tryptophan and Glioma

tryptophan has been researched along with Glioma in 34 studies

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-19903 (8.82)18.7374
1990's2 (5.88)18.2507
2000's3 (8.82)29.6817
2010's18 (52.94)24.3611
2020's8 (23.53)2.80

Authors

AuthorsStudies
Acharya, R; Bao, R; Bell, A; Bollu, L; Chen, P; Clark, SJ; Genet, M; Griffiths, J; Horbinski, C; Kim, M; Ladomersky, E; Lauing, KL; Lukas, RV; Mi, X; Nguyen, B; Schiltz, GE; Schipma, MJ; Unwin, RD; Wainwright, DA; Wray, B; Wu, JD; Zhai, L1
Chen, Q; Geng, R; Liu, B; Sun, Q; Xu, Y; Yuan, F; Zhang, H1
Cote, DJ; Egan, KM; McCann, A; Midttun, Ø; Samanic, CM; Smith-Warner, SA; Stampfer, MJ; Ueland, PM; Wang, M; Yue, Y1
Abu-Sammour, D; Aslan, K; Beck, J; Böttcher, C; Bunse, L; Bunse, T; Cichon, F; Fernandez-Zapata, C; Friedrich, M; Gegner, HM; Green, E; Gutcher, I; Hahn, M; Heiland, DH; Heiland, S; Hopf, C; Kessler, T; Kilian, M; Münch, P; Platten, M; Poschet, G; Priller, J; Prinz, M; Pusch, S; Quintana, FJ; Ramallo Guevara, C; Ratliff, M; Sahm, F; Sanghvi, K; Sankowski, R; Schirmer, L; Schnell, O; Schrimpf, D; Sonner, JK; Trobisch, T; von Deimling, A; von Landenberg, A; Wick, W1
Obara-Michlewska, M1
Jiang, S; Li, J; Lv, L; Ma, W; Ye, F; Ye, L; Yu, Y; Zhong, C; Zhou, P1
Huntosova, V; Kozar, T; Stroffekova, K; Tomkova, S1
Alfano, RR; Cheng, G; Liu, CH; Shi, L; Wang, K; Wu, B; Yu, X; Zhang, C; Zhang, L; Zhao, M; Zhou, Y; Zhu, K; Zong, R1
Alekar, S; Cloughesy, T; Desjardins, A; Lassman, AB; Li, R; Reardon, DA; Rixe, O; Taylor, CT; Williams, JH1
Friedrich, M; Opitz, CA; Panitz, V; Platten, M; Wainwright, DA1
Ali-Fehmi, R; Fadel, HA; Guastella, AR; Juhász, C; Kiousis, S; Klinger, NV; Kupsky, WJ; Michelhaugh, SK; Mittal, S1
Adams, S; Ahrendt, T; Bode, HB; Guillemin, GJ; Oezen, I; Opitz, CA; Platten, M; Radlwimmer, B; Sahm, F; von Deimling, A; Wick, W1
Barger, GR; Juhász, C; Kamson, DO; Kupsky, WJ; Mittal, S; Muzik, O; Robinette, NL1
Platten, M; Weller, M; Wick, W1
Barger, GR; Chakraborty, PK; Juhász, C; Kamson, DO; Lee, TJ; Mittal, S; Muzik, O; Robinette, NL; Snyder, M; Varadarajan, K1
Adams, S; Braidy, N; Brew, BJ; Bustamante, S; Guillemin, GJ; Lim, CK; McDonald, KL; Sundaram, G; Teo, C; Zinger, A1
Bosnyák, E; Guastella, AR; Juhász, C; Kamson, DO; Kupsky, WJ; Michelhaugh, SK; Mittal, S; Muzik, O; Robinette, NL; Varadarajan, K1
Barger, GR; Bosnyák, E; Chugani, DC; Jeong, JW; Juhász, C; Kamson, DO; Kupsky, WJ; Mittal, S; Robinette, NL1
Hanihara, M; Kawataki, T; Kinouchi, H; Mitsuka, K; Nakao, A; Oh-Oka, K1
Anderson, G; Beischlag, TV; Mazzoccoli, G1
Akiyama, Y; Hara, N; Miyazaki, T; Moritake, K; Osago, H; Shibata, T; Tsuchiya, M; Yamada, K1
Barger, GR; Chakraborty, PK; Chugani, DC; Chugani, HT; Juhász, C; Mittal, S; Muzik, O; Sood, S1
Almeida, JR; Almeida, LO; Casartelli, C; Clara, CA; Custódio, AC; Pinto, GR; Rey, JA; Santos, MJ1
Guillemin, GJ; Jestaedt, L; Jugold, M; Lehmann, I; Litzenburger, UM; Lutz, C; Miller, CL; Opitz, CA; Ott, M; Platten, M; Radlwimmer, B; Sahm, F; Schrenk, D; Schumacher, T; Tritschler, I; Trump, S; von Deimling, A; Weller, M; Wick, W1
Alkonyi, B; Bahl, G; Barger, GR; Chakraborty, PK; Chugani, DC; Juhász, C; Kupsky, WJ; Mittal, S; Muzik, O; Robinette, NL1
Barger, GR; Chakraborty, PK; Chugani, DC; Juhász, C; Kupsky, WJ; Mittal, S; Muzik, O1
Barger, GR; Buth, A; Chakraborty, PK; Juhász, C; Kamson, DO; Kupsky, WJ; Mittal, S; Muzik, O1
Gibbs, WD; Hübner, KF; King, P; Mahaley, SM; Partain, CL; Purvis, JT; Robertson, JT; Rogers, S1
Bilzer, T; Däubener, W; Fischer, HG; Hadding, U; Pilz, K; Seghrouchni Zennati, S1
Boado, RJ; Li, JY; Nagaya, M; Pardridge, WM; Zhang, C1
Arun, P; Deepadevi, KV; Kurup, PA; Manojkumar, V; Ravikumar, A1
Arun, P; Devi, KV; Kurup, PA; Ravikumar, A1
Furuya, S; Higashida, H; Nagatsu, T; Sawada, M; Suzuki, O1
Abdullakhozhaeva, MS; Dimant, IN; Faĭn, NG1

Reviews

5 review(s) available for tryptophan and Glioma

ArticleYear
Immunomodulatory Effects of Tryptophan Metabolism in the Glioma Tumor Microenvironment.
    Frontiers in immunology, 2021, Volume: 12

    Topics: Animals; Brain Neoplasms; Cell Differentiation; Glioma; Humans; Immune Checkpoint Inhibitors; Immunotherapy; Lymphocytes, Tumor-Infiltrating; T-Lymphocytes, Regulatory; Tryptophan; Tumor Microenvironment

2021
The tryptophan metabolism, kynurenine pathway and oxidative stress - implications for glioma pathobiology.
    Neurochemistry international, 2022, Volume: 158

    Topics: Brain Neoplasms; Glioma; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Oxidative Stress; Tryptophan

2022
Tryptophan metabolism in brain tumors - IDO and beyond.
    Current opinion in immunology, 2021, Volume: 70

    Topics: Brain Neoplasms; Glioma; Humans; Immunotherapy; Indoleamine-Pyrrole 2,3,-Dioxygenase; Tryptophan; Tumor Microenvironment

2021
Shaping the glioma immune microenvironment through tryptophan metabolism.
    CNS oncology, 2012, Volume: 1, Issue:1

    Topics: Animals; Central Nervous System Neoplasms; Glioma; Humans; Tryptophan

2012
Glioma: Tryptophan Catabolite and Melatoninergic Pathways Link microRNA, 14-3- 3, Chromosome 4q35, Epigenetic Processes and other Glioma Biochemical Changes.
    Current pharmaceutical design, 2016, Volume: 22, Issue:8

    Topics: Animals; Chromosomes, Human, Pair 4; Epigenesis, Genetic; Glioma; Humans; Inflammation; Melatonin; MicroRNAs; Oxidative Stress; Tryptophan

2016

Trials

2 trial(s) available for tryptophan and Glioma

ArticleYear
A phase 1 study of PF-06840003, an oral indoleamine 2,3-dioxygenase 1 (IDO1) inhibitor in patients with recurrent malignant glioma.
    Investigational new drugs, 2020, Volume: 38, Issue:6

    Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Central Nervous System Neoplasms; Female; Glioma; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Indoles; Kynurenine; Male; Middle Aged; Neoplasm Recurrence, Local; Succinimides; Treatment Outcome; Tryptophan; Young Adult

2020
Quantitative PET imaging of tryptophan accumulation in gliomas and remote cortex: correlation with tumor proliferative activity.
    Clinical nuclear medicine, 2012, Volume: 37, Issue:9

    Topics: Adult; Aged; Biological Transport; Brain Neoplasms; Case-Control Studies; Cell Proliferation; Cerebral Cortex; Female; Glioma; Humans; Ki-67 Antigen; Kinetics; Male; Middle Aged; Positron-Emission Tomography; Tryptophan; Young Adult

2012

Other Studies

27 other study(ies) available for tryptophan and Glioma

ArticleYear
Tumor Cell IDO Enhances Immune Suppression and Decreases Survival Independent of Tryptophan Metabolism in Glioblastoma.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2021, 12-01, Volume: 27, Issue:23

    Topics: Animals; Glioblastoma; Glioma; Humans; Immunosuppression Therapy; Indoleamine-Pyrrole 2,3,-Dioxygenase; Mice; Tryptophan

2021
A prospective study of pre-diagnostic circulating tryptophan and kynurenine, and the kynurenine/tryptophan ratio and risk of glioma.
    Cancer epidemiology, 2022, Volume: 76

    Topics: Case-Control Studies; Follow-Up Studies; Glioma; Humans; Kynurenine; Prospective Studies; Tryptophan; Tumor Microenvironment

2022
Tryptophan metabolism drives dynamic immunosuppressive myeloid states in IDH-mutant gliomas.
    Nature cancer, 2021, Volume: 2, Issue:7

    Topics: Brain Neoplasms; Glioma; Humans; Immunotherapy; Isocitrate Dehydrogenase; Tryptophan; Tumor Microenvironment

2021
Kynurenine produced by tryptophan 2,3-dioxygenase metabolism promotes glioma progression through an aryl hydrocarbon receptor-dependent signaling pathway.
    Cell biology international, 2022, Volume: 46, Issue:10

    Topics: Animals; Dioxygenases; Glioma; Kynurenine; Mice; Phosphatidylinositol 3-Kinases; Receptors, Aryl Hydrocarbon; Signal Transduction; Tryptophan; Tryptophan Oxygenase

2022
Importance of Hypericin-Bcl2 interactions for biological effects at subcellular levels.
    Photodiagnosis and photodynamic therapy, 2019, Volume: 28

    Topics: Aniline Compounds; Anthracenes; Cell Line, Tumor; Cell Survival; Fluorescence; Glioma; Humans; Molecular Docking Simulation; Molecular Structure; Perylene; Photochemotherapy; Photosensitizing Agents; Proto-Oncogene Proteins c-bcl-2; Sulfonamides; Tryptophan; Tyrosine

2019
Optical biopsy identification and grading of gliomas using label-free visible resonance Raman spectroscopy.
    Journal of biomedical optics, 2019, Volume: 24, Issue:9

    Topics: Biomarkers, Tumor; Brain; Brain Neoplasms; Carotenoids; Glioma; Humans; Lipid Metabolism; Margins of Excision; Neoplasm Grading; Nerve Tissue Proteins; Optical Phenomena; Principal Component Analysis; Protein Structure, Secondary; Spectrum Analysis, Raman; Support Vector Machine; Tryptophan

2019
Investigation of the aryl hydrocarbon receptor and the intrinsic tumoral component of the kynurenine pathway of tryptophan metabolism in primary brain tumors.
    Journal of neuro-oncology, 2018, Volume: 139, Issue:2

    Topics: Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Glioma; Humans; Kynurenine; Meningeal Neoplasms; Meningioma; Neoplasm Grading; Receptors, Aryl Hydrocarbon; Tryptophan

2018
The endogenous tryptophan metabolite and NAD+ precursor quinolinic acid confers resistance of gliomas to oxidative stress.
    Cancer research, 2013, Jun-01, Volume: 73, Issue:11

    Topics: Antineoplastic Agents, Alkylating; Apoptosis; Cell Line, Tumor; Dacarbazine; Drug Resistance, Neoplasm; Glioma; Humans; Microglia; NAD; Oxidative Stress; Pentosyltransferases; Quinolinic Acid; Temozolomide; Tryptophan; Tryptophan Oxygenase

2013
Increased tryptophan uptake on PET has strong independent prognostic value in patients with a previously treated high-grade glioma.
    Neuro-oncology, 2014, Volume: 16, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Brain Neoplasms; Carbon Radioisotopes; Female; Glioma; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Positron-Emission Tomography; Prognosis; Survival Analysis; Tryptophan

2014
Clinical significance of tryptophan metabolism in the nontumoral hemisphere in patients with malignant glioma.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2014, Volume: 55, Issue:10

    Topics: Adult; Aged; Brain; Brain Neoplasms; Female; Glioma; Humans; Kynurenine; Magnetic Resonance Imaging; Male; Middle Aged; Positron-Emission Tomography; Prognosis; Proportional Hazards Models; Serotonin; Tryptophan

2014
Involvement of the kynurenine pathway in human glioma pathophysiology.
    PloS one, 2014, Volume: 9, Issue:11

    Topics: Antigens, CD; Antigens, Differentiation, Myelomonocytic; Astrocytes; Biosynthetic Pathways; Brain Neoplasms; Carboxy-Lyases; CD11b Antigen; Cells, Cultured; Chromatography, High Pressure Liquid; Disaccharides; Gene Expression; Glial Fibrillary Acidic Protein; Glioma; Glucuronates; Humans; Immunohistochemistry; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferon-gamma; Kynurenic Acid; Kynurenine; Picolinic Acids; Quinolinic Acid; Reverse Transcriptase Polymerase Chain Reaction; Tryptophan; Tryptophan Oxygenase; Tumor Cells, Cultured

2014
Molecular imaging correlates of tryptophan metabolism via the kynurenine pathway in human meningiomas.
    Neuro-oncology, 2015, Volume: 17, Issue:9

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Brain; Child; Female; Glioma; Humans; Kynurenine; Male; Meningeal Neoplasms; Meningioma; Middle Aged; Neoplasm Grading; Positron-Emission Tomography; Signal Transduction; Tryptophan; Young Adult

2015
Multi-modal imaging of tumor cellularity and Tryptophan metabolism in human Gliomas.
    Cancer imaging : the official publication of the International Cancer Imaging Society, 2015, Aug-06, Volume: 15

    Topics: Adolescent; Adult; Aged; Brain Neoplasms; Cellulase; Diffusion Tensor Imaging; Female; Glioma; Humans; Immunohistochemistry; Male; Positron-Emission Tomography; ROC Curve; Tryptophan

2015
Synergistic antitumor effect with indoleamine 2,3-dioxygenase inhibition and temozolomide in a murine glioma model.
    Journal of neurosurgery, 2016, Volume: 124, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Cell Line, Tumor; Dacarbazine; Drug Synergism; Enzyme Inhibitors; Female; Gene Knockdown Techniques; Glioma; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Neoplasm Transplantation; RNA, Messenger; Survival Analysis; Temozolomide; Treatment Outcome; Tryptophan; Tumor Burden

2016
Indoleamine 2,3-dioxygenase as a new target for malignant glioma therapy. Laboratory investigation.
    Journal of neurosurgery, 2009, Volume: 111, Issue:2

    Topics: Antineoplastic Agents; Drug Delivery Systems; Glioma; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferon-gamma; Tryptophan; Tumor Cells, Cultured

2009
Differential kinetics of α-[¹¹C]methyl-L-tryptophan on PET in low-grade brain tumors.
    Journal of neuro-oncology, 2011, Volume: 102, Issue:3

    Topics: Adolescent; Adult; Analysis of Variance; Brain Mapping; Brain Neoplasms; Carbon Radioisotopes; Child; Child, Preschool; Female; Glioma; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Positron-Emission Tomography; Tryptophan

2011
Analysis of the polymorphisms XRCC1Arg194Trp and XRCC1Arg399Gln in gliomas.
    Genetics and molecular research : GMR, 2011, Jun-14, Volume: 10, Issue:2

    Topics: Arginine; Brain Neoplasms; DNA Primers; DNA-Binding Proteins; Glioma; Glycine; Humans; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Tryptophan; X-ray Repair Cross Complementing Protein 1

2011
An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor.
    Nature, 2011, Oct-05, Volume: 478, Issue:7368

    Topics: Animals; Autocrine Communication; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Disease Progression; Gene Expression Regulation, Neoplastic; Glioma; Humans; Kynurenine; Ligands; Mice; Mice, Inbred C57BL; Mice, Nude; Neoplasm Transplantation; Paracrine Communication; Receptors, Aryl Hydrocarbon; Tryptophan; Tryptophan Oxygenase

2011
Accurate differentiation of recurrent gliomas from radiation injury by kinetic analysis of α-11C-methyl-L-tryptophan PET.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2012, Volume: 53, Issue:7

    Topics: Adult; Aged; Brain Neoplasms; Diagnosis, Differential; Female; Fluorodeoxyglucose F18; Glioma; Humans; Image Processing, Computer-Assisted; Ki-67 Antigen; Male; Middle Aged; Neoplasm Recurrence, Local; Radiation Injuries; Radionuclide Imaging; Radiopharmaceuticals; Reference Standards; Reproducibility of Results; ROC Curve; Tryptophan

2012
Tryptophan PET in pretreatment delineation of newly-diagnosed gliomas: MRI and histopathologic correlates.
    Journal of neuro-oncology, 2013, Volume: 112, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Brain; Brain Neoplasms; Carbon Isotopes; Female; Gadolinium; Glioma; Humans; Imaging, Three-Dimensional; Magnetic Resonance Imaging; Male; Middle Aged; Positron-Emission Tomography; Statistics, Nonparametric; Tryptophan; Young Adult

2013
Brain tumor imaging by positron emission computed tomography using 11C-labeled amino acids.
    Journal of computer assisted tomography, 1982, Volume: 6, Issue:3

    Topics: Adult; Aged; Amino Acids; Astrocytoma; Brain Neoplasms; Carbon Radioisotopes; Ependymoma; Female; Glioblastoma; Glioma; Humans; Male; Meningioma; Middle Aged; Tomography, Emission-Computed; Tryptophan; Valine

1982
Induction of toxoplasmostasis in a human glioblastoma by interferon gamma.
    Journal of neuroimmunology, 1993, Volume: 43, Issue:1-2

    Topics: Animals; Astrocytes; Glioma; Humans; Interferon-gamma; Monocytes; Superoxides; Toxoplasma; Tryptophan; Tryptophan Oxygenase; Tumor Cells, Cultured

1993
Selective expression of the large neutral amino acid transporter at the blood-brain barrier.
    Proceedings of the National Academy of Sciences of the United States of America, 1999, Oct-12, Volume: 96, Issue:21

    Topics: Amino Acid Sequence; Amino Acid Transport Systems; Animals; Base Sequence; Blood-Brain Barrier; Blotting, Northern; Brain; Carrier Proteins; Cattle; Dose-Response Relationship, Drug; Gene Library; Glioma; Kinetics; Molecular Sequence Data; Rats; Transcription, Genetic; Tryptophan; Tumor Cells, Cultured; Xenopus

1999
Tryptophan and tyrosine catabolic pattern in neuropsychiatric disorders.
    Neurology India, 2000, Volume: 48, Issue:3

    Topics: Adult; Biogenic Monoamines; Brain Diseases; Brain Neoplasms; Digoxin; Epilepsy, Generalized; Erythrocytes; Fatty Acids, Nonesterified; Female; Glioma; Glycine Agents; Humans; Hydroxymethylglutaryl CoA Reductases; Kynurenic Acid; Magnesium; Male; Microvascular Angina; Middle Aged; Morphine; Narcotics; Nicotine; Nicotinic Agonists; Parkinson Disease; Quinolinic Acid; Schizophrenia; Serum Albumin; Sodium-Potassium-Exchanging ATPase; Strychnine; Tryptophan; Tyrosine; Ubiquinone

2000
Endogenous strychnine, nicotine, and morphine--description of hypo and hyper-strychninergic, nicotinergic and morphinergic state in relation to neuropsychiatric diseases.
    Indian journal of experimental biology, 2000, Volume: 38, Issue:6

    Topics: Adult; Alkaloids; Brain Neoplasms; Chromatography, High Pressure Liquid; Erythrocyte Membrane; Glioma; Humans; Male; Mental Disorders; Middle Aged; Morphine; Neoplasm Proteins; Nervous System Diseases; Nicotine; Sodium-Potassium-Exchanging ATPase; Strychnine; Tryptophan; Tyrosine

2000
Localization of [3H]serotonin in neuroblastoma x glioma hybrid cells.
    Brain research, 1985, Dec-30, Volume: 361, Issue:1-2

    Topics: Animals; Autoradiography; Biological Transport; Cell Line; Glioma; Hybrid Cells; Kinetics; Mice; Microscopy, Electron; Neuroblastoma; Rats; Serotonin; Tritium; Tryptophan; Tryptophan Hydroxylase

1985
[Data towards the histochemical characteristics of brain tumors in rats].
    Arkhiv patologii, 1966, Volume: 28, Issue:5

    Topics: Animals; Arachnoid; Astrocytoma; Brain Neoplasms; DNA; Ependymoma; Glioblastoma; Glioma; Hemangioendothelioma; Histidine; Neoplasms, Experimental; Oligodendroglioma; Protein Biosynthesis; Rats; RNA; Tryptophan; Tyrosine

1966