tryptophan and Fibrosis

tryptophan has been researched along with Fibrosis in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (10.53)18.2507
2000's3 (15.79)29.6817
2010's9 (47.37)24.3611
2020's5 (26.32)2.80

Authors

AuthorsStudies
Di Pasquale, P; Dischinger, K; Dreger, P; Luft, T; Monteagudo, E; Müller-Tidow, C; Orsatti, L; Radujkovic, A; Speziale, R; Stiehl, T1
Chiara, JL; Chiara, MD; El Aidy, S; Ioannidis, M; Jansma, J; Maassen, S; Maierhofer, L; Markus, H; van den Bogaart, G; Warner, H; Weavers, H1
Aala, WJ; Chen, YF; Chen, YL; Hou, PC; Hsu, CK; Lin, YC; Lu, HC; McGrath, JA; Onoufriadis, A1
Cao, K; Chen, C; Li, H; Wang, Q; Zuo, S1
Čepcová, D; Deelman, LE; Kema, IP; Klimas, J; Sandovici, M; Šišková, K; Vavrincová-Yaghi, D; Vavrinec, P1
Albejante, MC; Amaral, TA; Bach, EE; Brito, RBO; Camacho, CP; Dalboni, MA; Dellê, H; Malta, CS; Matheus, LHG; Matos, YST; Rodrigues, GGC; Santana, AC; Simão, GM1
Eschenhagen, T; Foo, RS; Geertz, B; Hirt, MN; Höppner, G; Löser, A; Ng, SL; Peters, BS; Reichenspurner, H; Schaefer, A; Schneeberger, Y; Stenzig, J; Tan, W; Wong, E; Zhao, RR1
Dolivo, DM; Dominko, T; Larson, SA1
Argyopoulos, CP; Bayliss, GP; Cao, G; Chen, DQ; Chen, H; Chen, L; Cheng, XH; Guo, Y; Kang, H; Li, XR; Liu, D; Ma, SX; Mao, JR; Meng, MX; Samuels, DC; Shang, YQ; Su, W; Vaziri, ND; Wang, M; Ye, F; Yu, H; Yu, XY; Zhang, L; Zhang, Y; Zhao, J; Zhao, S; Zhao, YY; Zhuang, S1
Ahn, MS; Ahn, SG; Eom, YW; Kim, JY; Lee, JH; Lee, JW; Lee, SH; Oh, JE; Park, SW; Rhee, KJ; Son, JW; Yoo, BS; Yoon, J; Youn, YJ1
Cattaneo, C; Eckert, D; Garzotti, M; Groenen, PM; Nayler, O; Segrestaa, J; Sieber, P; Studer, R; Trébaul, A; Vercauteren, M; Welford, RW1
Hoshi, M; Ito, H; Kanamori, H; Moriwaki, H; Nagaki, M; Ohtaki, H; Osawa, Y; Saito, K; Seishima, M; Seki, E; Suetsugu, A; Yasuda, Y1
Schulman, G2
Homma, T; Hoseki, J; Ishida, Y; Kato, K; Koide, T; Kurimoto, E; Nagata, K; Nishi, Y; Nishikawa, Y; Yagi-Utsumi, M; Yamaguchi, Y; Yoshikawa, S1
Gong, SX; Liu, JY; Liu, MG; Peng, JH; Tang, ZH; Wang, Q; Xu, CQ; Zhang, XQ; Zhou, X1
Al-Tassan, NA; Khalil, DS; Khan, AO1
Jimenez, SA; Uitto, J; Varga, J1
Falanga, V; Greenberg, AS; Hasan, A; Hill, RH; Murata, H; Takagi, H1

Reviews

3 review(s) available for tryptophan and Fibrosis

ArticleYear
Tryptophan metabolites kynurenine and serotonin regulate fibroblast activation and fibrosis.
    Cellular and molecular life sciences : CMLS, 2018, Volume: 75, Issue:20

    Topics: Cell Differentiation; Fibroblasts; Fibrosis; Humans; Kynurenine; Receptors, Aryl Hydrocarbon; Serotonin; Signal Transduction; Transforming Growth Factor beta; Tryptophan

2018
A nexus of progression of chronic kidney disease: tryptophan, profibrotic cytokines, and charcoal.
    Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation, 2012, Volume: 22, Issue:1

    Topics: Adsorption; Carbon; Disease Progression; Fibrosis; Humans; Indican; Intestinal Absorption; Kidney Failure, Chronic; Microspheres; Oxides; Renin-Angiotensin System; Transforming Growth Factor beta; Tryptophan

2012
L-tryptophan and the eosinophilia-myalgia syndrome: current understanding of the etiology and pathogenesis.
    The Journal of investigative dermatology, 1993, Volume: 100, Issue:1

    Topics: Animals; Autoimmunity; Drug Contamination; Eosinophilia-Myalgia Syndrome; Eosinophils; Fibrosis; Humans; Tryptophan

1993

Trials

1 trial(s) available for tryptophan and Fibrosis

ArticleYear
A nexus of progression of chronic kidney disease: charcoal, tryptophan and profibrotic cytokines.
    Blood purification, 2006, Volume: 24, Issue:1

    Topics: Administration, Oral; Adult; Aged; Carbon; Cytokines; Endpoint Determination; Female; Fibrosis; Humans; Indican; Kidney; Kidney Failure, Chronic; Male; Middle Aged; Oxides; Tryptophan

2006

Other Studies

15 other study(ies) available for tryptophan and Fibrosis

ArticleYear
Kynurenine pathway activation and deviation to anthranilic and kynurenic acid in fibrosing chronic graft-versus-host disease.
    Cell reports. Medicine, 2021, 10-19, Volume: 2, Issue:10

    Topics: Adolescent; Adult; Aged; Chemokine CXCL9; Female; Fibrosis; Gene Expression Regulation; Graft vs Host Disease; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Interleukin-18; Kynurenic Acid; Kynurenine; Kynurenine 3-Monooxygenase; Leukemia; Lymphoma; Male; Metabolic Networks and Pathways; Middle Aged; ortho-Aminobenzoates; Retrospective Studies; Riboflavin; Severity of Illness Index; Signal Transduction; Stem Cell Transplantation; Transplantation, Homologous; Tryptophan; Vitamin B 6

2021
Mitochondrial interaction of fibrosis-protective 5-methoxy tryptophan enhances collagen uptake by macrophages.
    Free radical biology & medicine, 2022, 08-01, Volume: 188

    Topics: Collagen; Fibrosis; Humans; Macrophages; Mitochondria; Tryptophan

2022
Plasma metabolomic profiling reflects the malnourished and chronic inflammatory state in recessive dystrophic epidermolysis bullosa.
    Journal of dermatological science, 2022, Volume: 107, Issue:2

    Topics: Chromatography, Liquid; Epidermolysis Bullosa Dystrophica; Fibrosis; Glutamates; Glutamine; Humans; Inflammation; Kynurenine; Malnutrition; Phenylalanine; Succinates; Tandem Mass Spectrometry; Tryptophan; Tyrosine

2022
Integrative analysis of the gut microbiota and faecal and serum short-chain fatty acids and tryptophan metabolites in patients with cirrhosis and hepatic encephalopathy.
    Journal of translational medicine, 2023, 06-17, Volume: 21, Issue:1

    Topics: Fatty Acids, Volatile; Feces; Fibrosis; Gastrointestinal Microbiome; Hepatic Encephalopathy; Humans; Inflammation; Liver Cirrhosis; RNA, Ribosomal, 16S; Tryptophan

2023
The protective effect of 1-methyltryptophan isomers in renal ischemia-reperfusion injury is not exclusively dependent on indolamine 2,3-dioxygenase inhibition.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2021, Volume: 135

    Topics: Animals; Coculture Techniques; Dendritic Cells; Disease Models, Animal; Enzyme Inhibitors; Epithelial-Mesenchymal Transition; Fibrosis; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kidney; Kidney Diseases; Lectins, C-Type; Mice; NIH 3T3 Cells; NK Cell Lectin-Like Receptor Subfamily K; Reperfusion Injury; Signal Transduction; T-Lymphocytes; THP-1 Cells; Toll-Like Receptor 4; Transforming Growth Factor beta; Tryptophan

2021
Indoleamine 2, 3-dioxygenase (IDO) increases during renal fibrogenesis and its inhibition potentiates TGF-β 1-induced epithelial to mesenchymal transition.
    BMC nephrology, 2017, Sep-06, Volume: 18, Issue:1

    Topics: Animals; Dogs; Epithelial-Mesenchymal Transition; Fibrosis; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kidney Diseases; Madin Darby Canine Kidney Cells; Male; Rats; Rats, Wistar; Transforming Growth Factor beta1; Tryptophan

2017
Pharmacological inhibition of DNA methylation attenuates pressure overload-induced cardiac hypertrophy in rats.
    Journal of molecular and cellular cardiology, 2018, Volume: 120

    Topics: Analysis of Variance; Animals; Cardiomegaly; CpG Islands; Disease Models, Animal; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Fibrosis; Gene Expression Regulation; Heart Failure; Magnetic Resonance Imaging; Male; Myocardium; Myocytes, Cardiac; Phthalimides; Rats; Rats, Wistar; Sequence Analysis, RNA; Thoracic Arteries; Tryptophan; Ventricular Function

2018
Identification of serum metabolites associating with chronic kidney disease progression and anti-fibrotic effect of 5-methoxytryptophan.
    Nature communications, 2019, 04-01, Volume: 10, Issue:1

    Topics: Acetylcarnitine; Animals; Canavanine; Carnitine; Case-Control Studies; Disease Models, Animal; Disease Progression; Fibrosis; Gene Knock-In Techniques; Gene Knockdown Techniques; Humans; I-kappa B Proteins; Inflammation; Kelch-Like ECH-Associated Protein 1; Kidney; Metabolomics; Mice; NF-E2-Related Factor 2; NF-kappa B; Renal Insufficiency, Chronic; Severity of Illness Index; Signal Transduction; Taurine; Tryptophan; Tryptophan Hydroxylase; Ureteral Obstruction

2019
Co-treatment with interferon-γ and 1-methyl tryptophan ameliorates cardiac fibrosis through cardiac myofibroblasts apoptosis.
    Molecular and cellular biochemistry, 2019, Volume: 458, Issue:1-2

    Topics: Autophagy; Cell Cycle Checkpoints; Fibrosis; Gene Expression Regulation; Humans; Interferon-gamma; Muscle Proteins; Myocardial Infarction; Myocardium; Myofibroblasts; Signal Transduction; Tryptophan

2019
Serotonin biosynthesis as a predictive marker of serotonin pharmacodynamics and disease-induced dysregulation.
    Scientific reports, 2016, 07-21, Volume: 6

    Topics: Animals; Disease Models, Animal; Fibrosis; Isotope Labeling; Lung Diseases, Interstitial; Rats; Serotonin; Serotonin Receptor Agonists; Tryptophan; Tryptophan Hydroxylase

2016
L-tryptophan-mediated enhancement of susceptibility to nonalcoholic fatty liver disease is dependent on the mammalian target of rapamycin.
    The Journal of biological chemistry, 2011, Oct-07, Volume: 286, Issue:40

    Topics: Adenoviridae; Animal Feed; Animals; Aromatic-L-Amino-Acid Decarboxylases; Fatty Liver; Fibrosis; Fructose; Genetic Predisposition to Disease; Hepatocytes; Kynurenine; Lipids; Male; Mice; Mice, Inbred C57BL; Serotonin; TOR Serine-Threonine Kinases; Triglycerides; Tryptophan

2011
NMR and mutational identification of the collagen-binding site of the chaperone Hsp47.
    PloS one, 2012, Volume: 7, Issue:9

    Topics: Animals; Binding Sites; Chickens; Collagen; Crystallography, X-Ray; DNA Mutational Analysis; Fibrosis; Histidine; HSP47 Heat-Shock Proteins; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Conformation; Mutagenesis, Site-Directed; Peptides; Protein Conformation; Protein Structure, Secondary; Protein Structure, Tertiary; Swine; Tryptophan

2012
Mutation p.Arg954Trp of KIF21A causes congenital fibrosis of the extraocular muscles in a Chinese family.
    Yi chuan xue bao = Acta genetica Sinica, 2006, Volume: 33, Issue:8

    Topics: Amino Acid Substitution; Arginine; Asian People; Female; Fibrosis; Humans; Kinesins; Male; Mutation; Oculomotor Muscles; Ophthalmoplegia; Pedigree; Tryptophan; Young Adult

2006
Congential fibrosis of the extraocular muscles type I (CFEOM1) on the Arabian Peninsula.
    Ophthalmic genetics, 2008, Volume: 29, Issue:1

    Topics: Adult; Arabs; Arginine; Blepharoptosis; Child, Preschool; Female; Fibrosis; Heterozygote; Humans; Kinesins; Male; Muscular Diseases; Mutation; Nerve Tissue Proteins; Oculomotor Muscles; Ophthalmoplegia; Pedigree; Saudi Arabia; Tryptophan

2008
Delayed onset of skin fibrosis after the ingestion of eosinophilia-myalgia syndrome-associated L-tryptophan.
    Journal of the American Academy of Dermatology, 1996, Volume: 35, Issue:2 Pt 1

    Topics: Adult; Eosinophilia-Myalgia Syndrome; Female; Fibrosis; Hand Dermatoses; Humans; Leg Dermatoses; Skin; Tryptophan

1996