, PW; Muyindike, W; Ngabirano, C; Pierre, F; Samet, J; So-Armah, K; Winter, M1
Douglas, SD; Evans, DL; Kinder, A; Pappa, V; Rappaport, J; Spitsin, S1
Bangsberg, DR; Boum, Y; Burdo, TH; Byakwaga, H; Cao, H; Haberer, JE; Huang, Y; Hunt, PW; Kembabazi, A; Lederman, MM; Lee, S; Martin, JN; Tracy, RP; Williams, KC1
Gelpi, M; Hartling, HJ; Nielsen, SD; Trøseid, M; Ueland, PM; Ullum, H1
Abdullah, NK; Azwa, I; Chong, ML; Crisci, E; Kamarulzaman, A; Larsson, M; Leong, KH; McStea, M; Rajasuriar, R; Takayama, K; Woo, YL; Yap, SH1
Anastos, K; Burk, RD; Clish, CB; Glesby, MJ; Haberlen, SA; Hanna, DB; Hodis, HN; Hua, S; Kaplan, RC; Landay, AL; Lazar, JM; Post, WS; Qi, Q; Scott, JM; Shah, SJ; Wang, T1
Aukrust, P; Gaardbo, JC; Gelpi, M; Gerstoft, J; Hoel, H; Holm, K; Hov, JR; Hove-Skovsgaard, M; Kummen, M; Nielsen, SD; Nwosu, F; Rudi, K; Seljeflot, I; Trøseid, M; Ueland, PM; Ullum, H; Valeur, J1
Chen, J; Ji, Y; Liu, L; Lu, H; Mehraj, V; Ponte, R; Qi, T; Routy, JP; Shen, Y; Wang, Z; Xun, J; Yang, J; Zhang, R1
Boasso, A; Fuchs, D; Higgs, C; Keegan, MR; Nelson, M; Winston, A1
Dai, X; Dong, X; Guo, Y; Hu, C; Huang, Y; Su, J; Wang, M; Zhou, Q; Zhu, B1
Fordyce, J; García, AA; Harrison, ML; Rock, J; Wolfe, AS; Zuñiga, JA1
Chen, Y; Dai, S; Gordon, J; Kearns, AC; Lehmicke, G; Liu, F; Qin, X; Rappaport, J; Velasquez, S1
Barboni, L; Graham, D; Liao, Z; Nzowa, LK; Tapondjou, LA; Teponno, RB; Verotta, L; Zink, MC1
Gee, W; Huang, Y; Hunt, PW; Louie, A; Massenkoff, N; Xu, C; Yang, Q1
Albright, RG; Broadhurst, MJ; Deeks, SG; Dunham, RM; Hernandez, RD; Huang, Y; Hunt, PW; Iwai, S; Lederman, MM; Lynch, SV; Maher, MC; McCune, JM; Somsouk, M; Vujkovic-Cvijin, I1
Ancuta, P; Gilmore, N; Jenabian, MA; Kanagaratham, C; Kema, I; Lapointe, R; Patel, M; Radzioch, D; Routy, JP; Thébault, P; Tremblay, C1
Bangsberg, DR; Haberer, JE; Huang, Y; Hunt, PW; Kembabazi, A; Martin, JN; Martinez, P; Muzoora, C; Tsai, AC; Weiser, SD1
Bangsberg, DR; Bennett, J; Boum, Y; Byakwaga, H; Cao, H; Deeks, SG; Haberer, JE; Huang, Y; Hunt, PW; Kembabazi, A; Martin, JN; McCune, JM; Muzoora, C; Weiser, SD1
Ancuta, P; Gilmore, N; Jenabian, MA; Kanagaratham, C; Kema, I; Lapointe, R; Patel, M; Radzioch, D; Routy, JP; Thébault, P; Tremblay, C; Vyboh, K1
Cai, R; Chen, J; Liu, L; Lu, H; Qi, T; Shao, J; Shen, Y; Zhang, R1
Ahmad, A; Allam, O; Ancuta, P; Baril, JG; Costiniuk, CT; El-Far, M; Jenabian, MA; Kanagaratham, C; Kema, I; LeBlanc, R; Lebouché, B; Radzioch, D; Routy, JP; Thomas, R; Tremblay, C; Vyboh, K1
Jenabian, MA; Mehraj, V; Routy, JP; Vyboh, K1
Bipath, P; Levay, PF; Viljoen, M2
Dagenais-Lussier, X; El-Far, M; Grevenynghe, Jv; Mouna, A; Routy, JP; Sekaly, RP; Tremblay, C1
Costiniuk, CT; Jenabian, MA; Kema, I; Klein, MB; Mehraj, V; Paulino Ramirez, R; Rollet, K; Routy, JP; Vyboh, K1
Gaardbo, JC; Midttun, Ø; Nielsen, SD; Stiksrud, B; Trøsied, M; Ueland, PM; Ullum, H1
Byakwaga, H; Haas, DW; Huang, Y; Hunt, PW; Kroetz, DL; Kubo, M; Lee, SA; Martin, JN; Mclaren, PJ; Mefford, JA; Mushiroda, T; Witte, JS1
Alam, SM; Bouton-Verville, H; Bowman, CM; Bradley, T; Everitt, JI; Fox, CB; Haynes, BF; Holl, TM; Ilkayeva, O; Kelsoe, G; Kepler, TB; Liao, HX; McLendon, R; Moody, MA; Newgard, CB; Parks, R; Reed, SG; Santra, S; Scearce, RM; Sutherland, LL; Vandergrift, N; Verkoczy, L; Yang, G; Zhang, J; Zhang, R1
Avelino-Silva, VI; Caiaffa-Filho, HH; Cerqueira, NB; Costa, DA; Dias, JZ; Freire, MS; Hong, MA; Huang, Y; Hunt, PW; Kallas, EG; Lima, SB; Miyaji, KT; Nishiya, AS; Sabino, EC; Sartori, AM; Simoes, M1
Balzarini, J; Camarasa, MJ; Flores, A; Leyssen, P; Liekens, S; Martínez-Gualda, B; Mirabelli, C; Neyts, J; Noppen, S; Quesada, E; Rivero-Buceta, E; San-Félix, A; Schols, D; Sun, L1
Anderson, SA; Boasso, A; Dolan, MJ; Hardy, AW; Shearer, GM1
Carrico, AW; Fuchs, D; Hecht, FM; Johnson, MO; Morin, SF; Remien, RH; Riley, ED1
Taylor, EW1
Murray, MF2
Aweeka, F; Barbour, JD; Brenchley, JM; Deeks, SG; Douek, DC; Favre, D; Hecht, FM; Huang, Y; Hunt, PW; Jayawardene, A; Kanwar, B; Loke, P; Lowe, MM; Martin, JN; McCune, JM; Mold, J; Seu, L1
Leal, E; Villanova, FE1
Antunes, AM; Beland, FA; Coelho, AV; Godinho, AL; Gomes, RA; Marques, MM; Martins, IL; Oliveira, MC1
Boasso, A1
Bosire, R; Brown, ER; Choi, RY; Farquhar, C; Fowke, KR; John-Stewart, G; Juno, J; Lohman-Payne, B; Oyugi, JO1
Boasso, A; Doster, MN; Fenizia, C; Franchini, G; Fuchs, D; Heraud, JM; Hryniewicz, A; Morgan, T; Shearer, GM; Vaccari, M; Weiss, D1
Chai, Y; Chen, Q; Dong, X; Liao, W; Lou, Z; Pan, W; Tan, G; Zhang, W; Zhu, Z1
Foster, HD1
Fuchs, D; Neurauter, G; Quirchmair, G; Sarcletti, M; Widner, B; Zangerle, R1
Chrastil, J; Dou, H; Gendelman, HE; Heilman, D; Knipe, B; Munn, DH; Persidsky, Y; Poluektova, L; Potula, R; Takikawa, O1
Anderson, SA; Boasso, A; Dolan, MJ; Fuchs, D; Hardy, AW; Herbeuval, JP; Shearer, GM1
Allegri, G; Bertazzo, A; Comai, S; Costa, CV; Longatti, P; Perin, A; Rizzo, V1
Boasso, A; Shearer, GM1
Bellmann-Weiler, R; Fuchs, D; Garimorth, K; Schroecksnadel, K; Weiss, G; Zangerle, R1
Bechmann, I; Kwidzinski, E1
Brosnan, CF; Choi, S; Connolly, E; Lee, SC; Rivieccio, M; Suh, HS; Takikawa, O; Zhao, ML; Zhao, Y1
Fuchs, D; Kemmler, G; Mumelter, B; Sarcletti, M; Schroecksnadel, K; Weiss, G; Winkler, C; Zangerle, R1
Fuchs, D; Gisslén, M; Hagberg, L; Larsson, M; Norkrans, G; Wachter, H2
Dursun, SM1
Anderson, JL; Arnold, E; Birch, C; Deacon, NJ; Gurusinghe, AD; Hooker, DJ; Land, S; Roy, BM; Solomon, AE; Tachedjian, G1
Brown, RR1
Eriksson, T; Lidberg, L1
de Sá, M; DeLeys, RJ; Saman, E; Van Eynde, G; Van Geel, A; Vanden Haesevelde, M; Vanderborght, B1
Allen, RH; Altfeld, M; Kreuzer, KA; Look, MP; Riezler, R; Rockstroh, JK; Sauerbruch, T; Stabler, SP1
Hervé, P; Humbert, M; Nunes, H; Parent, F; Simonneau, G; Sitbon, O1
Jones, DR; Piller, SC; Suzuki, K1
Fuchs, D; Holsboer, F; Krieg, JC; Möller, AA; Schreiber, W; Wachter, H; Wiegand, M1
Dierich, MP; Fuchs, D; Möller, AA; Reibnegger, G; Wachter, H; Werner, ER; Werner-Felmayer, G1
Forsman, A; Fuchs, D; Hagberg, L; Larsson, M; Norkrans, G; Reibnegger, G; Wachter, H; Werner, ER1

Reviews

13 review(s) available for tryptophan and HIV Coinfection

ArticleYear
Kynurenine Metabolism and Alzheimer's Disease: The Potential Targets and Approaches.
    Neurochemical research, 2022, Volume: 47, Issue:6

    Topics: Alzheimer Disease; HIV Infections; Humans; Kynurenine; Oxidative Stress; Tryptophan

2022
Through the Looking-Glass: Psychoneuroimmunology and the Microbiome-Gut-Brain Axis in the Modern Antiretroviral Therapy Era.
    Psychosomatic medicine, 2022, 10-01, Volume: 84, Issue:8

    Topics: Brain; Brain-Gut Axis; Gastrointestinal Microbiome; HIV Infections; Humans; Hypothalamo-Hypophyseal System; Oxytocin; Pituitary-Adrenal System; Psychoneuroimmunology; Tryptophan

2022
The kynurenine pathway in HIV, frailty and inflammaging.
    Frontiers in immunology, 2023, Volume: 14

    Topics: Aged; Cytokines; Frailty; HIV Infections; Humans; Kynurenine; Tryptophan

2023
Indoleamine 2, 3-Dioxygenase-Mediated Tryptophan Catabolism: A Leading Star or Supporting Act in the Tuberculosis and HIV Pas-de-Deux?
    Frontiers in cellular and infection microbiology, 2019, Volume: 9

    Topics: Animals; Biomarkers; Disease Susceptibility; Energy Metabolism; Enzyme Activation; Female; Gene Expression; HIV Infections; Host-Pathogen Interactions; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Male; Tryptophan; Tuberculosis

2019
HIV and the gut microbiota, partners in crime: breaking the vicious cycle to unearth new therapeutic targets.
    Journal of immunology research, 2015, Volume: 2015

    Topics: Animals; Gastrointestinal Microbiome; Gastrointestinal Tract; HIV Infections; Host-Pathogen Interactions; Humans; Immune System; Immunotherapy; Intestinal Mucosa; Metabolic Networks and Pathways; Tryptophan

2015
Current topics in HIV-1 pathogenesis: The emergence of deregulated immuno-metabolism in HIV-infected subjects.
    Cytokine & growth factor reviews, 2015, Volume: 26, Issue:6

    Topics: Adaptive Immunity; Adult; Cytokines; Glucose; HIV Infections; HIV-1; Humans; Immunity, Innate; Inflammation; Lipid Metabolism; Oxidative Stress; T-Lymphocytes; Tryptophan; Viral Proteins

2015
Wounding the immune system with its own blade: HIV-induced tryptophan catabolism and pathogenesis.
    Current medicinal chemistry, 2011, Volume: 18, Issue:15

    Topics: Animals; HIV; HIV Infections; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Tryptophan

2011
Tryptophan depletion and HIV infection: a metabolic link to pathogenesis.
    The Lancet. Infectious diseases, 2003, Volume: 3, Issue:10

    Topics: Anti-HIV Agents; HIV Infections; Humans; Niacinamide; Tryptophan

2003
How does indoleamine 2,3-dioxygenase contribute to HIV-mediated immune dysregulation.
    Current drug metabolism, 2007, Volume: 8, Issue:3

    Topics: Animals; HIV Infections; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; T-Lymphocytes, Regulatory; Tryptophan

2007
Indoleamine-2, 3-dioxygenase and other interferon-gamma-mediated pathways in patients with human immunodeficiency virus infection.
    Current drug metabolism, 2007, Volume: 8, Issue:3

    Topics: HIV Infections; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferon-gamma; Neopterin; Tryptophan

2007
IDO expression in the brain: a double-edged sword.
    Journal of molecular medicine (Berlin, Germany), 2007, Volume: 85, Issue:12

    Topics: Animals; Brain; Candidiasis; Cytomegalovirus Infections; Encephalomyelitis, Autoimmune, Experimental; HIV Infections; Humans; Immune Tolerance; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Multiple Sclerosis; Neurons; Tryptophan

2007
Metabolism and biology of tryptophan. Some clinical implications.
    Advances in experimental medicine and biology, 1996, Volume: 398

    Topics: Acquired Immunodeficiency Syndrome; Amino Acid Sequence; Animals; Chemotactic Factors; Graft Rejection; Graft vs Host Disease; HIV Infections; HIV-1; Humans; Molecular Sequence Data; Prions; Tryptophan; Viral Proteins

1996
Risk factors for pulmonary arterial hypertension.
    Clinics in chest medicine, 2001, Volume: 22, Issue:3

    Topics: Altitude; Aminorex; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Agents, Second-Generation; Appetite Depressants; Brassica; Comorbidity; Eisenmenger Complex; Fatty Acids, Monounsaturated; Female; Fenfluramine; Glycogen Storage Disease; Hematologic Diseases; HIV Infections; Humans; Hypertension, Portal; Hypertension, Pulmonary; Plant Oils; Pregnancy; Pregnancy Complications, Cardiovascular; Rapeseed Oil; Risk Factors; Smoking; Splenectomy; Telangiectasia, Hereditary Hemorrhagic; Thrombosis; Thyroid Diseases; Tryptophan

2001

Trials

4 trial(s) available for tryptophan and HIV Coinfection

ArticleYear
Effect of aprepitant on kynurenine to tryptophan ratio in cART treated and cART naïve adults living with HIV.
    Medicine, 2021, Jun-11, Volume: 100, Issue:23

    Topics: Adult; Anti-HIV Agents; Aprepitant; CD4 Lymphocyte Count; Double-Blind Method; Drug Therapy, Combination; Female; HIV Infections; Humans; Kynurenine; Male; Mood Disorders; Neuroimmunomodulation; Neurokinin-1 Receptor Antagonists; Ritonavir; Treatment Outcome; Tryptophan

2021
HIV inhibits CD4+ T-cell proliferation by inducing indoleamine 2,3-dioxygenase in plasmacytoid dendritic cells.
    Blood, 2007, Apr-15, Volume: 109, Issue:8

    Topics: Antibodies, Monoclonal; CD4 Antigens; CD4-Positive T-Lymphocytes; Cells, Cultured; Coculture Techniques; Dendritic Cells; Female; HIV Envelope Protein gp120; HIV Infections; HIV-1; Humans; Immune Tolerance; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferons; Kynurenine; Lymphocyte Activation; Male; Plasma Cells; Tryptophan

2007
Decreased plasma ratio of tryptophan to competing large neutral amino acids in human immunodeficiency virus type 1 infected subjects: possible implications for development of neuro-psychiatric disorders.
    Journal of neural transmission (Vienna, Austria : 1996), 1996, Volume: 103, Issue:1-2

    Topics: AIDS Dementia Complex; Amino Acids; HIV Infections; HIV Seropositivity; HIV-1; Humans; Serotonin; Tryptophan

1996
Parallel decrease in neurotoxin quinolinic acid and soluble tumor necrosis factor receptor p75 in serum during highly active antiretroviral therapy of HIV type 1 disease.
    AIDS research and human retroviruses, 2000, Sep-01, Volume: 16, Issue:13

    Topics: Adult; Aged; Aged, 80 and over; Anti-HIV Agents; Antigens, CD; Drug Therapy, Combination; Female; HIV Infections; HIV-1; Humans; Kynurenine; Male; Middle Aged; Quinolinic Acid; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Type II; Reverse Transcriptase Inhibitors; RNA, Viral; Treatment Outcome; Tryptophan; Viral Load

2000

Other Studies

74 other study(ies) available for tryptophan and HIV Coinfection

ArticleYear
Age-Associated Gut Dysbiosis, Marked by Loss of Butyrogenic Potential, Correlates With Altered Plasma Tryptophan Metabolites in Older People Living With HIV.
    Journal of acquired immune deficiency syndromes (1999), 2022, 02-01, Volume: 89, Issue:Suppl 1

    Topics: Aged; Cross-Sectional Studies; Dysbiosis; HIV Infections; Humans; Kynurenine; Middle Aged; Pilot Projects; Tandem Mass Spectrometry; Tryptophan

2022
A Conserved Tryptophan in the Envelope Cytoplasmic Tail Regulates HIV-1 Assembly and Spread.
    Viruses, 2022, 01-12, Volume: 14, Issue:1

    Topics: CD4-Positive T-Lymphocytes; Cell Membrane; env Gene Products, Human Immunodeficiency Virus; HEK293 Cells; HeLa Cells; HIV Envelope Protein gp41; HIV Infections; HIV-1; Humans; T-Lymphocytes; Tryptophan; Virion; Virus Assembly; Virus Internalization; Virus Replication

2022
Association of the Kynurenine Pathway of Tryptophan Metabolism With Human Immunodeficiency Virus-Related Gut Microbiota Alterations and Visceral Adipose Tissue Accumulation.
    The Journal of infectious diseases, 2022, 06-01, Volume: 225, Issue:11

    Topics: Gastrointestinal Microbiome; HIV; HIV Infections; Humans; Intra-Abdominal Fat; Kynurenine; Tryptophan

2022
Kynurenine/tryptophan ratio for detection of active tuberculosis in adults with HIV prior to antiretroviral therapy.
    AIDS (London, England), 2022, 07-15, Volume: 36, Issue:9

    Topics: Adult; Anti-Retroviral Agents; HIV Infections; Humans; Kynurenine; RNA; Tryptophan; Tuberculosis

2022
The IDOze Study: The Link Between Sleep Disruption and Tryptophan-Kynurenine Pathway Activation in Women With Human Immunodeficiency Virus.
    The Journal of infectious diseases, 2022, 10-17, Volume: 226, Issue:8

    Topics: Cross-Sectional Studies; Female; HIV; HIV Infections; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; RNA; Sleep; Tryptophan

2022
Evaluation of characteristic metabolites of aromatic amino acids in patients with HIV infection at different stages of disease.
    Journal of clinical laboratory analysis, 2023, Volume: 37, Issue:1

    Topics: Amino Acids, Aromatic; Biomarkers; HIV Infections; Humans; Metabolic Syndrome; Tandem Mass Spectrometry; Tryptophan

2023
Kynurenic acid blunts A1 astrocyte activation against neurodegeneration in HIV-associated neurocognitive disorders.
    Journal of neuroinflammation, 2023, Mar-30, Volume: 20, Issue:1

    Topics: alpha7 Nicotinic Acetylcholine Receptor; Animals; Astrocytes; HIV; HIV Infections; Kynurenic Acid; Mice; Mice, Transgenic; Neurocognitive Disorders; Tryptophan

2023
Tryptophan metabolism determines outcome in tuberculous meningitis: a targeted metabolomic analysis.
    eLife, 2023, 05-09, Volume: 12

    Topics: Adult; HIV Infections; Humans; Inflammation; Kynurenine; Meningitis, Cryptococcal; Tryptophan; Tuberculosis, Meningeal

2023
Mass Spectrometric Profiling of HLA-B44 Peptidomes Provides Evidence for Tapasin-Mediated Tryptophan Editing.
    Journal of immunology (Baltimore, Md. : 1950), 2023, 11-01, Volume: 211, Issue:9

    Topics: Histocompatibility Antigens Class I; HIV Infections; HLA-B Antigens; HLA-B44 Antigen; Humans; Immunoglobulins; Peptides; Protein Binding; Tryptophan

2023
Abdominal Adipose Tissue Is Associated With Alterations in Tryptophan-Kynurenine Metabolism and Markers of Systemic Inflammation in People With Human Immunodeficiency Virus.
    The Journal of infectious diseases, 2020, 01-14, Volume: 221, Issue:3

    Topics: Abdominal Fat; Aged; Biomarkers; C-Reactive Protein; Cross-Sectional Studies; Female; HIV; HIV Infections; Humans; Inflammation; Kynurenic Acid; Kynurenine; Longitudinal Studies; Male; Middle Aged; Neopterin; Quinolinic Acid; Tryptophan; Waist-Hip Ratio

2020
Why Am I Getting Fat? Exploring Immune-Metabolic Pathways to Central Fat Accumulation in Persons With HIV.
    The Journal of infectious diseases, 2020, 01-14, Volume: 221, Issue:3

    Topics: Abdominal Fat; HIV; HIV Infections; Humans; Inflammation; Kynurenine; Metabolic Networks and Pathways; Tryptophan

2020
Tryptophan Metabolism Activates Aryl Hydrocarbon Receptor-Mediated Pathway To Promote HIV-1 Infection and Reactivation.
    mBio, 2019, 12-17, Volume: 10, Issue:6

    Topics: Antiretroviral Therapy, Highly Active; CD4 Lymphocyte Count; Gene Expression Regulation, Viral; HIV Infections; HIV Long Terminal Repeat; HIV-1; Host-Pathogen Interactions; Humans; Models, Biological; Receptors, Aryl Hydrocarbon; Signal Transduction; tat Gene Products, Human Immunodeficiency Virus; Transcriptional Activation; Tryptophan; Viral Load; Virus Activation

2019
Full-length title: Dramatic HIV DNA degradation associated with spontaneous HIV suppression and disease-free outcome in a young seropositive woman following her infection.
    Scientific reports, 2020, 02-13, Volume: 10, Issue:1

    Topics: APOBEC Deaminases; Codon, Terminator; Cytidine Deaminase; DNA, Viral; Female; Gastrointestinal Microbiome; Genome, Viral; HIV Infections; HIV Seropositivity; HIV-1; Humans; Mutation; Tryptophan; Virus Replication

2020
Tryptophan degradation is associated with risk-taking propensity in methamphetamine users with treated HIV infection.
    Journal of neurovirology, 2020, Volume: 26, Issue:5

    Topics: Adult; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Biotransformation; Cross-Sectional Studies; HIV Infections; Homosexuality, Male; Humans; Impulsive Behavior; Kynurenine; Male; Methamphetamine; Middle Aged; Phenylalanine; Psychological Tests; Risk-Taking; Substance-Related Disorders; Tryptophan; Tyrosine; Viral Load

2020
Diagnostic accuracy of plasma kynurenine/tryptophan ratio, measured by enzyme-linked immunosorbent assay, for pulmonary tuberculosis.
    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2020, Volume: 99

    Topics: Adult; Biomarkers; Enzyme-Linked Immunosorbent Assay; Female; HIV Infections; Humans; Kynurenine; Latent Tuberculosis; Male; Middle Aged; Reproducibility of Results; Sensitivity and Specificity; Tryptophan; Tuberculosis, Pulmonary

2020
Abnormal Levels of Some Biomarkers of Immune Activation Despite Very Early Treatment of Human Immunodeficiency Virus.
    The Journal of infectious diseases, 2021, 05-20, Volume: 223, Issue:9

    Topics: Anti-HIV Agents; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Biomarkers; Chemokine CXCL10; HIV Infections; Humans; Immune System; Interleukin-6; Kynurenine; Lipopolysaccharide Receptors; Male; Receptors, Cell Surface; Receptors, Tumor Necrosis Factor, Type II; Receptors, Urokinase Plasminogen Activator; Tryptophan

2021
Tryptophan depletion predicts lower positive affect in sexual minority men living with HIV who use methamphetamine.
    Journal of neurovirology, 2021, Volume: 27, Issue:1

    Topics: Adult; Affect; Amphetamine-Related Disorders; Central Nervous System Stimulants; HIV Infections; Humans; Longitudinal Studies; Male; Methamphetamine; Middle Aged; Randomized Controlled Trials as Topic; Sexual and Gender Minorities; Tryptophan

2021
Alterations in the Kynurenine Pathway of Tryptophan Metabolism Are Associated With Depression in People Living With HIV.
    Journal of acquired immune deficiency syndromes (1999), 2021, 06-01, Volume: 87, Issue:2

    Topics: Antidepressive Agents; Comorbidity; Depression; Female; HIV Infections; Humans; Kynurenine; Male; Middle Aged; Psychometrics; Quinolinic Acid; Tryptophan

2021
Plasma Kynurenine-to-Tryptophan Ratio, a Highly Sensitive Blood-Based Diagnostic Tool for Tuberculosis in Pregnant Women Living With Human Immunodeficiency Virus (HIV).
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2021, 09-15, Volume: 73, Issue:6

    Topics: Diagnostic Tests, Routine; Female; HIV; HIV Infections; Humans; Kynurenine; Pregnancy; Pregnant Women; Tryptophan; Tuberculosis

2021
Intersecting minority statuses and tryptophan degradation among stimulant-using, sexual minority men living with HIV.
    Journal of consulting and clinical psychology, 2021, Volume: 89, Issue:3

    Topics: Adult; Amphetamine-Related Disorders; Black or African American; Central Nervous System Stimulants; Comorbidity; Ethnicity; Follow-Up Studies; Hispanic or Latino; HIV Infections; Homosexuality, Male; Humans; Longitudinal Studies; Male; Methamphetamine; San Francisco; Sexual and Gender Minorities; Tryptophan

2021
Multivalent Tryptophan- and Tyrosine-Containing [60]Fullerene Hexa-Adducts as Dual HIV and Enterovirus A71 Entry Inhibitors.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2021, Jul-21, Volume: 27, Issue:41

    Topics: Enterovirus; Fullerenes; Hexosaminidase A; HIV Infections; Humans; Tryptophan; Tyrosine

2021
Alcohol Consumption and Tryptophan Metabolism Among People with HIV Prior to Antiretroviral Therapy Initiation: The Uganda ARCH Cohort Study.
    Alcohol and alcoholism (Oxford, Oxfordshire), 2022, Mar-12, Volume: 57, Issue:2

    Topics: Alcohol Drinking; Alcoholism; Cohort Studies; HIV Infections; Humans; Tryptophan; Uganda

2022
Immunologic Pathways That Predict Mortality in HIV-Infected Ugandans Initiating Antiretroviral Therapy.
    The Journal of infectious diseases, 2017, 04-15, Volume: 215, Issue:8

    Topics: Adult; Anti-HIV Agents; Biomarkers; Cohort Studies; Female; Fibrin Fibrinogen Degradation Products; HIV Infections; Humans; Interleukin-6; Kynurenine; Lipopolysaccharide Receptors; Male; Multivariate Analysis; Prognosis; Proportional Hazards Models; T-Lymphocytes; Tryptophan; Uganda; Viral Load

2017
Tryptophan catabolism and immune activation in primary and chronic HIV infection.
    BMC infectious diseases, 2017, 05-16, Volume: 17, Issue:1

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Chronic Disease; Female; HIV Infections; Humans; Kynurenine; Male; Middle Aged; Prospective Studies; Tryptophan

2017
HIV/Human herpesvirus co-infections: Impact on tryptophan-kynurenine pathway and immune reconstitution.
    PloS one, 2017, Volume: 12, Issue:10

    Topics: Adult; Antibodies, Viral; Antiretroviral Therapy, Highly Active; CD4-Positive T-Lymphocytes; Coinfection; Female; Herpes Simplex; Herpesvirus 1, Human; HIV Infections; Humans; Immune Reconstitution Inflammatory Syndrome; Inflammation; Kynurenine; Male; Metabolic Networks and Pathways; Seroepidemiologic Studies; Tryptophan

2017
Plasma Tryptophan-Kynurenine Metabolites Are Altered in Human Immunodeficiency Virus Infection and Associated With Progression of Carotid Artery Atherosclerosis.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2018, 07-02, Volume: 67, Issue:2

    Topics: Adult; Biomarkers; Carotid Arteries; Carotid Artery Diseases; Disease Progression; Female; HIV Infections; Humans; Kynurenine; Male; Middle Aged; Prospective Studies; Tryptophan

2018
Impact of HIV and Type 2 diabetes on Gut Microbiota Diversity, Tryptophan Catabolism and Endothelial Dysfunction.
    Scientific reports, 2018, 04-30, Volume: 8, Issue:1

    Topics: Arginine; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Endothelium; Feces; Female; Gastrointestinal Microbiome; HIV Infections; Humans; Inflammation; Kynurenine; Male; Metabolism; Middle Aged; Neopterin; Risk Factors; RNA, Ribosomal, 16S; Tryptophan

2018
Plasma Indoleamine 2,3-Dioxygenase Activity Is Associated With the Size of the Human Immunodeficiency Virus Reservoir in Patients Receiving Antiretroviral Therapy.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2019, 04-08, Volume: 68, Issue:8

    Topics: Adult; Anti-Retroviral Agents; CD4-CD8 Ratio; CD4-Positive T-Lymphocytes; DNA, Viral; Female; HIV Infections; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Male; Tryptophan; Viral Load

2019
Tryptophan metabolism and its relationship with central nervous system toxicity in people living with HIV switching from efavirenz to dolutegravir.
    Journal of neurovirology, 2019, Volume: 25, Issue:1

    Topics: Adult; Alkynes; Anti-HIV Agents; Antiretroviral Therapy, Highly Active; Benzoxazines; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Central Nervous System; Cyclopropanes; Drug Substitution; Female; Heterocyclic Compounds, 3-Ring; HIV Infections; Humans; Kynurenine; Male; Middle Aged; Oxazines; Piperazines; Prospective Studies; Pyridones; Tryptophan

2019
Activation of the kynurenine pathway is associated with poor outcome in Pneumocystis pneumonia patients infected with HIV: results of 2 months cohort study.
    BMC infectious diseases, 2019, Mar-04, Volume: 19, Issue:1

    Topics: Adult; Antifungal Agents; Area Under Curve; Biomarkers; Chromatography, High Pressure Liquid; Cohort Studies; Female; HIV Infections; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Male; Middle Aged; Pneumocystis; Pneumonia; Prognosis; ROC Curve; Survival Rate; Tandem Mass Spectrometry; Tryptophan

2019
The additive effect of type 2 diabetes on fibrinogen, von Willebrand factor, tryptophan and threonine in people living with HIV.
    Amino acids, 2019, Volume: 51, Issue:5

    Topics: Biomarkers; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Fibrinogen; HIV; HIV Infections; Humans; Male; Middle Aged; Risk Factors; Threonine; Tryptophan; von Willebrand Factor

2019
Elevated indoleamine-2,3-dioxygenase enzyme activity in a novel mouse model of HIV-associated atherosclerosis.
    AIDS (London, England), 2019, 08-01, Volume: 33, Issue:10

    Topics: Animals; Aorta; Aortic Diseases; Atherosclerosis; Cytokines; Diet, High-Fat; Disease Models, Animal; HIV Infections; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Mice, Transgenic; Tryptophan

2019
Two new tryptophan derivatives from the seed kernels of Entada rheedei: effects on cell viability and HIV infectivity.
    Fitoterapia, 2013, Volume: 87

    Topics: Acquired Immunodeficiency Syndrome; Brain; Cell Line; Cell Survival; Dopamine; Fabaceae; Glutamic Acid; HIV; HIV Infections; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Leukocytes, Mononuclear; Melatonin; Molecular Structure; Plant Extracts; Psychotropic Drugs; Seeds; Serotonin; Tryptophan; Virus Replication

2013
A simple LC-MS/MS method for determination of kynurenine and tryptophan concentrations in human plasma from HIV-infected patients.
    Bioanalysis, 2013, Volume: 5, Issue:11

    Topics: Chromatography, Liquid; HIV; HIV Infections; Humans; Kynurenine; Limit of Detection; Tandem Mass Spectrometry; Tryptophan

2013
Dysbiosis of the gut microbiota is associated with HIV disease progression and tryptophan catabolism.
    Science translational medicine, 2013, Jul-10, Volume: 5, Issue:193

    Topics: Animals; Antiretroviral Therapy, Highly Active; Bacteria; Biomarkers; Case-Control Studies; Disease Progression; Dysbiosis; Gastrointestinal Tract; HIV Infections; Humans; Mice; Microbiota; Phylogeny; Tryptophan; Viremia

2013
Distinct tryptophan catabolism and Th17/Treg balance in HIV progressors and elite controllers.
    PloS one, 2013, Volume: 8, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Female; Flow Cytometry; HIV Infections; Humans; Interleukin-6; Lipopolysaccharide Receptors; Male; Middle Aged; T-Lymphocytes, Regulatory; Th17 Cells; Tryptophan; Young Adult

2013
Reversal of the Kynurenine pathway of tryptophan catabolism may improve depression in ART-treated HIV-infected Ugandans.
    Journal of acquired immune deficiency syndromes (1999), 2014, Apr-01, Volume: 65, Issue:4

    Topics: Adult; Antiretroviral Therapy, Highly Active; Depression; Female; HIV Infections; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Male; Metabolic Networks and Pathways; Plasma; Treatment Outcome; Tryptophan; Uganda

2014
The kynurenine pathway of tryptophan catabolism, CD4+ T-cell recovery, and mortality among HIV-infected Ugandans initiating antiretroviral therapy.
    The Journal of infectious diseases, 2014, Aug-01, Volume: 210, Issue:3

    Topics: Adult; Anti-HIV Agents; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Female; HIV Infections; Humans; Kynurenine; Male; Tryptophan; Uganda

2014
Soluble CD40-ligand (sCD40L, sCD154) plays an immunosuppressive role via regulatory T cell expansion in HIV infection.
    Clinical and experimental immunology, 2014, Volume: 178, Issue:1

    Topics: Adult; CD4-Positive T-Lymphocytes; CD40 Ligand; Female; HIV Infections; Humans; Immune Tolerance; Immunosuppressive Agents; Kynurenine; Leukocytes, Mononuclear; Lymphocyte Activation; Male; Middle Aged; T-Lymphocytes, Regulatory; Tryptophan; Young Adult

2014
Anti-retroviral therapy decreases but does not normalize indoleamine 2,3-dioxygenase activity in HIV-infected patients.
    PloS one, 2014, Volume: 9, Issue:7

    Topics: Adult; Anti-Retroviral Agents; CD4 Lymphocyte Count; Female; HIV Infections; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Lipopolysaccharide Receptors; Male; Tryptophan

2014
Immunosuppressive Tryptophan Catabolism and Gut Mucosal Dysfunction Following Early HIV Infection.
    The Journal of infectious diseases, 2015, Aug-01, Volume: 212, Issue:3

    Topics: Adult; Aged; Anti-Retroviral Agents; Biomarkers; Dendritic Cells; HIV Infections; Humans; Intestinal Mucosa; Kynurenine; Longitudinal Studies; Middle Aged; T-Lymphocytes, Regulatory; Tryptophan

2015
The kynurenine pathway activities in a sub-Saharan HIV/AIDS population.
    BMC infectious diseases, 2015, Aug-19, Volume: 15

    Topics: Acquired Immunodeficiency Syndrome; Adult; Africa South of the Sahara; Antiretroviral Therapy, Highly Active; Case-Control Studies; CD4 Lymphocyte Count; Cross-Sectional Studies; Cytokines; Enzyme-Linked Immunosorbent Assay; Female; Flow Cytometry; Gas Chromatography-Mass Spectrometry; HIV Infections; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inflammation; Interferon-gamma; Interleukin-6; Kynurenine; Male; Middle Aged; Neopterin; Niacinamide; Pentosyltransferases; Poverty; Quinolinic Acid; South Africa; Tryptophan

2015
Influence of Hepatitis C Virus Sustained Virological Response on Immunosuppressive Tryptophan Catabolism in ART-Treated HIV/HCV Coinfected Patients.
    Journal of acquired immune deficiency syndromes (1999), 2016, Mar-01, Volume: 71, Issue:3

    Topics: Adult; Anti-HIV Agents; Biomarkers; Coinfection; Disease Progression; Female; Hepacivirus; Hepatitis C; HIV Infections; Humans; Inflammation; Insulin; Kynurenine; Male; Middle Aged; Tryptophan

2016
Increased Tryptophan Catabolism Is Associated With Increased Frequency of CD161+Tc17/MAIT Cells and Lower CD4+ T-Cell Count in HIV-1 Infected Patients on cART After 2 Years of Follow-Up.
    Journal of acquired immune deficiency syndromes (1999), 2015, Nov-01, Volume: 70, Issue:3

    Topics: Adult; Aged; Anti-HIV Agents; CD4 Lymphocyte Count; Drug Administration Schedule; Drug Therapy, Combination; Female; Gene Expression Regulation; HIV Infections; HIV-1; Humans; Interferon-gamma; Kynurenine; Lipopolysaccharide Receptors; Lipopolysaccharides; Male; Middle Aged; T-Lymphocyte Subsets; Transforming Growth Factor beta; Tryptophan

2015
Tryptophan depletion in context of the inflammatory and general nutritional status of a low-income South African HIV-infected population.
    Journal of health, population, and nutrition, 2016, Feb-17, Volume: 35

    Topics: Adult; Antiretroviral Therapy, Highly Active; Biomarkers; Black People; CD4 Lymphocyte Count; Cross-Sectional Studies; Deficiency Diseases; Diet; Female; Food Supply; HIV Infections; Hospitals, Public; Humans; Male; Middle Aged; Neopterin; Nutritional Status; Outpatient Clinics, Hospital; Poverty Areas; South Africa; Suburban Health Services; Tryptophan

2016
Host genetic predictors of the kynurenine pathway of tryptophan catabolism among treated HIV-infected Ugandans.
    AIDS (London, England), 2016, 07-17, Volume: 30, Issue:11

    Topics: Adult; Anti-Retroviral Agents; Female; HIV Infections; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferon-gamma; Kynurenine; Male; Metabolism; Plasma; Risk Assessment; Signal Transduction; Survival Analysis; Toll-Like Receptors; Tryptophan; Tumor Necrosis Factor-alpha; Uganda

2016
HIV-1 Envelope Mimicry of Host Enzyme Kynureninase Does Not Disrupt Tryptophan Metabolism.
    Journal of immunology (Baltimore, Md. : 1950), 2016, 12-15, Volume: 197, Issue:12

    Topics: AIDS Vaccines; Animals; Antibodies, Neutralizing; Cross Reactions; HIV Antibodies; HIV Envelope Protein gp41; HIV Infections; HIV-1; Host-Pathogen Interactions; Humans; Hydrolases; Immune Evasion; Macaca mulatta; Mice; Mice, Inbred C57BL; Mice, Knockout; Molecular Mimicry; Peptides; Tryptophan; Vaccination; Vaccines, Subunit

2016
CD4/CD8 Ratio and KT Ratio Predict Yellow Fever Vaccine Immunogenicity in HIV-Infected Patients.
    PLoS neglected tropical diseases, 2016, Volume: 10, Issue:12

    Topics: Adult; Antibodies, Neutralizing; Antibodies, Viral; CD4-CD8 Ratio; Female; HIV Infections; Humans; Immunogenicity, Vaccine; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Male; Middle Aged; Prospective Studies; Tryptophan; Viremia; Yellow Fever; Yellow Fever Vaccine; Yellow fever virus

2016
Structure-activity relationship studies on a Trp dendrimer with dual activities against HIV and enterovirus A71. Modifications on the amino acid.
    Antiviral research, 2017, Volume: 139

    Topics: Amino Acids; Anti-HIV Agents; Antiviral Agents; Dendrimers; Enterovirus A, Human; Enterovirus Infections; HIV Infections; HIV-1; HIV-2; Humans; Structure-Activity Relationship; Tryptophan; Virus Replication

2017
HIV-induced type I interferon and tryptophan catabolism drive T cell dysfunction despite phenotypic activation.
    PloS one, 2008, Aug-13, Volume: 3, Issue:8

    Topics: ADP-ribosyl Cyclase 1; Antigens, CD; Antigens, Differentiation, T-Lymphocyte; Dendritic Cells; HIV Infections; HIV-1; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferon Type I; Isoantigens; Lectins, C-Type; Lymphocyte Activation; Phenotype; T-Lymphocytes; Tryptophan

2008
Stimulant use is associated with immune activation and depleted tryptophan among HIV-positive persons on anti-retroviral therapy.
    Brain, behavior, and immunity, 2008, Volume: 22, Issue:8

    Topics: Adult; Affective Symptoms; Anti-Retroviral Agents; CD4-Positive T-Lymphocytes; Cocaine; Female; HIV Infections; HIV Seropositivity; Humans; Male; Methamphetamine; Middle Aged; Neopterin; Patient Compliance; Reverse Transcriptase Polymerase Chain Reaction; Tryptophan; Viral Load

2008
The oxidative stress-induced niacin sink (OSINS) model for HIV pathogenesis.
    Toxicology, 2010, Nov-28, Volume: 278, Issue:1

    Topics: HIV Infections; HIV-1; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Models, Biological; Niacin; Oxidative Stress; Poly(ADP-ribose) Polymerases; Selenium; Sulfur; Tryptophan

2010
Insights into therapy: tryptophan oxidation and HIV infection.
    Science translational medicine, 2010, May-19, Volume: 2, Issue:32

    Topics: 3-Hydroxyanthranilic Acid; Anti-Inflammatory Agents; Antiviral Agents; Dendritic Cells; Disease Progression; Enzyme Inhibitors; HIV Infections; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inflammation; Inflammation Mediators; Interleukin-17; Kynurenine; Oxidation-Reduction; T-Lymphocytes, Helper-Inducer; T-Lymphocytes, Regulatory; Tryptophan; Viral Load

2010
Tryptophan catabolism by indoleamine 2,3-dioxygenase 1 alters the balance of TH17 to regulatory T cells in HIV disease.
    Science translational medicine, 2010, May-19, Volume: 2, Issue:32

    Topics: 3-Hydroxyanthranilic Acid; Biopsy; CD4 Lymphocyte Count; CD4-CD8 Ratio; Cells, Cultured; Colon, Sigmoid; Dendritic Cells; Disease Progression; HIV Infections; HIV Seropositivity; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Inflammation; Inflammation Mediators; Interferon-gamma; Interleukin-17; Kynurenine; Lipopolysaccharides; Lymph Nodes; Prospective Studies; Rectum; T-Lymphocytes, Helper-Inducer; T-Lymphocytes, Regulatory; Time Factors; Tryptophan; Up-Regulation; Viral Load

2010
Diversity of HIV-1 subtype B: implications to the origin of BF recombinants.
    PloS one, 2010, Jul-28, Volume: 5, Issue:7

    Topics: env Gene Products, Human Immunodeficiency Virus; HIV Infections; HIV-1; Humans; Phenylalanine; Phylogeny; Tryptophan

2010
Protein adducts as prospective biomarkers of nevirapine toxicity.
    Chemical research in toxicology, 2010, Nov-15, Volume: 23, Issue:11

    Topics: Amino Acid Sequence; Anti-HIV Agents; Biomarkers; Chromatography, High Pressure Liquid; Hemoglobins; HIV Infections; Humans; Mesylates; Molecular Sequence Data; Nevirapine; Reverse Transcriptase Inhibitors; Serum Albumin; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Tryptophan

2010
C868T single nucleotide polymorphism and HIV type 1 disease progression among postpartum women in Kenya.
    AIDS research and human retroviruses, 2012, Volume: 28, Issue:6

    Topics: Adult; Arginine; CD4 Antigens; CD4 Lymphocyte Count; Cohort Studies; Disease Progression; Female; Genotype; HIV Infections; HIV-1; Humans; Infant, Newborn; Kenya; Polymorphism, Single Nucleotide; Postpartum Period; Pregnancy; Tryptophan; Viral Load; Zidovudine

2012
Fatal pancreatitis in simian immunodeficiency virus SIV(mac251)-infected macaques treated with 2',3'-dideoxyinosine and stavudine following cytotoxic-T-lymphocyte-associated antigen 4 and indoleamine 2,3-dioxygenase blockade.
    Journal of virology, 2012, Volume: 86, Issue:1

    Topics: AIDS Vaccines; Animals; Anti-HIV Agents; CTLA-4 Antigen; Didanosine; Disease Models, Animal; Drug Evaluation, Preclinical; Drug Therapy, Combination; HIV Infections; HIV-1; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Macaca mulatta; Pancreatitis; Simian Immunodeficiency Virus; Stavudine; Tryptophan

2012
HIV-1 Tat induces biochemical changes in the serum of mice.
    Virology, 2012, Jan-20, Volume: 422, Issue:2

    Topics: Animals; Discriminant Analysis; Gas Chromatography-Mass Spectrometry; Gene Expression Regulation, Viral; HEK293 Cells; HIV Infections; HIV-1; Humans; Least-Squares Analysis; Male; Mice; Mice, Inbred ICR; Mutation; Principal Component Analysis; Recombinant Proteins; tat Gene Products, Human Immunodeficiency Virus; Transcriptional Activation; Tryptophan

2012
How HIV-1 causes AIDS: implications for prevention and treatment.
    Medical hypotheses, 2004, Volume: 62, Issue:4

    Topics: Acquired Immunodeficiency Syndrome; Cysteine; Glutamine; Glutathione; Glutathione Peroxidase; HIV Infections; HIV Seropositivity; HIV-1; Humans; Nutrition Disorders; Selenium; Tryptophan

2004
Effective antiretroviral therapy reduces degradation of tryptophan in patients with HIV-1 infection.
    Advances in experimental medicine and biology, 2003, Volume: 527

    Topics: Adult; Anti-HIV Agents; Case-Control Studies; Female; HIV Infections; HIV-1; Humans; Immune Tolerance; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferon-gamma; Kynurenine; Male; Middle Aged; Neopterin; T-Lymphocytes; Tryptophan; Tryptophan Oxygenase

2003
Inhibition of indoleamine 2,3-dioxygenase (IDO) enhances elimination of virus-infected macrophages in an animal model of HIV-1 encephalitis.
    Blood, 2005, Oct-01, Volume: 106, Issue:7

    Topics: Animals; Basal Ganglia; Blotting, Western; Brain; CD3 Complex; CD8 Antigens; CD8-Positive T-Lymphocytes; Cell Separation; Disease Models, Animal; Encephalitis, Viral; Flow Cytometry; HIV Infections; Humans; Image Processing, Computer-Assisted; Indoleamine-Pyrrole 2,3,-Dioxygenase; Lymphocytes; Macrophages; Male; Mice; Mice, Inbred NOD; Mice, SCID; Monocytes; T-Lymphocytes, Cytotoxic; Time Factors; Tryptophan; Up-Regulation

2005
A study of tryptophan metabolism via serotonin in ventricular cerebrospinal fluid in HIV-1 infection using a neuroendoscopic technique.
    Current HIV research, 2007, Volume: 5, Issue:2

    Topics: 5-Hydroxytryptophan; Adult; Aged; Cerebral Ventricles; Endoscopy; HIV Infections; HIV-1; Humans; Hydrocephalus; Hydroxyindoleacetic Acid; Male; Melatonin; Serotonin; Tryptophan; Ventriculostomy

2007
Astrocyte indoleamine 2,3-dioxygenase is induced by the TLR3 ligand poly(I:C): mechanism of induction and role in antiviral response.
    Journal of virology, 2007, Volume: 81, Issue:18

    Topics: Astrocytes; Cells, Cultured; Cytokines; Cytomegalovirus; Cytomegalovirus Infections; Encephalitis, Viral; Gene Expression Regulation, Enzymologic; HIV Infections; HIV-1; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferon Inducers; Interferon Regulatory Factor-3; Kynurenine; Ligands; Macrophages; Membrane Glycoproteins; Microglia; NF-kappa B; Nitric Oxide; Oxidoreductases Acting on CH-CH Group Donors; Poly I-C; Proteins; Toll-Like Receptor 3; Tryptophan; Viral Envelope Proteins; Virus Replication

2007
Quality of life and immune activation in patients with HIV-infection.
    Brain, behavior, and immunity, 2008, Volume: 22, Issue:6

    Topics: Acquired Immunodeficiency Syndrome; Adult; CD4 Lymphocyte Count; CD4-Positive T-Lymphocytes; Depression; Disease Progression; Female; Health Status Indicators; Hemoglobins; HIV Infections; Humans; Immunity; Kynurenine; Male; Middle Aged; Neopterin; Predictive Value of Tests; Psychological Tests; Quality of Life; Regression Analysis; Surveys and Questionnaires; Tryptophan; Viral Load

2008
Tryptophan concentrations increase in cerebrospinal fluid and blood after zidovudine treatment in patients with HIV type 1 infection.
    AIDS research and human retroviruses, 1994, Volume: 10, Issue:8

    Topics: Adult; Aged; Biopterins; CD4 Lymphocyte Count; Female; HIV Infections; HIV-1; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Immunoglobulin G; Male; Methoxyhydroxyphenylglycol; Middle Aged; Neopterin; Serotonin; Tryptophan; Zidovudine

1994
HIV infection, serotonin, and sexual dysfunction.
    The British journal of psychiatry : the journal of mental science, 1993, Volume: 162

    Topics: Brain; HIV Infections; Humans; Serotonin; Sexual Dysfunctions, Psychological; Tryptophan

1993
An in vivo mutation from leucine to tryptophan at position 210 in human immunodeficiency virus type 1 reverse transcriptase contributes to high-level resistance to 3'-azido-3'-deoxythymidine.
    Journal of virology, 1996, Volume: 70, Issue:11

    Topics: Base Sequence; Cell Line; Cell Line, Transformed; DNA, Viral; Drug Resistance, Microbial; HIV Infections; HIV Reverse Transcriptase; HIV-1; Humans; Leucine; Models, Molecular; Molecular Sequence Data; Point Mutation; Reverse Transcriptase Inhibitors; Tryptophan; Zidovudine

1996
Increase of tryptophan in serum and in cerebrospinal fluid of patients with HIV infection during zidovudine therapy.
    Advances in experimental medicine and biology, 1996, Volume: 398

    Topics: Anti-HIV Agents; Biopterins; Chromatography, High Pressure Liquid; HIV Infections; HIV Seropositivity; Humans; Kynurenine; Neopterin; Quinolinic Acid; Radioimmunoassay; Time Factors; Tryptophan; Zidovudine

1996
Effect on serologic reactivity of P-to-W substitution in the apex of the V3 loop of the HIV-1 subtype B glycoprotein.
    Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association, 1998, Jan-01, Volume: 17, Issue:1

    Topics: Antibody Specificity; Brazil; Genetic Variation; HIV Antibodies; HIV Envelope Protein gp120; HIV Infections; HIV-1; Peptide Fragments; Proline; Tryptophan

1998
A 100-amino acid truncation in the cytoplasmic tail of glycoprotein 41 in the reference HIV type 1 strain RF.
    AIDS research and human retroviruses, 2002, May-01, Volume: 18, Issue:7

    Topics: Amino Acid Sequence; Base Sequence; DNA, Viral; Gene Deletion; Giant Cells; HIV Envelope Protein gp41; HIV Infections; HIV-1; Humans; Molecular Sequence Data; Molecular Weight; Monocytes; Point Mutation; Tryptophan; Tumor Cells, Cultured

2002
Nocturnal sleep EEG in patients with HIV infection.
    European archives of psychiatry and clinical neuroscience, 1991, Volume: 240, Issue:3

    Topics: Adult; AIDS Dementia Complex; Arousal; Circadian Rhythm; Electroencephalography; Female; HIV Infections; HIV Seropositivity; Humans; Male; Middle Aged; Serotonin; Sleep Stages; Tryptophan

1991
Increased endogenous interferon-gamma and neopterin correlate with increased degradation of tryptophan in human immunodeficiency virus type 1 infection.
    Immunology letters, 1991, Volume: 28, Issue:3

    Topics: Adult; Biopterins; Chromatography, High Pressure Liquid; Female; HIV Infections; HIV Seropositivity; HIV-1; Humans; Interferon-gamma; Kynurenine; Male; Middle Aged; Neopterin; Radioimmunoassay; Tryptophan

1991
Immune activation and decreased tryptophan in patients with HIV-1 infection.
    Journal of interferon research, 1990, Volume: 10, Issue:6

    Topics: Adult; Biopterins; Enzyme Induction; HIV Infections; HIV-1; Humans; Interferon-gamma; Middle Aged; Neopterin; Tryptophan; Tryptophan Oxygenase

1990