Compounds > tryptophan

tryptophan and Genetic Predisposition

tryptophan has been researched along with Genetic Predisposition in 100 studies

Research

Studies (100)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's7 (7.00)18.2507
2000's54 (54.00)29.6817
2010's36 (36.00)24.3611
2020's3 (3.00)2.80

Authors

AuthorsStudies
Darville, T; Hillier, SL; Kollipara, A; Li, Y; Liu, Y; O'Connell, CM; Poston, TB; Wang, Y; Wiesenfeld, HC; Yount, K; Zheng, X; Zhong, W1
Baid-Agrawal, S; Boerwinkle, E; Coresh, J; Eckardt, KU; Grams, ME; Kӧttgen, A; Luo, S; Mohney, RP; Schultheiss, UT; Sekula, P; Steinbrenner, I; Tin, A; Yu, B1
Bravo, R; Castaño, MY; Kirsch, P; Plieger, T; Reuter, M; Rodríguez, AB; Ugartemendia, L; Zamoscik, V1
Lamas, B; Richard, ML; Sokol, H1
Chen, X; Fu, X; Luo, J; Peng, X; Wang, L; Wang, X; Xiao, Z; Zhou, JX; Zhu, B1
Chen, QY; Fu, DJ; Li, J; Liu, ZM; Mao, TT; Peng, YJ; She, WT1
Achmad, TH; Aguirre-Gamboa, R; Alisjahbana, B; Annisa, J; Avila-Pacheco, J; Chaidir, L; Clish, CB; Dian, S; Ganiem, AR; Joosten, LAB; Koeken, VACM; Kumar, V; Li, Y; Netea, MG; Notebaart, RA; Ricaño-Ponce, I; Ruesen, C; Ruslami, R; van Crevel, R; van Laarhoven, A; Verbeek, MM1
Bănescu, C; Dobreanu, M; Duicu, C; Trifa, AP1
Anderson, G; Berk, M; Kubera, M; Maes, M1
Anbarasu, A; Kumar, CV; Ramaiah, S; Swetha, RG1
Ciorba, MA; Kanuri, N; Lee, A; Li, E; Sayuk, GS; Zhang, Y1
Banerjee, E; Nandagopal, K1
Aan Het Rot, M; Hogenelst, K; Schoevers, RA1
Glick, AR1
Johannsen, S; Mögele, S; Müller, CR; Roewer, N; Schneiderbanger, D; Schuster, F; Treves, S1
Abdi, M; Amini, S; Ghaderi, B; Jalali, C; Roshani, D1
Cordell, H; Donaldson, P; Fichna, M; Fichna, P; Gryczyńska, M; Januszkiewicz-Lewandowska, D; McDonald, D; Nowak, J; Owen, K; Pearce, S; Roycroft, M; Zurawek, M1
Charney, DS; Drevets, WC; Goldman, D; Herscovitch, P; Neumeister, A; Nugent, AC1
Allen, JJ; Delgado, PL; Demaree, HA; McKnight, KM; Moreno, FA1
Abramson, RK; Anderson, BM; Bartlett, J; Cuccaro, ML; Gilbert, JR; Haines, JL; Pericak-Vance, MA; Schnetz-Boutaud, NC; Wotawa, AM; Wright, HH1
Barton, KA; Bhagyalaxmi, SG; Bhanuprakash Reddy, G; Kumar, KR; Padma, T; Petrash, JM; Srinivas, P; Vidyavathi, M1
Derakhshandeh, S; Farrashbandi, H; Saadat, I; Saadat, M1
Pinheiro, TJ; Robinson, PJ1
Donglan, S; Na, W; Rongmiao, Z; Yan, L; Yanan, D; Zhifeng, C1
Feng, X; Jiang, L; Li, J; Wang, Z; Zeng, X; Zhang, Y; Zhou, C; Zhou, Y1
Kamb, ML; Love, LA; Miller, FW; Okada, S; Pandey, JP; Philen, RM1
Karlsson, A; Larsson, NG; Lesko, N; Naess, K; Nennesmo, I; Solaroli, N; von Döbeln, U; Wibom, R1
Chistiakov, DA; Kuraeva, TL; Lavrikova, EY; Nikitin, AG; Nosikov, VV; Peterkova, VA; Tsitlidze, NM1
Bi, L; Chen, W; Guo, L; Qi, H; Qian, Y; Tao, T; Wang, Y; Wu, J; Xu, W1
Oxenkrug, GF1
Brennan, SO; Davis, RL1
Kulikov, AV; Popova, NK1
Bihoreau, MT; Gretz, N; Hoffmann, SC; Kränzlin, B; Maier, E; Menon, K; Neudecker, S; Obermüller, N; Walz, R1
Gu, W; Huang, Y; Liu, J; Liu, K; Liu, Y; Lou, Y; Niu, Q; Wang, Z; Wen, S; Zhu, X1
Hsiao, HH; Hsu, JF; Lee, CP; Lin, SF; Liu, YC; Tsai, HJ1
Eyre, DR; Mirza, SK; Weis, MA; Wu, JJ; Zhu, Y1
Bernardo, A; Capsoni, S; Cattaneo, A; Ceci, M; Covaceuszach, S; Marinelli, S; Minghetti, L; Pavone, F; Ugolini, G1
Pendyala, L; Superko, R; Williams, P1
Bradley, DT; Hughes, AE; Mullan, GM1
Hoshi, M; Ito, H; Kanamori, H; Moriwaki, H; Nagaki, M; Ohtaki, H; Osawa, Y; Saito, K; Seishima, M; Seki, E; Suetsugu, A; Yasuda, Y1
Dabelic, S; Dumic, J; Goreta, SS; Lauc, G; Pavlinic, D1
Bhowmik, AD; Chaudhuri, K; Mukherjee, S; Mukhopadhyay, K; Ray, JG; Roychoudhury, P1
Fisher, D; Ilivitsky, V; Jaworska, N; Knott, V; Shah, D; Thompson, A1
Ghanizadeh, A; Mohammadynejad, P; Saadat, I; Saadat, M1
Berciano, J; Infante, J; Pelayo-Negro, AL; Rodríguez-Oroz, MC; Sánchez-Quintana, C; Tola-Arribas, MA; Volpini, V; Zeviani, M1
Cavalli, IJ; de Oliveira, BV; de Souza Fonseca Ribeiro, EM; de Syllos Cólus, IM; Dos Reis, MB; Losi-Guembarovski, R; Mizuno, LT; Morita, MC; Ramos, GH; Rogatto, SR1
Camargo, SM; Clevers, H; Fukamizu, A; Hanada, R; Hanada, T; Hashimoto, T; Ishiguro, H; Kuba, K; Lipinski, S; Paolino, M; Penninger, JM; Perlot, T; Rehman, A; Richter, A; Rosenstiel, P; Schreiber, S; Sigl, V; Singer, D; Trichereau, J; Verrey, F; Wild, B1
Li, SW; Li, Y; Liu, F; Tan, SQ; Wang, Y1
Boonsuwan, T; Kitkumthorn, N; Mutirangura, A; Yanatatsaneejit, P1
Komiya, I; Shimabukuro, M; Shimajiri, Y; Takasu, N; Tomoyose, T; Yogi, H1
Ammar, N; Amouri, R; Barisić, N; Ceuterick, C; De Jonghe, P; Hentati, F; Martin, JJ; Merlini, L; Nelis, E; Timmerman, V1
Christophe, A; De Vriese, SA; Helsdingen, RW; Honig, A; Maes, M; Riedel, WJ; Sobczak, S1
Chatzis, C; Christiani, DC; Halla, M; Kales, SN; Linos, A; Nasioulas, G; Sai, Y1
Bellabarba, C; Carter, B; Chapman, JR; Eyre, DR; Matsui, Y; Mirza, SK; Shaffrey, CI; Wu, JJ1
Cao, WH; Guo, XX; Hu, YH; Li, LM; Li, QN; Lv, J; Qin, Y; Zhan, SY1
Heliö, T; Jääskeläinen, P; Kaartinen, M; Kärkkäinen, S; Kuusisto, J; Laakso, M; Miettinen, R; Nieminen, MS; Peuhkurinen, K; Reissell, E; Toivonen, L; Tuomainen, P; Ylitalo, K1
Fisher, SA; Grumley, JA; Kingsley, GH; Lad, B; Steer, S1
Bamezai, R; Malhotra, D; Reddy, BS; Relhan, V1
Kuzuya, N1
Austin, MA; Edwards, KL; Williams, MA; Zhang, C1
Aschauer, HN; Basile, VS; Cavallaro, R; Chong, SA; Heresco-Levy, U; Kennedy, JL; Lerer, B; Macciardi, F; Meltzer, HY; Scharfetter, J; Segman, RH; Strous, R; Tan, EC; Verga, M1
Csernus, K; Czakó, M; Erhardt, E; Kosztolányi, G; Molnár, D1
Bresso, F; D'Amato, M; Halfvarson, J; Järnerot, G; Pettersson, S; Tysk, C1
Akhtar, S; Blomhoff, A; Cantón, I; Gavalas, NG; Gawkrodger, DJ; Kemp, EH; Watson, PF; Weetman, AP1
Bianchi, G; Kuznetsova, T; Li, Y; Staessen, JA; Struijker-Boudier, H; Thijs, L; Zagato, L1
Birmingham, DJ; Bottini, N; Cantor, RM; Farwell, L; Graham, DS; Grossman, JM; Hahn, BH; Hebert, LA; Jager, PL; Julkunen, H; Kere, J; Lingren, CM; Rioux, JD; Rovin, BH; Tsao, BP; Vyse, TJ; Wallace, DJ; Wu, H; Yu, CY1
Ala-Kokko, L; Leino-Arjas, P; Lohiniva, J; Luoma, K; Raininko, R; Riihimäki, H; Solovieva, S1
Egawa, H; Goto, T; Hamada, D; Inoue, H; Itakura, M; Kubo, T; Matsui, Y; Nakano, S; Shinomiya, F; Takata, Y; Yasui, N1
Csanády, M; Sepp, R1
Diksic, M; Hasegawa, S; Nishi, K; Overstreet, DH; Watanabe, A1
Capdevielle, C; Eymard, B; Gajdos, P; Garchon, HJ; Giraud, M; Jais, JP; Krumeich, S; Tranchant, C; Vandiedonck, C1
Butt, C; Gladman, D; Greenwood, C; Hamilton, S; Peddle, L; Rahman, P1
Sher, L1
Burns, TM; Dimberg, EL; Klein, CJ; Phillips, LH; Vaught, BK1
Bassi, A; Corrocher, R; Friso, S; Girelli, D; Malerba, G; Martinelli, N; Olivieri, O; Pignatti, PF; Pizzolo, F; Sandri, M; Trabetti, E1
Arnett, DK; Black, H; Boerwinkle, E; Davis, BR; Eckfeldt, JH; Ford, CE; Leiendecker-Foster, C; Miller, MB1
Browndyke, J; Ghio, A; Schmechel, DE1
Görgens, H; Hoffmann, T; Noack, B; Schackert, HK1
Chiba, K; Ikegawa, S; Kawaguchi, Y; Kimura, T; Kubo, T; Mikami, Y; Mio, F; Mori, M; Seki, S; Toyama, Y; Tsunoda, T1
Choi, SJ; Ji, JD; Lee, YH; Rho, YH; Song, GG1
Fuchs, M; Hay, B; Klass, DM; Kratzer, W; Lauer, N1
Cheng, KC; Connor, JR; Goodman, SI; Housman, C; Jacobs, RE; LaNoue, K; Lazovic, J; O'Callaghan, JP; Simpson, I; Woontner, M; Zinnanti, WJ1
Ashley-Koch, A; Barefoot, JC; Brummett, BH; Gadde, KM; Helms, MJ; Kuhn, CM; Lane, JD; Marchuk, DA; Schanberg, SM; Siegler, IC; Suarez, EC; Surwit, RS; Svenson, IK; Williams, RB1
Bouchard, C; Mauriège, P1
Bertina, RM; Landolfi, R; Poort, SR1
Heikkinen, S; Kekäläinen, P; Kuopusjärvi, J; Kuusisto, J; Laakso, M; Pihlajamäki, J; Rissanen, J; Sipiläinen, R; Vanhala, M1
Ala-Kokko, L; Annunen, S; Göring, HH; Karppinen, J; Kröger, H; Lähde, S; Lohiniva, J; Ott, J; Paassilta, P; Perälä, M; Pihlajamaa, T; Prockop, DJ; Ryhänen, L; Tervonen, O; Vanharanta, H1
Deutz, NE; Honig, A; Klaassen, T; Riedel, WJ; van Praag, HM; van Someren, A1
Allen, J; Delgado, PL; Gelenberg, AJ; Heninger, GR; McKnight, KM; Moreno, FA; Phillips, AP; Potter, RL1
Benkelfat, C; LeMarquand, DG; Palmour, RM; Pihl, RO; Young, SN1
Barlassina, C; Bianchi, G; Candy, GC; Citterio, L; Cusi, D; Norton, GR; Radevski, I; Samani, NJ; Woodwiss, AJ1
Boerwinkle, E1
Ala-Kokko, L; Göring, HH; Hakala, M; Kaitila, I; Karppinen, J; Kröger, H; Lohiniva, J; Ott, J; Paassilta, P; Palm, T; Perälä, M; Räinä, SS; Vanharanta, H1
Marini, JC1
Alonso, V; Corella, D; Folch, J; Guillén, M; Portolés, O; Sáiz, C; Sorlí, JV1
Sabra, M; Shuldiner, AR1
Aan Het Rot, M; Booij, I; Deutz, NE; Honig, A; Riedel, WJ; Sobczak, S1
Ackenheil, M; Bondy, B; de Zwaan, M; Kasper, S; Konstantinidis, A; Neumeister, A; Praschak-Rieder, N; Schwarz, MJ; Stastny, J; Vitouch, O; Willeit, M; Zach, J1

Reviews

15 review(s) available for tryptophan and Genetic Predisposition

ArticleYear
Caspase recruitment domain 9, microbiota, and tryptophan metabolism: dangerous liaisons in inflammatory bowel diseases.
    Current opinion in clinical nutrition and metabolic care, 2017, Volume: 20, Issue:4

    Topics: Animals; CARD Signaling Adaptor Proteins; Colitis; Gastrointestinal Microbiome; Genetic Predisposition to Disease; Humans; Inflammatory Bowel Diseases; Interleukin-22; Interleukins; Mice; Mice, Knockout; Receptors, Aryl Hydrocarbon; Tryptophan

2017
Targeting classical IL-6 signalling or IL-6 trans-signalling in depression?
    Expert opinion on therapeutic targets, 2014, Volume: 18, Issue:5

    Topics: Acute-Phase Reaction; Animals; Antidepressive Agents; Autoimmunity; Bacterial Translocation; Cytokines; Depression; Depressive Disorder; Disease Models, Animal; Genetic Predisposition to Disease; Humans; Hypothalamo-Hypophyseal System; Inflammation; Interleukin-6; Meta-Analysis as Topic; Molecular Targeted Therapy; Neurodegenerative Diseases; Neuroimmunomodulation; Neurotransmitter Agents; Pituitary-Adrenal System; Receptors, Interleukin-6; Signal Transduction; Stress, Psychological; T-Lymphocyte Subsets; Tryptophan; Zinc

2014
Does serotonin deficit mediate susceptibility to ADHD?
    Neurochemistry international, 2015, Volume: 82

    Topics: Adolescent; Animals; Animals, Newborn; Attention Deficit Disorder with Hyperactivity; Central Nervous System Stimulants; Child; Child, Preschool; Corpus Striatum; Disease Models, Animal; Dopamine; Gene-Environment Interaction; Genetic Association Studies; Genetic Predisposition to Disease; Humans; Inhibition, Psychological; Mice, Knockout; Multifactorial Inheritance; Nerve Tissue Proteins; Neurotransmitter Transport Proteins; Oxidopamine; Prefrontal Cortex; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Serotonin, 5-HT1B; Selective Serotonin Reuptake Inhibitors; Serotonin; Tryptophan

2015
The role of serotonin in impulsive aggression, suicide, and homicide in adolescents and adults: a literature review.
    International journal of adolescent medicine and health, 2015, Volume: 27, Issue:2

    Topics: Adolescent; Aggression; Animals; Brain; Child; Environment; Genetic Predisposition to Disease; Homicide; Humans; Impulsive Behavior; Magnetic Resonance Imaging; Positron-Emission Tomography; Receptors, Neurotransmitter; Risk Factors; Selective Serotonin Reuptake Inhibitors; Serotonin; Serotonin Plasma Membrane Transport Proteins; Sex Factors; Suicide; Tryptophan; United States

2015
The tryptophan 620 allele of the lymphoid tyrosine phosphatase (PTPN22) gene predisposes to autoimmune Addison's disease.
    Clinical endocrinology, 2009, Volume: 70, Issue:3

    Topics: Addison Disease; Autoimmune Diseases; Case-Control Studies; Gene Frequency; Genetic Predisposition to Disease; Genotype; Humans; Poland; Polymorphism, Single Nucleotide; Protein Tyrosine Phosphatase, Non-Receptor Type 22; Tryptophan; United Kingdom; White People

2009
The Arg194Trp polymorphism in the X-ray repair cross-complementing group 1 gene as a potential risk factor of oral cancer: a meta-analysis.
    The Tohoku journal of experimental medicine, 2009, Volume: 219, Issue:1

    Topics: Arginine; Asia; Carcinoma, Squamous Cell; DNA-Binding Proteins; Europe; Gene Frequency; Genetic Predisposition to Disease; Heterozygote; Homozygote; Humans; Mouth Neoplasms; Odds Ratio; Polymorphism, Single Nucleotide; Tryptophan; X-ray Repair Cross Complementing Protein 1

2009
Tryptophan kynurenine metabolism as a common mediator of genetic and environmental impacts in major depressive disorder: the serotonin hypothesis revisited 40 years later.
    The Israel journal of psychiatry and related sciences, 2010, Volume: 47, Issue:1

    Topics: Adrenal Cortex Hormones; Animals; Biosynthetic Pathways; Cytokines; Depressive Disorder, Major; Environment; Genetic Predisposition to Disease; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interferon-gamma; Kynurenine; Serotonin; Stress, Psychological; Tryptophan; Tryptophan Oxygenase; Tumor Necrosis Factor-alpha; Up-Regulation

2010
Targeting tryptophan hydroxylase 2 in affective disorder.
    Expert opinion on therapeutic targets, 2010, Volume: 14, Issue:11

    Topics: Animals; Antidepressive Agents; Drug Design; Drug Resistance; Enzyme Inhibitors; Genetic Predisposition to Disease; Humans; Mood Disorders; Polymorphism, Genetic; Psychotropic Drugs; Serotonin; Tryptophan; Tryptophan Hydroxylase

2010
α-adducin Gly460Trp polymorphism and essential hypertension risk in Chinese: a meta-analysis.
    Hypertension research : official journal of the Japanese Society of Hypertension, 2011, Volume: 34, Issue:3

    Topics: Adult; Aged; Asian People; Calmodulin-Binding Proteins; China; Female; Genetic Association Studies; Genetic Predisposition to Disease; Glycine; Homozygote; Humans; Hypertension; Male; Middle Aged; Polymorphism, Genetic; Tryptophan

2011
Complement factor B polymorphism 32W protects against age-related macular degeneration.
    Molecular vision, 2011, Apr-20, Volume: 17

    Topics: Aged; Aged, 80 and over; Arginine; Case-Control Studies; Complement Activation; Complement Factor B; Complement Factor H; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Glutamine; Haplotypes; High-Temperature Requirement A Serine Peptidase 1; Humans; Linkage Disequilibrium; Macular Degeneration; Male; Middle Aged; Odds Ratio; Polymorphism, Single Nucleotide; Retina; Risk Factors; Serine Endopeptidases; Smoking; Tryptophan

2011
X-ray repair cross-complementing group 1 (XRCC1) genetic polymorphisms and cervical cancer risk: a huge systematic review and meta-analysis.
    PloS one, 2012, Volume: 7, Issue:9

    Topics: Arginine; Asian People; DNA Damage; DNA-Binding Proteins; Female; Genetic Predisposition to Disease; Glutamine; Humans; Odds Ratio; Polymorphism, Genetic; Risk; Risk Factors; Tryptophan; Uterine Cervical Neoplasms; X-ray Repair Cross Complementing Protein 1

2012
[Beta3-adrenergic receptor gene polymorphism in diabetes].
    Nihon rinsho. Japanese journal of clinical medicine, 2005, Volume: 63 Suppl 2

    Topics: Adipocytes; Amino Acid Substitution; Arginine; Diabetes Mellitus; Genetic Predisposition to Disease; Humans; Lipid Metabolism; Mutation, Missense; Racial Groups; Receptors, Adrenergic, beta-3; Tryptophan

2005
Combined analysis of 635 patients confirms an age-related association of the serotonin 2A receptor gene with tardive dyskinesia and specificity for the non-orofacial subtype.
    The international journal of neuropsychopharmacology, 2005, Volume: 8, Issue:3

    Topics: Adult; Aged; Aging; Analysis of Variance; Chi-Square Distribution; Dyskinesia, Drug-Induced; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Histidine; Humans; International Cooperation; Logistic Models; Male; Middle Aged; Mutation; Polymorphism, Genetic; Receptor, Serotonin, 5-HT2A; Tryptophan

2005
[The long QT syndrome from the bedside to molecular genetic laboratory. The history of the first described Hungarian family].
    Orvosi hetilap, 2005, Sep-25, Volume: 146, Issue:39

    Topics: Cysteine; Electrocardiography; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Genetic Linkage; Genetic Predisposition to Disease; Humans; Hungary; Lod Score; Long QT Syndrome; Mutation, Missense; Pedigree; Tryptophan

2005
All for one and one for all: introduction to a coordinated analysis of the Gly-460-Trp alpha-adducin polymorphism.
    American journal of hypertension, 2000, Volume: 13, Issue:6 Pt 1

    Topics: Alleles; Blood Pressure; Calmodulin-Binding Proteins; Cytoskeletal Proteins; Genetic Markers; Genetic Predisposition to Disease; Humans; Hypertension; Incidence; Point Mutation; Polymorphism, Genetic; Tryptophan

2000

Trials

9 trial(s) available for tryptophan and Genetic Predisposition

ArticleYear
SLC6A4 polymorphisms modulate the efficacy of a tryptophan-enriched diet on age-related depression and social cognition.
    Clinical nutrition (Edinburgh, Scotland), 2021, Volume: 40, Issue:4

    Topics: Age Factors; Alleles; Depression; Diet; Diet Surveys; Eating; Empathy; Female; Genetic Association Studies; Genetic Predisposition to Disease; Genotype; Healthy Volunteers; Humans; Hydroxyindoleacetic Acid; Male; Middle Aged; Nutritional Physiological Phenomena; Polymorphism, Genetic; Psychological Tests; Serotonin Plasma Membrane Transport Proteins; Single-Blind Method; Social Cognition; Tryptophan; Young Adult

2021
Serotonin transporter genotype and depressive phenotype determination by discriminant analysis of glucose metabolism under acute tryptophan depletion.
    NeuroImage, 2008, Volume: 43, Issue:4

    Topics: Adult; Brain; Depression; Discriminant Analysis; Female; Fluorodeoxyglucose F18; Genetic Predisposition to Disease; Glucose; Humans; Male; Phenotype; Placebo Effect; Positron-Emission Tomography; Radiopharmaceuticals; Serotonin Plasma Membrane Transport Proteins; Tryptophan

2008
Alteration of frontal EEG asymmetry during tryptophan depletion predicts future depression.
    Journal of affective disorders, 2009, Volume: 115, Issue:1-2

    Topics: Adult; Affect; Depressive Disorder; Dominance, Cerebral; Double-Blind Method; Early Diagnosis; Electroencephalography; Female; Follow-Up Studies; Frontal Lobe; Genetic Predisposition to Disease; Humans; Male; Middle Aged; Predictive Value of Tests; Risk Assessment; Serotonin; Tryptophan

2009
Acute tryptophan depletion effects on the vertex and late positive potentials to emotional faces in individuals with a family history of depression.
    Neuropsychobiology, 2012, Volume: 65, Issue:1

    Topics: Adolescent; Adult; Affect; Amino Acids; Depressive Disorder; Double-Blind Method; Emotions; Evoked Potentials; Facial Expression; Female; Genetic Predisposition to Disease; Humans; Male; Middle Aged; Pattern Recognition, Visual; Serotonin; Tryptophan

2012
Antihypertensive therapy, the alpha-adducin polymorphism, and cardiovascular disease in high-risk hypertensive persons: the Genetics of Hypertension-Associated Treatment Study.
    The pharmacogenomics journal, 2007, Volume: 7, Issue:2

    Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Calmodulin-Binding Proteins; Chlorthalidone; Coronary Disease; Double-Blind Method; Doxazosin; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Glycine; Humans; Hypertension; Incidence; Kaplan-Meier Estimate; Lisinopril; Male; Middle Aged; Patient Selection; Polymorphism, Genetic; Proportional Hazards Models; Risk Assessment; Risk Factors; Sex Factors; Time Factors; Treatment Outcome; Tryptophan

2007
Mood effects of 24-hour tryptophan depletion in healthy first-degree relatives of patients with affective disorders.
    Biological psychiatry, 1999, Aug-15, Volume: 46, Issue:4

    Topics: Adolescent; Cross-Over Studies; Depression; Double-Blind Method; Family; Female; Genetic Predisposition to Disease; Humans; Male; Middle Aged; Mood Disorders; Psychiatric Status Rating Scales; Reference Values; Sex Characteristics; Tryptophan

1999
Tryptophan depletion and depressive vulnerability.
    Biological psychiatry, 1999, Aug-15, Volume: 46, Issue:4

    Topics: Adult; Aged; Biomarkers; Cross-Over Studies; Depression; Double-Blind Method; Female; Genetic Predisposition to Disease; Humans; Male; Mood Disorders; Psychiatric Status Rating Scales; Recurrence; Serotonin; Sex Characteristics; Tryptophan

1999
Cognition following acute tryptophan depletion: difference between first-degree relatives of bipolar disorder patients and matched healthy control volunteers.
    Psychological medicine, 2002, Volume: 32, Issue:3

    Topics: Administration, Oral; Adult; Amino Acids; Bipolar Disorder; Cognition Disorders; Double-Blind Method; Female; Frontal Lobe; Genetic Predisposition to Disease; Humans; Male; Middle Aged; Neuropsychological Tests; Risk; Serotonin; Tryptophan

2002
Association between serotonin transporter gene promoter polymorphism (5HTTLPR) and behavioral responses to tryptophan depletion in healthy women with and without family history of depression.
    Archives of general psychiatry, 2002, Volume: 59, Issue:7

    Topics: Adult; Carrier Proteins; Depressive Disorder; Family; Female; Genetic Predisposition to Disease; Genotype; Humans; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Placebos; Polymorphism, Genetic; Promoter Regions, Genetic; Risk Factors; Serotonin; Serotonin Plasma Membrane Transport Proteins; Tryptophan

2002

Other Studies

76 other study(ies) available for tryptophan and Genetic Predisposition

ArticleYear
Genetic susceptibility loci for
    Frontiers in immunology, 2022, Volume: 13

    Topics: Chlamydia Infections; Chlamydia trachomatis; Female; Genetic Markers; Genetic Predisposition to Disease; Humans; Quantitative Trait Loci; RNA, Messenger; T-Lymphocytes; Tryptophan

2022
Urine 6-Bromotryptophan: Associations with Genetic Variants and Incident End-Stage Kidney Disease.
    Scientific reports, 2020, 06-22, Volume: 10, Issue:1

    Topics: Amino Acid Transport Systems, Neutral; Female; Genetic Predisposition to Disease; Genetic Variation; Glomerular Filtration Rate; Humans; Kidney Failure, Chronic; Male; Membrane Glycoproteins; Middle Aged; Oxidoreductases; Proportional Hazards Models; Risk Factors; Tryptophan

2020
Association of RASgrf1 methylation with epileptic seizures.
    Oncotarget, 2017, Jul-11, Volume: 8, Issue:28

    Topics: Animals; Brain; Disease Models, Animal; DNA Methylation; Epilepsy; Gene Expression; Genetic Association Studies; Genetic Predisposition to Disease; Male; Mice; Mice, Knockout; Phthalimides; Pyramidal Cells; ras-GRF1; Seizures; Tryptophan

2017
A novel gene mutation of Runx2 in cleidocranial dysplasia.
    Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, 2017, Volume: 37, Issue:5

    Topics: Adult; Amino Acid Substitution; Cleidocranial Dysplasia; Core Binding Factor Alpha 1 Subunit; Exons; Female; Genetic Predisposition to Disease; Histidine; Humans; Mutation, Missense; Pedigree; Sequence Analysis, DNA; Tryptophan

2017
Cerebral tryptophan metabolism and outcome of tuberculous meningitis: an observational cohort study.
    The Lancet. Infectious diseases, 2018, Volume: 18, Issue:5

    Topics: Adult; Cohort Studies; Female; Genetic Predisposition to Disease; Genotype; Humans; Male; Metabolome; Tryptophan; Tuberculosis, Meningeal; Young Adult

2018
XRCC1 Arg194Trp and Arg399Gln polymorphisms are significantly associated with shorter survival in acute myeloid leukemia.
    Leukemia & lymphoma, 2014, Volume: 55, Issue:2

    Topics: Acute Disease; Adult; Aged; Amino Acid Substitution; Arginine; DNA-Binding Proteins; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Glutamine; Humans; Leukemia, Myeloid; Male; Middle Aged; Polymorphism, Genetic; Risk Factors; Survival Analysis; Tryptophan; X-ray Repair Cross Complementing Protein 1

2014
Tryptophan to Glycine mutation in the position 116 leads to protein aggregation and decreases the stability of the LITAF protein.
    Journal of biomolecular structure & dynamics, 2015, Volume: 33, Issue:8

    Topics: Codon; Genetic Predisposition to Disease; Glycine; Humans; Hydrogen Bonding; Models, Molecular; Molecular Dynamics Simulation; Mutation; Nuclear Proteins; Polymorphism, Single Nucleotide; Protein Aggregation, Pathological; Protein Conformation; Protein Stability; Reproducibility of Results; Structure-Activity Relationship; Transcription Factors; Tryptophan

2015
IDO1 and IDO2 non-synonymous gene variants: correlation with crohn's disease risk and clinical phenotype.
    PloS one, 2014, Volume: 9, Issue:12

    Topics: Adult; Case-Control Studies; Crohn Disease; Female; Genetic Predisposition to Disease; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Male; Middle Aged; Phenotype; Polymorphism, Single Nucleotide; Tryptophan

2014
The Effects of Tryptophan on Everyday Interpersonal Encounters and Social Cognitions in Individuals with a Family History of Depression.
    The international journal of neuropsychopharmacology, 2015, Mar-02, Volume: 18, Issue:8

    Topics: Activities of Daily Living; Adolescent; Adult; Affect; Aged; Antidepressive Agents, Second-Generation; Cognition; Cross-Over Studies; Depressive Disorder; Double-Blind Method; Family; Female; Genetic Predisposition to Disease; Housing; Humans; Interpersonal Relations; Male; Middle Aged; Psychiatric Status Rating Scales; Social Behavior; Tryptophan; Young Adult

2015
Functional characterization of the RYR1 mutation p.Arg4737Trp associated with susceptibility to malignant hyperthermia.
    Neuromuscular disorders : NMD, 2016, Volume: 26, Issue:1

    Topics: Anesthetics; Arginine; B-Lymphocytes; Caffeine; Cell Line, Transformed; Cresols; Family Health; Female; Fungicides, Industrial; Genetic Predisposition to Disease; Germany; Halothane; Humans; Male; Malignant Hyperthermia; Muscle Contraction; Muscle, Skeletal; Phosphodiesterase Inhibitors; Polymorphism, Single Nucleotide; Ryanodine Receptor Calcium Release Channel; Tryptophan

2016
Association of XRCC1 Trp194 allele with risk of breast cancer, and Ki67 protein status in breast tumor tissues.
    Saudi medical journal, 2016, Volume: 37, Issue:6

    Topics: Adult; Alleles; Breast Neoplasms; Cross-Sectional Studies; DNA-Binding Proteins; Female; Genetic Predisposition to Disease; Humans; Iran; Ki-67 Antigen; Middle Aged; Polymorphism, Single Nucleotide; Tryptophan; X-ray Repair Cross Complementing Protein 1

2016
The expanding genetic overlap between multiple sclerosis and type I diabetes.
    Genes and immunity, 2009, Volume: 10, Issue:1

    Topics: Adaptor Proteins, Signal Transducing; Adult; Alleles; Amino Acid Substitution; Antigens, Differentiation, T-Lymphocyte; Australia; Belgium; Case-Control Studies; Confidence Intervals; Diabetes Mellitus, Type 1; Family; Genetic Predisposition to Disease; Humans; Lectins, C-Type; Linkage Disequilibrium; Middle Aged; Monosaccharide Transport Proteins; Multiple Sclerosis; Norway; Odds Ratio; Polymorphism, Single Nucleotide; Probability; Sweden; Tryptophan; United Kingdom; United States

2009
Examination of association of genes in the serotonin system to autism.
    Neurogenetics, 2009, Volume: 10, Issue:3

    Topics: Adolescent; Autistic Disorder; Child; Child, Preschool; Genetic Predisposition to Disease; Humans; Linkage Disequilibrium; Molecular Sequence Data; Molecular Structure; Polymorphism, Single Nucleotide; Serotonin; Tryptophan; Young Adult

2009
A novel mutation (F71L) in alphaA-crystallin with defective chaperone-like function associated with age-related cataract.
    Biochimica et biophysica acta, 2009, Volume: 1792, Issue:10

    Topics: Aging; alpha-Crystallin A Chain; Amino Acid Substitution; Base Sequence; Case-Control Studies; Cataract; Chromatography, Gel; Circular Dichroism; DNA Mutational Analysis; Electrophoresis, Polyacrylamide Gel; Exons; Female; Genetic Predisposition to Disease; Humans; Light; Male; Middle Aged; Molecular Sequence Data; Mutant Proteins; Mutation; Protein Structure, Quaternary; Scattering, Radiation; Spectrometry, Fluorescence; Time Factors; Tryptophan

2009
Association between genetic polymorphism of XRCC1 Arg194Trp and risk of schizophrenia.
    Psychiatry research, 2009, Sep-30, Volume: 169, Issue:2

    Topics: Arginine; Case-Control Studies; Chi-Square Distribution; DNA-Binding Proteins; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Humans; Male; Polymorphism, Single Nucleotide; Risk Factors; Schizophrenia; Tryptophan; X-ray Repair Cross Complementing Protein 1

2009
The unfolding of the prion protein sheds light on the mechanisms of prion susceptibility and species barrier.
    Biochemistry, 2009, Sep-15, Volume: 48, Issue:36

    Topics: Animals; Arginine; Cricetinae; Genetic Predisposition to Disease; Glutamine; Mice; Mutagenesis, Site-Directed; Prion Diseases; Prion Proteins; Prions; Protein Denaturation; Protein Folding; Species Specificity; Thermodynamics; Tryptophan

2009
Polymorphisms of XRCC1 gene and risk of gastric cardiac adenocarcinoma.
    Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus, 2009, Volume: 22, Issue:5

    Topics: Adenine; Adenocarcinoma; Adult; Aged; Arginine; Cardia; Case-Control Studies; Codon; Cytosine; DNA Repair; DNA-Binding Proteins; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Glutamine; Haplotypes; Histidine; Humans; Linkage Disequilibrium; Male; Middle Aged; Polymorphism, Single Nucleotide; Risk Factors; Smoking; Stomach Neoplasms; Thymine; Tryptophan; X-ray Repair Cross Complementing Protein 1

2009
Immunogenetic risk and protective factors for the development of L-tryptophan-associated eosinophilia-myalgia syndrome and associated symptoms.
    Arthritis and rheumatism, 2009, Oct-15, Volume: 61, Issue:10

    Topics: Adult; Disease Outbreaks; Eosinophilia-Myalgia Syndrome; Female; Genetic Predisposition to Disease; HLA-DQ alpha-Chains; HLA-DQ Antigens; HLA-DR Antigens; HLA-DRB1 Chains; Humans; Immunoglobulin Gm Allotypes; Immunoglobulin Km Allotypes; Male; Middle Aged; Molecular Epidemiology; Risk Factors; Tryptophan

2009
Two novel mutations in thymidine kinase-2 cause early onset fatal encephalomyopathy and severe mtDNA depletion.
    Neuromuscular disorders : NMD, 2010, Volume: 20, Issue:3

    Topics: Adenosine Triphosphate; Arginine; Child; Child, Preschool; DNA Mutational Analysis; DNA, Mitochondrial; Female; Genetic Predisposition to Disease; Humans; Infant; Infant, Newborn; Male; Mitochondria; Mitochondria, Muscle; Mitochondrial Diseases; Mitochondrial Encephalomyopathies; Muscle, Skeletal; Mutagenesis, Site-Directed; Mutation; Thymidine Kinase; Tryptophan

2010
The carriage of the type 1 diabetes-associated R262W variant of human LNK correlates with increased proliferation of peripheral blood monocytes in diabetic patients.
    Pediatric diabetes, 2011, Volume: 12, Issue:2

    Topics: Adaptor Proteins, Signal Transducing; Adolescent; Adult; Amino Acid Substitution; Arginine; Blood Cell Count; Case-Control Studies; Cell Proliferation; Child; Cross-Sectional Studies; Diabetes Mellitus, Type 1; Female; Genetic Predisposition to Disease; Heterozygote; Humans; Intracellular Signaling Peptides and Proteins; Male; Monocytes; Polymorphism, Single Nucleotide; Proteins; Tryptophan; Up-Regulation; Young Adult

2011
Association of polymorphism of DNA repair gene XRCC1 with sporadic late-onset Alzheimer's disease and age of onset in elderly Han Chinese.
    Journal of the neurological sciences, 2010, Aug-15, Volume: 295, Issue:1-2

    Topics: Aged; Aged, 80 and over; Alzheimer Disease; Apolipoproteins E; Arginine; Asian People; DNA-Binding Proteins; Female; Gene Frequency; Genetic Predisposition to Disease; Genome-Wide Association Study; Genotype; Humans; Male; Mental Status Schedule; Polymorphism, Genetic; Tryptophan; X-ray Repair Cross Complementing Protein 1

2010
Substitution (γ335Trp→Arg) in fibrinogen Fremantle causes diminished γ chain expression and increased sialic acid content.
    Thrombosis and haemostasis, 2010, Volume: 104, Issue:6

    Topics: Adult; Amino Acid Substitution; Arginine; Blood Coagulation; Blood Coagulation Disorders, Inherited; Female; Fibrinogen; Fibrinogens, Abnormal; Genetic Predisposition to Disease; Heredity; Humans; Middle Aged; Mutation; N-Acetylneuraminic Acid; Pedigree; Phenotype; Protein Conformation; Structure-Activity Relationship; Tryptophan

2010
Transgenic overexpression of Anks6(p.R823W) causes polycystic kidney disease in rats.
    The American journal of pathology, 2010, Volume: 177, Issue:6

    Topics: Amino Acid Substitution; Animals; Arginine; Gene Expression; Genetic Predisposition to Disease; Male; Mutant Proteins; Nuclear Proteins; Polycystic Kidney Diseases; Polymorphism, Single Nucleotide; Rats; Rats, Sprague-Dawley; Rats, Transgenic; Tryptophan; Up-Regulation

2010
JAK2V617F mutation is associated with special alleles in essential thrombocythemia.
    Leukemia & lymphoma, 2011, Volume: 52, Issue:3

    Topics: Alleles; Amino Acid Substitution; DNA Mutational Analysis; Gene Frequency; Genetic Linkage; Genetic Predisposition to Disease; Genetic Testing; Humans; Janus Kinase 2; Leucine; Lysine; Mutation, Missense; Phenylalanine; Polymorphism, Single Nucleotide; Receptors, Thrombopoietin; Thrombocythemia, Essential; Tryptophan; Valine

2011
Type IX collagen neo-deposition in degenerative discs of surgical patients whether genotyped plus or minus for COL9 risk alleles.
    Spine, 2011, Nov-15, Volume: 36, Issue:24

    Topics: Adult; Aged; Alleles; Blotting, Western; Collagen Type IX; Female; Genetic Predisposition to Disease; Genotype; Humans; Immunohistochemistry; Intervertebral Disc Degeneration; Intervertebral Disc Displacement; Lumbar Vertebrae; Male; Middle Aged; Polymorphism, Single Nucleotide; Risk Factors; Spinal Fractures; Spinal Stenosis; Spondylolisthesis; Tryptophan; Young Adult

2011
Taking pain out of NGF: a "painless" NGF mutant, linked to hereditary sensory autonomic neuropathy type V, with full neurotrophic activity.
    PloS one, 2011, Feb-28, Volume: 6, Issue:2

    Topics: Amino Acid Substitution; Animals; Arginine; BALB 3T3 Cells; Cells, Cultured; Chick Embryo; Genetic Predisposition to Disease; Hereditary Sensory and Autonomic Neuropathies; Humans; Male; Mice; Mutant Proteins; Nerve Growth Factors; Pain; Pain Perception; PC12 Cells; Rats; Receptor, Nerve Growth Factor; Sensory Receptor Cells; Tryptophan

2011
Survival bias and drug interaction can attenuate cross-sectional case-control comparisons of genes with health outcomes. An example of the kinesin-like protein 6 (KIF6) Trp719Arg polymorphism and coronary heart disease.
    BMC medical genetics, 2011, Mar-24, Volume: 12

    Topics: Arginine; Canada; Case-Control Studies; Comparative Genomic Hybridization; Computer Simulation; Coronary Disease; Cross-Sectional Studies; Drug Interactions; Genetic Predisposition to Disease; Genotype; Heterozygote; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kinesins; Logistic Models; Myocardial Infarction; Odds Ratio; Polymorphism, Single Nucleotide; Prospective Studies; Research Design; Risk Assessment; Risk Factors; Selection Bias; Survival Analysis; Treatment Outcome; Tryptophan

2011
L-tryptophan-mediated enhancement of susceptibility to nonalcoholic fatty liver disease is dependent on the mammalian target of rapamycin.
    The Journal of biological chemistry, 2011, Oct-07, Volume: 286, Issue:40

    Topics: Adenoviridae; Animal Feed; Animals; Aromatic-L-Amino-Acid Decarboxylases; Fatty Liver; Fibrosis; Fructose; Genetic Predisposition to Disease; Hepatocytes; Kynurenine; Lipids; Male; Mice; Mice, Inbred C57BL; Serotonin; TOR Serine-Threonine Kinases; Triglycerides; Tryptophan

2011
Frequency Determination of α-1,3 Glucosyltransferase p.Y131H and p.F304S Polymorphisms in the Croatian Population Revealed Five Novel Single Nucleotide Polymorphisms in the hALG6 Gene.
    Genetic testing and molecular biomarkers, 2012, Volume: 16, Issue:1

    Topics: Adult; Amino Acid Substitution; Base Sequence; Croatia; Female; Gene Frequency; Genetic Predisposition to Disease; Genetics, Population; Glucosyltransferases; Humans; Male; Membrane Proteins; Middle Aged; Phenylalanine; Polymorphism, Single Nucleotide; Serine; Tryptophan; Tyrosine; Young Adult

2012
Association of XRCC1, XRCC3, and NAT2 polymorphisms with the risk of oral submucous fibrosis among eastern Indian population.
    Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 2012, Volume: 41, Issue:4

    Topics: Adult; Areca; Arginine; Arylamine N-Acetyltransferase; Case-Control Studies; Codon; DNA Repair; DNA-Binding Proteins; Female; Genetic Predisposition to Disease; Glutamic Acid; Glutamine; Glycine; Heterozygote; Homozygote; Humans; India; Lysine; Male; Methionine; Multifactor Dimensionality Reduction; Oral Submucous Fibrosis; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Risk Factors; Threonine; Tobacco, Smokeless; Tryptophan; X-ray Repair Cross Complementing Protein 1

2012
Genetic polymorphisms (at codons 194 and 399) in the DNA repair gene XRCC1 and susceptibility to bipolar disorder.
    Psychiatry research, 2012, Jun-30, Volume: 198, Issue:1

    Topics: Bipolar Disorder; Case-Control Studies; DNA-Binding Proteins; Female; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Genotype; Glutamine; Humans; Linkage Disequilibrium; Male; Polymorphism, Genetic; Tryptophan; X-ray Repair Cross Complementing Protein 1

2012
Screening for POLG W748S and A467T mutations in ataxia patients from Spain.
    Movement disorders : official journal of the Movement Disorder Society, 2012, Sep-01, Volume: 27, Issue:10

    Topics: Adult; Age of Onset; Aged; Alanine; Ataxia; DNA Polymerase gamma; DNA-Directed DNA Polymerase; Female; Gene Frequency; Genetic Predisposition to Disease; Genetic Testing; Genotype; Humans; Male; Middle Aged; Mutation; Polymorphism, Single Nucleotide; Serine; Spain; Threonine; Tryptophan; Young Adult

2012
Allelic variants of XRCC1 and XRCC3 repair genes and susceptibility of oral cancer in Brazilian patients.
    Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 2013, Volume: 42, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Alleles; Arginine; Carcinoma, Squamous Cell; Case-Control Studies; Codon; DNA Repair; DNA-Binding Proteins; Female; Gene Frequency; Genetic Predisposition to Disease; Genetic Variation; Genotype; Glutamine; Humans; Lymphatic Metastasis; Male; Methionine; Middle Aged; Mouth Neoplasms; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Risk Factors; Threonine; Tryptophan; X-ray Repair Cross Complementing Protein 1; Young Adult

2013
ACE2 links amino acid malnutrition to microbial ecology and intestinal inflammation.
    Nature, 2012, Jul-25, Volume: 487, Issue:7408

    Topics: Angiotensin-Converting Enzyme 2; Animals; Biocatalysis; Colitis; Dextran Sulfate; Diarrhea; Dietary Proteins; Female; Gene Deletion; Genetic Predisposition to Disease; Germ-Free Life; Homeostasis; Immunity, Innate; Intestines; Male; Malnutrition; Metagenome; Mice; Models, Biological; Niacinamide; Peptidyl-Dipeptidase A; Renin-Angiotensin System; TOR Serine-Threonine Kinases; Trinitrobenzenesulfonic Acid; Tryptophan

2012
XRCC1 gene polymorphisms and risk of ameloblastoma.
    Archives of oral biology, 2013, Volume: 58, Issue:6

    Topics: Adenine; Adult; Ameloblastoma; Arginine; Codon; DNA Repair; DNA-Binding Proteins; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Glycine; Guanine; Haplotypes; Histidine; Humans; Male; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Risk Factors; Sequence Analysis, DNA; Thailand; Thymine; Tryptophan; X-ray Repair Cross Complementing Protein 1

2013
PAX4 mutation (R121W) as a prodiabetic variant in Okinawans.
    Biochemical and biophysical research communications, 2003, Mar-07, Volume: 302, Issue:2

    Topics: Aged; Amino Acid Substitution; Arginine; Diabetes Mellitus; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Homeodomain Proteins; Humans; Japan; Male; Mutation; Paired Box Transcription Factors; Transcription Factors; Tryptophan

2003
Identification of novel GDAP1 mutations causing autosomal recessive Charcot-Marie-Tooth disease.
    Neuromuscular disorders : NMD, 2003, Volume: 13, Issue:9

    Topics: Alleles; Arginine; Charcot-Marie-Tooth Disease; Cysteine; Demyelinating Diseases; DNA Mutational Analysis; Electrophysiology; Family Health; Female; Genetic Predisposition to Disease; Glycine; Histidine; Humans; Male; Microscopy, Electron; Mutation; Nerve Tissue Proteins; Neural Conduction; Pedigree; Peripheral Nerves; Sequence Analysis, DNA; Tryptophan

2003
Lower high-density lipoprotein cholesterol and increased omega-6 polyunsaturated fatty acids in first-degree relatives of bipolar patients.
    Psychological medicine, 2004, Volume: 34, Issue:1

    Topics: Adult; Analysis of Variance; Bipolar Disorder; Cholesterol; Cholesterol, LDL; Control Groups; Fatty Acids, Omega-3; Fatty Acids, Omega-6; Female; Genetic Markers; Genetic Predisposition to Disease; Humans; Hydrocortisone; Male; Mental Status Schedule; Middle Aged; Netherlands; Nuclear Family; Prolactin; Tryptophan

2004
The role of collagen IX tryptophan polymorphisms in symptomatic intervertebral disc disease in Southern European patients.
    Spine, 2004, Jun-01, Volume: 29, Issue:11

    Topics: Adult; Collagen Type IX; Cross-Sectional Studies; Female; Gene Frequency; Genetic Predisposition to Disease; Greece; Humans; Intervertebral Disc Displacement; Male; Polymorphism, Genetic; Tryptophan

2004
The association of lumbar spondylolisthesis with collagen IX tryptophan alleles.
    The Journal of bone and joint surgery. British volume, 2004, Volume: 86, Issue:7

    Topics: Adolescent; Adult; Aged; Alleles; Case-Control Studies; Collagen Type IX; Female; Genetic Predisposition to Disease; Humans; Lumbar Vertebrae; Magnetic Resonance Imaging; Male; Middle Aged; Polymorphism, Genetic; Radiography; Risk Factors; Spinal Stenosis; Spondylolisthesis; Tryptophan

2004
[A twin study of association of beta3AR Trp64Arg polymorphisms with insulin sensitivity].
    Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences, 2004, Volume: 36, Issue:5

    Topics: Arginine; Diseases in Twins; Gene Frequency; Genetic Predisposition to Disease; Genotype; Humans; Insulin; Insulin Resistance; Polymorphism, Genetic; Receptors, Adrenergic, beta-3; Tryptophan; Twins, Dizygotic

2004
Two novel mutations in the beta-myosin heavy chain gene associated with dilated cardiomyopathy.
    European journal of heart failure, 2004, Volume: 6, Issue:7

    Topics: Adolescent; Adult; Aged; Arginine; Blood Pressure; Cardiomyopathy, Dilated; Child; Female; Finland; Follow-Up Studies; Genetic Predisposition to Disease; Glutamine; Heart Failure; Humans; Hypertrophy, Left Ventricular; Male; Middle Aged; Mutation; Myosin Heavy Chains; Pedigree; Phenotype; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Sarcomeres; Stroke Volume; Tropomyosin; Troponin C; Troponin I; Troponin T; Tryptophan; Ventricular Myosins

2004
Association of R602W in a protein tyrosine phosphatase gene with a high risk of rheumatoid arthritis in a British population: evidence for an early onset/disease severity effect.
    Arthritis and rheumatism, 2005, Volume: 52, Issue:1

    Topics: Adult; Age of Onset; Arginine; Arthritis, Rheumatoid; England; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Humans; Male; Middle Aged; Mutation, Missense; Polymorphism, Single Nucleotide; Protein Tyrosine Phosphatase, Non-Receptor Type 22; Protein Tyrosine Phosphatases; Severity of Illness Index; Tryptophan; White People

2005
TLR2 Arg677Trp polymorphism in leprosy: revisited.
    Human genetics, 2005, Volume: 116, Issue:5

    Topics: Arginine; Base Sequence; Case-Control Studies; Genetic Predisposition to Disease; Genetic Variation; Humans; Leprosy, Lepromatous; Membrane Glycoproteins; Molecular Sequence Data; Polymorphism, Genetic; Promoter Regions, Genetic; Receptors, Cell Surface; Toll-Like Receptor 2; Toll-Like Receptors; Tryptophan

2005
Trp64Arg polymorphism of the beta3-adrenergic receptor gene, pre-pregnancy obesity and risk of pre-eclampsia.
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2005, Volume: 17, Issue:1

    Topics: Adult; Arginine; Body Mass Index; Case-Control Studies; Female; Gene Frequency; Genetic Predisposition to Disease; Heterozygote; Humans; Logistic Models; Obesity; Odds Ratio; Polymorphism, Genetic; Pre-Eclampsia; Pregnancy; Receptors, Adrenergic, beta-3; Tryptophan

2005
The frequency of Trp64Arg polymorphism of the beta3-adrenergic receptor gene in healthy and obese Hungarian children and its association with cardiovascular risk factors.
    European journal of clinical nutrition, 2005, Volume: 59, Issue:8

    Topics: Alleles; Arginine; Blood Glucose; Cardiovascular Diseases; Case-Control Studies; Child; DNA Fragmentation; Female; Genetic Predisposition to Disease; Glucose Tolerance Test; Humans; Hungary; Hypertension; Insulin; Male; Obesity; Polymerase Chain Reaction; Polymorphism, Genetic; Proteins; Receptors, Adrenergic, beta-3; Tryptophan

2005
CARD15/NOD2 polymorphisms do not explain concordance of Crohn's disease in Swedish monozygotic twins.
    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 2005, Volume: 37, Issue:10

    Topics: Adolescent; Adult; Arginine; Case-Control Studies; Child; Crohn Disease; Female; Frameshift Mutation; Gene Frequency; Genetic Predisposition to Disease; Genotype; Glycine; Humans; Intracellular Signaling Peptides and Proteins; Leucine; Male; Middle Aged; Nod2 Signaling Adaptor Protein; Polymorphism, Genetic; Sweden; Tryptophan; Twins, Monozygotic

2005
A single-nucleotide polymorphism in the gene encoding lymphoid protein tyrosine phosphatase (PTPN22) confers susceptibility to generalised vitiligo.
    Genes and immunity, 2005, Volume: 6, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Alleles; Case-Control Studies; Female; Genetic Predisposition to Disease; Humans; Male; Microfilament Proteins; Middle Aged; Mutation, Missense; Polymorphism, Single Nucleotide; Protein Tyrosine Phosphatase, Non-Receptor Type 22; Protein Tyrosine Phosphatases; Tryptophan; Vitiligo

2005
Cardiovascular risk in relation to alpha-adducin Gly460Trp polymorphism and systolic pressure: a prospective population study.
    Hypertension (Dallas, Tex. : 1979), 2005, Volume: 46, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Blood Pressure; Calmodulin-Binding Proteins; Cardiovascular Diseases; Child; Female; Genetic Predisposition to Disease; Genotype; Glycine; Humans; Hypertension; Male; Middle Aged; Polymorphism, Genetic; Prospective Studies; Risk; Tryptophan

2005
Association analysis of the R620W polymorphism of protein tyrosine phosphatase PTPN22 in systemic lupus erythematosus families: increased T allele frequency in systemic lupus erythematosus patients with autoimmune thyroid disease.
    Arthritis and rheumatism, 2005, Volume: 52, Issue:8

    Topics: Arginine; Autoimmune Diseases; Cohort Studies; Gene Frequency; Genetic Predisposition to Disease; Humans; Lupus Erythematosus, Systemic; Polymorphism, Genetic; Protein Tyrosine Phosphatase, Non-Receptor Type 22; Protein Tyrosine Phosphatases; Thyroid Diseases; Tryptophan; White People

2005
Intervertebral disc degeneration in relation to the COL9A3 and the IL-1ss gene polymorphisms.
    European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2006, Volume: 15, Issue:5

    Topics: Adult; Body Mass Index; Cohort Studies; Collagen Type IX; DNA Mutational Analysis; Fibrocartilage; Gene Frequency; Genetic Predisposition to Disease; Genetic Testing; Humans; Interleukin-1; Intervertebral Disc; Intervertebral Disc Displacement; Lumbar Vertebrae; Magnetic Resonance Imaging; Male; Middle Aged; Mutation; Occupational Exposure; Polymorphism, Genetic; Tryptophan

2006
The alpha 2 type IX collagen gene tryptophan polymorphism is not associated with rheumatoid arthritis in the Japanese population.
    Clinical rheumatology, 2006, Volume: 25, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Collagen Type IX; Female; Gene Frequency; Genetic Markers; Genetic Predisposition to Disease; Humans; Japan; Male; Middle Aged; Odds Ratio; Polymorphism, Genetic; Tryptophan

2006
Brain 5-HT synthesis in the Flinders Sensitive Line rat model of depression: an autoradiographic study.
    Neurochemistry international, 2006, Volume: 48, Issue:5

    Topics: Animals; Autoradiography; Brain Chemistry; Carbon Radioisotopes; Depressive Disorder; Disease Models, Animal; Down-Regulation; Genetic Predisposition to Disease; Limbic System; Neural Pathways; Neurons; Prosencephalon; Radioligand Assay; Raphe Nuclei; Rats; Rats, Mutant Strains; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin; Synaptic Transmission; Tryptophan

2006
Association of the PTPN22*R620W polymorphism with autoimmune myasthenia gravis.
    Annals of neurology, 2006, Volume: 59, Issue:2

    Topics: Adult; Aged; Alleles; Arginine; Confidence Intervals; Connectin; DNA Mutational Analysis; Female; Gene Frequency; Genetic Predisposition to Disease; Humans; Male; Middle Aged; Muscle Proteins; Myasthenia Gravis; Odds Ratio; Polymorphism, Genetic; Protein Kinases; Protein Tyrosine Phosphatase, Non-Receptor Type 22; Protein Tyrosine Phosphatases; Tryptophan

2006
Association of functional variants of PTPN22 and tp53 in psoriatic arthritis: a case-control study.
    Arthritis research & therapy, 2006, Volume: 8, Issue:1

    Topics: Adult; Arginine; Arthritis, Psoriatic; Case-Control Studies; Cohort Studies; Female; Gene Frequency; Genetic Predisposition to Disease; Genetic Variation; Genotype; Humans; Male; Newfoundland and Labrador; Ontario; Protein Tyrosine Phosphatase, Non-Receptor Type 22; Protein Tyrosine Phosphatases; Risk; Tryptophan; Tumor Suppressor Protein p53; White People

2006
Tryptophan depletion and alcoholism research.
    The Australian and New Zealand journal of psychiatry, 2006, Volume: 40, Issue:3

    Topics: Alcoholism; Comorbidity; Depressive Disorder, Major; Drive; Genetic Predisposition to Disease; Humans; Research; Tryptophan

2006
Novel myelin protein zero mutation (Arg36Trp) in a patient with acute onset painful neuropathy.
    Neuromuscular disorders : NMD, 2006, Volume: 16, Issue:5

    Topics: Acute Disease; Amino Acid Substitution; Arginine; Disease Progression; DNA Mutational Analysis; Genetic Predisposition to Disease; Genetic Testing; Hereditary Sensory and Motor Neuropathy; Humans; Inheritance Patterns; Male; Middle Aged; Myelin P0 Protein; Neuralgia; Peripheral Nerves; Peripheral Nervous System Diseases; Point Mutation; Polyradiculoneuropathy, Chronic Inflammatory Demyelinating; Time Factors; Tryptophan

2006
The -1131 T>C and S19W APOA5 gene polymorphisms are associated with high levels of triglycerides and apolipoprotein C-III, but not with coronary artery disease: an angiographic study.
    Atherosclerosis, 2007, Volume: 191, Issue:2

    Topics: Adult; Aged; Apolipoprotein A-V; Apolipoprotein C-III; Apolipoproteins A; Coronary Angiography; Coronary Artery Disease; Cytosine; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Humans; Hypertriglyceridemia; Linear Models; Male; Middle Aged; Odds Ratio; Phenotype; Polymorphism, Single Nucleotide; Risk Assessment; Risk Factors; Serine; Thymine; Triglycerides; Tryptophan

2007
Strategies for dissecting genetic-environmental interactions in neurodegenerative disorders.
    Neurotoxicology, 2006, Volume: 27, Issue:5

    Topics: Adult; Age Factors; Age of Onset; Aged; Aged, 80 and over; Aging; alpha 1-Antitrypsin; Analysis of Variance; Apolipoprotein E4; Apolipoproteins E; Chi-Square Distribution; Cysteine; DNA Mutational Analysis; Environment; Female; Gene Frequency; Genetic Predisposition to Disease; Hemochromatosis; Humans; Male; Middle Aged; Mutation; Neurodegenerative Diseases; Phenotype; Retrospective Studies; Tryptophan

2006
CARD15 gene variants in aggressive periodontitis.
    Journal of clinical periodontology, 2006, Volume: 33, Issue:11

    Topics: Adult; Arginine; Base Sequence; Case-Control Studies; Cytosine; Disease Susceptibility; DNA Transposable Elements; Exons; Female; Gene Frequency; Genetic Predisposition to Disease; Genetic Variation; Glycine; Guanine; Humans; Male; Middle Aged; Mutation; Nod2 Signaling Adaptor Protein; Periodontitis; Thymine; Tryptophan

2006
Association study of COL9A2 with lumbar disc disease in the Japanese population.
    Journal of human genetics, 2006, Volume: 51, Issue:12

    Topics: Adult; Aged, 80 and over; Alleles; Asian People; Collagen Type IX; DNA Mutational Analysis; Genetic Predisposition to Disease; Genetic Variation; Haplotypes; Humans; Intervertebral Disc; Lumbar Vertebrae; Middle Aged; Polymorphism, Single Nucleotide; Spinal Diseases; Tryptophan

2006
The association between hyperuricemia and the Trp64Arg polymorphism of the beta-3 adrenergic receptor.
    Rheumatology international, 2007, Volume: 27, Issue:9

    Topics: Adult; Amino Acid Sequence; Amino Acid Substitution; Arginine; DNA Mutational Analysis; Gene Frequency; Genetic Markers; Genetic Predisposition to Disease; Genetic Testing; Genotype; Humans; Hyperuricemia; Male; Middle Aged; Point Mutation; Polymorphism, Genetic; Receptors, Adrenergic, beta-3; Sex Factors; Tryptophan

2007
Arg64 variant of the beta3-adrenergic receptor is associated with gallstone formation.
    The American journal of gastroenterology, 2007, Volume: 102, Issue:11

    Topics: Arginine; Body Mass Index; Cross-Sectional Studies; DNA Mutational Analysis; Female; Gallstones; Gene Frequency; Genetic Predisposition to Disease; Genotype; Germany; Humans; Logistic Models; Male; Middle Aged; Mutation, Missense; Polymorphism, Genetic; Receptors, Adrenergic, beta-3; Tryptophan

2007
Association analysis of gamma2 subunit of gamma-aminobutyric acid (GABA) type A receptor and voltage-gated sodium channel type II alpha-polypeptide gene mutation in southern Chinese children with febrile seizures.
    Journal of child neurology, 2007, Volume: 22, Issue:6

    Topics: Arginine; Chi-Square Distribution; Child; Child, Preschool; China; DNA Mutational Analysis; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Humans; Infant; Lysine; Male; Methionine; Mutation; NAV1.2 Voltage-Gated Sodium Channel; Nerve Tissue Proteins; Polymorphism, Single Nucleotide; Receptors, GABA-A; Seizures, Febrile; Sodium Channels; Tryptophan

2007
Mechanism of age-dependent susceptibility and novel treatment strategy in glutaric acidemia type I.
    The Journal of clinical investigation, 2007, Volume: 117, Issue:11

    Topics: Aging; Amino Acid Metabolism, Inborn Errors; Animals; Brain Diseases, Metabolic, Inborn; Child; Diet; Disease Models, Animal; gamma-Aminobutyric Acid; Genetic Predisposition to Disease; Glucose; Glutamic Acid; Glutarates; Glutaryl-CoA Dehydrogenase; Homoarginine; Humans; Lysine; Mice; Mice, Knockout; Mitochondria; Neurons; Nuclear Magnetic Resonance, Biomolecular; Tryptophan

2007
Childhood socioeconomic status and serotonin transporter gene polymorphism enhance cardiovascular reactivity to mental stress.
    Psychosomatic medicine, 2008, Volume: 70, Issue:1

    Topics: Adult; Aged; Alleles; Blood Pressure; Cardiovascular Diseases; Educational Status; Fathers; Female; Genetic Predisposition to Disease; Heart Rate; Humans; Income; Male; Middle Aged; Polymorphism, Genetic; Serotonin; Serotonin Plasma Membrane Transport Proteins; Social Class; Stress, Psychological; Tryptophan

2008
Trp64Arg mutation in beta 3-adrenoceptor gene of doubtful significance for obesity and insulin resistance.
    Lancet (London, England), 1996, Sep-14, Volume: 348, Issue:9029

    Topics: Animals; Arginine; Diabetes Mellitus, Type 2; Genetic Predisposition to Disease; Heterozygote; Humans; Insulin Resistance; Mutation; Obesity; Receptors, Adrenergic, beta; Receptors, Adrenergic, beta-3; Tryptophan

1996
Compound heterozygosity for two novel missense mutations in the prothrombin gene in a patient with a severe bleeding tendency.
    Thrombosis and haemostasis, 1997, Volume: 77, Issue:4

    Topics: Blood Coagulation Factors; Cysteine; Female; Genetic Predisposition to Disease; Genetic Variation; Hemorrhage; Heterozygote; Humans; Hypoprothrombinemias; Infant, Newborn; Point Mutation; Prothrombin; Reference Values; Sequence Analysis, DNA; Tryptophan; Tyrosine

1997
The Trp64Arg polymorphism of the beta 3-Adrenergic receptor gene. Lack of association with NIDDM and features of insulin resistance syndrome.
    Diabetes care, 1997, Volume: 20, Issue:8

    Topics: Adult; Alleles; Arginine; Diabetes Mellitus, Type 2; DNA; DNA Primers; Exons; Female; Finland; Gene Frequency; Genetic Predisposition to Disease; Humans; Insulin Resistance; Male; Middle Aged; Polymerase Chain Reaction; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Receptors, Adrenergic, beta; Receptors, Adrenergic, beta-3; Syndrome; Tryptophan

1997
An allele of COL9A2 associated with intervertebral disc disease.
    Science (New York, N.Y.), 1999, Jul-16, Volume: 285, Issue:5426

    Topics: Adult; Aged; Alleles; Amino Acid Substitution; Case-Control Studies; Codon; Collagen; Collagen Type IX; Female; Genetic Linkage; Genetic Predisposition to Disease; Humans; Intervertebral Disc Displacement; Linkage Disequilibrium; Male; Middle Aged; Mutation; Penetrance; Polymorphism, Genetic; Sciatica; Tryptophan

1999
Behavioral disinhibition induced by tryptophan depletion in nonalcoholic young men with multigenerational family histories of paternal alcoholism.
    The American journal of psychiatry, 1999, Volume: 156, Issue:11

    Topics: Affect; Age Factors; Aggression; Alcohol Drinking; Alcoholism; Avoidance Learning; Disruptive, Impulse Control, and Conduct Disorders; Family; Genetic Predisposition to Disease; Humans; Impulsive Behavior; Male; Mental Disorders; Serotonin; Smoking; Synaptic Transmission; Tryptophan

1999
Alpha-adducin polymorphism in hypertensives of South African ancestry.
    American journal of hypertension, 2000, Volume: 13, Issue:6 Pt 1

    Topics: Adult; Alleles; Blood Pressure; Calmodulin-Binding Proteins; Cytoskeletal Proteins; DNA; DNA Primers; Female; Gene Frequency; Genetic Predisposition to Disease; Genotype; Humans; Hypertension; Male; Middle Aged; Point Mutation; Polymerase Chain Reaction; Polymorphism, Genetic; Prevalence; Retrospective Studies; South Africa; Tryptophan

2000
Identification of a novel common genetic risk factor for lumbar disk disease.
    JAMA, 2001, Apr-11, Volume: 285, Issue:14

    Topics: Adult; Aged; Alleles; Arginine; Case-Control Studies; Collagen; Collagen Type IX; DNA Mutational Analysis; Electrophoresis; Finland; Genetic Predisposition to Disease; Humans; Intervertebral Disc Displacement; Lumbar Vertebrae; Magnetic Resonance Imaging; Middle Aged; Point Mutation; Polymerase Chain Reaction; Risk Factors; Tomography, X-Ray Computed; Tryptophan

2001
Genetic risk factors for lumbar disk disease.
    JAMA, 2001, Apr-11, Volume: 285, Issue:14

    Topics: Collagen; Collagen Type IX; Genetic Predisposition to Disease; Humans; Intervertebral Disc Displacement; Lumbar Vertebrae; Point Mutation; Tryptophan

2001
Gender specific associations of the Trp64Arg mutation in the beta3-adrenergic receptor gene with obesity-related phenotypes in a Mediterranean population: interaction with a common lipoprotein lipase gene variation.
    Journal of internal medicine, 2001, Volume: 250, Issue:4

    Topics: Adolescent; Adult; Aged; Alleles; Arginine; Body Mass Index; Body Weight; DNA Mutational Analysis; Female; Genetic Carrier Screening; Genetic Predisposition to Disease; Genetic Variation; Humans; Lipoprotein Lipase; Male; Middle Aged; Obesity; Phenotype; Receptors, Adrenergic, beta-3; Sex Factors; Spain; Tryptophan

2001
Trp64Arg beta3-adrenoceptor: when does a candidate gene become a disease-susceptibility gene?
    Obesity research, 2001, Volume: 9, Issue:12

    Topics: Arginine; Body Mass Index; Genetic Predisposition to Disease; Genetic Variation; Humans; Prospective Studies; Receptors, Adrenergic, beta-3; Tryptophan

2001