tryptophan and Colorectal Cancer

tryptophan has been researched along with Colorectal Cancer in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (19.05)29.6817
2010's4 (19.05)24.3611
2020's13 (61.90)2.80

Authors

AuthorsStudies
Chakravarti, D; Chen, P; DePinho, RA; Hsu, WH; Jiang, S; LaBella, KA; Lee, R; Li, J; Spring, DJ; Wang, YA; Wu, CJ; Zhao, D1
Chen, X; Huang, C; Huang, H; Jian, Y; Li, F; Li, Y; Liao, W; Lin, C; Liu, G; Mo, S; Shi, D; Song, L; Wang, J; Wang, YA; Wu, X; Zhang, C; Zhang, D; Zhang, H1
Bours, MJL; Breukink, SO; Brezina, S; Eussen, SJPM; Gigic, B; Gsur, A; Holthuijsen, DDB; Janssen-Heijnen, MLG; Keulen, ETP; Kok, DE; Midttun, Ø; Ose, J; Roekel, EHV; Ueland, PM; Ulrich, CM; Weijenberg, MP1
Chen, H; Chen, HM; Chen, J; Chen, YX; Cui, Y; Fang, JY; Han, JX; Hong, J; Kang, ZR; Li, J; Liu, Q; Lu, S; Su, W; Tao, ZH; Wang, JL; Wang, M; Wang, Z; Xie, Y; Xiong, H; Xu, J; Yu, CY; Zhang, L; Zhao, E; Zhou, CB; Zou, TH1
Chen, W; Liu, Y; Lu, W; Pan, T; Pei, Z; Wang, H1
Chen, H; Du, W; Hong, X; Huang, X; Su, W; Sun, D; Sun, T; Wang, J; Xiong, H; Yan, T; Yang, C; Yu, T; Zhou, C1
Gezer, U; Hakan, MT; Horozoglu, C; Kulle, CB; Özgür, E; Yaylim, I; Yörüker, EE; Zor, DS1
Chen, W; Gao, S; Li, X; Lv, J; Wang, Z; Yang, Y; Zhang, F; Zhong, R1
Langner, E; Makuch-Kocka, A; Plech, T; Pożarowski, P; Szalast, K; Walczak, K1
Almeida, J; Barcherini, V; Lopes, EA; Magalhães E Silva, D; Mori, M; Santos, MMM; Saraiva, L; Wang, M; Wang, S1
Wu, KK1
Cao, T; Li, X; Lin, B; Liu, C; Luo, S; Shi, J; Wang, S; Zhang, X; Zheng, T; Zhou, M1
Ala, M1
Kibi, M; Kobayashi, T; Kodama, Y; Nishiumi, S; Yoshida, M1
Engin, A; Engin, AB; Karahalil, B; Karakaya, AE1
Bessede, A; Bodet, D; Debled, M; Eimer, S; Fallarino, F; Guillemin, GJ; Italiano, A; MacGrogan, G; Platten, M; Prendergast, GC; Puccetti, P; Soubeyran, I; Velasco, V; Veldhoen, M1
Dursun, A; Engin, A; Engin, AB; Gonul, II; Karamercan, A; Sepici Dincel, A1
Berndt, SI; Chanock, SJ; Hayes, RB; Huang, WY; Weissfeld, JL; Yeager, M1
Allen-Mersh, TG; Fuchs, D; Glover, C; Henderson, DC; Huang, A; Widner, B2
Abdel-Rahman, SZ; Bondy, ML; El-Badawy, SA; Khaled, HM; Levin, B; Omar, S; Seifeldin, IA; Soliman, AS1

Reviews

3 review(s) available for tryptophan and Colorectal Cancer

ArticleYear
Indole metabolites and colorectal cancer: Gut microbial tryptophan metabolism, host gut microbiome biomarkers, and potential intervention mechanisms.
    Microbiological research, 2023, Volume: 272

    Topics: Bacteria; Biomarkers; Colorectal Neoplasms; Gastrointestinal Microbiome; Humans; Indoles; Tryptophan

2023
Cytoguardin: A Tryptophan Metabolite against Cancer Growth and Metastasis.
    International journal of molecular sciences, 2021, Apr-26, Volume: 22, Issue:9

    Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line; Cell Movement; Cell Proliferation; Colorectal Neoplasms; Cyclooxygenase 2; Fibroblasts; Humans; Liver Neoplasms; Matrix Metalloproteinases; Mice; Neoplasm Metastasis; Neoplasms; Pancreatic Neoplasms; Serotonin; Tryptophan

2021
Tryptophan metabolites modulate inflammatory bowel disease and colorectal cancer by affecting immune system.
    International reviews of immunology, 2022, Volume: 41, Issue:3

    Topics: Colitis; Colorectal Neoplasms; Humans; Indoles; Inflammatory Bowel Diseases; Kynurenine; Serotonin; Th17 Cells; Tryptophan

2022

Other Studies

18 other study(ies) available for tryptophan and Colorectal Cancer

ArticleYear
Synthetic Essentiality of Tryptophan 2,3-Dioxygenase 2 in APC-Mutated Colorectal Cancer.
    Cancer discovery, 2022, 07-06, Volume: 12, Issue:7

    Topics: Adenomatous Polyposis Coli; beta Catenin; Colorectal Neoplasms; Dioxygenases; Humans; Tryptophan; Tryptophan Oxygenase; Tumor Microenvironment; Wnt Signaling Pathway

2022
USP14 promotes tryptophan metabolism and immune suppression by stabilizing IDO1 in colorectal cancer.
    Nature communications, 2022, 09-26, Volume: 13, Issue:1

    Topics: Animals; Colorectal Neoplasms; Deubiquitinating Enzymes; Indoleamine-Pyrrole 2,3,-Dioxygenase; Mice; Proteasome Endopeptidase Complex; Receptors, Aryl Hydrocarbon; Tryptophan; Ubiquitin Thiolesterase

2022
Longitudinal Associations of Adherence to the Dietary World Cancer Research Fund/American Institute for Cancer Research (WCRF/AICR) and Dutch Healthy Diet (DHD) Recommendations with Plasma Kynurenines in Colorectal Cancer Survivors after Treatment.
    Nutrients, 2022, Dec-03, Volume: 14, Issue:23

    Topics: Cancer Survivors; Colorectal Neoplasms; Diet; Diet, Healthy; Humans; Kynurenic Acid; Tryptophan; United States

2022
Microbiota-derived tryptophan catabolites mediate the chemopreventive effects of statins on colorectal cancer.
    Nature microbiology, 2023, Volume: 8, Issue:5

    Topics: Colorectal Neoplasms; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Limosilactobacillus reuteri; Microbiota; Retrospective Studies; Tryptophan

2023
Metformin Reprograms Tryptophan Metabolism to Stimulate CD8+ T-cell Function in Colorectal Cancer.
    Cancer research, 2023, 07-14, Volume: 83, Issue:14

    Topics: CD8-Positive T-Lymphocytes; Colorectal Neoplasms; Humans; Immunosuppression Therapy; Metformin; Tryptophan; Tumor Microenvironment

2023
Plasma Levels of Kynurenine, Soluble OX40 and Mir-138-5p Are Associated With Tumor-infiltrating Lymphocytes in Colorectal Cancer: An Exploratory Study.
    Anticancer research, 2023, Volume: 43, Issue:7

    Topics: B7-H1 Antigen; Colorectal Neoplasms; Humans; Kynurenine; Lymphocytes; MicroRNAs; Tryptophan; Tumor Microenvironment

2023
Profiling the metabolic disorder and detection of colorectal cancer based on targeted amino acids metabolomics.
    Journal of translational medicine, 2023, Nov-17, Volume: 21, Issue:1

    Topics: Amino Acids; Biomarkers, Tumor; Colorectal Neoplasms; Glutamates; Humans; Metabolomics; Sarcosine; Tryptophan

2023
A Tryptophan Metabolite, 8-Hydroxyquinaldic Acid, Exerts Antiproliferative and Anti-Migratory Effects on Colorectal Cancer Cells.
    Molecules (Basel, Switzerland), 2020, Apr-03, Volume: 25, Issue:7

    Topics: Antigens, CD; beta Catenin; Cadherins; Cell Cycle Proteins; Cell Line, Tumor; Cell Movement; Cell Proliferation; Colorectal Neoplasms; Gene Expression Regulation, Neoplastic; HT29 Cells; Humans; Kynurenic Acid; Mitochondria; Tryptophan; Wnt Signaling Pathway

2020
Potency and Selectivity Optimization of Tryptophanol-Derived Oxazoloisoindolinones: Novel p53 Activators in Human Colorectal Cancer.
    ChemMedChem, 2021, 01-08, Volume: 16, Issue:1

    Topics: Antineoplastic Agents; Binding Sites; Cell Line, Tumor; Cell Proliferation; Colorectal Neoplasms; Drug Design; Humans; Molecular Docking Simulation; Oxindoles; Proto-Oncogene Proteins c-mdm2; Structure-Activity Relationship; Tryptophan; Tumor Suppressor Protein p53

2021
STING agonist and IDO inhibitor combination therapy inhibits tumor progression in murine models of colorectal cancer.
    Cellular immunology, 2021, Volume: 366

    Topics: Adenocarcinoma; Animals; Antineoplastic Combined Chemotherapy Protocols; Benzimidazoles; Carcinogenesis; CD8-Positive T-Lymphocytes; Cell Line, Tumor; Cell Movement; Cell Proliferation; Colorectal Neoplasms; Disease Models, Animal; Disease Progression; Female; Humans; Immune Checkpoint Inhibitors; Immunotherapy; Indoleamine-Pyrrole 2,3,-Dioxygenase; Membrane Proteins; Mice; Mice, Inbred C57BL; Myeloid-Derived Suppressor Cells; Neoplasm Transplantation; Programmed Cell Death 1 Receptor; Tryptophan

2021
GC/MS and LC/MS-based Tissue Metabolomic Analysis Detected Increased Levels of Antioxidant Metabolites in Colorectal Cancer.
    The Kobe journal of medical sciences, 2019, May-24, Volume: 65, Issue:1

    Topics: Antioxidants; Chromatography, Liquid; Colorectal Neoplasms; Female; Gas Chromatography-Mass Spectrometry; Humans; Male; Mass Spectrometry; Metabolomics; Middle Aged; NAD; Tryptophan

2019
Helicobacter pylori and serum kynurenine-tryptophan ratio in patients with colorectal cancer.
    World journal of gastroenterology, 2015, Mar-28, Volume: 21, Issue:12

    Topics: Antibodies, Bacterial; Biomarkers, Tumor; Case-Control Studies; Chromatography, High Pressure Liquid; Colorectal Neoplasms; Enzyme-Linked Immunosorbent Assay; Female; Helicobacter Infections; Helicobacter pylori; Humans; Immunoglobulin G; Kynurenine; Male; Middle Aged; Neopterin; Prospective Studies; Tryptophan; Tumor Escape

2015
Accumulation of an endogenous tryptophan-derived metabolite in colorectal and breast cancers.
    PloS one, 2015, Volume: 10, Issue:4

    Topics: Breast Neoplasms; Colorectal Neoplasms; Humans; Tryptophan

2015
Relationship between indoleamine 2,3-dioxygenase activity and lymphatic invasion propensity of colorectal carcinoma.
    World journal of gastroenterology, 2016, Apr-07, Volume: 22, Issue:13

    Topics: Biomarkers, Tumor; Biopterins; Carcinoma; Case-Control Studies; Chromatography, High Pressure Liquid; Colorectal Neoplasms; Enzyme-Linked Immunosorbent Assay; Female; Humans; Immunohistochemistry; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Lymphatic Metastasis; Lymphatic System; Male; Middle Aged; Neoplasm Invasiveness; Neopterin; Predictive Value of Tests; Tryptophan; Urinalysis

2016
Genetic variants in frizzled-related protein (FRZB) and the risk of colorectal neoplasia.
    Cancer causes & control : CCC, 2009, Volume: 20, Issue:4

    Topics: Adenoma; Algorithms; Alleles; Amino Acid Substitution; Black or African American; Case-Control Studies; Colorectal Neoplasms; Confidence Intervals; DNA, Neoplasm; Early Detection of Cancer; Female; Gene Frequency; Genetic Variation; Glycine; Glycoproteins; Haplotypes; Homozygote; Humans; Intracellular Signaling Peptides and Proteins; Likelihood Functions; Linkage Disequilibrium; Logistic Models; Male; Mass Screening; Odds Ratio; Polymorphism, Single Nucleotide; Risk Factors; Sigmoidoscopy; Tryptophan; White People

2009
Tryptophan and quality of life in colorectal cancer.
    Advances in experimental medicine and biology, 2003, Volume: 527

    Topics: Case-Control Studies; Colorectal Neoplasms; Humans; Kynurenine; Quality of Life; Th1 Cells; Tryptophan

2003
Inheritance of the 194Trp and the 399Gln variant alleles of the DNA repair gene XRCC1 are associated with increased risk of early-onset colorectal carcinoma in Egypt.
    Cancer letters, 2000, Oct-16, Volume: 159, Issue:1

    Topics: Adult; Age of Onset; Alleles; Amino Acid Sequence; Case-Control Studies; Colorectal Neoplasms; DNA; DNA Repair; DNA-Binding Proteins; Egypt; Female; Gene Frequency; Genetic Variation; Genotype; Glutamine; Humans; Male; Middle Aged; Odds Ratio; Pilot Projects; Polymorphism, Genetic; Polymorphism, Restriction Fragment Length; Risk Factors; Rural Population; Tryptophan; Urban Population; X-ray Repair Cross Complementing Protein 1

2000
Serum tryptophan decrease correlates with immune activation and impaired quality of life in colorectal cancer.
    British journal of cancer, 2002, Jun-05, Volume: 86, Issue:11

    Topics: Adenocarcinoma; Aged; Colonic Neoplasms; Colorectal Neoplasms; Humans; Interleukin-6; Kynurenine; Liver Neoplasms; Middle Aged; Quality of Life; Rectal Neoplasms; Regression Analysis; Survival Analysis; Tryptophan; Tumor Necrosis Factor-alpha

2002