tryptophan and Colonic Neoplasms

tryptophan has been researched along with Colonic Neoplasms in 32 studies

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-19908 (25.00)18.7374
1990's2 (6.25)18.2507
2000's1 (3.13)29.6817
2010's12 (37.50)24.3611
2020's9 (28.13)2.80

Authors

AuthorsStudies
Dang, C; Guo, J; Jia, H; Li, J; Li, M; Li, R; Li, X; Li, Y; Liu, Z; Wang, S; Zhang, Y; Zhao, T; Zhu, G1
Bagiński, M; Maciejewska, N; Makowiec, S; Olszewski, M; Ryczkowska, M; Witkowska, M1
Brabletz, T; Chang, BJ; Conacci-Sorrell, M; Danuser, G; Fiolka, R; Garcia, R; Hao, YH; Kim, J; Lafita-Navarro, MC; Perez-Castro, L; Saponzik, E; Segal, D; Venkateswaran, N; Xu, L1
Borenstein-Auerbach, N; Brabletz, T; Braverman, J; Conacci-Sorrell, M; DeBerardinis, RJ; Hao, YH; Kilgore, JA; Kim, M; Lafita-Navarro, MC; Lesner, NP; Mishra, P; Perez-Castro, L; Shay, JW; Venkateswaran, N; Williams, NS; Yilmaz, OH1
Crosignani, S; Driessens, G; Frederix, K; Hoffmann, D; Pilotte, L; Preillon, J; Schramme, F; Stroobant, V; Van den Eynde, BJ1
Andry, C; Arinze, N; Belghasem, M; Chitalia, VC; Francis, JM; Lee, N; Lyle, C; Napolene, MA; Ravid, K; Richards, S; Roth, D; Spencer, C; Thompson, C; Walker, J; Whelan, SA; Yin, W1
Bhutia, YD; Brown, TP; Ganapathy, V; Sikder, MOF; Sivaprakasam, S; Thangaraju, M1
Allred, CD; Callaway, E; Chapkin, RS; DeLuca, JAA; Garcia-Vilarato, E; Jayaraman, A; Landrock, KK; Lee, K; Menon, R; Safe, SH; Yang, F1
Greathouse, KL; Wyatt, M1
Bi, F; Tang, Q; Xia, H; Xu, H; Ye, D; Zhang, C1
Achaintre, D; Ardanaz, E; Baierl, A; Brezina, S; Bueno-de-Mesquita, B; Colorado-Yohar, SM; Geijsen, AJMR; Gicquiau, A; Gigic, B; Gsur, A; Gumpenberger, T; Gunter, MJ; Habermann, N; Kaaks, R; Kampman, E; Katzke, V; Keski-Rahkonen, P; Krogh, V; Murphy, N; Ose, J; Papadimitriou, N; Sánchez, MJ; Scalbert, A; Schulze, MB; Travis, RC; Ueland, PM; Ulrich, CM; van Roekel, EH; Weiderpass, E; Weijenberg, MP1
Hwang, WB; Kim, DJ; Lee, EJ; Lee, JM; Park, JH1
Ding, Y; Du, Q; Hu, R; Liu, X; Zhang, X; Zhou, W1
Duan, G; Lu, F; Lv, L; Qi, Y; Wang, R; Yan, H; Zhang, T; Zhao, L; Zhou, F1
Alves, MG; Espadinha, M; Loureiro, JB; Raimundo, L; Santos, MMM; Saraiva, L; Soares, J1
Ando, T; Arioka, Y; Ito, H; Saito, K; Seishima, M1
Bessa, C; Bisio, A; Fernandes, J; Gomes, C; Gomes, S; Gonçalves, J; Inga, A; Monteiro, Â; Pereira, C; Pereira, NA; Queiroz, G; Raimundo, L; Reis, F; Santos, MM; Saraiva, L; Soares, J1
Chen, YL; Huang, TT; Lai, MD; Lin, CC; Lin, CM; Weng, TY; Wu, CL; Yang, HJ; Yen, MC1
Hara, T; Hoshi, M; Ito, H; Moriwaki, H; Nagano, J; Ninomiya, S; Ogawa, K; Saito, K; Sakai, H; Seishima, M; Shimizu, M; Tanaka, T; Tsurumi, H1
Banerjee, B; Gavini, H; Graves, LR; Nfonsam, V; Pugh, J; Renkoski, T; Rial, NS; Tiwari, P; Tsikitis, VL; Utzinger, U1
Mangindaan, REP; Namikoshi, M; Nishikawa, T; Rotinsulu, H; Wewengkang, DS; Yamazaki, H1
Hill, MJ; Thompson, MH1
Fukui, H; Kashiwagi, T; Kawata, S; Kozuka, T; Matsuda, Y; Nishimura, T; Shirai, Y1
Alvares, CP; Glenn, KS; Karnes, WE; Rand, A; Thibodeau, SM; White, MB1
Allen-Mersh, TG; Fuchs, D; Glover, C; Henderson, DC; Huang, A; Widner, B1
Hili, MJ1
Chung, KT; Fulk, GE; Slein, MW1
Howell, MA1
Jones, RD; Karlin, DA; Lorentz, O; Mastromarino, AJ; Stroehlein, JR1
Dresviannikov, BB; Khanina, SB; Kiparisov, LN1
Böttcher, RF; Wolff, H1
Hollins, B; Howard, CH; Rudman, D; Treadwell, PE; Vogler, WR1

Reviews

1 review(s) available for tryptophan and Colonic Neoplasms

ArticleYear
Targeting Dietary and Microbial Tryptophan-Indole Metabolism as Therapeutic Approaches to Colon Cancer.
    Nutrients, 2021, Apr-03, Volume: 13, Issue:4

    Topics: Basic Helix-Loop-Helix Transcription Factors; Carcinogenesis; Colon; Colonic Neoplasms; Combined Modality Therapy; Enzyme Inhibitors; Gastrointestinal Microbiome; Host Microbial Interactions; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Indoles; Intestinal Mucosa; Kynurenine; Metabolic Networks and Pathways; Probiotics; Proto-Oncogene Proteins c-myc; Receptors, Aryl Hydrocarbon; Symbiosis; Tryptophan; Tumor Escape; Tumor Microenvironment

2021

Other Studies

31 other study(ies) available for tryptophan and Colonic Neoplasms

ArticleYear
D-MT prompts the anti-tumor effect of oxaliplatin by inhibiting IDO expression in a mouse model of colon cancer.
    International immunopharmacology, 2021, Volume: 101, Issue:Pt A

    Topics: Animals; Antineoplastic Agents; Blotting, Western; Cell Line, Tumor; Colonic Neoplasms; Drug Synergism; Enzyme-Linked Immunosorbent Assay; Female; Flow Cytometry; Fluorescent Antibody Technique; Indoleamine-Pyrrole 2,3,-Dioxygenase; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Oxaliplatin; Tryptophan

2021
From tryptophan to novel mitochondria-disruptive agent, synthesis and biological evaluation of 1,2,3,6-tetrasubstituted carbazoles.
    European journal of medicinal chemistry, 2022, Aug-05, Volume: 238

    Topics: Antineoplastic Agents; Apoptosis; Bone Neoplasms; Carbazoles; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Humans; Mitochondria; Osteosarcoma; Reactive Oxygen Species; Tryptophan

2022
The AHR target gene scinderin activates the WNT pathway by facilitating the nuclear translocation of β-catenin.
    Journal of cell science, 2022, 10-15, Volume: 135, Issue:20

    Topics: Actins; beta Catenin; Colonic Neoplasms; Cytochrome P-450 CYP1A1; Environmental Pollutants; Humans; Kynurenine; Ligands; Polychlorinated Dibenzodioxins; Receptors, Aryl Hydrocarbon; RNA; Tryptophan; Wnt Signaling Pathway

2022
MYC promotes tryptophan uptake and metabolism by the kynurenine pathway in colon cancer.
    Genes & development, 2019, 09-01, Volume: 33, Issue:17-18

    Topics: Amino Acid Transport System ASC; Antineoplastic Agents; Arylformamidase; Cell Line; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Gene Expression Regulation, Neoplastic; Humans; Indoles; Kynurenine; Large Neutral Amino Acid-Transporter 1; Minor Histocompatibility Antigens; Oximes; Proto-Oncogene Mas; Proto-Oncogene Proteins c-myc; Sulfonamides; Tryptophan

2019
Inhibition of Tryptophan-Dioxygenase Activity Increases the Antitumor Efficacy of Immune Checkpoint Inhibitors.
    Cancer immunology research, 2020, Volume: 8, Issue:1

    Topics: Animals; Antineoplastic Agents, Immunological; Cell Line, Tumor; Colonic Neoplasms; CTLA-4 Antigen; Drug Synergism; Enzyme Inhibitors; Humans; Kynurenine; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Neoplasms, Experimental; Programmed Cell Death 1 Receptor; Small Molecule Libraries; Tryptophan; Tryptophan Oxygenase

2020
Metabolites in a mouse cancer model enhance venous thrombogenicity through the aryl hydrocarbon receptor-tissue factor axis.
    Blood, 2019, 12-26, Volume: 134, Issue:26

    Topics: Animals; Colonic Neoplasms; Disease Models, Animal; Female; Humans; Male; Metabolome; Mice; Mice, Nude; Plasminogen Activator Inhibitor 1; Receptors, Aryl Hydrocarbon; Signal Transduction; Thromboplastin; Tryptophan; Venous Thromboembolism; Xenograft Model Antitumor Assays

2019
SLC6A14, a Na+/Cl--coupled amino acid transporter, functions as a tumor promoter in colon and is a target for Wnt signaling.
    The Biochemical journal, 2020, 04-30, Volume: 477, Issue:8

    Topics: Amino Acid Transport Systems; Animals; Antineoplastic Agents; Apoptosis; Autophagy; Carcinogens; Cell Line, Tumor; Cell Proliferation; Colon; Colonic Neoplasms; Female; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; TOR Serine-Threonine Kinases; Tryptophan; Wnt Signaling Pathway

2020
Effect of diet and intestinal AhR expression on fecal microbiome and metabolomic profiles.
    Microbial cell factories, 2020, Nov-30, Volume: 19, Issue:1

    Topics: Akkermansia; Animals; Basic Helix-Loop-Helix Transcription Factors; Colonic Neoplasms; Diet; DNA, Bacterial; Feces; Female; Gastrointestinal Microbiome; Intestinal Mucosa; Metabolome; Mice; Mice, Inbred C57BL; Mice, Knockout; Models, Animal; Receptors, Aryl Hydrocarbon; RNA, Ribosomal, 16S; Tryptophan

2020
Targeting SERT promotes tryptophan metabolism: mechanisms and implications in colon cancer treatment.
    Journal of experimental & clinical cancer research : CR, 2021, May-18, Volume: 40, Issue:1

    Topics: Animals; Cell Line, Tumor; Colonic Neoplasms; Female; Humans; Mice; Mice, Nude; Serotonin Plasma Membrane Transport Proteins; Signal Transduction; Transfection; Tryptophan

2021
Circulating tryptophan metabolites and risk of colon cancer: Results from case-control and prospective cohort studies.
    International journal of cancer, 2021, 11-01, Volume: 149, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Case-Control Studies; Colonic Neoplasms; Female; Humans; Kynurenine; Logistic Models; Male; Middle Aged; Prospective Studies; Risk Factors; Serotonin; Tryptophan

2021
Kynurenine promotes the goblet cell differentiation of HT-29 colon carcinoma cells by modulating Wnt, Notch and AhR signals.
    Oncology reports, 2018, Volume: 39, Issue:4

    Topics: Basic Helix-Loop-Helix Transcription Factors; beta Catenin; Cell Differentiation; Cell Proliferation; Colonic Neoplasms; Gene Expression Regulation, Neoplastic; Goblet Cells; HT29 Cells; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Receptor, Notch1; Receptors, Aryl Hydrocarbon; Transcription Factor HES-1; Tryptophan; Wnt Signaling Pathway

2018
1-L-MT, an IDO inhibitor, prevented colitis-associated cancer by inducing CDC20 inhibition-mediated mitotic death of colon cancer cells.
    International journal of cancer, 2018, 09-15, Volume: 143, Issue:6

    Topics: Animals; Apoptosis; Azoxymethane; Carcinogens; Cdc20 Proteins; Cell Cycle; Cell Proliferation; Colitis; Colonic Neoplasms; Enzyme Inhibitors; Homeodomain Proteins; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitosis; Tryptophan; Tumor Cells, Cultured

2018
Celastrol Suppresses Tryptophan Catabolism in Human Colon Cancer Cells as Revealed by Metabolic Profiling and Targeted Metabolite Analysis.
    Biological & pharmaceutical bulletin, 2018, Volume: 41, Issue:8

    Topics: Antineoplastic Agents; Cell Survival; Colonic Neoplasms; HCT116 Cells; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Kynurenine; Metabolomics; Pentacyclic Triterpenes; Triterpenes; Tryptophan

2018
Improving anticancer activity towards colon cancer cells with a new p53-activating agent.
    British journal of pharmacology, 2018, Volume: 175, Issue:20

    Topics: Antineoplastic Agents; Cell Cycle Proteins; Cell Line, Tumor; Cell Movement; Colonic Neoplasms; Doxorubicin; Drug Resistance, Neoplasm; Humans; Lactams; Nuclear Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-mdm2; Tryptophan; Tumor Suppressor Protein p53

2018
Inhibition of indoleamine 2,3-dioxygenase activity enhances the anti-tumour effects of a Toll-like receptor 7 agonist in an established cancer model.
    Immunology, 2015, Volume: 144, Issue:4

    Topics: Aminoquinolines; Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Colonic Neoplasms; Dose-Response Relationship, Drug; Female; Imiquimod; Indoleamine-Pyrrole 2,3,-Dioxygenase; Lymph Nodes; Lymphocytes, Tumor-Infiltrating; Membrane Glycoproteins; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Signal Transduction; Th1 Cells; Thymoma; Thyroid Neoplasms; Time Factors; Toll-Like Receptor 7; Tryptophan; Tumor Burden

2015
Reactivation of wild-type and mutant p53 by tryptophanolderived oxazoloisoindolinone SLMP53-1, a novel anticancer small-molecule.
    Oncotarget, 2016, Jan-26, Volume: 7, Issue:4

    Topics: Animals; Antineoplastic Agents; Apoptosis; Blotting, Western; Cell Movement; Cell Proliferation; Colonic Neoplasms; High-Throughput Screening Assays; Humans; Immunoenzyme Techniques; Isoindoles; Mice; Mice, Inbred BALB C; Mice, Nude; Mutation; Oxazoles; Piperidones; Rats; Rats, Wistar; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Small Molecule Libraries; Tryptophan; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays

2016
A combination of the metabolic enzyme inhibitor APO866 and the immune adjuvant L-1-methyl tryptophan induces additive antitumor activity.
    Experimental biology and medicine (Maywood, N.J.), 2010, Volume: 235, Issue:7

    Topics: Acrylamides; Animals; Antineoplastic Agents; Cell Line, Tumor; Colonic Neoplasms; Drug Synergism; Drug Therapy, Combination; Female; Indoleamine-Pyrrole 2,3,-Dioxygenase; Liver Neoplasms, Experimental; Mice; Mice, Inbred C3H; Mice, Inbred ICR; Mice, Inbred NOD; Neoplasms, Experimental; Nicotinamide Phosphoribosyltransferase; Piperidines; Tryptophan; Urinary Bladder Neoplasms

2010
Suppression of azoxymethane-induced colonic preneoplastic lesions in rats by 1-methyltryptophan, an inhibitor of indoleamine 2,3-dioxygenase.
    Cancer science, 2012, Volume: 103, Issue:5

    Topics: Animals; Anticarcinogenic Agents; Azoxymethane; Carcinogens; Colonic Neoplasms; Indoleamine-Pyrrole 2,3,-Dioxygenase; Male; Precancerous Conditions; Rats; Rats, Inbred F344; Tryptophan

2012
Tryptophan autofluorescence imaging of neoplasms of the human colon.
    Journal of biomedical optics, 2012, Volume: 17, Issue:1

    Topics: Adenocarcinoma; Adult; Colonic Neoplasms; Diagnostic Imaging; Female; Histocytochemistry; Humans; Image Processing, Computer-Assisted; Intestinal Mucosa; Male; Middle Aged; Spectrometry, Fluorescence; Tryptophan

2012
Two new tryptamine derivatives, leptoclinidamide and (-)-leptoclinidamine B, from an Indonesian ascidian Leptoclinides dubius.
    Marine drugs, 2012, Volume: 10, Issue:2

    Topics: Acetylation; Alkaloids; Animals; Anti-Bacterial Agents; Antineoplastic Agents; Aquatic Organisms; Cell Line, Tumor; Colonic Neoplasms; Drug Discovery; Escherichia coli; Humans; Indian Ocean; Indole Alkaloids; Indonesia; Jurkat Cells; Ketoses; Leukemia, T-Cell; Molecular Structure; Stereoisomerism; Tryptamines; Tryptophan; Urochordata

2012
Some etiological factors in large-bowel cancer.
    IARC scientific publications, 1982, Issue:39

    Topics: Adenoma; Bile Acids and Salts; Colonic Neoplasms; Environment; Fatty Acids, Unsaturated; Humans; Nitrosamines; Steroids; Tryptophan; Tyrosine

1982
Metastasis of hepatocellular carcinoma to the colon demonstrated by Tc-99m PMT scintigraphy.
    Clinical nuclear medicine, 1993, Volume: 18, Issue:6

    Topics: Carcinoma, Hepatocellular; Colonic Neoplasms; Humans; Liver Neoplasms; Male; Middle Aged; Organotechnetium Compounds; Pyridoxal; Radionuclide Imaging; Tryptophan

1993
p53 functional loss in a colon cancer cell line with two missense mutations (218leu and 248trp) on separate alleles.
    Cancer letters, 1996, Jan-02, Volume: 98, Issue:2

    Topics: Alleles; Cell Division; Colonic Neoplasms; DNA Damage; DNA, Neoplasm; ErbB Receptors; Genes, p53; Heterozygote; Humans; Leucine; Mutation; Sequence Analysis, DNA; Tryptophan; Tumor Cells, Cultured; Tumor Suppressor Protein p53

1996
Serum tryptophan decrease correlates with immune activation and impaired quality of life in colorectal cancer.
    British journal of cancer, 2002, Jun-05, Volume: 86, Issue:11

    Topics: Adenocarcinoma; Aged; Colonic Neoplasms; Colorectal Neoplasms; Humans; Interleukin-6; Kynurenine; Liver Neoplasms; Middle Aged; Quality of Life; Rectal Neoplasms; Regression Analysis; Survival Analysis; Tryptophan; Tumor Necrosis Factor-alpha

2002
Intestinal bacteria and cancer.
    Annali dell'Istituto superiore di sanita, 1979, Volume: 15, Issue:1

    Topics: Amino Acids; Bacteria; Bile Acids and Salts; Carcinogens; Cholesterol; Colonic Neoplasms; Humans; Intestine, Large; Phosphatidylcholines; Rectal Neoplasms; Tryptophan

1979
Tryptophanase of fecal flora as a possible factor in the etiology of colon cancer.
    Journal of the National Cancer Institute, 1975, Volume: 54, Issue:5

    Topics: Bacteroides; Citrobacter; Colonic Neoplasms; Diet; Enzyme Induction; Enzyme Repression; Escherichia; Feces; Glucose; Humans; Indoles; Intestines; Lyases; Pyruvates; Tryptophan; Tryptophanase

1975
The association between colorectal cancer and breast cancer.
    Journal of chronic diseases, 1976, Volume: 29, Issue:4

    Topics: Breast Neoplasms; Colonic Neoplasms; Diet; Dietary Fats; Female; Food; Humans; Male; Rectal Neoplasms; Risk; Transients and Migrants; Tryptophan; United States

1976
Fecal skatole and indole and breath methane and hydrogen in patients with large bowel polyps or cancer.
    Journal of cancer research and clinical oncology, 1985, Volume: 109, Issue:2

    Topics: Bacteria; Breath Tests; Colon; Colonic Neoplasms; Colonic Polyps; Feces; Humans; Hydrogen; Indoles; Intestinal Absorption; Methane; Rectal Neoplasms; Skatole; Tryptophan

1985
[Conservative treatment in carcinoid].
    Klinicheskaia meditsina, 1970, Volume: 48, Issue:5

    Topics: Adenoma, Basophil; Carcinoid Tumor; Cecum; Colonic Neoplasms; Female; Glucocorticoids; Heart Neoplasms; Humans; Ileum; Intestinal Neoplasms; Isoniazid; Liver Neoplasms; Malignant Carcinoid Syndrome; Middle Aged; Neoplasm Metastasis; Pituitary Neoplasms; Serotonin; Serotonin Antagonists; Time Factors; Tryptophan

1970
[Significance of tryptophan-perchloric acid reaction in malignant tumors].
    Zeitschrift fur experimentelle Chirurgie, 1971, Volume: 4, Issue:5

    Topics: Appendicitis; Breast Neoplasms; Bronchial Neoplasms; Cholelithiasis; Colonic Neoplasms; Esophageal Neoplasms; Hernia, Inguinal; Humans; Indicators and Reagents; Neoplasms; Osteomyelitis; Perchlorates; Rectal Neoplasms; Stomach Neoplasms; Stomach Ulcer; Tryptophan; Tuberculosis, Pulmonary

1971
An abnormal orosomucoid in the plasma of patients with neoplastic disease.
    Cancer research, 1972, Volume: 32, Issue:9

    Topics: Adult; Amino Acids; Carcinoma, Bronchogenic; Chromatography, Gel; Chromatography, Ion Exchange; Colonic Neoplasms; Female; Glucosamine; Glycoproteins; Hexoses; Humans; Immunodiffusion; Immunoelectrophoresis; Leukemia, Lymphoid; Leukemia, Myeloid, Acute; Male; Melanoma; Middle Aged; Neoplasm Metastasis; Neoplasms; Neuraminic Acids; Ovarian Neoplasms; Tryptophan

1972