tryptophan and Drug Withdrawal Symptoms

tryptophan has been researched along with Drug Withdrawal Symptoms in 45 studies

Research

Studies (45)

TimeframeStudies, this research(%)All Research%
pre-199027 (60.00)18.7374
1990's8 (17.78)18.2507
2000's6 (13.33)29.6817
2010's3 (6.67)24.3611
2020's1 (2.22)2.80

Authors

AuthorsStudies
Arnhard, K; Fuchs, D; Geisler, S; Gleissenthall, GV; Kemmler, G; Mechtcheriakov, S; Oberacher, H; Schurr, T; Unterberger, C1
Ahmed, S; Batool, F; Haleem, DJ1
Inoue, T; Kamba, T; Kamoto, T; Maeno, A; Nakamura, E; Ogawa, O; Shimizu, Y; Terada, N; Yoshida, T1
Hruby, VJ; Keresztes, AI; Largent-Milnes, TM; Roeske, WR; Tumati, S; Vanderah, TW; Varga, EV; Yamamoto, T1
Budac, DP; Gulinello, M; Li, Y; Pehrson, AL; Sánchez, C1
Ilivitsky, V; Knott, V; Mahoney, C; Perugini, M; Young, SN1
Epstein, OI; Pan, IR; Titkova, AM1
Berlin, I; Manéglier, B; Spreux-Varoquaux, O; Vorspan, F; Warot, D1
Bryant, SM; Kolodchak, J1
Delgado, PL1
Alphs, L; Davis, JM1
Banki, CM1
Herrera, E; Martín del Río, R; Mena, MA1
Kruszewska, A; Langwiński, R1
Colin, H; Friedman, MJ; Gaspar, M; Guiochon, G; Krstulović, AM; Pajer, KA1
Charney, DS; Heninger, GR; Sternberg, DE1
Badawy, AA; Evans, CM; Evans, M; Punjani, NF1
Badawy, AA; Evans, M; Punjani, NF2
Haleem, DJ; Haleem, MA; Yasmeen, A; Zafar, A1
Darmani, NA1
Fisher, H; Halladay, AK; Hsu, T; Sekowski, A; Wagner, GC1
Badawy, AA; Evans, M3
Agarwal, RA; Lapierre, YD; Rastogi, RB; Singhal, RL1
Hoffman, P; Moses, F; Tabakoff, B1
Brenner, A; Wapnir, RA1
Bunney, WE; Kopanda, RT; Murphy, DL1
Hartmann, E1
Hoffman, PL; Tabakoff, B1
Abu-Murad, C; Littleton, JM1
Morgan, PF1
Bowen, DJ; Fox, E; Spring, B1
Meltzer, HY; Parsa, MA; Ramirez, LF; Rohr, T1
Chadwick, MJ; Gregory, DL; Wendling, G1
Eagles, JM1
Pike, RF1
Schneider-Helmert, D; Spinweber, CL1
Badawy, AA1
Berman, ML; Tennant, F1
Goldstein, DB1
Algeri, S; Costa, E1
Grahame-Smith, DG; Marshall, I1
Norton, PR1

Reviews

1 review(s) available for tryptophan and Drug Withdrawal Symptoms

ArticleYear
Monoamine depletion studies: implications for antidepressant discontinuation syndrome.
    The Journal of clinical psychiatry, 2006, Volume: 67 Suppl 4

    Topics: Animals; Antidepressive Agents; Brain; Depressive Disorder; Dopamine; Humans; Norepinephrine; Selective Serotonin Reuptake Inhibitors; Serotonin; Substance Withdrawal Syndrome; Synapses; Tryptophan

2006

Trials

6 trial(s) available for tryptophan and Drug Withdrawal Symptoms

ArticleYear
Effects of tryptophan depletion on acute smoking abstinence symptoms and the acute smoking response.
    Pharmacology, biochemistry, and behavior, 2003, Volume: 74, Issue:3

    Topics: Adult; Affect; Analysis of Variance; Double-Blind Method; Electroencephalography; Humans; Male; Smoking; Smoking Cessation; Substance Withdrawal Syndrome; Tryptophan

2003
Effect of glucose on tobacco craving. Is it mediated by tryptophan and serotonin?
    Psychopharmacology, 2005, Volume: 178, Issue:1

    Topics: Administration, Oral; Adult; Affect; Behavior, Addictive; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Female; Glucose; Humans; Male; Reaction Time; Serotonin; Substance Withdrawal Syndrome; Tobacco Use Disorder; Tryptophan

2005
Serotonin function and mechanism of action of antidepressant treatment. Effects of amitriptyline and desipramine.
    Archives of general psychiatry, 1984, Volume: 41, Issue:4

    Topics: Aged; Amitriptyline; Animals; Brain Chemistry; Depressive Disorder; Desipramine; Female; Humans; Infant; Infusions, Parenteral; Male; Middle Aged; Placebos; Prolactin; Rats; Receptors, Serotonin; Serotonin; Stimulation, Chemical; Substance Withdrawal Syndrome; Time Factors; Tryptophan

1984
L-tryptophan: a rational hypnotic with clinical potential.
    The American journal of psychiatry, 1977, Volume: 134, Issue:4

    Topics: Animals; Brain Chemistry; Clinical Trials as Topic; Dose-Response Relationship, Drug; Female; Humans; Hypnotics and Sedatives; Male; Mental Disorders; Placebos; Rats; Serotonin; Sleep; Sleep Initiation and Maintenance Disorders; Stimulation, Chemical; Substance Withdrawal Syndrome; Tryptophan

1977
Tryptophan and high-carbohydrate diets as adjuncts to smoking cessation therapy.
    Journal of behavioral medicine, 1991, Volume: 14, Issue:2

    Topics: Adolescent; Adult; Anxiety; Behavior Therapy; Combined Modality Therapy; Diet; Dietary Carbohydrates; Humans; Middle Aged; Nicotine; Placebos; Smoking; Smoking Prevention; Substance Withdrawal Syndrome; Tryptophan; Weight Gain

1991
A double-blind amino acids, L-tryptophan and L-tyrosine, and placebo study with cocaine-dependent subjects in an inpatient chemical dependency treatment center.
    The American journal of drug and alcohol abuse, 1990, Volume: 16, Issue:3-4

    Topics: Adolescent; Adult; Cocaine; Double-Blind Method; Drug Administration Schedule; Female; Humans; Male; Middle Aged; MMPI; Substance Withdrawal Syndrome; Substance-Related Disorders; Tryptophan; Tyrosine

1990

Other Studies

38 other study(ies) available for tryptophan and Drug Withdrawal Symptoms

ArticleYear
Tryptophan-kynurenine metabolism during acute alcohol withdrawal in patients with alcohol use disorder: The role of immune activation.
    Alcoholism, clinical and experimental research, 2022, Volume: 46, Issue:9

    Topics: Alcohol Drinking; Alcoholism; Biomarkers; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenic Acid; Kynurenine; Neopterin; Quinolinic Acid; Substance Withdrawal Syndrome; Tryptophan

2022
Dietary supplementations of amino acids: evidence for enhanced serotonergic functions following haloperidol withdrawal in rat medial prefrontal cortex.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2009, Volume: 19, Issue:3

    Topics: Animals; Catalepsy; Dietary Supplements; Frontal Lobe; Haloperidol; Male; Rats; Rats, Wistar; Serotonin; Substance Withdrawal Syndrome; Tryptophan; Valine

2009
Antiandrogen withdrawal syndrome and alternative antiandrogen therapy associated with the W741C mutant androgen receptor in a novel prostate cancer xenograft.
    The Prostate, 2010, Feb-15, Volume: 70, Issue:3

    Topics: Administration, Oral; Androgen Antagonists; Androgens; Anilides; Animals; Antineoplastic Agents, Hormonal; Cysteine; Drug Administration Schedule; Flutamide; Humans; Male; Mice; Mutation; Neoplasm Transplantation; Nitriles; Prostatic Neoplasms; Receptors, Androgen; Retreatment; Substance Withdrawal Syndrome; Tosyl Compounds; Transplantation, Heterologous; Tryptophan

2010
Tachykinin NK₁ receptor antagonist co-administration attenuates opioid withdrawal-mediated spinal microglia and astrocyte activation.
    European journal of pharmacology, 2012, Jun-05, Volume: 684, Issue:1-3

    Topics: Analgesics, Opioid; Animals; Astrocytes; Biomarkers; CD11b Antigen; Hyperalgesia; Male; Microglia; Morphine; Nerve Tissue Proteins; Neurokinin-1 Receptor Antagonists; Rats; Rats, Sprague-Dawley; Spinal Cord; Substance Withdrawal Syndrome; Tryptophan; Tumor Necrosis Factor-alpha; Up-Regulation

2012
A rodent model of premenstrual dysphoria: progesterone withdrawal induces depression-like behavior that is differentially sensitive to classes of antidepressants.
    Behavioural brain research, 2012, Oct-01, Volume: 234, Issue:2

    Topics: Analysis of Variance; Animals; Antidepressive Agents; Autoradiography; Chromatography, High Pressure Liquid; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Estradiol; Female; Food Preferences; Hormones; Mood Disorders; Motor Activity; Nociception; Ovariectomy; Premenstrual Syndrome; Progesterone; Rats; Rats, Long-Evans; Serotonin; Serotonin Plasma Membrane Transport Proteins; Social Behavior; Substance Withdrawal Syndrome; Swimming; Tryptophan

2012
Effects of potentiated antibodies against brain-specific S100 protein on biogenic amine content and lipid peroxidation in rats under conditions of alcoholization.
    Bulletin of experimental biology and medicine, 2003, Volume: 135 Suppl 7

    Topics: Animals; Antibodies; Biogenic Amines; Brain; Dopamine; Epinephrine; Ethanol; Lipid Peroxidation; Male; Norepinephrine; Rats; S100 Proteins; Substance Withdrawal Syndrome; Tryptophan; Tyrosine

2003
Serotonin syndrome resulting from an herbal detox cocktail.
    The American journal of emergency medicine, 2004, Volume: 22, Issue:7

    Topics: Adult; Antidepressive Agents, Second-Generation; Humans; Hypericum; Male; N-Methyl-3,4-methylenedioxyamphetamine; Nonprescription Drugs; Plant Preparations; Self Medication; Serotonin Syndrome; Substance Withdrawal Syndrome; Tryptophan

2004
Noncatecholaminergic treatments of tardive dyskinesia.
    Journal of clinical psychopharmacology, 1982, Volume: 2, Issue:6

    Topics: Amantadine; Anti-Anxiety Agents; Benzodiazepines; Cyproheptadine; D-Ala(2),MePhe(4),Met(0)-ol-enkephalin; Double-Blind Method; Dyskinesia, Drug-Induced; Enkephalin, Methionine; gamma-Aminobutyric Acid; Humans; Lithium; Parasympathomimetics; Phenytoin; Receptors, Cell Surface; Receptors, Cholinergic; Receptors, GABA-A; Substance Withdrawal Syndrome; Tryptophan

1982
Factors influencing monoamine metabolites and tryptophan in patients with alcohol dependence.
    Journal of neural transmission, 1981, Volume: 50, Issue:2-4

    Topics: Alcoholism; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Kinetics; Phenylacetates; Reference Values; Substance Withdrawal Syndrome; Tryptophan

1981
The effect of long-term ethanol maternal ingestion and withdrawal on brain regional monoamine and amino acid precursors in 15-day-old rats.
    General pharmacology, 1984, Volume: 15, Issue:2

    Topics: Alcoholism; Amino Acids; Animals; Biogenic Amines; Brain Chemistry; Catecholamines; Female; Humans; Hydroxyindoleacetic Acid; Maternal-Fetal Exchange; Pregnancy; Pregnancy Complications; Rats; Rats, Inbred Strains; Serotonin; Substance Withdrawal Syndrome; Time Factors; Tryptophan; Tyrosine

1984
The role of central serotoninergic neurotransmission in the morphine abstinence syndrome in rats.
    Drug and alcohol dependence, 1983, Volume: 12, Issue:3

    Topics: 5-Hydroxytryptophan; Animals; Brain; Fenclonine; Humans; Male; Metergoline; Morphine; Rats; Rats, Inbred Strains; Serotonin; Substance Withdrawal Syndrome; Synaptic Transmission; Tryptophan

1983
Analytical methodology for assays of serum tryptophan metabolites in control subjects and newly abstinent alcoholics: preliminary investigation by liquid chromatography with amperometric detection.
    Journal of chromatography, 1984, Aug-03, Volume: 297

    Topics: Adult; Aged; Alcoholism; Chemical Phenomena; Chemistry; Chromatography, High Pressure Liquid; Humans; Kynurenine; Male; Middle Aged; Serotonin; Spectrophotometry, Ultraviolet; Substance Withdrawal Syndrome; Tryptophan

1984
Inhibition of rat brain tryptophan metabolism by ethanol withdrawal and possible involvement of the enhanced liver tryptophan pyrrolase activity.
    The Biochemical journal, 1980, Nov-15, Volume: 192, Issue:2

    Topics: Animals; Behavior, Animal; Brain; Corticosterone; Ethanol; Humans; Liver; Male; NAD; Rats; Serotonin; Substance Withdrawal Syndrome; Tryptophan; Tryptophan Oxygenase

1980
The effects of ethanol on rat liver and brain tryptophan metabolism.
    Substance and alcohol actions/misuse, 1980, Volume: 1, Issue:5-6

    Topics: Alcoholism; Animals; Brain Chemistry; Corticosterone; Ethanol; Humans; Liver; Male; Rats; Rats, Inbred Strains; Substance Withdrawal Syndrome; Tryptophan; Tryptophan Oxygenase

1980
The role of liver tryptophan pyrrolase in the opposite effects of chronic administration and subsequent withdrawal of drugs of dependence on rat brain tryptophan metabolism.
    The Biochemical journal, 1981, Apr-15, Volume: 196, Issue:1

    Topics: Animals; Brain; Humans; Liver; Male; Methylphenazonium Methosulfate; Morphine; Naloxone; Nicotine; Phenobarbital; Rats; Substance Withdrawal Syndrome; Tryptophan; Tryptophan Oxygenase

1981
24h withdrawal following repeated administration of caffeine attenuates brain serotonin but not tryptophan in rat brain: implications for caffeine-induced depression.
    Life sciences, 1995, Volume: 57, Issue:19

    Topics: Analysis of Variance; Animals; Brain; Caffeine; Depression; Dose-Response Relationship, Drug; Drug Administration Schedule; Hydroxyindoleacetic Acid; Male; Rats; Rats, Wistar; Serotonin; Substance Withdrawal Syndrome; Time Factors; Tryptophan

1995
Withdrawal from chronic cocaine administration causes prolonged deficits in L-tryptophan-induced head-twitch response in mice.
    Life sciences, 1997, Volume: 61, Issue:12

    Topics: Analysis of Variance; Animals; Cocaine; Drug Administration Schedule; Male; Mice; Mice, Inbred ICR; Monoamine Oxidase Inhibitors; Motor Activity; Opioid-Related Disorders; Serotonin; Stereotyped Behavior; Substance Withdrawal Syndrome; Time Factors; Tranylcypromine; Tryptophan

1997
Differential effects of monoaminergic agonists on alcohol intake in rats fed a tryptophan-enhanced diet.
    Alcohol (Fayetteville, N.Y.), 1999, Volume: 18, Issue:1

    Topics: Alcohol Drinking; Amphetamine; Animals; Appetite Depressants; Cerebral Cortex; Corpus Striatum; Dopamine; Fenfluramine; Food, Formulated; Hypothalamus; Phentermine; Rats; Rats, Long-Evans; Serotonin; Substance Withdrawal Syndrome; Tryptophan

1999
The effects of acute and chronic nicotine hydrogen (+)-tartrate administration and subsequent withdrawal on rat liver tryptophan pyrrolase activity and their comparison with those of morphine, phenobarbitone and ethanol.
    The Biochemical journal, 1975, Volume: 148, Issue:3

    Topics: Animals; Cycloheximide; Dactinomycin; Ethanol; Humans; Hydrocortisone; Liver; Male; Morphine; NADP; Nicotinyl Alcohol; Phenobarbital; Premedication; Pyridines; Rats; Substance Withdrawal Syndrome; Time Factors; Tryptophan; Tryptophan Oxygenase

1975
Alterations in brain 5-hydroxytryptamine metabolism during the 'withdrawal' phase after chronic treatment with diazepam and bromazepam.
    British journal of pharmacology, 1977, Volume: 60, Issue:1

    Topics: Animals; Anti-Anxiety Agents; Brain; Bromazepam; Diazepam; Humans; Hydroxyindoleacetic Acid; Male; Mesencephalon; Monoamine Oxidase; Rats; Serotonin; Substance Withdrawal Syndrome; Time Factors; Tryptophan; Tryptophan Hydroxylase

1977
Neurochemical correlates of ethanol withdrawal: alterations in serotoninergic function.
    The Journal of pharmacy and pharmacology, 1977, Volume: 29, Issue:8

    Topics: Alcoholism; Animals; Brain Chemistry; Brain Stem; Humans; Hydroxyindoleacetic Acid; Male; Mice; Mice, Inbred C57BL; Pargyline; Serotonin; Substance Withdrawal Syndrome; Time Factors; Tryptophan

1977
A pyridoxine-dependent behavioral disorder unmasked by isoniazid.
    American journal of diseases of children (1960), 1978, Volume: 132, Issue:8

    Topics: Child Behavior Disorders; Child, Preschool; Female; Humans; Hyperkinesis; Isoniazid; Kynurenine; Niacinamide; Pyridoxine; Substance Withdrawal Syndrome; Tryptophan

1978
Sleep and behavioral changes possibly reflecting central receptor hypersensitivity following catecholamine synthesis inhibition in man.
    Acta psychiatrica Scandinavica, 1977, Volume: 56, Issue:3

    Topics: Behavior; Bipolar Disorder; Dopamine; Humans; Levodopa; Norepinephrine; Receptors, Neurotransmitter; Sleep; Substance Withdrawal Syndrome; Tryptophan; Tyrosine

1977
Measures of physical dependence and involvement of serotonin in withdrawal symptomatology.
    Advances in experimental medicine and biology, 1977, Volume: 85A

    Topics: Alcoholism; Animals; Body Temperature; Brain Chemistry; Humans; Hydroxyindoleacetic Acid; Mice; Mice, Inbred C57BL; Serotonin; Substance Withdrawal Syndrome; Tryptophan

1977
Alteration in serum tyrosine and tryptophan concentrations associated with the induction of physical dependence on ethanol in mice.
    Biochemical pharmacology, 1978, Volume: 27, Issue:12

    Topics: Alcoholism; Animals; Humans; Male; Mice; Substance Withdrawal Syndrome; Tryptophan; Tyrosine

1978
The effects of ethanol on tryptophan pyrrolase activity and their comparison with those of phenobarbitone and morphine.
    Advances in experimental medicine and biology, 1975, Volume: 59

    Topics: Animals; Cricetinae; Ethanol; Fatty Acids, Nonesterified; Guinea Pigs; Humans; Kynurenine; Liver; Male; Morphine; Phenobarbital; Rats; Species Specificity; Substance Withdrawal Syndrome; Tryptophan; Tryptophan Oxygenase

1975
Is quinolinic acid an endogenous excitotoxin in alcohol withdrawal?
    Medical hypotheses, 1991, Volume: 36, Issue:2

    Topics: Alcoholism; Animals; Brain; Humans; Kynurenic Acid; Models, Neurological; Quinolinic Acid; Quinolinic Acids; Substance Withdrawal Syndrome; Synaptic Transmission; Tryptophan

1991
Neuroleptic malignant syndrome without neuroleptics.
    Journal of clinical psychopharmacology, 1990, Volume: 10, Issue:6

    Topics: Aged; Aged, 80 and over; Antiparkinson Agents; Carbidopa; Depressive Disorder; Drug Combinations; Drug Therapy, Combination; Female; Humans; Levodopa; Neuroleptic Malignant Syndrome; Parkinson Disease; Substance Withdrawal Syndrome; Tranylcypromine; Tryptophan

1990
Treatment of depression with pumpkin seeds.
    The British journal of psychiatry : the journal of mental science, 1990, Volume: 157

    Topics: Adult; Depressive Disorder; Fruit; Humans; Male; Seeds; Substance Withdrawal Syndrome; Tryptophan

1990
Cocaine withdrawal. An effective three-drug regimen.
    Postgraduate medicine, 1989, Volume: 85, Issue:4

    Topics: Amantadine; Cocaine; Humans; Lorazepam; Substance Withdrawal Syndrome; Substance-Related Disorders; Tryptophan

1989
Evaluation of L-tryptophan for treatment of insomnia: a review.
    Psychopharmacology, 1986, Volume: 89, Issue:1

    Topics: Adolescent; Adult; Aged; Drug Therapy, Combination; Drug Tolerance; Ethanol; Female; Humans; Hypnotics and Sedatives; Male; Middle Aged; Oxprenolol; Reaction Time; Sleep Initiation and Maintenance Disorders; Substance Withdrawal Syndrome; Tryptophan

1986
Effects of alcohol on tryptophan metabolism.
    Biochemical Society transactions, 1988, Volume: 16, Issue:3

    Topics: Animals; Ethanol; Humans; Rats; Serotonin; Substance Withdrawal Syndrome; Tryptophan

1988
Stepwise detoxification from cocaine. A promising regimen.
    Postgraduate medicine, 1988, Volume: 84, Issue:2

    Topics: Adolescent; Adult; Amantadine; Bromocriptine; Cocaine; Desipramine; Drug Therapy, Combination; Female; Humans; Levodopa; Male; Middle Aged; Substance Withdrawal Syndrome; Substance-Related Disorders; Tryptophan; Tyrosine

1988
Alcohol withdrawal reactions in mice: effects of drugs that modify neurotransmission.
    The Journal of pharmacology and experimental therapeutics, 1973, Volume: 186, Issue:1

    Topics: 5-Hydroxytryptophan; Acetates; Aminobutyrates; Animals; Atropine; Ethanol; Fenclonine; Humans; Male; Methyltyrosines; Mice; Neurotransmitter Agents; Nialamide; Phentolamine; Physostigmine; Picrotoxin; Propranolol; Pyrazoles; Reserpine; Serotonin; Substance Withdrawal Syndrome; Time Factors; Tryptophan

1973
The effects of chronic phenobarbitone administration and subsequent withdrawal on the activity of rat liver tryptohan pyrrolase and their resemblance to those of ethanol.
    The Biochemical journal, 1973, Volume: 135, Issue:3

    Topics: Animals; Depression, Chemical; Ethanol; Humans; Hydrocortisone; Injections, Intraperitoneal; Kynurenine; Liver; NAD; NADP; Phenobarbital; Rats; Sodium Chloride; Sodium Salicylate; Substance Withdrawal Syndrome; Time Factors; Tryptophan; Tryptophan Oxygenase

1973
Physical dependence on morphine fails to increase serotonin turnover rate in rat brain.
    Biochemical pharmacology, 1971, Volume: 20, Issue:4

    Topics: Animals; Body Temperature; Brain; Carbon Isotopes; Fenclonine; Humans; Male; Mathematics; Morphine Dependence; Nalorphine; Norepinephrine; Rats; Serotonin; Substance Withdrawal Syndrome; Tritium; Tryptophan; Tyrosine

1971
Evidence against a role of brain 5-hydroxytryptamine in the development of physical dependence upon morphine in mice.
    The Journal of pharmacology and experimental therapeutics, 1971, Volume: 179, Issue:3

    Topics: Animals; Body Weight; Brain Chemistry; Drug Interactions; Female; Fenclonine; Humans; Kinetics; Mice; Mice, Inbred Strains; Monoamine Oxidase Inhibitors; Morphine; Morphine Dependence; Motor Activity; Naloxone; Serotonin; Substance Withdrawal Syndrome; Tranylcypromine; Tryptophan

1971
The effects of drugs on barbiturate withdrawal convulsions in the rat.
    The Journal of pharmacy and pharmacology, 1970, Volume: 22, Issue:10

    Topics: Animals; Barbiturates; Chlordiazepoxide; Chlorpromazine; Ethanol; Ethosuximide; Female; Humans; Hydrazines; Hypnotics and Sedatives; Meprobamate; Methyltyrosines; Monoamine Oxidase Inhibitors; Morphine; Phenylalanine; Primidone; Rats; Reserpine; Seizures; Serotonin; Substance Withdrawal Syndrome; Tryptophan

1970